Hose connection structure of air mattress

A hose connection structure is provided for an air mattress and includes a casing, a plurality of pipe fitting units, a retention board and a resilient buckle. The plurality of pipe fitting units is first jointed together to form an assembly, which is then combined with the retention board and the resilient buckle to then mount inside the casing. The pipe fitting units each comprise a plurality of pipe fittings each having a rear end coupled to an air hose extending to an air mattress. A projection formed on the retention board and a barb formed on the resilient buckle are then put into engagement with a connector of an air pump so as to realize connection of multiple hoses and loosening resistance.

FLUIDIZABLE MEDIUM SUPPORT BED

A fluidizable medium support bed includes a bed body, a blower, a support board, a diffuser board and a metal frame. The bed body includes a support cavity for supporting a fluidizable medium. The bed body includes an expanded polystyrene (EPS) body and a coating covering all outer surfaces of the EPS body. The blower is connected to a bottom surface of the support cavity to provide an airflow. The support board has a plurality of ventholes and is disposed on the bottom surface of the support cavity. The diffuser board is disposed over the support board, wherein the diffuser board is permeable to air but impermeable to the fluidizable medium. The metal frame is disposed over a circumference of the support cavity. 1. A fluidizable medium support bed comprising: an expanded polystyrene (EPS) body; and', 'a coating covering all outer surfaces of the EPS body;, 'a bed body comprising a support cavity for supporting a fluidizable medium, wherein the bed body comprisesa blower connected to a bottom surface of the support cavity to provide an airflow;a support board having a plurality of ventholes and being disposed on the bottom surface of the support cavity;a diffuser board being disposed over the support board, wherein the diffuser board is permeable to air but impermeable to the fluidizable medium; anda metal frame being disposed over a circumference of the support cavity.2. The fluidizable medium support bed of further comprising a spacer disposed under the bed body to raise the bed body.3. The fluidizable medium support bed of claim 1 , wherein the coating is a paint that does not corrode the EPS body.4. The fluidizable medium support bed of claim 1 , wherein the coating has a thickness ranging from about 3 mm to about 6 mm.5. The fluidizable medium support bed of claim 1 , wherein the coating is a waterproof claim 1 , anti-wear paint that does not corrode the EPS body.6. The fluidizable medium support bed of claim 1 , wherein the EPS body has a density ranging from ...

Thermal vacuum therapy and apparatus thereof

An apparatus, for a thermal vacuum therapy by using a suction cup on a skin of a patient, includes a heating unit disposed in the suction cup. The heating unit includes a heat core made of high heat conductive material and a heat retention sleeve made of low heat conductive material, wherein the heat core is wrapped by the heat retention sleeve and is arranged in such a manner that after the heat core rapidly stores heat energy, the heat retention sleeve is adapted for keeping the heat energy at the heat core so as to enable the heat core being gradually released heat within the suction cup during cupping treatment.

Reflective element, backlight module and display device having the same

A reflective element is adapted for use in a backlight module, which includes a plurality of optical lens elements each being provided with a light emitting element. The reflective element includes a plurality of interconnecting reflective portions, each defining a through hole that is adapted for accommodating a corresponding one of the optical lens elements and a corresponding one of the light emitting elements, and being adapted for reflecting light incident from the corresponding one of the light emitting elements. A backlight module and a display device including the reflective element are also disclosed.

Method of Making a Double-Sided Flexible Printed Circuit Type Antenna Device

A method of making a double-sided flexible printed circuit type antenna device includes: aligning first and second alignment units and positioning a substrate on a suction plate; screen printing a conductive paste on a first surface of the substrate to fill first and second holes in the substrate with a conductive paste and to form a first paste pattern; removing and turning the substrate upside down; re-aligning the first and second alignment units and re-positioning the substrate on the suction plate; and screen printing the conductive paste on a second surface of the substrate to further fill the first and second holes with the conductive paste and to form a secondpaste pattern. The first and second paste patterns contact the conductive paste in the first and second holes.

