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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 36. Отображено 36.
23-06-2023 дата публикации

Polypeptide function prediction method and device

Номер: CN116312750A
Автор: LAI REN, RONG MINGQIANG, GU ZHIXIN, LI ZONGXU
Принадлежит:

The invention discloses a polypeptide function prediction method and device. The method comprises the steps of data set construction and data preprocessing; establishing a multi-label prediction model, wherein the multi-label prediction model is composed of a feature embedding module, a multi-scale convolutional neural network CNN module, a BiGRU module for processing a context-related sequence and a classification module; training the constructed network model by using the obtained data set, and improving model feature extraction and parameter prediction performance by using an optimization algorithm; and the performance of the multi-label prediction model is evaluated through five indexes of calculation precision, coverage rate, accuracy, absolute true value and absolute false value. According to the method, association between the tags is effectively utilized, the accuracy of polypeptide function prediction is improved, the method is high in operability and practicability, can be applied ...

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Номер записи: 1
30-06-2023 дата публикации

Method and system for removing propeptide in amino acid sequence assembled by generating signal, and storage medium

Номер: CN116364187A
Автор: LAI REN, RONG MINGQIANG, GU ZHIXIN, HUANG SEN, LI ZONGXU
Принадлежит:

The invention discloses a method and a system for removing propeptide in an amino acid sequence assembled by a biological information process and a storage medium, and relates to the field of biological information, in particular to data mining of transcriptome sequencing, acquisition of polypeptide sequence information generated by the biological information process and application of the polypeptide sequence information to the biological information process. Performing segmentation comparison on the polypeptide sequence information to obtain a protein file meeting a preset requirement; performing data cleaning on the obtained protein file; screening a sequence with the highest homology according to the obtained protein file, and integrating the sequence with polypeptide sequence information; determining a reserved part in the polypeptide sequence information according to the position of the target protein in the protein file; and storing the information after data cleaning. The method ...

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Номер записи: 2
23-06-2023 дата публикации

Application of polypeptide RK12 as active ingredient

Номер: CN116270966A
Автор: LONG CHENGBO, LAI REN, RONG MINGQIANG, GU ZHIXIN, ZHANG MINGYU
Принадлежит:

The invention belongs to the field of biological medicine, and discloses application of polypeptide RK12 as an active ingredient, bacterial cell death is caused by utilizing interaction between the polypeptide RK12 and a bacterial cell wall membrane, inducing leakage of contents in cells and destroying completeness of bacterial thalli, meanwhile, healing of diabetic ulcer wounds can be promoted, and the polypeptide RK12 has the advantages of being easy to synthesize, free of toxic and side effects and the like. Therefore, the compound has a good clinical application prospect when being used for treating ulcers or wounds of diabetics caused by combined infection.

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Номер записи: 3
14-07-2023 дата публикации

Method for analyzing related substances of polypeptide PD-DP-005

Номер: CN116429950A
Автор: ZHAN PEI, RONG MINGQIANG, GU ZHIXIN
Принадлежит:

The invention relates to the technical field of polypeptide drug analysis and detection, in particular to a method for analyzing related substances of polypeptide PD-DP-005. According to the method, a chromatographic column with octadecylsilane chemically bonded silica as a filler is used as a stationary phase, an ammonium sulfate buffer solution is used as a mobile phase, the ammonium sulfate buffer solution inhibits ionization of silanol groups on the chromatographic column, unnecessary interaction between the stationary phase and a protonated solute of a polypeptide PD-DP-005 sample is reduced, the phenomenon of chromatographic peak tailing is reduced, and the accuracy of detection of the polypeptide PD-DP-005 sample is improved. Under specific chromatographic conditions, the selectivity and retention capacity of the polypeptide PD-DP-005 in a stationary phase are improved, the separation effect is improved, more impurities can be detected, the chromatographic peak of the main component ...

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Номер записи: 4
04-07-2023 дата публикации

Method and system for batch acquisition of open shared sequencing data, and storage medium

Номер: CN116386735A
Автор: LAI REN, RONG MINGQIANG, GU ZHIXIN, LI ZONGXU
Принадлежит:

The invention discloses a batch acquisition method and system for open shared sequencing data and a storage medium. The batch acquisition method comprises the following steps: firstly, acquiring sequencing data JSON; then obtaining a sequencing data link address and a classification number according to the sequencing data JSON; secondly, obtaining a sequencing data downloading address according to the sequencing data link address; and finally, downloading the sequencing original data set in batches according to the sequencing data downloading address. According to the method, on the basis of a Python script process for automatically obtaining Web page data and integrating classified information in batches, the purposes of labeling the classified information and obtaining original experimental data in one step are achieved. And the limitation of data barriers in the prior art is broken.

