Big-skipping concentrate weir plate enabling user to easily disassemble and change

The invention discloses a big-skipping concentrate weir plate enabling a user to easily disassemble and change. The big-skipping concentrate weir plate comprises a stainless steel weir plate and a weir plate frame which are vertically arranged on jigger screen cloth, the weir plate frame is of a frame structure, the stainless steel weir plate is arranged on the lower portion of the weir plate frame and pressed on the upper surface of the screen cloth through the weir plate frame, and the big-skipping concentrate weir plate is a closing face from the upper end of the stainless steel weir plate to the upper surface of the screen cloth downwards. The big-skipping concentrate weir plate solves the technical problem that maintenance difficulty of a jigger is reduced. Service life of the weir plate is prolonged through the weir plate frame and the stainless steel weir plate fixedly arranged on the weir plate frame, maintenance difficulty of the weir plate is reduced, maintenance efficiency is ...

Method for crystallizing and producing cefpiramide sodium crystals

The invention discloses a method for crystallizing and producing cefpiramide sodium crystals. The method comprises the steps that: (a) cefpiramide acid and an transamination agent are dissolved in a solvent I, wherein the transamination agent is any one selected from triethylamine, diisopropylamine, and isopropylamine; and a temperature is controlled, and the materials are stirred until completely dissolved; (b) a salt-forming agent is added into a solvent II, wherein when the salt-forming agent is sodium ethylhexanoate, the solvent II is an acetone solvent, and when the salt-forming agent is sodium hydroxide, the solvent II is any one or a mixture of two selected from methanol and tetrahydrofuran; and the materials are stirred until completely dissolved; (c) the salt-forming agent solution is uniformly added into the solution of cefpiramide amine salt; the temperature is controlled, and crystal seeds are added; curing crystallization is carried out; acetone is added into the crystallization ...

Mango leaf extractive as well as preparation method and application thereof

The invention belongs to the field of traditional Chinese medicine and medicinal chemistry, relates to a mango leaf extractive as well as a preparation method and application thereof and particularly relates to a preparation method of the mango leaf extractive. The method comprises the following steps of: (1) extracting mango leaves by using an organic solvent to obtain an extracting solution; (2) concentrating the extracting solution in the step (1) and centrifuging the concentrated extracting solution to obtain a supernatant liquid; (3) eluting macroporous resin on the supernatant liquid in the step (2) to obtain an eluent; and (4) concentrating the eluent in the step (3) and drying the concentrated eluent to obtain a dry substance, namely the extractive. The invention also relates to the mango leaf extractive obtained by using the preparation method and an application of the mango leaf extractive to the preparation of medicaments for preventing and treating diabetes mellitus or hyperlipidemia ...

Abelmoschus manihot extract and novel application of chemical components thereof

The invention relates to an abelmoschus manihot extract and a novel application of chemical components thereof, concretely, relates to a compound of formula I or its pharmaceutically acceptable salt, solvate, ester and prodrug, and an extract containing the compound of formula I, a composition thereof and an application thereof. The compound or extract of the invention can be used as anti-oxidative damaging agent, and can be used for treating or preventing diseases or symptoms related to oxidative damage.

Medicinal composition for treating early-stage diabetic foot and preparation method thereof

The invention relates to a medicinal composition for treating an early-stage diabetic foot and a preparation method thereof. Particularly, the medicinal composition is prepared from medicinal materials serving as active components and optional pharmaceutically acceptable auxiliary materials, wherein the medicinal materials comprise tripterygium hypoglaucum, red peony root, radix angelicae pubescentis, angelica root and grassleaf sweelflag rhizome. The invention also relates to a gel prepared from the medical composition, application of the medicinal composition in preparation of a medical product for treating or preventing the diabetic foot, and the like. The medical composition can be used for treating the diabetic foot, such as early-stage diabetic foot.

New medicine application of traditional Chinese medicinal composition

The invention discloses a new medicine application of a traditional Chinese medicinal composition in preparing a medicine for treating vascular dementia. The traditional Chinese medicinal composition consists of the following crude medicines: 170-510 parts of uncaria rhynchophylla, 150-450 parts of ligusticum wallichii, 80-240 parts of ephedra, 80-240 parts of asarum, 80-240 parts of radix aconiti lateralis preparata, 100-300 parts of white paeony root, 80-240 parts of notopterygium root, 50-150 parts of radix angelicae pubescentis, 80-240 parts of divaricate saposhnikovia root, 80-240 parts of rehmannia, 80-240 parts of angelica, 250-750 parts of suberect spatholobus stem, 100-300 parts of peach kernel, 100-300 parts of safflower and 80-240 parts of radix angelicae. The traditional Chinese medicinal composition has a good effect on treating chronic cerebral hypoperfusion vascular dementia, multiple cerebal infarction vascular dementia and subcortical ischemic vascular dementia, and is ...

