Intraatrial ventricular assist device

A medical device comprises a pump adapted to fit within an atrium of a heart, said pump comprising an inlet and an outlet. The device further comprises a flexible outflow conduit coupled to said outlet. A method of assisting ventricular function of a heart of a patient comprises: a) inserting a continuous flow pump having an inlet and an outlet into the heart via a subclavian or jugular vein; b) attaching the outlet of the continuous flow pump to an atrial septum, wherein the inlet of the continuous flow pump is directed into a heart atrium; c) attaching the distal end of the outflow conduit to an artery; and d) operating the pump at a volumetric rate ranging from about 2 L/min to about 3 L/min.

Devices and methods for fistula formation

Described here are devices and methods for forming a fistula between two vessels. In some instances, the fistula may be formed between a proximal ulnar artery and a deep ulnar vein. The fistula may be formed using an electrode, and may be formed with a first catheter placed in a first blood vessel and a second catheter placed in a second blood vessel. In some instances, access to the proximal ulnar artery may be achieved through a brachial artery, and access to the deep ulnar vein may be achieved through a brachial vein.

Cardiac treatment system

An assembly for providing localized pressure to a region of a patient's heart to improve heart functioning, including: (a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and (b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart.

Method and apparatus for treating a patient by intentionally occluding a blood vessel, including method and apparatus for inducing weight loss in a patient by intentionally occluding the celiac artery

A method for inducing weight loss in a patient, the method comprising: intentionally occluding a blood vessel so as to create hypoperfusion in a gastrointestinal organ serviced by the blood vessel, whereby to interfere with normal gastrointestinal function and thereby induce weight loss in a patient.

Cardiac treatment system and method

Devices and methods for providing localized pressure to a region of a patient's heart to improve heart functioning, including: (a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and (b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart.

Atraumatic Occlusion Balloons and Skirts, and Methods of Use Thereof

One aspect of the present invention relates to catheters that can be placed in or around bodily conduits to occlude or widen a biological lumen without imparting significant trauma to the lumen. In certain embodiments, the invention particularly relates to the use of a polymer composition which can be made to gel upon insertion into said balloon or skirt. In certain embodiments, the inflating viscous polymer composition is a liquid at room temperature and a gel at mammalian physiological temperature. In certain embodiments, the inflating viscous polymer composition comprises an optionally purified inverse thermosensitive polymer. 1. A method of occluding , widening or stenting a lumen in a mammal , comprising the steps of:positioning a catheter into said mammalian lumen at a location, wherein said catheter comprises an elongated shaft having an inflation lumen and a balloon connected to a distal end of the elongated shaft so that an interior chamber of the balloon is in fluid communication with the inflation lumen; and wherein an open proximal end of the balloon is in fluid communication with said mammalian lumen;deploying said balloon, via said inflation lumen, with a composition comprising at least one polymer by introducing the composition in a manner sufficient to expand the balloon, wherein said composition gels partially or completely in said balloon.2. The method of claim 1 , wherein said method is substantially atraumatic to said mammalian lumen.3. The method of claim 1 , wherein said mammalian lumen is temporarily occluded.4. The method of claim 1 , wherein said mammalian lumen is permanently occluded.5. The method of claim 1 , wherein said at least one polymer is at least one purified inverse thermo sensitive polymer.6. The method of claim 5 , wherein said purified inverse thermosensitive polymer has a polydispersity index from about 1.5 to about 1.0.7. The method of claim 5 , wherein said purified inverse thermosensitive polymer has a polydispersity index ...

CARDIAC TREATMENT SYSTEM AND METHOD

Devices and methods for providing localized pressure to a region of a patient's heart to improve heart functioning, including: (a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and (b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart. 1. (canceled)2. A method of treating heart valve dysfunction , the method comprising:positioning a cardiac support device (CSD) around a ventricular portion of a heart;allowing a time period to pass so that fibrotic encapsulation of the CSD on the heart can occur; andafter the time period has passed, adjusting the CSD to treat valvular dysfunction.3. The method of claim 2 , further comprising putting contrast agent solution into contact with epicardial tissue of the heart and using radiographic imaging to visualize an atrial-ventricular (AV) groove of the heart.4. The method of claim 3 , wherein the CSD includes a plurality of radiopaque markers on an open distal end of the CSD claim 3 , and wherein said positioning includes advancing the open distal end of the CSD over an apex of the heart and using radiographic imaging to position the plurality of radiopaque markers on the open distal of the CSD in the AV groove.5. The method of claim 2 , wherein the CSD includes an inflatable bladder claim 2 , and wherein said positioning includes aligning the inflatable bladder with a targeted surface region on a wall of the heart.6. The method of claim 5 , wherein the targeted surface region is adjacent a mitral valve or a tricuspid valve.7. The method of claim 5 , wherein the CSD includes an inflation tube in fluid ...

Devices and methods for forming a fistula

Described here are devices, systems and methods for forming a fistula between two blood vessels. Generally, the systems may comprise a first catheter which may comprise a fistula-forming element. The fistula-forming element may comprise one or more electrodes, mechanical cutting elements, laser sources, or combinations thereof, and may be used to assist in fistula formation. In some instances, a system may comprise a second catheter, which may comprise a fistula-forming element. One or more of the catheters may comprise one or more markers, magnetic alignment elements, and/or one shape-changing element.

Non-axisymmetric aortic valve devices

The present disclosure provides aortic valve prosthetic devices that are constructed in a non-axisymmetric shape, or are expandable to a non-axisymmetric shape for improved results in the repair of defective aortic valves. The devices can be surgically implanted, or they can be implanted percutaneously through an insertion catheter. The expandable devices can be self-expanding or expanded by an inflatable balloon to a non-axisymmetric cross-section geometry.

Cardiac treatment system and method

Devices and methods for providing localized pressure to a region of a patient's heart to improve heart functioning, including: (a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and (b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart.

METHODS AND KITS FOR TREATING LACERATIONS AND PUNCTURE WOUNDS USING INVERSE THERMOSENSITIVE POLYMERS

In certain embodiments, the present invention relates to methods and kits for treating wounds, comprising the step of introducing into said wound a composition comprising at least one optionally purified inverse thermosensitive polymer, wherein said at least one optionally purified inverse thermosensitive polymer forms a gel in said wound, thereby temporarily occluding said wound. In certain embodiments, the present invention relates to the aforementioned method wherein a wound to a blood vessel or a segment of the GI tract is occluded, thereby preventing exsanguination and/or septicemia. In other embodiments, the inventive methods and kits described herein may be used to ameliorate (e.g., fill) temporarily a defect in a biological lumen, thereby strengthening said defect, preventing rupture of, or maintaining, improving or optimizing fluid flow through said lumen.

Device and System for Insertion of Penetrating Member

A system, device and method for insertion of a penetrating member into tissue is disclosed, which may be handheld and automated. A detector obtains data regarding subdermal locations of tissue structures, including cavities such as blood vessels. A processor calculates the distance between a preselected target point below the tissue surface, such as within a blood vessel, and the tissue surface, and adjustment data for vertical, angular and extension adjustment of the penetrating member. Vertical, angular and extension actuators carry out the adjustments in real-time as calculated and directed by the processor. Changes in the location of the target point result in automatic recalculation and adjustment by the processor and various actuators. A vibrational actuator induces vibration to the penetrating member during insertion, overcome tissue deformation and vein rolling. A guidewire may be inserted through or by the device, for dilator and catheter insertion once the penetrating member is removed. 2. The system as recited in claim 1 , wherein said data representative of said location of said tissue includes image data.3. The system as recited in claim 2 , further comprising a display presenting said image data of said location of said tissue.4. The system as recited in claim 3 , wherein said display further presents a visual representation of said preselected target point within said tissue.5. The system as recited in claim 4 , wherein said display is interactive and said visual representation of said preselected target point within said tissue can be moved around on said display.7. The system as recited in claim 6 , wherein said detector utilizes sound waves to obtain said data representative of said location of said cavity within said tissue.8. The system as recited in claim 7 , wherein said detector utilizes ultrasound to obtain said data representative of said location of said cavity within said tissue.9. A device for inserting a penetrating member into tissue ...

Apparatus and method for the ligation of tissue

A novel catheter-based system that ligates the left atrial appendage (LAA) on the outside of the heart, preferably using a combination of catheters and/or instruments, e.g., a guide catheter inserted into the interior of the left atrial appendage that may assist in locating the left atrial appendage and/or assist in the optimal placement of a ligature or constricting element on the outside of the appendage, and a ligating catheter and/or instrument outside the heart in the pericardial space to set the ligature or constricting element at the neck of the left atrial appendage.

CARDIAC TREATMENT SYSTEM AND METHOD

Devices and methods for providing localized pressure to a region of a patient's heart to improve heart functioning, including: (a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and (b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart. 1an implant body comprising a mesh material that is formed into a generally tubular configuration, the implant body comprising a leading end portion defining an open leading end and a trailing end portion defining an open trailing end of a diameter that is less than a diameter of the open leading end, the trailing end portion having a length configured to extend proximal of the apex of the heart when the leading end portion is positioned in an atrial-ventricular groove of the heart; anda fillable bladder mounted to the implant body and positioned relative to the open leading end such that, when the leading end portion is positioned in the atrial-ventricular groove, the fillable bladder is positionable on an exterior of a heart wall.. A cardiac implant for implantation around an exterior of a heart, the implant comprising: This application is a continuation of U.S. patent application Ser. No. 14/053,587 filed Oct. 14, 2013, which claims priority to U.S. Provisional Patent Application No. 61/713,351 filed on Oct. 12, 2012, the contents of which are fully incorporated herein by reference.The present disclosure relates to medical devices for treating heart diseases and valvular dysfunction, including valvular regurgitation.Various compression-style systems currently exist for treating heart diseases and ...

Intra-operative heart size measuring tool

A heart size measuring tool includes a tubular body, a flexible measuring cord having length indicia, a measuring cord support mechanism movable between retracted and extended states with respect to the body, and an actuating mechanism to move the measuring cord support mechanism. When in the retracted state the measuring cord support mechanism is positioned within the tubular body with the measuring cord in a collapsed position. When the measuring cord support mechanism is in the extended state the measuring cord extends around a portion of a heart to be measured. A scale on the body can be used in connection with the indicia on the measurement cord to provide a reading of the heart size.

Intra-operative heart size measuring tool

A heart size measuring tool includes a tubular body, a flexible measuring cord having length indicia, a measuring cord support mechanism movable between retracted and extended states with respect to the body, and an actuating mechanism to move the measuring cord support mechanism. When in the retracted state the measuring cord support mechanism is positioned within the tubular body with the measuring cord in a collapsed position. When the measuring cord support mechanism is in the extended state the measuring cord extends around a portion of a heart to be measured. A scale on the body can be used in connection with the indicia on the measurement cord to provide a reading of the heart size.

CARDIAC TREATMENT SYSTEM

An assembly for providing localized pressure to a region of a patient's heart to improve heart functioning, including: (a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and (b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart. 1(a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and(b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface positioned adjacent to the heart such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart.. An assembly for providing localized pressure to a region of a patient's heart to improve heart functioning, comprising: This application is a continuation of U.S. application Ser. No. 14/053,261 filed on Oct. 14, 2013, which claims priority to U.S. Provisional Application Ser. No. 61/713,351 filed on Oct. 12, 2012, the contents of this aforementioned application being fully incorporated herein by reference.The present disclosure relates to medical devices for treating heart diseases and valvular dysfunction, including valvular regurgitation.Various compression-style systems currently exist for treating heart diseases and conditions such as congestive heart disease and valvular dysfunction. These systems typically involve either: (a) jackets that ...

System and method for attaching a vessel in a vascular environment

An apparatus is provided in one example embodiment and includes a body section having an upper surface, a lower surface, and an inner edge circumferentially arranged around at least a portion of an open area. The apparatus also includes a tool extending from the body section into the open area for holding a graft vessel. The lower surface of the body section opposes a receiving vessel when the tool is positioned to transfer the graft vessel to the receiving vessel, such that the graft vessel is axially accessible through the open area to be attached to the receiving vessel. In more specific embodiments, the body section has first and second opposing ends defining a gap sized to permit the vessel to pass through.

