AN ACTIVATION DEVICE TRAP GAS EVACUATED GLASS

HEAD OF A TRIMMER

ROTARY DEVICE WITH TRIPOD

L'invention concerne un dispositif rotatif à monopode, comprenant une tige principale (1), une plate-forme d'adaptation (2) destinée à fixer un équipement photographique, et un dispositif rotatif connectant avec possibilité de rotation la plate-forme d'adaptation (2) à la tige principale (1), caractérisé en ce que ledit dispositif rotatif comprend un tube rotatif (3), emboîté autour de ladite tige principale (1), une première structure de connexion, connectant de manière fixe ladite plate-forme d'adaptation (2) à une extrémité supérieure dudit tube rotatif (3), une deuxième structure de connexion, connectée de manière fixe à une extrémité supérieure de ladite tige principale (1), et une structure de connexion de rotation, disposée entre ladite première structure de connexion et ladite deuxième structure de connexion, de sorte que ladite première structure de connexion et ladite deuxième structure de connexion soient connectées l'une à l'autre avec possibilité de rotation relative.

PROCESS OF DIRECTIONAL ELECTROMAGNETIC RESISTIVITY

NEW DERIVATIVES OF BENZOTHIOPHENE, PRESENTING AN INHIBITING ACTIVITY OF THE TNAP

PROCESS AND DEVICE Of INSPECTION OF LIQUID PRODUCTS

Sont décrits un procédé et un dispositif d'inspection de sécurité de produits liquides avec imagerie par tomodensitométrie double énergie. Le procédé comprend les étapes consistant à obtenir une ou plusieurs images de tomodensitométrie incluant des attributs physiques du produit liquide à inspecter par balayage par tomodensitométrie et un procédé de reconstruction double énergie ; acquérir les attributs physiques de chaque produit liquide à partir de l'image de tomodensitométrie ; et déterminer si le produit liquide inspecté est dangereux en se basant sur les attributs physiques. Le balayage par tomodensitométrie peut être mis en oeuvre par une technique de balayage par tomodensitométrie normale, ou une technique de balayage par tomodensitométrie en spirale. Dans la technique de balayage par tomodensitométrie normale, on peut fixer à l'avance la position de balayage ou elle peut être déterminée par l'opérateur avec une image de radiographie numérique ou déterminée par une analyse automatique ...

MEMBRANES OF PVDF HAS SURFACE SUPERHYDROPHOBE

La présente invention se rapporte au domaine des surfaces solides hydrophobes, et plus particulièrement aux membranes de polyfluorure de vinylidène (PVDF) à surface superhydrophobe. L'invention concerne également le procédé de préparation de ces membranes ainsi que leurs applications industrielles. Les membranes de PVDF selon l'invention comprennent une surface superhydrophobe comprenant une structure rugueuse à l'échelle nanométrique et des nodules cristallins interconnectés.

ROTOR OF REVOLVING ELECTRIC MACHINE AND REVOLVING ELECTRIC MACHINE INCLUDING/UNDERSTANDING SUCH A ROTOR

Le rotor (1) selon l'invention comprend une pluralité de pôles Nord (N) et pôles Sud (S) alternés et formés à partir d'une pluralité d'aimants permanents (3) agencés dans des premiers évidements (4). Ces premiers évidements sont répartis régulièrement autour d'un axe (5) du rotor et se prolongent axialement dans une masse magnétique (2) de celui-ci de manière à définir un nombre prédéterminé de sections polaires (9) circonférentielles. Ces sections polaires comportent des deuxièmes évidements (12) agencés entre les aimants permanents et se prolongent axialement dans la masse magnétique de manière à définir une pluralité de ponts magnétiques (14, 15) présentant une pluralité de hauteurs (htri) dans une partie circonférentielle (11) du rotor. Conformément à l'invention, une première hauteur (htr1) et une deuxième hauteur (htr2) de deux dits ponts magnétiques (14, 15) consécutifs sont différentes.

APPLICATION OF CUSTOMER SERVICE FOR A PORTABLE ELECTRONIC DEVICE

Une application Service Client résidant sur un dispositif électronique portable d'un utilisateur set à obtenir des informations concernant un service offert par un magasin et à demander le service. Cette application peut vérifier les magasins à proximité lors de son démarrage . Une fois que l'utilisateur est considéré comme se trouvant dans la zone de service du magasin (502), le serveur informatique hôte du magasin peut commencer à envoyer des informations concernant différents produits , services, événements ou ateliers proposés par le magasin (510). L'utilisateur peut utiliser l'application pour demander de l'aide sur un produit ou un service auprès d'employés du magasin, pour s'enregistrer à un événement/atelier, pour réserver un produit à retirer , etc.

FILM-FORMING COMPOSITIONS COMPRISING SYNTHETIC LAYERED SILICATE

Massage chair for use in office, has electric current adapter and manual controller installed on base, where inner massage device is connected to current adapter and controller and is fixed on inner frame of backrest by self-tapping screw

La demande concerne un siège de massage comprenant un dossier (1), une assise (6) avec un revêtement souple et un dispositif de réglage de hauteur en-dessous de l'assise (6). La partie inférieure du dispositif de réglage de hauteur est connectée à un piétement (11) avec des roulettes (14). Le dossier (1) est équipé d'un cadre intérieur sur lequel est fixé un dispositif de massage intérieur (3), et un adaptateur de courant électrique (12) et un contrôleur manuel (2) sont installés sur l'assise (6), le dispositif de massage interne (3) étant relié à l'adaptateur de courant (12) et le contrôleur manuel (2).

Doll-shaped charger for charging rechargeable battery for power supply of e.g. smartphone for outdoor use, has conducting part including terminal connected to negative pole, and another terminal mounted on seat and corresponding to chamber

La présente invention fournit un chargeur en forme de poupée compact et portable avec une apparence amusante, en particulier pour une utilisation en extérieur. Il a les caractéristiques suivantes ; une conformation d'apparence intéressante et spécifique, un corps de poupée (1) comprenant un espace de réception principal (10) et un espace de réception secondaire (20), une prise de recharge (2) située dans l'espace de réception principal (10) et à travers la surface du corps de poupée (1) pour le branchement d'une ligne d'alimentation d'un dispositif électronique portable, un boîtier (3) de batteries modulaire situé dans l'espace secondaire de réception (20) et reliée électriquement à la prise de recharge (2) et une carte à circuit imprimé (4), électriquement connectée à la prise de recharge (2) et apte à délivrer la puissance électrique de la batterie à un dispositif électronique portable.

PROCESS AND DEVICE OF MEASUREMENT Of an INTERFACIAL OR SURFACE TENSION BY PENETROMETRIE Of an INTERFACE BETWEEN TWO FLUIDS.

Electrical energy storage system i.e. battery, characterization device, has power channel, and commutation unit connected to storage system to impose exchange of current entering device and storage system connected to channel

Dispositif de caractérisation (10, 20) de systèmes de stockage d'énergie électrique (B1, Bn), agencé pour être connecté simultanément aux systèmes de stockage d'énergie électrique (B1, Bn), pour effectuer la mesure d'au moins une caractéristique pendant un échange de courant électrique, caractérisé en ce que le dispositif de caractérisation (10, 20) comprend : - une seule voie de puissance agencée pour échanger du courant électrique avec les systèmes de stockage d'énergie électrique (B1, Bn), et - des moyens de commutation (41, 4n) agencés pour connecter un des systèmes de stockage d'énergie électrique (B1, Bn) à la voie de puissance tout en en déconnectant les autres systèmes de stockage d'énergie électrique (B1, Bn).

APPARATUS FOR ASEPTICALLY FILLING FOR A FACE MASK AND PREPARATION METHOD FOR FACIAL MASK

La présente description appartient au domaine technique des cosmétiques, concerne plus spécifiquement un appareil de remplissage aseptique (stérile) pour un masque facial et un procédé de préparation de masque facial. L'appareil de remplissage aseptique pour un masque facial comprend une enceinte de séchage à haute température, une cuve de stérilisation à haute pression et à haute température (1), un tube de distribution (2) capable d'être stérilisé à la vapeur à haute température, une machine de remplissage (3) capable d'être stérilisée à la vapeur à haute température, et un atelier de remplissage ayant une propreté de classe cent. Cet appareil peut parfaitement stériliser les masques faciaux, c'est-à-dire garantir que les masques faciaux sont aseptiques sans ajout de conservateurs aux masques faciaux.

SCREEN LED REDUCED SPACING

Un écran à DEL à espacement réduit, comprenant un boîtier de fond (1), un panneau concentrateur (HUB) (2) agencé d'un côté du boîtier de fond (1) et des petits modules agencés de l'autre côté qui sont reliés électriquement au panneau concentrateur (2), est fourni. Le petit module comprend un corps principal de module et une unité de commande de pilotage qui est reliée de manière électrique au corps principal du module pour piloter et commander le corps principal du module. Une plaque adaptatrice (4) est également agencée entre le petit module et le panneau concentrateur (2). Le panneau concentrateur (2) est relié électriquement à la plaque adaptatrice (4). L'unité de commande de pilotage est agencée sur la plaque adaptatrice (4). L'écran à DEL possède l'espacement le plus petit possible et le taux de rejet du petit module est considérablement réduit.

DETECTING ENGINE HAS DOUBLE NETWORK FOR IMAGERY BY RADIATION

La présente invention propose un module détecteur à double réseau adapté à l'imagerie par rayonnement, comprenant un premier réseau de détecteurs (1a) consistant en une pluralité de premiers détecteurs et agencé sur une première surface d'une plaque métallique lourde (5), un deuxième réseau de détecteurs (1b) consistant en une pluralité de deuxièmes détecteurs et agencé sur une deuxième surface de la plaque métallique lourde, la deuxième surface étant opposée à la première surface, et un cadre support, dans lequel le premier réseau de détecteurs et le deuxième réseau de détecteurs agencés respectivement sur les première et deuxième surfaces de la plaque métallique lourde sont montés dans le cadre support. Ce module détecteur à double réseau est de structure simple, et est pratique à assembler et à entretenir, ce qui permet un grand bénéfice économique.

CONNECTION ELEMENT, THE CONNECTION ASSEMBLY, MODULE SUPPORT ASSEMBLY OF BATTERY AND BATTERY MODULE

AUTOMATIC POWER PLANT INTEGRATED IN A SOUND-PROOF BOX TIGHT SAND

PUMP CONTROL ELEMENT

L'invention porte sur une pompe (1) comprenant un élément de régulation de pression d'un fluide la traversant, une pression du fluide en sortie de la pompe (1) étant régulée par une action de l'élément de régulation, l'élément de régulation comprenant deux ressorts (2, 2a) dont un ressort intérieur (2a) entouré par un ressort extérieur (2), telle que l'élément de régulation comprend un bloc de support commun pour les deux ressorts (2, 2a) comprenant deux échelons de différentes hauteurs, chaque échelon supportant un ressort (2, 2a) respectif.

VERFAHREN ZUR ÜBERTRAGUNG VON INFORMATIONEN IN EINEM KOMMUNIKATIONSSYSTEM UNTER VERWENDUNG EINES PFADES

APPARATUS FOR THE COLLECTION AND TREATMENT OF GREY WATER AND WASHING METHOD

LIQUID CRYSTAL DISPLAY PANEL

SYSTEM OF TREATMENT OF WOUND BY PRESSURE NEGATIVE AND PROCEEDED OF ORDER HAS FEEDBACK FOR THIS ONE

L'invention porte sur un système de traitement de plaie par pression négative qui crée un environnement de pression négative dans l'ouverture (511) d'une unité pansement (50) et un environnement de pression positive dans le sac de collecte. Ensuite, une procédure de détection de pression positive est conduite dans l'environnement de pression positive et une procédure de détection de pression négative est conduite dans l'environnement de pression négative. Les résultats de détection sont envoyés pour déterminer si une micro-pompe (31) doit être arrêtée. A negative pressure wound treatment system creates a negative pressure environment in the opening (511) of a dressing unit (50) and a positive pressure environment in the collection bag. Next, a positive pressure detection procedure is conducted in the positive pressure environment and a negative pressure detection procedure is conducted in the negative pressure environment. The detection results are sent to determine if a micro-pump (31) should be stopped.

SYNCHRONOUS REVOLVING ELECTRIC MACHINE WITH ROTOR HAS DOUBLE EXCITATION

HYDRAULIC DAMPER

METHOD FOR CONTROLLING A SYNCHRONOUS ROTARY ELECTRICAL MACHINE WITH DOUBLE EXCITATION AND CORRESPONDING ROTARY ELECTRIC MACHINE

HAMMER ELECTRIC MULTIFUNCTION SWITCHABLE BETWEEN DIFFERENT OPERATION MODES

Ce marteau présente un boîtier, un cylindre tournant (10), un marteau percuteur incorporé dans le cylindre (10), un module de percussion, un module de rotation pour l'entraînement du cylindre tournant (10), un moteur électrique (1), une roue dentée (18) pour la sortie d'énergie, la roue dentée (18) étant engrenée simultanément avec deux groupes de roues dentées d'entraînement (4) montés séparés l'un de l'autre et étant couplés respectivement avec le module de percussion ou le module de rotation. Un dispositif de couplage est disposé entre le module de percussion, le module de rotation et les roues dentées d'entraînement (4), un mécanisme de commutation (2) étant monté sur le marteau électrique, et un ressort de rappel étant disposé entre le module de percussion et le module de rotation.

Connection structure for connecting batteries used in e.g. portable radio apparatus, has hook ring forming part allowing fixation of end of conducting part between round lid and negative electrode by being in contact with negative electrode

Cette structure est caractérisée en ce qu'elle comprend les caractéristiques suivantes : un corps (1), comprenant un couvercle arrondi (11) auquel sont fixées des parois de support (12) ; un fond (2) destiné à être fixé à l'autre extrémité des parois de support (12) de manière à définir un premier, un deuxième et un troisième espaces de réception de piles (10, 20, 30) ; une anode (3) et une électrode négative (4), disposées sur le couvercle arrondi (11) ; des pièces conductrices reliant les espaces de réception (10, 20, 30).

PROCEEDED Of INSPECTION OF SAFETY OF LOADING BASES ON a SWEEPING IN SPIRAL.