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Номер записи: 5
11-02-2015 дата публикации

Qualitative and quantitative detection method of bronchitis tablets

Номер: CN104345116A
Автор: OU JINXIU, GU ZHIXIN, ZHANG NIYU, XIN XIU, XI RUIYUN, YUAN LI, ZHU LI, YAN DONGLAN
Принадлежит:

The present invention discloses a qualitative and quantitative detection method of bronchitis tablets. The method comprises: (1) adopting a thin layer chromatography method to identify Scutellaria baicalensis Georgi and licorice root; and (2) adopting a high performance liquid chromatography method to determine ephedrine hydrochloride and the bergenin content in Japanese Ardisia Herb, wherein the Japanese Ardisia Herb content in each bronchitis tablet is not less than 2.1 mg (calculated as the bergenin, and the ephedrine hydrochloride (C10H15NO.HCl) content in each bronchitis tablet is 70.0-110.0% of the labeled amount. According to the present invention, with the method, the product quality controllability can be increased, and the shortcomings in the prior art can be overcome so as to well ensure the efficacy and provide good service for the majority of patients.

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Номер записи: 6
23-06-2023 дата публикации

Polypeptide LGTX-F2 mutant and application thereof

Номер: CN116284308A
Автор: LAI REN, RONG MINGQIANG, GU ZHIXIN, HUANG BIAO
Принадлежит:

The invention discloses a polypeptide LGTX-F2 mutant and application thereof.According to the mutant, single amino acid at the second site, the seventh site, the tenth site and the twentieth site of natural LGTX-F2 amino acid replaces amino acid with positive charges, at least one amino acid of the 45-65 site amino acid is deleted, the stability of the obtained polypeptide LGTX-F2 mutant is improved under the conditions of different pH values, temperatures, metal ions, solvents and enzymes, and the polypeptide LGTX-F2 mutant can be used for preparing the polypeptide LGTX-F2 mutant. The defect that the stability of the polypeptide in vivo is poor is overcome, and the polypeptide LGTX-F2 has great significance in development of novel hemostatic drugs.

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Номер записи: 7
11-07-2023 дата публикации

Polypeptide TG-28 and application thereof

Номер: CN116410261A
Автор: GU ZHIXIN, HUANG BIAO
Принадлежит:

The invention provides a polypeptide TG-28 and an application thereof. The polypeptide TG-28 disclosed by the invention can be specifically combined with SARS-CoV-2 S protein, can effectively block the combination of the S protein and ACE2 protein, does not act with ACE2, and specifically prevents the virus from infecting human cells, so that the polypeptide TG-28 can be used for preventing and/or treating new coronavirus infection. The binding constant KD value of the polypeptide TG-28 and the SARS-CoV-2 S protein is 2.69 * 10 <-8 > M, binding is slow, dissociation is basically avoided after binding, and pseudovirus neutralization experiments prove that the polypeptide TG-28 prevents viruses from entering cells in a concentration-dependent mode. The polypeptide TG-28 disclosed by the invention lays a foundation for developing products for preventing and/or treating new coronavirus infection.

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Номер записи: 8
12-02-2014 дата публикации

Inhalation preparation with polysaccharide nucleic acid of bacillus calmette Guerin as active component

Номер: CN103565780A
Автор: LIU FANGJIE, YAN DONGLAN, GU ZHIXIN
Принадлежит:

The invention provides an inhalation preparation with the polysaccharide nucleic acid of bacillus calmette Guerin as an active component. The inhalation preparation is a pharmaceutical composition prepared from the polysaccharide nucleic acid of bacillus calmette Guerin and pharmaceutically acceptable adjuvant. The invention further provides a preparation method for the inhalation preparation. The inhalation preparation is mainly used for prevention and treatment of respiratory tract infection and asthma.

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Номер записи: 9
11-02-2015 дата публикации

Qualitative quantitative determination method for liver-heat-clearing tablet

Номер: CN104345108A
Автор: XI RUIYUN, GU ZHIXIN, ZHANG NIYU, OU JINXIU, XIN XIU, LIU SHUFENG, YUAN LI, ZHU LI
Принадлежит:

The invention discloses a qualitative quantitative determination method for a liver-heat-clearing tablet, and a conventional qualitative identification method for herba artemisiae scopariae in the liver-heat-clearing tablet is improved. The following steps are increased: (1) employing a microscopic identification process to identify radix isatidis in the liver-heat-clearing tablet; (2) employing thin-layer chromatography to identify radix isatidis in the liver-heat-clearing tablet by taking indirubin as a reference; and (3) employing high performance liquid chromatography to determine the content of chlorogenic acid in herba artemisiae scopariae and the content of glycyrrhizic acid in glycyrrhiza. Compared with the prior art, in the method, a qualitative discriminating method is added and also the content determination method for the effective compositions is added. The method is high in precision, good in reproducibility, high in recovery rate and accurate in determination result, and ...

