Schreiben neuer Daten einer ersten Blockgröße in einen RAID-Array, der sowohl die Parität als auch die Daten in einer zweiten Blockgröße speichert

Verfahren implementiert in einer Vorrichtung, wobei das Verfahren umfasst:Empfangen neuer Daten, durch einen „Redundante Anordnung unabhängiger Platten“ (RAID)-Controller (102), die geschrieben werden sollen, wobei die neuen Daten in Blöcken einer ersten Blockgröße angegeben werden;Lesen alter Daten (606) und alter Parität (608) durch den RAID-Controller (102), die den alten Daten entspricht, gespeichert in Blöcken einer zweiten Blockgröße, die größer ist als die erste Blockgröße;Berechnen einer neuen Parität (610) durch den RAID-Controller (102), basierend auf den neuen Daten, den alten Daten, und der alten Parität; undSchreiben der neuen Daten und der neuen Parität durch den RAID-Controller (102), ausgerichtet auf die Blöcke der zweiten Blockgröße, wobei Teile der alten Daten, die nicht durch den RAID-Controller (102) überschrieben werden, ebenfalls in die Blöcke der zweiten Blockgröße geschrieben werden, wobei der RAID-Controller (102) Platten steuert, die als RAID-5 konfiguriert sind ...

PositIonieren elnes Grobaktors eines Bandservosystems mit zusammengesetztem Aktor am MIttelpunkt maximaler Höchstwerte seitlicher Bandbewegung

Wenn ein Band seitlichen Verschiebungsauslenkungen von einer Seite eines Kopfes zur anderen unterworfen ist, wird ein Grobaktor seitlich positioniert, um es einem Feinaktor zu ermöglichen, der seitlichen Bewegung eines längslaufenden Bandes mit mindestens einer festgelegten Servospur zu folgen. Eine Positionsfehlersignalschleife ist so eingerichtet, dass sie einen oder mehrere Servosensoren erfassen kann und einen Positionsfehler zwischen dem Kopf und einer gewünschten Position bezüglich der festgelegten Servospur(en) bestimmen kann. Eine Servosteuerung erfasst die seitliche Verschiebungsauslenkung der festgelegten Servospur(en); bestimmt einen maximalen positiven Höchstwert und einen maximalen negativen Höchstwert der seitlichen Verschiebungsauslenkung; und positioniert den Grobaktor im Wesentlichen an einem Mittelpunkt des maximalen positiven Höchstwertes und des maximalen negativen Höchstwertes der seitliche Verschiebungsauslenkung der festgelegten Servospur(en). Somit folgt der Feinaktor ...

Erkennung und Erfassung eines Servomusters

Ein Verfahren, ein Servosystem und ein Bandlaufwerk zum Erreichen eines Einrastens auf ein Servosignal werden bereitgestellt. Die Servosignale mindestens eines Servoelements werden überwacht, um ein gültiges Servosignal zu erkennen. Wird kein gültiges Servosignal erkannt, wird der Fein-Aktor in eine erste Richtung bewegt, bis entweder ein gültiges Servosignal erkannt wird oder die Grenze des Verfahrweges des Fein-Aktors erreicht wird. Wird ein gültiges Servosignal erkannt, wird der Fein-Aktor auf die Nulllage gesetzt und der Grob-Aktor in die erste Richtung bewegt. Wird die Grenze des Verfahrweges des Fein-Aktors erreicht, wird der Fein-Aktor zur ersten Position bewegt und der Grob-Aktor in eine zweite, der ersten Richtung entgegengesetzte Richtung bewegt.

Schräglauf-Stellglied zum Spurnachführen auf den Nullbezug

Servoerkennungssystem zum Erkennen von Servospuren eines Längsbands. In einem Lese-/Schreibkopf sind zwei Servoleseköpfe in einem seitlichen Abstand auf einem ersten Kopfmodul angeordnet, und ein Servolesekopf ist auf einem zweiten Kopfmodul in einem Längsabstand von dem ersten Modul angeordnet. Ein Verfahren umfasst anfangs das Erkennen einer Bandservospur mit einem Servolesekopf eines ersten Moduls und dem Servolesekopf des zweiten Moduls zum Ermitteln der Schräglauf-Fehlausrichtung der Servospur. Ein der Schräglauf-Fehlausrichtung entsprechender Nullbezugswert wird gespeichert. Das Erkennungssystem schaltet von dem einen Servolesekopf jedes Moduls auf die zwei Servoleseköpfe des ersten Moduls um und verwendet den gespeicherten Wert, um den Lese-/Schreibkopf in der Position mit Null-Schräglauf zu positionieren. Die zwei Servoleseköpfe werden dann verwendet, um zwei Servospuren zu lesen, um das Datenband zu identifizieren und den Schräglauf zu steuern.

Positionieren eines Grobaktors eines Bandservosystems mit zusammengesetztem Aktor am Mittelpunkt maximaler Höchstwerte seitlicher Bandbewegung

Variabler Schreibstopp-Schwellenwert mit variablem Glättungsfaktor

Datenspeichersystem (100), aufweisend: einen Kopf (126); einen Antriebsmechanismus zum Führen eines Mediums (122) über den Kopf (126); eine elektrisch mit dem Kopf (126) verbundene Steuereinheit (128); in die Steuereinheit (128) codierte oder dieser zur Verfügung stehende Logik zum periodischen Ermitteln eines Schreibstopp-Schwellenwerts auf der Grundlage einer aktuellen Standardabweichung oder einer aktuellen Varianz von Positionsfehlersignalabtastwerten, eines momentanen Positionsfehlersignal-Abtastwerts und eines Glättungsfaktors, wobei der Glättungsfaktor, der auf eine nachfolgende Berechnung der Standardabweichung oder Varianz angewendet wird, zumindest teilweise auf der Grundlage einer momentanen Größe der Standardabweichung oder der Varianz verändert wird; in die Steuereinheit (128) codierte oder dieser zur Verfügung stehende Logik zum Ermitteln, ob der momentane Positionsfehlersignal-Abtastwert den Schreibstopp-Schwellenwert überschreitet; in die Steuereinheit (128) codierte oder ...

Positionieren eines Grobaktors eines Bandservosystems mit zusammengesetztem Aktor am Mittelpunkt maximaler Höchstwerte seitlicher Bandbewegung

Wenn ein Band seitlichen Verschiebungsauslenkungen von einer Seite eines Kopfes zur anderen unterworfen ist, wird ein Grobaktor seitlich positioniert, um es einem Feinaktor zu ermöglichen, der seitlichen Bewegung eines längslaufenden Bandes mit mindestens einer festgelegten Servospur zu folgen. Eine Positionsfehlersignalschleife ist so eingerichtet, dass sie einen oder mehrere Servosensoren erfassen kann und einen Positionsfehler zwischen dem Kopf und einer gewünschten Position bezüglich der festgelegten Servospur(en) bestimmen kann. Eine Servosteuerung erfasst die seitliche Verschiebungsauslenkung der festgelegten Servospur(en); bestimmt einen maximalen positiven Höchstwert und einen maximalen negativen Höchstwert der seitlichen Verschiebungsauslenkung; und positioniert den Grobaktor im Wesentlichen an einem Mittelpunkt des maximalen positiven Höchstwertes und des maximalen negativen Höchstwertes der seitliche Verschiebungsauslenkung der festgelegten Servospur(en). Somit folgt der Feinaktor ...

Variabler Schreibstopp-Schwellwert

Ein Datenspeichersystem gemäß einer Ausführungsform beinhaltet einen Kopf; einen Antriebsmechanismus zum Führen eines Mediums über den Kopf; eine elektrisch mit dem Kopf verbundene Steuereinheit; eine Logik zum periodischen Ermitteln eines Schreibstopp-Schwellwerts beruhend auf einem aktuellen Positionsfehlersignal-Abtastwert; eine Logik zum Ermitteln, ob der aktuelle Positionsfehlersignal-Abtastwert den Schreibstopp-Schwellwert überschreitet; eine Logik zum Deaktivieren des Schreibens, wenn der aktuelle Positionsfehlersignal-Abtastwert den Schreibstopp-Schwellwert überschreitet; und eine Logik zum Aktivieren des Schreibens, wenn der aktuelle Positionsfehlersignal-Abtastwert den Schreibstopp-Schwellwert nicht überschreitet. Es werden auch zusätzliche Ausführungsformen offenbart.

Das Einbeziehen auswählbarer Anwendungslinks in Konversationen mit persönlichen Assistenz-Modulen

Verfahren, Vorrichtungen, Systeme und computerlesbare Medien werden für Folgendes bereitgestellt: das Betreiben einer Instanz eines persönlichen Assistenzmoduls, um einem Benutzer zu dienen, während der Benutzer das Client-Computergerät betreibt, wobei die Instanz des persönlichen Assistenzmoduls über einen Zugriff auf einen persistenten Datensatz eines Nachrichtenaustausch-Threads zwischen dem Benutzer und der (den) Instanz(en) des persönlichen Assistenzmoduls verfügt; das Erfassen von Signalen, die vom persistenten Nachrichtenaustausch-Thread ausgesendet werden; das Identifizieren der Kandidaten-Anwendung(en), die auf einem Client-Computergerät, das vom Benutzer betrieben wird, installiert sind, wobei die eine oder die mehreren Kandidaten-Anwendungen Inhalten des Nachrichtenaustausch-Threads zugewiesen sind; und das Einbeziehen des auswählbaren Links, der vom Benutzer operabel ist, in eine Abschrift des Nachrichtenaustausch-Threads, der in einer grafischen Benutzerschnittstelle angezeigt ...

Variabler Schreibstopp-Schwellenwert mit variablem Glättungsfaktor

Bei einer Ausführungsform beinhaltet ein Datenspeichersystem einen Kopf; einen Antriebsmechanismus zum Führen eines Mediums über den Kopf; eine Steuereinheit, die mit dem Kopf elektrisch verbunden ist; in die Steuereinheit codiert oder dieser zur Verfügung stehende Logik zum: periodischen Ermitteln eines Schreibstopp-Schwellenwerts auf der Grundlage einer Standardabweichung oder einer Varianz eines momentanen Positionsfehlersignal-Abtastwerts, wobei ein Glättungsfaktor, der auf eine nachfolgende Berechnung der Standardabweichung oder Varianz angewendet wird, zumindest teilweise auf der Grundlage einer momentanen Größe der Standardabweichung oder der Varianz verändert wird; Ermitteln, ob der momentane Positionsfehlersignal-Abtastwert den Schreibstopp-Schwellenwert überschreitet; Deaktivieren des Schreibens, wenn der momentane Positionsfehlersignal-Abtastwert den Schreibstopp-Schwellenwert überschreitet; und Aktivieren des Schreibens, wenn der momentane Positionsfehlersignal-Abtastwert den ...

Einbindung von auswählbaren Anwendungsverknüpfungen in Nachrichtenaustausch-Threads

Verfahren, Vorrichtungen, Systeme und computerlesbare Medien sind vorgesehen, um Anwendungsverknüpfungen in Nachrichtenaustausch-Threads einzubinden. Ein oder mehrere Stichwörter, die von einem Nachrichtenaustausch-Thread mit zwei oder mehreren Nachrichtenaustausch-Clients ausgehen, können erfasst werden. Das eine oder die mehreren Stichwörter können die Einbindung einer auswählbaren Verknüpfung zu einer bestimmten Anwendung in den Nachrichtenaustausch-Thread auslösen. Mindestens eine auf einem gegebenen, von einem Teilnehmer an dem Nachrichtenaustausch-Thread betriebenen Client-Computergerät installierte Kandidatenanwendung kann identifiziert werden. Die Kandidatenanwendung kann mit dem Inhalt des Nachrichtenaustausch-Threads verbunden sein. Eine auswählbare Verknüpfung kann in ein Transkript des Nachrichtenaustausch-Threads, das auf einer grafischen Benutzeroberfläche eines auf dem gegebenen Client-Computergerät ausgeführten Nachrichtenaustausch-Clients angezeigt wird, integriert werden ...

