Methods and systems for cleaning for cyclic nucleation transport (CNX)

Methods are disclosed to create and employ the use of non-vapor, non-condensable gas bubbles inside a process chamber. These non-vapor gas bubbles may be rapidly expanded and compressed in pressure-controlled cycles and can assist in the transport of fluids, particles, and by-products to and from surfaces. The gas bubbles can be generated from dissolved gas to the liquid medium, by mixing two liquids that can react with each other to generate gaseous by-products, or by using a liquid medium that can react with the surface of the object to generate gaseous by-products. The gaseous generation can be used with cyclic nucleation transport (CNX) process, such as vacuum CNX, hyperbaric CNX, or dynamic CNX.

Dynamic chamber for cycle nucleation technology

A dynamic cyclic nucleation transport (D-CNX) process can be used to wet process an object, such as cleaning or etching. In the D-CNX process, the chamber volume is cyclically enlarged and reduced, effectively reducing and increasing the chamber pressure, respectively. During the pressure reduction phase, bubbles can be generated, which can be terminated or travel to the liquid surface during the pressure increment phase. The generation and termination of bubbles can clean or etch the object, even in hard to reach places.

High pressure sperm sorting and flow cytometer methods

Cell sorting methods that improve sorting efficiency and productivity by elevating sorting pressures and incorporate certain steps to help the cells better survive such elevated pressures. In the case of sperm, sorting the steps of standardizing sperm samples, staining sperm samples in a single step, calibrating a flow cytometer to place sperm in the leading edge of droplets, and changing a catch fluid distance may be incorporated individually, or in combination to help sperm better survive the sex sorting process.

Abrasive slicing tool for electronics industry

A bond matrix for metal bonded abrasive tools includes a metal bond system, porosity and an optional filler. Tools according to embodiments of the invention exhibit long tool life, produce an acceptable quality of cut and can have self-dressing properties. The bond matrix can be used, for example, in abrasives tools configured for the electronics industry, such as 1A8 wheels for slicing ball grid arrays (BGAs) and other such slicing operations.

Compositions and methods for treating ocular diseases

The compositions and methods disclosed herein provide for treatments of ocular disorders of the eye, such as ocular surface diseases as well as those associated with inflammation of internal cells and cell layers of the eye. The methods disclosed herein describe methods for treating ocular disorders, particularly dry eye disorders, comprising topically administering to an ocular region of a subject a composition comprising a pharmaceutically effective amount of at least one aldosterone antagonist or salt thereof and a pharmaceutically acceptable carrier. Included is a method for treating dry eye comprising topically administering to an ocular region of a subject a composition comprising spironolactone and hydroxypropyl methylcellulose; and reducing or preventing one or more symptoms or causes of dry eye.

Electrical Outlet Cover with Safety Lock

An outlet cover for an electrical outlet. The outlet cover includes a plate having at least one opening sized and positioned to receive an electrical outlet, a lid hingedly attached to the plate so that the lid can be moved between an open position that allows access to the electrical outlet and a closed position wherein the lid is in a locked position covering the electrical outlet, and a locking assembly having a locking pin. The lid includes a latch which cooperates with the locking pin in order to lock the lid in a closed position or release the lid for opening it for access to the electrical outlet.

User interfaces for managing an account

In some embodiments, exemplary user interfaces for provisioning an electronic device with an account are described. In some embodiments, exemplary user interfaces for providing usage information of an account are described. In some embodiments, exemplary user interfaces for providing visual feedback on a representation of an account are described. In some embodiments, exemplary user interfaces for managing the tracking of a category are described. In some embodiments, exemplary user interfaces for managing a transfer of items are described. In some embodiments, exemplary user interfaces for managing an authentication credential connected with an account are described. In some embodiments, exemplary user interfaces for activating a physical account object are described. In some embodiments, exemplary user interfaces for managing balance transfers are described.

Blood sampling device

A device (302) for sampling and/or analyzing blood or other body fluid of a subject. A housing (306) contains a plurality of lancets (308) and optionally includes test elements (324) to take up a sample of blood, an evaluation system and a display. A complete system that can be handled as a single device, for example in the form of a wristwatch, includes a multiplicity of test elements (324) and lancets (308), which can be brought successively to a working position to perform multiple measurements. A cassette or carrier (320) includes multiple lancets (308) and/or test elements (324), for insertion into the device.

High porosity vitrified superabrasive products and method of preparation

A vitrified superabrasive product includes a superabrasive component and a vitrified bond component in which the superabrasive component is dispersed, wherein the vitrified bond component defines pores occupying greater than about 50% of the total volume of the vitrified superabrasive product. The vitrified superabrasive product can be in the form of a grinding tool, such as a grinding wheel. A superabrasive mixture includes a glass powder, a superabrasive grit, a binder and a silicon carbide. The mixture can be in the form of a green body, which is fired under an atmosphere and pressure, and at a temperature sufficient to form a porous vitrified superabrasive product.

Unidad retenedora que incluye un compensador de grosor de tejido.

Un retenedor para ensamblar compensadores de grosor de tejido a una engrapadora quirúrgica puede comprender un agarre, una primera superficie para soportar un primer compensador de grosor de tejido, una segunda superficie para soportar un segundo compensador de grosor de tejido, y broches para alinear y acoplar el retenedor a la engrapadora quirúrgica; los broches pueden alinear y acoplar el retenedor a un cartucho de grapas del instrumento quirúrgico; los broches pueden alinear al retenedor con un yunque del instrumento quirúrgico; se puede utilizar una herramienta de inserción en combinación con el retenedor para insertar el retenedor a la engrapadora quirúrgica y para empujar los compensadores de grosor de tejido contra el yunque y/o el cartucho de grapas del instrumento quirúrgico.

