CROSS-LINKED BIOACTIVE HYDROGEL MATRICES

The present invention is directed to a stabilized cross-linked hydrogel matrix comprising a first high molecular weight component and a second high molecular weight component that are covalently linked, and at least one stabilizing or enhancing agent, wherein the first high molecular weight component and the second high molecular weight component are each selected from the group consisting of polyglycans and polypeptides. This stabilized hydrogel matrix may be prepared as bioactive gels, pastes, slurries, cell attachment scaffolds for implantable medical devices, and casting or binding materials suitable for the construction of medical devices. The intrinsic bioactivity of the hydrogel matrix makes it useful as a gel or paste in multiple applications, including as a cell attachment scaffold that promotes wound healing around an implanted device, as gels and pastes for induction of localized vasculogenesis, wound healing, tissue repair, and regeneration, as a wound adhesive, and for tissue bulking. 1. A method for promoting tissue regeneration in mammals comprising the steps of:identifying a specific site in need of tissue regeneration; andadministering a therapeutically effective amount of a cross-linked bioactive hydrogel matrix to the identified site;wherein the bioactive hydrogel matrix comprises a polyglycan covalently cross-linked to a polypeptide and further comprising at least one enhancing agent selected from the group consisting of polar amino acids, intact collagen, divalent cation chelators, and combinations thereof.2. The method of claim 1 , wherein said administering step comprises administering the hydrogel matrix at a vascular terminus claim 1 , wherein the hydrogel matrix is positioned such that the matrix extends laterally from the vascular terminus.3. The method of claim 1 , wherein the hydrogel matrix is cross-linked prior to administration.4. The method of claim 1 , wherein the hydrogel matrix is cross-linked in situ.5. The method of claim 1 , ...

ASSEMBLY AND METHOD FOR CONTROLLING AN AIR INTAKE RUNNER

A subassembly for a valve device for controlling air flow in an intake manifold. The subassembly includes a cartridge including a plurality of compartments having partially open opposing sidewalls, wherein adjacent partially open side walls of adjacent compartments are spaced apart a distance to define a groove therebetween, a plurality of partitions each having a through-hole therein and being disposed in the grooves defined between adjacent partially open side walls of the adjacent compartments. The partitions complete the formation of the opposing side walls of the adjacent compartments and each compartment is alignable with an air intake runner of an intake manifold. 1. A subassembly for a valve device for controlling air flow in an intake manifold , the subassembly comprising:a cartridge including a plurality of compartments having partially open opposing sidewalls, wherein adjacent partially open side walls of adjacent compartments are spaced apart a distance to define a groove therebetween;a plurality of partitions each having a through-hole therein, the partitions being disposed in the grooves defined between adjacent partially open side walls of the adjacent compartments, wherein the partitions complete the formation of the opposing side walls of the adjacent compartments;wherein each compartment of the cartridge is alignable with an air intake runner of an intake manifold.2. The subassembly of claim 1 , further comprising a plurality of flaps each having a through-slot for receiving a shaft claim 1 , wherein each flap is disposed within one of the plurality of compartments.3. The subassembly of claim 1 , further comprising a shaft capable of rotating the flaps claim 1 , the shaft being inserted through the through-holes in the partitions and the through-slot in the flaps.4. The subassembly of claim 3 , wherein each flap includes a connecting portion having an opening with a non-round cross-section and the shaft has a cross-section substantially equivalent ...

HIGH TONNAGE TRAILER COMBINATION, TRAILER COMPONENTS, AND METHOD OF USE

A trailer combination and trailer components are designed to provide dual functionality in terms of hauling a very high tonnage piece of heavy equipment and typical weight pieces of heavy equipment. To accomplish this, a trailer auxiliary is provided to connect to a typical low boy trailer. The trailer auxiliary has mechanisms to provide a bed assembly that is designed to link to the low boy trailer so that the bed assembly and bed of the trailer auxiliary receive the high tonnage piece of equipment. The trailer auxiliary can be equipped with ramps to interface with the trailer and auxiliary to facilitate the loading of the heavy equipment. The trailer combination also includes a hauling vehicle for each of the low boy trailer and auxiliary, with a spacing bar assembly mounted to one of the vehicles to link the vehicles together when hauling the trailer and the auxiliary. 112-. (canceled)13. A method of hauling a high tonnage piece of heavy equipment comprising:providing a low boy trailer having a first tonnage capacity;providing a low boy trailer auxiliary, the low boy trailer auxiliary containing a bed and shovel bed,positioning the shovel bed over a main frame of the low boy trailer and linking the shovel bed to the low boy trailer, andpositioning ramps at ends of each of the low boy trailer and low boy trailer auxiliary and loading the piece of heavy equipment on the low boy trailer and low boy trailer auxiliary,14. The method of claim 13 , wherein the distance between the low boy trailer and low boy trailer auxiliary is sensed during at least the hauling step.15. The method of claim 13 , wherein the ramps are mounted to the auxiliary and moved between a storage position to an operating position at ends of the low boy trailer and auxiliary.16. A trailer combination comprising a low boy trailer and a u-shaped auxiliary claim 13 , the u-shaped auxiliary having sides claim 13 , a rear claim 13 , an axle assembly claim 13 , the combination further comprising means ...

CROSS CONTAMINATION CONTROL SYSTEMS WITH FLUID PRODUCT ID SENSORS

A crossover protection system including a product transport vehicle having a tank compartment for containing a liquid product, a fluid property sensor positioned to contact liquid product stored in the tank compartment, a system controller, and a valve coupled to the tank compartment. The valve regulates a flow of liquid product from the tank compartment and has a normally locked state. The system controller may compare a received transported liquid type signal from the fuel property sensor indicative of the type of liquid product in the tank compartment and compare the type of liquid product to a stored liquid product type. If the two types match, the crossover protection controller transitions the valve to an unlocked state to allow the liquid product to unload from the tank compartment. If the two types do not match, the crossover protection controller will disable the valve from transitioning to the unlocked state. 1. A crossover protection system , comprising:a product transport vehicle comprising a tank compartment for containing a liquid product;a valve coupled to the tank compartment, the valve regulating a flow of liquid product from the tank compartment and having a normally locked state;a tank delivery connector fluidly coupled to a distribution side of the valve; interrogates the tank tag to retrieve a stored liquid type encoded on the tank tag, wherein the stored liquid type is indicative of a type of the liquid product in the distribution tank; and', 'transmits a stored liquid type signal indicative of the stored liquid type and a tank delivery connector ID signal indicative of an identity of the tank delivery connector; and, 'a tank tag reader for interrogating a tank tag coupled to a distribution tank separate from the product transport vehicle, wherein the tank tag reader receive the tank delivery connector ID signal from the tank tag reader;', 'pair the tank delivery connector having the tank delivery connector ID to the system controller;', ' ...