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Номер записи: 10
17-12-2014 дата публикации

Callicarpa nudiflora medicine, intermediate and fingerprint detection method and standard fingerprint of preparation

Номер: CN104215698A
Автор: LU FENGLAI, ZHANG NIYU, GU ZHIXIN, XIN XIU, LI DIANPENG, YUAN LI, HUANG SHENG, YAN DONGLAN, ZHU LI, YAN XIAOJIE, CHEN SHISHENG
Принадлежит:

The invention discloses a callicarpa nudiflora medicine, an intermediate and a fingerprint detection method of a preparation. The method comprises the following steps: (a) preparation of a reference solution; (b) preparation of a test solution; (c) chromatographic condition; (d) formulation of a standard fingerprint of isoacteoside as a reference peak; and (e) quality control of the fingerprint. According to the above method, a pretreatment method of each tested object is simple, characteristic constituents are retained completely, stability is good, precision is high, and there is certain specificity. The separation effect of each characteristic peak in the fingerprint is good. The callicarpa nudiflora medicine, the intermediate and the fingerprint of the preparation have good correlation. The method can be used for identifying quality of the callicarpa nudiflora medicine and increasing production process controllability of the callicarpa nudiflora preparation, and is helpful for guaranteeing ...

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Номер записи: 11
29-10-2014 дата публикации

Preparation method for kidney-tonifying traditional Chinese medicine oral liquid

Номер: CN104116891A
Автор: ZHU LI, GU ZHIXIN, YUAN LI, YAN DONGLAN, HUANG SHENG, OU JINXIU, LIU SHUFENG, XI RUIYUN
Принадлежит:

A disclosed preparation method for a kidney-tonifying traditional Chinese medicine oral liquid comprises: performing water extraction on cow's penis, radix astragali and other raw medicinal materials, adding a flocculation clarifying agent into the extraction liquid, standing, filtering for separation, filtering the obtained medicinal solution with a ceramic membrane, mixing the filtrate with alcohol extraction liquids of panax ginseng and cornu cervi pantotrichum, adding proper auxiliary materials to prepare the oral liquid. On the one hand, the method reduces loss of effective compositions and decomposition change of a part of compositions, and improves the utilization rate of medicinal materials; and on the other hand, through combination of a flocculation clarifying technology and a ceramic membrane filtering technology for finely preparing the medicinal solution, macromolecule substances such as tannin and the like are removed, and effective compositions such as polysaccharides and ...

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Номер записи: 12
30-09-2015 дата публикации

Ocean fish oligopeptide powder solid drink and preparation method thereof

Номер: CN104939258A
Автор: OU JINXIU, GU ZHIXIN, YUAN LI, ZHU LI, REN JIEFANG, YAN DONGLAN, LIU SHUFENG, SUN MENGJIN
Принадлежит:

The invention discloses an ocean fish oligopeptide powder solid drink and a preparation method thereof. The ocean fish oligopeptide powder solid drink is prepared from the following raw materials in percentage by weight, 40-60% of ocean fish oligopeptide powder, 20-35% of glucose, 0.1-0.2% of citric acid and 10-25% of maltodextrin through the procedures of crushing, mixing, granulating, finishing, drying and the like, and has the advantages of reasonable formula and good taste, is nutritional and healthy, easy to carry, and convenient and sanitary.

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Номер записи: 13
25-07-2023 дата публикации

Method and system for automatically screening active polypeptide based on cysteine motif, and storage medium

Номер: CN116486915A
Автор: LAI REN, RONG MINGQIANG, GU ZHIXIN, HUANG SEN
Принадлежит:

The invention discloses a method and a system for automatically screening active polypeptides based on a cysteine motif, and a storage medium. The method comprises the following steps: firstly, acquiring and inputting a to-be-analyzed sequence and a sub-sequence thereof; then calculating a cysteine motif of the input sequence, and obtaining a sub-sequence with the same cysteine motif and a corresponding active peptide sequence; and calculating the difference value of the number of amino acids between the cysteines, reserving a subsequence according to the difference value of the number of the amino acids, finally calculating the similarity between the subsequence and a sequence corresponding to the active peptide in the database, and selecting the active peptide with the similarity meeting a preset condition to obtain the active peptide sequence of the cysteine toxic polypeptide. According to the method, the problem of low manual recognition efficiency is solved, the active peptide sequences ...