Static interrupting device.

PROCESS Of ADMINISTRATION Of an OPEN COMPUTING SYSTEM

AUXILIARY MANUAL BRAKE SYSTEM OF VEHICLE

CHEMICO-MECANICAL COMPOSITION OF POLISHING, EXEMPTS CELLULOSE WATER-SOLUBLE, CONCENTRABLE, STABLE

Une composition de polissage chimico-mécanique utile pour polissage chimico-mécanique d'une plaquette de semiconducteurs contenant un métal d'interconnexion, est fournie, comprenant, en tant que composants initiaux : de l'eau ; un inhibiteur de type azole ; un agent tensio-actif organique de métal alcalin ; un hydrotrope ; un agent contenant du phosphore ; éventuellement, un polymère non saccharidique hydrosoluble ; éventuellement, un composé acide hydrosoluble de formule I ; éventuellement, un agent complexant ; éventuellement, un agent oxydant ; éventuellement, un solvant organique ; éventuellement, un abrasif. Par ailleurs il est également fourni un procédé de fabrication d'une composition de la présente invention et un procédé de polissage chimico-mécanique d'un substrat, comprenant : la fourniture d'un substrat, le substrat étant une plaquette de semi-conducteurs avec interconnexions en cuivre ; la fourniture d'une composition selon la présente invention ; la fourniture d'un tampon ...

VEHICLE COMPRISING A DEFLECTING DEVICE AND DEFLECTOR DEVICE

L'invention concerne un véhicule (10), comprenant des supports longitudinaux avant (11) s'étendant vers l'avant à partir d'un habitacle de conduite (12), qui délimitent en partie un compartiment moteur (13) dans lequel est positionné un groupe motopropulseur (14), et comprenant un dispositif déflecteur (17) présentant des éléments déflecteurs (18) fixés de manière à pouvoir tourner autour d'un axe de rotation vertical (24) au niveau des supports longitudinaux avant (11), un élément déflecteur (18) pouvant être tourné en cas de collision frontale depuis une position de repos dans une position de collision par rapport au support longitudinal avant respectif (11), de telle sorte qu'une première portion (19) de l'élément déflecteur (18) pénètre dans le compartiment moteur (13) et convertisse une impulsion longitudinale de la collision frontale, au moins en partie en une impulsion transversale.

AC-DC CONVERTER

Convertisseur alternatif - continu (100) destiné à être intégré dans une machine électrique tournante, comprenant : - au moins un module de puissance (12), - un module de contrôle permettant de contrôler le au moins un module de puissance (12), - un dispositif de refroidissement (14), dans lequel le au moins un module de puissance (12) est fixé au dispositif de refroidissement (14) par l'intermédiaire d'au moins un moyen de fixation (23), et le module de contrôle repose sur le au moins un moyen de fixation (23) de sorte à transférer la chaleur générée par au moins une partie du module de contrôle vers le dispositif de refroidissement (14).

METHOD FOR RECONSTRUCTING IMAGE FOR COMPUTERIZED TOMOGRAPHIC IMAGING SYSTEM OF DUAL ENERGY HIGH ENERGY

Un procédé de reconstruction d'image dans un système de CT de double énergie à haute énergie est décrit. Le procédé comprend les étapes consistant à balayer (S11) un objet avec des rayons de double énergie à haute énergie pour obtenir des valeurs de projection de double énergie à haute énergie, calculer (S 12) les valeurs de projection des coefficients du matériau de base correspondant aux valeurs de projection à double énergie en se basant sur un tableau de correspondance créé à l'avance ou en résolvant de façon analytique un système d'équations, et obtenir (S13) une image de la distribution des coefficients du matériau de base en se basant sur les valeurs de projection des coefficients du matériau de base. Le procédé fournit une solution pour la reconstruction avec une technologie de CT de double énergie à haute énergie et ainsi, une approche plus efficace d'identification de substances et de contrôle de contrebande, en apportant ainsi une amélioration significative à la précision et ...

IMAGING WITH SHIELD FOR MOTOR VEHICLE

On propose un dispositif d'imagerie (300) pour véhicule automobile. Le dispositif d'imagerie comprend un écran (110) à transmission ou réflexion variable dans une pluralité de zones pilotables sélectivement, l'écran étant configuré pour la formation d'une image, une source lumineuse (130-136) cohérente apte à éclairer ledit écran, et un vibreur électromécanique (316-318) configuré pour mettre en vibration au moins une partie de la source lumineuse. Cela offre un dispositif d'imagerie pour véhicule automobile amélioré.

HYDRAULIC SHOCK ABSORBER

L'invention divulgue un amortisseur hydraulique comprenant un rotor (1), un stator (2) et un arbre d'entraînement (3) pour entraîner le rotor (1), le rotor (1) et le stator (2) formant mutuellement une chambre de travail (4) dans laquelle un milieu liquide est contenu, dans lequel le stator (2) est pourvu à son tour d'une sortie (21), d'une buse (22), d'un canal d'échappement (23), d'un canal éjecteur (24) et d'une entrée (25) ; la sortie (21), le canal d'échappement (23) et l'entrée (25) sont mis en communication avec la chambre de travail (4), respectivement ; le canal éjecteur (24) est en communication avec la sortie (21), le canal d'échappement (23) et l'entrée (25), respectivement ; la buse (22) est agencée à la jonction où la sortie (21) est connectée au canal d'échappement (23) et au canal éjecteur (24) ; la buse (22) est étendue le long de la direction de sortie de la sortie (21) à la jonction où le canal d'échappement (23) est connecté au canal éjecteur (24) et la largeur de canal ...

Door e.g. front door, closure authorization determining method for e.g. bus, involves comparing outer environmental states of door, and preventing closing of door when environmental states are different

Un dispositif avec une fonction de mémoire pour déterminer si ou non une porte de véhicule est autorisée à se fermer et son procédé sont décrits. Avant qu'une porte de véhicule ne soit ouverte, un signal de détection près du côté extérieur de la porte est émis et son état de détection est enregistré. Lorsque la porte de véhicule doit être fermée, un premier signal de détection est émis à partir de la partie supérieure du cadre de porte vers le bas et un second signal de détection est émis près du côté extérieur de la porte. Si le premier signal de détection indique qu'une personne est au niveau de la porte ou que le second signal de détection indique qu'une personne est présente sur le côté extérieur de la porte par comparaison avec un enregistrement précédent, alors on empêche la porte de se fermer. Sinon, la porte peut être fermée.

DEVICE HAS PART OF CHANGE-OVER CONTACT FOR the INTERRUPTION OF the CURRENT LIKE DISCONNECTING SWITCH USING the DEVICE

Dispositif à pièce de contact double pour l'interruption du courant, qui comporte un corps ( 12 ), une partie ( 11 ) d'entraînement une première pièce ( 21 ) de contact statique, une deuxième pièce ( 31 ) de contact statique, une première pièce ( 22 ) de contact mobile, une deuxième pièce ( 32 ) de contact mobile, la partie ( 11 ) d'entraînement est reliée au corps ( 12 ) au moyen d'un axe ( 17 ), tandis que la première pièce ( 21 ) de contact statique et la deuxième pièce ( 31 ) de contact statique, la première pièce ( 22 ) de contact mobile et la deuxième pièce ( 32 ) de contact mobile, sont disposés symétriquement par rapport à l'axe ( 17 ) principal.

EMPENNAGE ABLE TO IMPROVE the PERFORMANCES the ANTI-COLLISION one WITH a BIRD Of a PLANE

Selon la présente invention, un renfort de bord d'attaque (6) ayant une forme de triangle isocèle est situé à l'intérieur d'un bord d'attaque d'empennage. Le renfort de bord d'attaque (6) est fixé dans le sens de l'envergure dans des sections entre des étendues respectives formées par la nervure d'aile (8). Les degrés de l'angle au sommet du renfort de bord d'attaque (6) sont les mêmes que les degrés de l'angle au sommet du revêtement de bord d'attaque d'empennage (5). Le renfort de bord d'attaque (6) est relié de façon fixe au petit longeron avant (7) par une surface de fixation de renfort de bord d'attaque (11). Lorsque l'aile est frappée par un oiseau, le revêtement de bord d'attaque se colle sur la structure de support en triangle afin de segmenter l'énergie de l'oiseau de façon à protéger le longeron avant d'empennage contre une rupture.

PHOSPHOR OXICARBONITRIDE HALOGEN AND DEVICES USING SAME

La présente invention concerne un luminophore rouge, comprenant : un composé inorganique représenté par la formule (1) M(I)eM(II)fM(III)gSijNuCxOwHv:zA (1) où M(I) est au moins un cation monovalent ; où M(II) est au moins un cation divalent ; où M(III) est au moins un cation trivalent ; où H est au moins un anion monovalent d'halogène; où A est au moins un activateur de luminescence ; où 0 < e ≤ 0,5 ; où 0,5 ≤ f≤ 1 ; où 0,5 ≤ g ≤ 1 ; où 1 ≤ j < 1,5 ; où 0 < u < 3 ; où 0 < x ≤ 2 ; où 0 < w≤ 0,75 ; où 0 < v < 1 ; où 0 < (x+w) < 3 ; où x≠w; et, où 0 < z≤ 0,5. La présente invention concerne en outre un appareil d'éclairage contenant un luminophore rouge.

GRILL DEVICE

SENSOR Of INFRA-RED AND PROCEEDED IMAGEUR Of VACUUM PACKAGING.

Un capteur d'image infrarouge et un procédé d'encapsulage sous vide sont présentés. Le capteur d'image infrarouge comprend un support en céramique (210), un couvercle en métal (220) et un filtre infrarouge (230). Le support en céramique (210) a une plaque de capture d'image infrarouge (240) fixée dessus et le couvercle en métal (220) comprend un dégazeur (221) déposé sur une face intérieure du couvercle en métal (220). Le filtre d'infrarouge (230) scelle une ouverture du couvercle en métal (220). Le support en céramique (210), le couvercle en métal (220) et le filtre infrarouge (230) sont chauffés dans une chambre à vide pour activer le dégazeur (221) et souder ensemble le support en céramique (210), le couvercle en métal (220) et le filtre infrarouge (230), encapsulant ainsi sous vide le capteur d'image infrarouge.

DEVICE HAS EMISSION OF FIELD

En modelant une couche de catalyseur à une échelle micrométrique et en construisant des nanotubes (103) sur celle-ci, la zone d'émission est constituée de nombreux petits îlots d'émission. Chaque îlot d'émission comporte des nanotubes finis (103) à densité nominale. Du fait du très grand nombre d'espaces entre les îlots d'émission, relativement plus de nanotubes (103) sont exposés à la région du bord de l'émetteur, ce qui accroît efficacement l'espacement mutuel moyen des nanotubes (103). L'effet d'arrêt de champs est ainsi très réduit.

COMPOSITION OF POLISHING CHEMICO-MECANICAL, CONCENTRABLE, STABLE AND PROCEEDED BEING ATTACHED TO it

Une composition de polissage chimico-mécanique utile pour polissage d'une plaquette de semi -conducteurs contenant un métal d'interconnexion, est fournie, comprenant, en tant que composants initiaux : de l'eau ; un inhibiteur de type azole ; un agent tensio-actif organique de métal alcalin ; un hydrotrope ; un agent contenant du phosphore ; une cellulose hydrosoluble ; éventuellement, un polymère non saccharidique hydrosoluble ; éventuellement, un composé acide hydrosoluble de formule I, éventuellement, un agent complexant; éventuellement, un agent oxydant ; éventuellement, un solvant organique ; éventuellement, un abrasif. Par ailleurs est également fourni un procédé de préparation d'une composition de la présente invention et un procédé de polissage chimico-mécanique d'un substrat, comprenant : la fourniture d'un substrat, le substrat étant une plaquette de semi- conducteurs à interconnexions en cuivre ; la fourniture d'une composition selon la présente invention ; la fourniture d'un ...

METHOD AND APPARATUS FOR RECYCLING AND REFINING OF PROPYLENE

Un procédé de recyclage et de raffinage du propylène est proposé selon la présente divulgation. La présente divulgation vise à résoudre le problème de la consommation élevée d'énergie de l'art antérieur. Un appareil de recyclage du propylène comprenant une première colonne de récupération de propylène (I), un ballon de détente (III), une deuxième colonne de récupération de propylène (IV), et une colonne de dépropanisation (II) selon la présente divulgation peut résoudre efficacement le problème, et être utilisé pour la fabrication industrielle de propylène récupéré à partir d'un appareil de production d'oxyde de propylène.

METHOD FOR ALLOCATING RESOURCES IN THE ACCESS NETWORK, BASE STATION, COMPUTER PROGRAM PRODUCT AND CORRESPONDING INFORMATION CARRIER

La présente invention se rapporte à un procédé d'allocation de porteuse et de détermination de puissance émise pour Mi communications montantes (UU) et Ni communications descendantes (DU) entre des mobiles half-duplex et une station de base i parmi L stations de base d'un réseau d'accès full-duplex. Une bande fréquentielle de K porteuses est allouée pour les L stations de base avec un accès au canal de transmission de type OFDMA. Pour maximiser un débit somme du réseau d'accès, le procédé considère le Lagrangien duale du débit somme en faisant apparaître dans son expression des variables {Ym} et λ multiplicatives respectivement d'une contrainte sur les puissances maximales émises par des mobiles {m} et d'une puissance maximale émise par une station de base i. Le procédé détermine de manière itérative l'ensemble des triplets porteuse et paires de puissance qui optimise l'expression duale pour les valeurs des variables {Ym} et λ.

Electronic device with cover having internal protruding portions for dispersing of sound

An exemplary electronic device includes a box, a speaker, and a micro structure. The box includes a shell and a cover disposed on the shell. The speaker is sandwiched between the shell and the cover. The micro structure includes a plurality of flat-bottomed protruding portions, a plurality of first pyramidal protruding portions, and a plurality of second pyramidal protruding portions.

