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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 9. Отображено 9.
29-03-2012 дата публикации

DEVICE AND METHOD OF SEPARATING CELLS BY USING MAGNETIC FORCE

Номер: US20120077267A1
Автор: KIM Min-seok S., LEE Hun-joo, LEE Jeong-gun, PARK Jong-myeon, SIM Tae-seok, SONG Mi-jeong
Принадлежит: SAMSUNG ELECTRONICS CO., LTD.

A cell separation device includes a channel or chamber in which a sample flows or moves, the sample including target cells marked with magnetic particles, and non-target cells, and a magnet which generates a magnetic first force in a first direction with respect to the sample within the channel or chamber. The channel or chamber of the cell separation device is applied with a second force in a second direction opposite to the first direction of the magnetic force. According to the cell separation device and a method of separating cells, the target cells move in the first direction by the magnetic force, and the non-target cells move in the second direction by the second force, by simultaneously applying the magnetic force and the second force in opposing directions, thereby separating the target cells from the non-target cells. 1. A cell separation device comprising:a channel having a curved shape in a plan view, and in which a sample flows, the sample comprising target cells marked with magnetic particles, and non-target cells;a sample inlet connected to a first end of the channel;a first sample outlet and a second sample outlet respectively connected to a second end of the channel opposite the first end; anda magnet adjacent to an outer circumference of the channel, wherein the magnet generates a magnetic force with respect to the sample.2. The device of claim 1 , wherein the channel has a circular or oval shape in the plan view.3. The device of claim 1 , wherein the channel has a spiral shape which is a planar curve emanating from a central point claim 1 , and becoming progressively farther away from the central point as the channel revolves around the central point.4. The device of claim 3 , whereinthe sample inlet is connected to the first end of the channel at the central point, andthe first and second sample outlets are connected to the second end of the channel at an outer point of the spiral shape.5. The device of claim 1 , wherein the magnet comprises a ...

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Номер записи: 1
05-03-2015 дата публикации

MICROFLUIDIC APPARATUS

Номер: US20150064774A1
Автор: KIM Min-seok S., MOON Hui-sung, PARK Jong-myeon
Принадлежит: SAMSUNG ELECTRONICS CO., LTD.

A microfluidic apparatus mounted on a rotation driving unit for inducing a fluid to flow due to a centrifugal force includes: a target chamber that houses a first fluid; a first chamber that houses a second fluid and is disposed closer to a rotation center of the microfluidic apparatus in a radius direction than the target chamber, the first chamber being connected to the target chamber by a first channel; a first valve that prevents a flow of the second fluid through the first channel; and a second chamber disposed closer to the rotation center in the radius direction than the target chamber and connected to the target chamber by a second channel, wherein the first fluid is transported to the second chamber by supplying the second fluid to the target chamber by the centrifugal force. 1. A microfluidic apparatus for inducing a fluid to flow due to a centrifugal force , the apparatus comprising:a target chamber that houses a first fluid;a first chamber that houses a second fluid and is disposed closer to a rotation center of the microfluidic apparatus in a radius direction than the target chamber, the first chamber being connected to the target chamber by a first channel;a first valve that controls a flow of the second fluid through the first channel; anda second chamber disposed closer to the rotation center in the radius direction than the target chamber and connected to the target chamber by a second channel,wherein the first fluid is transported from the target chamber to the second chamber by supplying the second fluid to the target chamber from the first chamber by the centrifugal force.2. The microfluidic apparatus of claim 1 , further comprising a second valve that controls the flow of the first fluid through the second channel.3. The microfluidic apparatus of claim 1 , wherein the first fluid and the second fluid do not mix with each other.4. The microfluidic apparatus of claim 1 , wherein the first channel is filled with a gas.5. The microfluidic apparatus ...

