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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 31. Отображено 31.
05-05-2005 дата публикации

Oral fluid sampling device and method

Номер: US20050096563A1
Автор: Greg Liang
Принадлежит:

A device for collecting an expectorated oral fluid specimen for testing comprises a collection chamber having a specimen reservoir space and a headspace, and a vent, and a hollow tube capable of conducting oral fluid from the oral fluid donor's mouth to the specimen reservoir space of the collection chamber. The headspace is for storing oral fluid foams and the vent is for air to escape the chamber when the oral fluid is being collected into the collection chamber. The tube and the collection chamber are either permanently connected or separate with the device having a connection mechanism allowing the connection of the two. The device may further comprise an assay reagent component for detecting an analayte of the oral fluid specimen. The device provides simple means for oral fluid collection and testing, and especially useful in point-of-collection testing of oral fluid specimens.

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10-08-2004 дата публикации

Electrical plug mechanism and electrical receptacle for electrical cell

Номер: US0006773289B1

A electrical plug mechanism and electrical receptacle is described. The present invention has an electrical plug, a plug guard and an electrical receptacle. The electrical plug has an end surface, and a plurality of protruding plates and a plurality of holes are defined on the end surface. A plurality of shafts correspond to and travel through the holes of the end surface. The plug guard has hollow protrusions corresponding to the protruding plates of the electrical plug, grooves corresponding to the hollow protrusions and holes corresponding to the shafts. The electrical receptacle has holders corresponding to the protruding plates.

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01-01-2009 дата публикации

Device for handling and analysis of a biological sample

Номер: US20090004058A1
Автор: Greg Liang, Kevin J. Kirby
Принадлежит:

An apparatus for detection of an analyte of interest in a solid, semi-solid, or liquid biological sample, using a lateral flow assay test strip, is described. The apparatus minimizes sample handling and manipulation upon introduction of the sample into a sample-receiving chamber and transfer of the sample to a test chamber containing the assay strip.

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14-08-2003 дата публикации

Integral sample collection tip

Номер: US20030153844A1
Принадлежит:

Assemblies are provided for collecting a sample from a mouth using an integrated sample collection tip. A sample collection assembly includes a sample collection body configured for being placed within the mouth, wherein the sample collection body includes a bore and one or more pores. The sample collection assembly further includes a conduit that disposed within the bore of the sample collection body and that is in fluid communication with the one or more pores. The conduit is bonded within the bore. The sample collection assembly can further include a hand piece that has a tip on which the sample collection body is mounted, and through which the conduit can extend. For example, the rear surface of the sample collection body can be bonded to the front surface of the sample collection tip. The pores can include a plurality of micropores. The sample collection body can be hydrophobic, and a hydrophilic surfactant can be disposed on the outer surface of the sample collection body.

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11-09-2003 дата публикации

Flow immunoassay assembly with rotary valve

Номер: US20030170145A1
Принадлежит:

Method and assemblies are provided for selectively distributing and dispensing fluids using a rotary valve for purposes such as performing immunoassay testing. A rotary valve includes a stator and rotor disposed within the stator. The rotor is clockable between a dispense configuration, a first auxiliary dispense configuration, and a second auxiliary dispense configuration. When the rotor is clocked in the dispense configuration, it includes a plurality of dispense channels connected between a plurality of entry dispense ports and a plurality of exit dispense ports disposed in the stator. When the rotor is clocked in the first auxiliary dispense configuration, the rotor includes a first plurality of auxiliary dispense channels connected between a plurality of auxiliary entry dispense ports disposed on the stator and the plurality of exit dispense ports. When the rotor is clocked in the second auxiliary dispense configuration, the rotor includes a second plurality of auxiliary dispense channels ...

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11-09-2003 дата публикации

Method of manufacturing a self-sealing chamber

Номер: US20030170882A1
Принадлежит:

Methods for manufacturing self sealing chambers by interference fitting barriers within the chambers are provided. A method of substantially sealing a chamber includes providing a die plate through which a channel extends and a compression plate through which a tapered channel extends. The tapered channel includes a first opening and a second opening opposite the first opening. The second opening is equal to or smaller than the chamber opening. The method further includes providing a chamber adapter that has a female portion and a passage extending therethrough, mating the chamber adapter female portion with a compression plate male portion, and associating the chamber with the chamber adapter passage, e.g., by disposing the chamber within the chamber adapter passage. The method further includes disposing a compressible material on the die plate and forming the barrier by pushing a pin through the compressible material into the die plate passage, and pushing the barrier into the first tapered ...