Electronic device having detector window

An electronic device includes a body, a detector window, and a fixing mechanism for securing the detector window to the body. The detector window is capable of being inserted into the body in a first direction, and includes at least one hook member. The fixing mechanism includes at least one latching member, at least one first limiting member and at least one second limiting member. The at least one latching member hooks the at least one hook member to limit the movement of the detector window in the first direction. The at least one latching first limiting member and the at least one second limiting member respectively are arranged opposite sides of the latching member and respectively resisting against opposite sides of the at least one hook member to cooperatively limit the movement of the detector window in a second direction perpendicular to the first direction.

N-Type Silicon Solar Cell With Contact/Protection Structures

A solar cell is formed on an n-type semiconductor substrate having a p+ emitter layer by forming spaced-apart contact/protection structures on the emitter layer, depositing a blanket dielectric passivation layer over the substrate's upper surface, utilizing laser ablation to form contact openings through the dielectric layer that expose corresponding contact/protection structures, and then forming metal gridlines on the upper surface of the dielectric layer that are electrically connected to the contact structures by way of metal via structures extending through associated contact openings. The contact/protection structures serve both as protection against substrate damage during the contact opening formation process (i.e., to prevent damage of the p+ emitter layer caused by the required high energy laser pulses), and also serve as optional silicide sources that facilitate optimal contact between the metal gridlines and the p+ emitter layer. 1. A solar cell comprising:a semiconductor substrate having an upper surface and including a body layer and a emitter layer disposed between the upper surface and the body layer;a plurality of spaced-apart contact structures disposed over first portions of the upper surface, each of the plurality of spaced-apart contact structures having a minimum lateral dimension;a dielectric passivation layer disposed over the upper surface such that the dielectric passivation layer is disposed on the plurality of spaced-apart contact structures and on second portions of the upper surface disposed between the plurality of spaced-apart contact structures;a plurality of metal gridlines disposed on an upper surface of the passivation layer; anda plurality of metal via structures extending through associated openings defined in the passivation layer such that each metal via structure electrically connects an associated metal gridline of the plurality of metal gridlines and an associated contact structure of the plurality of contact structures, ...

True Color Liquid Crystal Displaying Device

A true color liquid crystal displaying device is disclosed in the present invention. The true color liquid crystal displaying device includes a light guide module, a LED light source, and a liquid crystal panel without a color filter. The light guide module includes a light guide body, an optical input portion and an emitting surface. The emitting surface includes an emitting area. The LED light source is disposed on the optical input portion of the light guide module for emitting RGB beams. The liquid crystal panel is disposed above the emitting surface of the light guide module. The emitting area aligns with a sub-pixel of the liquid crystal panel. The optical cable inside the light guide module guides the monochromatic beam from the LED light source to each corresponding sub-pixel of the liquid crystal panel, so that the RGB beams is the pixel of the true color performance. 1. A true color liquid crystal displaying device comprising:a light guide module, the light guide module comprising a light guide body, an optical input portion and an emitting surface, the emitting surface comprising an emitting area;a light emitting diode (LED) light source disposed on the optical input portion of the light guide module for emitting RGB beams; anda liquid crystal panel disposed above the emitting surface of the light guide module, the emitting area aligning with a sub-pixel of the liquid crystal panel, the beam from the LED light source being transmitted into the light guide module via the optical input portion, and being further transmitted into the liquid crystal panel via the light guide body and the emitting area on the emitting surface;wherein the liquid crystal panel does not comprise a color filter.2. The true color liquid crystal displaying device of claim 1 , wherein the LED light source is embedded in or outwardly disposed on the optical input portion of the light guide module claim 1 , an external optical cable is disposed between the LED light source and the ...

PROXIMITY DETECTION DEVICE AND MOBILE TERMINAL

A proximity detection device includes: a mobile terminal antenna body and a mobile terminal side metal strip, configured to detect capacitance of a space between the mobile terminal antenna body and the mobile terminal side metal strip; and a capacitance detection sensor circuit, electrically coupled to the mobile terminal antenna body and the mobile terminal side metal strip, and configured to determine whether a person is approaching according to the capacitance detected by the mobile terminal antenna body and the mobile terminal side metal strip, and output an indication signal when it is determined that a person is approaching, so as to indicate that a person is approaching. 1. A proximity detection device , comprising:a mobile terminal antenna body and a mobile terminal side metal strip, forming two electrodes of a capacitor, and configured to detect capacitance of a space between the mobile terminal antenna body and the mobile terminal side metal strip; anda capacitance detection sensor circuit, electrically coupled to each of the mobile terminal antenna body and the mobile terminal side metal strip, and configured to determine whether a person is approaching according to the capacitance detected by the mobile terminal antenna body and the mobile terminal side metal strip, and output an indication signal when it is determined that a person is approaching.2. The device according to claim 1 , wherein the capacitance detection sensor circuit comprises a capacitance-to-digital converter claim 1 , a register claim 1 , and a comparator claim 1 , whereinthe capacitance-to-digital converter is configured to convert the capacitance detected by the mobile terminal antenna body and the mobile terminal side metal strip into a first capacitance value;the register is configured to store a second capacitance threshold, wherein the second capacitance threshold is a corresponding capacitance value when a person is approaching; andthe comparator is configured to determine ...

Negative pressure wound therapy system with a buffering unit

A negative pressure wound therapy system has a buffering unit connected between an actuator and a wound dressing. The buffering unit has similar physical condition with the wound, and consumes its negative pressure to compensate for the negative pressure loss in the wound to resist the pressure rise in the wound during slight leakage. The buffering unit also keeps the actuator from directly operating on the wound to reduce the pain of the patient while lowering the pressure in the wound.

Mechanical Method For Producing Micro- Or Nano-Scale Textures

A mechanical method for producing micro-scale and nano-scale textures that facilitates, for example, the cost-effective production of nanostructures on large-scale substrates, e.g., during the large-scale production of thin-film solar cells. A “scratcher” (multi-pointed abrasion mechanism) is maintained in a precise position relative to a target substrate such that micron-level features (protrusions) extending from the scratcher's base structure are precisely positioned to contact a surface material layer of the target substrate with a predetermined amount of force, and then moved relative to the substrate (e.g., by way of a conveying mechanism) while maintaining the pressing force such that the micron-level features define elongated parallel nano-scale grooves and/or form nano-scale ridges in the surface material layer (i.e., by mechanically displacing) portions of the surface material layer to form the nano-scale grooves/ridges). 1. A method for producing textures on a substrate comprising a surface material layer , the method comprising:{'b': '106', 'pressing a scratcher against the substrate, the scratcher including a base structure and a plurality of micron-level features protruding away from the base structure, wherein pressing the scratcher comprises biasing the scratcher against the substrate such that at least some of the plurality of micron-level features pierce an outer surface of the surface material layer; and'}moving the scratcher relative to the substrate such that at least some of the plurality of micron-level features displace portions of said surface material layer in a manner that produces parallel elongated grooves defined in the surface material layer and separated by parallel elongated ridges formed by remaining portions of the surface material layer.2. The method according to claim 1 , wherein moving scratcher relative to the substrate comprises maintaining the scratcher in a stationary position over the substrate while utilizing a conveying ...

Antibody-urease conjugates for therapeutic purposes

Pharmaceutical compositions comprising antibody-urease conjugates and substantially free of unconjugated urease are disclosed. These compositions are prepared by a method that does not require chromatographic purification. These pharmaceutical compositions have utility in the treatment of cancer by antibody-directed enzyme prodrug therapy wherein the urease converts endogenous urea into ammonia in situ to induce cytotoxicity.

Car immune cells to treat cancers

A chimeric antigen receptor (CAR) that binds to CEACAM6, an epitope or fragment thereof, or a variant thereof.

SILICON-CONTAINING COMPOUND FOR RESISTANCE TO HEPATITIS C VIRUS INFECTION

The present invention provides a silicon-containing compound for resistance to hepatitis c virus infection, and in particular provides a compound represented by formula I, or a pharmaceutically acceptable salt, or a tautomer, or a stereoisomer, or a deuterated compound thereof and mixture among them, a preparation process therefor, and a pharmaceutical composition comprising the same. The present application also provides a use of the compound, or a pharmaceutically acceptable salt, or a tautomer, or a stereoisomer, or a deuterated compound thereof and mixture among them, and a pharmaceutical composition comprising the same in treatment of hepatitis c virus infection. 3. The compound according to claim 1 , wherein Rand Rare each independently selected from Calkyl claim 1 , or Rand Rare joined to form a 3- to 8-membered silicon-containing saturated aliphatic ring containing 1 silicon atom.4. The compound according to claim 1 , wherein Rand Rare each independently selected from the group consisting of methyl claim 1 , ethyl claim 1 , n-propyl claim 1 , isopropyl claim 1 , t-butyl claim 1 , n-butyl claim 1 , isobutyl and phenyl claim 1 , or Rand Rare joined to form a 3- claim 1 , 4- claim 1 , 5- or 6-membered silicon-containing saturated aliphatic ring claim 1 , wherein the silicon-containing saturated aliphatic ring contains one silicon atom.5. The compound according to claim 1 , wherein R claim 1 , R claim 1 , Rand Rare each independently selected from the group consisting of hydrogen claim 1 , fluoro claim 1 , and chloro; preferably claim 1 , Rand Rare each independently selected from the group consisting of hydrogen and fluoro claim 1 , and Rand Rare selected from hydrogen; preferably claim 1 , one of Rand Ris fluoro claim 1 , and the other is hydrogen claim 1 , and Rand Rare selected from hydrogen; and preferably claim 1 , Rand Rare selected from fluoro claim 1 , and Rand Rare selected from hydrogen.8. The compound according to claim 1 , wherein Rand Rare each ...

Broadband and Omnidirectional Polymer Antireflection Coatings

A method for generating antireflective coatings for polymeric substrates using a deposition process and/or a dissolving process can provide a coating onto the outer surface of the substrate. Some embodiments can include a GLAD generated fluoropolymer coating or a co-evaporated fluoropolymer coating on a substrate that may achieve ultralow refractive index as well as improved adhesion and durability properties on polymeric substrates. In some embodiments, the deposition process is performed such that a fluoropolymer can be evaporated to form chain fragments of the fluoropolymer. The chain fragments diffused into the substrate can subsequently re-polymerize, interlocking with the polymer chains of the substrate. In some embodiments, the co-evaporation process can form a nanoporous polymer chain scaffold of the fluoropolymer, from which a sacrificial material can be dissolved out. The formed coating can be a multilayer or continuously-graded antireflective coating that has strong adhesion with the substrate. 1. A method of generating an antireflective coating , the method comprising:forming a coating on a surface of a polymeric substrate via a deposition process, the forming of the coating onto the surface of the substrate occurring such that:the coating material is vaporized to form chain fragments of the coating material during vaporization of the coating material, the vaporized chain fragments are subsequently diffused into the surface of the polymeric substrate to a depth into the surface of the substrate as layers of the chain fragments are applied onto the surface of the substrate, and the chain fragments diffused into the substrate are subsequently re-polymerized to interlock with polymer chains of the substrate.2. The method of claim 1 , wherein the coating material comprises a fluoropolymer.3. The method of claim 1 , wherein the coating material comprises a polymetric material.4. The method of claim 1 , wherein the substrate is plastic claim 1 , acrylic or ...

ELECTROLYTE REPLENISHMENT METHOD FOR MOLTEN CARBONATE FUEL CELL STACK

A method for replenishing an electrolyte of a molten carbonate fuel cell stack includes: preparing an electrolyte colloidal solution containing 10% to 20% of the electrolyte and having a viscosity of 200 to 800 Pa·s; replenishing the electrolyte of the cell stack using the electrolyte colloidal solution prepared in step 1 to allow the electrolyte to adhere to an electrode and an internal channel of the cell stack; discharging excess electrolyte colloidal solution in the cell stack; and drying and discharging water or an organic solvent in the cell stack under an inert gas condition to complete replenishment of the electrolyte of the cell stack, and performing a discharge performance test. 1. A method for replenishing an electrolyte of a molten carbonate fuel cell stack , comprising:step 1: preparing an electrolyte colloidal solution containing 10% to 20% of the electrolyte and having a viscosity of 200 to 800 Pa·s;step 2: replenishing the electrolyte of the cell stack using the electrolyte colloidal solution prepared in step 1 to allow the electrolyte to adhere to an electrode and an internal channel of the cell stack;step 3: discharging excess electrolyte colloidal solution in the cell stack; andstep 4: drying and discharging water or an organic solvent in the cell stack under an inert gas condition to complete replenishment of the electrolyte of the cell stack, and performing a discharge performance test.2. The method for replenishing the electrolyte of the molten carbonate fuel cell stack according to claim 1 , wherein the electrolyte colloidal solution in step 1 is prepared by:mixing lithium carbonate and potassium carbonate in a molar ratio of 62:38 to form the electrolyte; andmixing the obtained electrolyte with an aqueous solution of polyvinyl alcohol with a concentration of 0.5% to 3%, or with a mixed solution of polyvinyl butyral and ethanol with a concentration of 95% to prepare the electrolyte colloidal solution containing 10% to 20% of the electrolyte ...

THERMAL COOLING SYSTEM

Particular embodiments described herein provide for a device that can include at least one heat source and a vapor chamber, where the vapor chamber is bigger than the at least one heat source and a portion of the vapor chamber is in direct contact with the at least one heat source, where the portion of the vapor chamber in direct contact with the at least one heat source does not include a stiffener. In an example, the device can include a first air mover on a first side of the at least one heat source and a second air mover on an opposite side of the at least one heat source. Exhaust from the first air mover can pass through a vented foot and exhaust from the second air mover can pass through a second vented foot. 1. A device comprising:at least one heat source; anda vapor chamber, wherein the vapor chamber is bigger than the at least one heat source and a portion of the vapor chamber is in direct contact with the at least one heat source, wherein the portion of the vapor chamber in direct contact with the at least one heat source does not include a stiffener.2. The device of claim 1 , further comprising:at least one fin array coupled to the vapor chamber.3. The device of claim 2 , wherein the at least one fin array is soldered to the vapor chamber.4. The device of claim 2 , further comprising:at least one air mover.5. The device of claim 4 , wherein the at least one air mover directs air through the at least one fin array.6. The device of claim 1 , further comprising:a first air mover on a first side of the at least one heat source; anda second air mover on an opposite side of the at least one heat source.7. The device of claim 1 , further comprising:a first air mover on a first side of the at least one heat source;a first fin array soldered to a first side of the vapor chamber, wherein exhaust from the first air mover can pass through the first fin array;a second air mover on an opposite side of the at least one heat source; anda second fin array soldered to a ...

