Apparatus Enabling High Density Information Storage in Molecular Chains

A parallelized chain-synthesizing technique includes an array of wells, each well in the array providing a location where a specific arbitrary sequence for polymeric chains can be grown. An optical addressing system selectively delivers light to the wells to mediate or control reactions in the wells. 1. A parallelized chain-synthesizing apparatus , comprising:an array of locations for growing different arbitrary sequences for polymeric chains; andan optical addressing system for selective delivery of light to the locations to mediate or control chemical reactions for the growth of the different sequences at the locations.2. The parallelized chain-synthesis apparatus of claim 1 , wherein the polymeric chains are DNA strands.3. A microfluidic device comprising the chain-synthesis apparatus of .4. A parallelized chain-synthesizing apparatus claim 1 , comprising an array of wells claim 1 , wherein each well provides a location for growing a specific arbitrary sequence for polymeric chains and each well is provided with an optical filter or shutter claim 1 , each optical filter or shutter being configured to independently allow or block radiation from a light source.5. The parallelized chain-synthesizing apparatus of claim 4 , wherein the optical filter or shutter is provided in a filter array.6. The parallelized chain-synthesizing apparatus of claim 5 , wherein light from the light source is polarized and the filter array is a pixilated liquid crystal array.7. A parallelized chain-synthesizing apparatus claim 5 , comprising an array of wells claim 5 , each well providing a location for growing a specific arbitrary sequence for polymeric chains claim 5 , and an array of light emitting diodes claim 5 , wherein a diode in the array of diodes is coupled with a well in the array of wells.8. A parallelized chain-synthesizing apparatus claim 5 , comprising an array of wells claim 5 , each well providing a location for growing a specific arbitrary sequence for polymeric chains ...

System and Method for Diffractive Steering of Electromagnetic Radiation

A light steeling system and method for diffractive steering of electromagnetic radiation such as visible light is disclosed. Embodiments of the light steering system include leaky-mode SAW modulators as light modulator devices. The SAW modulators preferably include reflective diffractive gratings. The gratings are mounted to/patterned upon an exit face that opposes an exit surface of the SAW modulator, in one example. Steering of light signals emitted from the SAW modulators in these systems can be accomplished by varying wavelength of light signals introduced to the SAW modulators, and/or by varying frequency of RF drive signals applied to the SAW modulators. In addition, light field generators that incorporate SAW modulators of the proposed light steering system within displays of the light field generators are also disclosed.

METROLOGY AND PROFILOMETRY USING LIGHT FIELD GENERATOR

A system and method for metrology and profilometry using a light field generator are disclosed. For this purpose, a system such as an optical analysis system scans a sample using light, and detects light reflected off a sample in various ways. The system operates different operational modes including a backscatter intensity, a triangulation, and an interferometric mode. For this purpose, the optical analysis system includes one or more optical angle modulation systems, such as surface acoustic wave (SAW) modulators, that emit light, a sample holder, and a scanning system that scans the one or more SAW modulators relative to the sample holder. The system performs tomographic reconstructions of information generated by the scans to create 3D maps/volume datasets of the sample. 1. An optical analysis system , the system comprising:an optical angle modulation system for scanning light over an object; anda computer system for mapping the object.2. The system of claim 1 , wherein the optical angle modulation system comprises a parallax panoramagram display system such as a lenticular display claim 1 , a parallax barrier display claim 1 , an integral imaging/integral photography display claim 1 , or a directional illumination display.3. The system of claim 1 , wherein the optical angle modulation system comprises one or more acousto optic modulators (AOMs) that emit light.4. The system of claim 1 , wherein the optical angle modulation system comprises one or more surface acoustic wave (SAW) modulators that emit light.5. The system of claim 4 , wherein chirped RF pulses are applied to the SAW modulators to focus the emitted light into spots upon or around a surface of the object.6. The system of claim 1 , further comprising a mechanical scanning system that moves the optical angle modulation system relative to the object.7. The system of claim 6 , wherein the mechanical scanning system includes a rotation stage that carries the object claim 6 , wherein the rotation stage ...

MOLECULAR CHAIN SYNTHESIZER

An apparatus for optically-verified de novo DNA synthesis includes a microfluidic system that has channels leading in and out of a synthesis chamber having a functionalized region on a floor thereof on which a single-strand of DNA to which a nucleotide is to be attached can be fixed. The chamber is in optical communication with both an illumination system, which excites an electron in a fluorophore that is attached to the DNA strand, a detection system, which detects a signature photon emitted as the excited electron decays into its ground state. 1. An apparatus comprising a microfluidic system , a detection system , and an excitation system , wherein said microfluidic system includes a first manufacturing unit , wherein said first manufacturing unit includes a chamber , a first channel , a second channel , and a functionalized region , wherein said functionalized region is configured for holding a molecular chain to which a monomer is to be attached , wherein said functionalized region is disposed in said chamber , wherein said chamber is in optical communication with said detection system , wherein said chamber is in optical communication with said excitation system , wherein said first channel connects to said chamber , wherein said second channel connects to said chamber , wherein said detection system comprises a detector tuned to detect a signature photon from a fluorophore that is attached to said single strand , said single strand having been attached to said functionalized region , and wherein said excitation system comprises a light source disposed for illuminating said fluorophore , said light source being configured to stimulate a specific electronically excited state.2. The apparatus of claim 1 , wherein said microfluidic system is formed on a substrate claim 1 , said apparatus further comprising a second manufacturing unit that has the same structure as said first manufacturing unit claim 1 , wherein said second manufacturing unit is formed on said ...