Application of tanshinone I to treatment of microglia-mediated disease

The invention relates to an application of tanshinone I shown in a formula I to the treatment of a microglia-mediated disease, in particular to an application of tanshinone I to the preparation of a medicament for treating and/or preventing the microglia-mediated disease, in particular to an application of tanshinone I to preparation of a medicament for treating and/or preventing psychoneuroimmunology chronic inflammatory diseases caused by microglia-mediated neurotoxic effects. The tanshinone I provided by the invention has the novel functions of remarkably suppressing microglia cell-activated and induced cell death, suppressing the generation and expression of inflammatory mediators, i.e., NO and TNF alpha of microglia cells, and remarkably lowering the cell toxicity of activated microglia cells on neurons, the tanshinone I can be applied to prevention and treatment of brain immune inflammation-related diseases such as Alzheimer's disease, Parkinson's disease, and the like. The formula ...

Door hinge

The invention discloses a door hinge designed by adopting a planar four-connecting rod mechanism and a group of correlated hinge point dimension data arrays. The door hinge comprises the planar four-connecting rod mechanism which is formed by connecting a fixed seat, a long oscillating rod, a movable seat, a short oscillating rod and a pin shaft, the door hinge is characterized in that the dimension G of an installation screw hole on the fixed seat is smaller than or equal to the dimension H of a hinge point on the long oscillating rod. A notch 18 is arranged on the long oscillating rod 2 to reduce the installation dimension of the door hinge, a supporting rib 19 is arranged on the fixed seat 1, and the supporting rib 19 props against the interior structure of the fixed seat 1 to improve the rigidity of the door hinge so as to well meet the requirements of utilization functions of an embedded refrigerator door hinge and the outline appearance design of the refrigerator.

Effective antibacterial traditional Chinese medicine composition

The invention relates to an effective antibacterial traditional Chinese medicine composition and in particular relates to a traditional Chinese medicine composition. The effective antibacterial traditional Chinese medicine composition includes radix sophorae flavescentis extract, green tea extract and perilla leaf extract as well as random pharmaceutically acceptable auxiliary materials. The invention further relates to a method for preparing the traditional Chinese medicine composition and application of the traditional Chinese medicine composition. Besides, the traditional Chinese medicine composition can be used for preventing microorganism (for example escherichia coli) infection.

Fructus crataegi leaf and novel application of extract of fructus crataegi leaf

The invention provides a fructus crataegi leaf and an application of an extract of the fructus crataegi leaf to preparation of a medicament for preventing and treating cataract. The fructus crataegi leaf and the extract thereof are used for increasing the oxidation resistance of an organism by inhibiting aldose reductase, so that the fructus crataegi leaf and the extract thereof can be used for preparing a medicament for preventing and treating cataract to fulfill the aim of treating cataract.

Compounds, extracting method thereof, pharmaceutical composition containing compounds and application of compounds and pharmaceutical composition

The invention provides compounds shown in a formula (I). In the formular (I), R2 is H and R3 is FORMULA 1 when R1 is FORMULA 2; or R2 is H and R3 is FORMULA 3 when R1 is FORMULA 4; or R2 is FORMULA 5 and R3 is FORMULA 6 when R1 is FORMULA 7, wherein '_' represents a connection position with matrix. The invention also provides an extracting method of the compounds shown in the formula (I), a pharmaceutical composition including the compounds, and application of the compounds and the pharmaceutical composition in preparation of a drug for preventing and/or treating diseases caused by dysfunction of mitochondria.

Application of isobavachalcone in treating nerve inflammatory diseases

The invention relates to application of isobavachalcone displayed in formula I in treating microglial cell mediated diseases, in particular to application of isobavachalcone in preparing medicines for treating and/or preventing microglial cell mediated diseases especially microglial cell mediated neural immune inflammatory diseases caused by neurotoxic effect. The isobavachalcone has new functions of being capable of obviously restraining microglial cellsfrom activating or inducing cells to die, restraining generation and expression of inflammatory media NO of activated microglial cells and obviously relieving cytotoxicity of activated microglial cells to neurons. Therefore, isobavachalcone can be applied to preventive treatment of diseases related to brain immune inflammatory diseases such as Parkinson's disease.