AUTOMATIC HUB FORGING DIE LUBRICANT CLEANING DEVICE

Disclosed is an improved automatic hub forging die lubricant cleaning device, comprising a lifting hydraulic cylinder, a limiting block, a hinge A, a hydraulic piston rod, a fixed connecting rod, a hinge shaft, a connecting plate, a hydraulic cylinder, a hinge B and the like. The device has the advantages that the labor efficiency is improved, the production intensity is reduced, and the generality is strong; and corresponding cleaning scrapers can be set according to the surface shapes of different hub dies and only need to be replaced via general bolt connectors, so that the cost of equipment is reduced. 1the main body frame is of a structure comprising four upright posts and an upper crossbeam, a middle crossbeam and a lower crossbeam, the support crossbeam is the middle crossbeam, and the foundation crossbeam is the lower crossbeam; the servo motor is fixed below a large plate of the support crossbeam, the shaft of the servo motor is connected with the lower rotating shaft of the die supporting tray, and the die supporting tray is attached to the bottom of a die; two positioning pins are arranged on the die supporting tray, and the positioning pins are connected with bottom positioning holes of the die to ensure that the supporting tray drives the die to rotate; the rolling bearings are arranged below the die supporting tray and on the large plate of the support crossbeam to ensure the die supporting tray rotates at a low speed; the left hydraulic cylinder assembly is arranged on an upright post plate on the left side of an upright post of the main body frame via a connecting screw, and the left lubricant cleaning scraper is connected with the piston rod of the left hydraulic cylinder assembly; the hydraulic cylinder fixing seat is fixed in the middle of the right side of the main body frame, the hydraulic cylinder is connected with the hydraulic cylinder fixing seat via the hinge shaft, the hydraulic piston rod is connected with the fixed connecting rod via the ...

THERMAL MANAGEMENT STAND FOR PORTABLE COMPUTING DEVICE

Various portable computing device thermal management stands and methods of using and making the same are disclosed. In one aspect, a stand for supporting and thermally managing a portable computing device that has a first surface is provided. The stand includes a support plate that has a second surface to contact the first surface of the computing device and transfer heat from the computing device by conduction. The stand is operable to transfer heat received from the computing device to the ambient environment. A wall coupled to the support plate may be used to bear against a member supporting the stand to provide stability. 1. A method of thermally managing a portable computing device , comprising:placing the portable computing device on a stand having a support plate with a first surface wherein a second surface of the portable computing device contacts the first surface of the support plate;transferring heat from the computing device to the support plate by conduction; andtransferring heat received by the stand from the computing device to the ambient environment.2. The method of claim 1 , wherein the stand comprises a first wall coupled to the support plate and adapted to bear against a member supporting the stand.3. The method of claim 2 , wherein the member comprises an electronic device claim 2 , the method comprising placing the stand on the electronic device.4. The method of claim 2 , wherein the first wall is pivotally coupled to the support plate.5. The method of claim 1 , comprising placing a thermal interface material between the first surface and the second surface.6. The method of claim 1 , wherein the stand comprises at least one thermoelectric cooler.7. The method of claim 1 , comprising coating at least a portion of the stand with a thermally emissive coating.8. The method of claim 1 , comprising coupling a heat sink to the stand.9. A method of manufacturing a stand for supporting and thermally managing a portable computing device having a first ...

DOCKING SYSTEMS AND METHODS FOR ELECTRONIC DEVICES

Illustrative examples include a docking system for a foldable electronic device such as a 2-in-1 convertible computer. The docking system may include a housing having an engagement surface to interface with a portion of the foldable electronic device when the foldable electronic device is operably engaged with the docking system. The engagement surface may include a vent opening arranged to direct airflow in between a first portion and a second portion of the plurality of portions, and a separator to maintain separation between the first portion and the second portion when the foldable electronic device is operably engaged with the engagement surface. A blower coupled to the housing may supply airflow through the vent opening. 1. A docking system for a foldable electronic device , the foldable electronic device having a plurality of portions that are foldable with respect to each other , the docking system comprising:a housing having an engagement surface to interface with a portion of the foldable electronic device when the foldable electronic device is operably engaged with the docking system, the engagement surface including:a vent opening arranged to direct airflow in between a first portion and a second portion of the plurality of portions when the foldable electronic device is operably engaged with the engagement surface; anda separator configured to be disposed between the first portion and the second portion of the foldable electronic device to maintain a separation between the first portion and the second portion when the foldable electronic device is operably engaged with the engagement surface, wherein the separator maintains the separation allowing air flow from the vent opening through the separation between the first portion and the second portion; anda blower coupled to the housing to supply airflow through the vent opening.2. The docking system of claim 1 , wherein the separator is wedge shaped.3. The docking system of claim 1 , wherein the ...

Networking Method for Multi-Site Cell, Base Band Unit, Remote RF Unit and System

Embodiments of the present invention provide a networking method applied to a multi-site cell, a base band unit, a remote RF unit and a system. The method includes: connecting at least one RRU of one or more remote end remote units RRUs under a base station of a local cell to at least two base stations. The at least two base stations include the base station of the local cell and at least one other base station. Communication, is continued by using the at least one other base station when the communication between the one RRU of the one or more RRUs and the base station of the local cell fails. 1. A networking method applied to a multi-site cell , the method comprising:connecting one remote radio frequency unit (RRU) of one or more RRUs under a base station of a local cell to at least two base stations, wherein the at least two base stations comprise a base station of the local cell and at least one other base station;communicating between the one RRU of the one or more RRUs and the base station of the local cell; andcontinuing communication by using the at least one other base station when a communication failure occurs between the one RRU of the one or more RRUs and the base station of the local cell.2. The method according to claim 1 , wherein continuing the communication by using the at least one other base station comprises:in a case of chain networking,when the communication failure is caused by a fault of an optical fiber, switching the RRU at a fault point and a residual RRU that is after the RRU at the fault point according to a chain sequence to one of the at least one other base station; andwhen the communication failure is caused by a fault of a base band unit (BBU) in the base station of the local cell, switching the RRU under the base station of the local cell to the at least one other base station.3. The method according to claim 2 , wherein claim 2 , when the communication failure is caused by the fault of the BBU in the base station of the local ...

RESTORING FUNCTION OF TUMOUR ACIDIFIED T CELLS

Methods and compositions to restore function to acidified T cells are provided. The methods comprise administering urease to the T cells. Compositions comprise urease. 1. A method for restoring function to acidified T cells , the method comprising administering urease to the T cells.2. The method of claim 1 , wherein restoring function comprises increasing production of cytokines.3. The method of claim 2 , wherein the cytokines comprise IL-2.4. The method of claim 1 , wherein the T cells are acidified relative to physiological pH such that the T cells have a pH of less than about 7.2 claim 1 , less than about 7.1 claim 1 , less than about 7.0 claim 1 , less than about 6.9 claim 1 , or less than about 6.8.5. The method of claim 4 , wherein the T cells are acidified with lactate produced by a solid tumor.6. The method of claim 1 , wherein the T cells are in the presence of urea claim 1 , either native or administered.7. The method of claim 1 , wherein the T cells express PD-1 claim 1 , optionally at higher than normal levels compared to a non-acidified T cell and wherein the urease inhibits PD-1 expression and/or activation.8. The method of claim 1 , wherein the urease is conjugated to a targeting moiety.9. The method of claim 8 , wherein the targeting moiety is an antibody specific for a tumor-associated antigen.10. The method of claim 8 , wherein the tumor-associated antigen is CEACAM6.11. The method of claim 10 , wherein the antibody is an AFAIKL2 antibody or a 2A3 antibody.12. The method of claim 1 , wherein the urease inhibits PD-L1 expression on acid sensitive cancer cells.13. The method of claim 1 , further comprising administering to said acidified T cells an active agent selected from a PD-1 inhibitor claim 1 , a chemotherapeutic agent claim 1 , radiation claim 1 , a hormone claim 1 , a cytokine such as IL-2 and combinations thereof.14. The method of claim 1 , in conjunction with immunotherapy claim 1 , such as adoptive T cell therapy.15. The method of claim ...

Optical Lens

The invention relates to an optical lens utilized for disposing above a light source. The optical lens has rotational symmetry relative to the central axis thereof. The central axis of the optical lens aligns with the center of the light source. The optical lens includes a bottom surface, an emergence surface with arc shape, an incidence surface with arc and concave shape, a curved surface with annular and concave shape and a light diffusing structure. The emergence surface connects a side of the bottom surface. The incidence surface connects another side of the bottom surface and lies in the middle of the bottom surface. The curved surface lies on the bottom surface and connects the incidence surface. The light diffusing structure is disposed on the curved surface. The invention improves the distribution of light projected on a light receiving surface and prevents a bright circle formed on the light receiving surface as a result of a gap that is formed by assembly tolerance of the optical lens and the light source. 1. An optical lens , utilized for positioning above a light source , having rotational symmetry relative to a central axis thereof aligning with a center of the light source and comprising:a bottom surface;an emergence surface with arc shape connecting a side of the bottom surface;an incidence surface with arc and concave shape connecting another side of the bottom surface and lying in the middle of the bottom surface;a curved surface with annular and concave shape lying on the bottom surface and connecting the incidence surface; anda light diffusing structure disposed on the curved surface.2. The optical lens of claim 1 , wherein the light diffusing structure includes a plurality of convex points or a plurality of concave points distributed continuously.3. The optical lens of claim 2 , wherein a radius of the convex point or a radius of the concave point is less than 0.5 mm.4. The optical lens of claim 1 , wherein an edge of the bottom surface includes ...

Mobile device cooling and performance management

Disclosed is a mobile device. The mobile device may be located proximate a mobile terminal and controlled by the mobile terminal. The mobile device may include a processor and a memory. The memory may store instructions that, when executed by the processor, cause the processor to: determine a mode of operation of the mobile device, determine a thermal profile for the mode of operation of the mobile device, and implement a power profile to achieve the thermal profile.

PERFORMANCE STATE BOOST FOR MULTI-CORE INTEGRATED CIRCUIT

An integrated circuit includes a multiple number of processor cores and a system management unit. The multiple number of processor cores each operate at one of a multiple number of performance states. The system management unit is coupled to the multiple number of processor cores, for setting performance states of the multiple number of processor cores. The system management unit boosts a first performance state of a first processor core of the multiple number of processor cores based on both a first temperature calculated from an estimated power consumption, and a second temperature based on a temperature measurement. 1. An integrated circuit comprising:a plurality of processor cores, each operating at one of a plurality of performance states; anda system management unit coupled to said plurality of processor cores, for setting performance states of said plurality of processor cores, and boosting a first performance state of a first processor core of said plurality of processor cores based on both a first temperature calculated from an estimated power consumption, and a second temperature based on a temperature measurement.2. The integrated circuit of claim 1 , wherein said system management unit boosts said performance state based on said first temperature if a system temperature is below a predetermined temperature.3. The integrated circuit of claim 2 , wherein said predetermined temperature is a nominal system temperature.4. The integrated circuit of claim 2 , wherein said system management determines said system temperature as a difference between said second temperature and said first temperature.5. The integrated circuit of claim 1 , wherein each of said plurality of processor cores comprises a respective digital power monitor responsive to a plurality of activity signals to provide a respective estimated power consumption.6. The integrated circuit of claim 5 , wherein said system management unit forms said estimated power consumption based on said respective ...

OXANORBORNADIENE DERIVATIVES AND THEIR ANTICANCER ACTIVITIES

The present invention relates to chemical entities originated from natural sources and further synthesized for therapeutic uses. More particularly, the present invention relates to norcantharidin analogues synthesized by a transition metal-catalyzed alkynylation of oxanorbornadiene derivatives and their antitumor effects. 3. The composition of claim 1 , wherein oxanorbornadiene derivatives are first isolated from a natural source or obtained from a chemically synthesized compound claim 1 , followed by reacting said oxanorbornadiene derivatives with a chemical ligand under a transition metal-catalyzed alkynylation reaction in the presence of a solvent in order to result in said norcantharidin analogues.4. The composition of claim 3 , wherein a transition metal used in said transition metal-catalyzed alkynylation reaction is an iridium-based compound.5. The composition of claim 4 , wherein said iridium-based compound comprises Ir(I)(COD)Cl claim 4 , [Ir(I)(COD)Cl] claim 4 , Ir(I)(COD)(acac) and Ir(III)(CH)(acac).6. The composition of claim 3 , wherein said solvent comprises 1 claim 3 ,2-dichloroethane claim 3 , tetrahydrofuran claim 3 , dimethoxyethane claim 3 , toluene claim 3 , EtOAc and i-PrOH.7. The composition of claim 3 , wherein said chemical ligand is 4-Ethynylanisole.8. The composition of is administered to a subject in need thereof in order to prevent and/or treat the cancer or tumor in said subject.9. The composition of claim 8 , wherein said cancer or tumor comprises hepatoma claim 8 , breast claim 8 , oesophageal claim 8 , colorectal and lung carcinoma.11. The method of claim 10 , wherein said transition metal-catalyzed alkynylation comprising using an iridium-based catalyst.12. The method of claim 11 , wherein said iridium-based catalyst comprises Ir(I)(COD)Cl claim 11 , [Ir(I)(COD)Cl] claim 11 , Ir(I)(COD)(acac) and Ir(III)(CH)(acac).13. The method of claim 10 , wherein said chemical ligand is 4-Ethynylanisole.14. The method of claim 10 , wherein said ...

Asymetric synthesis of norcantharidin analougus by alkynylation of oxabenzonorbornadienes and their anticancer activities

The present invention relates to a type of norcantharidin analogues and a method to synthesis such norcantharidin analogues by transition metal-catalyzed alkynylation of 7-oxabenzonorbornadienes. The present invention also relates to the use of such norcantharidin analogues in manufacture of a medicament for the treatment of cancer tumors.

