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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 17. Отображено 16.
07-11-2013 дата публикации

MATRIX METALLOPROTEINASE INHIBITORS

Номер: US20130295141A1
Автор: DASTIDAR Sunanda G., JOSEPH Sony, KHERA Manoj Kumar, MUSIB Arpita, PALLE Venkata P., RAUF Abdul Rehman Abdul, REDDY Ranadheer, SATTIGERI Viswajanani J., Soni Ajay, SRIVASTAVA Punit Kumar, TIWARI Manoj Kumar
Принадлежит:

The present invention relates to β-hydroxy and amino-substituted carboxylic acids, which act as matrix metalloproteinase inhibitors, particularly diastereomerically pure β-hydroxy carboxylic acids, corresponding processes for their synthesis, and pharmaceutical compositions containing the compounds of the present invention. Compounds of the present invention are useful in the treatment of various inflammatory, autoimmune, and allergic diseases, such as methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis, wound healing disorders, pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple sclerosis, gingivitis, atherosclerosis, neointimal proliferation, which leads to restenosis and ischemic heart failure, stroke, renal diseases, tumor metastasis, and other inflammatory disorders characterized by the over-expression and over-activation of a matrix metalloproteinase. 2. A compound which is selected from:(2S,3R)-2-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]-5-[6-(3-fluoro-4-methoxyphenyl)pyridin-3-yl]-3-hydroxypentanoic acid (Compound No. 55);(2S,3R)-2-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]-3-hydroxy-5-[6-(4-methoxyphenyl)pyridin-3-yl]pentanoic acid (Compound No. 57);(2S,3R)-5-[6-(4-chlorophenyl)pyridin-3-yl]-2-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]-3-hydroxypentanoic acid (Compound No. 59);(2S,3R)-2-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]-3-hydroxy-5-(6′-methoxy-2,3′-bipyridin-5-yl)pentanoic acid (Compound No. 60);(2S,3R)-5-[4-(4-chlorophenyl)-2-thienyl]-2-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]-3-hydroxypentanoic acid (Compound No. 61);(2S,3R)-2-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]-3-hydroxy-5-[4-(6-methoxypyridin-3-yl)-2-thienyl]pentanoic acid (Compound No. 62);(2S,3R)-2-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]-3-hydroxy-5-{4-[4-(trifluoromethyl)phenyl]-2-thienyl}pentanoic acid (Compound No. 63 ...

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Номер записи: 1
14-11-2013 дата публикации

MATRIX METALLOPROTEINASE INHIBITORS

Номер: US20130302378A1
Автор: DASTIDAR Sunanda G., JOSEPH Sony, KHERA Manoj Kumar, MUSIB Arpita, PALLE Venkata P., RAUF Abdul Rehman Abdul, REDDY Ranadheer, SATTIGERI Viswajanani J., Soni Ajay, SRIVASTAVA Punit Kumar, TIWARI Manoj Kumar
Принадлежит:

The present invention relates to β-hydroxy and amino-substituted carboxylic acids, which act as matrix metalloproteinase inhibitors, particularly diastereomerically pure β-hydroxy carboxylic acids, corresponding processes for their synthesis, and pharmaceutical compositions containing the compounds of the present invention. Compounds of the present invention are useful in the treatment of various inflammatory, autoimmune, and allergic diseases, such as methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis, wound healing disorders, pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple sclerosis, gingivitis, atherosclerosis, neointimal proliferation, which leads to restenosis and ischemic heart failure, stroke, renal diseases, tumor metastasis, and other inflammatory disorders characterized by the over-expression and over-activation of a matrix metalloproteinase. 2. A compound which is selected from:(2S,3R)-5-(3,3′-difluoro-4′-methoxybiphenyl-4-yl)-2-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]-3-hydroxypentanoic acid (Compound No. 47);(2S,3R)-2-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]-5-[2-fluoro-4-(6-methoxypyridin-3-yl)phenyl]-3-hydroxypentanoic acid (Compound No. 50);(2S,3R)-5-(4′-chloro-3-fluorobiphenyl-4-yl)-2-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]-3-hydroxypentanoic acid (Compound No. 56);(2S,3R)-2-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]-5-β-fluoro-4′-methoxybiphenyl-4-yl)-3-hydroxypentanoic acid (Compound No. 58);(2S,3R)-5-[2-fluoro-4-(6-methoxypyridin-3-yl)phenyl]-3-hydroxy-2-[2-(4-oxo-1,2,3-benzotriazin-3(4H)-yl)ethyl]pentanoic acid (Compound No. 153);(2S,3R)-5-[2-fluoro-4-(6-methoxypyridin-3-yl)phenyl]-3-hydroxy-2-[2-(7-methoxy-4-oxo-1,2,3-benzotriazin-3(4H)-yl)ethyl]pentanoic acid (Compound No. 154);(2S,3R)-5-[2-fluoro-4-(6-methoxypyridin-3-yl)phenyl]-2-[2-(5-fluoro-4-oxo-1,2,3-benzotriazin-3(4H)-yl)ethyl]-3- ...