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18-01-2011 дата публикации

Rapid test apparatus

Номер: US0007871568B2

Provided herein are methods and devices for rapid testing of solid, semi-solid, or liquid specimens, such as stool, blood, urine, saliva, or swab specimens of the cervix, urethra, nostril, and throat, and for environmental testing.

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04-09-2003 дата публикации

Drug and alcohol assay assembly

Номер: US20030166264A1
Принадлежит: Individual

Assemblies and methods are provided for performing an assay on a sample for drugs and alcohol. A drug and alcohol assay assembly includes a sample feed port, and immunoassay reaction chamber containing a drug reagent, and a first sample flow channel in fluid communication between the sample feed port and the immunoassay reaction chamber. The assembly further includes an alcohol reaction chamber configured for containing an alcohol reagent, and a second sample flow channel in fluid communication between the sample feed port and the alcohol reaction chamber. The assembly can further include a first buffer flow channel in fluid communication with the immunoassay reaction chamber, a second buffer flow channel in fluid communication with the alcohol reaction chamber, and a reagent chamber disposed within the buffer flow channel. The reagent chamber can contain dry alcohol reagent. In this case, the alcohol reagent can include a reagent solution, where the reagent chamber is configured to produce the reagent solution for dispensing in the alcohol reaction chamber when buffer flows through the buffer flow channel. The drug reagent can be specific to one of the NIDA drugs-of-abuse.

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21-08-2003 дата публикации

Rotary valve with compliant lining

Номер: US20030155012A1
Принадлежит:

Rotary valves with rotors and compliant linings are provided. A rotary valve includes a rigid hollow stator and a rotor disposed within the stator. The rotor includes a rigid core and a compliant lining injection molded onto the rigid core, wherein the compliant lining is sealingly engaged with an inner bearing surface of the stator and includes one or more surface channels that can be placed into fluid communication with one or more ports disposed on the stator. The rigid core is composed of polycarbonate and the compliant lining is composed of polyurethane. The surface channels can be, e.g., arcuate or longitudinal surface channels. The rigid core can include one or more through channels, in which case, the one or more surface channels can intersect the one or more through channels to form a continuous channel.

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06-07-2006 дата публикации

Sampling device and methods

Номер: US20060147348A1
Автор: Greg Liang
Принадлежит:

Provided herein are methods of testing mucus for the presence of analytes, for example, drug analytes, and devices, kits, and methods for collecting test mucus samples.

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20-11-2008 дата публикации

SAMPLE COLLECTOR AND TESTER

Номер: US20080286831A1
Автор: Greg Liang
Принадлежит:

Provided are devices and methods for testing solid, semi-solid, or liquid animal or environmental specimens. The multi-part device comprises a breakable seal that separates a specimen treatment chamber from a testing chamber.

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25-09-2003 дата публикации

Hydrophobic/hydrophilic sample collection tip

Номер: US20030181826A1
Принадлежит:

Assemblies are provided for collecting oral fluid from a mouth of a subject using a hydrophobic/hydrophilic sample collection tip. A sample collection assembly includes a sample collection tip configured for being placed within the mouth, and a conduit in fluid communication with the sample collection tips. The sample collection tip includes a hydrophobic interior and a hydrophilic outer surface. In this manner, the tendency of analytes within the sample to stick to the interior of the sample collection tip is minimized, while allowing wetting of the outer surface of the sample collection tip with the sample to facilitate its collection. The sample collection assembly can further include a hand piece that has a tip on which the sample collection tip is mounted, and through which the conduit can extend. The sample collection tip can have a bore in which the conduit is disposed, e.g., by bonding. The hydrophobic interior of the sample collection tip can be composed of a microporous material ...

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28-06-2012 дата публикации

Rapid Test Apparatus

Номер: US20120164751A1
Принадлежит: Individual

Provided herein are methods and devices for rapid testing of solid, semi-solid, or liquid specimens, such a stool, blood, urine, saliva, or swab specimens of the cervix, urethra, nostril, throat, and for environmental testing.

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03-10-2002 дата публикации

Novel reagents for detecting cannabinoids

Номер: US20020142484A1
Принадлежит: LifePoint, Inc.