N-TYPE SILICON SOLAR CELL WITH CONTACT/PROTECTION STRUCTURES

A solar cell is formed on an n-type semiconductor substrate having a p+ emitter layer by forming spaced-apart contact/protection structures on the emitter layer, depositing a blanket dielectric passivation layer over the substrate's upper surface, utilizing laser ablation to form contact openings through the dielectric layer that expose corresponding contact/protection structures, and then forming metal gridlines on the upper surface of the dielectric layer that are electrically connected to the contact structures by way of metal via structures extending through associated contact openings. The contact/protection structures serve both as protection against substrate damage during the contact opening formation process (i.e., to prevent damage of the p+ emitter layer caused by the required high energy laser pulses), and also serve as optional suicide sources that facilitate optimal contact between the metal gridlines and the p+ emitter layer. 1. A solar cell comprising:a semiconductor substrate having an upper surface and including a body layer and an emitter layer disposed between the upper surface and the body layer;a plurality of spaced-apart contact structures disposed over first portions of the upper surface, each of the plurality of spaced-apart contact structures having a minimum lateral dimension;a dielectric passivation layer disposed over the upper surface such that the dielectric passivation layer is disposed on the plurality of spaced-apart contact structures and on second portions of the upper surface disposed between the plurality of spaced-apart contact structures;a plurality of metal gridlines disposed on an upper surface of the passivation layer; anda plurality of metal via structures extending through associated openings defined in the passivation layer such that each metal via structure electrically connects an associated metal gridline of the plurality of metal gridlines and an associated contact structure of the plurality of contact structures, ...

ANTIBODIES AND CONJUGATES THAT TARGET MISFOLDED PRION PROTEIN

Human prion protein, PrP, selectively presents the epitope MDEYSNQNN (SEQ ID No. 14) when PrP misfolds. The misfolded form of human PrP is associated with various disease states. The present invention provides an antibody useful to detect and treat such diseases, including cancer such as ovarian cancer and lymphomas, and transmissible spongiform encephalopathies such as CJD. Also provided is an immunoconjugate in which the antibody is conjugated with urease as cytotoxin. 2. An antibody according to claim 1 , wherein the light chain variable region comprises SEQ ID No. 7.3. An antibody according to or claim 1 , wherein the heavy chain variable region comprises SEQ ID No. 8.4. An antibody according to claim 1 , wherein the light chain comprises SEQ ID No. 9.5. An antibody according to or claim 1 , wherein the heavy chain comprises SEQ ID No. 10.65. A fragment of the antibody according to - claim 1 , wherein the fragment binds selectively to the epitope MDEYSNQNN or a part thereof that (1) comprises at least 5 contiguous residues and (2) retains binding affinity for the antibody according to .75. An immunoconjugate comprising the antibody of - or the fragment of and claim 1 , conjugated therewith claim 1 , a toxin.85. An immunoconjugate comprising urease and claim 1 , conjugated therewith claim 1 , the antibody of - or the fragment of .95. An immunoconjugate comprising the antibody of - or the fragment of and claim 1 , conjugated therewith claim 1 , a detectable label.108. A pharmaceutical composition comprising an antibody claims 1 , fragment or immunoconjugate according to any one of - claims 1 , and a pharmaceutically acceptable carrier.118. The use of an antibody claims 1 , fragment or immunoconjugate according to any one of - for the treatment of a disorder mediated by misfolded human PrP.12. The use according to claim 11 , for the treatment of cancer or CJD.13. The use according to claim 12 , for the treatment of cancer.14. The use according to claim 13 , for the ...

Method for the Preparation of Iodoalkanes

The present invention relates to an atom economic procedure of preparing iodoalkanes by hydroiodination of alkenes. In particular the present method features the generation of anhydrous hydrogen iodide from atomic hydrogen and iodine in situ by using transition metal precursor and phosphine ligandcatalyst.

VEGFR-2 CAR IMMUNE CELLS TO TREAT CANCERS

Compositions and methods for treating cancer in humans are provided using CARs. The invention includes engineered CARs (chimeric receptor antigens) and genetically modified immune cells that express such a CAR with a high affinity for VEGFR. More specifically, the cells are CAR-T cells recognizing VEGFR-2 on solid tumors, uses thereof, compositions thereof and methods of making. The invention includes therapeutic methods to treat VEGFR-2 dependent cancers targeting tumor angiogenesis. 1. A chimeric antigen receptor (CAR) that binds to VEGFR-2 , an epitope or fragment thereof , or a variant thereof.2. The CAR of claim 1 , wherein said CAR comprises a single domain antibody or a fragment thereof for binding to VEGFR-2.3. The CAR of claim 2 , wherein said single domain antibody or fragment thereof is of the species Camelidae.4. The CAR of claim 3 , wherein said CAR binds to an epitope of VEGFR-25. The CAR of claim 4 , wherein said CAR binds to an epitope found in SEQ ID NO:1.6. The CAR of any claim 1 , wherein said CAR comprises a complementarity determining region (CDR) 1; a CDR2; and/or a CDR3 claim 1 , wherein at least one of CDR1 claim 1 , CDR2 and CDR3 bind to VEGFR-2.7. The CAR of claim 1 , wherein the CAR comprises at least one CDR having a sequence selected from the group consisting of SYAMG claim 1 , AISWSDDSTYYANSVKG claim 1 , HKSLQRPDEYTY and a sequence at least 70% identical thereto which binds VEGFR2.8. The CAR of claim 1 , comprising the sequence of SEQ ID NO:78 or a sequence at least 90% identical thereto.9. The CAR of claim 1 , comprising a spacer molecule claim 1 , a transmembrane region and one or more cell signaling domains selected from the group consisting of a human CD8-alpha protein claim 1 , a human CD28 protein claim 1 , a human CD3-zeta protein claim 1 , a human FcRy protein claim 1 , a CD27 protein claim 1 , an OX40 protein claim 1 , a human 4-IBB protein claim 1 , modified versions of any of the foregoing claim 1 , and any combination of the ...

ANTI-VEGFR-2 UREASE CONJUGATES

A conjugate comprising an anti-VEGFR-2 antibody moiety conjugated to a urease moiety is described. 1. A conjugate comprising an anti-VEGFR-2 antibody moiety conjugated to a urease moiety.2. The conjugate of claim 1 , wherein the antibody moiety is conjugate to the urease moiety via a cross-linker claim 1 , optionally wherein the cross-linker is relatively long and flexible.3. The conjugate of claim 2 , wherein the cross-linker is a (PEG)class cross-linker selected from SM(PEG)or BM(PEG).4. The conjugate of claim 1 , wherein the conjugate has a conjugation ratio selected from about 1 claim 1 , about 2 claim 1 , about 3 claim 1 , about 4 claim 1 , about 5 claim 1 , about 6 claim 1 , about 7 claim 1 , about 8 claim 1 , about 9 claim 1 , about 10 claim 1 , about 11 claim 1 , or about 12 antibody moieties per urease moiety.5. The conjugate of claim 4 , wherein the conjugation ratio is up to about 3.3.6. The conjugate of claim 4 , wherein the conjugation ratio is about 3.3.7. The conjugate of claim 1 , wherein the urease moiety is a Jack bean urease.8. The conjugate of claim 1 , wherein the antibody moiety is a single domain antibody or fragment thereof or variant thereof.9. The conjugate of claim 8 , wherein the antibody comprises at least one CDR having a sequence selected from the group consisting of SYAMG claim 8 , AISWSDDSTYYANSVKG claim 8 , HKSLQRPDEYTY and a sequence at least 70% identical thereto which binds VEGFR2.10. The conjugate of claim 8 , wherein the single domain antibody or fragment thereof comprises or consists of a sequence selected from the group consisting of SEQ ID NO:2-30 claim 8 , fragments thereof claim 8 , and variants thereof.11. The conjugate of claim 10 , wherein the variants have at least 70% claim 10 , 75% claim 10 , 80% claim 10 , 85% claim 10 , 86% claim 10 , 87% claim 10 , 88% claim 10 , 89% claim 10 , 90% claim 10 , 910% claim 10 , 92% claim 10 , 93% claim 10 , 94% claim 10 , 95% claim 10 , 97% claim 10 , 98% claim 10 , or 99% sequence ...

VEGFR2 ANTIBODIES

Single domain anti-VEGFR-2 antibodies and fragments thereof and variants thereof and uses thereof, for example, for use to inhibit/decrease angiogenesis and induce tumor regression. 1. A polypeptide comprising the sequence of any one of SEQ ID NO:2-30 or a fragment or variant thereof.2. The polypeptide of claim 1 , wherein said polypeptide specifically binds to VEGFR-2.3. The polypeptide of claim 2 , wherein the polypeptide binds to an epitope of VEGFR-2.4. The polypeptide of claim 1 , wherein the fragments or variants have at least 85% claim 1 , at least 86% claim 1 , at least 87% claim 1 , at least 88% claim 1 , at least 89% claim 1 , at least 90% claim 1 , at least 91% claim 1 , at least 92% claim 1 , at least 93% claim 1 , at least 94% claim 1 , at least 95% claim 1 , at least 96% claim 1 , at least 97% claim 1 , at least 98% claim 1 , at least 99% claim 1 , or 100% identity to any one of SEQ ID NO:2-30.5. The polypeptide of claim 1 , wherein said polypeptide is a single domain antibody.6. The polypeptide of claim 4 , wherein said polypeptide is selected from the group consisting of:a polypeptide comprising the sequence of SEQ ID NO:2 or fragments or variants thereof having more than 93% identity to SEQ ID NO:2, or fragments or variants thereof having more than 85% identity to SEQ ID NO:2, wherein the fragments or variants thereof comprise more than 116 amino acid residues;a polypeptide comprising the sequence of SEQ ID NO: 11 or fragments or variants thereof having more than 77% identity to SEQ ID NO: 11;a polypeptide comprising the sequence of SEQ ID NO: 19 or fragments or variants thereof having more than 88% identity to SEQ ID NO: 19;a polypeptide comprising the sequence of SEQ ID NO:6 or fragments or variants thereof having more than 86% identity to SEQ ID NO:6;a polypeptide comprising the sequence of SEQ ID NO:25 or fragments or variants thereof having more than 80% identity to SEQ ID NO:25;a polypeptide comprising the sequence of SEQ ID NO:26 or fragments ...

MATERIAL CLEANING DEVICE AND COOKING APPLIANCE

The present disclosure provides a material cleaning device and a cooking appliance: The device includes a cleaning cavity, a material transport pipe, a cleaning inlet pipe and a cleaning and sealing assembly. The upper part of the cleaning cavity is provided with a material feeding port and an air inlet; the air inlet is used for transporting an air flow to the cleaning cavity to assist in material discharging; the cleaning inlet pipe is able to be connected to a water source and an air source, the cleaning and sealing assembly is provided at a material discharging port and is connected to the cleaning inlet pipe so as to open or close the material discharging port under the driving of the cleaning inlet pipe; and the cleaning and sealing assembly is provided with a transport hole in communication with an output end of the cleaning inlet pipe and the inner space of the cleaning cavity. 1. A material cleaning device for a cooking appliance , comprising:a cleaning cavity, wherein an upper part of the cleaning cavity is provided with a material feeding port and an air inlet, a bottom of the cleaning cavity is provided with a material discharging port, and the air inlet is used for transporting air flow to the cleaning cavity to assist material discharging;a material transport pipe communicated with the material feeding port and used for transporting materials to be cleaned to the cleaning cavity;a cleaning inlet pipe, wherein an input end of the cleaning inlet pipe is able to be connected to a water source and an air source, and an output end of the cleaning inlet pipe extends into the cleaning cavity and is able to move up and down relative to the cleaning cavity; anda cleaning and sealing assembly provided at the material discharging port and connected to the output end of the cleaning inlet pipe so as to open or close the material discharging port under driving of the cleaning inlet pipe, and the cleaning and sealing assembly is provided with a transport hole ...

COMBINED ELECTROMAGNETIC SHIELD AND THERMAL MANAGEMENT DEVICE

Various EMI shields with thermal management capabilities are disclosed. In one aspect, an EMI shield is provided that includes a thermal spreader plate adapted to be seated on and convey heat from an electromagnetic emissions generating component. The thermal spreader plate has a first material composition and a shield effectiveness that is absorption dominant to electromagnetic waves at a given electromagnetic emissions frequency. The EMI shield also includes a shell to cover and reflect electromagnetic emissions from the electromagnetic emissions generating component. The shell has a second material composition different than the first material composition and a shield effectiveness that is reflection dominant to electromagnetic waves at the given electromagnetic emissions frequency. 1. An EMI shield , comprising:a thermal spreader plate adapted to be seated on and convey heat from an electromagnetic emissions generating component, the thermal spreader plate having a first material composition and a shield effectiveness that is absorption dominant to electromagnetic waves at a given electromagnetic emissions frequency; anda shell to cover and reflect electromagnetic emissions from the electromagnetic emissions generating component, the shell having a second material composition different than the first material composition and a shield effectiveness that is reflection dominant to electromagnetic waves at the given electromagnetic emissions frequency.2. The EMI shield of claim 1 , comprising a gap between the spreader plate and the shell.3. The EMI shield of claim 2 , comprising plural posts positioned between the spreader plate and the shell to transfer heat.4. The EMI shield of claim 1 , wherein the shell comprises a first metal jacketed by a second metal.5. The EMI shield of claim 1 , comprising a first thermal interface material between the thermal spreader plate and the shell.6. An apparatus claim 1 , comprising:a substrate;an electromagnetic emissions ...