COMMON MODE FILTER

A common mode filter includes a plurality of substrates stacked along an axial direction, a first conductor structure and a second conductor structure disposed on the substrates and including a plurality of first rings and second rings disposed sequentially along the axial direction. The first rings and the second rings are disposed to alternate with each other along the axial direction. The first conductor structure and the second conductor structure are spaced apart by a first clearance in a first direction transverse to the axial direction. 1. A common mode filter , comprising:a plurality of substrates stacked along an axial direction;a first conductor structure disposed on said substrates and including a plurality of first rings connected electrically in series and disposed sequentially along the axial direction; anda second conductor structure disposed on said substrates and including a plurality of second rings connected electrically in series and disposed sequentially along the axial direction;wherein said first rings and said second rings are disposed to alternate with each other along the axial direction; andwherein said first conductor structure and said second conductor structure are spaced apart by a first clearance in a first direction transverse to the axial direction.2. The common mode filter as claimed in claim 1 , wherein:each of said first rings has a first ring section, and a second ring section disposed opposite to said first ring section;each of said second rings has a first ring segment disposed adjacent to said first rings sections of said first rings, and a second ring segment disposed opposite to said first ring segment; andsaid first ring sections of said first rings are spaced apart from said first ring segments of said second rings by the first clearance in the first direction.3. The common mode filter as claimed in claim 2 , wherein said second ring sections of said first rings are spaced apart from said second ring segments of said ...

SYSTEMS, APPARATUSES, AND METHODS OF SUBSTANCE PROCESSING

An apparatus includes a receptacle configured to receive a container containing a substance for processing. The container includes a readable tag having processing information associated with the substance. The apparatus also includes a processing chamber operably coupled to the receptacle and configured to receive the substance and process the substance. The apparatus further includes a controller operably coupled to the processing chamber and configured to generate one or more processing instructions based on the processing information in the readable tag and further based on additional processing information received from a remote device. The processing is also configured to process the substance based on the one or more processing instructions. 1. An apparatus , comprising:a receptacle configured to receive a container containing a substance for processing, the container including a readable tag having processing information associated with the substance;a processing chamber operably coupled to the receptacle and configured to receive the substance and process the substance; anda controller operably coupled to the processing chamber and configured to generate one or more processing instructions based on the processing information in the readable tag and further based on additional processing information received from a remote device, the processing chamber further configured to process the substance based on the one or more processing instructions.2. The apparatus of claim 1 , wherein the receptacle is configured to receive the container containing green coffee beans and the processing chamber includes a roasting chamber configured to roast the green coffee beans.3. The apparatus of claim 2 , wherein the processing chamber is further configured to process about 15 lbs or less of the substance at a given time.4. The apparatus of claim 2 , wherein the processing chamber is further configured to process about 3 lbs or less of the substance at a given time.5. The ...

Human-powered underwater propulsor

A human-powered underwater propulsor for user's moving in water mainly has a power generating module provided within a receiving space inside a waterproof airbag, and the power generating module is coupled to a propulsion unit. The receiving space is formed with an opening end provided with a waterproof ring to be worn by user in such a manner that the receiving space is hermetically sealed to prevent water from entering the receiving space during diving. When user pedals by stepping on two pedals of the power generating module, the power generating module is actuated to cause the flapping of the propulsion unit. Hence, the human-powered underwater propulsor allows user to exercise his feet in the air to reduce drag in diving so that user can moves more easily in the water.