In this disclosure, novel caanabinol-based tracers suitable for use in immunoassays that detect cannabinoids in a biological sample are disclosed. These cannabinol-based tracers are particularly useful in a continuous flow displacement immunoassay. The disclosure also describes the processes for synthesizing the novel tracers, and the application of these tracers in fluorescence immunoassays for detecting and quantifying cannabinoids in biological samples.

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04-10-2005 дата публикации

Integral sample collection tip

Номер: US0006951545B2
Принадлежит: Lifepoint, Inc., LIFEPOINT INC, LIFEPOINT, INC.

Assemblies are provided for collecting a sample from a mouth using an integrated sample collection tip. A sample collection assembly includes a sample collection body configured for being placed within the mouth, wherein the sample collection body includes a bore and one or more pores. The sample collection assembly further includes a conduit that disposed within the bore of the sample collection body and that is in fluid communication with the one or more pores. The conduit is bonded within the bore. The sample collection assembly can further include a hand piece that has a tip on which the sample collection body is mounted, and through which the conduit can extend. The pores can include a plurality of micropores. The sample collection body can be hydrophobic, and a hydrophilic surfactant can be disposed on the outer surface of the sample collection body.

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26-05-2005 дата публикации

Flow assay device comprising dry reagent cake

Номер: US20050112023A1
Автор: Greg Liang
Принадлежит: Individual

The current invention provides an assay device for detecting an analyte in a sample solution comprising a first reagent chamber having a soluble reagent cake comprising a labeled reagent in fluid communication with an immobilized reagent section having an immobilized reagent, which is further in fluid communication with a fluid receiving section. The assay method using the device of the invention comprises applying a sample solution to the first reagent chamber, dissolving the reagent cake, and flowing the sample solution comprising the dissolved labeled reagent through the immobilized reagent section to the fluid receiving section of the device. The assay result is determined by reading a signal of the label of the labeled reagent at the immobilized reagent section or the fluid receiving section. The device preferably comprises a flow control mechanism between the first reagent chamber and the immobilized reagent section.

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11-09-2003 дата публикации

Tester for automated identification of analytes in bodily fluids

Номер: US20030171697A1
Принадлежит: Individual

A system, method, and assembly are provided for identifying one or more analytes within bodily fluids, such as saliva. The system includes an analyte tester, an oral aspirator, a conduit that is in fluid communication between the oral aspirator and the tester, and a pump in fluid communication with the conduit. In this manner, the aspirated oral fluid can be pumped directly from the aspirator into the analyte tester for identification of one or more oral fluid analytes. The analyte tester can be a flow immunoassay tester that identifies the five NIDA drugs-of-abuse, and can be configured to identify up to ten different drugs or other analytes. The analyte tester can also be portable, so that it can be conveniently used areas remote from laboratories. The tester may include a chemistry cassette and a test console configured for receiving the chemistry cassette. In this case, the conduit may be in fluid communication with the chemistry cassette. A user interface may also be provided for entering test information (e.g., a specific test selection or test panel customization) and for conveying test results (e.g., using a display or printer).

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03-02-2004 дата публикации

Reagents for detecting cannabinoids

Номер: US0006686209B2
Принадлежит: Lifepoint, Inc., LIFEPOINT INC, LIFEPOINT, INC.

In this disclosure, novel caanabinol-based tracers suitable for use in immunoassays that detect cannabinoids in a biological sample are disclosed. These cannabinol-based tracers are particularly useful in a continuous flow displacement immunoassay. The disclosure also describes the processes for synthesizing the novel tracers, and the application of these tracers in fluorescence immunoassays for detecting and quantifying cannabinoids in biological samples.

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14-09-2010 дата публикации

Device for handling and analysis of a biological sample

Номер: US0007794656B2

An apparatus for detection of an analyte of interest in a solid, semi-solid, or liquid biological sample, using a lateral flow assay test strip, is described. The apparatus minimizes sample handling and manipulation upon introduction of the sample into a sample-receiving chamber and transfer of the sample to a test chamber containing the assay strip.