Cross Contamination Control Systems with Fluid Product ID Sensors

A crossover protection system including a product transport vehicle having a tank compartment for containing a liquid product, a fluid property sensor positioned to contact liquid product stored in the tank compartment, a system controller, and a valve coupled to the tank compartment. The valve regulates a flow of liquid product from the tank compartment and has a normally locked state. The system controller may compare a received transported liquid type signal from the fuel property sensor indicative of the type of liquid product in the tank compartment and compare the type of liquid product to a stored liquid product type. If the two types match, the crossover protection controller transitions the valve to an unlocked state to allow the liquid product to unload from the tank compartment. If the two types do not match, the crossover protection controller will disable the valve from transitioning to the unlocked state. 1. A crossover protection system , comprising:a product transport vehicle comprising a tank compartment for containing a liquid product;a valve coupled to the tank compartment, the valve regulating a flow of liquid product from the tank compartment and having a normally locked state;a fluid property sensor positioned to contact the liquid product stored in the tank compartment; and receive a transported fluid property signal from the fluid property sensor, the transported fluid property signal being indicative of at least one of a viscosity, density, dielectric constant, and temperature of the liquid product in the tank compartment;', 'determine a transported liquid type of the liquid product in the tank compartment based on the transported fluid property signal;', 'receive a stored liquid type signal indicative of a stored liquid type of a distribution tank separate from the product transport vehicle;', 'compare the transported liquid type to the stored liquid type;', 'maintain the valve in the normally locked state when the stored liquid type and ...

Tgf- receptor ii isoform, fusion peptide, methods of treatment and methods in vitro

An isoform of the TGF beta receptor II comprising a sequence of about of 80 amino acids and lacking a transmembrane domain. The isoform comprises the amino acid sequence set forth in SEQ ID No. 12. The isoform may have the amino acid sequence set forth in SEQ ID No. 2 or sequences having at least 85% sequence identity to the sequence set forth in SEQ ID No. 2. A fusion peptide is provided comprising an isoform of the TGF beta II receptor fused to a ligand, wherein a vector comprising the fusion peptide is used to treat cancer and/or hepatic fibrosis. An antibody binding the soluble isoform of the TGF beta II receptor is provided. The antibody binds the amino acid sequence shown in SEQ ID No. 12 and is used in in vitro methods.

CHEMICAL MECHANICAL POLISHING PAD, POLISHING LAYER ANALYZER AND METHOD

A chemical mechanical polishing pad, polishing layer analyzer is provided, wherein the analyzer is configured to detect macro inhomogeneities is polymeric sheets and to classify the polymeric sheets as either acceptable or suspect. 1. A chemical mechanical polishing pad , polishing layer analyzer , comprising:{'sub': 'S', 'a magazine for holding a plurality of polymeric sheets, wherein each polymeric sheet (i) comprises: a polymer microelement composite, comprising: a polymer and a plurality of microelements, wherein the plurality of microelements are dispersed in the polymer; and, (ii) has a thickness, T, between a transmission surface and an impinging surface; wherein the transmission surface and the impinging surface are substantially parallel;'}a sequencer;a light source, wherein the light source emits a beam having a luminescence spectrum exhibiting an emission peak wavelength of 460 to 490 nm and a full width at half max, FWHM, of ≦50 nm;a light detector;a digital image data acquisition device coupled to the light detector; and,an image data processing unit coupled to the digital image data acquisition device;{'sub': 'S', 'wherein the sequencer is configured to extract from the magazine and convey the plurality of polymeric sheets, one polymeric sheet at a time, to a position interposed between the light source and the light detector; wherein the beam emitted from the light source is oriented to impinge on the impinging surface; and, wherein the light detector is oriented to detect a transmitted light from the beam that is transmitted through the thickness, T, and out the transmission surface; wherein the light detector is configured to convert an intensity of the transmitted light into an electrical signal; wherein the digital image data acquisition device coupled to the light detector is configured to covert the electrical signal from the light detector into a digital signal; wherein the image data processing unit coupled to the digital image data ...

METHOD OF MANUFACTURING CHEMICAL MECHANICAL POLISHING PADS

A method of manufacturing chemical mechanical polishing pads is provided, wherein an automated inspection system is configured to detect macro inhomogeneities is skived sheets and to classify the skived sheets as either acceptable or suspect; wherein the acceptable skived sheets are further processed to form polishing layers of chemical mechanical polishing pads. 1. A method of manufacturing a chemical mechanical polishing pad having a polishing layer , comprising:providing a cured cake formed from a curable material; wherein the curable material comprises a liquid prepolymer and a plurality of microelements, wherein the plurality of microelements dispersed in the liquid prepolymer;skiving the cured cake to form a plurality of skived sheets; a magazine;', 'a light source, which emits a beam;', 'a light detector;', 'a digital image data acquisition device; and,', 'an image data processing unit;, 'providing an automated inspection system, comprisingloading the plurality of skived sheets into the magazine;{'sub': 'S', 'conveying the plurality of skived sheets, one skived sheet at a time, between the light source and the light detector; wherein the each skived sheet has a thickness, T, between a transmission surface and an impinging surface thereof; wherein the transmission surface and the impinging surface are substantially parallel;'}{'sub': 'S', 'wherein the beam emitted from the light source is oriented to impinge on the impinging surface; and, wherein the light detector is oriented to detect a transmitted light from the beam that is transmitted through the thickness, T, and out the transmission surface;'}wherein the transmitted light has at least one detectable property;wherein the at least one detectable property includes an intensity of the transmitted light;wherein the intensity of the transmitted light is converted into an electrical signal by the light detector;wherein the electrical signal from the light detector is converted into a digital signal by the ...

Polishing layer analyzer and method

A polishing layer analyzer is provided, wherein the analyzer is configured to detect macro inhomogeneities is polymeric sheets and to classify the polymeric sheets as either acceptable or suspect.