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Номер записи: 2
27-03-2014 дата публикации

USING FINANCIAL TRANSACTIONS TO GENERATE RECOMMENDATIONS

Номер: US20140089136A1
Автор: JOSEPH Sony, Mukherjee Saikat
Принадлежит:

The disclosed embodiments provide a system that processes transaction data. During operation, the system obtains the transaction data for a set of financial transactions between a set of users and a set of organizations. Next, the system uses the transaction data to calculate a set of preference scores for the users and the organizations. Finally, the system generates recommendations associated with the users and the organizations from the preference scores without obtaining explicit preferences for the organizations from the users. 1. A computer-implemented method for processing transaction data , comprising:obtaining the transaction data for a set of financial transactions between a set of users and a set of organizations;using the transaction data to calculate a set of preference scores for the users and the organizations; andgenerating recommendations associated with the users and the organizations from the preference scores without obtaining explicit preferences for the organizations from the users.2. The computer-implemented method of claim 1 , further comprising:updating the transaction data with new financial transactions between the users and the organizations; andupdating the preference scores based on the updated transaction data.3. The computer-implemented method of claim 1 , wherein using the transaction data to calculate the set of preference scores for the users and the organizations involves:calculating a preference score for each user from the set of users and each organization from the set of organizations.4. The computer-implemented method of claim 3 , wherein the preference score comprises at least one of:an inverse document frequency score;a spending score; anda visit score.5. The computer-implemented method of claim 4 , wherein the spending score is at least one of:a first spending score for the user normalized across the set of users; anda second spending score for the user normalized across the set of organizations.6. The computer-implemented ...

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Номер записи: 3
19-11-2015 дата публикации

Ranking autocomplete results based on a business cohort

Номер: US20150331878A1
Автор: Ilya A. Izrailevsky, Sony Joseph, Sunil K. Tripathy
Принадлежит: Intuit Inc

During this autocomplete technique, autocomplete results for data-entry information from a user are ranked based on financial-transaction histories of a group of entities and the user, where the group of entities and the user belong to a common business cohort. In particular, the business cohort may include entities that: are located proximate to the user, have a similar size as a business associated with the user (such as a similar number of employees and/or similar revenue), and/or occur frequently in a financial-transaction history of the user (and don't occur frequently in the financial-transaction histories of the group of entities). The ranking may be used to increase the accuracy or relevance of the autocomplete results to the user. For example, the ranking may give preference in the autocomplete results to entities in the group of entities (relative to other entities, such as those in different business cohorts).

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Номер записи: 4
09-11-2017 дата публикации

Distributed Data Access Control

Номер: US20170322992A1
Автор: Heller Jonathan, JOSEPH Sony
Принадлежит:

Systems for distributed controlled access to data stored across a plurality of sources are disclosed. A plurality of content providers maintain user databases. A first distributed database contains a master identifier for each user of each content provider. Stored in relation to the master identifier are the locations of the user's data in each of the content providers. A second distributed database comprises data identifying for each of the users, entities that are authorized to access the user's data. In response to a request from an entity, the second database is queried and, based upon access rights data, user's whose data the requesting entity may view are determined. The first distributed database is queried to determine for the identified user, the location of user data. The data is retrieved and stored at a location accessible by the entity. The second distributed database is updated to record the data access. 1. A method comprising:maintaining user data for each of a plurality of content provider systems, the user data comprising, for each of a plurality of users, data identifying user characteristics;maintaining a first distributed database, the first distributed database comprising for each of a plurality of users, a master public key and at least one data storage location on one of the content provider systems;maintaining a second distributed database, the second distributed database comprising, for each of a plurality of entities, data identifying users whose data is available to be accessed, and data recording accesses of user data by entities; and querying the second distributed database to determine users whose data is accessible to the requesting entity;', 'querying the first distributed database to determine, for each of the determined users whose data is accessible to the requesting entity, one or more storage locations on the plurality of content provider systems;', 'retrieving data from the determined one or more storage locations on the ...

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Номер записи: 5
03-01-2001 дата публикации

Method for reducing noise in an input speech signal

Номер: EP1065656A2
Автор: Joseph Sony Corporation Chan, Masayuki Sony Corporation Nishiguchi
Принадлежит: Sony Corp

A method for reducing the noise in an input speech signal in which noise suppression is done by adaptively controlling a maximum likelihood filter adapted for calculating speech components based on the probability of speech occurrence and the S/N ratio calculated based on the input speech signal,    characterised by the characteristics of the maximum likelihood filter being smoothing filtered along the frequency axis and along the time axis.

