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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 17. Отображено 17.
08-07-2015 дата публикации

Hexahydro-1H-pyrrolo[3,4-d]pyrimidine compound and preparation method thereof

Номер: CN104761557A
Автор: MAO LONGFEI, LI WEI, MAO SHEN, JIANG YUQIN, XU GUIQING, DONG WENPEI, JIANG TAO, SHEN JIAXUAN
Принадлежит:

The invention discloses a hexahydro-1H-pyrrolo[3,4-d]pyrimidine compound and a preparation method thereof. The invention relates to the technical field of organic synthesis. The key point of the technical scheme of the invention is that the hexahydro-1H-pyrrolo[3,4-d]pyrimidine compound has a following structure shown in the specification, wherein R1 is H, methyl, ethyl, isopropyl, cyclopropylmethyl, methyletherethyl, isobutyl or benzyl; R2 is H or cyclopropylmethyl. The invention also discloses the preparation method of the hexahydro-1H-pyrrolo[3,4-d]pyrimidine compound. The preparation method provided by the invention is simple and feasible. The raw materials are cheap and easily available. The method also has the advantages of high reaction efficiency and good repeatability.

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Номер записи: 1
25-03-2015 дата публикации

Preparation method of high-purity troxerutin

Номер: CN104447914A
Автор: TAN XUXIA, LI SHINING, JIANG YUQIN, MAO LONGFEI, QI QINGHUA, DONG WENPEI, ZHANG WEIWEI, XU GUIQING, LI WEI
Принадлежит:

The invention discloses a preparation method of high-purity troxerutin. According to the preparation method of the high-purity troxerutin, the synthesis and refining processes of the troxerutin are improved; sodium methoxide or sodium ethoxide is selected as a catalyst, supercritical CO2 is selected for extraction and crystallization refining of the troxerutin, and finally, the troxerutin of which the yield and the purity both are greatly improved in contrast with a traditional process can be obtained.

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Номер записи: 2
23-06-2023 дата публикации

Shallow soft soil layer exploration sampling device

Номер: CN116296582A
Автор: LYU ZICHUAN, YANG GUANG, ZOU JINMING, DONG WENPEI, JIANG WEIXIN, YU XIAOLONG
Принадлежит:

The invention discloses a soft soil shallow layer exploration sampling device which comprises a barrel and a pressure sleeve, the barrel and the pressure sleeve are equal in outer diameter size, a limiting plate is arranged on the outer side of the barrel, a cone is arranged at the lower end of the pressure sleeve, a mounting cavity is formed in the upper end of the pressure sleeve, and the end, close to the pressure sleeve, of the barrel is of a closed structure. One end of the sampling pipe is provided with a limiting part, the end is provided with a positioning sleeve located in the mounting cavity, a sampling pipe is arranged in the positioning sleeve, the middle of the positioning sleeve is provided with a power part for driving the sampling pipe to horizontally stretch and slide, the sampling pipe is of a hollow structure, one end of the sampling pipe is in sliding connection with the positioning sleeve, and the other end of the sampling pipe is mounted on the power part. The sampling ...

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Номер записи: 3
09-09-2015 дата публикации

Method for purifying dehydroandrographolide succinate

Номер: CN104892552A
Автор: XU GUIQING, ZHAO LIANGLIN, JIANG YUQIN, LI SHINING, MAO LONGFEI, DONG WENPEI, LI WEI
Принадлежит:

The invention discloses a method for purifying dehydroandrographolide succinate. According to the invention, a solution, of hydrochloric acid or acetic acid, with a pH value of 5-6 is selected as a dispersant during dispersion and crystallization of dehydroandrographolide succinate; and extraction, crystallization and refining of dehydroandrographolide succinate are carried out with supercritical CO2. The obtained product has a yield more 80% and purity more than 98%.