Intra-Operative Heart Size Measuring Tool

A heart size measuring tool includes a tubular body, a flexible measuring cord having length indicia, a measuring cord support mechanism movable between retracted and extended states with respect to the body, and an actuating mechanism to move the measuring cord support mechanism. When in the retracted state the measuring cord support mechanism is positioned within the tubular body with the measuring cord in a collapsed position. When the measuring cord support mechanism is in the extended state the measuring cord extends around a portion of a heart to be measured. A scale on the body can be used in connection with the indicia on the measurement cord to provide a reading of the heart size. 1inserting into a patient's body through a minimally invasive access port a heart measurement tool having a measurement device movable between extended and retracted states;positioning a distal end portion of the heart measurement tool adjacent to an apex of the patient's heart while the measurement device is in the retracted state;actuating the measurement tool to move the measurement device to the extended state around at least a portion of the patient's heart;determining the heart size measurement using the measurement device in the extended state;and actuating the measurement tool to move the measurement device to the retracted state; withdrawing the measurement tool from the patient's body.. A method for measuring a size of a patient's heart in connection with the implantation of a therapeutic device surrounding at least a portion of the heart, including: This application is a continuation of U.S. patent application Ser. No. 14/698,689 filed Apr. 28, 2015, which is a continuation of U.S. application Ser. No. 13/261,173, filed on Jun. 29, 2012 (now U.S. Pat. No. 9,044,169 Issued Jun. 2, 2015), which is a United States national stage entry of International Application no. PCT/US2010/028830 filed Mar. 26, 2010 and entitled “Intra-Operative Heart Sizing Tool,” which claims ...

Apparatus for replacing a cardiac valve

A prosthetic heart valve in combination with a delivery assembly that includes a first elongate component that is movably disposed to a second elongate component. The delivery assembly has a temporary valve location relative to the delivery assembly to which the prosthetic heart valve can be releasably mounted in position and a spaced implantation location relative to the delivery assembly to which the prosthetic heart valve can also be releasably mounted in position. The prosthetic heart valve and delivery assembly combination is configurable with movement of the first elongate component relative to the second elongate component from a delivery state with the prosthetic heart valve mounted in the temporary location to an implantation state with the prosthetic heart valve repositioned from the temporary, location to the implantation location so that the prosthetic heart valve can subsequently be deployed from the implantation location.

Aortic Valve Devices

The present disclosure provides aortic valve prosthetic devices that are constructed in an elliptical shape, or are expandable to an elliptical shape for improved results in the repair of defective aortic valves. The devices can be surgically implanted, or they can be implanted percutaneously through an insertion catheter. The expandable devices can be self-expanding or expanded by an inflatable balloon to an elliptical cross section geometry. 1. A medical device for implantation into an aortic valve of a mammal , the device comprising an elliptical cross sectional shape in a plane perpendicular to the direction of blood flow through the aortic valve.2. The device of claim 1 , further described as comprising a base and commissure support members attached to the base claim 1 , wherein the members flare outwardly from the base at an angle of from 8°-12° from a line perpendicular to the outer edge of the elliptical cross-section.3. The device of claim 2 , wherein the members extend away from the base at an outward angle of about 10° from a line perpendicular to the outer edge of the elliptical cross-section.4. The device of claim 1 , wherein the ratio of the major axis of the ellipse to the minor axis of the ellipse is between about 1.2 and 1.8.5. The device of claim 4 , wherein the ratio of the major axis of the ellipse to the minor axis of the ellipse is about 1.5.6. The device of claim 1 , wherein the length of the major axis of the elliptical cross section is between about 10 millimeters and about 35 millimeters.7. The device of claim 1 , wherein the length of the minor axis of the elliptical cross section is between about 8 millimeters and about 25 millimeters.8. The device of claim 1 , wherein the device comprises a plastic claim 1 , a polymer claim 1 , a metal claim 1 , a thermoplastic claim 1 , a resin claim 1 , or combinations thereof.9. The device of claim 8 , wherein the device comprises metal.10. The device of claim 9 , wherein the intra-annular mounting ...

Non-Axisymmetric Aortic Valve Devices

The present disclosure provides aortic valve prosthetic devices that are constructed in a non-axisymmetric shape, or are expandable to a non-axisymmetric shape for improved results in the repair of defective aortic valves. The devices can be surgically implanted, or they can be implanted percutaneously through an insertion catheter. The expandable devices can be self-expanding or expanded by an inflatable balloon to a non-axisymmetric cross-section geometry.

Apparatus for Replacing a Cardiac Valve

A delivery assembly for delivering a prosthetic heart valve can include a first elongate component and a second elongate component. The delivery assembly includes a temporary valve location to which the prosthetic heart valve can be releasably mounted and an implantation location to which the prosthetic heart valve can also be releasably mounted. The delivery assembly can move from a delivery state with the prosthetic heart valve mounted to the temporary location to an implantation state with the prosthetic heart valve repositioned from the temporary location to the implantation location. The prosthetic heart valve can subsequently be deployed from the implantation location. The position of the prosthetic heart valve relative to the first elongate component at the temporary location is different than a position of the prosthetic heart valve relative to the first elongate component at the implantation location. 119-. (canceled)20. A prosthetic heart valve in combination with a delivery assembly , the delivery assembly comprising:a first elongate component that is movably disposed to a second elongate component, wherein the first elongate component is configured to deploy the prosthetic heart valve at a fixation site,the delivery assembly having a temporary valve location to which the prosthetic heart valve can be releasably mounted and an implantation location to which the prosthetic heart valve can also be releasably mounted,the prosthetic heart valve and delivery assembly combination being configurable with movement of the first elongate component relative to the second elongate component from a delivery state with the prosthetic heart valve mounted to the temporary location to an implantation state with the prosthetic heart valve repositioned from the temporary location to the implantation location so that the prosthetic heart valve can subsequently be deployed from the implantation location, wherein a position of the prosthetic heart valve relative to the first ...

Method and apparatus for treating a patient by intentionally occluding a blood vessel, including method and apparatus for inducing weight loss in a patient by intentionally occluding the celiac artery

A method for inducing weight loss in a patient, the method comprising: intentionally occluding a blood vessel so as to create hypoperfusion in a gastrointestinal organ serviced by the blood vessel, whereby to interfere with normal gastrointestinal function and thereby induce weight loss in a patient.

METHODS AND DEVICES TO CLEAR OBSTRUCTIONS FROM MEDICAL TUBES

A device for clearing obstructions from a medical tube, such as a chest tube, is disclosed in various embodiments. The device features a clearance member in the form of a loop. The loop desirably has a diameter that substantially corresponds to the inner diameter of the medical tube. Also desirably, the loop presents a substantially unobstructed pathway therethrough for the flow of material from a location in the medical tube distal to the loop to a location in the medical tube proximal to the loop regardless whether the clearance member is being translated or is at rest in the medical tube. Methods of utilizing such a device are also disclosed. 1. A method of clearing obstructions from a medical tube , comprising coupling a guide tube in fluid communication with a medical tube thereby defining a common passageway through the respective tubes comprising a sterile field , wherein an elongate guide member is entirely disposed within said common passageway , and actuating said guide member without compromising the sterile field to correspondingly translate a clearance member attached to or formed with said guide member in said medical tube.2. The method of claim 1 , said guide member being actuated from outside said sterile field.3. The method of claim 1 , said guide member being actuated from outside said sterile field through a wall of said guide tube.4. The method of claim 1 , said guide tube further comprising a shuttle that is coupled to said guide member claim 1 , said shuttle being actuated from outside said sterile field to correspondingly actuate said guide member and thereby translate said clearance member in the medical tube.5. The method of claim 1 , said guide member being actuated via a shuttle that is translated axially relative to a longitudinal axis of said guide member.6. The method of claim 1 , said guide member comprising a guide wire.7. The method of claim 6 , said clearance member comprising a wire loop formed from or attached to a terminal ...

Methods And Kits For Treating Lacerations And Puncture Wounds Using Inverse Thermosensitive Polymers

In certain embodiments, the present invention relates to methods and kits for treating wounds, comprising the step of introducing into said wound a composition comprising at least one optionally purified inverse thermosensitive polymer, wherein said at least one optionally purified inverse thermosensitive polymer forms a gel in said wound, thereby temporarily occluding said wound. In certain embodiments, the present invention relates to the aforementioned method wherein a wound to a blood vessel or a segment of the GI tract is occluded, thereby preventing exsanguination and/or septicemia. In other embodiments, the inventive methods and kits described herein may be used to ameliorate (e.g., fill) temporarily a defect in a biological lumen, thereby strengthening said defect, preventing rupture of, or maintaining, improving or optimizing fluid flow through said lumen. 1. A method of temporarily occluding a bleeding internal wound cavity in a mammal , comprising:directly introducing into said bleeding internal wound cavity a composition comprising at least one purified inverse thermosensitive polymer, andforming a gel in said bleeding internal wound cavity sufficient to temporarily occlude said bleeding internal wound cavity.2. The method of claim 1 , wherein said at least one purified inverse thermosensitive polymer is selected from the group consisting of purified poloxamers and purified poloxamines.3. The method of claim 1 , wherein said at least one purified inverse thermosensitive polymer is selected from the group consisting of purified poloxamer 407 claim 1 , purified poloxamer 338 claim 1 , purified poloxamer 118 claim 1 , purified poloxamine 1107 claim 1 , and purified poloxamine 1307.4. The method of claim 1 , wherein said composition further comprises a therapeutic agent.5. The method of claim 1 , wherein said composition further comprises a therapeutic agent; and the therapeutic agent is selected from the group consisting of antiinflammatories claim 1 , ...

Atraumatic Occlusion Balloons and Skirts, and Methods of Use Thereof

One aspect of the present invention relates to catheters that can be placed in or around bodily conduits to occlude or widen a biological lumen without imparting significant trauma to the lumen. In certain embodiments, the invention particularly relates to the use of a polymer composition which can be made to gel upon insertion into said balloon or skirt. In certain embodiments, the inflating viscous polymer composition is a liquid at room temperature and a gel at mammalian physiological temperature. In certain embodiments, the inflating viscous polymer composition comprises an optionally purified inverse thermosensitive polymer.

Intra-Operative Heart Size Measuring Tool

A heart size measuring tool includes a tubular body, a flexible measuring cord having length indicia, a measuring cord support mechanism movable between retracted and extended states with respect to the body, and an actuating mechanism to move the measuring cord support mechanism. When in the retracted state the measuring cord support mechanism is positioned within the tubular body with the measuring cord in a collapsed position. When the measuring cord support mechanism is in the extended state the measuring cord extends around a portion of a heart to be measured. A scale on the body can be used in connection with the indicia on the measurement cord to provide a reading of the heart size. 1inserting into a patient's body through a minimally invasive access port a heart measurement tool having a measurement device movable between extended and retracted states;positioning a distal end portion of the heart measurement tool adjacent to an apex of the patient's heart while the measurement device is in the retracted state;actuating the measurement tool to move the measurement device to the extended state around at least a portion of the patient's heart;determining the heart size measurement using the measurement device in the extended state; andactuating the measurement tool to move the measurement device to the retracted state; withdrawing the measurement tool from the patient's body.. A method for measuring a size of a patient's heart in connection with the implantation of a therapeutic device surrounding at least a portion of the heart, including: This application is a continuation of U.S. patent application Ser. No. 15/223,973 filed Jul. 29, 2016, which is a continuation of U.S. patent application Ser. No. 14/698,689 filed Apr. 28, 2015 (now U.S. Pat. No. 9,427,318 issued Aug. 30, 2016), which is a continuation of U.S. application Ser. No. 13/261,173, filed on Jun. 29, 2012 (now U.S. Pat. No. 9,044,169 issued Jun. 2, 2015), which is a United States national stage ...

