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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 5. Отображено 5.
17-08-2011 дата публикации

Fermentation technology for preparing high-molecular weight sodium hyaluronate

Номер: CN0102154401A
Автор: ZHANG ZHENWU, BA FENGLIANG, ZHANG HAIBIN, ZHU LIANMING, JIANG GUIXIN, ZHOU TAIMING, ZHENWU ZHANG, FENGLIANG BA, HAIBIN ZHANG, LIANMING ZHU, GUIXIN JIANG, TAIMING ZHOU
Принадлежит:

The invention provides fermentation technology for preparing high-molecular weight hyaloplasm sodium hyaluronate, wherein the high-molecular weight hyaloplasm sodium hyaluronate consists of starch, cane sugar, beef extract, yeast powder, dialkyl potassium sulfate, sodium hydroxide, water and foam oil; and the high-molecular weight hyaloplasm sodium hyaluronate prepared by the fermentation technology comprises the following steps: adding raw materials which are prepared in proportion into 15-25ml of foam oil and pouring the mixture into a tank, cultivating in a dissolving way by adding water with proper amount, pouring into a fermentation tank after cultivating, heating up feed liquid in the tank, adjusting an exhaust steam valve to lead the pressure of the tank to be kept at 0.11+/-0.01MPa and lead the temperature to be kept at 121+0.5 DEG C; keeping the temperature and the pressure for 25-30 minutes; cooling the feed liquid to be at 37 DEG C by turning on interlayer cooling water and keeping ...

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Номер записи: 1
29-12-2010 дата публикации

Method for producing pharmaceutical-grade glycosaminoglycan by biological fermentation process

Номер: CN0101928737A
Автор: ZHANG ZHENWU, ZHANG HAIBIN, ZHU LIANMING, JIANG GUIXIN, ZHENWU ZHANG, HAIBIN ZHANG, LIANMING ZHU, GUIXIN JIANG
Принадлежит:

The invention provides a method for producing pharmaceutical-grade glycosaminoglycan by a biological fermentation process. The method comprises the following steps of: sequentially mixing 0.5 mass percent of glucose, 0.5 mass percent of yeast powder, 0.02 mass percent of potassium acid phosphate, 0.05 mass percent of magnesium sulfate and 97.43 mass percent of water in a shake flask to prepare a strain; placing the mixture in a shaking table, controlling the temperature at 37+/-0.5 DEG C and culturing the mixture at a constant temperature; inoculating the strain into a seeding tank by means of pressure difference under the protection of flames; inoculating the strain into a fermentation tank for fermentation after the inoculation and fully turning the strain; and performing emulsification, centrifugal separation and vacuum drying to obtain the glycosaminoglycan. The method has the characteristics of low production cost, simple process and the like.

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Номер записи: 2
07-09-2011 дата публикации

Method and process for drying sodium hyaluronate finished product

Номер: CN0102174610A
Автор: ZHENWU ZHANG, FENGLIANG BA, HAIBIN ZHANG, LIANMING ZHU, GUIXIN JIANG, TAIMING ZHOU, ZHANG ZHENWU, BA FENGLIANG, ZHANG HAIBIN, ZHU LIANMING, JIANG GUIXIN, ZHOU TAIMING
Принадлежит:

The invention provides a method and a process for drying a sodium hyaluronate finished product. The finished product consists of starch, sucrose, beef extract, yeast powder, potassium dihydrogen sulfate, sodium hydroxide, water and defoaming oil. The method and the process comprise the following steps of: adding 15 to 25 milliliters of defoaming oil into the raw materials prepared in a ratio to culture, performing fermentation, flocculation, centrifugal separation, dissolution, filtration, precipitation and pulverization on the cultured seeds to obtain a hyaluronic acid finished product, pouring the hyaluronic acid finished product into a drying tank, heating the drying tank to the temperature of about 34 DEG C for drying, then cooling the drying tank to the temperature of between 0 and 5 DEG C, and continuously drying till the sodium hyaluronate finished product is obtained. The sodium hyaluronate finished product has the advantages of good uniformity, high yield, attractive appearance ...

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Номер записи: 3
17-08-2011 дата публикации

Dissolving method and process of coarse sodium hyaluronate

Номер: CN0102154403A
Автор: ZHENWU ZHANG, FENGLIANG BA, HAIBIN ZHANG, LIANMING ZHU, GUIXIN JIANG, TAIMING ZHOU, ZHANG ZHENWU, BA FENGLIANG, ZHANG HAIBIN, ZHU LIANMING, JIANG GUIXIN, ZHOU TAIMING
Принадлежит:

The invention provides a dissolving method and process of coarse sodium hyaluronate. The coarse sodium hyaluronate comprises starch, sucrose, beef extract, yeast powder, dialkyl potassium sulfate, sodium hydroxide, water and defoaming oil. 15-25 ml of defoaming oil is added to the raw materials which are proportionally mixed for culture and fermentation; after the fermentation, coarse hyaluronic acid is obtained by flocculating precipitation and centrifugal separation; the coarse hyaluronic acid, the deionized water and saline water are proportionally poured into a dissolving tank; the dissolving tank is heated to 60 DEG C, and the heat is preserved for more than 2 hours; and alcohol accounting for 10-15% of the total volume is added for dissolution. The dissolving method and process have the advantages that: the aldehyde acid content of the product is relatively high, and the product quality is greatly improved.

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Номер записи: 4
17-08-2011 дата публикации

Pre-fermentation seed culture method and feeding process for sodium hyaluronate

Номер: CN0102154402A
Автор: ZHENWU ZHANG, FENGLIANG BA, HAIBIN ZHANG, LIANMING ZHU, GUIXIN JIANG, TAIMING ZHOU, ZHANG ZHENWU, BA FENGLIANG, ZHANG HAIBIN, ZHU LIANMING, JIANG GUIXIN, ZHOU TAIMING
Принадлежит:

The invention provides a pre-fermentation seed culture method and a feeding process for sodium hyaluronate, which comprise the following steps of: adding 15 to 25 milliliters of defoaming oil into raw materials which are prepared according to a ratio and consist of starch, cane sugar, beef extract, yeast powder, potassium dialkyl sulfate, sodium hydroxide and water, dissolving by using proper amount of hot water, and pouring the mixture into a tank; and allowing seeds to grow in the tank for 12+/-0.5 hours, and pouring the seeds into a fermentation tank for fermenting, wherein phytic acid in an amount which is about 0.5 percent based on the total volume of the mixture is added before the seeds are poured into the fermentation tank. The method and the feeding process have the advantages that the yield of the prepared hyaluronic acid can be improved by over 1 percent, and the production benefits of enterprises are improved greatly.

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Номер записи: 5