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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 15. Отображено 15.
08-08-2023 дата публикации

Synthesis method of alpha-alkoxy p-chlorobenzyl phosphate

Номер: CN116554221A
Автор: GUO JIANFA, WANG TAO, HAN HAIPING, KONG QIANGUANG, DONG JIANSHENG
Принадлежит:

The invention provides a synthesis method of alpha-alkoxy p-chlorobenzyl phosphate ester. According to the synthesis method, p-chlorobenzylidene dichloride (I) and phosphite (II) are adopted as raw materials, the alpha-alkoxy p-chlorobenzyl phosphate (III) is obtained through one-step condensation under the condition of sodium alcoholate, and the technological method has the advantages that the raw materials are cheap and easy to obtain, the yield is high, the cost is low, the reaction conditions are mild, and the technological method is suitable for industrial large-scale production.

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Номер записи: 1
07-04-2023 дата публикации

Novel synthesis method of trifloxystrobin intermediate

Номер: CN115925578A
Автор: WANG TAO, HAN HAIPING, KONG QIANGUANG, GUO JIANFA, DONG JIANSHENG
Принадлежит:

The invention relates to a novel synthesis method of a trifloxystrobin intermediate. The method comprises the following steps: 1, oximating and etherifying benzyl cyanide and nitrite ester under an alkaline condition; 2, the finished product in the step 1 and formaldehyde are subjected to ring closing under the acidic condition; 3, enabling the finished product in the step 2 to react with thionyl chloride under the condition of methanol to directly obtain the trifloxystrobin key intermediate (2-chloromethyl-alpha-methoxyimino methyl phenylacetate). The preparation method provided by the invention has the advantages of cheap and easily available raw materials, mild reaction conditions and simple and smooth process, and compared with synthesis methods reported in other literatures, the preparation method provided by the invention adopts cheap benzyl cyanide as a raw material and adopts a strategy of chloro groups on thionyl chloride, so that the raw material cost is greatly reduced, the technical ...

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Номер записи: 2
04-08-2023 дата публикации

Green and efficient synthesis method of 1-(4-chlorphenyl)-4, 4-dimethyl-3-pentanone

Номер: CN116535301A
Автор: GUO JIANFA, LI PENGTAO, WANG TAO, HAN HAIPING, KONG QIANGUANG, DONG JIANSHENG
Принадлежит:

The invention provides a green and efficient synthesis method of 1-(4-chlorphenyl)-4, 4-dimethyl-3-pentanone, which comprises the following steps: taking p-chlorobenzyl chloride and pinacolone as raw materials, and directly synthesizing in the presence of a catalyst and alkali to obtain a bactericide tebuconazole key intermediate 1-(4-chlorphenyl)-4, 4-dimethyl-3-pentanone. According to the synthesis method, p-chlorobenzyl chloride is taken as an initial raw material, p-chlorobenzaldehyde is not required to be firstly prepared through chlorination hydrolysis, and then p-chlorobenzaldehyde and pinacolone are subjected to condensation and hydrogenation to obtain 1-(4-chlorphenyl)-4, 4-dimethyl-3-pentanone, instead, p-chlorobenzyl chloride and pinacolone are directly taken as initial raw materials, and a target product 1-(4-chlorphenyl)-4, 4-dimethyl-3-pentanone is obtained through one-step synthesis. And the catalyst is 2, 4-dimethyl-3-pentanone. According to the synthetic method of the 1 ...

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Номер записи: 3
01-04-2015 дата публикации

Imidazolone compound as well as preparation method and application of imidazolone compounds serving as pesticidebactericide

Номер: CN104478807A
Автор: YE ZHENJUN, KUANG DONG, BI QIANG, DONG JIANSHENG, HAN HAIPING, ZHANG HONGYU, WU QINGYANG, ZHANG ZHIPING, ZHANG ZHONGMING, WANG LIANYU, FANG YAN, HUANG FAN
Принадлежит:

The invention provides an imidazolone compound. The imidazolone compound is acompound represented as the structural formula (I),pharmaceuticallyacceptable salt of the compound, any optical isomer or any tautomer shown in the specification. The invention further provides a preparation method of the imidazolone compound. The imidazolone compoundrepresented as formula (I) is prepared through reaction of a phenylhydrazine compound represented as a structural formula (II) or salt of the phenylhydrazine compound, a structure represented by a structural formula (III) and methyl iodide, and the reaction formula is shown in the specification. The preparation method of the imidazolone compounds (I) is simple, the reaction condition is mild, the product purity is high, and the yield is high. The invention further provides pesticidebactericide composition comprising bacteriostatic activity ingredients of the imidazolone compound. The pesticidebactericide composition particularly has a remarkable activity ...