NON-AXISYMMETRIC AORTIC VALVE DEVICES

The present disclosure provides aortic valve prosthetic devices that are constructed in a non-axisymmetric shape, or are expandable to a non-axisymmetric shape for improved results in the repair of defective aortic valves. The devices can be surgically implanted, or they can be implanted percutaneously through an insertion catheter. The expandable devices can be self-expanding or expanded by an inflatable balloon to a non-axisymmetric cross-section geometry. 1. A non-axisymmetric device for implantation into an aortic valve of a mammal.2. The device of claim 1 , wherein the device comprises a non-axisymmetric cross-sectional shape.3. The device of claim 2 , wherein the device comprises an elliptical cross-sectional shape.4. The device of claim 3 , further described as comprising a base and commissure support members attached to the base claim 3 , wherein the members flare outwardly from the base at an angle of from 8°-12° from a line perpendicular to the outer edge of the elliptical cross-section.5. The device of claim 4 , wherein the members extend away from the base at an outward angle of about 10° from a line perpendicular to the outer edge of the elliptical cross-section.6. The device of claim 3 , wherein the ratio of the major axis of the ellipse to the minor axis of the ellipse is between about 1.2 and 1.8.7. The device of claim 6 , wherein the ratio of the major axis of the ellipse to the minor axis of the ellipse is about 1.5.8. The device of claim 3 , wherein the length of the major axis of the elliptical cross-section is between about 10 millimeters and about 35 millimeters.9. The device of claim 3 , wherein the length of the minor axis of the elliptical cross-section is between about 8 millimeters and about 25 millimeters.10. The device of claim 1 , wherein the device is non-axisymmetrically constructed.11. The device of claim 10 , wherein the device comprises at least two different materials.12. The device of claim 10 , wherein the device comprises at ...

TISSUE LIGATION DEVICES AND CONTROLS THEREFOR

Described here are devices for closing one or more tissues, and handles for controlling these devices. Generally, the devices described here comprise a snare loop assembly, wherein the snare loop assembly comprises a snare and a suture loop, and a handle for controlling the snare loop assembly. In some variations the snare loop assembly may comprise a retention member that may releasably connect the suture loop to the snare. In other variations the devices comprise one or more force-reducing suture locks to help prevent the suture loop from inadvertently disengaging from the snare loop assembly. In still other variations, the excess-suture management features. The handles described here may be configured to remove excess suture from a suture loop, and may also be configured to release the suture loop from the snare loop assembly. 1. A tissue closure device comprising:an elongate body; anda snare loop assembly, wherein the snare loop assembly comprises a snare, a suture loop, and a force-reducing suture lock releasably coupling the snare to the suture loop.2. The device of wherein the snare loop assembly further comprises a retention member releasably coupling the snare to the suture loop.3. The device of wherein the elongate body comprises a first lumen and a second lumen.4. The device of wherein the device further comprises separation tubing disposed in the first lumen claim 3 , and wherein the separation tubing comprises a first sub-lumen and a second sub-lumen.5. The device of wherein at least a portion of suture loop is housed within the first and second sub-lumens of the separation tubing.6. The device of further comprising a suture tube claim 5 , wherein a first end of the suture tube is attached to the separation tubing and a second end of the suture tube is attached to the snare loop assembly claim 5 , and wherein the suture tube releasably houses at least a portion of the suture loop.7. The device of wherein the suture tube comprises a plurality of cuts or ...

CARDIAC TREATMENT SYSTEM AND METHOD

Devices and methods for providing localized pressure to a region of a patient's heart to improve heart functioning, including: (a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and (b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart. 1. A cardiac implant for implantation around an exterior of a heart , the implant comprising:an implant body comprising a mesh material that is formed into a generally tubular configuration, the implant body comprising a leading end portion defining an open leading end and a trailing end portion defining an open trailing end of a diameter that is less than a diameter of the open leading end, the trailing end portion having a length configured to extend proximal of the apex of the heart when the leading end portion is positioned in an atrial-ventricular groove of the heart; anda fillable bladder mounted to the implant body and positioned relative to the open leading end such that, when the leading end portion is positioned in the atrial-ventricular groove, the fillable bladder is positionable on an exterior of a heart wall.2. The cardiac implant of claim 1 , wherein the length of the trailing end portion is sized such that portions of the trailing end portion are extendable around the apex of the heart to fully cover the apex of the heart when the leading end portion is positioned in the atrial-ventricular groove of the heart.3. The cardiac implant of claim 2 , wherein the length of the trailing end portion is sized such that at least a proximal-most portion of the trailing end portion is removable while a ...

CARDIAC TREATMENT SYSTEM AND METHOD

Devices and methods for providing localized pressure to a region of a patient's heart to improve heart functioning, including: (a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and (b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart. 1. A delivery system for delivering an implantable cardiac device , the delivery system comprising:an elongate barrel;a plurality of elongate members configured to extend along a length of the elongate barrel and extend distally from the elongate barrel, and being advanceable distally with respect to the elongate barrel, each of the elongate members comprising a distal end for attachment to a cardiac implant configured to be implanted around an exterior of a heart,a control mechanism configured to extend and retract the plurality of elongate members relative to the elongate barrel; anda handle assembly comprising a pistol grip configured to be held by a first hand of an operator while the operator uses a second hand to operate the control mechanism for the extension and retraction of the plurality of elongate members.2. The delivery system of claim 1 , wherein the control mechanism comprises a respective actuator for each of the plurality of elongate members.3. The delivery system of claim 1 , further including a locking mechanism to lock the control mechanism in a position that holds the plurality of elongate members in a retracted position.4. The delivery system of claim 1 , further including a heart stabilizer assembly extending through the elongate barrel and longitudinally slideable within the elongate ...

DEVICES AND METHODS FOR FISTULA FORMATION

Described here are devices and methods for forming a fistula between two vessels. In some instances, the fistula may be formed between a proximal ulnar artery and a deep ulnar vein. The fistula may be formed using an electrode, and may be formed with a first catheter placed in a first blood vessel and a second catheter placed in a second blood vessel. In some instances, access to the proximal ulnar artery may be achieved through a brachial artery, and access to the deep ulnar vein may be achieved through a brachial vein. 1. A method for treating a patient comprising:forming a first fistula between a proximal ulnar artery and a first deep ulnar vein.2. The method of further comprising endovascularly advancing a distal portion of a first catheter into the first deep ulnar vein.3. The method of wherein the first catheter comprises a fistula-forming element claim 2 , and wherein forming the first fistula between the proximal ulnar artery and the first deep ulnar vein comprises forming the first fistula using the fistula-forming element.4. The method of wherein the fistula-forming element comprises an electrode.5. The method of further comprising moving the electrode away from the first catheter against a vessel wall of the deep ulnar vein and wherein forming the first fistula between the proximal ulnar artery and the first deep ulnar vein comprises ablating the vessel wall of the deep ulnar vein and a vessel wall of the ulnar artery.6. The method of further comprising advancing a distal portion of a second catheter into the ulnar artery.7. The method of wherein the first and second catheters each comprise one or more magnets and further comprising aligning the first and second catheters using the one or more magnets of each of the first and second catheters.8. The method of wherein the second catheter comprises a fistula-forming element claim 6 , and wherein forming the first fistula between the proximal ulnar artery and the first deep ulnar vein comprises forming the ...

CARDIAC TREATMENT SYSTEM

An assembly for providing localized pressure to a region of a patient's heart to improve heart functioning, including: (a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and (b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart. 1. An assembly for providing localized pressure to a region of a patient's heart to improve heart functioning , comprising:(a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and(b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface positioned adjacent to the heart such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart.2. The system of claim 1 , wherein the jacket is made of a knit mesh.3. The system of claim 1 , wherein the jacket is made of a polymer.4. The system of claim 3 , wherein the polymer is high-density polyethylene.5. The system of claim 1 , wherein the jacket is made of metal.6. The system of claim 1 , wherein jacket has a bottom end that is cinched closed.7. The system of claim 1 , wherein the inflatable bladder has a supply line connected thereto claim 1 , and wherein the supply line is positioned inside the jacket and extends out of an open bottom end of the jacket adjacent to the apex of the heart.8. The system of claim 1 , ...

Cryolipolysis devices and methods therefor

Described herein are cryolipolysis devices, systems, and methods for facilitating percutaneous access to a target blood vessel by performing cryolipolysis on subcutaneous adipose tissue obscuring the target blood vessel (e.g., a vessel used for hemodialysis treatment). Generally, the devices include a cooling member carrying a coolant that cools a selected portion of adipose tissue overlying the target blood vessel to reduce the selected portion of adipose tissue, thereby forming a depression in the adipose tissue and allowing the target blood vessel closer to the surface of the skin. In some variations, the cooling member is placed subcutaneously to directly cool the selected portion of adipose tissue. In other variations, the cooling member is placed external to the patient to indirectly cool the selected portion of adipose tissue through the skin.

INTRAATRIAL VENTRICULAR ASSIST DEVICE

A medical devices and methods related thereto are disclosed. In an embodiment, the medical device including a pump configured to be inserted within an atrium of a heart, said pump comprising an inlet and an outlet. In addition, the pump includes a flexible outflow conduit coupled to the outlet and configured to carry blood. The outflow conduit includes a radially inner surface defining a throughbore, and a radially outer surface. Further, the pump comprises a driveline configured to conduct control and power signals between the pump and an external device. The driveline extends through the outflow conduit between the radially inner surface and the radially outer surface. 1. A medical device comprising:a pump configured to be inserted within an atrium of a heart, said pump comprising an inlet and an outlet;a flexible outflow conduit coupled to the outlet and configured to carry blood, wherein the outflow conduit includes a radially inner surface defining a throughbore, and a radially outer surface; anda driveline configured to conduct control and power signals between the pump and an external device, wherein the driveline extends through the outflow conduit between the radially inner surface and the radially outer surface.2. The medical device of claim 1 , wherein the outflow conduit comprises:an inner tubular layer, wherein the inner tubular layer includes the radially inner surface; andan outer tubular layer, wherein the outer tubular layer includes the radially outer surface;wherein the driveline is disposed between the inner tubular layer and the outer tubular layer.3. The medical device of claim 2 , wherein the driveline is configured to be peeled away from the inner tubular layer.4. The medical device of claim 2 , wherein each of the inner tubular layer and the outer tubular layer comprise electrically insulating materials.5. The medical device of claim 4 , wherein the outer tubular layer comprises polytetrafluoroethylene (PTFE) claim 4 , and the inner tubular ...

APPARATUS AND METHOD FOR GASTRIC VOLUME REDUCTION UTILIZING AN EXPANDABLE MEMBER

A method is used to reduce a volume of a stomach of a patient. The method includes inverting a portion of a stomach wall to thereby create an inverted portion. An expandable member is positioned adjacent to the outer surface of the inverted portion. The expandable member is expanded to thereby expand the inverted portion. The expanded expandable member has a first outer diameter. A base region of the inverted portion is cinched to thereby capture the expanded expandable member in the expanded inverted portion. The expanded expandable member has a first outer diameter. Expanding and cinching provide a cinch diameter to first outer diameter ratio from approximately 0.5:1 to approximately 0.9:1. 1. A method of reducing a volume of a stomach of a patient , the method comprising:(a) inverting a portion of a stomach wall to thereby create an inverted portion, wherein the stomach wall has an inner surface and an outer surface;(b) positioning an expandable member adjacent to the outer surface of the inverted portion;(c) expanding the expandable member to thereby expand the inverted portion, wherein the expanded expandable member has a first outer diameter; and(d) cinching a base region of the inverted portion to thereby capture the expanded expandable member in the expanded inverted portion, wherein cinching comprises applying a cinch diameter to the base region;wherein expanding and cinching provide a cinch diameter to first outer diameter ratio from approximately 0.5:1 to approximately 0.9:1.2. The method of claim 1 , wherein cinching the base region comprises cinching a cinch assembly around an inner surface of the stomach wall at the base region of the inverted portion.3. The method of claim 2 , wherein the cinch assembly comprises a strap and a head claim 2 , wherein the head comprises a driving element configured to drive the strap through the head claim 2 , wherein cinching the cinch assembly comprises driving the driving element.4. The method of claim 3 , wherein ...

DEVICES AND METHODS FOR FORMING A FISTULA

Described here are devices, systems and methods for forming a fistula between two blood vessels. Generally, the systems may comprise a first catheter which may comprise a fistula-forming element. The fistula-forming element may comprise one or more electrodes, mechanical cutting elements, laser sources, or combinations thereof, and may be used to assist in fistula formation. In some instances, a system may comprise a second catheter, which may comprise a fistula-forming element. One or more of the catheters may comprise one or more markers, magnetic alignment elements, and/or one shape-changing elements. 124-. (canceled)25. A method for forming a fistula using a first catheter and a second catheter , wherein the first catheter comprises a catheter body and a shaped lead wire , wherein the lead wire is spring biased toward an extended position in which a distal portion of the lead wire is spaced apart from the catheter body , and the first catheter is configured to hold the lead wire in a compressed configuration within the catheter body and is sized for advancement within a first vessel , and wherein the second catheter comprises a pocket comprising an insulating material for receiving the distal portion of the lead wire and is sized for advancement within a second vessel , comprising:forming a fistula using the first and second catheters.26. The method of claim 25 , wherein forming a fistula comprises advancing the first catheter to a target location within the first vessel and advancing the second catheter to a target location within the second vessel.27. The method of claim 26 , wherein the first catheter is advanced with the lead wire in the compressed configuration claim 26 , and wherein forming a fistula further comprises moving the lead wire proximally relative to the catheter body to release the distal portion of the lead wire from the compressed configuration.28. The method of claim 27 , further comprising moving the lead wire proximally relative to the ...