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Номер записи: 14
03-03-2010 дата публикации

Lansoprazole enteric-coated tablet and preparation method thereof

Номер: CN0101658509A
Автор: GU ZHIXIN, WU JIANMIN, YANG JUN, ZHU MIN, ZHANG JING, HE LIAN, XIAO LIANHONG, ZHIXIN GU, JIANMIN WU, MIN ZHU, JING ZHANG, LIAN HE, LIANHONG XIAO
Принадлежит:

The invention discloses a lansoprazole enteric-coated tablet and a preparation method thereof, wherein a tablet core of the lansoprazole enteric-coated tablet contains active ingredients selected fromlansoprazole and medical excipient, and a middle isolation layer and an enteric coating protection layer are wrapped outside the tablet core. In the invention, the medicinal preparation is prepared by adopting the following steps: firstly mixing main materials and surfactant, then adding other auxiliary granules, taking calcium carbonate as a sterilizing agent and utilizing hydroxypropyl methylcellulose and talcum powder. The lansoprazole enteric-coated tablet does not contain trace organic solvents and has stable property, and neither the isolation layer nor the enteric coating protection layer contains obstacles, such as the surfactant, and the like, thereby being more favorable to body health and safety. The preparation method does not use organic solvents, and has simple operation, short ...

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Номер записи: 15
14-07-2023 дата публикации

Application of polypeptide PD-DP-005 in preparation of medicine for treating lung diseases and medicine of polypeptide PD-DP-005

Номер: CN116421704A
Автор: LAI REN, RONG MINGQIANG, GU ZHIXIN, HUANG BIAO
Принадлежит:

The invention provides an application of a polypeptide PD-DP-005 in preparation of a medicine for treating lung diseases and the medicine of the polypeptide PD-DP-005. A bleomycin-induced mouse pulmonary fibrosis model experiment is carried out, and lung injury, lung inflammation infiltration and fibrosis lesion of the bleomycin-induced mouse pulmonary fibrosis model can be effectively inhibited in a tracheal spray administration mode; after the mouse is dissected, the influence symptom of the medicine on each organ of the mouse is not found. A COPD animal model experiment is carried out, and lung injury and lung inflammation infiltration can be improved in a tracheal spray administration mode; after the mouse is dissected, the influence symptom of the medicine on each organ of the mouse is not found. Lipopolysaccharide-induced mouse acute lung injury animal model experiments are carried out, and lung injury and lung inflammation infiltration can be remarkably improved in a caudal vein ...

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Номер записи: 16
10-02-2016 дата публикации

Effluent treatment plant slaughters

Номер: CN0205024039U
Автор: XIA YUFENG, JIA DEZHI, WEI JUNLING, GU ZHIXIN
Принадлежит:

The utility model relates to an environmental protection field especially relates to effluent treatment plant slaughters. Contain the catch -basin that catchments, the catch -basin that catchments contains butchers waste water and gets into the pipeline, contains the solid -liquid separation machine on the catch -basin that catchments, installs mixing pump on the catch -basin that catchments, and the catch -basin avris that catchments contains oil removal check slag bath, stretching out pipe connection equalizing basin and accident pond in the oil removal check slag bath respectively, installing the elevator pump on the accident pond, the elevator pump passes through the pipe connection rotary drum filter, and the rotary drum filter passes through pipe connection anaerobism device, and the equalizing basin is still connected to the rotary drum filter, and the equalizing basin is also connected to the anaerobism device, and the anaerobism device still passes through concentrated pond of ...

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Номер записи: 17
09-04-2014 дата публикации

Extracting and collecting device and application thereof

Номер: CN103706142A
Автор: HUANG SHENG, GU ZHIXIN, CHEN JIANJUN, YUAN LI, ZHU LI, ZHOU FANG, CUI YANBIN, DAI XIANGGUO
Принадлежит:

The invention discloses an extracting and collecting device, and specifically relates to an extracting and collecting device for volatile components. The extracting and collecting device comprises an extracting tank (1), an extracting tank outlet (2), a safety valve (3), a pipeline (4), a liquid storage tank (6), an interlayer (11), an exhaust outlet (7), a condensate water inlet (8) and a condensate water outlet (5) and a liquid draining device (8). The extracting and collecting device has the beneficial effects that the structure is simple; operations are convenient; the liquid storage tank has the collecting and condensing functions; use amount of the condensate water is significantly reduced; and collection efficiency of the volatile components can be increased.

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Номер записи: 18
19-02-2014 дата публикации

Bacillus calmette-guerin polysaccharides nucleic acid buccal tablet

Номер: CN103585121A
Автор: LIU FANGJIE, GU ZHIXIN, LIU NIAN, YAN DONGLAN, XIN XIU, ZHANG NIYU
Принадлежит:

A provided bacillus calmette-guerin polysaccharides nucleic acid buccal tablet is a pharmaceutical composition prepared from bacillus calmette-guerin polysaccharides nucleic acid and pharmaceutically acceptable auxiliary agents. The invention also provides a preparation method of the buccal tablet. The buccal tablet is mainly used to prevent and treat respiratory tract infection and asthma.