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Номер записи: 4
07-07-2023 дата публикации

Efficient synthesis method of 1-(4-chlorphenyl)-2-cyclopropyl-1-acetone

Номер: CN116396151A
Автор: WANG ZHENGRONG, WANG TAO, HAN HAIPING, KONG QIANGUANG, DONG JIANSHENG
Принадлежит:

The invention relates to a high-efficiency synthesis method of 1-(4-chlorphenyl)-2-cyclopropyl-1-acetone, which comprises the following steps: Step 1: by taking p-chlorobenzyl cyanide and cyclopropyl methyl ketone as main raw materials, adding halogen on the benzyl position of the p-chlorobenzyl cyanide; step 2, carrying out a Darzen reaction with cyclopropyl methyl ketone under an alkaline condition to obtain an epoxide; and Step 3: carrying out cyano hydrolysis under an acidic condition, and carrying out deacidification to obtain the target product 1-(4-chlorphenyl)-2-cyclopropyl-1-acetone. P-chlorobenzyl cyanide and cyclopropyl methyl ketone are used as main raw materials, p-chlorobenzyl cyanide is subjected to halogenation at a benzyl position and then subjected to a Darzen reaction with cyclopropyl methyl ketone under the alkaline condition to obtain an epoxide, a target product is obtained through one-pot cyano hydrolysis and deacidification under the acidic condition, the synthesis ...

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Номер записи: 5
07-07-2023 дата публикации

Synthesis method of 1-(4-chlorphenyl)-2-cyclopropyl-1-acetone

Номер: CN116396155A
Автор: GUO JIANFA, WANG TAO, HAN HAIPING, KONG QIANGUANG, DONG JIANSHENG
Принадлежит:

The invention relates to a synthesis method of 1-(4-chlorphenyl)-2-cyclopropyl-1-acetone. The method comprises the following steps: step 1, carrying out addition elimination on a p-chlorobenzyl halide metal reagent and cyclopropyl methyl ketone to obtain an olefin compound; step 2: carrying out halogen addition reaction to obtain a formula (II); 3, elimination and hydrolysis are carried out under the alkaline condition, acidification and rearrangement are carried out under the acidic condition, and the target product 1-(4-chlorphenyl)-2-cyclopropyl-1-acetone is obtained. The p-chlorobenzyl halide metal reagent and the cyclopropyl methyl ketone are subjected to addition elimination to obtain the olefin compound, then halogen addition, hydrolysis elimination under the alkaline condition and acidic rearrangement are performed to obtain the target product, and the synthesis method is safe and environment-friendly, high in yield, low in raw material cost, mild in synthesis reaction condition ...

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Номер записи: 6
25-03-2015 дата публикации

Method for synthesizing 1-chloro-1-chloroacetyl-cyclopropane by adopting one-pot reaction

Номер: CN104447262A
Автор: YE ZHENJUN, KUANG DONG, ZHANG ZHIPING, ZHANG HONGYU, HAN HAIPING, WU QINGYANG, ZHANG ZHONGMING, WANG LIANYU, FANG YAN, HUANG FAN
Принадлежит:

The invention provides a method for synthesizing 1-chloro-1-chloroacetyl-cyclopropane by adopting one-pot reaction. The synthetic method adopted by the invention is a method for synthesizing the 1-chloro-1-chloroacetyl-cyclopropane by adopting one-pot reaction. The method is short in steps, low in usage of equipment, moderate in operation condition, high in product selectivity and simple in after-treatment, can be used for preparing the 1-chloro-1-chloroacetyl-cyclopropane of which the content is 97% by distillation, and has an industrial production prospect.

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Номер записи: 7
01-05-2018 дата публикации

Selectivity preparation system of pyrrole propyl ether midbody result alcohol ether

Номер: CN0207294644U
Автор: YE ZHENJUN, BI QIANG, HUANG WENRUI, HAN HAIPING, FANG YAN, XU HAIYAN, ZHANG ZHIPING
Принадлежит: SHANGHAI SHENGNONG PESTICIDE CO LTD, SHANGHAI SHENGNONG PESTICIDE CO., LTD.