METHODS AND DEVICES TO CLEAR OBSTRUCTIONS FROM MEDICAL TUBES

A device for clearing obstructions from a medical tube, such as a chest tube, is disclosed in various embodiments. The device features a clearance member in the form of a loop. The loop desirably has a diameter that substantially corresponds to the inner diameter of the medical tube. Also desirably, the loop presents a substantially unobstructed pathway therethrough for the flow of material from a location in the medical tube distal to the loop to a location in the medical tube proximal to the loop regardless whether the clearance member is being translated or is at rest in the medical tube. Methods of utilizing such a device are also disclosed. 1. A method of clearing obstructions from a medical tube , comprising: actuating a clearance member disposed within said medical tube , said clearance member being normally disposed at a resting position adjacent a distal end of said medical tube , wherein said actuating step comprises initially withdrawing said clearance member in a proximal direction from said resting position to engage and draw debris proximally , away from said medical tube distal end , and thereafter returning said clearance member to said resting position.2. The method of claim 1 , further comprising repeating said actuating and returning steps.3. The method of claim 1 , further comprising actuating a guide member formed with or attached to said clearance member to thereby actuate said clearance member claim 1 , said guide member being actuated from outside said medical tube.4. The method of claim 3 , said guide member comprising a guide wire claim 3 , said clearance member comprising a wire loop formed from or attached to a terminal portion of said guide wire.5. The method of claim 3 , said guide member and clearance member being configured so that said clearance member does not emerge from said distal end of said medical tube either in said resting position or during said actuating or returning steps.6. The method of claim 3 , wherein a shuttle is ...

VASCULAR STENT DEVICES AND METHODS

Described here are devices, systems, and methods for cannulating a vessel. Generally, the method may comprise advancing a stent into a first vessel and deploying the stent in the first vessel to hold open one or more valves. This may permit retrograde blood flow through the blood vessel in peripheral vasculature and aid in cannulation of the blood vessel. 1. A catheter system comprising:a stent comprising one or more apertures, the stent configured to hold open one or more venous valves and receive a needle through the one or more apertures;a first catheter comprising a fistula-forming element; anda stent detector comprising a sensor configured to noninvasively detect a location of the stent.2. The system of claim 1 , wherein the stent comprises first struts and second struts having different thicknesses.3. The system of claim 1 , further comprising a second catheter comprising a push wire configured to deploy one or more stents sequentially from a distal end of the second catheter.4. The system of claim 3 , wherein a distal end of the push wire pushes the one or more stents out of the second catheter.5. The system of claim 1 , wherein the fistula-forming element is an electrode.6. The system of claim 2 , wherein the first struts form a first set of diamonds claim 2 , and the second struts form a second set of diamonds within the first set of diamonds.7. The system of claim 1 , further comprising an output device communicatively coupled to the stent detector and configured to output a warning when the stent is not detected within a predetermined range.8. The system of claim 1 , further comprising an output device communicatively coupled to the stent detector and configured to output a signal when the stent detector is above the stent.9. The system of claim 8 , wherein the signal is a visual signal.10. The system of claim 1 , wherein the sensor of the stent detector is a metal detector.11. The system of claim 1 , wherein the stent detector emits a magnetic field.12. ...

TISSUE LIGATION DEVICES AND CONTROLS THEREFOR

Described here are devices for closing one or more tissues, and handles for controlling these devices. Generally, the devices described here comprise a snare loop assembly, wherein the snare loop assembly comprises a snare and a suture loop, and a handle for controlling the snare loop assembly. In some variations the snare loop assembly may comprise a retention member that may releasably connect the suture loop to the snare. In other variations the devices comprise one or more force-reducing suture locks to help prevent the suture loop from inadvertently disengaging from the snare loop assembly. In still other variations, the excess-suture management features. The handles described here may be configured to remove excess suture from a suture loop, and may also be configured to release the suture loop from the snare loop assembly. 138-. (canceled)39: A tissue closure device comprising:an elongate body; anda snare loop assembly, wherein the snare loop assembly comprises a snare, a suture loop, a retention member releasably coupling the snare to the suture loop, and a force-reducing suture lock releasably coupling the snare to the suture loop.40: The device of claim 39 , wherein the force-reducing suture lock is configured to prevent the suture loop from releasing from the retention member prematurely.41: The device of wherein the force-reducing suture lock comprises shrink tubing.42: The device of wherein the force-reducing suture lock comprises a first lumen and a second lumen.43: The device of wherein a first portion of the snare is housed within the first lumen and a first portion of the suture loop is housed within the second lumen.44: The device of wherein the force-reducing suture lock further comprises a slit and is configured to release the first portion of the suture loop via the slit.45: The device of wherein the first portion of the suture loop is released from the force-reducing suture lock by application of a force to the suture.46: The device of wherein ...

DEVICES AND METHODS FOR FISTULA FORMATION

Described here are devices and methods for forming a fistula between two vessels. In some instances, the fistula may be formed between a proximal ulnar artery and a deep ulnar vein. The fistula may be formed using an electrode, and may be formed with a first catheter placed in a first blood vessel and a second catheter placed in a second blood vessel. In some instances, access to the proximal ulnar artery may be achieved through a brachial artery, and access to the deep ulnar vein may be achieved through a brachial vein. 129-. (canceled)30: A method for treating a patient comprising:forming an access site in an arm location; andforming a first fistula between a proximal ulnar artery and a first deep ulnar vein, the first deep ulnar vein being substantially parallel to the proximal ulnar artery between a brachial artery and an interosseous artery.31: The method of wherein the arm location is a wrist claim 30 , forearm claim 30 , or upper arm.32: The method of wherein the access site is formed in an ulnar artery at the wrist.33: The method of further comprising endovascularly advancing a distal portion of a first catheter through the access site and into an ulnar artery.34: The method of further comprising endovascularly advancing a distal portion of a first catheter into the first deep ulnar vein.35: The method of wherein the first catheter comprises a fistula-forming element claim 34 , and wherein forming the first fistula between the proximal ulnar artery and the first deep ulnar vein comprises forming the first fistula using the fistula-forming element.36: The method of wherein the fistula-forming element comprises an electrode.37: The method of further comprising moving the electrode away from the first catheter against a vessel wall of the first deep ulnar vein and wherein forming the first fistula between the proximal ulnar artery and the first deep ulnar vein comprises ablating the vessel wall of the first deep ulnar vein and a vessel wall of the proximal ...

PERICARDIAL SPACE IMAGING FOR CARDIAC SUPPORT DEVICE IMPLANTATION

A method for implanting a cardiac support device (CSD) on a patient's heart. An amount of contrast agent sufficient to cause structures on the heart to be visible upon fluoroscopic or other imaging is introduced into the pericardial space surrounding the heart. The heart and contrast agent are imaged to provide a visual indication of the location of the structures of the heart. The CSD is placed on the heart using the visual indications provided by the imaging. 1. A method for implanting a CSD on a patient's heart , including:introducing contrast agent into a pericardial space surrounding the heart;imaging the heart and contrast agent to provide a visual indication of the location of structures of the heart; andplacing the CSD on the heart, including using the visual indications to position the CSD.2. The method of wherein:imaging the heart includes providing visual indications of the location of the A-V groove; andplacing the CSD on the heart includes using the visual indication of the A-V groove.3. The method of any of for implanting a CSD having radioopaque markers claim 1 , wherein:imaging the heart further includes imaging the CSD markers to provide a visual indication of the markers; andplacing the CSD on the heart includes using the visual indication of the location of the structures on the heart and the visual indication of the markers to position the CSD.4. The method of and further include flushing the contrast agent from the pericardial space after placing the CSD on the heart.5. The method of wherein introducing contrast agent includes:inserting a tubular structure through the pericardium into the pericardial space; anddelivering contrast agent into the pericardial space through the tubular structure.6. The method of wherein:introducing contrast agent includes introducing a fluoroscopic contrast agent; andimaging the heart and contrast agent includes fluoroscopically imaging the heart and contrast agent.7. The method of wherein:introducing contrast agent ...

ISOLATION BOX FOR PROTECTING READING MATERIAL

A portable reverse isolation box (PRIB) for protecting an object from the environment and/or protecting a user from the object, the PRIB comprising: 1. A portable reverse isolation box (PRIB) for protecting an object from the environment and/or protecting a user from the object , the PRIB comprising:a housing comprising a container and a lid, wherein the container has structural integrity and at least a portion of the lid is transparent, and further wherein the housing forms an airtight and watertight isolation bay when the lid is mounted on the container;a port formed in the container; anda disposable flexible element mounted in the port in an airtight and watertight relationship, the flexible element being capable of assuming a concave configuration so as to permit a user to manipulate the object within the isolation bay without opening the lid.2. A portable reverse isolation box (PRIB) according to further comprising a book disposed in the isolation bay.3. A portable reverse isolation box (PRIB) according to wherein the container is sized so that the book is retained at a specific open page when the lid is mounted on the container.4. A portable reverse isolation box (PRIB) according to further comprising a writing instrument and a writing medium disposed in the isolation bay.5. A portable reverse isolation box (PRIB) according to further comprising food and a food implement disposed in the isolation bay.6. A portable reverse isolation box (PRIB) according to wherein the food implement comprises a knife.7. A portable reverse isolation box (PRIB) according to further comprising a playing implement disposed in the isolation bay.8. A portable reverse isolation box (PRIB) according to wherein the playing implement comprises a game board.9. A portable reverse isolation box (PRIB) according to wherein the playing implement comprises a deck of playing cards.10. A portable reverse isolation box (PRIB) according to further comprising at least four ports formed in the ...

SYSTEMS AND METHODS FOR ADHERING VESSELS

Described here are devices, systems, and methods for adhering tubular structures, such as blood vessels. Generally, the methods may comprise advancing a first catheter comprising a first adhesion element into a first blood vessel and a second catheter comprising a second adhesion element into a second blood vessel. The vessels may be adhered together by heating tissue using the first and second adhesion elements. 1. A system for adhering two tubular structures together , comprising:a first catheter comprising a first adhesion element, wherein the first adhesion element is magnetic and comprises a flat contact surface;a second catheter comprising a second adhesion element, wherein the second adhesion element is magnetic and comprises a flat contact surface; anda power source connected to the first and second adhesion elements.2. The system of claim 1 , wherein the first adhesion element is located at a distal end of the first catheter claim 1 , and the second adhesion element is located at a distal end of the second catheter.3. The system of claim 1 , wherein the first adhesion element is coated with one or more layers of a fluoropolymer.4. The system of claim 1 , wherein the first catheter comprises a proximal portion and a distal portion claim 1 , wherein the largest cross-sectional dimension of the distal portion is larger than the largest cross-sectional dimension of the proximal portion claim 1 , and wherein the first adhesion element is located on the distal portion.5. The system of claim 4 , wherein at least one of the pushability claim 4 , flexibility claim 4 , or torquability of the first catheter is adjustable.6. The system of claim 1 , wherein the first catheter comprises a distal portion claim 1 , an inner proximal portion claim 1 , and an outer proximal portion.7. The system of claim 6 , wherein the outer proximal portion is slidable relative to the distal portion.8. The system of claim 7 , wherein the distal portion is configured to extend away from the ...