Schreiben neuer Daten einer ersten Blockgröße in einen RAID-Array, der sowohl die Parität als auch die Daten in einer zweiten Blockgröße speichert

Ein Redundante Anordnung unabhängiger Festplatten (RAID)-Controller empfängt neue zu schreibende Daten, wobei die neuen Daten in Blöcken einer ersten Blockgröße angegeben werden. Der RAID-Controller liest alte Daten und eine alte Parität, die den alten Daten entspricht, gespeichert in Blöcken einer zweiten Blockgröße, die größer in der Größe ist als die erste Blockgröße. Der RAID-Controller berechnet eine neue Parität basierend auf den neuen Daten, den alten Daten, und der alten Parität. Der RAID-Controller schreibt die neuen Daten und die neue Parität ausgerichtet auf die Blöcke der zweiten Blockgröße, wobei Teile der alten Daten, die nicht durch den RAID-Controller überschrieben werden, ebenfalls in die Blöcke der zweiten Blockgröße geschrieben werden.

Erkennung und Erfassung eines Servomusters

Ein Verfahren, ein Servosystem und ein Bandlaufwerk zum Erreichen eines Einrastens auf ein Servosignal werden bereitgestellt. Die Servosignale mindestens eines Servoelements werden überwacht, um ein gültiges Servosignal zu erkennen. Wird kein gültiges Servosignal erkannt, wird der Fein-Aktor in eine erste Richtung bewegt, bis entweder ein gültiges Servosignal erkannt wird oder die Grenze des Verfahrweges des Fein-Aktors erreicht wird. Wird ein gültiges Servosignal erkannt, wird der Fein-Aktor auf die Nulllage gesetzt und der Grob-Aktor in die erste Richtung bewegt. Wird die Grenze des Verfahrweges des Fein-Aktors erreicht, wird der Fein-Aktor zur ersten Position bewegt und der Grob-Aktor in eine zweite, der ersten Richtung entgegengesetzte Richtung bewegt.

Erweitern von Nachrichtenaustausch-Threads

Verfahren, Vorrichtungen, Systeme und computerlesbare Medien sind zum Erweitern des Nachrichtenaustausch-Threads vorgesehen. In verschiedenen Implementierungen kann ein laufender Nachrichtenaustausch-Thread zwischen zwei oder mehreren Teilnehmern, die mindestens zwei Nachrichtenaustausch-Clients betreiben, untersucht werden. Basierend auf der Untersuchung kann ein oder können mehrere Elemente zur Formulierung einer Suchabfrage identifiziert werden. In verschiedenen Implementierungen kann das eine oder können die mehreren Elemente in einer oder mehreren Nachrichten identifiziert werden, die von einem der mindestens zwei Teilnehmer zu einem anderen der mindestens zwei Teilnehmer als Teil des laufenden Nachrichtenaustausch-Threads geleitet werden, ohne dass ein Teilnehmer ein oder mehrere Elemente als Suchabfrage spezifisch identifiziert. Die Suchabfrage kann dann mit dem einen oder den mehreren identifizierten Elementen formuliert werden, und ein auf die Suchabfrage zutreffender Inhalt kann ...

Kraftfahrzeug-Sicherheitsgurt-Rückhalteanordnung

Kraftfahrzeug-Sicherheitsgurt-Rückhalteanordnung, umfassend einen kontinuierlichen Sicherheitsgurt. Wenn der Insasse sitzt, kann das Sicherheitsgurtschloss über den Körper gezogen werden, um das Schloss in Eingriff zu bringen, sodass erstens eine Vor-Aufprallkonfiguration des Sicherheitsgurts bereitgestellt wird, die gekennzeichnet ist durch einen auf den Hüften oder Oberschenkeln des Insassen liegenden Beckengurtabschnitt, wobei der Beckengurtabschnitt relativ zu einem Unterseiten-Gurtabschnitt des kontinuierlichen Sicherheitsgurt über die Sitzfläche des Sitzes hinweg nach hinten vertikal versetzt ist, und zweitens eine Aufprallkonfiguration des Sicherheitsgurts bereitgestellt wird, die dadurch gekennzeichnet ist, dass der Beckengurtabschnitt und der Unterseiten-Gurtabschnitt weniger nach hinten vertikal versetzt sind und im Wesentlichen vertikal in Bezug aufeinander ausgerichtet sind, um beim Aufprall eine in höherem Maß vertikal ausgerichtete Schlaufe des kontinuierlichen Sicherheitsgurts ...

BALLISTIC RANGING METHODS AND SYSTEMS FOR INCLINED SHOOTING

A portable system for facilitating inclined shooting of projectile weapons comprises a ranging system, an inclinometer and a processor. The ranging system measures a line-of sight range distance from a vantage point to a target that is elevated or depressed relative to the vantage point, and the inclinometer measures an inclination angle of a line of sight between the vantage point and the target. Based on information from the rangefinder and inclinometer, the processor determines a predicted altitude-compensated inclined shooting (ACIS) trajectory at the line-of sight range distance for a preselected projectile. The ACIS trajectory is based on a bullet path height correction between a bullet path height at a first altitude and a bullet path height at a second altitude, a range distance of the target from the vantage point, and selected meteorological atmospheric information. 1. A portable system for facilitating inclined shooting of projectile weapons , comprising:a ranging system capable of measuring a line-of-sight range from a current vantage point to a target that is elevated or depressed relative to the current vantage point;an inclinometer aligned in angular reference with the ranging system capable of measuring an inclination angle of a line of sight between the current vantage point and the target; anda processor in communication with the ranging system and the inclinometer, the processor capable of being configured to determine a predicted altitude-compensated inclined shooting trajectory at the line-of-sight range for a preselected projectile based on a difference in altitude between the current vantage point with respect to sea level and an altitude of a sighting-in vantage point with respect to sea level, the sighting-in vantage point being a vantage point at which a projectile weapon shooting the preselected projectile was sighted in.2. The system according to claim 1 , wherein the predicted altitude-compensated inclined shooting trajectory is based on ...

STORED-VALUE CARD WITH AUDIO CAPABILITIES

A stored-value card includes a housing, an audio circuit storing an audio file, and a speaker coupled to the audio circuit. The housing includes a first panel, a second panel spaced from and positioned opposite the first panel, and a side wall extending between the first panel and the second panel. The side wall extends substantially perpendicular to each of the first panel and the second panel such that an open cavity is formed between the first panel and the second panel. The housing further includes an account identifier signifying a financial account or record linked to the stored-value card. The audio circuit and the speaker are substantially enclosed within the open cavity of the housing. Stored-value card assemblies and methods of using a stored-value card are also disclosed. 1. A stored-value card , comprising:a housing including a first panel, a second panel spaced from and positioned opposite the first panel, and a side wall extending between the first panel and the second panel, the side wall extending substantially perpendicular to each of the first panel and the second panel such that an open cavity is formed between the first panel and the second panel, wherein the housing further includes an account identifier signifying a financial account or record linked to the stored-value card;an audio circuit storing an audio file; anda speaker coupled to the audio circuit;wherein the audio circuit and the speaker are substantially enclosed within the open cavity of the housing.2. The stored-value card of claim 1 , wherein the housing includes an aperture claim 1 , and the stored-value card further comprises a button formed separately from the housing and received within the aperture claim 1 , and further wherein when a bearer of the stored-value card interacts with the button claim 1 , the button interfaces with the audio circuit to selectively initiate playing of the audio file via the speaker.3. The stored-value card of claim 2 , further comprising a face ...

Soybean Plant And Seed Corresponding To Transgenic Event MON87701 And Methods For Detection Thereof

The present invention provides a transgenic soybean event MON87701, and cells, seeds, and plants comprising DNA diagnostic for the soybean event. The invention also provides compositions comprising nucleotide sequences that are diagnostic for said soybean event in a biological sample, probes and primers for use in detecting nucleotide sequences that are diagnostic for the presence of said soybean event in a biological sample, and methods for detecting the presence of said soybean event nucleotide sequences in a biological sample. The invention further provides methods of growing the seeds of such soybean event into soybean plants, and methods of breeding to produce soybean plants comprising DNA diagnostic for the soybean event. 111-. (canceled)12. A pair of DNA molecules comprising: a first DNA molecule and a second DNA molecule , wherein the DNA molecules are of sufficient length of contiguous nucleotides of a sequence selected from the group consisting of SEQ ID NO:3 , SEQ ID NO:4 , SEQ ID NO:5 , SEQ ID NO:6 and complements thereof to function as DNA primers or probes diagnostic for DNA extracted from soybean plant MON87701 or progeny thereof.1314-. (canceled)15. The pair of DNA molecules of claim 12 , wherein said first DNA molecule comprises 11 or more contiguous nucleotides of any portion of the transgene region of SEQ ID NO:3 or SEQ ID NO:5 claim 12 , or complement thereof claim 12 , and said second DNA molecule comprises a similar length of a 5′ flanking soybean genomic DNA region of SEQ ID NO:3 claim 12 , or complement thereof.16. The pair of DNA molecules of claim 15 , wherein said first DNA molecule comprises SEQ ID NO:9 and said second DNA molecule comprises SEQ ID NO:10.17. The pair of DNA molecules of claim 12 , wherein said first DNA molecule comprises 11 or more contiguous nucleotides of any portion of the transgene region of SEQ ID NO:4 or SEQ ID NO:5 claim 12 , or complement thereof claim 12 , and said second DNA molecule comprises a similar length ...

Ballistic Ranging Methods and Systems For Inclined Shooting

A portable system for facilitating inclined shooting of projectile weapons comprises a ranging system, an inclinometer and a processor. The ranging system measures a line-of sight range distance from a vantage point to a target that is elevated or depressed relative to the vantage point, and the inclinometer measures an inclination angle of a line of sight between the vantage point and the target. Based on information from the rangefinder and inclinometer, the processor determines a predicted altitude-compensated inclined shooting (ACIS) trajectory at the line-of sight range distance for a preselected projectile. The ACIS trajectory is based on a bullet path height correction between a bullet path height at a first altitude and a bullet path height at a second altitude, a range distance of the target from the vantage point, and selected meteorological atmospheric information. 120-. (canceled)21. A method , comprising:determining a line-of-sight range from a current vantage point to a target that is elevated or depressed relative to the current vantage point;determining an inclination angle of a line of sight between the current vantage point and the target; anddetermining a predicted altitude-compensated inclined shooting trajectory at the line-of-sight range for a preselected projectile based on a difference in altitude between the current vantage point with respect to sea level and an altitude of a sighting-in vantage point with respect to sea level, the sighting-in vantage point being a vantage point at which a projectile weapon shooting the preselected projectile was sighted in.22. The method according to claim 21 , wherein the predicted altitude-compensated inclined shooting trajectory is based on a bullet path height correction between a bullet path height at the current vantage point with respect to sea level and a bullet path height at the sighting-in vantage point with respect to sea level.23. The method according to claim 22 , wherein the bullet path ...

TRANSACTION PRODUCT WITH REMOVABLE TRANSACTION CARD

A transaction product includes a housing and a transaction card. The housing defines a storage chamber and a substantially planar surface. The substantially planar surface defines a perimeter portion and a recessed portion surrounded by, spaced from, and extending substantially parallel to the recessed portion to define a recess. The housing includes opposing tabs extending from the perimeter portion, toward each other, and partially across the recessed portion. The transaction card includes a machine-readable account identifier linking the transaction card to an account or record remote from the transaction product and having a value available for use as payment toward a purchase. The transaction card defines two opposing edges each selectively secured between the recessed portion of the substantially planar surface and a different one of the opposing tabs. 1. A transaction product , comprising:a housing defining a storage chamber and a substantially planar surface, the substantially planar surface defining a perimeter portion and a recessed portion surrounded by, spaced from, and extending substantially parallel to the recessed portion to define a recess, wherein the housing includes opposing tabs extending from the perimeter portion, toward each other, and partially across the recessed portion; anda transaction card including a machine-readable account identifier linking the transaction card to an account or record remote from the transaction product and having a value available for use as payment toward a purchase, wherein the transaction card defines two opposing edges each selectively secured between the recessed portion of the substantially planar surface and a different one of the opposing tabs.2. The transaction product of claim 1 , wherein the account identifier is a bar code connected to the housing.3. The transaction product of claim 1 , wherein the account identifier includes at least one of a bar code claim 1 , a magnetic strip claim 1 , a smart chip ...