High contrast projection screen

The present disclosure describes a front projection system. The front projection system includes a light absorbing layer having an absorbance in a visible range of the electromagnetic spectrum of at least 80% and a light diffusing layer disposed on the light absorbing layer between the light absorbing layer and the projector. The light diffusing layer includes a plurality of metal flakes uniformly distributed in a host material, an average size of the plurality of metal flakes being in a range from about 0.5 microns to about 20 microns, at concentration of in a range from about 3% to about 30% by weight. A plurality of light absorbing particles uniformly distributed in the host material at a concentration of less than about 7% by weight, and a major front surface facing the projector having an average surface roughness in a range from about 0.5 microns to about 10 microns.

ISOFORM OF THE TGF-BETA RECEPTOR II

An isoform of the TGF beta receptor II comprising a sequence of about of 80 amino acids and lacking a transmembrane domain; wherein the isoform is a TGFβ-1 agonist. The isoform comprises the amino acid sequence set forth in SEQ ID No. 12. The isoform may have the amino acid sequence set forth in SEQ ID No. 2 or sequences having at least 85% sequence identity to the sequence set forth in SEQ ID No. 2. 124-. (canceled)25. An isolated isoform of the TGF beta receptor II comprising a sequence of about of 80 amino acids and lacking a transmembrane domain; wherein the isoform is a TGFβ-1 agonist.26. The isoform according to comprising the amino acid sequence set forth in SEQ ID No. 12.27. The isoform according to comprising an amino acid sequence having at least 85% sequence identity to SEQ ID No. 2.28. A polynucleotide encoding the isoform of .29. The polynucleotide according to comprising a nucleotide sequence having at least 90% identity with the nucleotide sequence of SEQ ID No. 1.30. A cell transformed wherein the cell express the isoform of .31. The cell transformed according to comprising the polynucleotide of .32. A fusion peptide comprising an isoform of the TGF beta receptor II fused to a ligand.33. The peptide according to claim 32 , wherein the isoform comprises an amino acid sequence having at least 85% sequence identity to SEQ ID No. 2.34. The peptide according to claim 32 , wherein the ligand is an immunoglobulin Fc portion.35. The peptide according to comprising an amino acid sequence having at least 85% sequence identity to SEQ ID No 6.36. A polynucleotide encoding the peptide of .37. The polynucleotide according to comprising the SEQ ID No. 7.38. A vector comprising at least the polynucleotide of .39. An antibody binding the isoform of .40. The antibody according to claim 39 , wherein the antibody is selected from the group consisting of monoclonal antibodies claim 39 , polyclonal antibodies claim 39 , and fragments thereof.41. The antibody according to ...

Flavor-delivery article

Cross contamination control systems with fluid product id sensors

Adhesives having a microreplicated topography and methods of making and using same

Adhesives having a microreplicated topography are prepared from contacting a microembossed pattern to a layer of adhesive. When an adhesion interface is established between the layer of adhesive and a supporting substrate, the topography of the adhesive surface controls the performance of the adhesion interface. Articles having microreplicated adhesive surfaces are also disclosed that have an advantage of providing microchannels for fluid egress for an effective period of time. Multiple microembossed patterns produce microreplicated adhesive surfaces having both microchannels for fluid egress and pegs for improved adhesive properties.

Coextruded mechanical fastener constructions

A web of material has a plurality of stems extending from at least one side of the web. The web includes a first layer of material having a first side and a second side and a second layer of material. The second layer of material has a first side which faces the first side of the first layer and a second side from which the plurality of stems extend. The first and second layers of material are joined together while they are both molten, before either layer has cooled. The first and second layers of material can be formed of thermoplastic material or melt processable polymeric material. A method of making a web of material includes selecting a first material for a first layer of material and selecting a second material for a second layer of material. The first and second layers of material are melt formed. Then, the first and second layers of material are joined while the layers are in the molten state to form a multiple layer sheet. Next, a plurality of stems are formed on at least the second layer of material. Melt forming can include simultaneously melt forming the first and second layers of material such as by coextrusion.

Process for obtaining products from tar sand

A novel thermal process for recovering hydrocarbon and other products from tar sand. The process includes blending tar sand with a bitumen-rich concentrate while heating the same with a hot, burnt sand. The products are recovered by passing the combined feed through a fluidized bed and selectively controlling the temperature and residence times to obtain predetermined ratios of products. Coked sand residue from the fluidized bed is burned to produce the hot, burnt sand, a portion of which may be recycled to provide heat to the fluidized bed. Coked sand may also be recycled into a known, hot-water, caustic separation process where it synergistically improves the separation efficiency of the hot-water, caustic separation process.

Peptides for inducing cytotoxic T lymphocyte responses to hepattis B virus

Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV polymerase, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens.

Peptides for inducing cytotoxic T lymphocyte responses to hepatitus B virus

Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV polymerase, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens.

Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus

Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV envelope, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens.

Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus

Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV polymerase, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens.

Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus

Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV polymerase, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens.

Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus

Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV envelope, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens.

IMMOBILIZED BIOACTIVE HYDROGEL MATRICES AS SURFACE COATINGS.

Un dispositivo médico recubierto que comprende: un dispositivo médico que tiene una superficie; y una capa de matriz de hidrogel bioactiva que recubre dicha superficie de dicho dispositivo médico y que está inmovilizada sobre la misma, comprendiendo dicha matriz un componente poliglicano y un componente polipéptido, en el que al menos uno de dicho componente poliglicano y dicho componente polipéptido está unido covalentemente a dicha superficie de dicho dispositivo médico o atrapado dentro de dicha superficie de dicho dispositivo médico, en el que la unión covalente se produce por reacción de un grupo reactivo llevado por al menos uno de dicho componente poliglicano y dicho componente polipéptido con un grupo reactivo llevado por dicha superficie de dicho dispositivo médico, y en el que el atrapamiento se produce por deshinchamiento de una superficie de polímero hinchado de dicho dispositivo médico a través del intercambio de la fase líquida con un líquido que comprende al menos uno de dicho componente poliglicano y dicho componente polipéptido. A coated medical device comprising: a medical device that has a surface; and a layer of bioactive hydrogel matrix that covers said surface of said medical device and that is immobilized thereon, said matrix comprising a polyglycan component and a polypeptide component, wherein at least one of said polyglycan component and said polypeptide component is covalently bonded to said surface of said medical device or trapped within said surface of said medical device, wherein covalent bonding occurs by reacting a reactive group carried by at least one of said polyglycan component and said polypeptide component with a group reagent carried by said surface of said medical device, and wherein the entrapment is produced by deflating a swollen polymer surface of said medical device through the exchange of the liquid phase with a liquid comprising at least one of said polyglycan component and said polypeptide component.