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Номер записи: 6
13-11-2015 дата публикации

Ranking autocomplete results based on a business cohort

Номер: CA2892830A1
Автор: Ilya A. Izrailevsky, Sony Joseph, Sunil K. Tripathy
Принадлежит: Intuit Inc

During this autocomplete technique, autocomplete results for data-entry information from a user are ranked based on financial-transaction histories of a group of entities and the user, where the group of entities and the user belong to a common business cohort. In particular, the business cohort may include entities that: are located proximate to the user, have a similar size as a business associated with the user (such as a similar number of employees and/or similar revenue), and/or occur frequently in a financial-transaction history of the user (and don't occur frequently in the financial-transaction histories of the goup of entities). The ranking may be used to increase the accuracy or relevance of the autocomplete results to the user. For example, the ranking may give preference in the autocomplete results to entities in the group of entities (relative to other entities, such as those in different business cohorts).

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Номер записи: 7
01-03-1995 дата публикации

Voiced-unvoiced discrimination method

Номер: EP0640952A2
Автор: Joseph C/O Sony Corporation Chan, Jun C/O Sony Corporation Matsumoto, Masayuki C/O Sony Corporation Nishiguchi
Принадлежит: Sony Corp

There is provided a speech efficient coding method applicable to, e.g., analysis by synthesis system such as MBE vocoder, and comprising the steps of: dividing an input speech signal in block units on the time base; dividing signals every respective divided blocks into signals in a plurality of frequency bands; discriminating whether signals every respective divided frequency bands are voiced sound (V) or unvoiced sound (UV); and reflecting each discrimination result of voiced sound/unvoiced sound of a frequency band on a lower frequency side in discrimination of voiced sound/unvoiced sound of a frequency band on a higher frequency side to obtain an ultimate discrimination result of voiced sound/unvoiced sound. Thus, even in the case where pitch suddenly changes, or harmonics structure is not precisely in correspondence with multiple of integer of the fundamental pitch period, stable judgement of V (Voiced Sound) can be made.

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Номер записи: 8
19-10-2021 дата публикации

Ranking autocomplete results based on a business cohort

Номер: CA2892830C
Автор: Ilya A. Izrailevsky, Sony Joseph, Sunil K. Tripathy
Принадлежит: Intuit Inc

During this autocomplete technique, autocomplete results for data-entry information from a user are ranked based on financial-transaction histories of a group of entities and the user, where the group of entities and the user belong to a common business cohort. In particular, the business cohort may include entities that: are located proximate to the user, have a similar size as a business associated with the user (such as a similar number of employees and/or similar revenue), and/or occur frequently in a financial-transaction history of the user (and don't occur frequently in the financial-transaction histories of the goup of entities). The ranking may be used to increase the accuracy or relevance of the autocomplete results to the user. For example, the ranking may give preference in the autocomplete results to entities in the group of entities (relative to other entities, such as those in different business cohorts).

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Номер записи: 9
16-11-2017 дата публикации

Distributed data access control

Номер: CA3023831A1
Автор: Jonathan Heller, Sony Joseph
Принадлежит: COMCAST CABLE COMMUNICATIONS LLC

Systems for distributed controlled access to data stored across a plurality of sources are disclosed. A plurality of content providers maintain user databases. A first distributed database contains a master identifier for each user of each content provider. Stored in relation to the master identifier are the locations of the user's data in each of the content providers. A second distributed database comprises data identifying for each of the users, entities that are authorized to access the user's data. In response to a request from an entity, the second database is queried and, based upon access rights data, user's whose data the requesting entity may view are determined. The first distributed database is queried to determine for the identified user, the location of user data. The data is retrieved and stored at a location accessible by the entity. The second distributed database is updated to record the data access.

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Номер записи: 10
18-05-2011 дата публикации

Matrix metalloproteinase inhibitors

Номер: EP2322507A1
Автор: Abdul Rehman Abdul Rauf, Ajay Soni, Arpita Musib, Manoj Kumar Khera, Manoj Kumar Tiwari, Punit Kumar Srivastava, Ranadheer Reddy, Sony Joseph, Sunanda G. Dastidar, Venkata P. Palle, Viswajanani J. Sattigeri
Принадлежит: Ranbaxy Laboratories Ltd

The present invention relates to β-hydroxy and amino substituted carboxylic acids, which act as matrix metalloprotease inhibitors, particularly diastereomerically pure β-hydroxy carboxylic acids, corresponding processes for the synthesis of and pharmaceutical compositions containing the compounds of the present invention. Compounds of the present invention are useful in the treatment of various inflammatory, autoimmune and allergic diseases, such as methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis, wound healing disorders, pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple sclerosis, gingivitis, atherosclerosis, neointimal proliferation, which leads to restenosis and ischemic heart failure, stroke, renal diseases, tumor metastasis, and other inflammatory disorders characterized by the over-expression and over-activation of a matrix metalloproteinase using the compounds.

