24-11-2022 дата публикации
Номер: US20220372665A1
Автор:
Amanda Baryshyan,
Nick Zhang,
Jesse Groner,
Adam Behrens,
Nicole Marco,
Samantha Roman,
Rebeca Lopez-Garcia,
Lindsay Perrea,
Colin Preston,
Laith Abu-Taleb,
Linda Michelle Rauch,
Herve Irenee Garant, III,
John Patrick Ellersick
Принадлежит:
The disclosure relates to systems and methods for improving the manufacturing of silk solutions and powders containing silk fibroin obtained from silkworm cocoons. The solutions and powders can be used to improve the post-harvest preservation of perishables and to improve the performance of packaging, including biodegradable packaging. 1. A method of processing silk inputs to obtain food grade silk fibroin , the method comprising the steps of:introducing a plurality of silk inputs to a single reactor vessel;introducing a solvent to the single reactor vessel;introducing a first compound to the single reactor vessel;introducing heat to the single reactor vessel contents to promote degumming of the silk inputs;controlling movement or positioning of the silk inputs within the single reactor vessel;removing at least a portion of the solvent and any degumming residue from the single reactor vessel;rinsing the degummed silk inputs;introducing a second compound to the single reactor vessel to dissolve any remaining silk fibroin proteins into solution;agitating the contents of the single reactor vessel;filtering the contents of the single reactor vessel to substantially remove the second compound and produce a purified silk fibroin-based solution; andpowderizing the purified silk fibroin-based solution to obtain the purified silk fibroin in a powder form.2. The method of claim 1 , wherein the silk inputs come from a Bombyx mori silkworm.3. The method of claim 1 , wherein a packing density of the silk inputs in the single reactor vessel is between about 1% and about 70%.4. The method of claim 1 , wherein a packing density of the silk inputs in the single reactor vessel is greater than 5%.5. The method of claim 1 , wherein a packing density of the silk inputs in the single reactor vessel is greater than 15%.6. The method of claim 1 , wherein a packing density of the silk inputs in the single reactor vessel is greater than 25%.7. The method of claim 1 , wherein the filtering ...
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