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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 21. Отображено 21.
08-09-2010 дата публикации

Method for measuring content of components of prince's-feather herb

Номер: CN0101822723A
Принадлежит:

The invention provides a method for measuring content of components of prince's-feather herb and belongs to the technical field of medicament content measurement. High performance liquid chromatography is adopted to measure the content of eight compounds, namely catechin, homo-orientin, orientin, quercetin-3-O-(2'-O-alpha-rhamnose)-betal-glucal, texifolin, luteolin-7-O-beta-D-glucoside, quercetin and kaempferide-3-0-beta-3-D-glucoside, in the prince's-feather herb under the same chromatographic condition. Compared with the conventional single component content measuring method, the method of the invention is more integral, characteristic and stable, and provides test basis for further improving the quality of the prince's-feather herb and the re-development and application of the prince's-feather herb. The invention also provides the methods for preparing reference solution and test sample solution.

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12-08-2009 дата публикации

Method for measuring content of Bletilla striata medicinal materials

Номер: CN0101502616A
Принадлежит:

The invention discloses a method for measuring the content of common bletilla pseudobulb medical materials. The method adopts bis(4-(Beta-D-pyranoglucose oxygen) benzyl)-2-isobutylmalate as a comparison product and uses high performance liquid chromatography to measure the content of the bis(4-(Beta-D-pyranoglucose oxygen) benzyl)-2-isobutylmalate of the common bletilla pseudobulb medical materials. The method is convenient, fast and accurate and provides good standard for controlling the quality of the common bletilla pseudobulb medical materials.

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26-03-2014 дата публикации

Preparation method for effective components of buxus sinica varparvifolia and application of effective components

Номер: CN103655648A
Принадлежит:

The invention relates to a preparation method for effective components of buxus sinica varparvifolia and application of the effective components and belongs to the field of extraction of the effective components of traditional Chinese medicines. The preparation method comprises the following steps of a, extracting the buxus sinica varparvifolia through 0-95% ethanol water to obtain an extracting solution; b, recycling a solvent in the extracting solution until the alcohol taste disappears to obtain a buxus sinica varparvifolia aqueous solution or extract, then acidifying the buxus sinica varparvifolia aqueous solution or extract through acidic water until the pH of the acidified aqueous solution is 1-6, extracting the aqueous solution through ethyl acetate to obtain a water part obtained by extraction of the ethyl acetate; C, alkalizing the water part through alkaline until the pH of the alkalized solution is 8-14, extracting the alkalized solution through chloroform, and concentrating ...

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26-01-2011 дата публикации

Method for quickly screening and identifying compound with specific structure by combination of liquid chromatogram and tandem mass spectrum

Номер: CN0101957351A
Принадлежит:

The invention relates to a method for screening a compound with certain specific structure (such as certain pharmacophore) from Chinese medicinal herbs by using the combination of a liquid chromatogram, fragment targeting multi-reaction monitoring and a tandem mass spectrum, and performing structural resolution on the screened compound. The method comprises the following steps of: performing first-level mass spectrum scanning on a Chinese medicinal herb crude extract to obtain molecular weight information and quasi-molecule ions of the compound in the crude extract; under the condition that a daughter ion (D1) corresponding to certain specific structural fragment is ensured to be generated by intra-source CID and a daughter ion (D2) of the D1 can be obtained through a second-level mass spectrum, selecting the D1 which is more than D2 as an ion channel of the multi-reaction monitoring, and screening the compound with the specific structure; and aiming at the quasi-molecule ions of the screened ...

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17-06-2015 дата публикации

Fluorescent activity detection method for human-derived silent information regulator 5

Номер: CN104714024A
Принадлежит:

The invention discloses a fluorescent activity screening method for the human-derived silent information regulator 5 (Sirtuin 5). According to the invention, polypeptide containing a fluorescence group and a fluorescence quenching group and having a succinylation modified group is used as a substrate; fluorescence intensity is correlated with the enzymatic activity of Sirtuin 5; and FRET effect may allow a Sirtuin 5 recognition site, i.e., the substrate succinylated lysine, to be located at the central part of the substrate, and thus, the substrate polypeptide is more similar to a natural substrate of Sirtuin 5 and bonding is tighter. More options for the fluorescence group can be provided so as to obtain more reliable screening results. The method is applicable to screening of Sirtuin 5 regulator or activity detection of Sirtuin 5 in biological samples, has the characteristics of micromation, automation, rapidness, reliability and the like and is suitable for high flux application.