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21-08-2003 дата публикации

Flow immunoassay scanning assembly

Номер: US20030157480A1
Принадлежит:

Methods and assemblies are provided for scanning a flow immunoassay assembly. A flow immunoassay scanning assembly includes a plurality of immunoassay reaction chambers, a plurality of read cells in fluid communication with the plurality of immunoassay reaction chambers, a detector having a sensing beam, and a scanning drive assembly configured to translate the detector to intersect the plurality of read cells with the sensing beam. The detector includes an optical detector, and each of the immunoassay reaction chambers contains fluorescent labeled antigen that is displaced when an analog to the fluorescent labeled antigen flows through the immunoassay reaction chamber. Thus, the fluorescent labeled antigen can be detected by the optical detector when flowed through the corresponding read cell. The detector can also be configured, such that the sensing beam intersects the plurality of read cells at an angle substantially perpendicular to the longitudinal axes of the read cells. The scanning ...

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28-08-2003 дата публикации

Alcohol detection assembly

Номер: US20030162204A1
Принадлежит:

Assemblies and methods are provided for detecting alcohol using a reconstituted reagent solution. An alcohol reaction assembly includes an alcohol reaction chamber, a reagent chamber in fluid communication with the alcohol reaction chamber, and a buffer chamber in fluid communication with the reagent chamber. The alcohol reaction assembly further includes a buffer dispense plunger disposed within the buffer chamber for dispensing buffer from the buffer chamber, through the reagent chamber, and into the alcohol reaction chamber, where it hydrates dry reagent therein to produce a reagent solution. The alcohol reaction assembly further includes a calibrator chamber in fluid communication with the alcohol reaction chamber, and a calibrator dispense plunger disposed within the calibrator chamber to dispense a predetermined quantity of alcohol into the alcohol reaction chamber. The alcohol reaction assembly also includes a sample chamber in fluid communication with the alcohol reaction chamber ...

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04-09-2003 дата публикации

Method for accurately mixing sample and buffer solutions

Номер: US20030166259A1
Принадлежит:

Methods for accurately mixing two solutions, e.g., buffer and sample solutions, are provided. A method of mixing first and second fluids using first, second, and third chambers includes selecting a fluid mixture r, providing the first chamber with a first cross-sectional area A1, providing the third chamber with a second cross-sectional area A2, disposing the first fluid in the first chamber, disposing the second fluid in the second chamber, moving a first plunger within the first chamber at a speed S1towards a first port to dispense the first solution from the first chamber into the third chamber, and moving a second plunger substantially simultaneously with the first plunger within the third chamber at a speed S2away from the second port to dispense the second solution from the second chamber into the third chamber, wherein A2S2=A1S1(1+1/r). The sample and buffer can be mixed, in which case, the first, second, and third chambers can be buffer, sample collection, and mixing chambers, and ...

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08-05-2008 дата публикации

Split Sample Test Chamber Device

Номер: US20080105066A1
Автор: Greg Liang
Принадлежит: Individual

A device for testing a sample solution comprising a test chamber comprising a test component enclosed with air impermeable casing, a sample inlet distal from the test component capable of being connected to a sample solution and, in a test position, maintaining at higher altitude than the liquid level within the test chamber, a sealable air vent distal from the sample inlet capable of permitting air to exit the test chamber when a sample solution flows into the test chamber through the sample inlet and being closed by a sealing means and stopping sample inflow through the sample inlet when sufficient sample solution flows into the test chamber and before the liquid level within the test chamber reaches the level of the sample inlet. The device is useful for testing a portion of a sample solution without contaminating the remaining portion of the sample solution.

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21-08-2003 дата публикации

Automated plunger-based sample/buffer mixing assembly

Номер: US20030158499A1
Принадлежит:

Assemblies and methods are provided for mixing a sample and a buffer. A sample/buffer mixing assembly includes a sample collection chamber, a buffer chamber containing a buffer, a mixing chamber, and one or more plungers. The sample collection chamber is in fluid communication with a sample collection interface device. The mixing chamber includes a sample port adjacent the sample collection chamber, and a buffer port adjacent the buffer chamber. The plungers are in fluid communication with the sample collection chamber and the buffer chamber, and can be moved to dispense the buffer from the buffer chamber into the mixing chamber via the sample port, and the sample from the sample collection chamber into the mixing chamber via the buffer port. In this manner, the dispensed sample and buffer form a buffered sample solution within the mixing chamber. The plungers can include a buffer dispense plunger that is movable within the buffer chamber towards the buffer port to dispense the buffer from ...