STORED-VALUE CARD WITH MULTIPLE MEMBER HOUSING

A financial transaction card includes a first member, a second member, a side wall, at least one substantially rigid connection member, and an account identifier. The first member defines a first panel, and the second member defines a second panel. Each of the first panel and the second panel are substantially planar. The side wall extends between the first panel and the second panel such that the first panel is spaced from the second panel to define a void between the first panel and the second panel. The at least one substantially rigid connection member extends through the first member and interfaces with the second member to at least partially couple the first member to the second member. The account identifier associates the financial transaction card with an account or record having a value associated therewith. Other cards, assemblies and associated methods are also disclosed. 1. A financial transaction card comprising:a first member defining a first panel, the first panel being substantially planar;a second member defining a second panel, the second panel being substantially planar, and the second member being formed as a separate piece as compared to the first member;a side wall extending between the first panel and the second panel such that the first panel is spaced from the second panel to define a void between the first panel and the second panel;at least one substantially rigid connection member extending through the first member and interfacing with the second member to at least partially couple the first member to the second member; andan account identifier associating the financial transaction card with an account or record having a value associated therewith such that the financial transaction card is configured for use toward the purchase price of one or more of goods and services.2. The financial transaction card of claim 1 , wherein the side wall extends around a substantial entirety of a perimeter of each of the first panel and the second panel ...

NAMPT INHIBITORS

Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed. 2. The compound of claim 1 , or a therapeutically acceptable salt thereof claim 1 , wherein Ris NHC(O)NHR; and Ris hydrogen.3. The compound of claim 1 , or a therapeutically acceptable salt thereof claim 1 , wherein Ris CHNHC(O)R; and Ris hydrogen.4. The compound of claim 1 , or a therapeutically acceptable salt thereof claim 1 , wherein Ris hydrogen; and Ris CHNHC(O)NHR.5. The compound of claim 2 , or a therapeutically acceptable salt thereof claim 2 , wherein Ris hydrogen; and Ris CHNHC(O)R.65. The compound of any one of -; or a therapeutically acceptable salt thereof claims 1 , wherein Ris phenyl; wherein each Rphenyl is substituted at the para position with one substituent independently selected from the group consisting of R claims 1 , OR claims 1 , C(O)R claims 1 , NHC(O)R claims 1 , NRC(O)R claims 1 , NHS(O)R claims 1 , NHC(O)OR claims 1 , and C(O)NHR; and wherein each Rphenyl is optionally additionally substituted with one substituent independently selected from the group consisting of F claims 1 , Cl claims 1 , Br and I.75. The compound of any one of - claims 1 , or a therapeutically acceptable salt thereof claims 1 , wherein Ris thienyl; wherein each Rthienyl is substituted with one claims 1 , two claims 1 , or three substituents independently selected from the group consisting of R claims 1 , C(O)R claims 1 , NHR claims 1 , NHC(O)R claims 1 , NRC(O)R claims 1 , NHC(O)OR claims 1 , NRC(O)NHR claims 1 , C(O)NHR claims 1 , F claims 1 , Cl claims 1 , Br and I.8. The compound of claim 1 , selected from the group consisting of4-[(imidazo[1,2-a]pyridin-6-ylcarbamoyl)amino]-N-(3-methylbutyl)benzamide;4-[(imidazo[1,2-a]pyridin-7-ylcarbamoyl)amino]-N-(3-methylbutyl)benzamide;2-cyclopentyl-N-{4-[(imidazo[1,2-a]pyridin-6-ylcarbamoyl)amino]phenyl}acetamide;4-[(imidazo[1,2-a]pyridin-6-ylcarbamoyl)amino]-N-( ...

NAMPT INHIBITORS

Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed. 2. The compound of claim 1 , or a therapeutically acceptable salt thereof claim 1 , wherein Ris NHC(O)NHR; and Ris hydrogen.3. The compound of claim 1 , or a therapeutically acceptable salt thereof claim 1 , wherein Ris CHNHC(O)R; and Ris hydrogen.4. The compound of claim 1 , or a therapeutically acceptable salt thereof claim 1 , wherein Ris hydrogen; and Ris CHNHC(O)NHR.5. The compound of claim 2 , or a therapeutically acceptable salt thereof claim 2 , wherein Ris hydrogen; and Ris CHNHC(O)R.65. The compound of any one of -; or a therapeutically acceptable salt thereof claims 1 , wherein Ris phenyl; wherein each Rphenyl is substituted at the para position with one substituent independently selected from the group consisting of R claims 1 , OR claims 1 , C(O)R claims 1 , NHC(O)R claims 1 , NRC(O)R claims 1 , NHS(O)R claims 1 , NHC(O)OR claims 1 , and C(O)NHR; and wherein each Rphenyl is optionally additionally substituted with one substituent independently selected from the group consisting of F claims 1 , Cl claims 1 , Br and I.75. The compound of any one of - claims 1 , or a therapeutically acceptable salt thereof claims 1 , wherein Ris thienyl; wherein each Rthienyl is substituted with one claims 1 , two claims 1 , or three substituents independently selected from the group consisting of R claims 1 , C(O)R claims 1 , NHR claims 1 , NHC(O)R claims 1 , NRC(O)R claims 1 , NHC(O)OR claims 1 , NRC(O)NHR claims 1 , C(O)NHR claims 1 , F claims 1 , Cl claims 1 , Br and I.8. The compound of claim 1 , selected from the group consisting of4-[(imidazo[1,2-a]pyridin-6-ylcarbamoyl)amino]-N-(3-methylbutyl)benzamide;4-[(imidazo[1,2-a]pyridin-7-ylcarbamoyl)amino]-N-(3-methylbutyl)benzamide;2-cyclopentyl-N-{4-[(imidazo[1,2-a]pyridin-6-ylcarbamoyl)amino]phenyl}acetamide;4-[(imidazo[1,2-a]pyridin-6-ylcarbamoyl)amino]-N-( ...

Anti-b7-h3 antibodies and antibody drug conjugates

The invention relates to B7 homology 3 protein (B7-H3) antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

TRIAZOLE AGONISTS OF THE APJ RECEPTOR

Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: 2. The compound of claim 1 , the salt thereof claim 1 , the tautomer thereof claim 1 , or the salt of the tautomer claim 1 , wherein Q′ is selected from a pyridinyl claim 1 , pyrimidinyl claim 1 , or pyrazinyl group that is unsubstituted or is substituted with 1 claim 1 , or 2 Rsubstituents.5. The compound of claim 4 , the salt thereof claim 4 , the tautomer thereof claim 4 , or the salt of the tautomer claim 4 , wherein R is a —CH6. The compound of claim 5 , the salt thereof claim 5 , the tautomer thereof claim 5 , or the salt of the tautomer claim 5 , wherein Ris a —C-Calkyl7. The compound of claim 6 , the salt thereof claim 6 , the tautomer thereof claim 6 , or the salt of the tautomer claim 6 , wherein R is a —CH8. The compound of claim 5 , the salt thereof claim 5 , the tautomer thereof claim 5 , or the salt of the tautomer claim 5 , wherein Ris a —O—(C-Calkyl).9. The compound of claim 8 , the salt thereof claim 8 , the tautomer thereof claim 8 , or the salt of the tautomer claim 8 , wherein Ris selected from —O—CH claim 8 , —O—CHCH claim 8 , or —O—CH(CH).10. The compound of claim 1 , the salt thereof claim 1 , the tautomer thereof claim 1 , or the salt of the tautomer claim 1 , wherein R is a —CH11. The compound of claim 1 , the salt thereof claim 1 , the tautomer thereof claim 1 , or the salt of the tautomer claim 1 , wherein Ris a —C-Calkyl12. The compound of claim 11 , the salt thereof claim 11 , the tautomer thereof claim 11 , or the salt of the tautomer claim 11 , wherein R is a —CH13. The compound of claim 1 , the salt thereof claim 1 , the tautomer thereof claim 1 , or the salt of the tautomer claim 1 , wherein Ris a —O—(C-Calkyl).14. The compound of ...

TRIAZOLE AGONISTS OF THE APJ RECEPTOR

Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: 1. A compound or a pharmaceutically acceptable salt thereof , wherein the compound is(1R,2S)—N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-pyridinyl)-4H-1,2,4-triazol-3-yl)-1-methoxy-1-(5-methyl-2-pyrimidinyl)-2-propanesulfonamide;(2S,3R)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-pyridinyl)-4H-1,2,4-triazol-3-yl)-3-(5-methyl-2-pyrimidinyl)-2-butanesulfonamide;(1R,2S)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-pyridinyl)-4H-1,2,4-triazol-3-yl)-1-methoxy-1-(5-methyl-2-pyrimidinyl)-2-propanesulfonamide;(1R,2S)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-pyridinyl)-4H-1,2,4-triazol-3-yl)-1-hydroxy-1-(5-methyl-2-pyrimidinyl)-2-propanesulfonamide;(1S,2R)-1-(5-chloro-2-pyrimidinyl)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-pyridinyl)-4H-1,2,4-triazol-3-yl)-1-methoxy-2-propanesulfonamide;(1S,2R)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-pyridinyl)-4H-1,2,4-triazol-3-yl)-1-methoxy-1-(5-methyl-2-pyrazinyl)-2-propanesulfonamide;(1R,2S)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-pyridinyl)-4H-1,2,4-triazol-3-yl)-1-hydroxy-1-(5-methyl-2-pyrazinyl)-2-propanesulfonamide;(1R,2S)—N-(4-(2,6-dimethoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)-1-methoxy-1-(5-methyl-2-pyrimidinyl)-2-propanesulfonamide;(2S,3R)—N-(4-(2,6-dimethoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)-3-(5-methyl-2-pyrimidinyl)-2-butanesulfonamide;(1R,2S)-1-(5-chloro-2-pyrimidinyl)-N-(4-(2,6-dimethoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)-1-ethoxy-2-propanesulfonamide;(1R,2S)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-pyridinyl)-4H-1,2,4-triazol-3-yl)-1-ethoxy-1-(5-methyl-2-pyrimidinyl)-2-propanesulfonamide;(1S,2R)—N-(4-(2,6-dimethoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)-1-methoxy-1-(5-methyl-2-pyrazinyl)-2- ...

AUTOMATED OR ASSISTED UMPIRING OF BASEBALL GAME USING COMPUTER VISION

Methods and systems for use in automating or assisting umpiring of a baseball or softball game are described herein. A location of a strike zone is determined based on video images of a batter standing next to home plate captured by a camera. Locations of a ball traveling towards the batter, and locations of the bat being held by the batter, are autonomously tracked using computer vision based on video images captured by at least two cameras having different positions. Additionally, there are autonomous determinations of whether a location of the ball intersects with the strike zone, and whether the batter made a genuine attempt to swing the bat at the ball, and based one at least one of these determinations, there is an autonomous determination of whether a “strike” or a “ball” occurred. Additionally, an indication of whether a “strike” or a “ball” occurred is autonomously output. 1. A method for automating or assisting umpiring of a baseball or softball game comprising:receiving images of a batter, images of a bat held by the batter, and images of a ball traveling towards the batter from at least two cameras;determining a location of a strike zone based on the images of the batter;adding a strike zone graphic to the location of the strike zone on the images of the batter;autonomously tracking locations of the ball traveling towards the batter based on the images of the ball traveling towards the batter using transformations associated with the at least two cameras to determine the locations of the ball traveling towards the batter in three-dimensional (3D) space;adding an animated trail representing the locations of the ball on the images of the batter;autonomously tracking locations of the bat based on the images of the bat using transformations associated with the at least two cameras to determine locations of the bat in 3D space;autonomously determining whether a location of the bat in 3D space at a point in time is the same as a location of the ball in 3D ...

