13-05-2021 дата публикации
Номер: US20210137877A1
Принадлежит:
The disclosed embodiments provide chemical compositions and methods for inducing sleep, the compositions comprising active ingredients of (i) major cannabinoids, (ii) minor cannabinoids, and (iii) sleep-regulating compound(s) comprising at least 1 mg of melatonin. The major cannabinoids comprise 15 to 135 mg of CBD, up to 5 mg of Δ9-THC, where the ratio of the CBD to the Δ9-THC is at least 10 to 1. The minor cannabinoids comprise up to 5 mg of CBDv, up to 15 mg of CBN, up to 5 of CBGa, up to 5 mg of CBG, and 0.1 to 5 mg of CBC, where a total amount of the minor cannabinoids is at least 1 mg, and a ratio of the CBD to the minor cannabinoids is at least 5 to 1. 1. A composition for inducing sleep in a human , wherein a single dose of the composition comprises: [ 15 to 135 mg of cannabidiol (CBD);', 'up to 5.0 mg of Δ9-tetrahydrocannabinol (Δ9-THC);', 'wherein a mass ratio of the CBD to the Δ9-THC is at least 10:1;, '(i) major cannabinoids comprising, up to 5.0 mg of cannabidivarin (CBDv);', 'up to 15 mg of cannabinol (CBN);', 'up to 5.0 of cannabigerolic acid (CBGa);', 'up to 5.0 mg of cannabigerol (CBG);', {'b': '0', '. 1 to 5.0 mg of cannabichromene (CBC);'}, 'wherein a total amount of the minor cannabinoids is at least 1 mg;', 'wherein a mass ratio of the CBD to the minor cannabinoids is at least 5 to 1;, '(ii) minor cannabinoids comprising, at least 1 mg of melatonin;', 'wherein a mass ratio of the CBD to the melatonin is at least 15 to 1;, '(iii) one or more sleep-regulating compounds comprising], '(a) active ingredients, wherein the active ingredients comprise(b) a carrier for the single dose of the composition, wherein the active ingredients are disposed in the carrier.2. The composition of claim 1 , wherein the major cannabinoids comprise at least 25 mg of CBD.3. The composition of claim 2 , wherein the major cannabinoids comprises not greater than 120 mg CBD.4. The composition of claim 1 , wherein the one or more sleep-regulating compounds comprise 2.0 to 4.0 ...
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