Inhibitors of hepatitis c virus infection

Pharmaceutical compounds, compositions, combinations, and methods of treatment of Hepatitis C Virus infection are provided. Compounds of the invention are effective in killing, inhibiting, or blocking viral spread of a Hepatitis C Virus. Methods of preparation and methods of use are also provided.

Assembly and method for controlling an air intake runner

An assembly for controlling an air intake runner of an air intake manifold. The assembly includes a cartridge including a plurality of compartments. Each of the compartments has a plurality of that are joined to define a central opening and an outer perimeter. Adjacent compartments are spaced apart to define a groove between each of the compartments. The assembly also includes bushing carriers that are configured to be snap-fit into one of the grooves of the cartridge. The assembly further includes bushings configured to rotatably fit within the central openings of the bushing carriers. Each of the bushings has an outer rim and an open center. Flaps including a slot and having a shape configured to substantially adjustably seal the central opening are also included and a shaft is included that extends through the slots of the flaps and the open centers of the bushings.

Surge arrester with improved insulative bracket

The insulative support bracket of a surge arrester includes a concentric annular concavity formed at one or both ends of a bolt hole. A washer, when pressed concentrically to the concavity, contacts the insulative bracket only, at least initially, at sur-faces adjacent the outer diameter of the washer. An annular convexity, surrounding the concavity, will mate with the central portion of an external tooth lockwasher to prevent the full penetration of the teeth of the lockwasher into the insulative bracket. The ability of the insulative bracket to withstand the mechanical forces transmitted to the insulative bracket by the washers is thereby enhanced. The con-cavity may be formed either in a surface of the insu-lative bracket or in a surface of the washer.

Gooseneck hitch assembly with u-shaped toe and method of use

A gooseneck hitch assembly adapted for use with a towing vehicle comprises a gooseneck hitch and a u-shaped toe. The u-shaped toe has legs straddling sides of the gooseneck hitch assembly, the legs connected to one or more powered cylinders mounted to the gooseneck assembly. The u-shaped toe also has an enlarged toe end to reduce the bearing pressuring encountered during a hitching operation. The u-shaped toe can include a wear pad mounted to an underside of the toe end to reduce wear during towing use. A wear pad of the bearing plate assembly can further include a beveled surface to accommodate the change in orientation of a free end of the toe during the hitching operation.

IMPROVED MACHINE FOR FUSING EYELETS

UN CHASSIS A DEUX BRAS OPPOSES 14, 16 DONT L'UN PORTE UN OUTIL 26 MONTE FIXE ET DONT L'AUTRE PORTE UN OUTIL 24 ALIGNE AXIALEMENT ET DEPLACABLE PAR RAPPORT AU PREMIER OUTIL DANS UN SENS D'ELOIGNEMENT ET DE RAPPROCHEMENT AVEC UNE FORCE DE SERTISSAGE D'UN OEILLET, MONTE DANS UN TROU D'UNE PLAQUE 112, AJUSTABLE GRACE A UNE VIS 58 AYANT UN BOUTON A COUPLE DE ROTATION AJUSTABLE. A CHASSIS HAS TWO OPPOSED ARMS 14, 16 OF WHICH ONE CARRIES A TOOL 26 FIXED MOUNTED AND THE OTHER OF WHICH CARRIES A TOOL 24 ALIGNED AXIALLY AND MOVABLE IN RELATION TO THE FIRST TOOL IN A DIRECTION OF REMOTE AND APPROXIMATION WITH A FORCE OF CRIMPING OF AN EYE, MOUNTED IN A HOLE OF A PLATE 112, ADJUSTABLE THANKS TO A SCREW 58 HAVING AN ADJUSTABLE ROTATION TORQUE BUTTON.

Fail-safe fluid transfer controller

A fail-safe fluid transfer control apparatus has full redundancy in the response to various inputs such as overfill probe signals, ground detection signals, and the like. Independent microprocessor controllers independently evaluate the inputs and each output control signals to close a respective relay when the inputs indicate that fluid transfer may commence. The relays are arranged in series such that both must be closed for a fluid transfer to commence. The control signals from each controller include a static signal and an alternating signal, both of which must be properly output to close its respective relay. Each controller monitors the state of each relay, and discontinues its control signals if either relay appears to be malfunctioning. Each controller runs an different, independently written firmware program to process the detected inputs to prevent a common firmware error. An optical bypass key replaces conventional mechanical keys and transmits an optically encoded signal to the controller for establishing a bypass condition. A preheating circuit is also provided for providing a dynamic voltage supply to standard thermistor probes which may be encountered.

Material flow rail

An improved material flow rail construction of the type employed to transmit containers or articles from one location to another gravity force. The improved material fow rail comprises a substantially U-shaped channel within which a multiplicity of mounting bolts are attached. Individual bearing assemblies are placed on the mounting bolts. By placing the individual bearing assemblies closely adjacent one another in a longitudinal direction with respect to the support channel, the flow rail has the ability to transmit parts having very small "footprint" areas since a large space between rollers is not presented for parts or components thereof to become caught. By providing a loose fit between the bearing inner races and the supporting mounting bolts, the inner race is permitted to rotate slightly with respect to the mounting bolts thereby presenting new wear surfaces as the flow rail is put into use. Additionally, such loose fit may be provided between the mounting bolts and the support channel to permit the latter to rotate with respect to the former, also presenting new wear surfaces.

Tobacco product and improved process for the expansion of tobacco

NOVEL TOBACCO PRODUCT AND IMPROVED PROCESS FOR THE EXPANSION OF TOBACCO Abstract of the Disclosure A novel tobacco product comprising tobacco containing gaseous carbon dioxide in an amount of at least 1 part of gaseous carbon dioxide per 100 parts of tobacco. The product when heated rapidly is converted to expanded tobacco. An im-proved process for the expansion of tobacco is also provided, which employs carbon dioxide as the expansion agent in a sequence of steps comprising: (1) contacting tobacco with carbon dioxide gas at a pressure of at least 250 psig for a time sufficient to impregnate the tobacco with the carbon. dioxide gas to form a gaseous carbon dioxide-tobacco system (2) releasing the pressure and (3) thereafter subjecting the carbon dioxide-treated tobacco to rapid heating conditions to remove the carbon dioxide and thereby expand the tobacco, The improvement in the above-described process comprising cooling the gaseous carbon dioxide and tobacco system in step (1) to a temperature close to the saturation temperature of carbon dioxide but not lower than -23°C.