TRIAZOLE AGONISTS OF THE APJ RECEPTOR

Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: 2. The method of claim 1 , wherein the cardiovascular condition is heart failure.3. The method of claim 1 , wherein the cardiovascular condition is heart failure with reduced ejection fraction.4. The method of claim 1 , wherein the cardiovascular condition is heart failure with preserved ejection fraction.5. The method of claim 1 , wherein the cardiovascular condition is hypertension.6. The method of claim 1 , wherein the method includes administering at least one additional therapeutic agent to the subject claim 1 , wherein the additional therapeutic agent is selected from an α-blocker claim 1 , a β-blocker claim 1 , an angiotensin converting enzyme (ACE) inhibitor claim 1 , an angiotensin-receptor blocker (ARB) claim 1 , a calcium channel blocker claim 1 , a diuretic claim 1 , an inhibitor of the funny current claim 1 , a myosin activator claim 1 , or a neutral endopeptidase (NEP) inhibitor.7. The method of claim 1 , wherein the method includes administering at least one additional therapeutic agent to the subject claim 1 , wherein the additional therapeutic agent is selected from an angiotensin converting enzyme (ACE) inhibitor or an angiotensin-receptor blocker (ARB).10. The method of claim 1 , wherein Ris an unsubstituted pyridyl or is a pyridyl substituted with 1 or 2 Rsubstituents.13. The method of claim 1 , wherein Ris —H.14. The method of claim 1 , wherein Ris a phenyl claim 1 , pyridyl claim 1 , pyrimidinyl claim 1 , isoxazolyl claim 1 , indolyl claim 1 , naphthyl claim 1 , or pyridinyl any of which may be unsubstituted or substituted with 1 claim 1 , 2 claim 1 , or 3 Rsubstituents.16. The method of claim 1 , wherein Ris a phenyl substituted with 1 or 2 ...

TRIAZOLE AGONISTS OF THE APJ RECEPTOR

Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: 2. The method of claim 1 , wherein the condition is obesity or diabetes.3. The method of claim 1 , wherein the condition is diabetic nephropathy or chronic kidney disease.4. The method of claim 1 , wherein Ris an unsubstituted pyridyl or is a pyridyl substituted with 1 or 2 Rsubstituents.7. The method of claim 1 , wherein Ris —H.8. The method of claim 1 , wherein Ris a phenyl claim 1 , pyridyl claim 1 , pyrimidinyl claim 1 , isoxazolyl claim 1 , indolyl claim 1 , naphthyl claim 1 , or pyridinyl any of which may be unsubstituted or substituted with 1 claim 1 , 2 claim 1 , or 3 Rsubstituents.10. The method of claim 1 , wherein Ris a phenyl substituted with 1 or 2 Rsubstituents claim 1 , wherein the 1 or 2 Rsubstituents are —O—(C-Calkyl) groups.11. The method of claim 1 , wherein Q is selected from pyrimidinyl claim 1 , pyridyl claim 1 , isoxazolyl claim 1 , thiazolyl claim 1 , imidazolyl claim 1 , phenyl claim 1 , tetrahydropyrimidinonyl claim 1 , cyclopropyl claim 1 , cyclobutyl claim 1 , cyclohexyl claim 1 , morpholinyl claim 1 , pyrrolidinyl claim 1 , pyrazinyl claim 1 , imidazo[1 claim 1 ,2-a]pyridinyl claim 1 , pyrazolyl claim 1 , or oxetanyl any which may be unsubstituted or substituted with 1 claim 1 , 2 claim 1 , or 3 claim 1 , Rsubstituents.12. The method of claim 1 , wherein Q is a monocyclic heteroaryl group with 5 or 6 ring members containing 1 or 2 heteroatoms selected from N claim 1 , O claim 1 , or S and Q is unsubstituted or is substituted with 1 or 2 Rsubstituents.14. The method of claim 1 , wherein Ris a group of formula —(CRR)—(CRR)-Q.17. The method of claim 1 , wherein the compound is(1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-pyridinyl)-4H-1,2 ...

TRIAZOLE AGONISTS OF THE APJ RECEPTOR

Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: 2. The compound of or the salt thereof claim 1 , the tautomer thereof claim 1 , or the salt of the tautomer claim 1 , wherein Ris an unsubstituted pyridyl or is a pyridyl substituted with 1 or 2 Rsubstituents.6. The compound of or the salt thereof claim 1 , the tautomer thereof claim 1 , or the salt of the tautomer claim 1 , wherein Ris a phenyl claim 1 , pyridyl claim 1 , pyrimidinyl claim 1 , isoxazolyl claim 1 , indolyl claim 1 , naphthyl claim 1 , or pyridinyl any of which may be unsubstituted or substituted with 1 claim 1 , 2 claim 1 , or 3 Rsubstituents.7. The compound of or the salt thereof claim 6 , the tautomer thereof claim 6 , or the salt of the tautomer claim 6 , wherein Ris in each instance independently selected from CH claim 6 , —F claim 6 , —Cl claim 6 , —Br claim 6 , —CN claim 6 , —CF claim 6 , —OCH claim 6 , —OCHF claim 6 , —OCHCH claim 6 , —C(═O)OCH claim 6 , —C(═O)CH claim 6 , or N(CH).9. The compound of or the salt thereof claim 1 , the tautomer thereof claim 1 , or the salt of the tautomer claim 1 , wherein Ris a phenyl substituted with 1 or 2 Rsubstituents.10. The compound of or the salt thereof claim 9 , the tautomer thereof claim 9 , or the salt of the tautomer claim 9 , wherein the 1 or 2 Rsubstituents are —O—(C-Calkyl) groups.11. The compound of or the salt thereof claim 1 , the tautomer thereof claim 1 , or the salt of the tautomer claim 1 , wherein Q is selected from pyrimidinyl claim 1 , pyridyl claim 1 , isoxazolyl claim 1 , thiazolyl claim 1 , imidazolyl claim 1 , phenyl claim 1 , tetrahydropyrimidinonyl claim 1 , cyclopropyl claim 1 , cyclobutyl claim 1 , cyclohexyl claim 1 , morpholinyl claim 1 , pyrrolidinyl claim 1 , pyrazinyl claim ...

TRIAZOLE AGONISTS OF THE APJ RECEPTOR

Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: 2. The method of claim 1 , wherein cyclizing further comprises heating the compound of Formula V claim 1 , the salt thereof claim 1 , the tautomer thereof claim 1 , or the salt of the tautomer in the presence of the acid or the base.3. The method of claim 2 , wherein heating the compound of Formula V claim 2 , the salt thereof claim 2 , the tautomer thereof claim 2 , or the salt of the tautomer comprises heating the compound to a temperature of from 50° C. to 100° C.4. The method of claim 2 , wherein heating the compound of Formula V claim 2 , the salt thereof claim 2 , the tautomer thereof claim 2 , or the salt of the tautomer comprises heating the compound to a temperature of from 60° C. to 85° C.5. The method of any one of claim 1 , wherein the cyclizing of the compound of Formula V claim 1 , the salt thereof claim 1 , the tautomer thereof claim 1 , or the salt of the tautomer is performed in the presence of the base.6. The method of any one of claim 1 , wherein the base is a metal hydroxide.7. The method of claim 6 , wherein the metal hydroxide is selected from NaOH or LiOH.8. The method of claim 5 , wherein the cyclizing is carried out in an alcohol solvent.9. The method of claim 8 , wherein the alcohol is isopropanol.10. The method of any one of claim 1 , wherein cyclizing further comprises heating the compound of Formula V claim 1 , the salt thereof claim 1 , the tautomer thereof claim 1 , or the salt of the tautomer in the presence of the acid.11. The method of claim 10 , wherein the acid is selected from a sulfonic acid claim 10 , a carboxylic acid claim 10 , polyphosphoric acid claim 10 , phosphoric acid claim 10 , sulfuric acid claim 10 , or hydrochloric ...

THERMOPLASTIC PLANKS AND METHODS FOR MAKING THE SAME

A thermoplastic laminate plank is described wherein the thermoplastic laminate plank includes a core, a print layer, and optionally an overlay. The core includes at least one thermoplastic material and has a top surface and bottom surface wherein a print layer is affixed to the top surface of the core and an overlay layer is affixed to the top surface of the print layer. An underlay layer can be located and affixed between the bottom surface of the print layer and the top surface of the core. In addition, a method of making the thermoplastic laminate plank is further described which involves extruding at least one thermoplastic material into the shape of the core and affixing a laminate on the core, wherein the laminate comprises an overlay affixed to the top surface of the print layer and optionally an underlay layer affixed to the bottom surface of the print layer. 1. (canceled)2. A thermoplastic laminate plank , comprisinga core comprising at least one thermoplastic material, wherein said core has top surface and a bottom surface, and opposing sides,a print layer, optionally with an underlay layer, affixed to said top surface of the said core, wherein said print layer has a top surface and a bottom surface, wherein said print layer comprises a printed design; anda protective layer affixed to said top surface of said print layer,wherein said core has a tongue design on at least one edge and a groove design on at least an opposite edge, andwherein said core has a cellular foam structure.3. The thermoplastic laminate plank according to claim 2 , wherein the print layer is affixed to said top surface by an adhesive.4. The thermoplastic laminate plank according to claim 3 , wherein the adhesive is a hot melt adhesive.5. The thermoplastic laminate plank according to claim 3 , wherein the adhesive is a hot melt glue.6. The thermoplastic laminate plank according to claim 3 , wherein the adhesive is a hot melt polyurethane glue.7. The thermoplastic laminate plank ...

CLOUD-OFFLOADED GLOBAL SATELLITE POSITIONING

Some implementations provide low power reduced sampling of global positioning system (GPS) locations. A server may be configured to assist a mobile device in determining a location from a plurality of small GPS signal chunks and corresponding time stamps. For instance, the server may identify a set of satellites from each of the GPS signal chunks and by comparing the set of satellites for each of the GPS signal chunks to each other to determine a second set of satellites. The server may then estimate a location of the mobile based on the second set of satellites. 1. A computing device comprising:one or more processors; and receiving a plurality of chunks of global positioning system (GPS) signal samples;', 'searching for satellite specific Coarse/Acquisition (C/A) codes in the plurality of chunks over code phase and Doppler frequency combinations to identify visible satellites;', 'calculating, for each of the visible satellites, a difference between a first code phase and a second code phase, the first code phase associated with a first one of the plurality of chunks and the second code phase associated with a second one of the plurality of chunks;', 'adding each visible satellite where this difference is less than a threshold difference to a set of satellites; and', 'estimating a location based in part on the set of satellites., 'one or more computer-readable media maintaining instructions executable by the one or more processors to perform operations that include2. The computing device as recited in claim 1 , further comprising:determining which, if any, of the visible satellites whose difference in the code phases is greater than the threshold difference may be added to the set of satellites based on data related to the location; andre-estimating the location based in part on the added satellites.3. The computing device as recited in claim 1 , wherein the searching for the satellite specific C/A codes is performed independently on each of the chunks.4. The ...

TRANSACTION PRODUCT WITH MOVABLE MEMBER

A transaction product includes a primary member, an auxiliary member, and a machine-readable account identifier. The primary member defines a first panel and a second panel, the first panel defines two or more embossed sections defining interior ledge segments that define a track therebetween, and the first and second panels are coupled to one another such that the track is interposed between the first and second panels. The auxiliary member is interposed between the first and second panels, is partially positioned within the track, and is configured to move within the track in one or more of a first direction and a second direction. Movement of the auxiliary member is limited by interaction between the auxiliary member and the interior ledge segments of the two or more embossed sections. The machine-readable account identifier links the primary member to an account or record and is secured to the primary member. 1. A transaction product comprising: the first panel and the second panel are each substantially planar,', 'the first panel defines two or more embossed sections defining interior ledge segments facing one another to define a track therebetween, and', 'the first panel and the second panel are coupled to one another such that the track is interposed between the first panel and the second panel;, 'a primary member defining a first panel and a second panel, wherein the auxiliary member is configured to move within the track in one or more of a first direction and a second direction relative to the primary member, and', 'movement of the auxiliary member is limited in each of the one or more of the first direction and the second direction by interaction between the auxiliary member and the interior ledge segments of the two or more embossed sections; and, 'an auxiliary member interposed between the first panel and the second panel and at least partially positioned within the track, whereina machine-readable account identifier linking the primary member to an ...

Compositions for inactivating pathogenic microorganisms, methods of making the compositions, and methods of use thereof

Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided.

