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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Применить Всего найдено 2. Отображено 2.
10-09-2014 дата публикации

Calcium-affinity nanoparticle with Pamidronate disodium-modified Brij78 as key component and preparation method thereof

Номер: CN104027811A
Автор: YAN WEILI, ZHANG JIABIN, SONG HELIANG, LIU XINRONG, YAO PENG, DENG TONGMING, LIANG HUAN, WANG QIAN, WANG KANG
Принадлежит:

The invention relates to a calcium-affinity nanoparticle with Pamidronate disodium-modified Brij78 as a key component and a preparation method thereof. The key component is a surfactant with a calcium affinity effect and is prepared by reacting a series of Brij compounds with p-methyl benzene sulfonic chloride to prepare an intermediate and then reacting the intermediate with bisphosphonate. According to the invention, good surface activity of the series of Brij compounds is retained, and calcium affinity capability of the series of Brij compounds is improved at the same time. The preparation method has the advantages of reliable principles, simple steps, easy operation, high security of used reactants and solvents and small pollution to the environment. The Pamidronate disodium-modified Brij78 has good high temperature stability and chemical stability; and a variety of drug-loaded nanoparticles prepared from the Pamidronate disodium-modified Brij78 have calcium affinity and bone targeting ...

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Номер записи: 1
23-06-2023 дата публикации

Method for detecting sensitization of adsorption resin

Номер: CN116298227A
Автор: DONG FAN, HUANG GUANGHUI, DENG TONGMING
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The invention provides a method for detecting sensitization of adsorption resin. The method comprises the following steps: acquiring RBL-2H3 cells to be excited; rBL-2H3 cells to be excited are respectively set as a positive control group, a negative control group, a standard substance control group and a group to be detected, a substance in the positive control group is a positive control substance, a substance in the negative control group is a buffer solution, a substance in the standard substance control group is standard substance adsorption resin and a buffer solution, and a substance in the group to be detected is a standard substance adsorption resin. Substances in the to-be-detected group are to-be-detected adsorption resin and a buffer solution; respectively detecting the OD (optical density) value of the beta-hexosaminidase in each group; if the OD value of the beta-hexosaminidase in the positive control group and the OD value of the beta-hexosaminidase in the negative control ...

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Номер записи: 2