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Номер записи: 19
24-12-2014 дата публикации

Method for detoxification micropropagation of callicarpa nudiflora

Номер: CN104221852A
Автор: ZHANG YINGBO, YU FULAI, LI WEI, PANG YUXIN, GU ZHIXIN, HUANG SHENG, XU XIANGPING, WANG DAN, GUAN LINGLIANG, YUAN LI
Принадлежит:

The invention provides a method for detoxification micropropagation of callicarpa nudiflora, and relates to solve the problems of long propagation period of the callicarpa nudiflora, low propagation efficiency and high cost by using a method of plant detoxification micropropagation and tissue culture. The method comprises the steps of (1) detoxification of explants; (2) culture of aseptic seedlings; (3) culture of micro branches: transplanting proliferated aseptic seedlings into a seedling-strengthening culture medium to culture; (4) propagation culture: cutting the strengthened micro branches into segments with one apical bud or 1-2 axillary buds for culture; (5) rooting culture: transplanting the micro branches to a rooting culture medium when the growth length of the micro branches reaches 2.0-3.0 cm; (6) hardening culture: hardening the rooting cultured callicarpa nudiflora seedlings in a sunshelter for 7-10 d; and (7) transplanting callicarpa nudiflora seedlings after hardening of ...

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Номер записи: 20
16-07-2014 дата публикации

Determination method for content of total phenols in callicarpa nudiflora

Номер: CN103926212A
Автор: LI DIANPENG, YUAN LI, HUANG SHENG, YAN XIAOJIE, LU FENGLAI, PAN ZHENGHONG, GU ZHIXIN, XU XIANGPING, CHEN ZHENGUI
Принадлежит:

The invention relates to a determination method for the content of total phenols in callicarpa nudiflora. The determination method employs a spectrophotometric process to determine the content of total phenols in callicarpa nudiflora, and is beneficial for quantitative control on the callicarpa nudiflora medicinal material, callicarpa nudiflora extracts and callicarpa nudiflora preparations.

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Номер записи: 21
11-02-2015 дата публикации

Qualitative and quantitative detection method of anti-hyperostosis tablets

Номер: CN104345115A
Автор: ZHANG NIYU, GU ZHIXIN, XIN XIU, OU JINXIU, XI RUIYUN, LIU SHUFENG, YUAN LI, ZHU LI
Принадлежит:

The present invention discloses a qualitative and quantitative detection method of anti-hyperostosis tablets, wherein the following schemes are added: (1) a thin-layer chromatography method is adopted and naringin is adopted as the control to identify whether the anti-hyperostosis tablet contains Rhizoma Drynariae; a Caulis Spatholobi control herb is adopted as the control to identify whether the anti-hyperostosis tablet contains Caulis Spatholobi; and icariin is adopted as the control to identify whether the anti-hyperostosis tablet contains epimedium; and (2) a high performance liquid chromatography method is adopted to determine the icariin content in the anti-hyperostosis tablet. Compared with the method in the prior art, the qualitative and quantitative detection method of the present invention has the following advantages that: the qualitative identification method is added, the effectively component content determination method is added, the revised quality standard is provided, ...

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Номер записи: 22
07-05-2014 дата публикации

Traditional Chinese medicine health-care absorbing article

Номер: CN103768647A
Автор: YUAN LI, GU ZHIXIN, LIU SHUFENG, YAN DONGLAN, TANG TING, ZHOU FANG, ZHU LI, XI RUIYUN
Принадлежит:

The invention provides a traditional Chinese medicine health-care absorbing article which comprises a liquid penetrable surface layer (1), a liquid unpenetrable surface layer (5), an absorption core (4) between the former two layers, wherein the absorption core comprises a medicine filling layer (2) close to the liquid penetrable surface layer and an absorbing layer (3) formed by wood pulp and/or fluff slurry and/or ultra-absorption polymer, and further comprises a fixing gum (6) and a piece of gum protecting stripping paper (7); the traditional Chinese medicine in the medicine filling layer (2) takes callicarpa nudiflora as main raw material, and also comprises radix sophorae flavescentis and blumea balsamifera. The absorbing article provided has the functions of resisting and arresting bacterium, ridding dampness, alleviating pain, and killing parasites to relieve itching.

