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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 13. Отображено 13.
03-11-2010 дата публикации

Cresol trimer compounds as well as preparation method and application thereof

Номер: CN0101875601A
Автор: WEIMING ZHU, YIBIN ZHUANG, KUI HONG, ZHENYU LU, ZHIHUA ZHANG, HAIPENG LIN, YI WANG, PEIPEI LIU, PENG FU, ZHU WEIMING, ZHUANG YIBIN, HONG KUI, LU ZHENYU, ZHANG ZHIHUA, LIN HAIPENG, WANG YI, LIU PEIPEI, FU PENG
Принадлежит:

The invention relates to cresol trimer compounds as well as a preparation method and application thereof. The compounds with novel structure are prepared from Penicillium expansum 091006 separated from a root sample of Excoecaria agallocha which is a mangrove plant. Proved by experiments, the compounds can be used as a cell proliferation inhibitor or antitumor agent.

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Номер записи: 1
08-02-2012 дата публикации

Application of 2-acetylamino gentisic acid to preparing insulin sensitizer

Номер: CN0101919835B
Автор: XINSHENG YAO, JIA LI, KUI HONG, JINSHAN TANG, HAO GAO, LIXIN GAO, HAIPENG LIN, XUERONG ZENG, LI SHENG, LING ZHUANG, YAO XINSHENG, LI JIA, HONG KUI, TANG JINSHAN, GAO HAO, GAO LIXIN, LIN HAIPENG, ZENG XUERONG, SHENG LI, ZHUANG LING
Принадлежит:

The invention discloses application of a 2-acetylamino gentisic acid compound with protein tyrosine phosphatase 1B inhibitory activity to preparing an insulin sensitizer. The 2-acetylamino gentisic acid can be used for preparing drugs for treating diabetes, obesity and complications thereof caused by insulin resistance and is obtained by fermenting and separating deep-sea streptomyces sp. 220225.

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Номер записи: 2
22-12-2010 дата публикации

Application of aromatic compounds in preparing Caspase 3 inhibitor

Номер: CN0101919833A
Автор: XINSHENG YAO, KUI HONG, JIA LI, HAO GAO, JINSHAN TANG, HAIPENG LIN, LIXIN GAO, GUODONG CHEN, QINGYI XIE, LI SHENG, YAO XINSHENG, HONG KUI, LI JIA, GAO HAO, TANG JINSHAN, LIN HAIPENG, GAO LIXIN, CHEN GUODONG, XIE QINGYI, SHENG LI
Принадлежит:

The invention discloses an application of aromatic compounds in preparing a Caspase 3 inhibitor which is used in preparing drugs for curing diseases such as neurodegenerative diseases, ischemic symptoms, sepsis and the like caused by Caspase 3 over expression, wherein the neurodegenerative diseases refer to Alzheimer's disease, parkinsonism or Huntington's disease; and the ischemic symptoms refer to stroke or myocardial infarction. The aromatic compounds can be obtained by fermenting and separating actinomycetes.

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Номер записи: 3
30-05-2012 дата публикации

Application of styrene phenol compounds to preparing insulin sensitizer

Номер: CN0101953820B
Автор: XINSHENG YAO, JIA LI, KUI HONG, JINSHAN TANG, HAO GAO, LIXIN GAO, HAIPENG LIN, XUERONG ZENG, LI SHENG, LING ZHUANG, YUANYUAN LI, YAO XINSHENG, LI JIA, HONG KUI, TANG JINSHAN, GAO HAO, GAO LIXIN, LIN HAIPENG, ZENG XUERONG, SHENG LI, ZHUANG LING, LI YUANYUAN
Принадлежит:

The invention discloses application of styrene phenol compounds with the inhibition activity of protein tyrosine phosphatases 1B and the structure shown as the formula (I) to preparing an insulin sensitizer. The insulin sensitizer is applied to preparing medicaments for treating diabetes mellitus, obesity and complications thereof caused by the insulin resistance. The styrene phenol compounds can be obtained by fermenting and separating streptomyces sp.220225.

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Номер записи: 4
22-12-2010 дата публикации

Application of 2-acetylamino gentisic acid to preparing insulin sensitizer

Номер: CN0101919835A
Автор: XINSHENG YAO, JIA LI, KUI HONG, JINSHAN TANG, HAO GAO, LIXIN GAO, HAIPENG LIN, XUERONG ZENG, LI SHENG, LING ZHUANG, YAO XINSHENG, LI JIA, HONG KUI, TANG JINSHAN, GAO HAO, GAO LIXIN, LIN HAIPENG, ZENG XUERONG, SHENG LI, ZHUANG LING
Принадлежит:

The invention discloses application of a 2-acetylamino gentisic acid compound with protein tyrosine phosphatase 1B inhibitory activity to preparing an insulin sensitizer. The 2-acetylamino gentisic acid can be used for preparing drugs for treating diabetes, obesity and complications thereof caused by insulin resistance and is obtained by fermenting and separating deep-sea streptomyces sp. 220225.