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Номер записи: 4
23-09-2015 дата публикации

Tetrahydro imidazo thieno hydrochloride compound with biological activity and preparing method thereof

Номер: CN104926839A
Автор: MAO LONGFEI, XU GUIQING, LI WEI, JIANG YUQIN, JIANG TAO, DONG WENPEI, SHEN JIAXUAN
Принадлежит:

The invention discloses a tetrahydro imidazo thieno hydrochloride compound with the biological activity and a preparing method thereof and belongs to the technical field of drug synthesis. The tetrahydro imidazo thiophene pyridine hydrochloride compound with the biological activity is characterized by being provided with the following structure (please see the formula in the specification), and R represents formonitrile phenyl, or tertiary butyl, or phenyl, or trifluoromethyl, or p-chlorophenyl or meta-methoxyphenyl. The invention further discloses the preparing method of the tetrahydro imidazo thiophene pyridine hydrochloride compound with the biological activity. A series of tetrahydro imidazo thiophene pyridine hydrochloride compounds with the biological activity is synthesized through the new method, the reaction process is easy to operate and implement, raw materials are low in price and easy to obtain, the reaction efficiency is high, repeatability is good, and the biological activity ...

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Номер записи: 5
05-08-2015 дата публикации

Oxazole compound with anti-fungal activity, preparation method of oxazole compound and application of oxazole compound

Номер: CN104817549A
Автор: LI WEI, LI SHINING, MAO LONGFEI, JIANG YUQIN, XU GUIQING, DONG WENPEI, SHEN JIAXUAN, JIANG TAO
Принадлежит:

The invention discloses an oxazole compound with anti-fungal activity, a preparation method of the oxazole compound and an application of the oxazole compound to tobacco powdery mildew original fungi or cotton anthracnose original fungi prevention, and belongs to the technical field of organic synthesis. The technical scheme mainly includes that the oxazole compound with the anti-fungal activity is provided with a structure shown in the instruction, R1 refers to propiono, isopropyl, acetyl, ethyl or methyl, and R2 refers to dimethylamino or methylamine. Five oxazole compounds with the anti-fungal activity are synthesized by the novel method, the preparation process is simple in technology and easy to control, target product yield is high, repeatability is fine, and the five prepared oxazole compounds with the anti-fungal activity have a certain prevention function for tobacco powdery mildew original fungi or cotton anthracnose original fungi.

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Номер записи: 6
30-09-2015 дата публикации

Method for synthesizing 1,2,3-triazole compound through three components in one pot

Номер: CN104945341A
Автор: JIANG YUQIN, ZHAO YARU, HE XING, TAN XUXIA, ZHAO LIANGLIN, DONG WENPEI, XU GUIQING, LI WEI
Принадлежит:

The invention discloses a method for synthesizing 1,2,3-triazole compound through three components in one pot, and belongs to the technical field of synthesis of the 1,2,3-triazole compound. According to the technical scheme, the method is characterized by including the steps of sequentially adding sodium azide and catalyst to solvent, namely, dimethyl sulfoxide, in a reaction container, sequentially adding dimethyl sulfoxide, DBU and aldehyde compound, and stirring the reaction mixture at the temperature of 60 DEG C to 95 DEG C to obtain the 1,2,3-triazole compound. The triazole compound is synthesized through three-component coupling reaction; compared with a traditional method, the reaction steps are reduced, the postprocessing process is simplified, the process is simple, operation is easy and convenient, reaction is gentle, the reaction time is short, efficiency is high, and the method is suitable for large-scale production.

