02-01-2020 дата публикации
Номер: US20200003754A1
Принадлежит:
A bioelectrochemical sensor utilizing a nanoporous gold electrode. The bioelectrochemical sensor is suitable for measuring redox in biologic media while having increased resistance to biofouling as compared to conventional electrodes such as planar gold electrodes, due to greater exposed surface area of the three-dimensional ligature structure defining the nanopores. The nanopores have a pore size of 5-100 nm, preferably with an average pore size of less than 50 nm, and more preferably with an average pore size of less than 20 nm. 1. A bioelectrochemical sensor , comprising: a plurality of gold coated strips;', 'an etched gold leaf disposed over a surface of the plurality of gold coated strips;', 'a strip of TEFLON tape disposed over the etched gold leaf, the TEFLON tape having a hole therethrough positioned over the etched gold leaf; and, 'a first electrode including a nanoporous precious metal, the nanoporous precious metal of the first electrode being nanoporous gold, the first electrode including'}a reference electrode.2. (canceled)3. The bioelectrochemical sensor of claim 1 , the pores of the nanoporous precious metal of the first electrode having a pore size of 100 nm or less.4. The bioelectrochemical sensor of claim 3 , the nanoporous precious metal of the first electrode having an average pore size of less than 50 nm.5. The bioelectrochemical sensor of claim 3 , the nanoporous precious metal of the first electrode having an average pore size of less than 20 nm.6. The bioelectrochemical sensor of claim 1 , further comprising a counter electrode.7. The bioelectrochemical sensor of claim 1 , the reference electrode being a silver/silver chloride electrode.8. The bioelectrochemical sensor of claim 6 , the counter electrode being platinum.9. The bioelectrochemical sensor of claim 1 , in combination with a block having a microfluidic channel therein claim 1 , the microfluidic channel including a portion aligned with an exposed nanoporous region of the first ...
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