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Номер записи: 2
29-05-2014 дата публикации

MICROFLUIDIC APPARATUS AND METHOD OF ENRICHING TARGET CELLS BY USING THE SAME

Номер: US20140147862A1
Автор: KIM Min Seok S., PARK Jong-myeon
Принадлежит:

A microfluidic apparatus capable of being mounted on a rotation driving unit. When mounted on the rotation driving unit and rotated, a fluid flow is induced in the apparatus due to a centrifugal force. the microfluidic apparatus includes a sample supplying unit that comprises a sample chamber to house a sample and provides a fluid including a target material in which fine beads are bound to a target cell in the sample; a density-gradient separation unit that houses a density gradient material with a lower density than the target material, and receives the fluid from the sample supplying unit to separate the target material from the fluid based on a density difference; a fluid supplying channel connecting the sample supplying unit to the density-gradient separation unit to form a passage of the fluid; and a fluid supplying valve provided to the fluid supplying channel to selectively allow a flow of the fluid. 1. A microfluidic apparatus adapted to be mounted on a rotation driving unit and wherein when mounted on the rotation driving unit and rotated about a rotation center of the apparatus , a fluid flow is induced in the apparatus due to a centrifugal force , the microfluidic apparatus comprising:a sample chamber in which a sample fluid is centrifuged,wherein a partition wall is provided in the sample chamber to form a bottleneck portion together with at least one of a top wall and a bottom wall of the sample chamber to partially restrict the flow of the sample fluid in a radial direction of the sample chamber, andwherein a gap between the bottleneck portion and the at least one of the top wall and the bottom wall has a size or dimension that is greater than a size or dimension of a gap that would induce a capillary phenomenon with the sample fluid and which is sufficiently large to allow target cells and fine beads in the sample fluid to move back and forth through the gap during a mixing process whereby the apparatus is rotated back and forth in clockwise and ...

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Номер записи: 3
05-06-2014 дата публикации

MICROFLUIDIC APPARATUS AND METHOD OF ENRICHING TARGET MATERIAL IN BIOLOGICAL SAMPLE BY USING THE SAME

Номер: US20140154664A1
Автор: KIM Min Seok S., PARK Jong-myeon
Принадлежит:

A micro fluidic apparatus includes a sample chamber that divides a sample into a first fluid layer and a second fluid layer due to a centrifugal force; a first enriching unit a that receives the first fluid layer from the sample chamber, forms a first complex of a first fine particle and the first target material, and separates the first complex from the first fluid layer using a density difference; and a second enriching unit that receives the second fluid layer from the sample chamber, forms a second complex of a second fine particle and the second target material, and separates the second complex from the second fluid layer using a density difference. 1. A microfluidic apparatus mounted on a rotation driving unit , the microfluidic apparatus comprising:a sample chamber that receives a biological sample and separates the biological sample into a first fluid layer comprising a first target material and a second fluid layer comprising a second target material using centrifugal force;a first enriching unit that receives the first fluid layer from he sample chamber, forms a first complex of a first fine particle and the first target material, and separates the first complex from the first fluid layer using a density difference with a density-gradient material (DGM) having a lower density than the first complex; anda second enriching unit that receives the second fluid layer from the sample chamber, forms a second complex of a second fine particle and the second target material, and separates the second complex from the second fluid layer using a density difference between the second fluid layer and the second complex.2. The microfluidic apparatus of claim 1 , wherein the first enriching unit comprises:a first particle chamber that houses the first fine particle and is connected to the sample chamber by a first sample channel to receive the first fluid layer from the sample chamber;a separation chamber that houses the DGM and is connected to the first particle chamber ...

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Номер записи: 4
04-12-2014 дата публикации

MICROFLUIDIC APPARATUS

Номер: US20140357466A1
Автор: KIM Min-seok S., MOON Hui-sung, PARK Jong-myeon
Принадлежит: SAMSUNG ELECTRONICS CO., LTD.