DEVICES AND METHODS FOR ADVANCING A WIRE

Systems and methods for positioning a wire for advancement through a vessel wall, and advancing it through one or more vessel walls, generally include a delivery catheter and an alignment catheter or a receiving catheter, and a guidewire. In some variations, the systems and methods may be used to bypass an occlusion or other barrier that may prevent advancement of a wire or tools through an endoluminal space. In these variations, the systems and methods include a delivery catheter, a bypass catheter, a receiving catheter, and a guidewire. The delivery and receiving catheters each generally include a side aperture, a deflection surface, and an alignment element, and the bypass catheter generally includes two side apertures, two deflectors, and two alignment elements. In some variations, the systems and methods may assist in treatment of a patient suffering from critical limb ischemia. 1. A system for advancing a guidewire through a vessel wall comprising:a first catheter comprising a catheter body having a first lumen therethrough and a first side aperture, a first deflection surface, and a first alignment element;a second catheter comprising a catheter body having a second lumen therethrough and a second side aperture, a second deflection surface, and a second alignment element; anda guidewire,wherein the first and second alignment elements are configured to align the first and second side apertures to create a guidewire pathway through the first and second catheters.2. The system of claim 1 , wherein the first catheter is a delivery catheter and the second catheter is a receiving catheter.3. The system of claim 1 , wherein the first and second alignment elements each comprise a magnet or a magnetic array.4. The system of claim 1 , wherein the first catheter further comprises a third alignment element and the second catheter further comprises a fourth alignment element.5. The system of claim 4 , wherein the third and fourth alignment elements each comprise a magnet ...

METHODS AND DEVICES TO CLEAR OBSTRUCTIONS FROM MEDICAL TUBES

A device for clearing obstructions from a medical tube, such as a chest tube, is disclosed in various embodiments. The device features a clearance member in the form of a loop. The loop desirably has a diameter that substantially corresponds to the inner diameter of the medical tube. Also desirably, the loop presents a substantially unobstructed pathway therethrough for the flow of material from a location in the medical tube distal to the loop to a location in the medical tube proximal to the loop regardless whether the clearance member is being translated or is at rest in the medical tube. Methods of utilizing such a device are also disclosed. 1. A medical-tube assembly comprising a medical tube , a clearance device adapted to couple with and dislodge debris accumulated within said medical tube , and a COsensor provided in fluid communication with said medical tube to sense the presence of COlevels in said medical tube.2. The medical-tube assembly of claim 1 , wherein the COsensor is placed between the medical tube and a suction source.3. The medical-tube assembly of claim 1 , wherein the COsensor is coupled to the medical tube via a lateral channel in fluid communication with and extending from the medical tube.4. The medical-tube assembly of claim 1 , wherein the clearance device comprises an elongate guide member at least partially disposed in said medical tube claim 1 , and a clearance member attached to or formed integrally with said guide member.5. The medical-tube assembly of claim 1 , wherein the clearance device comprises a clearance member adapted to be translated through said medical tube via a guide wire to dislodge debris accumulated therein.6. A method of treating a patient claim 1 , comprising:implanting a medical tube in a patient's body cavity;draining fluid from the patient's body cavity;actuating a clearance device within the medical tube to dislodge debris accumulated within the medical tube; and{'sub': '2', 'detecting COwithin the medical tube ...

BABY NIPPLE ASSEMBLY FOR USE WITH FLEXIBLE DRINK POUCHES

A novel baby nipple assembly for use with a flexible drink pouch, wherein the baby nipple assembly generally comprises a mount subassembly (sometimes hereinafter referred to as simply “the mount” or “the disk”) for attachment to the flexible drink, pouch, and a nipple subassembly (sometimes hereinafter referred to as simply “the nipple”) for connection to the mount subassembly, wherein the mount subassembly comprises a relatively large fiat element for adhesion to an outside surface of the flexible drink pouch, and the nipple subassembly comprises (1) means for connection to the mount subassembly, (ii) a sharp tube for extending through the mount subassembly and puncturing the side all of the flexible drink pouch, and (iii) a soft nipple in fluid communication with the sharp tube, whereby a baby or young child can suckle on the nipple and receive the beverage from the flexible drink pouch. 1. A drink assembly comprising:a mount subassembly for attachment to a pre-existing flexible drink pouch, the mount subassembly comprising a body having a proximal side and a distal side and an opening extending from the proximal side to the distal side, and an adhesive mounted on the distal side for affixing the mount subassembly to the flexible drink pouch; anda mouthpiece subassembly for releasable attachment to the mount subassembly, the mouthpiece subassembly comprising a mouthpiece having an opening therein, and a tube extending distally from the mouthpiece, with the interior of the tube communicating with the opening in the mouthpiece.2. A drink assembly according to wherein the mouthpiece subassembly comprises a mouthpiece lock mechanism for releasably locking to a mount lock mechanism connected to the mount subassembly.3. A drink assembly according to wherein mouthpiece lock mechanism comprises at least one flange claim 2 , and further wherein the mount lock mechanism comprises at least one flange mounted on a post.4. A drink assembly according to wherein the mouthpiece ...

Method and apparatus for treating a patient by intentionally occluding a blood vessel, including method and apparatus for inducing weight loss in a patient by intentionally occluding the celiac artery

A method for inducing weight loss in a patient, the method comprising: intentionally occluding a blood vessel so as to create hypoperfusion in a gastrointestinal organ serviced by the blood vessel, whereby to interfere with normal gastrointestinal function and thereby induce weight loss in a patient.

INTRAATRIAL VENTRICULAR ASSIST DEVICE

A medical devices and methods related thereto are disclosed. In an embodiment, the medical device including a pump configured to be inserted within an atrium of a heart, said pump comprising an inlet and an outlet. In addition, the pump includes a flexible outflow conduit coupled to the outlet. The outflow conduit includes a radially inner surface defining a throughbore, and a radially outer surface. Further, the pump comprises a driveline configured to conduct control and power signals between the pump and an external device. The driveline extends through the outflow conduit between the radially inner surface and the radially outer surface. 1. A medical device comprising:a pump configured to be inserted within an atrium of a heart, said pump comprising an inlet and an outlet;a flexible outflow conduit coupled to the outlet, wherein the outflow conduit includes a radially inner surface defining a throughbore, and a radially outer surface; anda driveline configured to conduct control and power signals between the pump and an external device, wherein the driveline extends through the outflow conduit between the radially inner surface and the radially outer surface.2. The medical device of claim 1 , wherein the outflow conduit comprises:an inner tubular layer, wherein the inner tubular layer includes the radially inner surface; andan outer tubular layer, wherein the outer tubular layer includes the radially outer surface;wherein the driveline is disposed between the inner tubular layer and the outer tubular layer.3. The medical device of claim 2 , wherein the driveline is configured to be peeled away from the inner tubular layer.4. The medical device of claim 2 , wherein each of the inner tubular layer and the outer tubular layer comprise electrically insulating materials.5. The medical device of claim 4 , wherein the outer tubular layer comprises polytetrafluoroethylene (PTFE) claim 4 , and the inner tubular layer comprises expanded PTFE (ePTFE).6. The medical device ...

METHOD AND APPARATUS FOR RESECTING AND REPLACING AN AORTIC VALVE

Apparatus for resecting a diseased heart valve, the apparatus comprising: a body portion; a first handle and a second handle; a cutting blade; a set of retaining arms; a pass-off tool having a first attachment device configured to selectively engage the first handle attached to the body portion so as to allow placement of the second handle of the body portion adjacent to the diseased heart valve, and a controller tool having a second attachment device at the distal end thereof, the second attachment device configured to selectively engage the second handle attached to the body portion so as to allow positioning of the body portion adjacent to the diseased heart valve, a cutting blade actuator configured to cause the cutting blade to selectively rotate, and a retaining arm actuator configured to selectively position the set of retaining arms from the contracted state to the expanded state.

METHODS FOR TREATING HYPERTENSION AND REDUCING BLOOD PRESSURE WITH FORMATION OF FISTULA

Described here are devices and methods for treating hypertension by forming a fistula between two blood vessels to reduce blood pressure of a patient. The fistula may be formed using a catheter having an electrode that is placed in a first blood vessel. In some instances, a desired amount of blood pressure is determined. In other instances, the hypertension is drug resistant hypertension. 1. A method of treating a patient having hypertension comprising:determining a desired amount of blood pressure reduction;generating a lumped parameter model of a fistula network;selecting a fistula characteristic based on the lumped parameter model of the fistula network and the desired amount of blood pressure reduction;advancing a first catheter into a first blood vessel of the patient, wherein the first catheter comprises an electrode; andforming the fistula between the first blood vessel and a second blood vessel to reduce a blood pressure of the patient.2. The method of claim 1 , wherein the fistula is configured to reduce the blood pressure by about at least 15%.3. The method of claim 1 , wherein the patient has a systolic blood pressure of more than about 150 mmHg.4. The method of claim 1 , wherein the hypertension is drug resistant hypertension.5. The method of claim 1 , further comprising selecting the first blood vessel and the second blood vessel based on the desired amount of blood pressure reduction.6. The method of claim 1 , wherein the fistula characteristic comprises one or more of fistula size claim 1 , number of fistulas claim 1 , spacing between the fistulas claim 1 , and fistula arrangement.7. The method of claim 6 , wherein the fistula characteristic comprises the fistula arrangement claim 6 , the fistula arrangement comprising a series of fistulas located axially along the blood vessels.8. The method of claim 1 , further comprising modifying one or more of the first blood vessel and the second blood vessel.9. The method of claim 8 , wherein modifying one or ...

SYSTEMS AND METHODS FOR INCREASING BLOOD FLOW

Described here are devices, systems, and methods for improving blood flow in a vessel. Generally, the method may comprise advancing a catheter into a first vessel proximal to an occlusion in the first vessel and forming a fistula between the first vessel and a second vessel. This may deliver blood flow around an occlusion to ischemic tissues located in the peripheral vasculature. 1. A method for improving blood flow in a vessel comprising:advancing a first catheter into a first vessel proximal to an occlusion in the first vessel, wherein the first catheter comprises a fistula-forming element;advancing a second catheter into a second vessel, wherein the second vessel is adjacent to the first vessel; andforming a fistula between the first vessel and a second vessel using the fistula-forming element, wherein the fistula allows blood to flow past the occlusion through the second vessel.2. The method of claim 1 , wherein the fistula-forming element comprises an electrode.3. The method of claim 1 , wherein each of the first and second catheters comprises a magnet.4. The method of claim 1 , further comprising providing an embolization coil in the second vessel.5. The method of claim 4 , wherein the embolization coil is located proximal to the occlusion.6. The method of claim 1 , further comprising performing a valvulotomy in the second vessel.7. The method of claim 6 , wherein the valvulotomy is performed distal to the fistula.8. The method of claim 1 , wherein the first vessel is an artery and the second vessel is a vein.9. The method of claim 1 , further comprising advancing a third catheter comprising a second fistula-forming element into the first vessel distal to the occlusion in the first vessel claim 1 , advancing a fourth catheter into the second vessel claim 1 , and forming a second fistula between the first vessel and the second vessel using the second fistula-forming element.10. The method of claim 1 , wherein the second fistula-forming element comprises an ...

DEVICES AND METHODS FOR FORMING A FISTULA

Described here are devices, systems, and methods for forming a fistula between two blood vessels. The systems may comprise a first catheter including a housing and an electrode having a proximal end and a distal end. The proximal end is fixed relative to the housing and the distal end is longitudinally slidable within the housing. 1. A system for forming a fistula between two vessels comprising:a first catheter comprising a housing and an electrode comprising a proximal end and a distal end, wherein the proximal end is fixed relative to the housing and the distal end is longitudinally slidable within the housing.2. The system of claim 1 , wherein the housing comprises an opening and the electrode comprises an intermediate portion between the proximal end and the distal end claim 1 , and wherein the intermediate portion extends into and out of the opening.3. The system of claim 1 , wherein the electrode comprises a leaf spring.4. The system of claim 1 , wherein the first catheter comprises a fluid seal to prevent fluid ingress into the first catheter at the proximal end of the electrode.5. (canceled)6. The system of claim 1 , wherein the electrode varies in width and/or height along its length.7. The system of claim 2 , wherein the intermediate portion of the electrode comprises a plurality of bends.8. The system of claim 2 , wherein the intermediate portion comprises a bend of less than about 40 degrees.9. The system of claim 1 , wherein the electrode comprises a low-profile configuration in which the electrode is recessed into the housing.10. The system of claim 1 , wherein the housing comprises a reservoir between the proximal end of the electrode and a distal end of the first catheter claim 1 , the reservoir configured to hold fluid claim 1 , and wherein the electrode is configured to generate plasma from the fluid in the reservoir.11. (canceled)12. The system of claim 1 , further comprising a second catheter comprising a second housing and a protruding backstop. ...