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Номер записи: 5
19-01-2011 дата публикации

Novel staurosporine analogue and preparation method and applications thereof

Номер: CN0101948472A
Автор: KUI HONG, WEIMING ZHU, CHUNLI YANG, JINLEI SUI, HAIPENG LIN, XIAOXIONG XU, YI WANG, HONG KUI, ZHU WEIMING, YANG CHUNLI, SUI JINLEI, LIN HAIPENG, XU XIAOXIONG, WANG YI
Принадлежит:

The invention relates to a novel staurosporine analogue and a preparation method and applications thereof, wherein two staurosporine analogue molecules with a novel structure is prepared from the Streptomyces Sp.FMA which is separated from the soil sample of the Sanya Mangrove in Hainan Island of China and has the strain preservation number of CCTCC M 2010021. The in vitro cytotoxicity test proves that the compound has cytotoxicity to leukemia cell HL-60 and lung cancer cell A549 and can be used as the cell antiblastic.

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Номер записи: 6
29-09-2010 дата публикации

Quinazoline ketones alkaloid and preparation method and application thereof

Номер: CN0101845021A
Автор: HAICHAO FU, KUI HONG, HAIPENG LIN, PEIPEI LIU, YOU WANG, CHUN XIAO, ZHIHONG XU, YAPENG ZHANG, WEIMING ZHU, FU HAICHAO, HONG KUI, LIN HAIPENG, LIU PEIPEI, WANG YOU, XIAO CHUN, XU ZHIHONG, ZHANG YAPENG, ZHU WEIMING
Принадлежит:

The invention relates to quinazoline ketones alkaloid and a preparation method and application thereof; in the invention, separation is carried out in a sea mud sample from offshore Baima Jingzhen in Danzhou in Hainan to obtain bacterium-Baxillus ereus 041381, and the compounds with novel structure are produced by the bacteria with culture preservation number CCTCC M 203030, and the compounds are prepared by a chemical synthesis method; proved by experiments, the compounds have candida albicans resisting activity, the minimum inhibition concentration MIC is 1.3-10.2mum, therefore, the compounds can be used as inhibitors of candida albicans.

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Номер записи: 7
04-07-2012 дата публикации

Novel staurosporine analogue and preparation method and applications thereof

Номер: CN0101948472B
Автор: KUI HONG, WEIMING ZHU, CHUNLI YANG, JINLEI SUI, HAIPENG LIN, XIAOXIONG XU, YI WANG, HONG KUI, ZHU WEIMING, YANG CHUNLI, SUI JINLEI, LIN HAIPENG, XU XIAOXIONG, WANG YI
Принадлежит:

The invention relates to a novel staurosporine analogue and a preparation method and applications thereof, wherein two staurosporine analogue molecules with a novel structure is prepared from the Streptomyces Sp.FMA which is separated from the soil sample of the Sanya Mangrove in Hainan Island of China and has the strain preservation number of CCTCC M 2010021. The in vitro cytotoxicity test proves that the compound has cytotoxicity to leukemia cell HL-60 and lung cancer cell A549 and can be used as the cell antiblastic.

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Номер записи: 8
19-01-2011 дата публикации

Method for producing alpha-acetolacetate decearboxylase by using integrated recombinant bacillus subtilis as strain

Номер: CN0101948821A
Автор: XIAOMING LI, DONGQING LIAO, TIANFANG YUE, QINGYAN WANG, RIBO HUANG, JIANZONG MENG, HAIPENG LIN, CONG LI, ZILONG WANG, SHAOMIN MA, FAZHONG CHEN, YUNGUANG ZHANG, LIANHUA LIANG, ZHAOFEI LUO, LI XIAOMING, LIAO DONGQING, YUE TIANFANG, WANG QINGYAN, HUANG RIBO, MENG JIANZONG, LIN HAIPENG, LI CONG, WANG ZILONG, MA SHAOMIN, CHEN FAZHONG, ZHANG YUNGUANG, LIANG LIANHUA, LUO ZHAOFEI
Принадлежит:

The invention discloses a method for producing alpha-acetolacetate decearboxylase by using integrated recombinant bacillus subtilis as a strain. The method comprises the following steps of: integrating an alpha-acetolacetate decearboxylase expression element to a bacillus subtilis chromosome to construct the integrated recombinant bacillus subtilis which serves as the strain, and producing the alpha-acetolacetate decearboxylase by fermentation in a nutrient medium. The method has the advantages that: the alpha-acetolacetate decearboxylase is produced by using a food safety expression system, the exogenous gene contained in the strain of integrated expression can stabilize passage and expression, and the product meets the food requirement and has no antibacterial activity.