Cooking Appliance

A cooking appliance includes a base, a cover body pivotally mounted at the base, a pivot spring provided at a pivot connection member between the base and the cover body, and an attraction assembly including a first attraction member provided at the base and a second attraction member provided at the cover body. The first attraction member and the second attraction member are configured to attract each other to lock the cover body to the base. 121.-. (canceled)22. A cooking appliance comprising:a base;a cover body pivotally mounted at the base;a pivot spring provided at a pivot connection member between the base and the cover body; andan attraction assembly including a first attraction member provided at the base and a second attraction member provided at the cover body, the first attraction member and the second attraction member being configured to attract each other to lock the cover body to the base.23. The cooking appliance of claim 22 , wherein in a closed state of the cover body claim 22 , with respect to a pivot hinge point between the cover body and the base claim 22 , a sum of a gravity center torque M1 of the cover body and an attraction torque M3 of the first attraction member and the second attraction member is larger than a return torque M2 of the pivot spring.24. The cooking appliance of claim 23 , wherein M3−(M2−M1)>1 Nm and M3−(M2−M1)<15 Nm.25. The cooking appliance of claim 22 , wherein the attraction assembly includes a magnetic attraction lock assembly provided at a distal end of cooking appliance with respect to the pivot connection member.26. The cooking appliance of claim 25 , wherein the magnetic attraction lock assembly includes:a magnet as one of the first attraction member the second attraction member; andan iron core rod as another one of the first attraction member and the second attraction member.27. The cooking appliance of claim 26 , further comprising:a shift lever mechanism including a shift lever switch and configured to, when ...

COMBINED ELECTROMAGNETIC SHIELD AND THERMAL MANAGEMENT DEVICE

Various EMI shields with thermal management capabilities are disclosed. In one aspect, an EMI shield is provided that includes a thermal spreader plate adapted to be seated on and convey heat from an electromagnetic emissions generating component. The thermal spreader plate has a first material composition and a shield effectiveness that is absorption dominant to electromagnetic waves at a given electromagnetic emissions frequency. The EMI shield also includes a shell to cover and reflect electromagnetic emissions from the electromagnetic emissions generating component. The shell has a second material composition different than the first material composition and a shield effectiveness that is reflection dominant to electromagnetic waves at the given electromagnetic emissions frequency. 1. An EMI shield , comprising:a thermal spreader plate adapted to be seated on and convey heat from an electromagnetic emissions generating component positioned on a substrate having a ground pathway, the thermal spreader plate having a first material composition and a shield effectiveness that is absorption dominant to electromagnetic waves at a given electromagnetic emissions frequency; anda shell to cover and reflect electromagnetic emissions from the electromagnetic emissions generating component, the shell having a second material composition different than the first material composition and a shield effectiveness that is reflection dominant to electromagnetic waves at the given electromagnetic emissions frequency, the shell having sidewalls surrounding the electromagnetic emissions generating component laterally and extending to the substrate when the EMI shield is seated on the electromagnetic emissions generating component, the shell being operable to connect to the ground pathway.2. The EMI shield of claim 1 , comprising a gap between the spreader plate and the shell.3. The EMI shield of claim 2 , comprising plural posts positioned between the spreader plate and the shell to ...

Broadband and Omnidirectional Polymer Antireflection Coatings

A method for generating antireflective coatings for polymeric substrates using a deposition process and/or a dissolving process can provide a coating onto the outer surface of the substrate. Some embodiments can include a GLAD generated fluoropolymer coating or a co-evaporated fluoropolymer coating on a substrate that may achieve ultralow refractive index as well as improved adhesion and durability properties on polymeric substrates. In some embodiments, the deposition process is performed such that a fluoropolymer can be evaporated to form chain fragments of the fluoropolymer. The chain fragments diffused into the substrate can subsequently re-polymerize, interlocking with the polymer chains of the substrate. In some embodiments, the co-evaporation process can form a nanoporous polymer chain scaffold of the fluoropolymer, from which a sacrificial material can be dissolved out. The formed coating can be a multilayer or continuously-graded antireflective coating that has strong adhesion with the substrate.

Deuterium-Modified Brigatinib Derivatives, Pharmaceutical Compositions Comprising Same, And Use Thereof

The present invention relates to the field of pharmaceutical chemistry, and relates to a deuterium-modified Brigatinib derivative, preparation method thereof, pharmaceutical composition containing the same and the uses of the deuterium-modified Brigatinib derivative and the pharmaceutical composition thereof in preparing a medicament for treating the disease mediated by anaplastic lymphoma kinase. The deuterium-modified Brigatinib derivative of the present invention has an excellent inhibitory activity on anaplastic lymphoma kinase and has better pharmacodynamic or pharmacokinetic properties relative to Brigatinib.

PALLADIUM/SILVER CO-CATALYZED TANDEM REACTIONS SYNTHESIS OF PHENYLACETOPHENONE DERIVATIVES BY OXABENZONORBORNADIENES WITH TERMINAL ALKYNES AND THEIR ANTI-TUMOR OR ANTI-CANCER ACTIVITIES

This invention relates to the quick and efficient synthesis of anti-tumor or anti-cancer compounds. More particularly, it relates to the quick and efficient synthesis of anti-tumor or anti-cancer compounds comprising phenylacetophenone derivatives using oxabenzonorbornadienes with terminal alkynes 1. Anti-tumor or anti-cancer compounds for treating cancer synthesized via steps comprising:adding a Pd complex, a ligand and a first solvent in a first noble gas atmosphere to form a first mixture;stirring the first mixture at a first given temperature for a first given time duration;{'sub': 3', '3, 'adding CFSOAg to the stirred first mixture to form a second mixture;'}stirring the second mixture for a second given time duration;adding an oxobenzonorbornadienes derivative and a second solvent to the stirred second mixture to form a third mixture;stirring the third mixture for a third given time duration;adding a terminal alkynes to the third mixture to form a fourth mixture;stirring the fourth mixture in a second noble gas atmosphere at a second given temperature until the complete consumption of the oxobenzonorbornadienes derivative;evaporating the solvents in the stirred fourth mixture to obtain residue; andpurifying the residue to obtain the anti-tumor or anti-cancer compounds.3. The anti-tumor or anti-cancer compounds according to comprising:2-(naphthalen-2-yl)-1-phenylethanone;1-(4-methoxyphenyl)-2-(naphthalen-2-yl) ethanone;1-(2-methoxyphenyl)-2-(naphthalen-2-yl) ethanone;1-(3-methoxyphenyl)-2-(naphthalen-2-yl) ethanone;1-(3,5-dimethoxyphenyl)-2-(naphthalen-2-yl) ethanone;1-(4-fluorophenyl)-2-(naphthalen-2-yl) ethanone;2-(naphthalen-2-yl)-1-(4-(trifluoromethoxy) phenyl) ethanone;1-(4-bromophenyl)-2-(naphthalen-2-yl) ethanone;2-(naphthalen-2-yl)-1-(p-tolyl) ethanone;2-(naphthalen-2-yl)-1-(4-phenoxyphenyl) ethanone;1-(4-(hydroxymethyl)phenyl)-2-(naphthalen-2-yl) ethanone;2-(naphthalen-2-yl)-1-(4-(trifluoromethyl) phenyl) ethanone;4-(2-(naphthalen-2-yl) acetyl) ...

RESTORING FUNCTION OF TUMOUR ACIDIFIED T CELLS

Methods and compositions to restore function to acidified T cells are provided. The methods comprise administering urease to the T cells. Compositions comprise urease. 1. A method for decreasing PD-L1 expression on a cancer cell , the method comprising:administering urease to the cancer cell.2. The method of claim 1 , wherein the cancer cell is acid sensitive.3. The method of claim 1 , wherein the urease is administered in an amount sufficient to increase the pH in the vicinity of the cancer cell to physiological levels.4. The method of claim 3 , wherein the pH is increased to 7.2.5. The method of claim 1 , wherein the urease is administered in an amount that increases production of cytokines by surrounding T cells acidified with lactate produced by the cancer cell.6. The method of claim 5 , wherein the cytokines comprise IL-2.7. The method of claim 1 , wherein the urease is administered in an amount that does not cause significant death or harm to surrounding T cells acidified with lactate produced by the cancer cell.8. The method of claim 7 , wherein the T cells express PD-1 claim 7 , optionally at higher than normal levels compared to a non-acidified T cell and wherein the urease inhibits PD-1 expression and/or activation.9. The method of claim 1 , wherein the urease is conjugated to an antibody specific for CEACAM6.10. The method of claim 9 , wherein the antibody is an AFAIKL2 antibody or a 2A3 antibody.11. The method of claim 1 , further comprising administering an active agent selected from a PD-1 inhibitor claim 1 , a chemotherapeutic agent claim 1 , radiation claim 1 , a hormone claim 1 , a cytokine and combinations thereof to said cancer cell.12. A method for decreasing PD-L1 expression on a cancer cell in a solid tumor claim 1 , the method comprising administering urease to the solid tumor.13. The method of claim 12 , wherein the solid tumor is CEACAM6+ and/or PD-L1+.14. The method of claim 13 , wherein said urease reactivates acidified T cells surrounding ...

Organic ferroelectric memory cells

This invention proposes to make memory using organic materials. The basic structure of the memory cell is a field effect organic transistor using a ferroelectric thin film polymer as gate dielectric. By controlling the gate voltage to polarize the thin film ferroelectric polymer polarized in either an “up” or “down” state, the source-drain current can be controlled between two different values under the same source-drain voltage. The source-drain current thus can be used to represent either a “0” or “1” state. The organic thin film transistor can be made from poly(phenylenes), thiophene oligomers, pentacene, polythiophene, perfluoro copper phthalocyanine or other organic thin films. The ferroelectric thin film can be poly(vinylidene fluoride) (PVDF), poly(vinyldiene-trifluoroethylene) (P(VDF-TrFE)) copolymers, odd-numbered nylons, cyanopolymers, polyureas, or other ferroelectric thin films. As the deposition of these organic thin films can be done at temperatures below 200° C., the memory cell can be made on many kinds of substrates including plastics.

Organic ferroelectric memory cells

This invention proposes to make memory using organic materials. The basic structure of the memory cell is a field effect organic transistor using a ferroelectric thin film polymer as gate dielectric. By controlling the gate voltage to polarize the thin film ferroelectric polymer polarized in either an “up” or “down” state, the source-drain current can be controlled between two different values under the same source-drain voltage. The source-drain current thus can be used to represent either a “0” or “1” state. The organic thin film transistor can be made from poly(phenylenes), thiophene oligomers, pentacene, polythiophene, perfluoro copper phthalocyanine or other organic thin films. The ferroelectric thin film can be poly(vinylidene fluoride) (PVDF), poly(vinyldiene-trifluoroethylene) (P(VDF-TrFE)) copolymers, odd-numbered nylons, cyanopolymers, polyureas, or other ferroelectric thin films. As the deposition of these organic thin films can be done at temperatures below 200° C., the memory cell can be made on many kinds of substrates including plastics.

NEGATIVE PRESSURE WOUND TREATMENT SYSTEM HAVING A BUFFER UNIT

Negative pressure wound therapy system with a buffering unit

Silicon-containing compound for resistance to hepatitis C virus infection

The present invention provides a silicon-containing compound for resistance to hepatitis c virus infection, and in particular provides a compound represented by formula I, or a pharmaceutically acceptable salt, or a tautomer, or a stereoisomer, or a deuterated compound thereof and mixture among them, a preparation process therefor, and a pharmaceutical composition comprising the same. The present application also provides a use of the compound, or a pharmaceutically acceptable salt, or a tautomer, or a stereoisomer, or a deuterated compound thereof and mixture among them, and a pharmaceutical composition comprising the same in treatment of hepatitis c virus infection.

Interdigitated back contact silicon solar cells with laser ablated grooves

Interdigitated back contact (IBC) solar cells are produced by depositing spaced-apart parallel pads of a first dopant bearing material (e.g., boron) on a substrate, heating the substrate to both diffuse the first dopant into corresponding first (e.g., p+) diffusion regions and to form diffusion barriers (e.g., borosilicate glass) over the first diffusion regions, and then disposing the substrate in an atmosphere containing a second dopant (e.g., phosphorus) such that the second dopant diffuses through exposed surface areas of the substrate to form second (e.g., n+) diffusion regions between the first (p+) diffusion regions (the diffusion barriers prevent the second dopant from diffusion into the first (p+) diffusion regions). The substrate material along each interface between adjacent first (p+) and second (n+) diffusion regions is then removed (e.g., using laser ablation) such that elongated grooves, which extend deeper into the substrate than the diffused dopant, are formed between adjacent diffusion regions.

Solar cell metallization using inline electroless plating

Inline methods for forming a photovoltaic cell electrode structure, wherein the photovoltaic cell includes a semiconductor substrate having a passivation layer thereon, includes providing a plurality of contact openings through the passivation layer to the semiconductor substrate, selectively plating a contact metal into the plurality of contact openings by printing electroless plating solution into the plurality of contact openings to deposit the contact metal, depositing a metal containing material on the deposited contact metal, and firing the deposited contact metal and the deposited metal containing material. The metal containing material may include a paste containing a silver or silver alloy along with a glass frit and is substantially free to completely free of lead. The methods may also use light activation of the passivation layer or use seed layers to assist in the plating.

N-type silicon solar cell with contact/protection structures

A solar cell is formed on an n-type semiconductor substrate having a p+ emitter layer by forming spaced-apart contact/protection structures on the emitter layer, depositing a blanket dielectric passivation layer over the substrate's upper surface, utilizing laser ablation to form contact openings through the dielectric layer that expose corresponding contact/protection structures, and then forming metal gridlines on the upper surface of the dielectric layer that are electrically connected to the contact structures by way of metal via structures extending through associated contact openings. The contact/protection structures serve both as protection against substrate damage during the contact opening formation process (i.e., to prevent damage of the p+ emitter layer caused by the required high energy laser pulses), and also serve as optional silicide sources that facilitate optimal contact between the metal gridlines and the p+ emitter layer.

Vectors, cells and processes for pyrimidine deoxyribonucleosides production

Novel DNA constructs and host cells comprising the same are disclosed. DNA constructs comprise a transcription unit (e.g. operon) comprising DNA sequences encoding for ribonucleotide reductase and thioredoxin or a uridine kinase gene and/or a dCTP deaminase gene. In preferred embodiments the constructs comprising DNA sequences encoding for ribonucleotide reductase and thioredoxin further comprise DNA sequences encoding for thymidylate synthase and/or transcription units comprising sequences encoding for uridine kinase preferably together with dCTP deaminase. In particularly preferred embodiments, the host cells comprise constructs having all of the above characteristics wherein the host cell displays repressed or no uracil DNA glycosylase activity. This may be achieved by removal of the host cell ung gene. Use of host cells in the manufacture of pyrimidine deoxyribonucleotides e.g. thymidine is also disclosed.