Low viscosity engine oil compositions

This invention is directed to ultra-low viscosity passenger car engine oil compositions with a kinematic viscosity at 100°C of from 4 to 6 cSt, and comprising in admixture 60 wt% to 90 wt% of a first base oil component, based on the total weight of the composition, the first base oil component consisting of a polyalphaolefm base stock or combination of polyalphaolefm base stocks, each having a kinematic viscosity at 100°C of from 3.2 cSt to 3.8 cSt; and 0.1 wt% to 20 wt% of a second base oil component, based on the total weight of the composition, the second base oil component consisting of a Group II, Group III or Group V base stock, or any combination thereof; wherein the composition comprises from 0 wt% to less than 0.25 wt% viscosity index improver, on a solid polymer basis; wherein the composition has a kinematic viscosity at 100°C of from 4 to 6 cSt, a Noack volatility of less than 15% as determined by ASTM D5800, a CCS viscosity of less than 3500 cP at -35°C as determined by ASTM D5293, and an HTHS viscosity of less than 2.6 mPa-s at 150°C as determined by ASTM D4683.

Container closure

Disposable container closures of low gas and vapor permeability, high-impact resistant, cleanly combustible thermoplastics fusable to the rim of container openings to seal the same but readily manually opened by integral tab positioned to commence tears along score lines promoting and utilizing the unexpected relatively low resistance of the otherwise tough materials to continued tearing once a tear is started.

User interfaces for managing an account

In some embodiments, exemplary user interfaces for provisioning an electronic device with an account are described. In some embodiments, exemplary user interfaces for providing usage information of an account are described. In some embodiments, exemplary user interfaces for providing visual feedback on a representation of an account are described. In some embodiments, exemplary user interfaces for managing the tracking of a category are described. In some embodiments, exemplary user interfaces for managing a transfer of items are described. In some embodiments, exemplary user interfaces for managing an authentication credential connected with an account are described. In some embodiments, exemplary user interfaces for activating a physical account object are described. In some embodiments, exemplary user interfaces for managing balance transfers are described.

Protein screeing methods

Blood sampling device with lancet damping system

A blood sampling device is provided with a housing, a lancet assembly, a lancet holder disposed in the housing for supporting the lancet assembly, the lancet holder being movable in a lancing direction between a cocked position and a puncture position, a drive spring for forcing the lancet holder from the cocked position to the puncture position, and a mechanism for damping movement of the lancet holder during travel of the lancet holder from the puncture position to an intermediate position between the puncture position and the cocked position. The damping mechanism may be provided in the form of a non-planar surface, such as a corrugated surface, disposed on the lancet holder and a damping member which makes contact with the non-planar surface during movement of the lancet holder.

Methods and compositions for the manufacture of replication incompetent adenovirus

The present invention relates to complementing cell lines for the production of replication incompetent viruses, which significantly reduce or eliminate the presence of replication competent viruses. Methods to make and use the complementing cell lines are also provided, as are nucleic acid molecules, polynucleotides, and vectors for making the cell lines. In particular, the present invention relates to complementing cell lines for the production of replication incompetent adenoviruses (Ad), which significantly reduce or eliminate the presence of replication competent Ad (RCA) and can serve for the large scale production of infectious replication incompetent adenovirus particles that may be used for the treatment of human patients as for example in gene therapy. The present invention further relates to an assay for detecting the presence of replication competent virus particles, in particular RCA, in a stock of infectious replication incompetent virus particles, in particular replication incompetent adenovirus particles, which employs a real time quantitative PCR assay with a sensitivity level to detect one replication competent virus particle per ≥ 109 replication incompetent virus particles.

Blood sampling device

A device ( 302 ) for sampling and/or analyzing blood or other body fluid of a subject. A housing ( 306 ) contains a plurality of lancets ( 308 ) and optionally includes test elements ( 324 ) to take up a sample of blood, an evaluation system and a display. A complete system that can be handled as a single device, for example in the form of a wristwatch, includes a multiplicity of test elements ( 324 ) and lancets ( 308 ), which can be brought successively to a working position to perform multiple measurements. A cassette or carrier ( 320 ) includes multiple lancets ( 308 ) and/or test elements ( 324 ), for insertion into the device.

Blood sampling device

A device (302) for sampling and/or analyzing blood or other body fluid of a subject. A housing (306) contains a plurality of lancets (308) and optionally includes test elements (324) to take up a sample of blood, an evaluation system and a display. A complete system that can be handled as a single device, for example in the form of a wristwatch, includes a multiplicity of test elements (324) and lancets (308), which can be brought successively to a working position to perform multiple measurements. A cassette or carrier (320) includes multiple lancets (308) and/or test elements (324), for insertion into the device.

Blood sampling device

Blood analyzer device where the test media (10) and needle (8) are arranged on a carrier which turns relative to the main body (4) and can be inserted into it. Through rotation, the media and needle are brought into their individual working positions (32, 34).

Blood sampling device

A device for sampling and/or analyzing blood or other body fluid of a subject. A housing contains a plurality of lancets and optionally includes test elements to take up a sample of blood, an evaluation system and a display. A complete system that can be handled as a single device, for example in the form of a wristwatch, includes a multiplicity of test elements and lancets, which can be brought successively to a working position to perform multiple measurements. A cassette or carrier includes multiple lancets and/or test elements, for insertion into the device.

Blood sampling device

A device for sampling and/or analyzing blood or other body fluid of a subject. A housing contains a plurality of lancets and optionally includes test elements to take up a sample of blood, an evaluation system and a display. A complete system that can be handled as a single device, for example in the form of a wristwatch, includes a multiplicity of test elements and lancets, which can be brought successively to a working position to perform multiple measurements. A cassette or carrier includes multiple lancets and/or test elements, for insertion into the device.