SAW Modulators with Phase and Angle Selective Optical Coatings

A system and method for improving spatial light modulator (SLM) devices such as Surface Acoustic Wave (SAW) modulators are disclosed. The SAW modulators can improved angular bandwidth and suppress unwanted diffractive orders. In one example, a coating layer(s) is applied to a proximal face of the SAW modulator to improve coupling of guided modes into leaky modes. Additionally, applying coating layers(s) such as a hybrid anti-reflective/highly reflective coating to an exit face of the SAW modulator can suppress transmission of undesired diffractive order(s).

System and method for diffractive steering of electromagnetic radiation

A light steering system and method for diffractive steering of electromagnetic radiation such as visible light is disclosed. Embodiments of the light steering system include leaky-mode SAW modulators as light modulator devices. The SAW modulators preferably include reflective diffractive gratings. The gratings are mounted to/patterned upon an exit face that opposes an exit surface of the SAW modulator, in one example. Steering of light signals emitted from the SAW modulators in these systems can be accomplished by varying wavelength of light signals introduced to the SAW modulators, and/or by varying frequency of RF drive signals applied to the SAW modulators. In addition, light field generators that incorporate SAW modulators of the proposed light steering system within displays of the light field generators are also disclosed.

Tunable spectroscopic source with power stability and method of operation

A laser system for a spectroscopic catheter system utilizes an overmoded cavity ir order to reduce mode hoping induced power fluctuations during wavelength scanning. In the preferred embodiment, a semiconductor gain medium is used to reduce cost. A fiber pigtail is used to define the laser cavity, which has a tight cavity mode spacing of less tha 15 Gigahertz. A diffraction grating is used as the tuning element. A cylindrical lens is used to reduce alignment tolerances and thereby increase manufacturability.

Optical band scanning monitor system and method

A scanning optical monitoring system and method are appropriate for high speed scanning of a WDM signal band. The system and method are able to identify dropped channels or, more generally, discrepancies between the determined or detected channel inventory and a perpetual inventory for the WDM signal, which perpetual inventory specifies the channels that should be present in the WDM signal assuming proper operation of the network. The system includes a tunable optical filter that scans a pass band across a signal band of a WDM signal to generate a filtered signal. A photodetector then generates an electrical signal in response to this filtered signal. A decision circuit compares the electrical signal to a threshold and a controller, which is responsive to the decision circuit, inventories the channels in the WDM signal.

System and process for post alignment polarization extinction ratio compensation in semiconductor laser system

A system and process for tuning the polarisation extinction ratio (PER) of an optoelectronic system during and/or after its manufacture includes fixtures (104) that allow for the axial rotation of the polarization-maintaining optical fiber (106) relative to the optical system after the optical fiber has been installed in the system. This allows compensation due to the degradation in the PER ratio of the optical systems that results from mechanical stresses placed on the fiber (106) during the manufacture of the systems or misalignment between the fiber (106) and chip axes.

Spectroscopic catheter system with power stable tunable light source

Side firing fiber optic array probe

A multi fiber optic medical probe comprises at least two optical fibers. There are side-firing terminations for the at least two optical fibers. Further, beam-shaping apertures are provided for controlling light propagating between the side-firing terminations and a region lateral to the probe. The provision of the at least two optical fibers allows for multiple optical signals to be transmitted to and/or from the target area within the patient. The side-firing terminations allow for the interrogation of regions that are adjacent to the probe, i.e., extending in a direction parallel to the insertion direction or longitudinal axis of the probe. The beam shaping apertures are provided for controlling light propagating between the side-firing terminations and the region lateral to the probe, in order to control the shape of the emitted beam and also, the direction from which light is collected.

System and method for assessing a quality of a catheter connection using return loss

A system for assessing the quality of the optical connection between a catheter and a console is described that avoids the necessity of a calibration port, although one can still be provided if desired. It operates by monitoring the level of light returning from the catheter head and specifically the degree to which this returning light is attenuated. Reflections will arise at the catheter head's optical window due to the discontinuity between the refractive index of the window and that of air or other medium into which the head is inserted. Since the refractive index of the optical window is known and with the head in a known medium such as air, the level of reflection is known. This enables a controller in the console to calculate the round trip loss and thus monitor the loss in the catheter-console interface.

Spektroskopisches kathetersystem mit breit abstimmbarer quelle

Integrated optical system monitoring system

Multi-filter cavity optical channel monitoring system

Optical channel monitoring system with self-calibration

An optical monitoring system provides for out-of-band calibration. As a result, calibration can be performed simultaneously with monitoring. This can be used to accomplish faster and/or more accurate scanning. In addition, the need for complex switching and/or multiplexing capabilities can be avoided. The system comprises a signal source of an optical signal having spectrally separated channels, which are distributed within a spectral band, such as a WDM signal. A reference source generates a reference signal outside of the spectral band. A tunable filter filters the optical signal and the reference signal. A reference signal detector then detects the filtered reference signal, while an optical signal detector detects the filtered optical signal.

Spectroscopic catheter system with widely tunable source and method of operation

A laser system for a spectroscopic catheter system uses multiple semiconductor gain media having gain peaks at different wavelengths. The output from the gain media is preferably coupled into single-mode fiber using conventional opto-electronic packaging techniques. As a result, the laser oscillator source has a spectral output that is wider than the gain bandwidth of a single medium to enable it to access the entire spectrum of interest, which is presently in the near infrared. Moreover, the semiconductor gain media can be packaged in a stable and controlled environment for long-term performance.

Multi-filter cavity optical channel monitoring system

Multi-filter cavity optical channel monitoring system

A channel monitoring system has improved the spectral filtering accuracy by using a tunable filter system that transmits the optical signal through serial filter cavities. This has the effect of dramatically narrowing the filter's transfer function. Moreover, it improves side mode rejection. In the preferred embodiment, the filter is implemented in a double-pass configuration.

Optical channel monitoring system with self-calibration