COMPOSITIONS FOR INACTIVATING PATHOGENIC MICROORGANISMS, METHODS OF MAKING THE COMPOSITIONS, AND METHODS OF USE THEREOF

Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided. 181.-. (canceled)82. A composition comprising a nanoemulsion or a dilution thereof , the nanoemulsion consisting essentially of:(a) about 3% to about 15% by volume polysorbate 80;(b) about 3% to about 15% by volume ethanol;(c) 0.5% to about 7% by volume cetylpyridium chloride;(d) about 30% to about 90% by volume soybean oil; and(e) the balance is water,wherein the nanoemulsion particles have an average diameter of less than about 200 nm and the nanoemulsion has a milky white appearance.83. A composition comprising a nanoemulsion or a dilution thereof , the nanoemulsion consisting essentially of:(a) about 5 to about 10 vol % by volume polysorbate 80;(b) about 5% to about 10 vol % by volume ethanol;(c) about 0.5% to about 3% by volume cetylpyridium chloride;(d) about 60% to about 80 vol % oil by volume soybean oil; and(e) the balance is water,wherein the nanoemulsion particles have an average diameter of less than about 200 nm and the nanoemulsion has a milky white appearance.84. A composition comprising a nanoemulsion or a dilution thereof , the nanoemulsion consisting essentially of:(a) about 5% by volume polysorbate 80;(b) about 6% to about 8% by volume ethanol;(c) about 1% by volume cetylpyridium chloride;(d) about 64% by volume soybean oil; and(e) the balance is water,wherein the nanoemulsion particles having an average diameter of less than about 200 nm, and the nanoemulsion has a milky white appearance.85. The composition of further comprising about 100 μM to about 10 mM of ethylenediaminetetraacetic acid.86. The composition of comprising about 2 mM ethylenediaminetetraacetic acid.87. The ...

BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same

The present disclosure concerns Bcl-xL inhibitors having low cell permeability, antibody drug conjugates (ADCs) comprising the inhibitors, synthons useful for synthesizing the ADCs, compositions comprising the inhibitors or ADCs, and various methods of using the inhibitors and ADCs.

Methods and Systems for Generating a Transaction Lifecycle Output for a Payment Card Transaction

Systems and methods for generating a transaction lifecycle output using a transaction lifecycle (TL) computer system are provided herein. The TL computer system includes a memory device for storing data and a processor in communication with the memory device. The processor is programmed to receive transaction data associated with a transaction being processed over a payment network. The transaction data includes authorization data, clearing data, and fraud data. The processor is also programmed to generate the transaction lifecycle output by processing the authorization data, the clearing data, and the fraud data. The transaction lifecycle output includes output data organized by pre-defined stages of the transaction. 1. A transaction lifecycle (TL) computer system for generating a transaction lifecycle output , said TL computer system comprising:a memory device for storing data; and receive transaction data associated with a transaction being processed over a payment network, the transaction data including authorization data, clearing data, and fraud data; and', 'generate the transaction lifecycle output by processing the authorization data, the clearing data, and the fraud data, wherein the transaction lifecycle output includes output data organized by pre-defined stages of the transaction., 'a processor in communication with said memory device, said processor programmed to2. A system in accordance with claim 1 , wherein said processor is further programmed to receive dispute stage data associated with the transaction claim 1 , the dispute stage data including at least one of retrieval data claim 1 , chargeback data claim 1 , second presentment data claim 1 , and case filing data.3. A system in accordance with claim 1 , wherein said processor is further programmed to:retrieve the transaction data from the payment card network; andstore the authorization data in an authorization details database, the clearing data in a clearing details database, and the fraud data ...

METHODS AND SYSTEMS FOR GENERATING A TRANSACTION LIFECYCLE OUTPUT FOR A PAYMENT CARD TRANSACTION

Systems and methods for generating a transaction lifecycle output using a transaction lifecycle (TL) computer system are provided herein. The TL computer system includes a memory device for storing data and a processor in communication with the memory device. The processor is programmed to receive transaction data associated with a transaction being processed over a payment network. The transaction data includes authorization data, clearing data, and fraud data. The processor is also programmed to generate the transaction lifecycle output by processing the authorization data, the clearing data, and the fraud data. The transaction lifecycle output includes output data organized by pre-defined stages of the transaction. 121.-. (canceled)22. A user device for displaying a transaction lifecycle for each of a plurality of disputed payment card transactions associated with a user , the plurality of disputed payment card transactions initiated over a payment network , each of the disputed payment card transactions associated with a respective payment card , each payment card issued by an issuer to a cardholder , said user device comprising:a memory device for storing data;a graphical user interface; anda processor in communication with said memory device and said graphical user interface, said processor programmed to:transmit a credential to a dispute processing platform, wherein the credential enables the user to access the dispute processing platform;receive, from the dispute processing platform in response to transmission of the credential, a respective transaction lifecycle output for each of the plurality of disputed payment card transactions, wherein the transaction lifecycle output for each disputed payment card transaction includes transaction authorization data retrieved from a first database, transaction clearing data retrieved from a second database, transaction fraud data retrieved from a third database, and dispute stage data associated with at least one of a ...

FINANCIAL TRANSACTION PRODUCT WITH ELECTRICAL ASSEMBLY AND FACE PANEL

A financial transaction product includes a housing, an electrical assembly, a button, a face panel, and an account identifier. The housing includes a panel having an outside surface. The electrical assembly is maintained within the housing and includes an activation switch and at least one of a light and a speaker. Movement of the activation switch causes activation of the electrical assembly including at least one of illumination of the light and audio emission via the speaker. The button is separate from the housing and the electrical assembly and positioned over the activation switch. The face panel is formed separately from the housing and secured to the outside surface extending over the button such that user interaction with the activation switch is performed at least partially via the face panel and the button. The account identifier is coupled with the housing and associates the product with an account or record. 1. A financial transaction product comprising:a housing including a primary panel having an outside surface;an electrical assembly maintained within the housing, wherein the electrical assembly includes an activation switch and at least one of a light and a speaker, and movement of the activation switch causes activation of the electrical assembly including at least one of illumination of the light and audio emission via the speaker;a button formed separately from the housing and the electrical assembly, the button being positioned over the activation switch;a face panel formed separately from the housing and secured to the outside surface, wherein the face panel extends over the button such that the button is hidden and user interaction with the activation switch is performed at least partially via the face panel and the button; andan account identifier coupled with the housing and associating the financial transaction product with an account or record having a value associated therewith such that the financial transaction product is configured for ...

THERMOPLASTIC PLANKS AND METHODS FOR MAKING THE SAME

A thermoplastic laminate plank is described wherein the thermoplastic laminate plank includes a core, a print layer, and optionally an overlay. The core includes at least one thermoplastic material and has a top surface and bottom surface wherein a print layer is affixed to the top surface of the core and an overlay layer is affixed to the top surface of the print layer. An underlay layer can be located and affixed between the bottom surface of the print layer and the top surface of the core. In addition, a method of making the thermoplastic laminate plank is further described which involves extruding at least one thermoplastic material into the shape of the core and affixing a laminate on the core, wherein the laminate comprises an overlay affixed to the top surface of the print layer and optionally an underlay layer affixed to the bottom surface of the print layer. 1. (canceled)2. An engineered waterproof plank comprising:(a) a wear layer adhered to a top surface of a waterproof core;(b) a first waterproof adhesive layer bonding the wear layer to the top surface of the waterproof core;(c) the waterproof core comprising an extruded dust and plastic composite;(d) the plank having a first edge with a groove extending laterally into the waterproof core and a second opposite edge with a lateral protrusion from the waterproof core, wherein the groove and protrusion have profiles shaped to form a click-lock edge fastening system.3. The plank of wherein the wear layer is selected from the group consisting of tile veneer claim 2 , stone veneer claim 2 , rubber claim 2 , decorative plastic claim 2 , linoleum and decorative vinyl.4. The plank of further comprising an underlayer selected from the group consisting of cork claim 2 , rubber claim 2 , foam and waterproof balance paper.5. The plank of further comprising a second waterproof adhesive layer bonding the underlayer to a bottom surface of the waterproof core.6. The plank of further comprising a cover layer over the wear ...

Compounds for use in preparing heterocyclic triazole agonists of the apj receptor

Compounds of Formula V, salts thereof, tautomers thereof, and salts of the tautomers have the following structure and are useful compounds in preparing small molecule agonists of the APJ Receptor: where the definitions of the variables are provided herein.

SOYBEAN TRANSGENIC EVENT MON87751 AND METHODS FOR DETECTION AND USE THEREOF

The invention provides a transgenic event MON87751, plants, plant cells, seeds, plant parts, progeny plants, and commodity products comprising event MON87751. The invention also provides polynucleotides specific for event MON87751, plants, plant cells, seeds, plant parts, and commodity products comprising polynucleotides for event MON87751. The invention also provides methods related to event MON87751. 14-. (canceled)5. A recombinant DNA molecule comprising a nucleotide sequence selected from the group consisting of SEQ ID NO:22 , SEQ ID NO:23 , SEQ ID NO:24 , and SEQ ID NO:25.6. (canceled)7. A method of detecting the presence of a DNA molecule diagnostic for soybean event MON87751 DNA in a sample , said method comprising{'claim-ref': {'@idref': 'CLM-00005', 'claim 5'}, 'detecting the presence of the recombinant DNA molecule of in said sample.'}825-. (canceled)26. A soybean plant cell comprising the recombinant DNA molecule of .27. A soybean plant part comprising the recombinant DNA molecule of .28. A soybean plant comprising the recombinant DNA molecule of .29. A microorganism comprising the recombinant DNA molecule of .30. A method of producing soybean seed comprising crossing the plant of with itself or a second soybean plant. This application claims the benefit of U.S. provisional application No. 61/834,899 filed Jun. 14, 2013, which is herein incorporated by reference in its entirety.The Sequence listing contained in the file named MONS357US_ST25.txt, which is 42.9 kilobytes (size as measured in Microsoft Windows®), and was created on May 28, 2014, is filed herewith by electronic submission and is incorporated by reference herein.The invention relates to a transgenic (soybean) event referred to as MON87751. The event provides two different modes of action of resistance from lepidopteran infestations of soybean by providing a unique combination of insecticidal toxin proteins not previously available in soybean plants. The combination of these insecticidal toxin ...

AUTOMATED OR ASSISTED UMPIRING OF BASEBALL GAME USING COMPUTER VISION

Methods and systems for use in automating or assisting umpiring of a baseball or softball game are described herein. A location of a strike zone is determined based on video images of a batter standing next to home plate captured by a camera. Locations of a ball traveling towards the batter, and locations of the bat being held by the batter, are autonomously tracked using computer vision based on video images captured by at least two cameras having different positions. Additionally, there are autonomous determinations of whether a location of the ball intersects with the strike zone, and whether the batter made a genuine attempt to swing the bat at the ball, and based one at least one of these determinations, there is an autonomous determination of whether a “strike” or a “ball” occurred. Additionally, an indication of whether a “strike” or a “ball” occurred is autonomously output. 1. A method for automating or assisting umpiring of a baseball game or a softball game comprising:receiving images of a batter, images of a bat held by the batter, and images of a ball from at least two cameras;determining a location of a strike zone based on the images of the batter;adding a strike zone graphic to the location of the strike zone on the images of the batter;tracking locations of the ball in three-dimensional (3D) space;adding an animated trail representing the locations of the ball on the images of the batter;tracking locations of the bat to determine locations of the bat in 3D space;determining whether a location of the bat in 3D space at a point in time is the same as a location of the ball in 3D space at the point in time;determining whether at least one location of the ball intersected with the strike zone based on the determined location of the strike zone and the tracked locations of the ball;determining whether a “strike” or a “ball” occurred;displaying the strike zone graphic and the animated trail on an output display device; andindicating whether a “strike” or a ...