SYSTEMS, APPARATUSES, AND METHODS OF SUBSTANCE PROCESSING

A substance processing system includes a pressurizer configured to pressurize air and a processing chamber configured to process a substance. The system also includes a heat exchanger coupled between the pressurizer and the processing chamber. A nozzle is coupled to the processing chamber such that output from the nozzle comprises a substantially even pressure distribution. 1. An airflow device , comprising:an elongate element defining a lumen, wherein a proximal end of the elongate element is configured to receive pressurized air, and a distal end of the elongate element is configured to output the air with a substantially even pressure distribution.2. The airflow device of claim 1 , wherein the elongate element is configured to accelerate air monotonously through a cross-sectional area of the elongate element.3. The airflow device of claim 1 , wherein the lumen decreases in cross-sectional area from the proximal end to the distal end of the elongate element.4. The airflow device of claim 1 , wherein the elongate element is configured to promote Görtler vortices.5. The airflow device of claim 4 , wherein the Görtler vortices are generated along lateral sides of the distal end.6. The airflow device of claim 1 , wherein the distal end of the elongate element comprises a curve of between about 90° and about 135°.7. The airflow device of claim 1 , wherein the lumen transitions from a circular cross-section to a rectangular cross-section along a length of the elongate element.8. The airflow device of claim 1 , wherein the distal end of the elongate element has a diameter of between about 1 inch and about 3 inches.9. The airflow device of claim 1 , wherein the elongate element is configured to couple between a pressurizer and a processing chamber configured to process a substance.10. A substance processing system claim 1 , comprising:a pressurizer configured to pressurize air;a processing chamber configured to process a substance;a heat exchanger coupled between the ...

Heterocyclic topoisomerase poisons

The invention provides compounds of formula I: wherein R 1 to R 5 have any of the values defined in the specification, as well as pharmaceutically acceptable salts of the compounds, pharmaceutical compositions comprising the compounds, and methods of using the compounds, compositions, or salts to treat cancer. In embodiments, R 4 and R 5 taken together can be a 3, 4, or 5 membered saturated or unsaturated chain comprising members selected from the group consisting of non-peroxide oxygen, sulfur, N(X), and carbon, optionally substituted by oxo; wherein each X is independently absent or is H, O, (C 1 –C 4 )alkyl, phenyl or benzyl; and wherein at least one of the chain members is an N—H group.

Heterocyclic toxins of topoisomerases

Heterocyclic cytotoxic agents

The invention provides compounds of formula (I), wherein R1-R8 ang A-G have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides pharmaceutical compositions comprising a compound of formula (I), processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula (I), and therapeutic methods for treating cancer using compounds of formula (I).

Heterocyclic cytotoxic agents

The invention provides compounds of formula (I) wherein R1-R8 and X and Y have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides pharmaceutical compositions comprising a compound of formula (I), processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula (I), and therapeutic methods for treating cancer using compounds of formula (I).

Turn mattress inherently formed with side guards

A turn mattress includes a plurality of inflatable sacs juxtapositionally connected together within a mattress envelope, each inflatable sac being transverse to a longitudinal axis of the mattress and having a right cell and a left cell separated by a central diaphragm and respectively communicated with an air distributing system to be alternatively inflated or deflated for turning a patient ridden on the mattress from side to side, and a pair of restoring air bags each inherently formed and constantly inflated in each cell, whereby upon deflation of either cell, the restoring air bag as inflated will serve as a side guard for preventing a slipping of the patient away from the mattress laid on a hospital bed.

Coralyne analogues as topoisomerase inhibitors

Det blir fremskaffet protoberbinalkaloidderivater som er nyttige som anticancermidler og fremgangsmåter for anvendelsen av dem. Det blir også fremskaffet protoberberinde- rivater som er nyttige som topoisomeraseinhibitorer. Det blir videre fremskaffet kora- lyn- og nitidinderivater som er topoisomerase I målsøkende terapeutika som er effektive mot kamptotekinresistente cancerceller og er spesielt effektive mot sentralnervesystem- tumorer.

Heterocyclic cytotoxic agents

The invention provides compounds of formula (I) wherein R1-R8 and X and Y have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides pharmaceutical compositions comprising a compound of formula (I), processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula (I), and therapeutic methods for treating cancer using compounds of formula (I).

