03-01-2019 дата публикации
Номер: US20190002609A1
Принадлежит:
A polymeric compound is disclosed herein, having the general formula I: 2. The polymeric compound of claim 1 , wherein Y is a substituted or unsubstituted alkylene unit.3. (canceled)4. The polymeric compound of claim 2 , wherein Y has the formula —CRR—CRD- claim 2 , wherein:{'sub': '7', 'when Y is a backbone unit which is not attached to said L or said Z, D is R; and when Y is a backbone unit which is attached to said L or said Z, D is a covalent bond or a linking group attaching Y to said L or said Z, said linking group being selected from the group consisting of —O—, —S—, alkylene, arylene, sulfinyl, sulfonyl, phosphate, phosphonyl, phosphinyl, carbonyl, thiocarbonyl, urea, thiourea, O-carbamyl, N-carbamyl, O-thiocarbamyl, N-thiocarbamyl, C-amido, N-amido, C-carboxy, O-carboxy, sulfonamido, and amino; and'}{'sub': 4', '7, 'R-Rare each independently selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heteroaryl, heteroalicyclic, halo, hydroxy, alkoxy, aryloxy, thiohydroxy, thioalkoxy, thioaryloxy, sulfinyl, sulfonyl, cyano, nitro, azide, azo, phosphate, phosphonyl, phosphinyl, oxo, carbonyl, thiocarbonyl, urea, thiourea, O-carbamyl, N-carbamyl, O-thiocarbamyl, N-thiocarbamyl, C-amido, N-amido, C-carboxy, O-carboxy, sulfonamido, and amino.'}511-. (canceled)12. The polymeric compound of claim 1 , wherein A is a substituted or unsubstituted hydrocarbon from 1 to 4 carbon atoms in length.1315-. (canceled)16. The polymeric compound of claim 1 , wherein n is at least 3.17. (canceled)18. The polymeric compound of claim 1 , wherein at least a portion of said Y claim 1 , said L and/or said Z comprise at least one targeting moiety.19. (canceled)20. The polymeric compound of claim 1 , wherein said lipid is selected from the group consisting of a fatty acid claim 1 , a monoglyceride claim 1 , a diglyceride claim 1 , a triglyceride claim 1 , a glycerophospholipid claim 1 , a sphingolipid claim 1 , and a sterol.21. (canceled)2327-. ( ...
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