THERMOPLASTIC PLANKS AND METHODS FOR MAKING THE SAME

A thermoplastic laminate plank is described wherein the thermoplastic laminate plank includes a core, a print layer, and optionally an overlay. The core includes at least one thermoplastic material and has a top surface and bottom surface wherein a print layer is affixed to the top surface of the core and an overlay layer is affixed to the top surface of the print layer. An underlay layer can be located and affixed between the bottom surface of the print layer and the top surface of the core. In addition, a method of making the thermoplastic laminate plank is further described which involves extruding at least one thermoplastic material into the shape of the core and affixing a laminate on the core, wherein the laminate comprises an overlay affixed to the top surface of the print layer and optionally an underlay layer affixed to the bottom surface of the print layer. 1a core comprising at least one thermoplastic material, wherein said core has a top surface and a bottom surface, and opposing sides;a print layer affixed to said top surface of said core, wherein said print layer has a top surface and a bottom surface; anda protective layer affixed to said top surface of said print layer, wherein said at least bottom surface of the core is thermally treated.. A thermoplastic laminate plank comprising: This application is a continuation of U.S. application Ser. No. 13/230,979, filed on Sep. 13, 2011, which is a continuation of U.S. application Ser. No. 12/825,447, filed on Jun. 29, 2010, now U.S. Pat. No. 8,021,741, which is a continuation of U.S. application Ser. No. 12/196,488, filed on Aug. 22, 2008, now U.S. Pat. No. 7,762,345, which is a continuation of U.S. application Ser. No. 11/788,421, filed on Apr. 20, 2007, now U.S. Pat. No. 7,419,717, which is a division of U.S. application Ser. No. 10/104,383, filed on Mar. 22, 2002, now U.S. Pat. No. 7,211,310, which is a division of U.S. patent application Ser. No. 09/460,928, filed Dec. 14, 1999, now U.S. Pat. No. 6,617 ...

Soybean transgenic event mon87751 and methods for detection and use thereof

The invention provides a transgenic Glycine max event MON87751, plants, plant cells, seeds, plant parts, progeny plants, and commodity products comprising event MON87751. The invention also provides polynucleotides specific for event MON87751, plants, plant cells, seeds, plant parts, and commodity products comprising polynucleotides for event MON87751. The invention also provides methods related to event MON87751.

Standing secondary and ergonomic toilets

A secondary standing toilet includes a back wall, a water dispenser for providing a waterfall feature along the back wall, doors configured to open and close relative to the back wall, and a floor configured to raise and lower. An ergonomic toilet including a base rotatably supported about a drain tube, and a seat supported by the base and vertically adjustable.

HETEROCYCLIC TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR

Compounds of Formula I and Formula II, pharmaceutically acceptable salts thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: 2. The compound of or the pharmaceutically acceptable salt thereof claim 1 , the tautomer thereof claim 1 , the pharmaceutically acceptable salt of the tautomer claim 1 , the stereoisomer of any of the foregoing claim 1 , or the mixture thereof claim 1 , wherein one of the following is true:{'sup': 1a', '1', '1a′, '1) two Rsubstituents on adjacent carbon atoms or on an adjacent carbon atom and an adjacent N atom of a 5- or 6-membered heterocyclic Rgroup join to form a 6 membered ring that may be saturated, partially saturated, or aromatic and may include 0, 1, or 2 N atoms and may further optionally be substituted with 1 or 2 Rsubstituents and may include an oxo substituent if the ring is not an aromatic ring; or'}{'sup': 1a', '1', '1a′, '2) two Rsubstituents on adjacent carbon atoms or on an adjacent carbon atom and an adjacent N atom of a 5- or 6-membered heterocyclic Rgroup join to form a 5 membered ring that may be saturated, partially saturated, or aromatic and may include 0, 1, or 2 heteroatoms selected from N, O, or S and may further optionally be substituted with 1 or 2 Rsubstituent and may include an oxo substituent if the ring is not an aromatic ring.'}4. The compound of or the pharmaceutically acceptable salt thereof claim 1 , the stereoisomer of any of the foregoing claim 1 , or the mixture thereof claim 1 , wherein Ris selected from a straight or branched chain C-Calkyl group that is unsubstituted or is substituted with 1 claim 1 , 2 claim 1 , or 3 Rsubstituents.7. The compound of or the pharmaceutically acceptable salt thereof claim 1 , the tautomer thereof claim 1 , the pharmaceutically acceptable salt of the tautomer claim 1 , the stereoisomer of ...

TRIAZOLE AGONISTS OF THE APJ RECEPTOR

Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: 2. The compound of or the pharmaceutically acceptable salt thereof claim 1 , wherein Ris an unsubstituted pyridyl or is a pyridyl substituted with 1 or 2 Rsubstituents.6. The compound of or the pharmaceutically acceptable salt thereof claim 1 , wherein Ris —H.7. The compound of or the pharmaceutically acceptable salt thereof claim 1 , wherein Ris a phenyl claim 1 , pyridyl claim 1 , pyrimidinyl claim 1 , isoxazolyl claim 1 , indolyl claim 1 , or naphthyl any of which may be unsubstituted or substituted with 1 claim 1 , 2 claim 1 , or 3 Rsubstituents.8. The compound of or the pharmaceutically acceptable salt thereof claim 7 , wherein Ris in each instance independently selected from —CH claim 7 , —F claim 7 , —Cl claim 7 , —Br claim 7 , —CN claim 7 , —CF claim 7 , —OCH claim 7 , —OCHF claim 7 , —OCHCH claim 7 , —C(═O)OCH claim 7 , —C(═O)CH claim 7 , or —N(CH).10. The compound of or the pharmaceutically acceptable salt thereof claim 1 , wherein Ris a phenyl substituted with 1 or 2 Rsubstituents.11. The compound of or the pharmaceutically acceptable salt thereof claim 10 , wherein the 1 or 2 Rsubstituents are —O—(C-Calkyl) groups.12. The compound of or the pharmaceutically acceptable salt thereof claim 1 , wherein Ris selected from a group of formula —(CRR)-Q claim 1 , a group of formula —NH—(CRR)-Q claim 1 , a group of formula —(CRR)—C(═O)-Q claim 1 , a group of formula —(CRR)—(CRR)-Q claim 1 , a group of formula —(CR═CR)-Q claim 1 , or a group of formula -(heterocyclyl)-Q claim 1 , wherein the heterocyclyl of the -(heterocyclyl)-Q has 5 to 7 ring members of which 1 claim 1 , 2 claim 1 , or 3 are heteroatoms selected from N claim 1 , O claim 1 , or S and is unsubstituted ...

BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same

The present disclosure concerns Bcl-xL inhibitors having low cell permeability, antibody drug conjugates (ADCs) comprising the inhibitors, synthons useful for synthesizing the ADCs, compositions comprising the inhibitors or ADCs, and various methods of using the inhibitors and ADCs.

TRIAZOLE AGONISTS OF THE APJ RECEPTOR

Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: 2. The compound of or the pharmaceutically acceptable salt thereof claim 1 , the stereoisomer of any of the foregoing claim 1 , or the mixture thereof claim 1 , wherein Ris an unsubstituted pyridyl or is a pyridyl substituted with 1 or 2 Rsubstituents.6. The compound of or the pharmaceutically acceptable salt thereof claim 1 , the stereoisomer of any of the foregoing claim 1 , or the mixture thereof claim 1 , wherein Ris —H.7. The compound of or the pharmaceutically acceptable salt thereof claim 1 , the stereoisomer of any of the foregoing claim 1 , or the mixture thereof claim 1 , wherein Ris a phenyl claim 1 , pyridyl claim 1 , pyrimidinyl claim 1 , isoxazolyl claim 1 , indolyl claim 1 , naphthyl claim 1 , or pyridinyl any of which may be unsubstituted or substituted with 1 claim 1 , 2 claim 1 , or 3 Rsubstituents.8. The compound of or the pharmaceutically acceptable salt thereof claim 7 , the stereoisomer of any of the foregoing claim 7 , or the mixture thereof claim 7 , wherein Ris in each instance independently selected from —CH claim 7 , —F claim 7 , —Cl claim 7 , —Br claim 7 , —CN claim 7 , —CF claim 7 , —OCH claim 7 , —OCHF claim 7 , —OCHCH claim 7 , —C(═O)OCH claim 7 , —C(═O)CH claim 7 , or —N(CH).10. The compound of or the pharmaceutically acceptable salt thereof claim 1 , the stereoisomer of any of the foregoing claim 1 , or the mixture thereof claim 1 , wherein Ris a phenyl substituted with 1 or 2 Rsubstituents.11. The compound of or the pharmaceutically acceptable salt thereof claim 10 , the stereoisomer of any of the foregoing claim 10 , or the mixture thereof claim 10 , wherein the 1 or 2 Rsubstituents are —O—(C-Calkyl) groups.12. The compound of or the ...

AUTOMATED OR ASSISTED UMPIRING OF BASEBALL GAME USING COMPUTER VISION

Methods and systems for use in automating or assisting umpiring of a baseball or softball game are described herein. A location of a strike zone is determined based on video images of a batter standing next to home plate captured by a camera. Locations of a ball traveling towards the batter, and locations of the bat being held by the batter, are autonomously tracked using computer vision based on video images captured by at least two cameras having different positions. Additionally, there are autonomous determinations of whether a location of the ball intersects with the strike zone, and whether the batter made a genuine attempt to swing the bat at the ball, and based one at least one of these determinations, there is an autonomous determination of whether a “strike” or a “ball” occurred. Additionally, an indication of whether a “strike” or a “ball” occurred is autonomously output. 1. A method for use in automating or assisting umpiring of a baseball or softball game , comprising:(a) receiving video images, captured using at least one camera, of a batter standing next to home plate;(b) determining, based on the video images of the batter standing next to home plate, a location of a strike zone;(c) receiving video images, captured using at least two different cameras having different positions, of a ball traveling towards the batter for which the strike zone was determined;(d) receiving video images, captured using at least two different cameras having different positions, of a bat being held by the batter as the ball travels towards the batter, wherein at least some of the video images of the bat being held by the batter may or may not be the same as at least some of the video images of the ball traveling towards the batter;(e) autonomously tracking locations of the ball traveling towards the batter, using computer vision, based on the video images of the ball traveling towards the batter;(f) autonomously tracking locations of the bat being held by the batter as the ...

SOYBEAN TRANSGENIC EVENT MON87751 AND METHODS FOR DETECTION AND USE THEREOF

The invention provides a transgenic event MON87751, plants, plant cells, seeds, plant parts, progeny plants, and commodity products comprising event MON87751. The invention also provides polynucleotides specific for event MON87751, plants, plant cells, seeds, plant parts, and commodity products comprising polynucleotides for event MON87751. The invention also provides methods related to event MON87751. 14-. (canceled)5. A pair of DNA molecules comprising a first DNA molecule and a second DNA molecule different from the first DNA molecule that function as DNA primers when used together in an amplification reaction with a sample containing soybean event MON87751 template DNA to produce an amplicon diagnostic for said soybean event MON87751 DNA in said sample , wherein said amplicon comprises the nucleotide sequence selected from the group consisting of SEQ ID NO:1 , SEQ ID NO:2 , SEQ ID NO:3 , SEQ ID NO:4 , SEQ ID NO:5 , SEQ ID NO:6 , SEQ ID NO:7 , SEQ ID NO:8 , SEQ ID NO:9 , SEQ ID NO:10 , SEQ ID NO:17 , SEQ ID NO:18 , SEQ ID NO:19 , SEQ ID NO:20 , SEQ ID NO:21 , SEQ ID NO:22 , SEQ ID NO:23 , SEQ ID NO:24 , SEQ ID NO:25 , and SEQ ID NO:26.6. (canceled)7. A method of detecting the presence of a DNA segment diagnostic for soybean event MON87751 DNA in a sample , said method comprising:{'claim-ref': {'@idref': 'CLM-00005', 'claim 5'}, 'a) contacting said sample with the pair of DNA molecules of ;'}b) performing an amplification reaction sufficient to produce a DNA amplicon; andc) detecting the presence of said DNA amplicon in said reaction,wherein said DNA amplicon comprises the nucleotide sequence selected from the group consisting of SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, SEQ ID NO:6, SEQ ID NO:7, SEQ ID NO:8, SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:17, SEQ ID NO:18, SEQ ID NO:19, SEQ ID NO:20, SEQ ID NO:21, SEQ ID NO:22, SEQ ID NO:23, SEQ ID NO:24, SEQ ID NO:25, and SEQ ID NO:26, and wherein said detecting the presence of said amplicon is ...

Defined systems for epithelial cell culture and use thereof

The present invention provides cell culture media formulations which support the in vitro cultivation of animal epithelial cells. The media comprise at least one fibroblast growth factor (FGF) and at least one agent that induces increased intracellular cAMP levels, and optionally comprise ascorbic acid. The present invention also provides methods of cultivating animal epithelial cells in vitro using these cell culture media formulations, kits comprising the media, cell culture compositions comprising the culture media and an animal epithelial cell, and compositions that may be used as replacements for organ or gland extracts in animal cell culture media.

