Interactive modulator of disheveled protein and beta-catenins interactive function

Method for calculating starting speed of channel deposit blocks under the action of hyperconcentrated flow

The invention relates to an application method of a hydraulic mathematical model, in particular to a method for calculating starting speed of channel deposit blocks under the action of hyperconcentrated flow with the hydraulic mathematical model, and belongs to the field of water conservation. According to the method, when the mathematical model is established, parameters representing intrinsic physical characteristics of the deposit blocks are introduced in, test and measured data of a to-be-calculated channel segment are combined for calculating critical starting coefficients of the channel deposit blocks, force conditions when the deposit blocks are started can be reflected more really, and the starting speeds of the deposit blocks different in size can be calculated accurately.

New use of G protein coupled acceptor kinase

Novel function of c-Jun participating in classical Wnt signal transduction path

The invention discloses a screening method of a regulator which modulates the interaction between c-Jun protein and disheveled protein. The invention also discloses a matter which can inhibit the interaction between c-Jun protein and disheveled protein, namely, a Dvl 1-M polypeptide. The invention reveals the interaction between c-Jun protein and Dvl protein in the Wnt signal transduction pathway for the first time, thus affecting the downstream Wnt signal transduction. As abnormal activation of the downstream Wnt signal transduction in the pathway is closely related to the occurrence and development of tumor, so the method provides a new target for screening drugs inhibiting the occurrence and development of tumor.

Novel function of disheveled protein and beta-catenins interactive function in classical Wnt signal transduction path

The invention discloses a screening method of a regulator which modulates the interaction between disheveled protein and beta-catenin. The invention also discloses a matter which can inhibit the interaction between disheveled protein and beta-catenin, namely, a Dvl 1-C polypeptide. The invention reveals the interaction between disheveled protein and beta-catenin in the Wnt signal transduction pathway for the first time, thus affecting the downstream Wnt signal transduction. As abnormal activation of the downstream Wnt signal transduction in the pathway is closely related to the occurrence and development of tumor, so the method provides a new target for screening drugs inhibiting the occurrence and development of tumor.

Reservoir hydro-fluctuation belt vegetation cultivation experiment device based on modular replacement and use method

The invention discloses a reservoir hydro-fluctuation belt vegetation cultivation experimental device based on modular replacement. The experimental device comprises an experimental device main body, and a water circulation system, an electric power system and a sampling and sample replacing system which are arranged in the experimental device main body. According to the experimental device, the survival conditions of different vegetation on the hydro-fluctuation belt at different water levels can be quickly and conveniently obtained by simply adjusting the water level. Through the prepared vegetation soil module, a next contrast experiment can be carried out only through temporary cleaning after one experiment is completed. And through control and comparison of multiple experimental influence factors, optimal plant variety selection is carried out on an actual site so as to achieve the optimal soil fixation effect, water eutrophication caused by the fact that the plants are flooded and ...