Fail-safe fluid transfer controller

Material flow rack

ABSTRACT OF THE DISCLOSURE An improved material flow rail construction of the type employed to transmit containers or articles from one location to another gravity force. The improved material flow rail comprises a substantially U-shaped channel within which a multiplicity of mounting bolts are attached. Individual bearing assemblies are placed on the mounting bolts. By placing the individual bearing assemblies closely adjacent one another in a longitudinal direction with respect to the support channel, the flow rail has the ability to transmit parts having very small "footprint" areas since a large space between rollers is not presented for parts or components thereof to become caught. By providing a loose fit between the bearing inner races and the supporting mounting bolts, the inner race is permitted to rotate slightly with respect to the mounting bolts thereby presenting new wear surface as the flow rail is put into use. Additionally, such loose fit may be provided between the mounting bolts and the support channel to permit the latter to rotate with respect to the former, also presenting new wear surfaces.

Catalytic norbornylation of aromatics

A process is disclosed for the catalytic norbornylation of aromatics comprising the steps of contacting norborene and an aromatic hydrocarbon with an acidic solid catalyst containing a Group IVB metal oxide modified with an oxyanion of a Group VIB metal under norbornylation conditions to evolve a product containing norbornylated aromatics.

Insulating machine and process

Abstract of the Disclosure Apparatus and method for depositing a bed of polymeric insulating foam on a horizontal or sloped surface. The apparatus rolls on the surface being insulated and while it moves forward, lateral bands of insulating foam are sequentially and rapidly deposited by spraying a foamable liquid from a nozzle mounted on a carriage reciprocally moving on a track on the apparatus.

Assembly and method for controlling an air intake runner

A method of modifying an air intake manifold to control air intake runners. The method includes the steps of providing a cartridge including a plurality of compartments, each spaced apart to define a groove therebetween, snap-fitting a bushing carrier having a rotatable bushing into each of the grooves, positioning a flap having a slot over each of the compartments, inserting a shaft through each slot and each bushing thereby rotatably retaining each of the flaps within one of the plurality of compartments, positioning the cartridge over the air intake manifold so that each of the plurality of compartments is substantially axially aligned with one of the air intake runners, and removably connecting the cartridge with the air intake manifold.

Resin transfer molding process

A method for manufacturing, in a resin transfer molding process, a fiber-reinforced polymer object having an exterior surface with first and second portions, the method comprising the steps of providing a first mold with an inner surface, placing dry reinforcement material on the first mold inner surface, providing a second mold including at least one flexible portion with an inner surface having the shape of the object first exterior surface portion, and the second mold also including at least one rigid portion with an inner surface having the shape of the object second exterior surface portion, placing the second mold over the dry reinforcement material to define a space between the first mold inner surface and the inner surfaces of the flexible and rigid portions, reducing the pressure, relative to ambient pressure, in the space between the molds, injecting resin into the space, and curing the resin.

CARDBOARD TRAY WITH STEAMABLE FEET

L'INVENTION CONCERNE UN PLATEAU EN CARTON ETUVABLE MUNI DE PIEDS DESTINES A LE SUPPORTER DANS UNE POSITION DANS LAQUELLE SON FOND DEMEURE AU-DESSUS DE LA SURFACE DE SUPPORT D'UN FOUR OU APPAREIL DE CHAUFFAGE ANALOGUE. SUIVANT L'INVENTION, DEUX COTES OPPOSES 14 DU PLATEAU SONT RELIES A DEUX AUTRES COTES OPPOSES 18 PAR DES RABATS DE FIXATION 34. DEUX COTES OPPOSES 14 DU PLATEAU COMPORTENT DES PARTIES 32 QUI, APRES ERECTION, DEPASSENT SOUS LE FOND 16 DU PLATEAU POUR FORMER DES PIEDS. CHAQUE RABAT DE FIXATION 34 PRESENTE AUSSI UNE PARTIE 40 QUI DEPASSE SOUS LE FOND 16 DU PLATEAU POUR FORMER DES PIEDS SUPPLEMENTAIRES. CES DERNIERS SONT DE PREFERENCE SOLIDAIRES DES PIEDS CITES EN PREMIER LIEU ET PERPENDICULAIRES A CEUX-CI POUR, A LA FOIS, OFFRIR UNE SURFACE DE SUPPORT SUPPLEMENTAIRE ET RENFORCER LES PIEDS CITES EN PREMIER LIEU AFIN D'EVITER LEUR DEFORMATION. THE INVENTION RELATES TO A COOKABLE CARDBOARD TRAY PROVIDED WITH FEET FOR SUPPORTING IT IN A POSITION IN WHICH ITS BOTTOM REMAINS ABOVE THE SUPPORT SURFACE OF AN OVEN OR SIMILAR HEATING APPARATUS. FOLLOWING THE INVENTION, TWO OPPOSITE SIDES 14 OF THE PLATE ARE CONNECTED TO TWO OTHER OPPOSED SIDES 18 BY FIXING FLAPS 34. TWO OPPOSED SIDES 14 OF THE PLATE HAVE PARTS 32 WHICH, AFTER ERECTION, EXCEED BELOW THE BOTTOM 16 OF THE PLATE TO FORM FEET. EACH BINDING FLAP 34 ALSO HAS A PART 40 WHICH EXTENDS UNDER BOTTOM 16 OF THE PLATE TO FORM ADDITIONAL FEET. THESE LATTER ARE PREFERREDLY IN SOLIDARITY OF THE FEET CITED FIRST PLACE AND PERPENDICULAR TO THESE TO BOTH OFFER AN ADDITIONAL SUPPORT SURFACE AND REINFORCE THE FEET CITED FIRST IN ORDER TO AVOID THEIR DEFORMATION.

Tow-Hitch and Gooseneck Attachment for Hauling Vehicles

A gooseneck and tow-hitch attachment includes a gooseneck, a sliding turntable plate assembly, a tow-hitch lifting assembly, a grab hook and a tow-hitch assembly. The sliding plate turntable assembly permits extension or retraction of the gooseneck and swivelable rotation thereof for towing trailers such as low bed trailers. The tow-hitch assembly and tow lifting frame assembly permit using the gooseneck and tow-hitch assembly in a tow truck mode. The tow-hitch assembly also provides a locking function to secure a low bed trailer or like in the gooseneck hitch while providing a lifting force to permit towing thereof. The grab hook functions to properly seat a trailer hitch equipment in the gooseneck and secure the trailer hitch for towing purposes.