High-temperature solenoid valve and high-temperature thruster using same

The invention discloses a high-temperature solenoid valve and a high-temperature thruster using the same. A thermal insulation pipe is sleeved on the periphery of the part of a valve rod of the high-temperature solenoid valve extending from the lower portion of a solenoid valve casing, during usage, media can diffuse a large amount of heat when passing through inlets and outlets on a valve seat, while heat generated by high-temperature gas needs to be transmitted to an electromagnetism through the thermal insulation pipe and the valve base in a transmission, convection and radiation mode, and the thermal insulation pipe fixed between the electromagnetism and the valve base and the valve rod penetrating through the thermal insulation pipe are made of thermal insulation materials, so that the thermal bridge effect can be achieved, heat exchanging between the valve base and the electromagnetism is reduced, heat diffused to the electromagnetism from the valve base is reduced, temperature of ...

Traditional Chinese medicine composition with antibacterial function

The invention relates to a traditional Chinese medicine composition with antibacterial function. Specifically, the invention relates to a traditional Chinese medicine composition comprising a radix sophorae flavescentis extract, a green tea extract and optionally pharmaceutically acceptable excipients. The traditional Chinese medicine composition provided by the invention has good antibacterial effect.

Marble lock cylinder and lockset provided with the same

The invention provides a marble lock cylinder and a lockset provided with the same. Types of parts constituting the marble lock cylinder are reduced, processing is simple, and assembly is simple. Meanwhile, management is convenient, and safety of using areas is improved. The marble lock cylinder comprises a lock cylinder shell, a rotary core and more than one lock pin, wherein the rotary core is arranged inside the inner cavity of the lock cylinder through a transmission method. One end portion of the lock cylinder shell is provided with a key outlet, the rotary core comprises more than one lock pin installation hole, the lock pin is arranged inside the lock pin installation hole through a method that longitudinal reciprocating motion is convenient, a rotary core locking device is further arranged inside the inner cavity of the lock cylinder shell, and the rotary core locking device is arranged inside a transverse through hole of the side wall of the rotary core through a method that transverse ...

Application of genipin amino acid derivative as NF-kappa B inhibitor

The invention discloses application of a genipin amino acid derivative as an NF-kappa B (nuclear transcription factor kappa-B) inhibitor. The genipin amino acid derivative as the NF-kappa B inhibitor controls the expression of various inflammatory cytokines, major histocompatibility composite gene and adhesion molecules, which participate in the tumor metastasis, and restrains and treats pathological symptoms caused by NF-kappa B activation by blocking the nuclear factor NF-kappa B activation, wherein the symptoms include cancer, autoimmune diseases (such as rheumatoid arthritis), cardiovascnlar and cerebrovascular diseases, acute and chronic inflammations, nervous system disorders (depression, Alzheimer's disease, etc.). The genipin amino acid derivative can restrain the NF-kappa B activity in a dose and time-dependent manner. The invention provides a novel drug source for NF-kappa B inhibitors and NF-kappa B control related diseases.

Enterprise Security Management System Using Hierarchical Organization and Multiple Ownership Structure

A hierarchical security model for networked computer users is described. Files and resources are controlled or created by users within the network. Each user within the network has an account that is managed by a network administrator. The account specifies the user identifier and password. Users are grouped into organizations depending upon function or other organizational parameter. The groups within the network are organized hierarchically in terms of access and control privileges. Users within a higher level group may exercise access and control privileges over files or resources owned by users in a lower level group. The account for each user further specifies the group that the owner belongs to and an identifier for any higher level groups that have access privileges over the user's group. All users within a group inherit the rights and restrictions of the group. 1. A method comprising:assigning a first set of identifiers to a first set of users;assigning a second set of identifiers to each of the first set of users, the second set of identifiers associating a respective one of the first set of users with at least one of a second set of users where the at least one of the second set of users is granted permission to access one or more files associated with the respective one of the first set of users;receiving a request from a requestor among the second set of users to access a network resource associated with one of the first set of users;determining whether the requestor has permission to access the network resource;determining which privileges the requestor is given relative to the network resource if the requestor has permission to access the network resource; andproviding the requestor with the network resource based on the determined privilege.2. The method of claim 1 , wherein assigning the first identifier includes associating the first set of users with a plurality of child groups claim 1 , with at least two users in the first set of users being ...