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28-08-2003 дата публикации

Orthogonal read assembly

Номер: US20030162308A1
Принадлежит:

Methods and assemblies are provided for transmitting and detecting energy within a read cell. An orthogonal read assembly includes an immunoassay reaction chamber, a read cell having a lumen in fluid communication with the immunoassay reaction chamber, a transmitter configured to transmit energy through the lumen, and a detector configured to sense energy emitted transversely from the lumen. The transmitter can include an optical transmitter, such as a laser, and the detector can include an optical detector, e.g., a silicon diode. The optical transmitter can transmit optical energy at an oblique entry angle to the lumen, e.g., 45°, and the optical energy can be sensed by the optical detector at an angle substantially perpendicular to the lumen. The read cell can be composed of a transparent plastic and can be parallel-pipe shaped. The lumen can be cylindrically shaped and may include an optical transmission port, in which case, the optical transmitter can be configured to transmit the optical ...

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18-09-2003 дата публикации

Flow immunoassay assembly with multiple flow channels

Номер: US20030175820A1
Принадлежит:

Methods and assemblies are provided for flowing a single sample through a plurality of immunoassay reaction chambers. A flow immunoassay assembly for testing a single sample, includes a sample feed port, a plurality of immunoassay reaction chambers for performing a plurality of different assays on the sample, a plurality of sample flow channels in fluid communication between the sample feed port and the plurality of immunoassay reaction chambers, and one or more sample drive assemblies configured to pump the sample through the plurality of sample flow channels into the plurality of immunoassay reaction chambers. In this manner, several immunoassay tests can be simultaneously performed on the sample. The immunoassay assembly can further include a plurality of buffer flow channels in fluid communication with the plurality of immunoassay reaction chambers, and one or more buffer drive assemblies configured to pump the buffer through the plurality of buffer flow channels into the plurality ...

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21-08-2003 дата публикации

Plunger-based flow immunoassay assembly

Номер: US20030157564A1
Принадлежит:

Assemblies and methods are provided for flowing sample through a flow immunoassay assembly using one or more plungers. The flow immunoassay assembly includes an immunoassay reaction chamber, a sample distribution chamber in fluid communication with the immunoassay reaction chamber, and a sample dispense plunger being movable within the sample distribution chamber to dispense the sample from the sample distribution chamber into the immunoassay reaction chamber. The flow immunoassay assembly can further include a buffer chamber in fluid communication with the immunoassay reaction chamber, and a buffer dispense plunger movable within the buffer chamber to dispense buffer from the buffer chamber into the immunoassay reaction chambers. The flow immunoassay assembly can further include a read cell in fluid communication with the immunoassay reaction chamber for providing a means to measure a reaction within the reaction chamber (which may be a displacement type immunoassay reaction chamber) and ...

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29-11-2007 дата публикации

Rapid Test Apparatus

Номер: US20070275475A1
Автор: Greg Liang
Принадлежит:

Provided herein are methods and devices for rapid testing of solid, semi-solid, or liquid specimens, such as stool, blood, urine, saliva, or swab specimens of the cervix, urethra, nostril, and throat, and for environmental testing.

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21-05-2002 дата публикации

Device for detecting analytes related to sample pH

Номер: US0006391261B1
Принадлежит: Lifepoint, Inc., LIFEPOINT INC, LIFEPOINT, INC.

A device for measuring, concurrently from the same sample solution, the pH and presence or quantity of an analyte in the solution. The pH and analyte measuring sections of the invention are contained within the same holding structure.

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19-09-2002 дата публикации

Novel reagents for detecting cannabinoids

Номер: CA2441189A1
Принадлежит: Individual

In this disclosure, novel cannabinol-based tracers suitable for use in immunoassays that detect cannabinoids in a biological sample are disclosed. These cannabinol-based tracers are particularly useful in a continuous flow displacement immunoassay. The disclosure also describes the processes for synthesizing the novel tracers, and the application of these tracers in fluorescence immunoassays for detecting and quantifying cannabinoids in biological samples. The cannabind-based tracer has lower affinity for antibodies to .DELTA.9~ -THC and is more effectively displaced when a THC containing sample is applied. This results in higher sensitivity.

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24-07-2008 дата публикации

Sample collector and tester

Номер: WO2008089198A1
Автор: Greg Liang
Принадлежит: Greg Liang

Provided are devices and methods for testing solid, semi- solid, or liquid animal or environmental specimens. The multi-part device comprises a breakable seal that separates a specimen treatment chamber from a testing chamber.

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