Blood analyzer and pricking device for use in blood analysis

The invention relates to a blood analyzer (2) that comprises a device (6) for taking a blood sample, equipped with pricking elements (8, 114, 122, 232), and test means (10) for receiving a minimum amount of blood. Said test means (10) and the pricking elements (8, 114, 122, 232) are disposed on a support (50) which can be rotated with respect to the housing base (4) and can be inserted in the analyzer along with said support. The test means (10) and the pricking elements (8, 114, 122, 232) can be brought into working positions (32, 34) relative to the housing base that are different from one another by rotating the support (50).

Blood analyzer and pricking device for use in blood analysis

Blood analyzer and pricking device for use in blood analysis

The invention relates to a blood analyzer (2) that comprises a device (6) for taking a blood sample, equipped with pricking elements (8, 114, 122, 232), and test means (10) for receiving a minimum amount of blood. Said test means (10) and the pricking elements (8, 114, 122, 232) are disposed on a support (50) which can be rotated with respect to the housing base (4) and can be inserted in the analyzer along with said support. The test means (10) and the pricking elements (8, 114, 122, 232) can be brought into working positions (32, 34) relative to the housing base that are different from one another by rotating the support (50).

BLOOD ANALYZER AND PUNCHING DEVICE FOR USE IN BLOOD ANALYSIS.

Analizador (2) de sangre con un cuerpo (4) de carcasa, con un dispositivo (6) de extracción de sangre que presenta un elemento (8, 114, 122, 232) de pinchado, con un medio (10) de prueba para el alojamiento de una cantidad mínima de sangre, con un dispositivo (12) de valoración que comprende un sistema electrónico de valoración y con un dispositivo (14) de visualización que forman un sistema completo que puede manejarse como un único aparato, presentando el cuerpo (4) de carcasa una posición (22) de pinchado asociada a la posición (34) de trabajo del elemento (8, 114, 122, 232) de pinchado para la colocación de una superficie cutánea de un usuario, y una posición (30) de alimentación configurada en otro punto del cuerpo de carcasa para alimentar una cantidad mínima de sangre que sale de la superficie cutánea previamente pinchada sobre un medio (10) de prueba, pudiendo emplearse en el aparato una pluralidad de medios (10) de prueba y elementos (8, 114, 122, 232) de pinchado que pueden llevarse a una posición (30, 34) de trabajo para realizar varias mediciones sucesivas, con lo que, al colocar un elemento (8, 114, 122, 232) de pinchado en su posición (34) de trabajo, el elemento de pinchado puede pincharse en la superficie cutánea de un usuario colocada en la posición (22) de pinchado y la sangre que sale de la superficie cutánea puede proporcionarse a un medio (10) de prueba mediante la colocación de la superficie cutánea en la posición (30) de alimentación, encontrándose dicho medio de prueba en una posición (32) de trabajo del medio de prueba, estando dispuestos los medios (10) de prueba y los elementos (8, 114, 122, 232) de pinchado sobre un soporte (50) giratorio frente al cuerpo (4) de carcasa y pudiendo utilizarse con éste en el aparato, y porque mediante del soporte (50), los medios (10) de prueba y los elementos (8, 114, 122, 232) de pinchado pueden llevarse a diferentes posiciones (32, 34) de trabajo entre sí con respecto al cuerpo de carcasa.

Lancing device and multi-lancet cartridge

A lancing device and a removable and replaceable multi-lancet cartridge for use in connection therewith are disclosed. The multi-lancet cartridge is advanced through sequential lancets, and anti-reverse features prevent reverse advancement of the cartridge. Interlocks are provided to prevent double-cocking the device, to reduce the likelihood of jamming of the mechanism. Improved trigger mechanisms and depth control mechanisms are provided.

Cap displacement mechanism for lancing device and multi-lancet cartridge

A medical lancing device including a replaceable multi-lancet cartridge (10). The lancing device includes an advancing mechanism that advances lancets within the cartridge into an active position, separates a protective cap (28) from the active lancet (20), and energize a drive mechanism of the lancing device. A cap displacement mechanism moves the separated cap (28) out of the travel path of the active lancet (20). In a first example embodiment, the cap displacement mechanism includes a cantilevered spring arm (50) that displaces the detached cap of the active lancet. In a second example embodiment, the cap displacement mechanism includes a spring-biased cam-driven plunger (232) that displaces the detached cap of the active lancet. Then an activation mechanism releases the energized active lancet to traverse the unobstructed lancing stroke path to pierce the subject's skin at a desired lancing site.

Blood sampling device

A sampling device ( 20 ) having a housing ( 24 ) with a lancet cartridge ( 22 ) mounted therein. The lancets ( 26 ) of the lancet cartridge ( 22 ) are interconnected by a flexible web ( 28 ). The lancet cartridge ( 22 ) is not positively engaged within the housing ( 24 ) and can be easily removed. The housing ( 24 ) has an opening ( 42 ) with an adjacent flexible or compressible fin ( 60 ) for dampening the motion of the lancet ( 26 ). The lancet cartridge ( 22 ) has at least one lancet ( 26 ) with an endcap, and the housing has a cap-removal mechanism ( 74 ) for separating the endcap from the housing ( 24 ). Anti-tampering features prevent opening of the device when the lancet cartridge ( 22 ) is oriented with a lancet ( 26 ) in a firing position.

