08-02-2018 дата публикации
Номер: US20180036275A1
The present invention concerns a combination of a retinoid and a diol and polyunsaturated fatty acid ester, a dermatological or dermocosmetic composition containing such a combination and use of same in the treatment of acne and the prevention of retentional lesions. The present invention also concerns a retinoid, optionally in combination with a diol and polyunsaturated fatty acid ester, for use in the prevention of retentional lesions. 118-. (canceled)20. The combination according to claim 19 , wherein n is between 1 and 10.21. The combination according to claim 20 , wherein n is 1 claim 20 , 2 claim 20 , 3 claim 20 , 4 or 5.22. The combination according to claim 19 , wherein m is 0 or 1.23. The combination according to claim 19 , wherein the polyunsaturated fatty acid is selected from α-linolenic acid claim 19 , stearidonic acid claim 19 , eicosatrienoic acid claim 19 , eicosatetraenoic acid claim 19 , eicosapentaenoic acid claim 19 , docosapentaenoic acid claim 19 , docosahexaenoic acid claim 19 , tetracosapentaenoic acid claim 19 , tetracosahexaenoic acid claim 19 , linoleic acid claim 19 , gamma-linolenic acid claim 19 , eicosadienoic acid claim 19 , dihomo-gamma-linolenic acid claim 19 , arachidonic acid claim 19 , docosatetraenoic acid claim 19 , docosapentaenoic acid claim 19 , adrenic acid and calendic acid.24. The combination according to claim 23 , wherein the polyunsaturated fatty acid is α-linolenic acid claim 23 , stearidonic acid or linoleic acid.26. The combination according to claim 19 , wherein the retinoid is selected from retinol claim 19 , retinaldehyde claim 19 , and retinoic acid in its various stereoisomeric forms.28. A method for preventing the formation of retentional lesions or for treating acne comprising the administration to a patient in need thereof of an effective amount of a combination according to .29. A dermatological or dermocosmetic composition comprising at least one combination according to in association with at least one ...
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