The utility model relates to a selectivity preparation system of pyrrole propyl ether midbody result ether alcohol, include the synthetic cauldron of a high -pressure stainless steel alcohol ether, the dropwise add device, nitrogen protective device and the back processing apparatus that link to each other with the synthetic cauldron of alcohol ether, the dropwise add device includes the epoxypropane metering tank, the drop tube way that the output of epoxypropane metering tank passes through epoxypropane links to each other with the input of synthetic cauldron, nitrogen protective device including each other the nitrogen gas supply unit and the connecting pipe of intercommunication, nitrogen gas entry linkage on connecting pipe and the reation kettle, back processing apparatus includes centrifuge and waste liquid receipt jar, the output of centrifuge and synthetic cauldron link to each other, the input that the waste liquid was received jar links to each other with centrifuge. The utility ...

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Номер записи: 8
01-08-2023 дата публикации

Synthesis method of alpha-chloro-p-chlorobenzyl phosphate

Номер: CN116514866A
Автор: GUO JIANFA, WANG TAO, HAN HAIPING, KONG QIANGUANG, DONG JIANSHENG
Принадлежит:

The invention provides a synthesis method of alpha-chloro p-chlorobenzyl phosphate ester. According to the synthesis method, p-chlorobenzylidene dichloride (I) and phosphite (II) are adopted as raw materials and are directly condensed under the alkaline condition to obtain alpha-chloro p-chlorobenzyl phosphate (III), and the process method has the advantages of cheap and easily available raw materials, high yield, low cost and mild reaction conditions, and is suitable for industrial large-scale production.

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Номер записи: 9
29-08-2023 дата публикации

Method for synthesizing cyproconazole from cyproconazole 4H isomer

Номер: CN116655547A
Автор: WANG ZHENGRONG, WANG TAO, HAN HAIPING, KONG QIANGUANG, DONG JIANSHENG
Принадлежит:

The invention relates to a method for synthesizing cyproconazole from a cyproconazole 4H isomer, which comprises the following steps: Step 1: taking the cyproconazole 4H isomer and 2-(4-chlorphenyl)-3-cyclopropyl-1-(4H-1, 2, 4-triazole-1-yl) butyl-2-alcohol as a compound 1, adding the compound 1 into a solvent, and adding a certain amount of MOFs (Metal-Organic Frameworks) immobilized ionic liquid; step 2: keeping the temperature for a period of time under a certain temperature condition; step 3: filtering and recovering the catalyst MOFs immobilized ionic liquid, desolventizing the filtrate, and adding a solvent for pulping; and step 4, filtering and drying to obtain the product cyproconazole. The preparation method disclosed by the invention is simple to operate, smooth in process, mild in condition, green and environment-friendly, good in atom economy, high in raw material conversion rate and high in product yield, the catalyst can be repeatedly utilized, the problem that an isomer cannot ...

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Номер записи: 10
25-03-2015 дата публикации

Method for synthesizing chloronitropyridine methyleneimidazolidine through one-pot process

Номер: CN104447690A
Автор: YE ZHENJUN, ZHANG HONGYU, BI QIANG, FANG YAN, WANG LIANYU, HAN HAIPING, KUANG DONG, WU QINGYANG, ZHANG ZHONGMING, HUANG FAN, ZHANG ZHIPING
Принадлежит:

The invention provides a method for synthesizing chloronitropyridine methyleneimidazolidine through a one-pot process. The synthetic method adopted in the invention is characterized in that the structural formula is as shown in the specification, chloronitropyridine methyleneimidazolidine is synthesized by virtue of the one-pot process, the intermediate of the reaction in each step does not need to be separated and purified, the operations of all synthesis units are finished in the same reaction kettle, the equipment utilization rate is high, the after-treatment process is simple and convenient, the operation conditions are mild, and the three wastes are greatly reduced. The product is recrystallized by virtue of an organic solvent, the content of the product is 98 percent, and the method has good industrial production prospects.