Anti-b7-h3 antibodies and antibody drug conjugates

The invention relates to B7 homology 3 protein (B7-H3) antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

Bcl-xL inhibitory compounds and antibody drug conjugates including the same

Small molecule Bcl-xL inhibitorsand Antibody Drug Conjugates (ADCs) comprising small molecule Bcl-xL inhibitors are disclosed herein. The Bcl-xL inhibitors and ADCs of the disclosure are useful for, among other things, inhibiting anti-apoptotic Bcl xL proteins as a therapeutic approach towards the treatment of diseases that involve a dysregulated apoptosis pathway.

Anti-b7-h3 antibodies and antibody drug conjugates

The invention relates to B7 homology 3 protein (B7-H3) antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

Anti-cd98 antibodies and antibody drug conjugates

The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

Anti-B7-H3 antibodies and antibody drug conjugates

The invention relates to B7 homology 3 protein (B7-H3) antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

Anti-EGFR antibody drug conjugates

The invention relates to anti-Epidermal Growth Factor Receptor (EGFR) antibody drug conjugates (ADCs) which inhibit Bcl-xL, including compositions and methods of using said ADCs. Formula (IIa), (IIb), (IIc)

Dual mode I. V. infusion device

A dual mode peristaltic device is provided for infusing I.V. solutions to a patient through an I.V. tube. In a first mode of operation, the device functions as a peristaltic pump and in the second mode of operation it functions like a controller. Included in the device and associated with the I.V. tube is a pressure sensing strain gauge assembly that monitors dimensional changes in the outer diameter of the I.V. tube as an indication of fluid pressure changes in the tube. The strain gauge assembly is positioned relative to the device's peristaltic means to alternately monitor fluid pressure in a patent I.V. tube upstream and downstream from the gauge assembly. In the first mode (pump mode), the device is programmed to alarm and cease operation when fluid pressure downstream from the gauge assembly reaches a preselected value. In the second mode (controller mode), the device is programmed to alarm and cease operation when there is no differential between fluid pressure upstream and downstream from the gauge assembly.

Dual mode i.v. infusion device

Domestic dryer speed control

nampt inhibitors

resumo “inibidores de nampt” são revelados compostos que inibem a atividade de nampt, composições contendo os compostos, e métodos para tratar as doenças durante as quais ocorre a expressão de nampt. abstract "nampt inhibitors" are disclosed compounds that inhibit the activity of nampt, compositions containing the compounds, and methods of treating diseases during which nampt expression occurs.

water treatment cartridge

water treatment device

Compositions for inactivating pathogenic microorganisms, methods of making the compositions, and methods of use thereof

Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided.

Nociceptin-based analgesics

The invention relates to a family of hexapeptide compounds exhibiting activity with regard to the ORL-1 receptor. The compounds share a general formula of Arg-Tyr-Tyr-Arg-Trp-Arg, and may be constructed having modifications or substitutions at any position, and may include modifications of the amino- and carboxy-termini of the hexapeptide. These compounds include agents exhibiting agonist activity and antagonist activity when exposed to the human ORL-1 receptor. As such, the hexapeptides may be useful as analgesics, anxiolytics, diuretics, and anti-cancer agents.

Nociceptin-based analgesics

The invention relates to a family of hexapeptide compounds exhibiting activity with regard to the ORL-1 receptor. The compounds share a general formula of Arg-Tyr-Tyr-Arg-Trp-Arg, and may be constructed having modifications or substitutions at any position, and may include modifications of the amino- and carboxy-termini of the hexapeptide. These compounds include agents exhibiting agonist activity and antagonist activity when exposed to the human ORL-1 receptor. As such, the hexapeptides may be useful as analgesics, anxiolytics, diuretics, and anti-cancer agents.

Drug cassette, autoinjector, and autoinjector system

A cassette for use with an injector has a housing, and a cassette identification arrangement (cassette ID) defining a code containing information about the cassette that is detectable and decipherable by an injector. The cassette may further have an integrated cassette syringe movably disposed within the housing, for holding a drug, and a locking arrangement for interlocking the integrated cassette syringe with the housing. The cassette may further have an aperture in the housing, and a cassette cap for removing a needle shield of the integrated cassette syringe. The cassette may have an anti-bending structure to prevent bending or flexing of the cassette cap. The injector may have a processor for controlling operational parameters of the injector and a detector communicatively coupled with the processor for detecting and communicating the cassette ID to the microprocessor to decipher the code defined therein.

Drug cassette

A cassette for use with an injector has a housing, and a cassette identification arrangement (cassette ID) defining a code containing information about the cassette that is detectable and decipherable by an injector. The injector may have a processor for controlling operational parameters of the injector and a detector communicatively coupled with the processor for detecting and communicating the cassette ID to the microprocessor to decipher the code defined therein.

Antibody drug conjugates with cell permeable Bcl-xL inhibitors

Small molecule Bcl-xL inhibitors and Antibody Drug Conjugates (ADCs) comprising small molecule Bcl-xL inhibitors are disclosed herein. The Bcl-xL inhibitors and ADCs of the disclosure are useful for, among other things, inhibiting anti-apoptotic Bcl xL proteins as a therapeutic approach towards the treatment of diseases that involve a dysregulated apoptosis pathway.

Barcodes with Graphical Elements

Barcodes are provided that convey images to help consumers and/or to help identify information about the origin of an article. The images conveyed by the barcodes may be associated with a merchant, a department, an event, a season, a theme or a product, for example. The barcodes may be placed on any number of articles including purchaser receipts, gift receipts, marketing receipt coupons, paper coupons, electronic coupons, rewards cards, gift cards, registry printouts, and products/packaging, for example. Under some embodiments, the barcodes help consumers to associate articles with a particular merchant or department. Under other embodiments, the barcodes help consumers to distinguish purchaser receipts from gift receipts. In some embodiments, the barcodes are generated dynamically by altering font-based barcodes to convey the image.

Process for making high grade protein product

A process for making a high grade protein product, such as a mammalian feed product, using residue slurry from a cellulose fermentation and distillation process is provided. The residue slurry is compressed to remove much of the residual liquid. The compressed slurry is shaped, dried, leavened and granulated to provide the high grade protein product. Nutrients, flavorants, texturizers and other food product-enhancing ingredients may be added during the process. The granules of animal feed product can be packaged and stored in an inert or other stable environment for extended storage periods.

Drug cassette, autoinjector, and autoinjector system

A cassette for use with an injector has a housing, and a cassette identification arrangement (cassette ID) defining a code containing information about the cassette that is detectable and decipherable by an injector. The cassette may further have an integrated cassette syringe movably disposed within the housing, for holding a drug, and a locking arrangement for interlocking the integrated cassette syringe with the housing. The cassette may further have an aperture in the housing, and a cassette cap for removing a needle shield of the integrated cassette syringe. The cassette may have an anti-bending structure to prevent bending or flexing of the cassette cap. The injector may have a processor for controlling operational parameters of the injector and a detector communicatively coupled with the processor for detecting and communicating the cassette ID to the microprocessor to decipher the code defined therein.

Anti-CD98 antibodies and antibody drug conjugates

The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

Visual incremental turn detector

A visual gyroscope system for detecting turns and straight line travel of a vehicle includes a visual image detector mounted on the vehicle, for producing sequential and successive digitized image data strips containing information identifying scenery about the vehicle at associated successive locations along the route travelled, A processor is programmed to extract from image detector each successive pair of image data strips, and rotate the second occurring strip of each pair until it matches the first occurring strip to obtain the incremental rotation and direction of rotation of the vehicle in its travel between strips. The incremental rotations between strips are accumulated and summed to obtain the total rotation upon completion of a turn, and along with the direction of rotation, identification of a right turn, left turn, u-turn, or straight line travel. Dead reckoning navigation is also provided via the inclusion of an odometer, for providing distance readings for the distance travelled between each successive image data strip.

Method and apparatus for automatically tracking the location of vehicles

A system for automatically tracking the location of a vehicle includes a visual image detector mounted on the vehicle for producing as the vehicle moves along a route digitized strips of image data representing successive panoramic views of scenery about the vehicle at respective locations along the route. A sparse tracking subsystem processes and stores only selected ones of the image data strips representing substantially spaced apart successive locations along the route, for use as a sparse database. A dense tracking subsystem processes and stores as a dense database every successive one of the image data strips representing location along the route, whereby the dense tracking subsystem provides more accurate location of the vehicle when it retraces some portion of the route than the sparse tracking subsystem. After the sparse and dense databases are established, the location of the vehicle in real time as it retraces the route is performed by the dense tracking subsystem matching current image data strips from the visual image detector with the dense database strips to determine the location of the vehicle, as long as the vehicle stays on the pre-established route. If the vehicles strays from the route, the system senses the deviation and switches to the sparse tracking system to search a broader area in less time than the dense tracking system to attempt to relocate the vehicle along the route, after which the system switches back to the dense tracking subsystem.

Anti-cd98 antibodies and antibody drug conjugates

The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

Anti-egfr antibody drug conjugates

The invention relates to anti-Epidermal Growth Factor Receptor (EGFR) antibody drug conjugates (ADCs) which inhibit Bcl-xL, including compositions and methods of using said ADCs. Formula (IIa), (IIb), (IIc)

Anti-b7-h3 antibodies and antibody drug conjugates

The invention relates to B7 homology 3 protein (B7-H3) antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

Anti-egfr antibody drug conjugates

The invention relates to anti-Epidermal Growth Factor Receptor (EGFR) antibody drug conjugates (ADCs) which inhibit Bcl-xL, including compositions and methods of using said ADCs.

Anti-cd98 antibodies and antibody drug conjugates

The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

Anti-egfr antibody drug conjugates

The invention relates to anti-Epidermal Growth Factor Receptor (EGFR) antibody drug conjugates (ADCs) which inhibit Bcl-xL, including compositions and methods of using said ADCs.

Anti-egfr antibody drug conjugates

The invention relates to anti-Epidermal Growth Factor Receptor (EGFR) antibody drug conjugates (ADCs) which inhibit Bcl-xL, including compositions and methods of using said ADCs.

Control system for a livestock pen panel

A control system for use with a self-locking pen paneling arrangement includes a series of retaining bars which are movable from a first access position to a first retaining position in response to downward movement of an animal's neck toward the feeding area. A movable locking member is mounted to each retaining bar, and is engageable with a latch member when the retaining member is in its first retaining position. A release mechanism is operable to disengage the locking member from the latch member to provide movement of the retaining bar to its first access position. If desired, the retaining bar can be moved to a second retaining position, distinct from the first retaining position, in which movement of the release mechanism does not disengage the locking member from the latch member. This "locks out" certain animals to prevent withdrawal from the feeding area, to enable the operator to dehorn, vaccinate or perform any other procedure, treatment or operation on the animal as necessary. Thereafter, any animals which were previously "locked out" are released by further movement of the release mechanism. Any or all of the retaining members can also be moved to a second access position providing free access to and withdrawal from the feeding area.

Apparatus for removing particulates from the exhaust gases generated in drum mixers and aggregate dryers

A wet type gas scrubber is disclosed and utilizes a ring dam or deflector ring around the periphery of the scrubber's inner tube to intercept and restrain the particulate Laden water as it flows along the outer surface of the inner tube. The deflector prevents the particulate Laden water from entering into the gas exhaust flow that is being emitted to atmosphere. The scrubber includes damper means in the gas inlet for regulating the velocity of gas through the inlet.

Bcl-xl inhibitory compounds and antibody drug conjugates including the same

Small molecule Bcl-xL inhibitorsand Antibody Drug Conjugates (ADCs) comprising small molecule Bcl-xL inhibitors are disclosed herein. The Bcl-xL inhibitors and ADCs of the disclosure are useful for, among other things, inhibiting anti-apoptotic Bcl xL proteins as a therapeutic approach towards the treatment of diseases that involve a dysregulated apoptosis pathway.