Cross contamination control systems with fluid product id sensors

Fail-safe fluid transfer controller

A fail-safe fluid transfer control apparatus has full redundancy in the response to various inputs such as overfill probe signals, ground detection signals, and the like. Independent microprocessor controllers independently evaluate the inputs and each output control signals to close a respective relay when the inputs indicate that fluid transfer may commence. The relays are arranged in series such that both must be closed for a fluid transfer to commence. The control signals from each controller include a static signal and an alternating signal, both of which must be properly output to close its respective relay. Each controller monitors the state of each relay, and discontinues its control signals if either relay appears to be malfunctioning. Each controller runs an different, independently written firmware program to process the detected inputs to prevent a common firmware error. An optical bypass key replaces conventional mechanical keys and transmits an optically encoded signal to the controller for establishing a bypass condition. A preheating circuit is also provided for providing a dynamic voltage supply to standard thermistor probes which may be encountered.

Methods of treating viral diseases with il-18 and il-18 combinations

The present invention relates generally to the use of compositions comprisin g IL-18, also known as interferon-.gamma.-inducing factor (IGIF), and IL-18 in combination with other agents, for the prevention and/or treatment of viral diseases caused by HIV, HSV, HPV, HAV, HBV, and HCV.

Cross contamination control systems with fluid product id sensors

A crossover protection system (10) including a product transport vehicle (15) having a tank compartment (25) for containing a liquid product, a fluid property sensor (130) positioned to contact liquid product stored in the tank compartment (25), a system controller (70), and a valve (45) coupled to the tank compartment (25). The valve (45)regulates a flow of liquid product from the tank compartment (25) and has a normally locked state. The system controller (70) may compare a received transported liquid type signal from the fuel property sensor (130) indicative of the type of liquid product in the tank compartment (25) and compare the type of liquid product to a stored liquid product type. If the two types match, the crossover protection controller (70) transitions the valve (45) to an unlocked state to allow the liquid product to unload from the tank compartment (25). If the two types do not match, the crossover protection controller (70) will disable the valve (45) from transitioning to the unlocked state.

Electrical smoking system for delivering flavors and method for making same

A smoking system (21) is provided in which a replaceable cigarette (23) containing tobacco flavor material is electrically heated by a set of electrical heater elements contained within a lighter (25) to evolve tobacco flavors or other components in vapor or aerosol form for delivery to a smoker. The cigarette (23) and lighter (25) are adapted to provide air flow patterns through the smoking system such that air flows transversely into the cigarette (23). Such patterns improve aerosol and flavor delivery to the smoker and reduce the condensation of residual heater-region vapor/aerosol in the smoking system.

PROCEDURE FOR THE TREATMENT OF TOBACCO AFTER ITS EXPANSION

Linear motion bearing and shafts

A linear motion bearing assembly (40) is provided having a pair of aligned shafts (43, 44) which are fastened together, and a pair of bearings (52, 53) which either roll or slide on the aligned shafts. The shafts may be fastened together along a joint formed on their outer surfaces or they may be fastened together with a spacer (45) disposed between the shafts.

IMPROVED MACHINE FOR FUSING EYELETS

An electronic cigarette system for releasing flavors and a method for making it

Knockdown paper box.

Reordering expanded tobacco by water mist

REORDERING EXPANDED TOBACCO BY WATER MIST Abstract of the Disclosure A process for rapidly and uniformly reordering tobacco material which has been subjected to an expansion treatment is disclosed. The process comprises spraying the tobacco material with a fine water mist characterized by an average droplet size of between about 1 and 120 microns diameter.

Peptides for inducing cytotoxic t lymphocyte responses to hepatitis b virus

Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV envelope, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens.

Peptides for inducing cytotoxic t-lymphocyte responses to hepatitis b virus

Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV nucleocapsid, envelope, polymerase and the transcriptional transactivor X protein, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens. Pharmaceutical compositions and hepatitis B vaccines which comprise the peptides and physiologically acceptable carriers can be employed in conjunction with other HBV vaccines to provide more effective immunity against the disease. Methods for identifying individuals who are particularly susceptible to deve-loping chronic HBV infection and who can be targeted for treatment by the CTL peptides are also provided.

Thermosetting resin transfer molding process

A method of resin transfer molding with a thermoset resin material and including the steps of forming a mold defining a cavity, communicating a hollow sprue with the mold cavity, filling the mold cavity and the sprue with unpolymerized resin and catalyst mixture under pressure, refrigerating the sprue adjacent to the mold cavity so as to delay polymerization of the resin in the sprue to maintain a pressure path through the sprue to the mold cavity during the continued application of pressurized mixture to the sprue, and maintaining the refrigerating of the mixture in the sprue until after at least commencement of polymerization of the resin in the mold cavity to form a molded part.

Surge arrester with draining insulative bracket

A surge arrester comprises a molded insula-tive support bracket for mounting the arrester to a metallic bracket. The insulative bracket includes at least two stringers that form at least one aperture between them. The aperture promotes the draining and drying of the insulative bracket. Baffles formed on the stringers increase the creepage distance across the insulative bracket and increase the rigidity and strength of the insulative bracket.

Peptides for inducing cytotoxic t lymphocyte responses to hepatitis b virus

Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV polymerase, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens.

Electrical smoking system for delivering flavors and method for making same

A smoking system (21) is provided in which a replaceable cigarette (23) containing tobacco flavor material is electrically heated by a set of electrical heater elements contained within a lighter (25) to evolve tobacco flavors or other components in vapor or aerosol form for delivery to a smoker. The cigarette (23) and lighter (25) are adapted to provide air flow patterns through the smoking system such that air flows transversely into the cigarette (23). Such patterns improve aerosol and flavor delivery to the smoker and reduce the condensation of residual heater-region vapor/aerosol in the smoking system.

FOERFARANDE FOER EXPANDERING AV TOBAK

Fuel injection pump control

Fluid-powered toothbrush

Protected magnetic core element

Flavor-delivery article

Methods and apparatus for releasing flavor components from a flavor-generating medium using an electric heating element are provided. A non-combustion flavor-generating article uses electrical energy to power a heating element which heats tobacco or other flavorants. The flavor-generating medium is formed into a packed bed. Energy delivered to the heating element is regulated to maintain the flavor-generating medium at a relatively constant operating temperature to ensure a relatively constant release of flavor.