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Номер записи: 11
28-02-2008 дата публикации

Matrix metalloproteinase inhibitors

Номер: WO2008023336A2
Автор: Abdul Rehman Abdul Rauf, Ajay Soni, Arpita Musib, Manoj Kumar Khera, Manoj Kumar Tiwari, Punit Kumar Srivastava, Ranadheer Reddy, Sony Joseph, Sunanda G. Dastidar, Venkata P. Palle, Viswajanani J. Sattigeri
Принадлежит: RANBAXY LABORATORIES LIMITED

The present invention relates to β-hydroxy and amino substituted carboxylic acids, which act as matrix metalloprotease inhibitors, particularly diastereomerically pure β-hydroxy carboxylic acids, corresponding processes for the synthesis of and pharmaceutical compositions containing the compounds of the present invention. Compounds of the present invention are useful in the treatment of various inflammatory, autoimmune and allergic diseases, such as methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis, wound healing disorders, pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple sclerosis, gingivitis, atherosclerosis, neointimal proliferation, which leads to restenosis and ischemic heart failure, stroke, renal diseases, tumor metastasis, and other inflammatory disorders characterized by the over-expression and over- activation of a matrix metalloproteinase using the compounds.

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Номер записи: 12
20-01-2016 дата публикации

Ranking autocomplete results based on a business cohort

Номер: EP2973270A1
Автор: Ilya A. Izrailevsky, Sony Joseph, Sunil K. Tripathy
Принадлежит: Intuit Inc

During this autocomplete technique, autocomplete results for data-entry information from a user are ranked based on financial-transaction histories of a group of entities and the user, where the group of entities and the user belong to a common business cohort. In particular, the business cohort may include entities that: are located proximate to the user, have a similar size as a business associated with the user (such as a similar number of employees and/or similar revenue), and/or occur frequently in a financial-transaction history of the user (and don't occur frequently in the financial-transaction histories of the group of entities). The ranking may be used to increase the accuracy or relevance of the autocomplete results to the user. For example, the ranking may give preference in the autocomplete results to entities in the group of entities.

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Номер записи: 13
19-09-2023 дата публикации

Distributed data access control

Номер: CA3023831C
Автор: Jonathan Heller, Sony Joseph
Принадлежит: COMCAST CABLE COMMUNICATIONS LLC

Systems for distributed controlled access to data stored across a plurality of sources are disclosed. A plurality of content providers maintain user databases. A first distributed database contains a master identifier for each user of each content provider. Stored in relation to the master identifier are the locations of the user's data in each of the content providers. A second distributed database comprises data identifying for each of the users, entities that are authorized to access the user's data. In response to a request from an entity, the second database is queried and, based upon access rights data, user's whose data the requesting entity may view are determined. The first distributed database is queried to determine for the identified user, the location of user data. The data is retrieved and stored at a location accessible by the entity. The second distributed database is updated to record the data access.

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Номер записи: 14
28-11-2017 дата публикации

Determining a likelihood that two entities are the same

Номер: US09830325B1
Автор: Ilya A. Izrailevsky, Sony Joseph, Sunil K. Tripathy
Принадлежит: Intuit Inc

The disclosed embodiments provide a system that determines a likelihood that a first entity and a second entity are the same entity. During operation, the system obtains financial data related to the first entity and obtains financial data related to the second entity. Next, the system determines the likelihood that the first entity and the second entity are the same entity based on the relationship between the financial data for the first entity and the financial data for the second entity. Then, the system alters a record related to the first entity or the second entity based on the likelihood.

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Номер записи: 15
10-01-2017 дата публикации

Categorizing financial transactions based on business preferences

Номер: US09542710B1
Автор: Ilya A. Izrailevsky, Sony Joseph
Принадлежит: Intuit Inc

During operation of a system, a financial transaction of an individual is associated with one or more predefined categories based on scores that indicate the likelihood of association. For example, a given predefined category may include a merchant name (such as the name of a potential counterparty in the financial transaction) and/or an attribute associated with one or more merchants. The score for a given predefined category may be determined based on financial-transaction preferences of the individual, where the financial-transaction preferences are specified by financial transactions in a financial-transaction history of the individual. The financial-transaction preferences may include a business-size preference (such as local versus national chains) and/or predefined categories in the financial-transaction history.

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Номер записи: 16