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Номер записи: 23
29-10-2014 дата публикации

Preparation method for kidney-tonifying traditional Chinese medicine preparation

Номер: CN104116892A
Автор: ZHU LI, YUAN LI, GU ZHIXIN, HUANG SHENG, YAN DONGLAN, LU JIE, LIU SHUFENG, XI RUIYUN
Принадлежит:

A disclosed preparation method for a kidney-tonifying traditional Chinese medicine preparation comprises: performing superfine grinding on expensive fine medicinal materials such as panax ginseng and cornu cervi pantotrichum, performing water extraction on residual medicinal materials, adding a flocculation clarifying agent into the extraction liquid, standing and filtering for separation, concentrating the obtained medicinal solution, uniformly mixing with the above superfine powder obtained through superfine grinding, and adding proper auxiliary materials for preparing the preparation. On the one hand, the method reduces loss of effective compositions and decomposition change of a part of compositions, and improves the utilization rate of the medicinal materials; and on the other hand, by employing a flocculation clarifying technology for finely preparing the medicinal solution, macromolecule substances such as tannin and the like are removed, and effective compositions such as polysaccharides ...

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Номер записи: 24
09-06-2023 дата публикации

Method for purifying polypeptide toxin in batches and composite double-layer chromatographic column

Номер: CN116236819A
Автор: HUANG BIAO, RONG MINGQIANG, GU ZHIXIN
Принадлежит:

The invention provides a method for purifying polypeptide toxins in batches and a composite double-layer chromatographic column, and belongs to the technical field of polypeptide purification. According to the method, fermentation bacteria liquid of prokaryotic expression polypeptide toxin is pretreated and then subjected to nickel column affinity chromatography, protease digestion and compound type double-layer chromatographic column purification, a gel filtering filler and a reverse high performance liquid chromatography filler are laid in a column body of the compound type double-layer chromatographic column from top to bottom, the column volume is 12-30 mL, and the pH value of the column is 7-8. The mass ratio of the gel filtration filler to the reverse high performance liquid chromatography filler is 1: (1-2), the compound double-layer column is used for one-step purification to quickly desalt and remove impure protein, batch purification of different 1L of prokaryotic expression polypeptide ...

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Номер записи: 25
23-06-2010 дата публикации

Compound Chinese medicinal preparation for treating fatty liver, alcoholic hepatitis and complications

Номер: CN0101745077A
Автор: ZHIXIN GU, LIAN HE, YANG JUN, JING ZHANG, GU ZHIXIN, HE LIAN, ZHANG JING
Принадлежит:

The invention discloses a compound Chinese medicinal preparation, e.i. Ganfule. The compound Chinese medicinal preparation comprises pilose asiabell root, largehead atractylodes rhizome, ground beeltle, barbed skullcap herb, coix seed, oyster, nutgrass galingale rhizome, turtle shell, raidx astragali, rhubarb, dahurian patrinia herb, turmeric root-tuber, virgate wormwood herb, Chinese eaglewood, Yunnan manyleaf paris rhizome, tangerine peel, poria, sappan wood, armand clematis stem, peach seed and bupleurum, has effects of strengthening the spleen and regulating qi, eliminating stasis and softening hardness and clearing away heat and toxic material, is suitable for primary liver cancer with the main symptoms of liver stasis and spleen deficiency, and has novel medicinal applications of treating fatty liver, alcoholic hepatitis, hepatocirrhosis, liver fibrosis and hepatic ascites which are caused by long-term excessive drinking or intemperance.

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Номер записи: 26
17-03-2010 дата публикации

Method for preparing vehicle fuel similar to natural gas by impurity removal and purification of marsh gas in composite separation mode

Номер: CN0101671585A
Автор: TAN WENYING, LIANG SUYU, WANG SHUYANG, XU KAIHONG, ZENG QILIANG, LI ERPING, SHEN YONGLIANG, CHANG TONGLI, PAN QIMING, SUN GUOYONG, GU ZHIXIN, SUN XUE, LIU XIANGDONG, ZHAO JUN, CAO YOUWEI, WENYING TAN, SUYU LIANG, SHUYANG WANG, KAIHONG XU, QILIANG ZENG, ERPING LI, YONGLIANG SHEN, TONGLI CHANG, QIMING PAN, GUOYONG SUN, ZHIXIN GU, XUE SUN, XIANGDONG LIU, YOUWEI CAO
Принадлежит:

The invention relates to a method for purifying and refining march gas into civilian gas fuel and vehicle fuel similar to natural gas in a composite step-by-step separation mode. At present, the marshgas in China is not deeply dehydrated, desulfurized and decarbonized generally and is only preliminarily desulfurized and dehydrated. Because the common marsh gas contains sulfur, CO2 and other impurities, and has a low volume calorific value, high content of harmful gas impurities and poor quality, the marsh gas cannot reach the standard of compressed natural gas for vehicles. The method generally adopts the nano and micro materials and combination optimized configuration technology-based novel high-efficiency desulfurization technology and a multi-level film composite step-by-step separation method with permeating gas refluxing and residual gas utilizing functions to highly efficiently remove impurities, purify and deeply process the marsh gas so as to make the conventional marsh gas become ...