Viral peptides and their use to inhibit viral infections against viruses of the flaviridae family

The present application is directed to peptides that inhibit infection of a virus from the Flaviviridae family, methods of using these peptides to inhibit viral infections, and pharmaceutical compositions and combinations, as well as articles of manufacture comprising these peptides.

Inhibitors of hepatitis c virus infection

Hepatitis C virus inhibitors of formula (I) and formula (II) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit Hepatitis C Virus and to treat Hepatitis C infections are also disclosed. The compounds are believed to kill, inhibit replication, and/or block viral spread of Hepatitis C virus in a mammal such as a human, through action on a target. The compounds of the invention can be used in the treatment of Hepatitis C virus infections that have developed resistance othe anti-HCV agents, and can be used in combination therapy with other antiviral compounds.

adhesive composite

Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus

Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV nucleocapsid, envelop, polymerase and the transcriptional transactivator X protein, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens. Pharmaceutical compositions and hepatitis B vaccines which comprise the peptides and physiologically acceptable carriers can be employed in conjunction with other HBV vaccinss to provide more effective immunity against the disease. Methods for identifying individuals who are particularly susceptible to developing chronic HBV infection and who can be targeted for treatment by the CTL peptides are also provided.

Immobilized bioactive hydrogel matrices as surface coatings

The present invention is directed to a stabilized bioactive hydrogel matrix coating for substrates, such as medical devices. The invention provides a coated substrate comprising a substrate having a surface, and a bioactive hydrogel matrix layer overlying the surface of the medical device, the hydrogel matrix comprising a first high molecular weight component and a second high molecular weight component, the first and second high molecular weight components each being selected from the group consisting of polyglycans and polypeptides, wherein at least one of the first and second high molecular weight components is immobilized (e.g., by covalent cross-linking) to the surface of the substrate.

Method of expanding impregnated tobacco

Impregnated tobacco is expanded in an expansion operation involving the entrainment of the impregnated tobacco in a heated gas stream under high temperature- short entrainment time conditions resulting in a product of improved quality and enhanced expansion. The expanded gas that contains the tobacco is subjected to a tangential separation operation.

Peptides for inducing cytotoxic t lymphocyte responses to hepatitis b virus

Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV polymerase, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens.

Front loading trailer and method of use

A trailer for hauling heavy equipment includes front end loading assembly that allows hitching and loading, a trailer bed, and a set of rear wheels. Longitudinally aligned support beams from the trailer bed, ends terminating at the front end loading assembly. The front end loading assembly comprises a low profile trailer front end section that uses a box beam positioned between the support beams and a pickup shaft of the assembly. The low profile front end section reduces the height of the front end of the trailer, thereby allowing loading of small equipment, while maintaining its load carrying and transmitting capability for heavy equipment. The trailer can be modular in design with removable ramp and trailer bed side sections.

Expansion of tabacco

Proteinaceous antigens with conformation-independent and conformation-dependent determinants

ABSTRACT A single polypeptide antigen that includes the amino acid residue sequence and epitope of a conformation-independent antigenic determinant and the amino acid residue sequence but lacks the epitope of a conformation-dependent antigenic determinant is disclosed as are methods of its manufacture and use and articles of manufacture using the same. The uses of the pre-S(2) region polypeptide encoded by the hepatitis B virus genome as a T cell proliferating agent and as a potentiator for enhancing the humoral immune response of animals that exhibit a low humoral response to an S region-containing immunogen are also disclosed.

Coextruded mechanical fastener constructions

Fuel injection pump control

A fuel injection pump comprising a housing including a wall having therein a bore, a low pressure fuel chamber communicating with a source of low pressure fuel, and a high pressure fuel chamber having a pressure controlled fuel outlet, an armature structure movably mounted in the housing for movement in a first direction pressurizing the fuel in the high pressure chamber and in an opposite direction, and including a fuel passage communicating between the low pressure fuel chamber and the high pressure fuel chamber and including therein a valve seat, an electrical coil mounted on the housing and operable, when energized, to cause armature structure movement in the first direction, a spring located in the housing and operable, when the coil is deenergized, to cause armature structure movement in the opposite direction, a poppet valve slidable within the fuel passage in the armature structure and relative thereto in response to movement of the armature structure relative to the housing and through a stroke length between a first position permitting flow in the fuel passage from the low pressure fuel chamber to the high pressure fuel chamber, and a second position preventing fuel flow between the high and low pressure fuel chambers, and comprising a head portion located in the high pressure fuel chamber and including a valve surface which is spaced from the valve seat when the poppet valve is in the first position permitting fuel flow from the low pressure fuel chamber to the high pressure fuel chamber, and which is sealingly engaged with the valve seat when the poppet valve is in the second position preventing fuel flow between the high and low pressure fuel chambers, an adjustment member extending in the bore in the housing wall and being engageable with the poppet valve to control the stroke length thereof between the fuel flow permitting and fuel flow preventing positions, and means for displacing the adjustment member relative to the housing end wall to variably ...

Apparatus and method for controlling the transfer of fluid

A fail-safe fluid transfer control circuit includes at least one switch that must be closed to provide power to a pump or valve that enables fluid transfer, at least one controller is provided that monitors the switched state (i.e. open or closed) of each of the switches. If a controller senses that one of the switches is in a closed state when the input conditions warrant it being in an open state, the controller opens the switch, and does not close it until the problem corrects itself or until the problem is corrected by a service person. A bypass control is provided in the form of an optical bypass key which transmits an optically encoded code number to the rack controller, and by which a terminal manager may override certain preventative conditions of the controller. Using the optical bypass key of the present invention, the accessibility of the bypass circuit to a driver is decreased, thus reducing the likelihood of tampering.

Article carrier

Gooseneck hitch assembly with u-shaped toe and method of use

A gooseneck hitch assembly adapted for use with a towing vehicle comprises a gooseneck hitch and a u-shaped toe. The u-shaped toe has legs straddling sides of the gooseneck hitch assembly, the legs connected to one or more powered cylinders mounted to the gooseneck assembly. The u-shaped toe also has an enlarged toe end to reduce the bearing pressuring encountered during a hitching operation. The u-shaped toe can include a wear pad mounted to an underside of the toe end to reduce wear during towing use. A wear pad of the bearing plate assembly can further include a beveled surface to accommodate the change in orientation of a free end of the toe during the hitching operation.