Heterocyclic topoisomerase poisons

The invention provides compounds of formula I: wherein R<SUB>1 </SUB>to R<SUB>5 </SUB>have any of the values defined in the specification, as well as pharmaceutically acceptable salts of the compounds, pharmaceutical compositions comprising the compounds, and methods of using the compounds, compositions, or salts to treat cancer. In embodiments, R<SUB>4 </SUB>and R<SUB>5 </SUB>taken together can be a 3, 4, or 5 membered saturated or unsaturated chain comprising members selected from the group consisting of non-peroxide oxygen, sulfur, N(X), and carbon, optionally substituted by oxo; wherein each X is independently absent or is H, O, (C<SUB>1</SUB>-C<SUB>4</SUB>)alkyl, phenyl or benzyl; and wherein at least one of the chain members is an N-H group.

Drug discovery method and apparatus

Methods and systems for drug discovery and development are disclosed. Methods and system consistent with the present invention discover drugs. One or more databases comprising chemical and biological interaction data and one or more computer-based data analysis programs may be used to identify compounds that have desired activity at two or more molecular targets that are associated with a disease state for which the drug discovery and development are directed. In addition, one or more databases comprising chemical and biological interaction data and one or more computer-based data analysis programs may be used to identify compounds that (a) have desired activity at one or more molecular targets that are associated with a disease state for which the drug discovery and development are directed and (b) do not have activity or have substantially reduced activity that is undesired at one or more molecular targets that are associated with possible side effects, toxicity, adverse ADME properties, or other properties not intended to be manifested by compounds being developed to treat the disease state associated with the drug discovery.

Heterocyclic topoisomerase poisons

The invention provides a topoisomerase poison of formula (I) wherein R1-R8 have any of the meanings defined in the specification, or a pharmaceutically acceptable salt thereof, as well as pharmaceutical compositions comprising a compound of formula (I) or a salt thereof, intermediates useful for preparing a compound of formula (I), and therapeutic methods comprising administering a compound of formula (I) or a salt thereof.

Coralynanaloge als topoisomerase inhibitoren

Substituted heterocycles as anti-tumor agents

The present invention provides compounds of formula (I): ##STR1## wherein R 1 -R 7 , W, X, Y, and Z have any of the values defined in the specification, and pharmaceutically acceptable salt thereof, that are are useful as anticancer agents. Also disclosed are pharmaceutical compositions comprising one or more compounds of formula I, processes for preparing compounds of formula I, and intermediates useful for preparing compounds of formula I.

Trisbenzimidazoles useful as topoisomerase I inhibitors

The present invention provides anti-neoplastic topoisomerase I inhibitors of the formula: <IMAGE> wherein Ar is (C6-C12)aryl or (6- to 12-membered) heteroaryl comprising 1-3 N, S or non-peroxide O, wherein N is unsubstituted or is substituted with (C1-C4)alkyl; X is H, CN, CHO, OH, acetyl, CF3, OCH3, NO2 or NH2; each Y is individually H, (C1-C4)alkyl or aralkyl; Y' is H or (C1-C4)alkyl; n is 0 or 1; or a pharmaceutically acceptable salt therein.

Substituted heterocycles as anti-tumor agents

The present invention provides compounds of formula (I) wherein R1-R7, W, X, Y, and Z have any of the values defined in the specification, and pharmaceutically acceptable salt thereof, that are useful as anticancer agents. Also disclosed are pharmaceutical compositions comprising one or more compounds of formula (I), processes for preparing compounds of formula (I), and intermediates useful for preparing compounds of formula (I).

Cytotoxic agents

The invention provides compounds of the invention pharmaceutical compositions comprising a compound of the invention, processes for preparing compounds of the invention, intermediates useful for preparing compounds of the invention, and therapeutic methods for treating cancer and other topoisomerase mediated conditions.

Heterocyclic cytotoxic agents

Coralyne analogs as topoisomerase inhibitors

Systems, apparatuses, and methods of substance processing

A substance processing system includes a pressurizer configured to pressurize air and a processing chamber configured to process a substance. The system also includes a heat exchanger coupled between the pressurizer and the processing chamber. A nozzle is coupled to the processing chamber such that output from the nozzle comprises a substantially even pressure distribution.