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04-05-2011 дата публикации

Method for sieving active ingredients playing protection role in cranial nerve from erigeron breviscapus

Номер: CN0102043020A
Принадлежит:

The invention relates to a sieving method of active ingredients of a traditional Chinese medicine, in particular provides a method for sieving active ingredients playing a protection role in cranial nerve from erigeron breviscapus. The method comprises the following steps of: dividing an erigeron breviscapus extract into components with different polarities by adopting a modern separation technology; forming a composition from the components according to different proportions; carrying out finger-print analysis and nerve cell damaged model protection role test on the composition, carrying out statistical treatment on finger-print chemical information and pharmacological activity information data, and sieving active ingredients and active components in erigeron breviscapus by utilizing finger-print pharmacology correlation research. The method can be used for rapidly, simply, conveniently and accurately sieving active ingredients playing protection role in cranial nerve from erigeron breviscapus ...

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21-01-2015 дата публикации

Chewable tablets capable of reinforcing earth to generate metal and preparation method thereof

Номер: CN104286839A
Принадлежит:

The invention discloses chewable tablets capable of reinforcing earth to generate metal and a preparation method thereof. The chewable tablets mainly comprise the following components in parts by weight: hawthorn 20-30, malt 10-20, dried tangerine peel 5-10, poria cocos 5-10, Semen Raphani 3-8, Singli Roxbrugh Rose fruit powder 10-15, dextrin 4-8, citric acid 2-5 and sucrose 5-10. The chewable tablets are good in taste, and can be used as snack foods, and when the tablets are eaten, the tablets can play the role of eliminating stagnated food and promoting digestion, clearing away the heat and eliminating phlegm, treating constipation, invigorating the spleen and tranquilizing the mind.

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25-05-2011 дата публикации

Purine derivatives for treating hepatitis B and preparation method and application thereof

Номер: CN0102070670A
Принадлежит:

The invention relates to the field of pharmaceutical chemistry, in particular to purine compounds capable of treating hepatitis B and having a structure shown in a structural general formula I, and pharmacologically acceptable inorganic or organic acid salts thereof, and a preparation method and application thereof. Pharmacological tests prove that: the compounds have obvious activity of resisting hepatitis B virus and can be applied to preparing anti-virus medicines.

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04-05-2011 дата публикации

Quality control method for erigeron breviscapus (Vant.) hand-mazz.

Номер: CN0102038728A
Принадлежит:

The invention relates to the field of the quality control on traditional Chinese medicine, specifically to a quality control method for erigeron breviscapus(Vant.) hand-mazz. The method comprises a fingerprint detection method and a multiple-indicative content detection method for erigeron breviscapus (Vant.) hand-mazz, wherein the fingerprint detection method employs UPLC detection method, through which 24 characteristic peaks are found and 8 characteristic peaks are ascribed. By using content detection method for erigeron breviscapus(Vant.) hand-mazz., the UPLC-PDA method, contents of following constituents are determined: erigeroside, chlorogenic acid, breviscpini glycoside, Scutellarin, 3,4-0-dicaffeoylquinic acid, 3,5-0-dicaffeoylquinic acid and 4,5-0-dicaffeoylquinic acid. Compared with the prior art, the fingerprint detection method and the multiple-indicative content detection method for erigeron breviscapus (Vant.) hand-mazz are improved in the invention, so that the quality of ...

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22-12-2004 дата публикации

治疗咽炎的中药制剂及其制作方法

Номер: CN0001555840A
Принадлежит:

A Chinese medicine for treating pharyngolaryngitis, pharyngalgia, and tonsillitis is prepared from 4 Chinese-medicinal materials including liquorice root, scutellaria root, borneol, etc through extracting, refining and purifying.

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27-10-2010 дата публикации

Scutellarin aglycone derivative for treating vascular dementia and preparation method and application thereof

Номер: CN0101870684A
Принадлежит:

The invention relates to the field of pharmaceutical chemistry, in particular to a scutellarin aglycone derivative which can treat vascular dementia and has structures shown in the following structural formulas I and II, and pharmacologically acceptable inorganic or organic acid salt, a preparation method and application thereof. A pharmacological test proves that the scutellarin aglycone derivative has obvious activity of resisting nerve cell damage caused by induction of hydrogen peroxide and can be used for the application in the preparation of a medicament for resisting vascular dementia.

