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Применить Всего найдено 6. Отображено 6.
29-09-2005 дата публикации

Testing multiple fluid samples with multiple biopolymer arrays

Номер: US2005214854A1
Автор: DAHM SUEANN C, SCHLEIFER ARTHUR, SCHEMBRI CAROL T, AMORESE DOUGLAS A, DAHM SUEANN C., SCHEMBRI CAROL T., AMORESE DOUGLAS A.
Принадлежит:

A method of testing multiple fluid samples with multiple biopolymer arrays. A cover is assembled to a contiguous substrate carrying on a first side, multiple arrays each with multiple regions of biopolymers linked to the substrate, such that the cover and the substrate together form a plurality of chambers each containing a biopolymer array and each being accessible through its own port. Multiple fluid samples are introduced into respective chambers through a port of each such that the fluid samples contact respective arrays. A binding pattern of the arrays is observed. An apparatus and kit useful in such methods, are also provided.

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Номер записи: 1
24-07-2007 дата публикации

Testing multiple fluid samples with multiple biopolymer arrays

Номер: US0007247497B2
Автор: SueAnn C. Dahm, Arthur Schleifer, Carol T. Schembri, Douglas A. Amorese, DAHM SUEANN C, SCHLEIFER ARTHUR, SCHEMBRI CAROL T, AMORESE DOUGLAS A, DAHM SUEANN C., SCHEMBRI CAROL T., AMORESE DOUGLAS A.
Принадлежит: Agilent Technologies, Inc., AGILENT TECHNOLOGIES INC, AGILENT TECHNOLOGIES, INC.

A method of testing multiple fluid samples with multiple biopolymer arrays. A cover is assembled to a contiguous substrate carrying on a first side, multiple arrays each with multiple regions of biopolymers linked to the substrate, such that the cover and the substrate together form a plurality of chambers each containing a biopolymer array and each being accessible through its own port. Multiple fluid samples are introduced into respective chambers through a port of each such that the fluid samples contact respective arrays. A binding pattern of the arrays is observed. An apparatus and kit useful in such methods, are also provided.

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Номер записи: 2
04-06-2002 дата публикации

Testing multiple fluid samples with multiple biopolymer arrays

Номер: US0006399394B1
Автор: SueAnn C. Dahm, Arthur Schleifer, Carol T. Schembri, Douglas A. Amorese, DAHM SUEANN C, SCHLEIFER ARTHUR, SCHEMBRI CAROL T, AMORESE DOUGLAS A, DAHM SUEANN C., SCHEMBRI CAROL T., AMORESE DOUGLAS A.
Принадлежит: Agilent Technologies, Inc., AGILENT TECHNOLOGIES INC, AGILENT TECHNOLOGIES, INC.

A method of testing multiple fluid samples with multiple biopolymer arrays. A cover is assembled to a contiguous substrate carrying on a first side, multiple arrays each with multiple regions of biopolymers linked to the substrate, such that the cover and the substrate together form a plurality of chambers each containing a biopolymer array and each being accessible through its own port. Multiple fluid samples are introduced into respective chambers through a port of each such that the fluid samples contact respective arrays. A binding pattern of the arrays is observed. An apparatus and kit useful in such methods, are also provided.

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Номер записи: 3
26-05-2009 дата публикации

Method of testing multiple fluid samples with multiple biopolymer arrays

Номер: US0007537936B2
Автор: SueAnn C. Dahm, Arthur Schleifer, Carol T. Schembri, Douglas A. Amorese, DAHM SUEANN C, SCHLEIFER ARTHUR, SCHEMBRI CAROL T, AMORESE DOUGLAS A, DAHM SUEANN C., SCHEMBRI CAROL T., AMORESE DOUGLAS A.
Принадлежит: Agilent Technologies, Inc., AGILENT TECHNOLOGIES INC, AGILENT TECHNOLOGIES, INC.

A method of testing multiple fluid samples with multiple biopolymer arrays. A cover is assembled to a contiguous substrate carrying on a first side, multiple arrays each with multiple regions of biopolymers linked to the substrate, such that the cover and the substrate together form a plurality of chambers each containing a biopolymer array and each being accessible through its own port. Multiple fluid samples are introduced into respective chambers through a port of each such that the fluid samples contact respective arrays. A binding pattern of the arrays is observed. An apparatus and kit useful in such methods, are also provided.

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Номер записи: 4
03-06-1998 дата публикации

Nucleic acid signal amplification method

Номер: GB2319839A
Автор: Douglas J Dellinger, Mark A Troll, Sueann C Dahm
Принадлежит: Hewlett Packard Co

A signal amplification method for detecting a target nucleic acid analyte 3 having a homopolymeric region 7 and a target sequence 5, the method comprising: (a) contacting an analyte under hybridizing conditions with a multiplicity of reporter probes 9, each probe including a signal region and an oligonucleotide sequence which is complementary to, and capable of forming a stable hybrid 15 with the analyte 3 homopolymeric region; and (b) forming an analyte capture probe hybrid 15 by contacting the analyte target sequence with a capture probe 11 under hybridizing conditions. The detection of RNA with a fluorescein-labelled poly U reporter probe is illustrated.

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Номер записи: 5
29-08-2000 дата публикации

Signal enhancement method and kit

Номер: US6110682A
Автор: Douglas J. Dellinger, Mark A. Troll, SueAnn C. Dahm
Принадлежит: AGILENT TECHNOLOGIES INC

The invention discloses and claims a signal amplification method for detecting a target nucleic acid analyte having a homopolymeric region and a target sequence. The method comprises (a) contacting an analyte under hybridizing conditions with a multiplicity of reporter probes, each probe including a signal region and an oligonucleotide sequence which is complementary to, and capable of forming a stable hybrid with the analyte homopolymeric region; and (b) forming an analyte:capture probe hybrid by contacting the analyte target sequence with a capture probe under hybridizing conditions.

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Номер записи: 6