Pillow cover with neck support

Hospital bed with auto-weighing system

Composto de terbenzimidazol, uso do mesmo, composi;cão farmacêutica, e, processo teapêutico.

"COMPOSTO, USO DO MESMO, COMPOSIçãO FARMACêUTICA, E, PROCESSO TERAPêUTICO". A invenção proporciona um veneno de topoisomerase de fórmula (I) em que Ar é arila ou um grupo heteroaromático contendo nitrogênio, enxofre ou oxigênio; X é H, CN,CHO,OH, acetila, CF~ 3~,O(C~ 1-~C~ 4~) alquila, NO~ 2~, NH~ 2~, halogênio ou halo (C~ 1~-C~ 4~) alquila; cada Y é, individualmente, H, (C~ 1~-C~ 4~) alquila ou aralquila; Y';é fenila, ou metoxifenila; n é 0 ou 1; e cada Z é individualmente, H, (C~ 1~-C~ 4~) alquila, halogênio ou halo (C~ 1~-C~ 4~) alquila; ou um seu sal farmaceuticamente aceitável; para uso na terapia médica (p.ex., o tratamento de infecção fúngica ou câncer). A invenção também proporciona novos compostos de fórmula (I); composições farmacêuticas que compreendem compostos de fórmula (I); e processos terapêuticos que compreendem tratar infecção fúngica ou tratar câncer através da administração de pelo menos um composto de fórmula (I).

Composite hospital bed and method for fabricating the same

Pillow cover with neck support

A pillow cover includes a pillow casing and a neck support. The pillow casing includes a top layer and a bottom layer overlapping therewith, and defining a pillow cavity between the top and bottom layers for receiving a pillow element in the pillow cavity. The neck support is provided at the pillow casing at a position that the neck support is upwardly protruded from the top layer and is supported by the pillow element, wherein the neck support includes a retention pocket provided at the top layer and a neck supporting element received in the retention pocket to upwardly and longitudinally protrude from the top layer for filling at a neck curvature of a user to provide a natural neck support for the user when the head of the user supports on the pillow element.

Heterozyklische cytotoxische wirkstoffe

Tribencimidazoles utiles como inhibidores de topoisomerasa i.

La presente invencion provee inhibidores de topoisomerasa I anti-neoplásticos de la formula (I), en donde Ar es arilo (C2-C12) o heteroarilo (de 5 a 12 miembros) que comprende 1-3 de N, S u O sin peroxido, en donde N está no substituido o substituido con alquilo (C1-C4); X es H, CN, CHO, OH, acetilo, CF3, O-alquilo (C1-C4), NO2, NH2, halogeno o halogeno-alquilo (C1-C4); cada Y es individualmente H. alquilo o aralquilo (C1-C4); Y' es H o alquilo (C1-C4); n es 0 o 1; y cada Z es individualmente H, alquilo (C1-C4), halogeno o halogeno alquilo (C1-C4); o una sal farmacéuticamente aceptable del mismo.

Trisbenzimidazoles useful as topoisomerase I inhibitors

Recombinant antibody, pharmaceutical composition comprising the same, and uses thereof in treating cancers

Disclosed herein are recombinant antibodies or a fragment thereof. According to some embodiments of the present disclosure, each of the recombinant antibodies exhibits a binding affinity to and a neutralizing effect on parathyroid hormone-related protein. Also disclosed herein are pharmaceutical compositions comprising the antibodies or antibody fragments, and uses thereof in treating cancers.