Actuator for negative pressure wound treatment system, has liquid limiter mounted in part of intake extension, and outlet tube connected to outlet connection of pump head, where part of extension is connected to fluid connection of shell

The actuator has a pump head (20) made of a biocompatible material and mounted in a shell (10). An intake extension (30) i.e. manifold, is respectively connected to an intake connection (21) of the pump head and a fluid connection (11) of the shell. A liquid limiter i.e. spiral tube (33), is mounted in a part of the intake extension, where the part of the intake extension is connected to the fluid connection of the shell. An outlet tube (40) is connected to an outlet connection (22) of the pump head.

Antibody-urease conjugates for therapeutic purposes

Pharmaceutical compositions comprising antibody-urease conjugates and substantially free of unconjugated urease are disclosed. These compositions are prepared by a method that does not require chromatographic purification. These pharmaceutical compositions have utility in the treatment of cancer by antibody-directed enzyme prodrug therapy wherein the urease converts endogenous urea into ammonia in situ to induce cytotoxicity.

Feedback control method for wound treating system to treat wound of user in e.g. hospital, by negative pressure to heal wound, involves sending detection results to determine whether operation mode is stopped

The method involves creating a negative pressure environment in an opening (511) of a dressing unit (50) of a wound treating system and a positive pressure environment in a collection bag of the system. A positive pressure detection procedure and a negative pressure detection procedure are conducted in the positive pressure environment and the negative pressure environment, respectively. Detection results are sent to determine whether an operation mode is stopped. An independent claim is also included for a system for treating a wound by negative pressure.

Large dimension, flexible piezoelectric ceramic tapes and methods to make same

A flexible detection/test tape includes a first flexible conductive layer, and a second flexible conductive layer positioned opposite the first conductive layer. A plurality of at least one of sensors, actuators or transducers are positioned between and are bonded to the first flexible conductive layer and the second flexible conductive layer. An insulative material is inserted around the plurality of at least one of the sensors, actuators or transducers. An electrical contact network connects to the first flexible conductive layer and the second flexible conductive layer, whereby power and control signals are provided to the flexible detection/test tape. In an alternative embodiment, a method for producing a detection/test tape includes depositing a material onto a surface of at least one first substrate to form a plurality of element structures. Electrodes are deposited on a surface of each of the plurality of element structures, and the element structures are bonded to a second substrate, where the second substrate is conductive or has a conductive layer, and the second substrate is carried on a carrier plate. The at least one first substrate is removed from the element structures and second side electrodes are deposited on a second surface of each of the plurality of element structures. An insulative material is inserted around the element structures to electrically isolate the two substrates used to bond the element structures. A second side of the element structures is then bonded to another substrate, where the other substrate is conductive or has a conductive layer. Thereafter, the carrier plate carrying the second substrate is removed.

Vegfr-2 car immune cells to treat cancers

Compositions and methods for treating cancer in humans are provided using CARs. The invention includes engineered CARs (chimeric receptor antigens) and genetically modified immune cells that express such a CAR with a high affinity for VEGFR. More specifically, the cells are CAR-T cells recognizing VEGFR-2 on solid tumors, uses thereof, compositions thereof and methods of making. The invention includes therapeutic methods to treat VEGFR-2 dependent cancers targeting tumor angiogenesis. A chimeric antigen receptor (CAR) that binds to VEGFR-2, an epitope or fragment thereof, or a variant thereof.

Crystal refining technologies by controlled crystallization

A method is provided for making large, uniform and individual crystals from aqueous solutions including the steps of obtaining a concentrated aqueous solution by means of evaporation; rapidly cooling the solution from a post-evaporation high temperature to a first lower temperature, wherein the first lower temperature is lower than the post-evaporation high temperature and further wherein the first lower temperature is an isothermal crystallization temperature of said solution; generating a batch of initial nuclei by inducing nucleation at the first lower temperature and starting crystal growth; uniformly spreading the initial nuclei into a bulk solution; maintaining simultaneous and rapid growth of crystals from the nuclei at the first lower temperature for a predetermined length of time; continuing the growth of the crystals to produce large, uniform and individual crystals for a predetermined length of time at a temperature that varies gradually from between a first lower temperature to a second lower temperature, wherein the second lower temperature is a temperature lower than the first lower temperature and further wherein the second lower temperature is an end temperature of crystallization; and recovering the large, uniform and individual crystals. Parameters and a system for producing lactose monohydrate crystals using the method are also provided.

Preparation method of a tile with solid pores as decoration and its product.

Se provee un método para la preparación de mosaicos de cerámica con poros sólidos como decoración y su producto. El método incluye los siguientes pasos: preparar un material fino, que incluye un material de cara y un material de base; distribuir y prensar en seco el material fino para formar un cuerpo moldeado; secar el cuerpo moldeado; calcinar el cuerpo para formar un producto semiacabado; tratar la superficie del producto semiacabado para formar un producto acabado; la preparación del material de cara incluye la preparación de un material de cara con patrón, por lo menos una clase del cual está provisto como un formador de poros; la formación del cuerpo moldeado incluye: distribuir y prensar en seco el formado de poros con el material de cara y el material de base; y la calcinación del cuerpo moldeado incluye calcinar el material de cara bajo la temperatura de calcinación, a una escala de entre 1100 y 1250ºC, para formar poros (10) sólidos, fisuras (11) y/o texturas.

Anti-vegfr-2 urease conjugates

Antibody-urease conjugates having therapeutic utility are provided. More specifically, described herein are anti-VEGFR-2 antibody-urease conjugates for the treatment of solid tumors. A conjugate comprising an anti-VEGFR-2 antibody moiety conjugated to a urease moiety is described. Compositions and methods are also described for the treatment of VEGFR-2 dependent tumors, incorporating the antibody-urease conjugates described herein.

Metallization Contact Structures and Methods for Forming Multiple-Layer Electrode Structures for Silicon Solar Cells

Metallization contact structures and methods for forming a multiple-layer electrode structure on a solar cell include depositing a conductive contact layer on a semiconductor substrate and depositing a metal bearing ink onto a portion of the conductive contact layer, wherein the exposed portions of the conductive contact layer are adjacent to the metal bearing ink. The conductive contact layer is patterned by removing the exposed portions of the conductive contact layer from the semiconductor substrate. The metal bearing ink is aligned with one or more openings in a dielectric layer of the semiconductor substrate and with unexposed portions of the conductive contact layer. The unexposed portions of the conductive contact layer are interposed between the metal bearing ink and the dielectric layer of the semiconductor substrate such that the conductive contact layer pattern is aligned with metal bearing ink. The semiconductor substrate is thermally processed to form a current carrying metal gridline by sintering the metal bearing ink.

Continuous crystallization system with controlled nucleation for milk fat fractionation

Obstacle clearing device for soldier mine

本实用新型提供了一种排步兵雷清障装置，包括抛射装置、发射架、高能导爆索、启爆装置以及携带装置，所述抛射装置设置在发射架上，抛射装置的后面连接高能导爆索，高能导爆索的最末端设置有引爆装置，所述抛射装置、发射架、高能导爆索和引爆装置装在携带装置内，所述启爆装置通过无线遥控或有线方式使所述引爆装置启爆。该排步兵雷清障装置体积小，集成为一个背包，携带方便，单人可携带，而且操作快速便捷，单人操作，瞬间可在反步兵雷场形成安全通道供人员通过。

Negative pressure wound therapy system with a buffering unit

Backlight module and its optical lens

Feedback control method of negative pressure wound care system and negative pressure wound care system

Restoring function of tumour acidified t cells

Spreadsheet formula translation of server calculation rules

Architecture includes for translating server calculations into client application formulas. The architecture determines dependencies, performs formulae translation, and processes data retrieval queries using the translated formulae. In one implementation, the architecture translates performance management server calculations into spreadsheet application formulas so that the impact of changes can be reflected immediately. Moreover, this technique does not require updating and querying of the performance management server. An algorithm is provided that allows translation of the backend formula (e.g., MDX—multidimensional expressions) directly into the spreadsheet application such that the impact on calculated values by an input change can be reflected instantaneously in the sheet.

Automatic opening and locking device of dewatering tank using carbon dioxide for fruits and vegetables

An automatic opening and locking device of a dewatering tank using carbon dioxide for fruits and vegetables opens, closes and rotates a cover of the tank by hydraulic or air cylinders. The cover(7) is fixed on the tank body(2) by means of jaws(7-2) and clamping grooves(2-1) and is tightened up with the tank body through rotating. The jaws are set on the cover and the clamping grooves are set on the tank body. A cover automatic opening-closing device and a cover automatic screwing device are set between the cover and the tank body.

Texturing multicrystalline silicon

Techniques are disclosed for surface texturing multicrystalline silicon using drop jetting technology to form mask or etch patterns on a surface of a multicrystalline silicon substrate.

Freeze concentration for aqueous solutions

The efficient physical process for freeze concentration of aqueous solutions is based on ice crystal transformation, which results in very rapid growth o f ice crystals and grain-shaped and agglomerated large crystals without inside entrainment, and avoidance of ice scraping for refrigeration to save energy. It comprises, mainly, refrigerating solutions to a supercooled state without ice nucleation, or without ice formation on the heat transfer surface, instantaneously nucleating the supercooled solution to generate fine ice crystals and make the solution concentrated, producing large, grain/sphere- shaped ice crystals at high rate by growth, transformation and agglomeration of ice crystals under environment of well-controlled endo/exothermal balance s. Single-stage and multistage operations can be used for the process and the major steps can be flexibly arranged. Apparatus for performing the process including, mainly, refrigerating heat exchangers, nucleators, filters and multi-function crystallizers are characterized to meet requirements of the process.

Disc player

Actuator for low-pressure wound therapy system utilized for producing low pressure environment in wound and extracting sanies, has outlet tube connected with outlet port of pump head that is made of biocompatible material

The actuator (1) has a pump head made of a biocompatible material and attached in a housing (10). An inflow connection part is formed as a distribution pipe with a passage (31) and connected with the inflow port of the pump head and a fluid port (11) to the housing. A fluid limitation part is formed as a helical pipe and attached in a part of the inflow connection part, where the part of the inflow connection part is connected with the fluid port of the housing. An outlet tube (40) is connected with an outlet port of the pump head. The pump head is removably connected with an external motor.

System and method for monitoring flow rate of regulating valve based on acoustic sensor

Disclosed is a system and method for monitoring flow rate of a regulating valve based on an acoustic sensor. The system includes: the regulating valve installed in a fluid pipeline, the regulating valve including an actuator and a valve body and being a regulating valve calibrated by an experimental platform; the acoustic sensor installed at the regulating valve and configured to collect an acoustic signal of the regulating valve and transmit the acoustic signal to a signal transmission apparatus; the signal transmission apparatus configured to receive the acoustic signal collected by the acoustic sensor and transmit the acoustic signal to an acoustic data analysis platform; and the acoustic data analysis platform configured to monitor flow rate of the regulating valve by receiving the acoustic signal transmitted by the signal transmission apparatus.

Shielded enclosure and socket connector

揭示了一種屏蔽殼體及插座連接器。該插座連接器包括：一絕緣殼體，設有用於容納該插頭連接器的一容納腔；多個連接端子，安裝在該容納腔中；以及一屏蔽殼體，包覆在該絕緣殼體的外部。該屏蔽殼體包括：一第一立壁；與該第一立壁相對之一第二立壁；以及一接口壁，連接在該第一立壁及該第二立壁之間，該接口壁上形成有用於接收一個插頭連接器之一接收開口，該接收開口之一內側邊緣設有通過彎曲向內延伸的多個彈片，該多個彈片包括至少一個截面具有基本上一L形之一第一彈片。該第一彈片包括：一第一臂，從該接口壁的一外邊緣彎曲延伸，並抵靠在該接口壁的一個表面上；以及一第二臂，自該第一臂彎折延伸並朝向該接收開口內部延伸。可以增加該第一彈片對插入至該插座連接器中之該插頭連接器之一彈性接觸力，提高防電磁干擾性能。

Improvement of crystal refining technologies by controlled crystallization

A method is provided for making large, uniform and individual crystals from aqueous solutions including the steps of obtaining a concentrated aqueous solution by means of evaporation; rapidly cooling the solution from a post-evaporation high temperature to a first lower temperature, wherein the first lower temperature is lower than the post-evaporation high temperature and further wherein the first lower temperature is an isothermal crystallization temperature of said solution; generating a batch of initial nuclei by inducing nucleation at the first lower temperature and starting crystal growth; uniformly spreading the initial nuclei into a bulk solution; maintaining simultaneous and rapid growth of crystals from the nuclei at the first lower temperature for a predetermined length of time; continuing the growth of the crystals to produce large, uniform and individual crystals for a predetermined length of time at a temperature that varies gradually from between a first lower temperature to a second lower temperature, wherein the second lower temperature is a temperature lower than the first lower temperature and further wherein the second lower temperature is an end temperature of crystallization; and recovering the large, uniform and individual crystals. Parameters and a system for producing lactose monohydrate crystals using the method are also provided.

Vectors, cells and processes for pyrimidine deoxyribonucleosides production

Novel DNA constructs and host cells comprising the same are disclosed. DNA constructs comprise a transcription unit (eg. operon) comprising DNA sequences encoding for ribonucleotide reductase and thioredoxin or uridine kinase and/or a dCTP deaminase gene. In preferred embodiments the constructs comprising DNA sequences encoding for ribonucleotide reductase and thioredoxin further comprise DNA sequences encoding for thymidylate synthase and/or transcription units comprising sequences encoding for uridine kinase preferably together with dCTP deaminase. In particularly preferred embodiments, the host cells comprise constructs having all of the above characteristics wherein the host cell displays repressed or no uracil DNA glycosylase activity, This may be achieved by the removal of the host cell ung gere, Use of the host cells in the manufacture of pyrimidine deoxyribonucleotides eg. thymidine is also dislosed.