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25-04-2012 дата публикации

Method for measuring content of ellagic acid ingredients in euscaphis japonica medicinal materials

Номер: CN0101788537B
Принадлежит:

The invention provides a method for measuring content of ellagic acid ingredients in euscaphis japonica medicinal materials, which synchronously measures the contents of at least two of five ingredients of ellagic acid, 3,3'-dimethoxy ellagic acid, 3,3'-dimethoxy ellagic acid-4'-O-beta-D-xyloside, 3,3'-dimethoxy ellagic acid-4'-O-beta-D-glucoside and 3,3'-dimethoxy ellagic acid-4'-O-alpha-D-arabinoside contained in the euscaphis japonica medicinal materials by using a high efficiency liquid chromatography or an ultra-high efficiency liquid chromatography under the same chromatogram condition.In the invention, the contents of the multiple ingredients in the euscaphis japonica medicinal materials are measured under the same chromatogram condition so that the method for measuring the content of the ellagic acid ingredient in the euscaphis japonica medicinal materials has better integrity, characteristics and stability as well as high precision, favorable repeatability and high recovery rate ...

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26-03-2014 дата публикации

Dexketoprofen trometamol quick-release/sustained-release double-layer tablet and preparation method thereof

Номер: CN103655504A
Принадлежит:

The invention relates to a dexketoprofen trometamol quick-release/sustained-release double-layer tablet and a preparation method thereof, and provides a simple and convenient preparation process method for pressing the double-layer tablet consisting of a quick-release layer and a sustained-release layer, wherein the quick-release layer mainly comprises dexketoprofen trometamol, a sustained-release, a diluent, a binding agent and a lubricant. According to the dexketoprofen trometamol quick-release/sustained-release double-layer tablet provided by the invention, due to release of the quick-release part, the medicine is enabled to rapidly achieve effective blood concentration, the sustained-release part can be released slowly, and the effect that the dexketoprofen trometamol can be continuously released for 12 hours when being taken once is achieved. The defects that the conventional dexketoprofen trometamol preparation needs to be taken for multiple times in clinical treatment, and the blood ...

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16-06-2010 дата публикации

Method for preparing total flavonoids, total tannins and galic acid compounds of polygonum capitatum

Номер: CN0101732421A
Принадлежит:

The invention relates to a method for preparing total flavonoids, total tannins and galic acid compounds of polygonum capitatum. The method comprises the following steps: quenching polygonum capitatum by 40 to 80 percent ethanol (methanol or acetone) or coating refluxed extract on D101 macroporous resin, eluting the polygonum capitatum by 70 to 85 percent ethanol (or methanol), coating concentrated eluant on an MCI column, eluting the MCI column by water, performing water solution and alcohol precipitation after concentrating the eluant, and obtaining the galic acid compounds when concentrating supernatant liquid to extractum; eluting the galic acid compounds by 80 percent ethanol (or 85 percent methanol), concentrating the eluant to extractum, after dissolving the extractum by 95 percent ethanol, coating the solution on a SephadexLH-20 gel column, eluting the gel column by 95 percent ethanol to colorlessness, and obtaining the total flavonoids when concentrating the eluant to extractum ...

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13-01-2010 дата публикации

Chinese medicine preparation for preventing upper respiratory tract infection and preparing method thereof

Номер: CN0100579539C
Принадлежит:

The present invention discloses a Chinese medicine preparation for curing upper respiratory tract infection and its preparation method. It is made up by using (by weight portion) 3-5 portions of inula cappa, 1-2 portions of andrographis and 2-4 portions of gypsum through a certain preparation process.

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18-02-2015 дата публикации

Active fluorescence detection method of anthropogenic silent information regulatory factor 6 (Sirtuin6)

Номер: CN104359883A
Принадлежит:

The invention discloses an active fluorescence detection method of an anthropogenic silent information regulatory factor 6 (Sirtuin6). A polypeptide containing fluorophore and quenching group (FRET (fluorescence resonance energy transfer) effect) and long-chain fatty acylation lysine residue is used as a substrate, the fluorescence intensity is associated with the enzymatic activity of Sirtuin6, and the Sirtuin6 recognition site (long-chain fatty acylation lysine) of the substrate is located in the middle of the substrate by the FRET effect, thus, the substrate (polypeptide) is close to a natural substrate of Sirtuin6, and the combination is close; more fluorophores can be selected, and reliable screening result can be obtained. The method can be applied to screening of the Sirtuin6 regulator or is used for active detection of Sirtuin6 in a biological sample, has the characteristics of miniaturization, automation, reliability, rapidness and the like, is suitable for high-reflux application ...