Multi-lancet device with sterility cap repositioning mechanism

A lancing device has a carousel of lancets removably received in a housing. In exemplary embodiments, the lancing device includes a sterility cap positioning mechanism that removes sterility caps from the lancets for actuation and afterwards replaces the sterility caps onto the lancets. Preferably, the lancing device includes a lancet advancing mechanism that automatically advances sequential lancets of the lancet carousel for charging and actuating, and a drive mechanism for actuating the lancets. Also provided are replacement lancet carousels, which include a cylindrical carrier with axial openings and a plurality of the lancets axially oriented in the openings.

Blood sampling device

A lancing device for sampling blood or other body fluid of a subject includes a reusable housing and a disposable cassette. The cassette contains a plurality of lancets held in a storage plane. An active lancet is moved transversely from the storage plane into a firing plane, into engagement with a drive mechanism for actuation to lance the subject's skin. After actuation, the used lancet is returned to the storage plane. Each lancet includes a protective endcap that is removed from the lancet just prior to use and then is replaced onto the lancet after use.

Blood sampling device

A sampling device having a lancing apparatus, and optionally a detector and a meter. The lancing apparatus includes a replaceable cartridge of lancets, each lancet having an independent arming and drive mechanism enabling non-sequential and/or simultaneous firing of lancets. A lancet retainer independently associated with each lancet is movable to uncover an opening through which the lancet tip passes, and to release the lancet for activation. The lancets can be actuated in any order, and multiple lancets can be simultaneously actuated, if desired.

Lancing device

Blood sampling device

A sampling device (20) having a housing (24) with a lancet cartridge (22) mounted therein. The lancets (26) of the lancet cartridge (22) are interconnected by a flexible web (28). The lancet cartridge (22) is not positively engaged within the housing (24) and can be easily removed. The housing (24) has an opening (42) with an adjacent flexible or compressible fin (60) for dampening the motion of the lancet (26). The lancet cartridge (22) has at least one lancet (26) with an endcap, and the housing has a cap-removal mechanism (74) for separating the endcap from the housing (24). Anti-tampering features prevent opening of the device when the lancet cartridge (22) is oriented with a lancet (26) in a firing position.

Blood analyzer and pricking device for use in blood analysis

Blood sampling device

A device (302) for sampling and/or analyzing blood or other body fluid of a subject. A housing (306) contains a plurality of lancets (308) and optionally includes test elements (324) to take up a sample of blood, an evaluation system and a display. A complete system that can be handled as a single device, for example in the form of a wristwatch, includes a multiplicity of test elements (324) and lancets (308), which can be brought successively to a working position to perform multiple measurements. A cassette or carrier (320) includes multiple lancets (308) and/or test elements (324), for insertion into the device.

Blood sampling device

A device (302) for sampling and/or analyzing blood or other body fluid of a subject. A housing (306) contains a plurality of lancets (308) and optionally includes test elements (324) to take up a sample of blood, an evaluation system and a display. A complete system that can be handled as a single device, for example in the form of a wristwatch, includes a multiplicity of test elements (324) and lancets (308), which can be brought successively to a working position to perform multiple measurements. A cassette or carrier (320) includes multiple lancets (308) and/or test elements (324), for insertion into the device.

Blood analyzer and pricking device for use in blood analysis

Die Erfindung betrifft ein Blutanalysegerät (2) mit einer ein Stechelemente (8, 114, 122, 232) aufweisenden Blutentnahmevorrichtung (6), mit Testmittel (10) für die Aufnahme einer Minimalmenge von Blut, wobei die Testmittel (10) und die Stechelement (8, 114, 122, 232) auf einem gegenüber dem Gehäusekörper (4) drehbaren Träger (50) angeordnet und mit diesem in das Gerät einsetzbar sind und durch Drehen des Trägers (50) die Testmittel (10) und die Stechelemente (8, 114, 122, 232) in voneinander verschiedene Arbeitspositionen (32, 34) bezüglich des Gehäusekörpers bringbar sind.

Cap displacement mechanism for lancing device and multi-lancet cartridge

A medical lancing device including a replaceable multi-lancet cartridge (10). The lancing device includes an advancing mechanism that advances lancets within the cartridge into an active position, separates a protective cap (28) from the active lancet (20), and energize a drive mechanism of the lancing device. A cap displacement mechanism moves the separated cap (28) out of the travel path of the active lancet (20). In a first example embodiment, the cap displacement mechanism includes a cantilevered spring arm (50) that displaces the detached cap of the active lancet. In a second example embodiment, the cap displacement mechanism includes a spring-biased cam-driven plunger (232) that displaces the detached cap of the active lancet. Then an activation mechanism releases the energized active lancet to traverse the unobstructed lancing stroke path to pierce the subject's skin at a desired lancing site.

Blood sampling device

A lancing device for sampling blood or other body fluid of a subject includes a reusable housing and a disposable cassette (150). An active lancet is moved transversely from the storage plane into a firing plane, into engagement with a drive mechanism (130) for actuation to lance the subject's skin. After actuation, the used lancet is returned to the storage plane. Each lancet includes a protective endcap (183) that is removed from the lancet just prior to use and then is replaced onto the lancet after use.

Lancing device with multi-lancet magazine

A lancing device and replaceable multi-lancet cartridge for use in sampling of body fluids. Sequential lancets of the cartridge are translationally retracted along a storage path, pivoted into an angularly offset firing path, and translationally propelled by a drive mechanism to lance the subject's skin.

Blood sampling device

A sampling device having a lancing apparatus, and optionally a detector and a meter. The lancing apparatus includes a replaceable cartridge of lancets, each lancet having an independent arming and drive mechanism enabling non-sequential and/or simultaneous firing of lancets. A lancet retainer independently associated with each lancet is movable to uncover an opening through which the lancet tip passes, and to release the lancet for activation. The lancets can be actuated in any order, and multiple lancets can be simultaneously actuated, if desired.