NOVEL HETEROCYCLIC DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME

LA PRESENTE INVENTION CONCERNE NOTAMMENT DES COMPOSES DE FORMULE : (CF DESSIN DANS BOPI) OU RRN EST UN PYRROLIDINO, UN PIPERIDINO OU UN HEXAMETHYLENIMINO; M VAUT 3 OU 4; R EST UN HYDROGENE OU UN METHYLE; ET R EST LE GROUPE (CH)R OU Q VAUT ZERO, 1 OU 2 ET R EST UN METHYLTHIOMETHYLE, CHNHC(B)NHCH (OU B EST NCN OU CHNO), SOME, CHNOH; OU LE GROUPE COR OU R EST UN HYDROXY, UN AMINO, UN DIMETHYLAMINO OU UN PYRROLIDINO; OU LE GROUPE CHNHSOME; OU LE GROUPE CHNHCOR5 OU R5 EST UN METHYLE OU UN PHENYLE, QUI SONT UTILES COMME MEDICAMENT AINSI QUE DES PROCEDES POUR LEUR PREPARATION. THE PRESENT INVENTION CONCERNS IN PARTICULAR COMPOUNDS OF FORMULA: (CF DRAWING IN BOPI) OR RRN IS A PYRROLIDINO, A PIPERIDINO OR A HEXAMETHYLENIMINO; M IS 3 OR 4; R IS A HYDROGEN OR A METHYL; AND R IS GROUP (CH) R OR Q IS ZERO, 1 OR 2 AND R IS METHYLTHIOMETHYL, CHNHC (B) NHCH (OR B IS NCN OR CHNO), SOME, CHNOH; OR THE COR OR R GROUP IS A HYDROXY, AMINO, DIMETHYLAMINO OR PYRROLIDINO; OR THE CHNHSOME GROUP; OR THE CHNHCOR5 OR R5 GROUP IS A METHYL OR A PHENYL, WHICH ARE USEFUL AS A MEDICINAL PRODUCT AND METHODS FOR THEIR PREPARATION.

Reciprocal chuck for paving breaker

A handheld paving breaker (1) includes a reciprocal chuck (40) in a fronthead (20) and an elastic spring (52) for biasing the chuck toward the fronthead, The chuck can move longitudinally, but is restrained from rotation in the fronthead. A moil (28) mounted in the chuck is biased against the work surface by the chuck, to provide better control of the moil, during start-up and operation. Wear pads (130 136) between the spring and members against which the spring is seated improve spring life.

Therapeutic fragments of von willebrand factor

Processes for preparing aqueous solutions of cysteine--altered von Willebrand Factor fragment which are substantially free of aggregate and capable of therapeutic use for treating thrombosis are provided. The claimed process comprises providing an aqueous solution of vWF fragment and denaturant and containing undesired contaminants, said solution having an acidic pH; separating said contaminants from said solution by contacting said solution with an affinity chromatography medium to which said vWF fragments adhere; eluting said vWF fragment from said affinity chromatography medium in the presence of the denaturant; and separating the eluted fragment from said denaturant while maintaining the aqueous solution of the fragment at a pH of about 2.5 to less than about 5.5 to increase monomerization of, and decrease aggregation of, said fragment, thereby forming an aqueous solution of vWF fragment which is substantially free of aggregate.

Apparatus for picture processing with resolution conversion

1,2,3,4- tetrahydroisoquinoline-8-carboxamide compounds and their use as apoptosis-inducing agents

Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, such as compounds having Formula (I) (see formula I) Also disclosed are compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-xL protein.

Drug cassette, autoinjector, and autoinjector system

A cassette for use with an injector has a housing, and a cassette identification arrangement (cassette ID) defining a code containing information about the cassette that is detectable and decipherable by an injector. The cassette may further have an integrated cassette syringe movably disposed within the housing, for holding a drug, and a locking arrangement for interlocking the integrated cassette syringe with the housing. The cassette may further have an aperture in the housing, and a cassette cap for removing a needle shield of the integrated cassette syringe. The cassette may have an anti-bending structure to prevent bending or flexing of the cassette cap. The injector may have a processor for controlling operational parameters of the injector and a detector communicatively coupled with the processor for detecting and communicating the cassette ID to the microprocessor to decipher the code defined therein.

Drug cassette, autoinjector, and autoinjector system

There is provided a cassette for an injector, the cassette comprising: a housing; a sleeve movably disposed within the housing, the sleeve for directly or indirectly holding a drug container; a locking arrangement for interlocking the sleeve with the housing, the locking arrangement comprising a spring-biased member associated with one of the housing and the sleeve, and a fixed member associated with the other one of the housing and the sleeve for interlocking with the spring-biased member.

Transaction product with removable transaction card

A transaction product includes a housing and a transaction card. The housing defines a storage chamber and a substantially planar surface. The substantially planar surface defines a perimeter portion and a recessed portion surrounded by, spaced from, and extending substantially parallel to the recessed portion to define a recess. The housing includes opposing tabs extending from the perimeter portion, toward each other, and partially across the recessed portion. The transaction card includes a machine-readable account identifier linking the transaction card to an account or record remote from the transaction product and having a value available for use as payment toward a purchase. The transaction card defines two opposing edges each selectively secured between the recessed portion of the substantially planar surface and a different one of the opposing tabs.

TRANSGENIC EVENT OF SOYA MON87751 AND METHODS FOR DETECTION AND USE

La invención proporciona un evento de Glycine max transgénico MON87751, plantas, células vegetales, semillas, partes de plantas, plantas de la progenie y productos básicos que comprenden el evento MON87751. La invención también proporciona polinucleótidos específicos para el evento MON87751, las plantas, las células vegetales, las semillas, las partes de plantas y los productos básicos que comprenden polinucleótidos para el evento MON87751.

Anti-eavesdrop security device

A system and method to prevent eavesdropping by a device. An anti-eavesdrop component is installed on the device. The anti-eavesdrop component is configured to actively prevent the device from capturing audio from the environment. In response to installing the anti-eavesdrop component, the device recognizes the anti-eavesdrop component as a primary audio input for the device. The anti-eavesdrop component then proceeds to block the device from capturing outside audio by injecting noise or otherwise interfering with the primary audio input.

Method of using multiple row sensing device for a tire

A method of using a sensor device for tire inspection is provided. Signals are received from multiples rows of sensors separated by a predetermined distance. The sensors are positioned next to the inner surface of the tire for inspection. Signals from the different rows of sensors are used to identify e.g., breaks in the reinforcements of the tire and also used to identify undesirable signals generated from vibration or jarring of the sensor device.

High density fiber distribution tray system

A fiber optic connector tray system for managing fiber optic cable consists of a first tray body (200a) movably connected to a second tray body (200b), and a link (260) attached to the first tray body and a mount arm (153) such that when the trays are rotated, the link causes movement of one tray relative to the other. The system provides a simple way to manage a plurality of fibers and reduces additional slack resulting from rotation of the trays.

Metal binding compounds and their use in cell culture medium compositions

The present invention is directed generally to metal binding compounds which may be added to cell culture media to replace factors required for cultivation of the cells (e.g. transferrin) which are of animal or human origin. More specifically, the invention is directed to metal binding compounds or complexes thereof comprising one or more transition element cations (such as ferrous or ferric ions), which are added to cell and tissue culture medium compositions. The metal binding compounds may be added to the media alone or may be first complexed with a transition metal ion. The invention is also directed to methods of use of such compositions, including, for example, methods for the cultivation of eukaryotic cells, particularly animal cells, in vitro. The invention also relates to compositions comprising such culture media and one or more cells, and to kits comprising one or more of the above-described compositions. The compositions of the present invention obviate the need for naturally derived metal-binding proteins, such as transferrin and ceruloplasmin, which may contain blood-borne pathogens.

Soybean transgenic event mon87751 and methods for detection and use thereof

La invención proporciona un evento de Glycine max transgénico MON87751, plantas, células vegetales, semillas, partes de plantas, plantas de la progenie y productos básicos que comprenden el evento MON87751. La invención también proporciona polinucleótidos específicos para el evento MON87751, las plantas, las células vegetales, las semillas, las partes de plantas y los productos básicos que comprenden polinucleótidos para el evento MON87751. La invención también proporciona métodos relacionados con el evento MON87751.

Soybean transgenic event mon87751 and methods for detection and use thereof

Benzofuran derivatives

Apparatus and method for managing data storage

An apparatus for controlling a log-structured data storage system, operable with a first log-structured data storage area for storing data, comprises a metadata storage component for controlling the first log-structured data storage area and comprising a second log-structured data storage area for storing metadata; and means for nesting the second log-structured data storage area for storing metadata within the first log-structured data storage area. The apparatus may further comprise at least a third log-structured data storage area for storing further metadata, and means for nesting the at least a third log-structured data storage area within the second log-structured data storage area.

Transaction product with separable pieces

A transaction product includes a substrate and an account identifier. The substrate defines a plurality of pieces separable from a remainder of the substrate. Following separation of the plurality of pieces from the remainder of the substrate, the plurality of pieces are configured to be assembled with one another to define a three-dimensional object. The account identifier is attached to the substrate and links the transaction product to at least one of an account and a record, wherein the account identifier is machine readable by a point-of-sale terminal. Stored-value cards, combinations, methods of facilitating use of a transaction product and other embodiments are also disclosed.

Gas actuated firearm

Ballistic ranging methods and systems for inclined shooting

A portable system for facilitating inclined shooting of projectile weapons comprises a ranging system, an inclinometer and a processor. The ranging system measures a line-of sight range distance from a vantage point to a target that is elevated or depressed relative to the vantage point, and the inclinometer measures an inclination angle of a line of sight between the vantage point and the target. Based on information from the rangefinder and inclinometer, the processor determines a predicted altitude-compensated inclined shooting (ACIS) trajectory at the line-of sight range distance for a preselected projectile. The ACIS trajectory is based on a bullet path height correction between a bullet path height at a first altitude and a bullet path height at a second altitude, a range distance of the target from the vantage point, and selected meteorological atmospheric information.

Anti-cd98 antibodies and antibody drug conjugates

The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

Optical sighting system

An automatic optical sighting system generates at least one adjustment for an adjustable optical system based on at least one detected condition, an appropriate dynamic model of a projectile in flight, and a solution of the equations of motion in flight, so that the projectile will have a trajectory between an origin and a selected target that helps the projectile to hit the target.

Therapeutic fragments of von willebrand factor

An aqueous solution of cysteine-altered von Willebrand Factor fragment which is substantially free of aggregate and capable of therapeutic use for treating thrombosis and a process for preparing such a solution comprising: (A) providing an aqueous solution of the fragment and denaturant; (13) purifying the solution of fragment and denaturant under conditions which promote conversion of aggregated forms of the fragment to the dimeric and/or monomeric forms thereof to provide purified fragment; (C) separating the dissolved; purified fragment from the denaturant while maintaining the aqueous solution of the fragment at a pH of about 2.5 to less than about 5.5 to increase monomerization of, and decrease aggregation of, said purified fragment, thereby forming an aqueous solution of fragment which is substantially free of aggregate.

System and method for access distribution of multiple storage matrixes between multiple host systems

A system is provided for storing data for a plurality of host computers (20) on a plurality of storage arrays so that data on each storage array can be accessed by any host computer. A plurality of adapter cards (22) are used. Each adapter has controller functions for a designated storage array. There is an adapter communication interface (23) (interconnect) between all of the adapters in the system. There is also a host application interface between an application program running in the host computer and an adapter. When a data request is made by an application program to a first adapter through a host application interface for data that is stored in a storage array not primarily controlled by the first adapter, the data request is communicated through the adapter communication interface to the adapter primarily controlling the storage array in which the requested data is stored. <IMAGE>

Paramagnetic boards and attachments

Apparatus for picture processing with resolution conversion

Data manipulation apparatus is described for converting raster-scanned data received from a scanner 2 at a first picture element (pel) resolution to a second lower pel resolution for display on a CRT terminal 4. The apparatus includes a scale-changing means 3 which operates on receipt of the image data from the scanner 2 to perform a scalechange operation on the pels, first in the image row direction and then in the image column direction. The row scale-change operation is performed by scale-change projector 5 which functions to replace subgroups of pels in the input image rows by single pels at its output. The image data emerging from projector 5, consolidated in the row direction, is further processed by a second scale-change projector 6 which performs the column scale-changing operation. Again, the size of the sub-groups are determined by the degree of compression required to convert to the lower pel resolution.

Anti-cd98 antibodies and antibody drug conjugates

The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.