A microfluidic apparatus that is mounted on a rotation driver and induces a flow of a fluid according to a centrifugal force includes a lower structure having a microfluidic structure including a recovery chamber for accommodating a target material separated from a sample and a channel for forming an inflow path of the target material to the recovery chamber; an upper plate forming an upper wall of the recovery chamber and the channel; and a lid formed integrally to the upper plate and removable from the upper plate to open at least a part of a top of the recovery chamber. 1. A microfluidic apparatus that induces a flow of a fluid by centrifugal force when rotated , the microfluidic apparatus comprising:a lower structure having a microfluidic structure comprising a recovery chamber for accommodating a target material separated from a sample, and a recovery channel connected to the recovery chamber and providing an inflow path of the target material to the recovery chamber;an upper plate providing an upper wall of the recovery chamber and the channel, wherein the upper plate comprises an integrated first lid that is removable from the upper plate to open at least part the recovery chamber.2. The microfluidic apparatus of claim 1 , wherein the upper plate comprises a removal groove depressed into the upper plate from at least one of a top surface and a bottom surface of the upper plate that defines an edge of the first lid claim 1 , andthe first lid can be separated from the upper plate along the removal groove.3. The microfluidic apparatus of claim 2 , wherein a part of the edge of the first lid is exposed along an outer perimeter of the microfluidic apparatus.4. The microfluidic apparatus of claim 3 , wherein the lower structure comprises a depression in an outer perimeter of the lower structure adjacent to the exposed part of the edge of the first lid claim 3 , the depression extending along a bottom surface of the first lid.5. The microfluidic apparatus of claim 1 ...

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Номер записи: 5
23-08-2016 дата публикации

Microfluidic apparatus with increased recovery rate of target material from a sample

Номер: US9421541B2
Автор: Hui-Sung MOON, Jong-Myeon Park, Min-seok S. KIM
Принадлежит: SAMSUNG ELECTRONICS CO LTD

A microfluidic apparatus that is mounted on a rotation driver and induces a flow of a fluid according to a centrifugal force includes a lower structure having a microfluidic structure including a recovery chamber for accommodating a target material separated from a sample and a channel for forming an inflow path of the target material to the recovery chamber; an upper plate forming an upper wall of the recovery chamber and the channel; and a lid formed integrally to the upper plate and removable from the upper plate to open at least a part of a top of the recovery chamber.

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Номер записи: 6
15-12-2015 дата публикации

Microfluidic apparatus and method of enriching target cells by using the same

Номер: US9211512B2
Автор: Jong-Myeon Park, Min Seok S. KIM
Принадлежит: SAMSUNG ELECTRONICS CO LTD

A microfluidic apparatus capable of being mounted on a rotation driving unit. When mounted on the rotation driving unit and rotated, a fluid flow is induced in the apparatus due to a centrifugal force. the microfluidic apparatus includes a sample supplying unit that comprises a sample chamber to house a sample and provides a fluid including a target material in which fine beads are bound to a target cell in the sample; a density-gradient separation unit that houses a density gradient material with a lower density than the target material, and receives the fluid from the sample supplying unit to separate the target material from the fluid based on a density difference; a fluid supplying channel connecting the sample supplying unit to the density-gradient separation unit to form a passage of the fluid; and a fluid supplying valve provided to the fluid supplying channel to selectively allow a flow of the fluid.

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Номер записи: 7
22-08-2017 дата публикации

Microfluidic apparatus

Номер: US09737889B2
Автор: Hui-Sung MOON, Jong-Myeon Park, Min-seok S. KIM
Принадлежит: SAMSUNG ELECTRONICS CO LTD

A microfluidic apparatus mounted on a rotation driving unit for inducing a fluid to flow due to a centrifugal force includes: a target chamber that houses a first fluid; a first chamber that houses a second fluid and is disposed closer to a rotation center of the microfluidic apparatus in a radius direction than the target chamber, the first chamber being connected to the target chamber by a first channel; a first valve that prevents a flow of the second fluid through the first channel; and a second chamber disposed closer to the rotation center in the radius direction than the target chamber and connected to the target chamber by a second channel, wherein the first fluid is transported to the second chamber by supplying the second fluid to the target chamber by the centrifugal force.

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Номер записи: 8
09-08-2016 дата публикации

Microfluidic apparatus and method of enriching target material in biological sample by using the same

Номер: US09410127B2
Автор: Jong-Myeon Park, Min Seok S Kim
Принадлежит: SAMSUNG ELECTRONICS CO LTD

A micro fluidic apparatus includes a sample chamber that divides a sample into a first fluid layer and a second fluid layer due to a centrifugal force; a first enriching unit a that receives the first fluid layer from the sample chamber, forms a first complex of a first fine particle and the first target material, and separates the first complex from the first fluid layer using a density difference; and a second enriching unit that receives the second fluid layer from the sample chamber, forms a second complex of a second fine particle and the second target material, and separates the second complex from the second fluid layer using a density difference.

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Номер записи: 9