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Номер записи: 11
22-04-2015 дата публикации

Method for synthesizing 3,4,5-trifluoro-2'-nitrobiphenyl

Номер: CN104529786A
Автор: YE ZHENJUN, HAN HAIPING, WANG LIANYU, BI QIANG, HUANG FAN, ZHANG ZHIPING, KUANG DONG, ZHANG HONGYU, WU QINGYANG, ZHANG ZHONGMING, FANG YAN
Принадлежит:

The invention provides a method for synthesizing 3,4,5-trifluoro-2'-nitrobiphenyl; a synthetic route is as shown in the description, wherein -X represents a substituent group selected from one of -Cl, -Br, -I, COOH, -N2Cl and -N2HSO4. The method comprises the following steps of (1), dissolving the raw materials including 3,4,5-trifluorobenzeneboronic acid and ortho-nitro substituted benzene in a solvent, and adding a catalyst and an acid-binding agent; (2), reacting while stirring till finishing; (3), washing, and extracting to obtain an organic phase; and (4), concentrating, and recrystallizing to obtain 3,4,5-trifluoro-2'-nitrobiphenyl. According to the invention, the Ms-Pd catalyst having high catalytic activity is adopted; furthermore, multi-batch indiscriminate use can be realized; and the method is high in yield, high in product purity, convenient to postprocess and environment friendly.

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Номер записи: 12
25-08-2010 дата публикации

Double-stage and four-feet matrix transformer based on generalized carrier modulation and its modulation

Номер: CN0101075786B
Автор: TAN HENGSI, GUI WEIHUA, LI MEI, SONG DONGRAN, HAN HAIPING, SUN YAO, WEI RENYONG, YANG CHUNHUA, HE JIANJUN, YU YUE, HENGSI TAN, WEIHUA GUI, MEI LI, DONGRAN SONG, HAIPING HAN, YAO SUN, RENYONG WEI, CHUNHUA YANG, JIANJUN HE, YUE YU
Принадлежит:

The invention newly adds a bridge arm on the inverse stage of currently-existed doublestage matrix convertor, and connects the point N in the newly-added bridge arm to the neutral point of load to generate a new topology; the inverse stage of doublestage matrix convertor provided by the invention has four pins. Based on the new topology structure, the invention also provides a carrier-based modulation policy having all advantages of both single and double stage matrix convertor and being capable of suppressing the output of zero sequence and meeting the requirement of symmetry and asymmetry load.

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Номер записи: 13
14-04-2023 дата публикации

Efficient synthesis method of cycloxaprid

Номер: CN115960118A
Автор: WANG TAO, HAN HAIPING, KONG QIANGUANG, BI QIANG, XU HAIYAN, ZHANG ZHIPING, FANG YAN
Принадлежит:

The invention discloses an efficient synthesis method of cycloxaprid, which comprises the following steps: step 1, adding a solvent, 2-chloro-5-((2-(nitromethylene) imidazoline-1-yl) methyl) pyridine, 2, 5-dichlorotetrahydrofuran and alkali into a reactor, controlling a certain temperature, and carrying out heat preservation reaction; and 2, after the reaction is finished, directly adding water, and filtering to obtain cycloxaprid. Compared with other reported methods, the method has the advantages that butanedialdehyde or 2, 5-dimethoxytetrahydrofuran is not used, 2, 5-dichlorotetrahydrofuran is directly adopted, the 2, 5-dichlorotetrahydrofuran can be obtained by directly introducing chlorine into relatively cheap tetrahydrofuran, and the cycloxaprid intermediate and the 2, 5-dichlorotetrahydrofuran are adopted, so that the cycloxaprid intermediate and the 2, 5-dichlorotetrahydrofuran are synthesized into the cycloxaprid intermediate, and the cycloxaprid intermediate and the 2, 5-dichlorotetrahydrofuran ...

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Номер записи: 14
12-05-2023 дата публикации

Synthesis method of prothioconazole intermediate hydrazino compound

Номер: CN116102452A
Автор: WANG TAO, HAN HAIPING, KONG QIANGUANG, BI QIANG, ZHANG ZHIPING
Принадлежит:

The invention provides a synthesis method of a prothioconazole intermediate hydrazino compound, which comprises the following steps: taking 2-(2-chlorobenzyl)-2-(1-chlorocyclopropyl) ethylene oxide as a raw material, and reacting with nearly equivalent hydrazine hydrate in the presence of a catalyst and a catalyst ligand to obtain the prothioconazole intermediate hydrazino compound. According to the process method, the using amount of hydrazine hydrate is greatly reduced, the cost of raw materials is reduced, meanwhile, the environmental protection pressure caused by excessive hydrazine hydrate is relieved, the reaction condition is mild, and the industrial application value is very high.

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Номер записи: 15