Tobacco product and improved process for the expansion of tobacco

NOVEL TOBACCO PRODUCT AND IMPROVED PROCESS FOR THE EXPANSION OF TOBACCO Abstract of the Disclosure A novel tobacco product comprising tobacco containing gaseous carbon dioxide in an amount of at least 1 part of gaseous carbon dioxide per 100 parts of tobacco. The product when heated rapidly is converted to expanded tobacco. An im-proved process for the expansion of tobacco is also provided, which employs carbon dioxide as the expansion agent in a sequence of steps comprising: (1) contacting tobacco with carbon dioxide gas at a pressure of at least 250 psig for a time sufficient to impregnate the tobacco with the carbon dioxide gas to form a gaseous carbon dioxide-tobacco system (2) releasing the pressure and (3) thereafter subjecting the carbon dioxide-treated tobacco to rapid heating conditions to remove the carbon dioxide and thereby expand the tobacco, The improvement in the above-described process comprising cooling the gaseous carbon dioxide and tobacco system in step (1) to a temperature close to the saturation temperature of carbon dioxide but not lower than -23°C.

Drum storage look-up device

Flavor-delivery article

Methods and apparatus for releasing flavor components from a flavor-generating medium using an electric heating element are provided. A non-combustion flavor-generating article (10) uses electrical energy to power a heating element (14) which heats tobacco or other flavorants (12) in a flavor generating medium. The flavor-generating medium is formed into a packed bed. Energy delivered to the heating element is regulated to maintain the flavor- generating medium at a relatively constant operating temperature to ensure a relatively constant release of flavor and to ensure that release of flavor components is due to heating, rather than burning of the flavor generating medium.

Combination hauling vehicle and low boy trailer and trailer with outrigger assembly

A combination hauling truck and lowboy trailer includes a trailer having a separate power unit and one or more powered axles. An additional powered axle can be added to the hauling truck. The lowboy trailer has outrigger assemblies associated with its rear tires. Tires of the outrigger assemblies move between operative positions for load carrying capability, and retracted positions for maintenance of trailer tires.

Image graphic adhesive system using a non-tacky adhesive

Linear motion bearing and shafts

A linear motion bearing assembly (40) is provided having a pair of aligned shafts (43, 44) which are fastened together, and a pair of bearings (52, 53) which either roll or slide on the aligned shafts. The shafts may be fastened together along a joint formed on their outer surfaces or they may be fastened together with a spacer (45) disposed between the shafts.

High tonnage trailer combination, trailer components, and method of use

A trailer combination and trailer components are designed to provide dual functionality in terms of hauling a very high tonnage piece of heavy equipment and the ability to continue to haul more typical pieces of heavy equipment. To accomplish this task, a trailer auxiliary is provided that is adapted to connect to a typical low boy trailer. The trailer auxiliary is equipped with mechanisms to provide a bed assembly that is designed to link to the low boy trailer so that the bed assembly and bed of the trailer auxiliary receive the high tonnage piece of equipment. The trailer auxiliary can be equipped with ramps to interface with the trailer and auxiliary to facilitate the loading of the heavy equipment. The trailer combination also includes a hauling vehicle for each of the low boy trailer and auxiliary, with a spacing bar assembly mounted to one of the vehicles to link the vehicles together when hauling the trailer and the auxiliary.

Electrical smoking system for delivering flavors and method for making same

BIRD TRAP

Image graphic adhesive system and method for using same

An adhesively mountalbe image using a reusable adhesive surface is provided. The image carrier is removable from the adhesive carrier, and a subsequent image carrier may be releasably bound to the same adhesive carrier. Kits for this system are also provided.

Method and apparatus for non-fluidizing a liquid such as fuel

Medicines to prevent the abnormal mobilization and deposition of calcium phosphate in human and animal tissues

Cross contamination control systems with fluid product ID sensors

A crossover protection system (10) including a product transport vehicle (15) having a tank compartment (25) for containing a liquid product, a fluid property sensor (130) positioned to contact liquid product stored in the tank compartment (25), a system controller (70), and a valve (45) coupled to the tank compartment (25). The valve (45)regulates a flow of liquid product from the tank compartment (25) and has a normally locked state. The system controller (70) may compare a received transported liquid type signal from the fuel property sensor (130) indicative of the type of liquid product in the tank compartment (25) and compare the type of liquid product to a stored liquid product type. If the two types match, the crossover protection controller (70) transitions the valve (45) to an unlocked state to allow the liquid product to unload from the tank compartment (25). If the two types do not match, the crossover protection controller (70) will disable the valve (45) from transitioning to the unlocked state.

Conveyor and conveyor system

Article for dispensing a flavoring.

Image graphic adhesive system and method for using same

An adhesively mountalbe image using a reusable adhesive surface is provided. The image carrier is removable from the adhesive carrier, and a subsequent image carrier may be releasably bound to the same adhesive carrier. Kits for this system are also provided.

Taste / fragrance-giving article

ELECTRIC SMOKING SYSTEM FOR DELIVERING FLAVORS AND PRODUCTION METHOD THEREFOR

Peptides that inhibit viral infections

The present application is directed to peptides that inhibit infection of a virus from the Flaviviridae family, methods of using these peptides to inhibit viral infections, and pharmaceutical compositions and combinations, as well as articles of manufacture comprising these peptides.

Cable coupling

Method of improving chewing gum to reduce alditol bulking agent spots using gum rework material

Spots in manufactured chewing gum caused by sorbitol or other alditol bulking agents are reduced or eliminated by adding trim and a non-aqueous liquid softener to gum base and premixing before the addition of bulking agents and other ingredients.

Cross contamination control systems with fluid product ID sensors

A crossover protection system including a product transport vehicle having a tank compartment for containing a liquid product, a fluid property sensor positioned to contact liquid product stored in the tank compartment, a system controller, and a valve coupled to the tank compartment. The valve regulates a flow of liquid product from the tank compartment and has a normally locked state. The system controller may compare a received transported liquid type signal from the fuel property sensor indicative of the type of liquid product in the tank compartment and compare the type of liquid product to a stored liquid product type. If the two types match, the crossover protection controller transitions the valve to an unlocked state to allow the liquid product to unload from the tank compartment. If the two types do not match, the crossover protection controller will disable the valve from transitioning to the unlocked state.

Lightning arrester

Method of improving chewing gum to reduce alditol bulking agent spots using gum rework material