23-08-2012 дата публикации
Номер: US20120214899A1
Принадлежит:
The present invention provides a method for producing a silicone hydrogel having a high water content. The method comprises the following steps: 1. A method for producing a silicone hydrogel having a high water content comprising the following steps:(a) polymerizing a monomer mixture to form the silicone hydrogel, wherein the monomer mixture comprises at least one silicon-containing monomer and at least One ionic monomer; and(b) placing the silicone hydrogel in an alkaline solution for at least 20 minutes,wherein the alkaline solution has a pH not less than 7.5 and the ionic monomer is present in an amount not less than 0.7 wt % based on the total dry weight of the silicone hydrogel.2. The method according to claim 1 , wherein the pH of the alkaline solution is in a range of 7.5 to 11.3. The method according to claim 2 , wherein the pH of the alkaline solution is in a range of 8 to 10.4. The method according to claim 1 , wherein the alkaline solution is prepared from a base selected from the group consisting of LiOH claim 1 , NaOH claim 1 , KOH claim 1 , Mg(OH) claim 1 , Ca(OH) claim 1 , NHOH claim 1 , NaCO claim 1 , KCO claim 1 , MgCO claim 1 , CaCO claim 1 , (NH)CO claim 1 , BaCO claim 1 , NaHCO claim 1 , KHCO claim 1 , CaO claim 1 , BaO claim 1 , NaNH claim 1 , KNH claim 1 , Mg(NH) claim 1 , Ca(NH) claim 1 , Zn(NH) claim 1 , and Al(NH) claim 1 , and a combination thereof.5. The method according to claim 4 , wherein the alkaline solution is NaOH or NaHCOsolution.6. The method according to claim 1 , wherein the silicone hydrogel is placed in the alkaline solution for 30 to 480 minutes.7. The method according to claim 1 , wherein the water content of the silicone hydrogel is not less than 50%.8. The method according to claim 1 , wherein the ionic monomer is present in an amount of 0.7 to 10 wt % based on the total dry weight of the silicone hydrogel.9. The method according to claim 8 , wherein the ionic monomer is present in an amount of 1 to 3 wt % based on the ...
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