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Номер записи: 7
01-04-2015 дата публикации

4-methoxy methyl acetoacetate preparation method

Номер: CN104478719A
Автор: MAO LONGFEI, LI WEI, KOU LIDONG, JIANG YUQIN, DONG WENPEI, MAO ALONG, CHEN XIAOHUA, WAN ZHONG
Принадлежит:

The invention discloses a 4-methoxy methyl acetoacetate preparation method. The 4-methoxy methyl acetoacetate preparation method comprises the following steps of adding a solvent tetrahydrofuran into a reaction kettle and leading inert gas into the reaction kettle, setting the internal temperature of the reaction kettle to be 15 DEG C to 25 DEG C, adding industrial sodium hydride and a metal alkaline compound in a stirring state, then adding the solvent tetrahydrofuran, dropwise adding mixed liquid of methyl alcohol and methyl-4-chloroacetoacetate at the temperature of lower than 20 DEG C to perform reaction for 4-6 hours, rising the temperature to be 20 DEG C to 25 DEG C to continue to react for 4-15 hours, reducing the system temperature to be 6 DEG C to 10 DEG C after TLC detection reaction is completed, adding a hydrochloric acid solution with molar concentration of 2 mol/L to regulate the pH of a system to be 5 to 7, performing standing and laying, concentrating and spin-drying upper-layer ...

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Номер записи: 8
26-08-2015 дата публикации

Phenyl-ester spiro-pyrrolidine compound and preparation method therefor

Номер: CN104860954A
Автор: MAO LONGFEI, KOU LIDONG, LI WEI, JIANG YUQIN, DONG WENPEI, JIANG TAO, SHEN JIAXUAN, LI YOU
Принадлежит:

The invention discloses a phenyl-ester spiro-pyrrolidine compound and a preparation method therefor and belongs to the technical field of synthesis of spiro-compounds. The key point of the technical scheme of the invention is as follows: the phenyl-ester spiro-pyrrolidine compound has the following structure as shown in the description, wherein R is -COOCH3, -COOCH2CH3, -COO(CH2)2CH3 or -COOCH(CH3)2. The invention also discloses a preparation method for the phenyl-ester spiro-pyrrolidine compound. According to the phenyl-ester spiro-pyrrolidine compound and the preparation method therefor, a variety of phenyl-ester spiro-pyrrolidine compounds are synthesized by the novel method, and the preparation process is simple in process, easy to control, high in target product yield and good in repeatability.

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Номер записи: 9
16-09-2015 дата публикации

5,6,7,8-tetrahydropyrido[3,4-d] pyrimidine compound with bioactivity as well as preparation method and application thereof

Номер: CN104910158A
Автор: MAO LONGFEI, XU GUIQING, LI WEI, JIANG YUQIN, DONG WENPEI, JIANG TAO, SHEN JIAXUAN
Принадлежит:

The invention discloses a 5,6,7,8-tetrahydropyrido[3,4-d] pyrimidine compound with a bioactivity as well as a preparation method and an application thereof, and belongs to the technical field of synthesis for a compound with an anti-tumour activity. The essential of the technical scheme of the invention is as follows: the 5,6,7,8-tetrahydropyrido[3,4-d] pyrimidine compound with the bioactivity has a structure specified in the description, wherein R1 is ethyl formate, ethylamine methyl group, methylamine formyl group, dimethylamino formyl group, pyridine-3-formamidino formyl group, pyridine formyl group or anilino formyl group, and R2 is hydrogen or benzyl group. The invention further discloses a preparation method for the 5,6,7,8-tetrahydropyrido[3,4-d] pyrimidine compound with the bioactivity and an application thereof in preparation for an anti-breast tumour medicine. The preparation process disclosed by the invention is simple in process, easy to control, high in target product yield ...

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Номер записи: 10
09-09-2015 дата публикации

Preparation method of p-aminophenylethylamine

Номер: CN104892427A
Автор: LI WEI, KOU LIDONG, MAO LONGFEI, WU DOUCAN, JIANG YUQIN, XU GUIQING, DONG WENPEI, JIANG TAO, SHEN JIAXUAN, WAN ZHONG
Принадлежит:

The invention discloses a preparation method of p-aminophenylethylamine, belonging to the technical field of organic synthesis. The technical scheme is as follows: the preparation method comprises the following steps: by using p-nitrophenylethanol as a raw material, carrying out catalytic hydrogenation to reduce the para-position nitro groups of the p-nitrophenylethanol into amino groups, carrying out Boc acid anhydride protection on the para-position nitro groups, carrying out substitution reaction on hydroxy groups with sulfonyl chloride compounds to obtain sulfonic acid compounds, aminating, and finally, removing Boc groups to obtain the p-aminophenylethylamine. The preparation process is simple and easy to implement, and has the advantages of cheap and accessible raw materials, higher reaction efficiency and favorable repetitiveness.