Hospital bed with auto-weighing system

Composite hospital bed and method for fabricating the same

Expandable hospital bed

Topoizomeráz I inhibitor aktivitással rendelkező triszbenzimidazolok, ezeket tartalmazó gyógyászati készítmények és alkalmazásuk

Az (I) általánős képletű vegyületek - a képletben Ar jelentése 6-12 szénatőmős arilcsőpőrt, egy vagy két, 1-4 szénatőmősalkilcsőpőrttal szűbsztitűált, 6-12 szénatőmős arilcsőpőrt, (6-12szénatőmős)aril-(1-4 szénatőmős)alkil-csőpőrt, egy vagy két 1-4szénatőmős alkilcsőpőrttal szűbsztitűált (6-12 szénatőmős)-aril-(1-4szénatőmős)alkil-csőpőrt, vagy 5-12 tagú heterőarilcsőpőrt, amely 1-3nitrőgénatőmőt, kénatőmőt vagy nem perőxidős őxigénatőmőt tartalmaz,és amelyben a nitrőgénatőm szűbsztitűálatlan vagy 1-4 szénatőmősalkilcsőpőrttal, 3-4 szénatőmős ciklőalkilcsőpőrttal vagy ciklőprőpil-metil-csőpőrttal van szűbsztitűálva, és az Ar csőpőrt adőtt esetben abenzőrésszel kőndenzálva van; X jelentése CN, CHO, OH, acetilcsőpőrt, CF3, (1-4 szénatőmős) alkil-őxi-csőpőrt, (3-4 szénatőmős)ciklőalkil-őxi-csőpőrt vagy ciklőprőpil-metőxi-csőpőrt, NO2, NH2, halőgénatőm, halőgén-(1-4 szénatőmős)alkil-csőpőrt, halőgén-(3-4 szénatőmős)ciklőalkil-csőpőrt vagy halőgén-ciklőprőpil-metil-csőpőrt; Y jelentése egymástól függetlenül H, 1-4 szénatőmős alkilcsőpőrt, 3-4szénatőmős ciklőalkilcsőpőrt, ciklőprőpil-metil-csőpőrt vagyaralkilcsőpőrt; Y' jelentése H, 1-4 szénatőmős alkilcsőpőrt, 3-4 szénatőmősciklőalkilcsőpőrt vagy ciklőprőpil-metil-csőpőrt; Z jelentése egymástól függetlenül H, 1-4 szénatőmős alkilcsőpőrt, 3-4szénatőmős ciklőalkilcsőpőrt, ciklőprőpil-metil-csőpőrt, halőgénatőm,halőgén-(1-4 szénatőmős)alkil-csőpőrt, halőgén-(3-4 szénatőmős)ciklőalkil-csőpőrt vagy halőgén-ciklőprőpil-metil-csőpőrt; és n értéke 0 vagy 1 - és gyógyászatilag elfőgadható sóik tőpőizőmeráz Iinhibitőr aktivitásűk következtében főleg daganatellenes szerek ésantifűngális szerek hatóanyagaként alkalmazhatók. ŕ

Plate structure for composite hospital bed and method for fabricating the same

Method of making an inductor

The method for making the inductor includes coiling a enameled wire around a main section of a magnetic core and fixing two wire ends of the enameled wire on two end sections of the magnetic core, the two wire ends of the enameled wire being opposite to each other, the end sections being located at two opposite ends of the main section; putting the magnetic core coiled with the enameled wire into a container, filling the container with a magnetic powder material, and pressing to form semi-finished product having a first end, and a second end that is opposite to the first end; abrading the first and second ends of the semi-finished product until the wire ends are partially exposed; and performing a plating treatment to form two electrodes that are electrically connected to the two wire ends on the first and second ends.

Terbenzimidazoles (inhibitors of topisomerase) useful in medical therapy

Terbenzimidazoles useful for treating fungal infection and cancer (topoisomerase inhibitors)