Pericardial Space Imaging for Cardiac Support Device Implantation

A method for implanting a cardiac support device (CSD) on a patient's heart. An amount of contrast agent sufficient to cause structures on the heart to be visible upon fluoroscopic or other imaging is introduced into the pericardial space surrounding the heart. The heart and contrast agent are imaged to provide a visual indication of the location of the structures of the heart. The CSD is placed on the heart using the visual indications provided by the imaging.

APPARATUS AND METHOD FOR THE LIGATION OF TISSUE

A novel catheter-based system which ligates the left atrial appendage (LAA) on the outside of the heart, preferably using a combination of catheters and/or instruments, e.g., a guide catheter positioned inside the left atrial appendage which may assist in locating the left atrial appendage and/or assist in the optimal placement of a ligature on the outside of the appendage, and a ligating catheter and/or instrument outside the heart in the pericardial space to set a ligating element at the neck of the left atrial appendage. 162-. (canceled)63: A method for positioning a device near a patient's heart comprising:advancing a first alignment element transeptally into a left atrial appendage;advancing a second alignment element into a pericardial space from outside a patient's heart; andaligning the first and second alignment elements to assist in positioning the device.64: The method of claim 63 , wherein aligning the first and second alignment elements assists in positioning the device in the pericardial space.65: The method of claim 64 , wherein aligning the first and second alignment elements assists in positioning the device at a neck of the left atrial appendage.66: The method of claim 63 , wherein the device comprises a ligating element and the method further comprises advancing the ligating element to the left atrial appendage.67: The method of further comprising ligating the left atrial appendage with the ligating element.68: The method of claim 66 , wherein advancing the ligating element to the left atrial appendage comprises advancing the ligating element relative to the second alignment element.69: The method of claim 66 , wherein the ligating element is reversibly secured to a nitinol structure.70: The method of claim 63 , wherein the alignment elements are aligned end-to-end.71: The method of claim 63 , wherein each of the first and second alignment elements comprise magnets.72: The method of claim 63 , wherein the first alignment element is part of a guide ...

CRYOLIPOLYSIS DEVICES AND METHODS THEREFOR

Described herein are cryolipolysis devices, systems, and methods for facilitating percutaneous access to a target blood vessel by performing cryolipolysis on subcutaneous adipose tissue obscuring the target blood vessel (e.g., a vessel used for hemodialysis treatment). Generally, the devices include a cooling member carrying a coolant that cools a selected portion of adipose tissue overlying the target blood vessel to reduce the selected portion of adipose tissue, thereby forming a depression in the adipose tissue and allowing the target blood vessel closer to the surface of the skin. In some variations, the cooling member is placed subcutaneously to directly cool the selected portion of adipose tissue. In other variations, the cooling member is placed external to the patient to indirectly cool the selected portion of adipose tissue through the skin. 1. A device for facilitating percutaneous access to a target blood vessel in a patient , comprising:a subcutaneous probe to carry a coolant, the probe comprising an adipose tissue interface surface and a treatment segment, wherein the treatment segment defines a delivery lumen extending at least the length of the treatment segment to carry the coolant toward a distal end of the treatment segment and a return lumen to carry the coolant away from the distal end of the treatment segment.2. The device of claim 1 , wherein the treatment segment overlies and is substantially aligned with a treatment portion of the target blood vessel.3. The device of claim 1 , wherein the delivery lumen and the return lumen are in fluid communication with one another at the distal end of the treatment segment.4. The device of claim 3 , wherein at least a portion of the delivery lumen and at least a portion of the return lumen are separated by a porous wall.5. The device of claim 4 , wherein the probe further comprises a valve coupled to the return lumen to control a rate of a phase transformation of the coolant across the porous wall.6. The ...

Device and Method for Automated Insertion of Penetrating Member

An automatic insertion device and method of using the same is provided. A vibrator and an extender are connected to a penetrating member and are both in electrical communication with a controller. A detector identifies a subcutaneous target for insertion and the insertion angle, distance and trajectory for the penetrating member are calculated. The vibrator provides vibrations to the penetrating member and the extender advances the penetrating member for insertion. The vibrator and extender are in electrical communication with one another during the insertion process and adjustments to the insertion speed are made based on feedback of vibrational load encountered by the vibrator during insertion, and adjustments to the vibrations are made based on feedback of insertion load encountered by the extender during insertion. Iterative samples are taken to constantly adjust the operation of one motor based on the operations and feedback from the other motor. 1. A device for inserting a penetrating member into tissue along an insertion axis said comprising:a detector;a controller having a processor and a memory;a vibration assembly connected to the penetrating member, said vibration assembly having a vibrational actuator in electrical communication with at least one of said controller and an extension assembly, said vibrational actuator configured to generate axial vibrations along the insertion axis according to operative vibrational instructions defined at least in part in response to an insertion load, to transmit said axial vibrations to the penetrating member, to detect a vibrational load on said vibrational actuator and to transmit signals indicative of said vibrational load to one of said controller and said extension assembly; andsaid extension assembly connected to the penetrating member and in electrical communication with at least one of said controller and said vibrational assembly, said extension assembly having an extension actuator configured to axially move ...

VASCULAR STENT DEVICES AND METHODS

Described here are devices, systems, and methods for cannulating a vessel. Generally, the method may comprise advancing a stent into a first vessel and deploying the stent in the first vessel to hold open one or more valves. This may permit retrograde blood flow through the blood vessel in peripheral vasculature and aid in cannulation of the blood vessel. 1. A method for cannulating a first vessel comprising:advancing a stent into the first vessel comprising one or more valves;deploying the stent over the one or more valves to hold open the one or more valves; andadvancing a needle through a wall of the first vessel.2. The method of claim 1 , wherein the needle is advanced through an aperture defined in a wall of the stent.3. The method of claim 1 , wherein the needle is advanced through the wall of the first vessel distal to the stent.4. The method of claim 1 , further comprising non-invasively detecting the stent location.5. The method of claim 4 , further comprising positioning the needle over the first vessel using the detected stent location.6. The method of claim 1 , wherein the stent comprises first struts and second struts having different thicknesses.7. The method of claim 1 , wherein the first vessel is a cephalic vein.8. The method of claim 1 , wherein the first vessel is a basilic vein.9. The method of claim 1 , further comprising advancing a first catheter into an artery adjacent to a vein claim 1 , wherein the first catheter comprises a fistula-forming element claim 1 , and forming a fistula between the artery and the vein using the fistula-forming element.10. The method of claim 9 , wherein the stent is deployed distal to the fistula.11. The method of claim 9 , wherein the artery is an ulnar artery and the vein is an ulnar vein.12. The method of claim 9 , further comprising advancing a second catheter into the vein.13. The method of claim 12 , further comprising aligning the first catheter and the second catheter.14. The method of claim 1 , further ...

Apparatus and method for the ligation of tissue

A novel catheter-based system which ligates the left atrial appendage (LAA) on the outside of the heart, preferably using a combination of catheters and/or instruments, e.g., a guide catheter positioned inside the left atrial appendage which may assist in locating the left atrial appendage and/or assist in the optimal placement of a ligature on the outside of the appendage, and a ligating catheter and/or instrument outside the heart in the pericardial space to set a ligating element at the neck of the left atrial appendage.

INTRA-OPERATIVE HEART SIZE MEASURING TOOL

A heart size measuring tool includes a tubular body, a flexible measuring cord having length indicia, a measuring cord support mechanism movable between retracted and extended states with respect to the body, and an actuating mechanism to move the measuring cord support mechanism. When in the retracted state the measuring cord support mechanism is positioned within the tubular body with the measuring cord in a collapsed position. When the measuring cord support mechanism is in the extended state the measuring cord extends around a portion of a heart to be measured. A scale on the body can be used in connection with the indicia on the measurement cord to provide a reading of the heart size. 1. A method for measuring a size of a patient's heart in connection with the implantation of a therapeutic device surrounding at least a portion of the heart , including:inserting into a patient's body through a minimally invasive access port a heart measurement tool having a measurement device movable between extended and retracted states;positioning a distal end portion of the heart measurement tool adjacent to an apex of the patient's heart while the measurement device is in the retracted state;actuating the measurement tool to move the measurement device to the extended state around at least a portion of the patient's heart;determining the heart size measurement using the measurement device in the extended state;actuating the measurement tool to move the measurement device to the retracted state; andwithdrawing the measurement tool from the patient's body.2. The method of wherein determining the heart size measurement includes determining the heart size as a function of a length of measuring cord extending around the heart.3. The method of wherein: the method further includes imaging the measurement tool when the measurement device is in the extended state; and determining the heart size measurement includes determining the measurement as a function of the imaging.4. The ...

Apparatus and method for the ligation of tissue

A novel catheter-based system which ligates the left atrial appendage (LAA) on the outside of the heart, preferably using a combination of catheters and/or instruments, e.g., a guide catheter positioned inside the left atrial appendage which may assist in locating the left atrial appendage and/or assist in the optimal placement of a ligature on the outside of the appendage, and a ligating catheter and/or instrument outside the heart in the pericardial space to set a ligating element at the neck of the left atrial appendage.

DEVICES AND METHODS FOR FORMING A FISTULA

Described here are devices, systems and methods for forming a fistula between two blood vessels. Generally, the systems may comprise a first catheter which may comprise a fistula-forming element. The fistula-forming element may comprise one or more electrodes, mechanical cutting elements, laser sources, or combinations thereof, and may be used to assist in fistula formation. In some instances, a system may comprise a second catheter, which may comprise a fistula-forming element. One or more of the catheters may comprise one or more markers, magnetic alignment elements, and/or one shape-changing elements. 120-. (canceled)21. A catheter system , comprising:a first catheter comprising a first catheter body, a first alignment element, and an electrode; anda second catheter comprising a second catheter body, a second alignment element, and a pocket configured to receive at least a portion of the electrode,wherein the first and second alignment elements are configured to align the first and second catheters relative to each other.22. The system of claim 21 , wherein the pocket comprises an insulating material.23. The system of claim 21 , wherein the first alignment element comprises a first magnetic component claim 21 , and wherein the second alignment element comprises a second magnetic component configured to interact with the first magnetic component.24. The system of claim 23 , wherein the first magnetic component comprises a first mating surface claim 23 , and wherein the second magnetic component comprises a second mating surface claim 23 , and wherein the first mating surface is configured to be attracted to the second mating surface.25. The system of claim 24 , wherein the first and second mating surfaces each comprise a flat surface.26. The system of claim 23 , wherein the first and second magnetic components each comprise at least one box-shaped magnet.27. The system of claim 26 , wherein the first and second magnetic components each comprise a plurality of ...

SYSTEMS AND METHODS FOR INCREASING BLOOD FLOW

Described here are devices, systems, and methods for improving blood flow in a vessel. Generally, the method may comprise advancing a catheter into a first vessel proximal to an occlusion in the first vessel and forming a fistula between the first vessel and a second vessel. This may deliver blood flow around an occlusion to ischemic tissues located in the peripheral vasculature.

METHODS AND APPARATUS FOR INTRODUCING A MEDICAL DEVICE INTO THE BODY OF A PATIENT

An image guided robotic device is provided to perform a diagnostic or therapeutic medical procedure. In one embodiment, the robotic device includes an imaging machine, an actuator, and a controller for controlling the actuator. The robotic device may be configured to introduce a needle, a catheter, or a cannula into an anatomical structure. The device and its components may be sized for use as a portable device and/or operable using one hand of the operator. 1. An image guided device for introducing a medical device into a body structure , comprising:an imaging device for acquiring information of a location of the body structure;an actuator for deploying the medical device, wherein the actuator is pivotally connected to a console by a support arm, and wherein the actuator comprises:a first injector motor; anda second injector motor;a catheter cartridge releasably attached to the actuator, the catheter cartridge containing the medical device, which includes a guide wire, wherein the guide wire is partially disposed in a needle, wherein a catheter is coaxially disposed around a shaft of the needle, and wherein the guide wire is wound around a spool and adapted to be spooled out along with an insertion of the needle;and a controller for receiving and processing information of the location of the body structure and in response controlling the first injector motor to advance or retract the needle and the second injector motor to advance or retract the catheter relative to the needle to place the medical device into the body structure.2. The apparatus of claim 1 , wherein the apparatus is portable.3. The apparatus of claim 1 , wherein the first injector motor is a linear motor.4. The apparatus of claim 2 , wherein the second injector motor is a linear motor.5. The apparatus of claim 3 , further comprising a rotary motor adapted to advance or retract the guide wire through the needle.6. The apparatus of claim 1 , wherein the catheter is configured for simultaneous ...