Methods for tagging dna-encoded libraries

Apparatus for lifting objects by suction and releasing them by gas pressure

An apparatus includes a lifting device having a gas-attachment end and a lifting end, two pins each attachable to the gas-attachment end of the lifting device, and a gas-supply coupler for connecting a gas supply to the lifting device. Each pin has a longitudinal bore extending therethrough and an extending portion which extends beyond the gas-attachment end of the lifting device when the pins are attached thereto. One of the pins has an exterior annular notch on the extending portion. The gas-supply coupler is connectable to the two pins and has a locking element which releasably locks into the annular notch on the pin having the annular notch. The lifting device, the two pins, and the gas-supply coupler together have two passages leading from the gas-supply coupler, through the longitudinal bores of the two pins and to the lifting end of the lifting device. One passage is designed such that, when gas flows therethrough toward the lifting end, suction is created at the lifting end. The other passage is designed such that, when gas flows therethrough toward the lifting end, gas is expelled at the lifting end.

SEALING UNIT.

PISTON JOINT

La réalisation de joints de piston pour des cylindres pneumatiques nécessite l'utilisation de matériaux de haute qualité à faible coefficient de friction. Pour minimiser le coût de fabrication du joint de piston 1, le matériau de haute qualité coûteux n'est utilisé qu'aux endroits où il est effectivement nécessaire, à savoir aux surfaces d'étanchéité et de glissement 7a, 7b. On économise ainsi une quantité importante du matériau coûteux, et les rebuts de fabrication n'influent que peu sur les coûts de fabrication. Le joint de piston convient pour l'incorporation dans des cylindres pneumatiques pour l'industrie alimentaire, où les fluides hydrauliques sont exclus pour des motifs de sécurité et/ou de santé. The production of piston seals for pneumatic cylinders requires the use of high quality materials with a low coefficient of friction. To minimize the cost of manufacturing the piston seal 1, the expensive high quality material is only used where it is actually needed, namely at the sealing and sliding surfaces 7a, 7b. This saves a significant amount of expensive material, and manufacturing scrap has little impact on manufacturing costs. The piston seal is suitable for incorporation into pneumatic cylinders for the food industry, where hydraulic fluids are excluded for reasons of safety and / or health.

Suction device with a device for preventing infection.

Mechanical seal unit

A seal unit for a pump shaft has a sliding ring seal (6) and a counter ring (3) mounted in a clip-on-sleeve 25. In use the sleeve is mounted onto the pump shaft and lies between a seal area (I) and a holder area (III). The seal area (I) is formed from a material eg. rubber of greater elasticity than the sleeve eg metal. The holder area is also of rubber and engages the sliding ring seal (6) to hold the two parts together. The seal area (I) and the holder area (III) are of a one-piece design. <IMAGE>

Cyclic diol-derived blocked mercaptofunctional silane compositions

Microbiological oxidation to lactones

Ultrasonic surgical forceps device

(57)【要約】 【課題】 超音波外科用鉗子凝固装置が、装置の鉗子機 構と付随する超音波エンドエフェクターとの協同によ り、組織を切断、凝固そして挟むように形成される。 【解決手段】 便利で、しかも効率的な装置の使用は、 装置のハウジングに関して選択的に回転させるために、 中に超音波ウエイブガイドを有する装置の延長部ならび に付随する超音波駆動ユニット含む装置の超音波部品を 形成することによりなされる。この装置のハウジング は、好ましくは付随する部品を回転可能に支持するため の支持体壁および部材の配置を含み、ハウジングはさら に、超音波駆動ユニットが装置のウエイブガイドの操作 的連結のために装置のハウジング内に受け入れられた 時、その整列を容易にする特徴を含む。

11, 15-dioxygenated progesterones

Prosthesis for abdominal aortic aneurysm repair

The device of the present invention comprises a bifurcated graft fabricated from expanded PTFE (ePTFE). The inventive device is double walled so that following insertion into an aneurysm, fluid can be injected between the walls to expand the device thereby opening the inner tubular graft for receiving blood flow and locking the device into place in the aorta. The injected fluid may polymerize so that the device is permanently held in its expanded form. One embodiment of the device is fabricated with packets or channels. After the device is delivered and expanded additional stiffening struts can be inserted into these pockets. In this way the basic device can be furled and tightly compressed for delivery (something not possible with a stent containing device). After the device is expanded, a stent-like structure can be inserted endovascularly giving the strength and resiliency of a stent-containing prosthesis.

Multifunction abrasive tool with hybrid bond

Abrasive tools and techniques are disclosed that can cut hard, brittle materials to relatively precise dimensions. The tools, which can include a hybrid bond of metal or metal alloy and a resin matrix together with fine abrasive grits, can be employed, for example, in mirror finish cutting applications, thereby enabling '1X' or 'single-pass' multi-function abrasive processes. The specific selection of resin and metal or metal alloy types is such that the tool is sufficiently brittle for the purpose of manufacture and durability, but ductile enough to withstand the grinding and handling stresses (an exemplary hybrid bond includes bronze and polyimide). Numerous tool types and applications will be apparent in light of this disclosure, including abrasive products for electronic device manufacturing such as thin 1A8 blades (single blade or multi-blade configuration).

Compounds for use in treatment of mucositis

Process for the preparation of streptovaricin

Apparatus and method for encoding and decoding signals

TIRE AND COMPONENTS COMPOSITIONS CONTAINING SILENTED NUCLEAR POLYSULFETS

AUTO INJECTOR WITH EXTENDABLE NEEDLE PROTECTION COVER

Reduction of average-to-minimum power ratio in communications signals

This invention, generally speaking, modifies pulse amplitude modulated signals to reduce the ratio of average power to minimum power. The signal is modified in such a manner that the signal quality remains acceptable. The signal quality is described in terms of the Power Spectral Density (PSD) and the Error Vector Magnitude (EVM).