The specification provides a therapeutic method for the treatment of a fungal infection comprising administering to a mammal afflicted with a fungal infection, particularly a systemic fungal infection, an effective antifungal amount of a compound of general formula (I) wherein: Ar is aryl or a nitrogen-, sulfur- or oxygen-containing heteroaromatic group; X is H, CN, CHO, OH, acetyl, CF3, O(C,-C4)alkyl, NO2, NH2, halogen or halo(C1-C4)alkyl; each Y is individually H, (C,-C4)alkyl or aralkyl; Y' is H, (C1- C4) alkyl, phenyl or methoxyphenyl; each Z is individually H, (C,-C4)alkyl, halogen or halo(C,-C4)alkyl; and n is 0 or 1; or a pharmaceutically acceptable salt thereof. According to one embodiment, Ar is phenyl, and X is Cl or Br, preferably occupying thepara position. As drawn, Z may occupy any position on the benzo moiety. Z is preferably H, halogen, CH3 or CF3. While a number of known inhibitors of human topoisomerase I were found to be ineffective against a fungal topoisomerase I, including nitidine and coralyne, the compounds of formula (I) are inhibitors of fungal topoisomerase I, as demonstrated by their ability to promote DNA cleavage in the presence of Aspergillus topoisomerase I. It was unexpectedly found that the Aspergillus enzyme is completely resistant to some of the most potent human topoisomerase I poisons such as nitidine and coralyne, and to the less potent mono-benzimidazole human topoisomerase I poisons. Furthermore, compounds of formula (I) also are cytotoxic to mammalian tumor cells, including camptothecin-sensitive and camptothecinresistant tumor cells and tumor cell lines exhibiting multi-drug resistance due to expression of the P-glycoprotein. Accordingly, there is provided a therapeutic method for the treatment of cancer comprising administering to a mammal (i.e. a human), an effective anticancer amount of a compound of formula (I), or a pharmaceutically acceptable salt thereof.

Terbenzimidazoles useful for medical therapy (topoisomerase inhibitors)

Battery capacity calculating method and device thereof

Terbencimidazoles utiles para terapia medica(inhibidores de topoisomerasa)

Terbenzimidazoles useful for medical therapy (topoisomerase inhibitors)

自吸式泵浦

【物品用途】;本創作係提供一種可進行液體的汲取和輸送的自吸式泵浦。;【創作特點】;本創作所提供的自吸式泵浦之特徵為：其整體形狀略呈長方體狀，相較於習用之圓柱形設計有明顯之差異，該自吸式泵浦係由一略呈方形之馬達(如左視圖)與一略呈半橢圓狀之泵體(如右視圖)所組成，該泵體之左端係一體成形有一方形連接座，且該馬達在其周面具有數個沿平行方向延伸的肋片，該泵體在其前側與後側亦具有數個沿平行方向設計的線條，以加重本創作之構件概成一直線的流暢感；又於該泵體之右端設有一圓形入水孔，上端設有一圓柱體及一圓拱形體，下端設有一沿該泵體之弧狀所設計的底座，三者間成一平衡之關係位置，給人一種協調與穩重的視覺效果。;本創作之自吸式泵浦與以往圓柱體造型之泵浦相比，本創作具有整體造型簡潔，予人俐落分明的視覺感受，為一種兼具美感與實用的創作。

Systems, apparatuses, and methods of substance processing

A substance processing system includes a pressurizer configured to pressurize air and a processing chamber configured to process a substance. The system also includes a heat exchanger coupled between the pressurizer and the processing chamber. A nozzle is coupled to the processing chamber such that output from the nozzle comprises a substantially even pressure distribution.

Recombinant antibody, pharmaceutical composition comprising the same, and uses thereof in treating cancers

Disclosed herein are recombinant antibodies or a fragment thereof. According to some embodiments of the present disclosure, each of the recombinant antibodies exhibits a binding affinity to and a neutralizing effect on parathyroid hormone-related protein. Also disclosed herein are pharmaceutical compositions comprising the antibodies or antibody fragments, and uses thereof in treating cancers.

Human-powered underwater propulsor

A human-powered underwater propulsor for user's moving in water mainly has a power generating module provided within a receiving space inside a waterproof airbag, and the power generating module is coupled to a propulsion unit. The receiving space is formed with an opening end provided with a waterproof ring to be worn by user in such a manner that the receiving space is hermetically sealed to prevent water from entering the receiving space during diving. When user pedals by stepping on two pedals of the power generating module, the power generating module is actuated to cause the flapping of the propulsion unit. Hence, the human-powered underwater propulsor allows user to exercise his feet in the air to reduce drag in diving so that user can moves more easily in the water.