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Номер записи: 11
01-04-2015 дата публикации

Method for preparing troxerutin by adopting self-suction type stirred autoclave

Номер: CN104478972A
Автор: JIANG YUQIN, HE XING, QI QINGHUA, ZHAO YARU, ZHANG DAN, ZHANG WEIWEI, DONG WENPEI, MAO LONGFEI, XU GUIQING, LI WEI
Принадлежит:

The invention discloses a method for preparing troxerutin by adopting a self-suction type stirred autoclave. The method comprises the following steps: adding raw materials namely rutin, ethylene oxide, a solvent namely methanol and a catalyst namely natural weakly-alkaline high-molecular compound chitosan into a self-suction type stirred autoclave, starting a digital control instrument, setting a temperature to be 70-90 DEG C, regulating a voltage to be 100V, setting a rotating speed to be 1000r/min, stirring and heating to reach a set temperature, and reacting for 3-6 hours; and stopping stirring after reaction is ended, rapidly cooling by using cold water, shutting down the digital control instrument, opening a reaction kettle, pouring out reaction liquid, adjusting a pH value of the poured reaction liquid to be 5-6 by using hydrochloric acid, performing suction filtration, adding a crystal seed into the reaction liquid subjected to suction filtration, standing for later crystallization ...

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Номер записи: 12
08-07-2015 дата публикации

Hexahydropyrrolo[3,4-c]pyrrolidine compound and preparation method thereof

Номер: CN104761559A
Автор: KOU LIDONG, MAO LONGFEI, LI WEI, KOU YUPENG, JIANG YUQIN, DONG WENPEI, JIANG TAO, SHEN JIAXUAN
Принадлежит:

The invention discloses a phenyl ester spiro pyrrolidine compound and a preparation method thereof, belonging to the technical field of synthesis of spiro compounds. According to the key points of the technical scheme, the phenyl ester spiro pyrrolidine compound has the following structure, wherein the structural formula is as shown in the specification; R refers to -COOCH3, -COOCH2CH3, -COO(CH2)2CH3 or -COOCH(CH3)2. The invention also discloses a preparation method of the phenyl ester spiro pyrrolidine compound. Multiple phenyl ester spiro pyrrolidine compounds are synthesized by virtue of a novel method, and in the preparation process, the process is simple and easy to control, the product yield of the target product is high, and the repeatability is high.

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Номер записи: 13
05-05-2023 дата публикации

Self-assembled core-based nanofiber peptide PEG-Q11T as well as preparation method and application of self-assembled core-based nanofiber peptide PEG-Q11T

Номер: CN116063402A
Автор: DONG WENPEI, CHEN MENGTING, XU JIAQI, XU LINGYUN, JIANG TAO, CHEN CHANGPO
Принадлежит:

The invention belongs to the technical field of biological materials, and particularly relates to a self-assembly core-based nanofiber peptide PEG-Q11T peptide as well as a preparation method and application thereof, and the structure of the PEG-Q11T peptide is Am-QQEFQFQFKQQGSGSRTRTR-mPEG. The natural base thymine is used for expanding the self-assembled fiber peptide chain Q11 for the first time, then PEG modification is performed to obtain the self-assembled core-based nanofiber peptide PEG-Q11T, the obtained self-assembled core-based nanofiber peptide PEG-Q11T can be self-assembled into a nano-scale fiber structure in a PBS buffer solution, the nano-scale fiber structure is used for loading cyclic dinucleotide 2 ', 3'-cGAMP, the cytotoxicity is low, the biocompatibility is good, and the self-assembled core-based nanofiber peptide PEG-Q11T can be used for loading cyclic dinucleotide 2 ', 3'-cGAMP. Moreover, the loading dose of the cyclic dinucleotide 2 ', 3'-cGAMP can be effectively ...