Wounds treatment system, has control unit electrically connected to sensor and actuator, and actuator connected to cushioning unit and collector, where sensor is connected to cushioning unit that is connected between bandage and actuator

The system has a control unit (10) electrically connected to a sensor (20) and an actuator (30), where the actuator is connected to a cushioning unit (50) and a collector (40). The sensor is connected to the cushioning unit that is connected between a bandage (60) and the actuator. The cushioning unit includes a water absorbing layer (51) for draining water. Volume of the water absorbing layer is compressed when the volume of water is increased. The cushioning unit includes an air permeable layer (52) that is connected to the sensor.

Method of manufacturing molded article with decorative pattern

A method of manufacturing a molded article with a decorative pattern thereon, includes the steps of: step ( 10 ), preparing a mold and a mask with a predetermined pattern thereon; step ( 11 ), mounting the mask in the mold; step ( 12 ), spraying ink or paint onto the mask to form a decorative pattern thereon; step ( 13 ), injecting a molten plastic into the mold to form a molded article body; and step ( 14 ), simultaneously transferring the decorative pattern from the mask onto the molded article body, and thus forming a molded article with a decorative pattern thereon.

Interdigitated back contact silicon solar cells with separating grooves

Interdigitated back contact (IBC) solar cells are produced by depositing spaced-apart parallel pads of a first dopant bearing material (e.g., boron) on a substrate, heating the substrate to both diffuse the first dopant into corresponding first (e.g., p+) diffusion regions and to form diffusion barriers (e.g., borosilicate glass) over the first diffusion regions, and then disposing the substrate in an atmosphere containing a second dopant (e.g., phosphorus) such that the second dopant diffuses through exposed surface areas of the substrate to form second (e.g., n+) diffusion regions between the first (p+) diffusion regions (the diffusion barriers prevent the second dopant from diffusion into the first (p+) diffusion regions). The substrate material along each interface between adjacent first (p+) and second (n+) diffusion regions is then removed (e.g., using laser ablation) such that elongated grooves, which extend deeper into the substrate than the diffused dopant, are formed between adjacent diffusion regions.

VECTORS, CELLS AND METHOD FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES

Fluid collector

Vegfr-2 car immune cells to treat cancers

Compositions and methods for treating cancer in humans are provided using CARs. The invention includes engineered CARs (chimeric receptor antigens) and genetically modified immune cells that express such a CAR with a high affinity for VEGFR. More specifically, the cells are CAR-T cells recognizing VEGFR-2 on solid tumors, uses thereof, compositions thereof and methods of making. The invention includes therapeutic methods to treat VEGFR-2 dependent cancers targeting tumor angiogenesis. A chimeric antigen receptor (CAR) that binds to VEGFR-2, an epitope or fragment thereof, or a variant thereof.

Negative pressure wound therapy system with a buffering unit

A negative pressure wound therapy system has a buffering unit 50 connected between an actuator 30 and a wound dressing 60, a sensor 20 connected to the buffering unit 50, a controller 10 connected to the sensor 20 and an actuator 30, and a collector 40 connected to the actuator 30. The buffering unit 50 compensates for negative pressure loss in the wound and resists pressure rise in the wound during slight leakage, dampens the pressure variations from the actuator 30 which may be turned on and off according to the controller 40 and sensor 20, and keeps the actuator 30 from directly operating on the wound to reduce the pain of the patient while lowering the pressure in the wound. The buffering unit 50 may comprise a water-absorbing layer 51, an air-permeating layer 52 which stops liquid flowing into the sensor, and a mesh layer 53 to keep the buffer from collapsing (see figure 3). Under negative pressure the water-absorbing layer 51 compresses and water drains out into the collector. When the actuator is stopped, the water-absorbing layer expands.

Vacuum wound therapy system has actuator that is connected to buffer unit and collector, and sensor that is connected to buffer unit that is connected between wound dressing and actuator

The system has a controller, a sensor, an actuator, a collector (40), a wound dressing (60), and a buffer unit (50). The controller is electrically connected to the sensor and the actuator. The actuator is connected to the buffer unit and the collector. The sensor is connected to the buffer unit that is connected between wound dressing and the actuator.

Ventilative mattress structure

Automatic hub forging die lubricant cleaning device

An automatic hub forging die lubricant cleaning device, comprising a lifting hydraulic cylinder (1), a limiting block (2), a hinge A (3), a hydraulic piston rod (4), a fixed connecting rod (5), a hinge shaft (6), a connecting plate (7), a hydraulic cylinder (8), a hinge B (9) and the like. The device has the advantages that the labor efficiency is improved, the production intensity is reduced, and the generality is strong; and corresponding cleaning scrapers (11) can be set according to the surface shapes of different hub dies (13) and only need to be replaced via general bolt connectors, so that the cost of equipment is reduced.

Cooking appliance

A cooking appliance includes a base, a cover body pivotally mounted at the base, a pivot spring provided at a pivot connection member between the base and the cover body, and an attraction assembly including a first attraction member provided at the base and a second attraction member provided at the cover body. The first attraction member and the second attraction member are configured to attract each other to lock the cover body to the base.

Methods to make bimorph MEMS devices

A bimorph structure is produced by depositing a first material on a first surface of a first substrate to form a first element structure. A second material is deposited onto a surface of a second substrate to form a second element structure. Electrodes are deposited on a surface of each of the first element structure and the second element structure. The first element structure is bonded to a first transfer substrate, and the second element structure is bonded to a second transfer substrate. The first substrate is removed from the first element structure, and the second substrate is removed from the second element structure. Second side electrodes are deposited on a second surface of each of the first element structures and the second element structure. The first element structure and the second element structure are directly bonded to each other. One of the first transfer substrate and the second transfer substrate is then removed, and the surface of the element structure from which one of the transfer substrates has been removed is bonded to a final target substrate. Thereafter, the other transfer substrate is removed, and electrical connections are made.

methods for manufacturing stressed material and shape memory material mems devices

Disclosed is a MEMS device which comprises at least one shape memory material such as a shape memory alloy (SMA) layer and at least one stressed material layer. Examples of such MEMS devices include an actuator, a micropump, a microvalve, or a non-destructive fuse-type connection probe. The device exhibits a variety of improved properties, for example, large deformation ability and high energy density. Also provided is a method of easily fabricating the MEMS device in the form of a cantilever-type or diaphragm-type structure.

Electrical box for electrical equipment

本实用新型公开了电气盒技术领域的用于电气设备的电气盒，包括盒体，所述盒体的两侧均设置有连接板，所述盒体的前后两侧均设置有两组结构相同的线孔，所述盒体的内壁前后两侧均设置有两组结构相同的固定环，且固定环均位于线孔远离盒体外壁的一侧，所述盒体的内壁右侧活动连接有干燥箱，所述盒体的顶部设置有盒盖，所述盒盖的内壁顶部设置有环形槽，所述环形槽的内壁上安装有电机，所述电机的底部动力端连接有扇叶，所述盒体的前后两侧均设置有两组结构相同的散热孔，通过干燥箱内部的干燥剂，可以有效地除去盒体内部的湿气，避免盒体内部腐蚀，影响使用，通过设置有插块，便于取出干燥箱，从而更换掉干燥剂，保证盒体内部的干燥效果。

Structure improvement for the airtight aluminum window

Vegfr-2 car immune cells to treat cancers

Electronic device having connecting mechanism

An electronic device includes a front cover, a rear cover engaging with the front cover, and a connecting mechanism fixed to the front cover. The front cover is secured to the rear cover to cooperatively define a receiving space for receiving a part of the connecting mechanism. The front cover includes a first panel defining two limiting members and a first sidewall extending from a rim of the first panel and defining two latching members. The rear cover includes a second panel defining two protrusions and a second sidewall extending from a rim of the second panel and defining two hook members. The protrusions correspond to the limiting members and are fixed thereto, and the hook members correspond to the latching members and engage therewith.

COLLECTOR FOR NEGATIVE PRESSURE WOUND TREATMENT SYSTEM AND COMBINATION OF SUCH COLLECTORS

L'invention porte sur un collecteur (1) pour système de traitement de plaie par pression négative, lequel collecteur a une unité de collecte ayant au moins un sac de collecte souple avec une unité perméable au gaz et un absorbeur de liquide (20), et relié à une unité pansement (51) par un ensemble de raccordement d'entrée (30) et à un ensemble capteur (53) par un ensemble de raccordement de détection. Avec le sac de collecte souple, le collecteur (1) occupe un volume moindre. Par l'unité perméable au gaz et l'absorbeur de liquide (20), le liquide et le gaz entrant dans le sac de collecte sont isolés rapidement. De plus, l'unité de collecte peut comprendre de multiples sacs de collecte (10) reliés en série pour former un passage d'écoulement continu, afin de réduire la fréquence de remplacement du collecteur, de telle sorte qu'un temps d'utilisation plus long est obtenu. A collector (1) for a negative pressure wound treatment system has a collector unit having at least a flexible collection bag with a gas permeable unit and a liquid absorber (20), and connected to a dressing unit (51) by an input connection assembly (30) and to a sensor assembly (53) by a detection connection assembly. With the flexible collection bag, the collector (1) occupies less volume. By the gas permeable unit and the liquid absorber (20), the liquid and the gas entering the collection bag are isolated quickly. In addition, the collection unit may include multiple collection bags (10) connected in series to form a continuous flow path, to reduce the frequency of collector replacement, such that an operating time longer is obtained.

Oxide semiconductor field effect transistor and forming method thereof

An oxide semiconductor field effect transistor (OSFET) includes a first insulating layer, a source, a drain, a U-shaped channel layer and a metal gate. The first insulating layer is disposed on a substrate. The source and the drain are disposed in the first insulating layer. The U-shaped channel layer is sandwiched by the source and the drain. The metal gate is disposed on the U-shaped channel layer, wherein the U-shaped channel layer includes at least an oxide semiconductor layer. The present invention also provides a method for forming said oxide semiconductor field effect transistor.

Silicon-containing compound for resistance to hepatitis c virus infection

The present invention provides a silicon-containing compound for resistance to hepatitis c virus infection, and in particular provides a compound represented by formula I, or a pharmaceutically acceptable salt, or a tautomer, or a stereoisomer, or a deuterated compound thereof and mixture among them, a preparation process therefor, and a pharmaceutical composition comprising the same. The present application also provides a use of the compound, or a pharmaceutically acceptable salt, or a tautomer, or a stereoisomer, or a deuterated compound thereof and mixture among them, and a pharmaceutical composition comprising the same in treatment of hepatitis c virus infection.

Improved LED structure

Continuous system of freeze concentration for aqueous solutions

Investigations on the formation and growth behavior of ice crystallization in aqueous solutions reveal an important phenomenon—ice crystal transformation. It leads to very rapid growth of ice crystals and result in grain-shaped and agglomerated large crystals without inside entrainment of solute. This provides a practical basis for a new technology of freeze concentration. The efficient physical process for freeze concentration of aqueous solutions comprises, mainly, refrigerating solutions to a supercooled status without ice nucleation, or without ice formation on the heat transfer surface, instantaneously nucleating the supercooled solution to generate fine ice crystals and make the solution concentrated, producing large, grain/sphere-shaped ice crystals at high rate by growth, transformation and agglomeration of ice crystals under environment of well-controlled endo/exothermal balances. Apparatus for performing the process including, mainly, refrigerating heat exchangers, nucleators, filters and multi-function crystallizers are described. Single-stage and multistage operations can be used for the process and the major steps can be flexibly arranged.

Methods to make piezoelectric ceramic thick film array and single elements and devices

A method of producing at least one piezoelectric element includes depositing a piezoelectric ceramic material onto a surface of a first substrate to form at least one piezoelectric element structure. Then an electrode is deposited on a surface of the at least one piezoelectric element structure. Next, the at least one piezoelectric element structure is bonded to a second substrate, the second substrate being conductive or having a conductive layer. The first substrate is then removed from the at least one piezoelectric element structure and a second side electrode is deposited on a second surface of the at least one piezoelectric element structure. A poling operation is performed to provide the at least one piezoelectric element structure with piezoelectric characteristics. In another embodiment, a material for a thick film element is deposited onto a surface of a first substrate to form a thick film element structure having a thickness of between greater than 10 μm to 100 μm. The at least one thick film element structure is bonded to a second substrate. Thereafter, the first substrate is removed from the at least one thick film element structure using a liftoff process which includes emitting, from a radiation source (such as a laser or other appropriate device), a beam through the first substrate to an attachment interface formed between the first substrate and the at least one thick film element structure at the surface of the first substrate. The first substrate is substantially transparent at the wavelength of the beam, and the beam generates sufficient energy at the interface to break the attachment.

Metallization contact structures and methods for forming multiple-layer electrode structures for silicon solar cells

Metallization contact structures and methods for forming a multiple-layer electrode structure on a solar cell include depositing a conductive contact layer on a semiconductor substrate and depositing a metal bearing ink onto a portion of the conductive contact layer, wherein the exposed portions of the conductive contact layer are adjacent to the metal bearing ink. The conductive contact layer is patterned by removing the exposed portions of the conductive contact layer from the semiconductor substrate. The metal bearing ink is aligned with one or more openings in a dielectric layer of the semiconductor substrate and with unexposed portions of the conductive contact layer. The unexposed portions of the conductive contact layer are interposed between the metal bearing ink and the dielectric layer of the semiconductor substrate such that the conductive contact layer pattern is aligned with metal bearing ink. The semiconductor substrate is thermally processed to form a current carrying metal gridline by sintering the metal bearing ink.

Method and device for integrated protein expression, purification and detection

A method for presenting a target protein or an array of target proteins for analysis is disclosed. The method includes the steps of forming a coding sequence; placing the coding sequence and protein-synthesis components capable of expressing the target protein under selected protein-synthesis conditions in a well on a substrate, the well having a surface which has been functionalized with the second coil-forming peptide; expressing said coding sequence under such conditions, wherein the target protein so synthesized binds to the well through coil-coil heterodimer formation, and is thus presented for analysis in the well in captured form; and washing said well to remove unbound components. The coding sequence includes a first nucleic acid sequence which encodes a first coil-forming peptide having a selected charge and being capable of interacting with a second, oppositely charged coil-forming peptide to form a stable α-helical coiled-coil heterodimer; and a second nucleic acid sequence encoding the target protein. Also disclosed are kits for use in practicing the method.