11alpha-hydroxy-a-norprogesterone

Cyclic compounds and methods of making and using the same

The present invention provides compounds, or pharmaceutically acceptable salts thereof, for inhibiting the growth of a microbe; treating a mammal having a microbial infection, mucositis, an ophthalmic infection, an otic infection, a cancer, or a Mycobacterium infection; inhibiting the growth of a Mycobacterium species; modulating an immune response in a mammal; or antagonizing unfractionated heparin, low molecular weight heparin, or a heparin/low molecular weight heparin derivative.

Pdgf receptor beta binding polypeptides

Fluid ejection cartridge and method

SYRINGE DRUM FOR LIOFILIZATION RECONSTITUTION AND ADMINISTRATION

Methods and devices for treating fractured and/or diseased bone

Pressure relieving device

Zinc borate of low hydration and method of preparing same

Hydrazone substituted penems

There is disclosed 2-(oximinoalkylthio) and 2-(hydrazono-alkylthio)-penems, their pharmaceutically acceptable salts and esters, their use as antibacterials, and a process for making them. The compounds have the general formula wherein R 10 is -OR 2 or and R is R 1 , R 2 , R 3 , R 4 , R 12 and R 13 are as defined in the specification.

Multifunction abrasive tool with hybrid bond

Abrasive tools and techniques are disclosed that can cut hard, brittle materials to relatively precise dimensions. The tools, which can include a hybrid bond of metal or metal alloy and a resin matrix together with fine abrasive grits, can be employed, for example, in mirror finish cutting applications, thereby enabling '1X' or 'single-pass' multi-function abrasive processes. The specific selection of resin and metal or metal alloy types is such that the tool is sufficiently brittle for the purpose of manufacture and durability, but ductile enough to withstand the grinding and handling stresses (an exemplary hybrid bond includes bronze and polyimide). Numerous tool types and applications will be apparent in light of this disclosure, including abrasive products for electronic device manufacturing such as thin 1A8 blades (single blade or multi-blade configuration).

SILADO CYCLE CORE POLYESULPHETS, THEIR PREPARATION AND USE IN THE FIELD OF ELASTOMIC COMPOSITIONS

The surface of treatment of nanoparticles to control interfacial properties and method of manufacture

A surface treated particle comprising a plurality of inorganic, metallic, semi-metallic, and/or metallic oxide particles and a star-graft copolymer with looped and/or linear polymeric structure on a star-graft copolymer, obtainable by a heterogeneous polymerization reaction in the particle surface proximity, encapsulating at least a portion of said particles and a method for making the same. The surface treatment comprises: Si (w, x, y, z), where: w, x, y, and z are mole percent tetrafunctional, trifunctional, difunctional, and monofunctional monomeric units, respectively; w, x, y, and z are about 0-50, 0-50, 5 - 99, and 0-5, respectively; w is tetraethylorthosilicate; x is selected from the group consisting of Ϝ-glycidoxypropyltrimethoxysilane, Ϝ-methacryloxypropyltrimethoxysilane, methyltrimethoxysilane, n-propyltrimethoxysilane, isobutyltrimethoxysilane, n-hexyltrimethoxysilane, n-octyltrimethoxysilane, n-octadecyltrimethoxysilane, phenyltrimethoxysilane, 3-(trimethoxysilyl)propylsuccinic anhydride, heptadecafluorotrimethoxysilane, 3-isocyanatopropyltrimethoxysilane, 2-(diphenylphosphino)ethyltrimethoxysilane, 3-aminopropyltrimethoxysilane, 3-mercaptopropyltrimethoxysilane, n-(trimethoxysilylpropyl)EDTA, pentafluorophenylpropyltrimethoxysilane, trifluoropropyltrimethoxysilane, and the triethoxy-containing counterparts of these monomers; y is selected from the group consisting of dicyclohexyldimethoxysilane, diethyldiethoxysilane, dimethyldichlorosilane, dimethyldiethoxysilane, dimethyldimethoxysilane, diphenyldiethoxysilane, diphenyldimethoxysilane, di-n-hexyldichlorosilane, n-hexylmethyldichlorosilane, methyldodecyldiethoxysilane, n-octylmethyldimethoxysilane, and the diethoxy-containing counterparts of these monomers; and z is selected form the group consisting of n-octadecyldimethylmethoxysilane, triethylsilanol, trimethylethoxysilane, trimethylmethoxysilane, and the ethoxy-containing counterparts of these monomers. Product(s) per se, defined as surface ...

SYSTEM FOR MULTIPLEXED TRANSMISSION OF AUXILIARY DATA FOR VIDEO TABLETS.

La presente invención se refiere a un sistema de transmisión de señal detelevisión, que comprende un multiplexor para combinar una señal de datosde video comprimida y una o más señales de datos auxiliares, para formaruna señal multiplejada (multiplexada) para transmisión en un canal deancho de banda fijo. El multiplexor se controla para variar la relación delos componentes que comprende la señal multiplejada (multiplexada), paraasegurar calidad de imagen satisfactoria reproducible, en respuesta a losdatos de señal de video comprimidos recibidos. Los datos de señal de videocomprimidos pueden ser sometidos a memoria intermedia antes de combinacióncon los datos auxiliares, en ese caso el multiplexor también se controlaadicionalmente para variar la relación de los componentes que comprende laseñal multiplejada (multiplexada) para mantener la carga de la memoriaintermedia a un nivel aceptable.