MAGNETIC ASSISTED IN-SITU TUBULAR STENTGRAFT FENESTRATION

A magnet assisted surgical device, system, and method employs magnetic sections, catheters, and guidewires to modify tubular stentgrafts in-situ. One example application provides a more reliable way for surgeons to modify stentgrafts insitu to allow blood flow to continue to branching blood vessels that would otherwise be blocked by the stentgraft itself. One such method includes placing a tip section of the device in the desired location, deploying a stentgraft, placing a magnetic device inside the stentgraft, connecting the magnetic device to the tip section, and excising the portion of the stentgraft held between the magnet and the tip section. 1. An apparatus , comprising:a tip section having a proximal end and a distal end;a first guidewire extending coaxially through the tip section from the distal end to the proximal end; anda second guidewire attached to the tip section;wherein at least a portion of the tip section is magnetic.2. The apparatus of claim 1 , wherein the tip section is ogive-shaped.3. The apparatus in claim 1 , wherein the tip section comprises at least one rare earth magnet.4. The apparatus in claim 1 , wherein the tip section comprises material selected from a group consisting of neodymium claim 1 , cobalt claim 1 , iron claim 1 , samarium claim 1 , copper claim 1 , zirconium claim 1 , aluminum claim 1 , nickel claim 1 , and some combination thereof.5. The apparatus of claim 1 , wherein the first guidewire has a diameter of between 0.021 inches and 0.038 inches.6. The apparatus of claim 1 , wherein the second guidewire has a diameter of between 0.014 inches and 0.021 inches.7. The apparatus of claim 1 , wherein the second guidewire is attached to the side of the tip section.8. The apparatus of claim 1 , wherein the apparatus additionally comprises a first catheter and a second catheter claim 1 , wherein the first catheter surrounds the first guidewire and the second catheter surrounds the second guidewire.9. An apparatus claim 1 , comprising: ...

DEVICES AND METHODS FOR FORMING A FISTULA

Described here are devices, systems and methods for forming a fistula between two blood vessels. Generally, the systems may comprise a first catheter which may comprise a fistula-forming element. The fistula-forming element may comprise one or more electrodes, mechanical cutting elements, laser sources, or combinations thereof, and may be used to assist in fistula formation. In some instances, a system may comprise a second catheter, which may comprise a fistula-forming element. One or more of the catheters may comprise one or more markers, magnetic alignment elements, and/or one shape-changing elements. 1. A system for forming a fistula between two blood vessels comprising:a first catheter, comprising a catheter body, a lead wire and at least one alignment element, wherein the lead wire is moveable between a low-profile configuration and an extended position wherein at least a portion of the lead wire extends away from catheter body.2. The system of further comprising a second catheter.3. The system of wherein the second catheter comprises a recessed region.4. The system of wherein the recessed region is a pocket configured to receive at least a portion of lead wire when lead wire extends away from the catheter body of the first catheter.5. The system of wherein the second catheter comprises at least one alignment element claim 4 , and wherein the at least one alignment element of the first catheter and the at least one alignment element of the second catheter are configured to align the first catheter and the second catheter such that lead wire at least partially enters pocket when lead wire extends away from the catheter body of the first catheter.6. The system of wherein the pocket is formed in a nesting material housed at least partially within the catheter body of the second catheter.7. The system of wherein the pocket is formed in an electrode housed at least partially within the catheter body of the second catheter.8. The system of wherein the pocket is at ...

Cardiac treatment system

A cardiac device for implantation proximate an exterior of a heart, the cardiac device including an inflatable bladder including an inner wall and an outer wall, wherein the inner wall itself is more expandable than the outer wall itself such that the inflatable bladder itself is configured to deform substantially inwardly to exert localized pressure against a region of the heart when the inflatable bladder is positioned adjacent the region of the heart and inflated.

Method and apparatus for treating a patient by intentionally occluding a blood vessel, including method and apparatus for inducing weight loss in a patient by intentionally occluding the celiac artery

A method for inducing weight loss in a patient, the method comprising delivering an apparatus to a target area in the blood vessel. The apparatus includes a first portion for preventing migration of the apparatus from the target area within the blood vessel, and a second portion that remains implanted in the blood vessel after deployment of the apparatus at the target area in the blood vessel and is configured to selectively expand and contract to provide partial or full occlusion of the blood vessel. The method further comprises expanding the second portion of the apparatus to at least partially occlude the blood vessel, allowing a period of time to pass after deployment of the apparatus to the target area in the blood vessel, contracting the second portion, and removing at least the second portion of the apparatus from the blood vessel.

CARDIAC TREATMENT SYSTEM AND METHOD

Devices and methods for providing localized pressure to a region of a patient's heart to improve heart functioning, including: (a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and (b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart. 1. A cardiac implant for implantation around an exterior of a heart , the cardiac implant comprising:a jacket configured for implantation around ventricles of the heart, the jacket including an open top end configured to be positioned in an atrial-ventricular (A-V) groove of the heart; andan inflatable bladder comprising an inner wall and an outer wall, wherein the inner wall itself is more expandable than the outer wall itself, the inflatable bladder positioned adjacent to the jacket and located such that, when the top end is in the A-V groove, the inflatable bladder is positionable adjacent to a region of the heart.2. The cardiac implant of claim 1 , wherein the region of the heart comprises a mitral valve of the heart.3. The cardiac implant of claim 1 , wherein the jacket comprises a hem located around a perimeter of the open top end.4. The cardiac implant of claim 3 , wherein the inflatable bladder is located proximate the hem.5. The cardiac implant of claim 1 , wherein the inflatable bladder is attached to the jacket.6. The cardiac implant of claim 1 , wherein the jacket further comprises a bottom end configured to be positioned adjacent the apex of the heart.7. The cardiac implant of claim 6 , wherein the bottom end is an open bottom end claim 6 , and the bottom end is configured to be closed after ...

CARDIAC TREATMENT SYSTEM AND METHOD

Devices and methods for providing localized pressure to a region of a patient's heart to improve heart functioning, including: (a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and (b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart. 1an elongate barrel;a plurality of elongate members configured to extend along a length of the elongate barrel and extend distally from the elongate barrel, and being advanceable distally with respect to the elongate barrel, each of the elongate members comprising a distal end for attachment to a cardiac implant configured to be implanted around an exterior of a heart,a control mechanism configured to extend and retract the plurality of elongate members relative to the elongate barrel; anda handle assembly comprising a pistol grip configured to be held by a first hand of an operator while the operator uses a second hand to operate the control mechanism for the extension and retraction of the plurality of elongate members.. A delivery system for delivering an implantable cardiac device, the delivery system comprising: This application is a continuation of U.S. patent application Ser. No. 15/162,029 filed on May 23, 2016, which is a continuation of U.S. patent application Ser. No. 14/053,590 filed Oct. 14, 2013, which claims priority to U.S. Provisional Patent Application No. 61/713,351 filed on Oct. 12, 2012 by Hjelle et al., the contents of which are fully incorporated herein by reference.The present disclosure relates to medical devices for treating heart diseases and valvular dysfunction, including ...

Atraumatic Occlusion Balloons and Skirts, and Methods of Use Thereof

One aspect of the present invention relates to catheters that can be placed in or around bodily conduits to occlude or widen a biological lumen without imparting significant trauma to the lumen. In certain embodiments, the invention particularly relates to the use of a polymer composition which can be made to gel upon insertion into said balloon or skirt. In certain embodiments, the inflating viscous polymer composition is a liquid at room temperature and a gel at mammalian physiological temperature. In certain embodiments, the inflating viscous polymer composition comprises an optionally purified inverse thermosensitive polymer.

Apparatus and method for the ligation of tissue

A novel catheter-based system which ligates the left atrial appendage (LAA) on the outside of the heart, preferably using a combination of catheters and/or instruments, e.g., a guide catheter positioned inside the left atrial appendage which may assist in locating the left atrial appendage and/or assist in the optimal placement of a ligature on the outside of the appendage, and a ligating catheter and/or instrument outside the heart in the pericardial space to set a ligating element at the neck of the left atrial appendage.

Tissue ligation devices and controls therefor

Described here are devices for closing one or more tissues, and handles for controlling these devices. Generally, the devices described here comprise a snare loop assembly, wherein the snare loop assembly comprises a snare and a suture loop, and a handle for controlling the snare loop assembly. In some variations the snare loop assembly may comprise a retention member that may releasably connect the suture loop to the snare. In other variations the devices comprise one or more force-reducing suture locks to help prevent the suture loop from inadvertently disengaging from the snare loop assembly. In still other variations, the excess-suture management features. The handles described here may be configured to remove excess suture from a suture loop, and may also be configured to release the suture loop from the snare loop assembly.

Cardiac valve procedure methods and devices

Devices and methods for performing intravascular procedures without cardiac bypass include embodiments of temporary filter devices, temporary valves, and prosthetic valves. The temporary filter devices have a cannula which provides access for surgical tools for effecting repair of cardiac valves. The cannula may have filters which prevent embolitic material from entering the coronary arteries and aorta. The valve devices may also have a cannula for insertion of the valve into the aorta. The valve devices expand in the aorta to occupy the entire flow path of the vessel and operate to prevent blood flow and to permit flow through the valve. The prosthetic valves include valve fixation devices which secure the prosthetic valve to the wall of the vessel. The prosthetic valves are introduced into the vascular system in a compressed state, advanced to the site of implantation, and expanded and secured to the vessel wall.

Method and apparatus for resecting and replacing an aortic valve

A method and apparatus for delivering a device to a given location within a heart, the method and apparatus being adapted for: passing a first catheter through the left atrium of the heart, through the mitral valve and into the left ventricle, and passing a second catheter through the aorta toward the heart, one or the other of the first catheter and the second catheter, with the device attached thereto, forming a device-carrying assembly for engagement with the remaining catheter; causing the device-carrying assembly and the remaining catheter to engage one another so as to form a connection therebetween; and retracting one of the device-carrying assembly and the remaining catheter in a direction opposite to the other of the device-carrying assembly and the remaining catheter so as to position the device relative to the given location within the heart.

Apparatus for replacing a cardiac valve

A prosthetic heart valve in combination with a delivery assembly that includes a first elongate component that is movably disposed to a second elongate component. The delivery assembly has a temporary valve location relative to the delivery assembly to which the prosthetic heart valve can be releasably mounted in position and a spaced implantation location relative to the delivery assembly to which the prosthetic heart valve can also be releasably mounted in position. The prosthetic heart valve and delivery assembly combination is configurable with movement of the first elongate component relative to the second elongate component from a delivery state with the prosthetic heart valve mounted in the temporary location to an implantation state with the prosthetic heart valve repositioned from the temporary, location to the implantation location so that the prosthetic heart valve can subsequently be deployed from the implantation location.

Method and apparatus for resecting and replacing an aortic valve

Apparatus for resecting a diseased heart valve, the apparatus including: a body portion; a first handle and a second handle; a cutting blade; a set of retaining arms; a pass-off tool having a first attachment device configured to selectively engage the first handle attached to the body portion so as to allow placement of the second handle of the body portion adjacent to the diseased heart valve, and a controller tool, having a second attachment device at the distal end thereof, the second attachment device configured to selectively engage the second handle attached to the body portion so as to allow positioning of the body portion adjacent to the diseased heart valve, a cutting blade actuator configured to cause the cutting blade to selectively rotate, and a retaining arm actuator configured to selectively position the set of retaining arms from the contracted state to the expanded state.

Apparatus for replacing a cardiac valve

A delivery assembly for delivering a prosthetic heart valve can include a first elongate component and a second elongate component. The delivery assembly can include a temporary valve location to which the prosthetic heart valve can be releasably mounted and an implantation location to which the prosthetic heart valve can also be releasable mounted. The delivery assembly can move from a delivery state with the prosthetic heart valve mounted to the temporary location to an implantation state with the prosthetic heart valve repositioned from the temporary location to the implantation location. The prosthetic heart valve can subsequently be deployed from the implantation location. The position of the prosthetic heart valve relative to the first elongate component at the temporary location is different than a position of the prosthetic heart valve relative to the first elongate component at the implantation location.