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Номер записи: 27
11-02-2015 дата публикации

Qualitative and quantitative detection method of compound Japanese Ardisia Herb tablets

Номер: CN104345117A
Автор: XIN XIU, GU ZHIXIN, ZHANG NIYU, OU JINXIU, XI RUIYUN, YUAN LI, ZHU LI, YAN DONGLAN
Принадлежит:

The present invention discloses a qualitative and quantitative detection method of compound Japanese Ardisia Herb tablets, wherein microscopic identification of Japanese Ardisia Herb in the compound Japanese Ardisia Herb tablets is improved, thin-layer chromatography identification of Japanese Ardisia Herb, Dendranthema indicum and licorice root in the compound Japanese Ardisia Herb tablets is added, and a determination method of the bergenin content in the compound Japanese Ardisia Herb tablets is established. According to the qualitative and quantitative detection method, the identification is provided, wherein the microscopic identification method is adopted to identify the Japanese Ardisia Herb, and the thin-layer chromatography method is adopted to identify the Japanese Ardisia Herb, the Dendranthema indicum and the licorice root; the content determination is provided, wherein the high performance liquid chromatography method is adopted to determine the bergenin content in the Japanese ...

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Номер записи: 28
30-09-2015 дата публикации

Ocean fish oligopeptide tablet candy and preparation method thereof

Номер: CN104938740A
Автор: GU ZHIXIN, REN JIEFANG, OU JINXIU, HUANG SHENG, ZHU LI, YUAN LI, CHEN SHISHENG, SUN MENGJIN
Принадлежит:

The invention discloses an ocean fish oligopeptide tablet candy and a preparation method thereof. The ocean fish oligopeptide tablet candy is characterized in that raw materials such as 15 to 30 percent of ocean fish oligopeptide powder, 14.99 to 30 percent of glucose, 0.01 to 0.05 percent of aspartame and 40 to 60 percent of maltodextrin are crushed, mixed, granulated, shaped, dried and tabletted to form the tablet candy. The tablet candy has the advantages of being reasonable in formula, good in taste, nutritional, healthy, easy to carry, convenient and sanitary.

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Номер записи: 29
20-08-2014 дата публикации

Traditional Chinese medicine composition and preparation method thereof

Номер: CN103989960A
Автор: CHEN ZHENGUI, LU JIE, PENG QIZHOU, GU ZHIXIN, XU XIANGPING, ZHU LI, XIE AN, YUAN LI, XI RUIYUN
Принадлежит:

A provided traditional Chinese medicine composition is prepared from bulk drugs such as salvia miltiorrhiza, cape jasmine, radix paeoniae rubra, cortex moutan and the like. The traditional Chinese medicine composition is used to treat blood-stasis obstruction and kidney deficiency syndromes at a meridian recovery period of apoplexy, and the syndromes show hemiplegia, deviation of mouth and tongue, stiff tongue and retardation in speech, hemianesthesia, dizziness, soreness and weakness of waist and knees, and the like; the traditional Chinese medicine composition is also used to treat a patient possessing the above symptoms at a cerebral infarction recovery period. The invention also discloses a preparation method of the traditional Chinese medicine composition.

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Номер записи: 30
24-02-2010 дата публикации

Technology of large-scale refining production of glycyrrhetate

Номер: CN0101654471A
Автор: YANG JUN, ZHIXIN GU, JING ZHANG, LIAN HE, LIANHONG XIAO, GU ZHIXIN, ZHANG JING, HE LIAN, XIAO LIANHONG
Принадлежит:

The invention relates to a technology of large-scale refining production of glycyrrhetate, comprising the following steps: grinding, extracting by water, supercritically extracting CO2, separating, acidizing, crystallizing, decoloring and recrystallizing. The glycyrrhizic acid ion of glycyrrhetate prepared by the technology contains trivalent ions, divalent ions and monatomic ions. The glycyrrhetate comprises metal ions, such as ammonium, potassium, sodium, magnesium, zinc, bismuth and the like; the purity of the glycyrrhetate exceeds 99%. The invention has the advantages of advanced technology, simple operation, ideal refining and high product purity and is convenient for producing on large scale, and raw material conforms to medical application.