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Номер записи: 9
26-01-2011 дата публикации

Application of styrene phenol compounds to preparing insulin sensitizer

Номер: CN0101953820A
Автор: XINSHENG YAO, JIA LI, KUI HONG, JINSHAN TANG, HAO GAO, LIXIN GAO, HAIPENG LIN, XUERONG ZENG, LI SHENG, LING ZHUANG, YAO XINSHENG, LI JIA, HONG KUI, TANG JINSHAN, GAO HAO, GAO LIXIN, LIN HAIPENG, ZENG XUERONG, SHENG LI, ZHUANG LING
Принадлежит:

The invention discloses application of styrene phenol compounds with the inhibition activity of protein tyrosine phosphatases 1B and the structure shown as the formula (I) to preparing an insulin sensitizer. The insulin sensitizer is applied to preparing medicaments for treating diabetes mellitus, obesity and complications thereof caused by the insulin resistance. The styrene phenol compounds can be obtained by fermenting and separating streptomyces sp.220225.

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Номер записи: 10
04-08-2010 дата публикации

Novel AzalomycinF microlide compounds and preparation method thereof and application thereof

Номер: CN0101792474A
Автор: KUI HONG, XIAOLONG HUANG, HAIPENG LIN, YILI TANG, CHENG WANG, QINGYI XIE, GANJUN YUAN, HONG KUI, HUANG XIAOLONG, LIN HAIPENG, TANG YILI, WANG CHENG, XIE QINGYI, YUAN GANJUN
Принадлежит:

The invention discloses novel AzalomycinF microlide compounds and a preparation method thereof and application thereof. The invention aims to provide novel compounds having a unique structure and having broad-spectrum yeast fungus, banana vascular wilt and root-knot nematode resistant activities. The compounds provided by the invention are characterized by the compounds having a framework structure of a formula I or formula II, wherein R1 in the formula I is alkanoyl or alkoxylacylacetyl, R2 is hydrogen or methyl, R3 is hydrogen or methyl; and in the formula II, R1 is the alkanoyl or the alkoxylacylacetyl, R2 is the hydrogen or the methyl, R3 is the hydrogen or the methyl.

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Номер записи: 11
11-01-2012 дата публикации

Application of aromatic compounds in preparing Caspase 3 inhibitor

Номер: CN0101919833B
Автор: XINSHENG YAO, KUI HONG, JIA LI, HAO GAO, JINSHAN TANG, HAIPENG LIN, LIXIN GAO, GUODONG CHEN, QINGYI XIE, LI SHENG, YAO XINSHENG, HONG KUI, LI JIA, GAO HAO, TANG JINSHAN, LIN HAIPENG, GAO LIXIN, CHEN GUODONG, XIE QINGYI, SHENG LI
Принадлежит:

The invention discloses an application of aromatic compounds in preparing a Caspase 3 inhibitor which is used in preparing drugs for curing diseases such as neurodegenerative diseases, ischemic symptoms, sepsis and the like caused by Caspase 3 over expression, wherein the neurodegenerative diseases refer to Alzheimer's disease, parkinsonism or Huntington's disease; and the ischemic symptoms refer to stroke or myocardial infarction. The aromatic compounds can be obtained by fermenting and separating actinomycetes.

Подробнее
Номер записи: 12
02-02-2011 дата публикации

Novel oxygen heterocyclic compound, salt thereof and preparation method and application of both

Номер: CN0101962370A
Автор: KUI HONG, GANJUN YUAN, HAIPENG LIN, QINGYI XIE, CHENG WANG, HONG KUI, YUAN GANJUN, LIN HAIPENG, XIE QINGYI, WANG CHENG
Принадлежит:

The invention relates to a novel oxygen heterocyclic compound and salt thereof according to the general formula I, wherein R1 is oxygen, alkyl radical or aromatic radical, R2 is hydrogen, alkyl radical or aromatic radical, R3 is hydrogen, alkyl radical or alkanoyl, R4 is hydrogen, alkyl radical or alkanoyl, R5 is hydrogen, alkyl radical or alkanoyl and R6 is hydrogen, alkyl radical or alkanoyl. The invention also relates to the preparation method of the compound and the salt thereof and the application of the compound and the salt thereof in preparing antibacterial agent. The formula I is shown as follows.

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Номер записи: 13