28-07-2023 дата публикации
Номер: CN116500158A
Принадлежит:
The invention provides a blood sample antiepileptic drug detection method and a kit, and relates to the technical field of drug detection. The anti-epileptic drugs detected by the detection method comprise carbamazepine, epoxy carbamazepine, oxcarbazepine, 10, 11-dihydro-10-hydroxy carbamazepine, phenytoin sodium, lamotrigine, levetiracetam, pregabalin, gabapentin, topiramate, valproic acid, phenobarbital and lacosamide. The detection method comprises the following steps: detecting a pretreated to-be-detected sample by using high performance liquid chromatography-tandem mass spectrometry, substituting a detection value into a standard curve, and calculating to obtain the content of the anti-epileptic drugs in the blood sample, the pretreatment comprises the step of treating a to-be-detected sample by adopting a precipitant, the precipitant contains an internal standard, and the internal standard is an isotope of an anti-epileptic drug. The detection method has the advantages of rapidness ...
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