12-08-2021 дата публикации
Номер: US20210246126A1
Принадлежит:
The invention discloses compounds for treatment or prevention of liver diseases. The compounds are compounds represented by a formula (I) or (II), optical isomers or pharmaceutically acceptable salts of the compounds. The compounds and optical isomers or pharmaceutically acceptable salts of the compounds can be applied to preparation of drugs for treatment or prevention of liver diseases. 2. The compounds claim 1 , optical isomers or pharmaceutically acceptable salts thereof according to claim 1 , wherein claim 1 ,{'sup': 1', '2, 'sub': 1-3', '1-3', '1-3', '1-3', '1-3', '1-3, 'Ror Ris each independently selected from one or more of the group consisting of hydrogen, hydroxyl, halogen, cyano, carboxyl, Calkyl, substituted Calkyl, Calkoxy, substituted Calkoxy, Calkylthio and substituted Calkylthio, and the substituent is selected from one or more of the group consisting of deuterium, hydroxyl, amino, nitro, halogen, cyano, carboxyl and glycosyl;'}{'sup': 1', '2, 'sub': 1-3', '1-3', '1-2', '1-2, 'Ror Ris each preferably independently selected from one or more of the group consisting of hydroxyl, fluorine, chlorine, cyano, Calkyl, substituted Calkyl, Calkoxy and substituted Calkoxy, and the substituent is selected from one or more of the group consisting of deuterium, hydroxyl, amino, nitro, fluorine, chlorine, cyano and carboxyl;'}m or n is 0, 1, or 2;m or n is preferably 1 or 2.3. The compounds claim 1 , optical isomers or pharmaceutically acceptable salts thereof according to claim 1 , wherein claim 1 ,{'sup': 3', '4, 'sub': 1-3', '1-5', '1-3', '1-3, 'Ror Ris each independently selected from the group consisting of hydrogen, deuterium, hydroxyl, amino, nitro, cyano, Calkyl, substituted Calkyl, Calkoxy and substituted Calkoxy, and the substituent is selected from one or more of the group consisting of deuterium, hydroxyl, amino, nitro, cyano, carboxyl and glycosyl;'}{'sup': 3', '4, 'sub': 1-3', '1-3, 'Ror Ris preferably each independently selected from the group ...
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