Modular cargo carrier assembly

A cargo carrier assembly (10) includes a platform (12) adapted to nestingly support a cargo container (14). The cargo container includes projections (58) extending outwardly for matingly engaging aligned slots (22) in the platform. The cargo container bottom periphery defines an exterior dimension that is less than the exterior dimension defined by the cargo container side wall periphery, whereby the container side wall exterior surface and the platform side wall exterior surface are substantially coplanar when the cargo container is nested on the platform.

Substrate cleaning components and methods in a plating system

Systems for cleaning electroplating system components may include an electroplating apparatus including a plating bath vessel. The electroplating apparatus may include a rinsing frame extending above the plating bath vessel. The rinsing frame may include a rim extending circumferentially about an upper surface of the plating bath vessel and defining a rinsing channel between the rim and the upper surface of the plating bath vessel. The electroplating apparatus may also include a rinsing assembly including a splash guard that is translatable from a recessed first position to a second position extending at least partially across an access to the plating bath vessel. The rinsing assembly may also include a fluid nozzle extending from the rinsing frame.

Method for the preparation of benzyloxyphenoxy pentanoates

A method of producing benzoyloxyphenoxy pentanoic acid esters comprising the steps of: (a) reacting a compound of the formula ##STR1## wherein A is as defined with a compound of the formula ##STR2## wherein X is as defined, in the presence of a base selected from carbonate salts of alkaline earth or alkali metals, a catalyst and a ketonic solvent to produce a 3-(4-benzyloxyphenoxy)-2-butanone; and (b) reacting said 3-(4-benzyloxyphenoxy)-2-butanone with a dialkyl carbonate of the formula (RO) 2 CO, wherein R is an alkyl group having from 1 to 4 carbon atoms, in the presence of a suitable base and an organic solvent, to form alkyl 4-(4-benzyloxyphenoxy)-3-oxopentanoate.

2-(fluoroalkylthio)substituted penems, processes for preparing them, and pharmaceutical compositions containing them

A B S T R A C T Compounds are disclosed having the formula (1) in which the stereochemistry is 5R,6S,8R or 5R,6R,8S, A represents a fluoroalkyl group, straight chain or branched chain, with 1 to 3 fluorine atoms on the came carbon atom which is separated from the 2-S atom by at least one carbon atom, and R is hydrogen, a pharmaceutically acceptable cation or a metabolisable ester group. The compounds have antibacterial activity.

Direct acting reverse osmosis water purifier valves

A direct acting reverse osmosis water purifier valve is disclosed. The purifier valve has a single diaphragm valve responsive to the pure water pressure to shut off the tap water inlet when the pure water pressure approaches the tap water line pressure, indicating that the pure water storage tank is full. This shut-off valve, in conjunction with the venting of the tap water line to drain within the system upon shut-off, results in a self actuating effect causing the shut-off valve to close in a positive manner once closing is initiated. Similarly, a direct acting pilot valve is used to control the squeeze water control valve to respond as desired to the pure water pressure to control the squeeze water for the purification and dispensing cycles. Functioning of the valve is very similar to that of the prior art though with a much simplified and more reliable structure.

Modular cargo carrier assembly

Communication among partitioned devices

A computing device having partitions, and a method of communicating between partitions, are disclosed wherein at least one partition comprises: at least one register substantially always accessible to other partitions and capable of defining an address area; at least one address area that may be accessible to other partitions and is capable of being defined by the at least one register; and address areas other than the at least one accessible address area that are not accessible to other partitions. A method of processing interrupts comprising receiving an interrupt, assessing the origin of the interrupt, accepting, rejecting, or further assessing the interrupt, depending on its origin, when further assessing the interrupt, accepting or rejecting the interrupt depending on its contents, and forwarding accepted interrupts but not rejected interrupts to a target processor, and a device carrying out that method are also disclosed.

System for accommodating withdrawal of liquid from a bulk supply.

Suction device with a device for preventing infection.

Silated cyclic core polysulfides, their preparation and use in filld elastomer compositions

Secure credential storage and retrieval

Techniques are disclosed relating to securely receiving and storing credentials. In some embodiments, a computing device includes an application executable to supply a credential to an external system. A secure circuit of the computing device is configured to send, to a credential storage, a request for the credential, the request including a first certificate identifying a first public key and a stipulation to perform a user authentication before permitting use of a first private key corresponding to the first public key. The secure circuit receives, from the credential storage, the credential encrypted using the first public key and, based on the stipulation, performs the user authentication prior to decrypting the credential and supplying it to the application. In some embodiments, the secure circuit receives the first certificate by providing information about hardware included in the computing device to a hardware verification service.

Syringes and syringe systems for selectively dispensing controlled amounts of a therapeutic substance

A syringe may include various forms of a releasable stop adapted to selectively limit the travel of the syringe plunger within the syringe barrel such that a first amount of therapeutic substance may be discharged from the syringe while a residual supply of the therapeutic substance remains in the syringe. Movement of the plunger is permitted to displace the residual supply of fluid from the barrel. Syringes according to the invention find particular application as diluent syringes in a wet/dry drug delivery syringe system having two cooperating syringe barrels in which the residual supply of diluent in the diluent syringe may be used to flush additional and otherwise wasted drug from a drug syringe barrel.

2-(heterocycloalkylthio)penems

This invention relates to 2-(heterocycloalkylthio)penems wherein the nitrogen of the heterocyclic ring is connected to the alkyl group, and to their use as antibacterial agents.