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Номер записи: 31
27-04-2011 дата публикации

Manufacture process of piperazine ferulate

Номер: CN0101555235B
Автор: WU JIANMIN, LI DUOJIAO, GU ZHIXIN, TANG JIEFENG, JIANMIN WU, DUOJIAO LI, ZHIXIN GU, JIEFENG TANG
Принадлежит:

The invention relates to a manufacture process of piperazine ferulate; wherein, ethanol is used as a solvent; ferulic acid and piperazine anhydrous are dissolved in ethanol and undergo secondary filter; under proper reaction conditions, the both react in a crystallizing tank; after the reaction is over, cooling devitrification, centrifugation, washing, vacuum drying are carried out, thus obtainingpiperazine ferulate. The manufacture process of the invention overcomes the defect that product yield of piperazine ferulate obtained by using the ferulic acid and the piperazine hexahydrate only stands at 70%. The invention features simple process, easy operation, high purity, high yield and low cost of the obtained product and easy application to industrialized mass production.

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Номер записи: 32
14-10-2009 дата публикации

Manufacture process of piperazine ferulate

Номер: CN0101555235A
Автор: WU JIANMIN, LI DUOJIAO, GU ZHIXIN, TANG JIEFENG, JIANMIN WU, DUOJIAO LI, ZHIXIN GU, JIEFENG TANG
Принадлежит:

The invention relates to a manufacture process of piperazine ferulate; wherein, ethanol is used as a solvent; ferulic acid and piperazine anhydrous are dissolved in ethanol and undergo secondary filter; under proper reaction conditions, the both react in a crystallizing tank; after the reaction is over, cooling devitrification, centrifugation, washing, vacuum drying are carried out, thus obtaining piperazine ferulate. The manufacture process of the invention overcomes the defect that product yield of piperazine ferulate obtained by using the ferulic acid and the piperazine hexahydrate only stands at 70%. The invention features simple process, easy operation, high purity, high yield and low cost of the obtained product and easy application to industrialized mass production.

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Номер записи: 33
05-02-2014 дата публикации

Thin-layer identification chromatography method of stomach-strengthening ulcer-curing preparation

Номер: CN103558330A
Автор: XIN XIU, GU ZHIXIN, ZHANG NIYU, YUAN LI, REN JIEFANG, ZHU LI, OU JINXIU, LIU SHUFENG, XIONG HAIXIA
Принадлежит:

The invention discloses a thin-layer identification chromatography method of a stomach-strengthening ulcer-curing preparation, and changes the thin-layer identification method of radix bupleuri, corydalis tuber and natural indigo in a stomach-strengthening ulcer-curing tablet, and thin-layer identification of licorice is added. Five thin-layer identification items in the current ''Chinese pharmacopoeia'' need respective test sample processing and respective developing-coloration-viewing for quality control, and are complicated and cumbersome. According to the thin-layer identification chromatography method of the invention, six thin-layer identification items share a test sample solution below a [identification] (2) item in the ''Chinese pharmacopoeia'', and are performed by four developing-coloration-viewing processes, manpower, material resources and time are saved, and the thin-layer identification of the licorice is added. The improved thin-layer identification chromatography method ...

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Номер записи: 34
12-02-2014 дата публикации

Pharmaceutical composition and application of same in preparation of drug used for treating tuberculosis

Номер: CN103566053A
Автор: GU ZHIXIN, YUAN LI, HUANG SHENG, ZHOU FANG
Принадлежит:

The invention relates to a pharmaceutical composition and application of the same in preparation of a drug used for treating tuberculosis. The composition provided by the invention is obtained by compounding a pharmaceutical composition with BCG-PSN as an active component and a traditional Chinese medicine together, wherein the traditional Chinese medicine is mainly from callicarpa nudiflora.

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Номер записи: 35
14-04-2010 дата публикации

Traditional Chinese medicine compound preparation for treating viral hepatitis and complication

Номер: CN0101693094A
Автор: YANG JUN, ZHIXIN GU, LIAN HE, JING ZHANG, GU ZHIXIN, HE LIAN, ZHANG JING
Принадлежит:

The invention discloses a compound traditional Chinese medicine preparation-Ganfule which contains traditional Chinese medicines of radix codonopsitis, Rhizoma Atractylodis Macrocephalae, woodlouse, Barbed Skullcap Herb, Coix lachrymajobi, oyster, Cyperi Rhizoma, testa trionidis, radix astragali, rhubarb, Herba Patriniae, radix curcumae, Herba Artemisiae Capillaris, tambac, Rhizoma Paridis, dried tangerine peel, tuckahoe, sapanwood, armand clematis, peach kernel and radix bupleuri, has the efficiencies of invigorating the spleen, regulating the flow of vital energy, removing blood stasis, softening hardness and clearing away heat and toxic material and is suitable for primary carcinoma of liver taking stagnation of liver-QI with deficiency of the spleen as the main symptom. The preparation is used for treating various viral hepatitis, such as acute hepatitis, chronic hepatitis and severe hepatitis which are caused by hepatitis viruses, cholestatic hepatitis, hepatitis hepatocirrhosis and ...

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Номер записи: 36