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23-04-2014 дата публикации

Carbamate derivates of scutellarin and seutellarein, and application thereof

Номер: CN103739642A
Принадлежит:

The invention discloses flavonoid compounds which can treat neurodegenerative disease and have the structures represented by the following structure general formula I, II and III, and preparation methods and an application thereof. Physicochemical properties and in-vitro metabolism experiments prove that the compounds have better physicochemical and metabolic properties compared with scutellarin and seutellarein, and can be applied in preparation of drugs for treating the neurodegenerative disease.

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04-06-2014 дата публикации

Preparation method and application of effective component of herba kalimeridis

Номер: CN103830302A
Принадлежит:

The invention relates to a preparation method and application of an effective component of herba kalimeridis, and belongs to the field of traditional Chinese medicine effective component extraction. The preparation method comprises the following steps: a, extracting herba kalimeridis with a ethanol aqueous solution with the mass concentration of 0-95 percent to obtain an extract; b, concentrating the extract until no alcohol smell exists to obtain a herba kalimeridis concentrate; and c, feeding the herba kalimeridis concentrate in macroporous resin for adsorption, eluting with water until effluent does not have reducing sugar in detection, eluting with an ethanol aqueous solution with the mass concentration of 40-95 percent, collecting eluent, concentrating, and drying to obtain the effective component of herba kalimeridis. The preparation method and the application have the beneficial effects that the effective component of herba kalimeridis used for preparing a medicine for treating inflammations ...

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26-05-2010 дата публикации

Formula of traditional Chinese medicines for treating soft tissue injury and method for preparing preparation thereof

Номер: CN0101711835A
Принадлежит:

The invention discloses a formula of traditional Chinese medicines for treating soft tissue injury and a method for preparing a preparation thereof. The formula comprises the following six traditional Chinese medicines in parts by weight according to mixture ratio: 3-9 parts of ceratostigma willmottianum, 1-5 parts of hyacinth bletilla, 1-5 parts of Gaultheria yunnanensis, 0.1-0.5 part of dragon's blood, 0.5-2 parts of turpentine and 0.3-2 parts of borneol which are prepared into an externally-applied traditional Chinese medicine preparation. The prepared externally-applied traditional Chinese medicine preparation is a spraying agent, a tincture, a liniment or a film coating agent. The result of experiments shows that the invention has the advantages of no irritability, no hypersensitivity, quick acting of the medicines, obvious effects of promoting the restoration of the injured soft tissues, resisting inflammation and relieving pain and the like. The preparation prepared by the invention ...

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16-03-2011 дата публикации

Method for measuring content of Bletilla striata medicinal materials

Номер: CN0101502616B
Принадлежит:

The invention discloses a method for measuring the content of common bletilla pseudobulb medical materials. The method adopts bis(4-(Beta-D-pyranoglucose oxygen) benzyl)-2-isobutylmalate as a comparison product and uses high performance liquid chromatography to measure the content of the bis(4-(Beta-D-pyranoglucose oxygen) benzyl)-2-isobutylmalate of the common bletilla pseudobulb medical materials. The method is convenient, fast and accurate and provides good standard for controlling the quality of the common bletilla pseudobulb medical materials.

Подробнее
28-07-2010 дата публикации

Method for measuring content of ellagic acid ingredients in euscaphis japonica medicinal materials

Номер: CN0101788537A
Принадлежит:

The invention provides a method for measuring content of ellagic acid ingredients in euscaphis japonica medicinal materials, which synchronously measures the contents of at least two of five ingredients of ellagic acid, 3,3'-dimethoxy ellagic acid, 3,3'-dimethoxy ellagic acid-4'-O-beta-D-xyloside, 3,3'-dimethoxy ellagic acid-4'-O-beta-D-glucoside and 3,3'-dimethoxy ellagic acid-4'-O-alpha-D-arabinoside contained in the euscaphis japonica medicinal materials by using a high efficiency liquid chromatography or an ultra-high efficiency liquid chromatography under the same chromatogram condition. In the invention, the contents of the multiple ingredients in the euscaphis japonica medicinal materials are measured under the same chromatogram condition so that the method for measuring the content of the ellagic acid ingredient in the euscaphis japonica medicinal materials has better integrity, characteristics and stability as well as high precision, favorable repeatability and high recovery rate ...

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