04-07-2023 дата публикации
Номер: CN116377077A
Принадлежит:
The invention provides a kit and a system for predicting applicability of platinum-containing neoadjuvant therapy to middle and advanced tumor patients, and belongs to the technical field of biological medicine. The invention provides application of a quantitative detection reagent for RNA expression quantity of a molecular marker in tumor tissue to preparation of a kit for predicting applicability of platinum-containing new adjuvant therapy to middle and advanced tumor patients, and is characterized in that the molecular marker comprises one or more of CD24, D9, DUSP23, KRT19, LRRK2, MAL2, PERP, SPINT2, TACSTD2, TSPAN13, C8orf4, FMO5, CAPN8, MDK, SLC20A1, SPINK13, TANC2, CLDN3, RGMB, S100P, MUC4, C19 and f33. According to the gene expression quantity of the molecular marker such as CD24 in the tumor tissue, whether the middle and advanced tumor patients can benefit from platinum-containing neoadjuvant therapy or not is predicted, a judgment basis is provided for personalized tumor therapy ...
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