Catheter apparatus and methodology for generating a fistula on-demand between closely associated blood vessels at a pre-chosen anatomic site in-vivo

The present invention provides catheter apparatus and catheterization methodology for generating an arteriovenous fistula or a veno-venous fistula on-demand between closely associated blood vessels and at a chosen anatomic site in-vivo. The catheter apparatus is preferably employed in pairs, each catheter of the pair being suitable for percutaneous introduction into and extension through a blood vessel. The catheterization methodology employs the catheter apparatus preferably in conjunction with conventional radiological techniques in order to place, verify, and confirm a proper alignment, orientation, and positioning for the catheters in-vivo prior to activating the perforation means for generating a fistula. The invention permits the generation of arteriovenous fistulae and veno-venous fistulae anatomically anywhere in the vascular system of a patient; nevertheless, the invention is most desirably employed in the peripheral vascular system as exists in the extremities of the body to aid in the treatment of the patient under a variety of different medical ailments and pathologies.

Apparatus and method for manipulating tissue

Apparatus for reconfiguring tissue, the apparatus comprising a shaft having a distal end and a proximal end; at least one effector mechanism movably mounted to the distal end of the shaft, each effector mechanism comprising at least one gripping element for gripping tissue to that effector mechanism, the at least one effector mechanism being configured to capture the gripped tissue against said shaft, at least one actuating mechanism mounted to the proximal end of the shaft, and at least one connection mechanism connecting the at least one actuating mechanism to the at least one effector mechanism, whereby a user may utilize the at least one actuating mechanism to actuate the at least one effector mechanism so as to reconfigure tissue.

Methods and devices to clear obstructions from medical tubes

A device for clearing obstructions from a medical tube, such as a chest tube, is disclosed in various embodiments. The device features a shuttle member that is magnetically coupled to a guide wire within a guide tube, through the guide- tube wall, so that translation of the shuttle member induces a corresponding translation of the guide wire within the guide tube, without penetrating or comprising the guide-tube wall. In this manner, when the guide tube is coupled to a medical tube where obstructions have formed, the guide wire and clearance member may be inserted into and withdrawn from the medical tube, via actuation of the shuttle member, to engage and help clear such obstructions from the medical tube without compromising the sterile field. Methods of clearing a medical tube of obstructions are also disclosed.

Method and apparatus for resecting and replacing an aortic valve

Tissue ligation devices and controls therefor

Methods and kits for treating lacerations and puncture wounds using inverse thermosensitive polymers

In certain embodiments, the present invention relates to methods and kits for treating wounds, comprising the step of introducing into said wound a composition comprising at least one optionally purified inverse thermosensitive polymer, wherein said at least one optionally purified inverse thermosensitive polymer forms a gel in said wound, thereby temporarily occluding said wound. In certain embodiments, the present invention relates to the aforementioned method wherein a wound to a blood vessel or a segment of the GI tract is occluded, thereby preventing exsanguination and/or septicemia. In other embodiments, the inventive methods and kits described herein may be used to ameliorate (e.g., fill) temporarily a defect in a biological lumen, thereby strengthening said defect, preventing rupture of, or maintaining, improving or optimizing fluid flow through said lumen.

Portable television controller with electronic switching

An electronic switch is provided for use in a battery-powered portable television receiver which eliminates power supply current drain when the television receiver is turned off. Coupled transistors are rendered conductive by means of either a clock or a manually switched input signal to provide a direct voltage battery output to television receiver circuitry. Also disclosed in an electronic switch combination for selectively controlling the audio output for the entire television receiver either manually or automatically.

Surgical coring system comprising a balloon catheter

A surgical coring system for off pump surgery, comprising a guide wire, a coring tool and a balloon catheter including various shaped balloon portions which are adapted to seal an apical hole in the left ventricle of a patient's heart and/or releasably secure the balloon catheter with respect to the apical hole.

Methods and apparatus for introducing a medical device into the body of a patient

An image guided robotic device is provided to perform a diagnostic or therapeutic medical procedure. In one embodiment, the robotic device includes an imaging machine, an actuator, and a controller for controlling the actuator. The robotic device may be configured to introduce a needle, a catheter, or a cannula into an anatomical structure. The device and its components may be sized for use as a portable device and/or operable using one hand of the operator.

Apparatus and method for manipulating tissue

Apparatus for reconfiguring tissue, the apparatus comprising a shaft (15) having a distal end and a proximal end; at least one effector mechanism (35) movably mounted to the distal end of the shaft (15), each effector mechanism (35) comprising at least one gripping element for gripping tissue to that effector mechanism, the at least one effector mechanism (35) being configured to capture the gripped tissue against said shaft (15), at least one actuating mechanism (45) mounted to the proximal end of the shaft (50), and at least one connection mechanism connecting the at least one actuating mechanism (45) to the at least one effector mechanism (35), whereby a user may utilize the at least one actuating mechanism (45) to actuate the at least one effector mechanism (35) so as to reconfigure tissue.

Apparatus and method for the ligation of tissue

A novel catheter-based system that ligates the left atrial appendage (LAA) on the outside of the heart, preferably using a combination of catheters and/or instruments, e.g., a guide catheter inserted into the interior of the left atrial appendage that may assist in locating the left atrial appendage and/or assist in the optimal placement of a ligature or constricting element on the outside of the appendage, and a ligating catheter and/or instrument outside the heart in the pericardial space to set the ligature or constricting element at the neck of the left atrial appendage.

Devices and methods for advancing a wire

Apparatus and method for reducing mitral regurgitation

Apparatus for reducing mitral regurgitation, including a bendable elongated body (50) adapted to be inserted into the coronary sinus (30) of a patient in the vicinity of the posterior leaflet (39) of the mitral valve (36), the elongated body (50) being adjustable between a first configuration adapted to be delivered into the coronary sinus (30) and a second configuration adapted to exert a force onto the posterior annulus (33). The body (50) includes a flexible spine having a proximal end and a distal end (52), and a flexible wire (54) mounted on the spine and having a distal end fixed to the spine proximate to the distal end of the spine, and having a proximal portion (56) extending from the proximal end of the spine. Axial movement of the wire (54) causes a change in the spine from the first configuration to the second configuration to exert the force on the posterior annulus (33) and thereby reduce mitral regurgitation.

Surgical coring system comprising a balloon catheter

A balloon catheter for use with a surgical coring system for off pump surgery, includes various shaped balloon portions which are adapted to seal an apical hole in the left ventricle of a patient's heart.

Devices and methods for fistula formation

Described here are devices and methods for forming a fistula between two vessels. In some instances, the fistula may be formed between a proximal ulnar artery and a deep ulnar vein. The fistula may be formed using an electrode, and may be formed with a first catheter placed in a first blood vessel and a second catheter placed in a second blood vessel. In some instances, access to the proximal ulnar artery may be achieved through a brachial artery, and access to the deep ulnar vein may be achieved through a brachial vein.

Doorbell actuated television security system

A video security system with intercom activated by means of a doorbell. The video input to a remote camera is automatically presented on the video display of a television receiver upon activation of the doorbell while audio from the intercom's speaker microphone is output through the television receiver's speaker system. Following a predetermined time interval after doorbell actuation, the system automatically turns off. If the television receiver is on when the doorbell is actuated, the system automatically provides video camera and intercom information at the television, reverting to the received television signal mode of operation upon user selection.

Devices for forming a fistula

Described here are devices, systems and methods for forming a fistula between two blood vessels. Generally, the systems may comprise a first catheter which may comprise a fistula-forming element. The fistula-forming element may comprise one or more electrodes, mechanical cutting elements, laser sources, or combinations thereof, and may be used to assist in fistula formation. In some instances, a system may comprise a second catheter, which may comprise a fistula-forming element. One or more of the catheters may comprise one or more markers, magnetic alignment elements, and/or one shape-changing elements.

Method and apparatus for treating a patient by intentionally occluding a blood vessel, including method and apparatus for inducing weight loss in a patient by intentionally occluding the celiac artery

Method and apparatus for improving mitral valve function

Isolation box for protecting reading material

A portable reverse isolation box (PRIB) for protecting an object from the environment and/or protecting a user from the object. The PRIB includes a housing comprising a container and a lid, wherein the container has structural integrity and at least a portion of the lid is transparent, and further wherein the housing forms an airtight and watertight isolation bay when the lid is mounted on the container; a port formed in the container; and a disposable flexible element mounted in the port in an airtight and watertight relationship, the flexible element being capable of assuming a concave configuration so as to permit a user to manipulate the object within the isolation bay without opening the lid.

Apparatus and method for manipulating tissue

Apparatus for reconfiguring tissue, the apparatus comprising a shaft (15) having a distal end and a proximal end; at least one effector mechanism (35) movably mounted to the distal end of the shaft (15), each effector mechanism (35) comprising at least one gripping element for gripping tissue to that effector mechanism, the at least one effector mechanism (35) being configured to capture the gripped tissue against said shaft (15), at least one actuating mechanism (45) mounted to the proximal end of the shaft (50), and at least one connection mechanism connecting the at least one actuating mechanism (45) to the at least one effector mechanism (35), whereby a user may utilize the at least one actuating mechanism (45) to actuate the at least one effector mechanism (35) so as to reconfigure tissue.

Apparatus and method for reducing mitral regurgitation

Apparatus for reducing mitral regurgitation, by applying a force to the wall of the coronary sinus so as to force the posterior leaflet anteriorly and thereby reduce mitral regurgitation.

vascular stent devices and methods

a presente invenção refere-se a dispositivos, sistemas e métodos para a canulação de um vaso. geralmente, o método pode compreender o avanço de um stent em um primeiro vaso e a implantação do stent no primeiro vaso para manter aberta uma ou mais válvulas. isto pode permitir o fluxo sanguíneo retrógrado através do vaso sanguíneo na vasculatura periférica e ajudar na canulação do vaso sanguíneo.

Apparatus and method for manipulating tissue

Apparatus for reconfiguring tissue, the apparatus comprising a shaft (15) having a distal end and a proximal end; at least one effector mechanism (35) movably mounted to the distal end of the shaft (15), each effector mechanism (35) comprising at least one gripping element for gripping tissue to that effector mechanism, the at least one effector mechanism (35) being configure d to capture the gripped tissue against said shaft (15), at least one actuatin g mechanism (45) mounted to the proximal end of the shaft (50), and at least o ne connection mechanism connecting the at least one actuating mechanism (45) to the at least one effector mechanism (35), whereby a user may utilize the at least one actuating mechanism (45) to actuate the at least one effector mechanism (35) so as to reconfigure tissue.

Method and apparatus for improving mitral valve function

Apparatus for introducing a medical device into the body of a patient

Vascular stent devices and methods

Described here are devices, systems, and methods for cannulating a vessel. Generally, the method may comprise advancing a stent into a first vessel and deploying the stent in the first vessel to hold open one or more valves. This may permit retrograde blood flow through the blood vessel in peripheral vasculature and aid in cannulation of the blood vessel.

Pericardial retractor

Method and apparatus for reducing mitral regurgitation

A method and device (157) for reducing mitral regurgitation. An elongated body is positioned in a coronary sinus of a patient in a vicinity of a heart mitral valve posterior leaflet (39). The body is adapted to straighten a natural curvature of at least a portion of the coronary sinus in the vicinity of the posterior leaflet to move a posterior annulus (33) anteriorly, which in turn moves the posterior leaflet (39) anteriorly, thereby to improve leaflet coaptation.

Methods and devices to clear obstructions from medical tubes

A device for clearing obstructions from a medical tube, such as a chest tube, is disclosed in various embodiments. The device features a shuttle member that is magnetically coupled to a guide wire within a guide tube, through the guide-tube wall, so that translation of the shuttle member induces a corresponding translation of the guide wire within the guide tube, without penetrating or compromising the guide-tube wall. In this manner, when the guide tube is coupled to a medical tube where obstructions have formed, the guide wire and clearance member may be inserted into and withdrawn from the medical tube, via actuation of the shuttle member, to engage and help clear such obstructions from the medical tube without compromising the sterile field. Methods of clearing a medical tube of obstructions are also disclosed.

Cardiac treatment system and method

Apparatus and method for the ligation of tissue

A novel catheter-based system which ligates the left atrial appendage (LAA) on the outside of the heart, preferably using a combination of catheters and/or instruments, e.g., a guide catheter positioned inside the left atrial appendage which may assist in locating the left atrial appendage and/or assist in the optimal placement of a ligature on the outside of the appendage, and a ligating catheter and/or instrument outside the heart in the pericardial space to set a ligating element at the neck of the left atrial appendage.