ONLINE SYSTEM FOR FULFILLING LOAN APPLICATIONS FROM LOAN ORIGINATORS

A loan submission and processing system, methods, apparatus and computer program products. One example method includes receiving user specified input relating to a loan application, storing the user specified input in a loan application file, determining a partner system that is to receive data related to the electronic loan application including dynamically determining a format and contents required to present a service request to the partner system for processing by the partner system, dynamically formatting the user specified input and any other required content into a service request, the service request compatible with the partner system and including the user specified data and the other required content and transmitting the service request to the partner system. 1. A method for the formatting and transmission of data from a loan originator system to one or more partner systems , the method comprising:providing a loan origination software program including client and server portions, the client portion including an interface for receiving loan application data, the server portion including formatting and transmitting capability wherein the formatting and transmitting capability facilitates the entry of information into one or more loan forms associated with a target partner system;formatting including re-formatting and publishing loan application information provided by the loan origination software program in a format compatible with a financial service software program of a target partner system of the one or more partner systems; andtransmitting re-formatted loan application information to the target partner system.2. The method of wherein the target partner computers comprises at least one of the following claim 1 , a lender computer claim 1 , an underwriter company computer claim 1 , or a settlement service vendor computer.3. The method of further comprising validating the loan application information prior to transmission to the target partner system.4. ...

HUMIDIFIER

A humidifier includes a shell, a fixing bracket, an atomizer, and a control circuit assembly, and the fixing bracket is disposed in a containing cavity of the shell and divides the containing cavity into a first isolating cavity and a second isolating cavity opposite to each other; the control circuit assembly is disposed in the first isolating cavity, and a solution is contained in the second isolating cavity; the atomizer is positioned in the solution of the second isolating cavity and electrically connected to the control circuit assembly. The control circuit assembly controls the atomizer to atomize the solution. 1. A humidifier , comprising: a shell , a fixing bracket , an atomizer , and a control circuit assembly , wherein the shell has a containing cavity; the fixing bracket is disposed in the containing cavity , and the fixing bracket divides the containing cavity into a first isolating cavity and a second isolating cavity; the control circuit assembly is disposed in the first isolating cavity; the second isolating cavity is used for containing a solution; the atomizer is positioned in the second isolating cavity and is in contact with the solution , and the atomizer is electrically connected to the control circuit assembly.2. The humidifier according to claim 1 , wherein the shell comprises an end cover and a main housing claim 1 , the end cover is located at an upper portion of the main housing and forms the containing cavity with the main housing claim 1 , the end cover is detachably connected to the main housing; the fixing bracket is secured to the end cover.3. The humidifier according to claim 2 , wherein the fixing bracket comprises an isolating frame body fixed to the end cover claim 2 , the end cover and one side of the isolating frame body together form the first isolating cavity claim 2 , other sides of the isolating frame body and the main housing form the second isolating cavity; and the isolating frame body has a first opening for communicating ...

LOAN ORIGINATION SOFTWARE SYSTEM FOR PROCESSING MORTGAGE LOANS OVER A DISTRIBUTED NETWORK

A loan origination and processing system is described. The system can reside on a server computer that is coupled to a data store storing data related to a borrower. The server computer is further coupled to a brokerage network that comprises a loan officer client, a loan processor client, and a broker manager client. Each brokerage client computer executes a unique interface to the loan origination and processing system. 1. (canceled)2. A loan origination system comprising:a loan origination program;a database stored in a memory device coupled to a server computer, the database storing borrower data and loan data;a processing and management system configured to present a plurality of user interfaces corresponding to a plurality of user roles, each user interface being customized for presentation to a user based on a role of the user wherein users with different user roles are presented with different user interfaces, the user roles being selected from a group including an officer, a processor, or a manager;a milestone process defining one or more milestone events associated with processing each loan application and configured to evaluate progress of users associated with user roles as against the one or more milestone events; andan alert process defining one or more alert conditions associated with processing each loan application to achieve the one or more milestone events, wherein a respective user interface displays an alert graphical icon indicating an impending deadline upon triggering of an alert condition as a result of an imminent milestone that has yet to be completed.3. The system of further comprising a logging process logging milestone events associated with the loan application and logging communications between an officer client computer claim 2 , a processor client computer and a manager client computer.4. The system of wherein the logging process further logs communications among users of the system and document ordering and receiving status.5. The ...