Low-powered remote sensor and telephone line transmitter

A data transmitter unit (22) for transmitting data over conventional telephone lines (26) from a remote location (24) to a central location (28). The data transmitter unit (22) derives its operational power supply from the telephone lines (26) to which it is interconnected, thereby doing away with the requirement for a separate power supply. The transmitter unit (22) includes ring detect circuitry (46) for detecting a ring signal on the telephone line (26). The ring detect circuitry (46) cooperates with the stand by power supply (38) charged by a charging circuit (36) to energize a logic module (44) and analog converter circuitry (40, 42) which is interconnected to sensors (30, 32). The logic module (44) controls operation of a tone generator (48) which transmits frequency signals representative of the input received from the sensors (30, 32) over the telephone lines (20, 26) to a central location (28).

Injection site.

Lancing device and method of sample collection

A lancing device (10) and method for self-collecting a sample of body fluid by penetrating a body tissue at a sampling site. The invention includes a housing geometry (16) configured for ease of use at different sampling sites on the body, even by persons having reduced dexterity and/or poor vision. Depth of penetration is selectively controlled by adjusting the stroke range of a spring-driven lancet carrier (38). A pressure applicator is included for stimulating flow of the body fluid. A transparent portion permits observation of the sampling site.

Leak-proof water processing unit

The present invention comprises a reverse osmosis water purifying unit in which all the components of the unit are housed in a protective enclosure. In one form the protective enclosure is a water tight protective enclosure which itself is vented to the drain. The only external connections to the enclosure are by means of sealed bulkhead fittings. These fittings are used to connect the water purifying unit to a main water supply line, a dispensing faucet and a drain line. A fourth fitting communicates the inside of the enclosure directly to the drain, or alternatively, the inside of the enclosure is coupled to the drain line internal to the enclosure. The enclosure protects the components of the water purifying system from exposure to outside abuse and damage, and also act to contain and direct and leakage that does occur to prevent any spillage from escaping from the enclosure. Use of a drain line larger than the water supply line allows containment of a leak of any size within a relatively low pressure enclosure. In another form, the protective cause is not sealed, though upon opening, provides easy access to the internal components while providing a water proof service tray to eliminate spillage of water released upon disassembly of the water purifier for servicing.

Improved toroidal transformer and machines and methods for making toroidal transformers

A toroidal electrical transformer having a low voltage coil, a high voltage coil and an annular magnetic core in which the low voltage and high voltage coils are each continuous and form and arcuate elongated passage therethrough. The annular magnetic core is wound in place in said arcuate elongated passage substantially from a continuous strip of magnetic material resulting in a toroidal transformer with continuous windings and a continuous wound core. Various components and sub-assemblies are also disclosed along with various apparatus and methods for producing such toroidal electrical transformers, its components and its _[ sub-assemblies.

Multi-layered, helically wound paper tube

Syringe systems for lyophilized drugs and methods for making the same

A syringe system requires a decreased vertical travel for sealing during a lyophilization process and therefore provides for increased utilization of space in a lyophilization chamber. The syringe system is provided with a sterility maintenance sleeve including a stopper affixed thereto for sealingly engaging the syringe barrel to define a drug chamber. The sterility maintenance sleeve is provided with a venting passage to permit egress of vapor from the drug chamber during lyophilization. A plug cap cooperating with the sterility maintenance sleeve includes an occluding tip whigh is adapted to occupy the venting passage and seal the drug chamber after lyophilization. The plug cap is provided with a support structure in the form of flexible fins for supporting the plug cap in a venting position in which the occluding tip is removed from the venting passage to permit egress of drug solution vapor from the drug chamber during lyophilization. After lyophilization, the plug cap is moved into a sealing position in which the drug chamber is sealed against contamination.

Lancing device and method of sample collection

A lancing device and method for self-collecting a sample of body fluid by penetrating a body tissue at a sampling site. The invention includes a housing geometry configured for ease of use at different sampling sites on the body, even by persons having reduced dexterity and/or poor vision. Depth of penetration is selectively controlled by adjusting the stroke range of a spring-driven lancet carrier. A pressure applicator is included for stimulating flow of the body fluid. A transparent portion permits observation of the sampling site.

High porosity abrasive articles and methods of manufacturing same

An abrasive article includes a polymer matrix and abrasive grains dispersed in the polymer matrix, wherein the abrasive article has a void volume of at least 50%. The polymer matrix is polymerized from a monomer including at least one double bond.

Precisely guided lancet

A lancet having one or more portions of the shank of the lancet blade exposed of direct engagement with cooperating portion(s) of the lancet carrier of a lancing device. This direct engagement of the lancet blade with the lancet carrier provides more precise positional control of the location of the lancing site by eliminating the effect that any variation in the position of the lancet blade within the lancet body would otherwise have on the positioning of the lancet tip. Tolerance stack-up is thereby reduced and accuracy is improved, reducing the necessary sample size and minimizing pain resulting from the lancing operation.

Method for decarboxylation of amino acids via imine formation

The present application provides methods for decarboxylation of amino acids via imine formation with a catalyst under pressurized and superheated conditions in either a microwave or oil bath.

Door-check.

Insertion devices and method of use

This invention relates to devices, such as cannulas or needles, which are us ed for inserting expandable structures, such as medical balloons, into interior regions of a human or animal body, as well as methods for their use. In various embodiments, insertion devices described herein are capable of flari ng at their tip to ease insertion and removal of expandable structures and redu ce the risk of domaging such expandable structures during their insertion, inflation and removal. In other embodiments, insertion devices described herein are capable of directionally guiding and/or inhibiting expansion of a n expandable structure within an interior region of an animal or human body to create optimally placed cavities for repair, augmentation and/or treatment o f fractured and/or diseased bone.

Hinge

Method of making magnetic toroids