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Номер записи: 14
22-04-2015 дата публикации

Decoloration and deodorization technology for waste plastic cracking crude oil

Номер: CN104531210A
Автор: LI WEI, ZHANG DANDAN, MAO LONGFEI, JIANG YUQIN, DONG WENPEI, MAO ALONG, CHEN XIAOHUA, WAN ZHONG
Принадлежит:

The invention discloses a decoloration and deodorization technology for waste plastic cracking crude oil, and belongs to the technical field of waste plastic recycling. According to the technical scheme, the decoloration and deodorization technology for the waste plastic cracking crude oil is characterized in that concentrated sulfuric acid with the mass concentration being 98% is added in the waste plastic cracking crude oil, stirring is conducted for 2-4 h at the temperature of 40-50 DEG C, standing is carried out, black impurities on a lower layer are drained away, an alkaline solution is added in liquid supernatant to adjust the pH to be 6-7, then cationic flocculant and a decolorising agent are added, the temperature rises to 60-70 DEG C, reaction is conducted for 4-6 h, suction filtration is conducted, an antioxidant is added in a filter solution, and plastic oil meeting the standard can be obtained. According to the decoloration and deodorization technology, high-quality products ...

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Номер записи: 15
08-07-2015 дата публикации

1,1-dioxo-4H-benzo[1,2,4]-thiadiazine hydrochloride compound and preparation method thereof

Номер: CN104761514A
Автор: ZHANG DANDAN, MAO LONGFEI, LI WEI, JIANG YUQIN, XU GUIQING, DONG WENPEI, JIANG TAO, SHEN JIAXUAN
Принадлежит:

The invention discloses a 1,1-dioxo-4H-benzo[1,2,4]-thiadiazine hydrochloride compound and a preparation method thereof, belonging to the technical field of organic synthesis. The technical scheme has the key point as follows: the 1,1-dioxo-4H-benzo[1,2,4]- thiadiazine hydrochloride compound has the structure as shown in the specification, wherein R is H, -CH3 or -C2H5. The invention also discloses the preparation method of the 1,1-dioxo-4H-benzo[1,2,4]-thiadiazine hydrochloride compound. The preparation method is simple, convenient and easy to operate, relatively high in reaction efficiency and relatively good in repeatability, and raw materials are cheap and available.

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Номер записи: 16
30-09-2015 дата публикации

Acetylacetone copper (II) catalytic synthesis method for 1,2,3 triazole chemical compounds

Номер: CN104945340A
Автор: JIANG YUQIN, LI XINGFENG, GUO NIU, HE XING, DONG WENPEI, MAO LONGFEI, XU GUIQING, LI WEI
Принадлежит:

The invention discloses an acetylacetone copper (II) catalytic synthesis method for 1,2,3 triazole chemical compounds, and belongs to the field of the synthetic technology of the 1,2,3 triazole chemical compounds. According to the technical scheme, azide and end group compound serve as raw materials, the acetylacetone copper (II) serves as a catalyzer, water serves as a solvent, stirring and reacting are conducted, complete reaction of the raw materials is monitored by TLC, ethyl acetate is added to extract a reaction product, water phase and organic phase are filtered at the same time, a filter cake is cleaned by using the ethyl acetate to obtain the catalyzer, namely, the acetylacetone copper (II) to be recycled repeatedly, and skimming is conducted on filter liquor to obtain the organic phase of the 1,2,3 triazole chemical compound. The catalyzer is cheap, the preparation method is simple, the catalytic efficiency is high, reutilization can be achieved, the catalyzer is reproducible, ...

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Номер записи: 17