ENTERPRISE SECURITY MANAGEMENT SYSTEM USING HIERARCHICAL ORGANIZATION AND MULTIPLE OWNERSHIP STRUCTURE

A hierarchical security model for networked computer users is described. Files and resources are controlled or created by users within the network. Each user within the network has an account that is managed by a network administrator. The account specifies the user identifier and password. Users are grouped into organizations depending upon function or other organizational parameter. The groups within the network are organized hierarchically in terms of access and control privileges. Users within a higher level group may exercise access and control privileges over files or resources owned by users in a lower level group. The account for each user further specifies the group that the owner belongs to and an identifier for any higher level groups that have access privileges over the user's group. All users within a group inherit the rights and restrictions of the group. 1. A method comprising:identifying an administrator that has access rights and permissions to all network resources in a set of network resources and a plurality of different groups of users including at least one parent group having at least one child group, wherein access rights and permissions are established for each group and wherein parent groups inherit access rights and permissions for their respective child groups;for a user in either the at least one parent group or the at least one child group, associating one or more network resources in the set of network resources with the user;assigning a set of identifiers to the user, the set of identifiers associating the user with at least one of a second set of users wherein the at least one of the second set of users is granted permission to access the one or more network resources associated with the user, wherein the at least one of the second set of users is not the administrator and not in the at least one parent group or at least one child group or any other group associated with the user and wherein the assigning of the set of identifiers ...

Composition of a VEGF antagonist and an anti-proliferative agent and its use for the treatment of cancer

Composition of a vegf antagonist and an anti-proliferative agent

Methods of treating cancer and/or reducing or inhibiting tumor growth in a subject in need thereof, comprising administering pharmaceutical composition comprising a vascular endothelial cell growth factor (VEGF) antagonist, such as a VEGF trap, an anti-proliferative agent, such as taxol, and a pharmaceutically acceptable carrier.

Automatic web-based client-server application program update system

An automated software update method for distributed client/server computers is described. A server process is executed a program on either a standalone computer or a server computer in a distributed client/server network environment. The program updates are either programmed into the server process directly or downloaded to the server in the background. When there is an update to the program, the server forces all client computers executing client-side processes of the server process to shutdown the client process. Alternatively, the server process notifies all clients that an update or maintenance procedure needs to be performed and schedules a disconnect request for all clients. When all clients are disconnected, the server downloads the program updates and performs an automated process to update itself. After the server program is updated, the server allows reconnection of the client computers. When a client computer connects to this server, a client process will automatically perform the update of the client program. This mechanism ensures that all clients and the server will be synchronized with respect to the version of their respective client/server program modules.

Humidifier

A humidifier includes a shell, a fixing bracket, an atomizer, and a control circuit assembly, and the fixing bracket is disposed in a containing cavity of the shell and divides the containing cavity into a first isolating cavity and a second isolating cavity opposite to each other; the control circuit assembly is disposed in the first isolating cavity, and a solution is contained in the second isolating cavity; the atomizer is positioned in the solution of the second isolating cavity and electrically connected to the control circuit assembly. The control circuit assembly controls the atomizer to atomize the solution.

Composition of a VEGF antagonist and an anti-proliferative agent and its use for the treatment of cancer

Loan origination software system for processing mortgage loans over a distributed network

A loan origination and processing system is described. The system can reside on a server computer that is coupled to a data store storing data related to a borrower. The server computer is further coupled to a brokerage network that comprises a loan officer client, a loan processor client, and a broker manager client. Each brokerage client computer executes a unique interface to the loan origination and processing system.

COMPOSITION OF A VEGF ANTAGONIST AND AN ANTIPROLIFERATIVE AGENT

Métodos para tratar al cáncer y/o reducir o inhibir el crecimiento tumoral en un sujeto con dicha necesidad, que comprenda el administrar un composición farmacéutica comprendiendo un antagonista de factor de crecimiento de células del endotelio vascular (VEGF), tal como una trampa de VEGF, y un agente antiproliferativo, tal como taxol, y un portador farmacéuticamente aceptable. Methods for treating cancer and / or reducing or inhibiting tumor growth in a subject with said need, comprising administering a pharmaceutical composition comprising a vascular endothelial cell growth factor antagonist (VEGF), such as a VEGF trap , and an antiproliferative agent, such as taxol, and a pharmaceutically acceptable carrier.

Composition of a vegf antagonist and an anti-proliferative agent

Methods of treating cancer and/or reducing or inhibiting tumor growth in a subject in need thereof, comprising administering pharmaceutical composition comprising a vascular endothelial cell growth factor (VEGF) antagonist, such as a VEGF trap, an anti-proliferative agent, such as taxol, and a pharmaceutically acceptable carrier.

Loan origination system interface for online loan application processing

A loan origination system interface module, methods and computer program products. One computer program product for processing loan application data including instructions to extract loan application data including retrieving identification information for a loan application associated the loan application data from a broker device and displaying on the broker device a list of loan applications available to process in an interface that is consistent with a loan origination computer program associated with the broker device. In response to command input from the broker device selecting a loan application from the list of loan applications, the computer program product includes instructions to reformat loan application data for the selected loan application to a format compatible with that required by a lender device and transmit reformatted loan application data to a lender device.