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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 2. Отображено 2.
07-07-2023 дата публикации

Trachea conformal drag hook, ear rear neck side conformal drag hook and thyroid surgery suite

Номер: CN116392174A
Автор: CHEN XIAOHONG, ZHOU JING, WU JUN, DING YIMING, MA TINGYAO, JING YIXIN, YANG GUANG
Принадлежит:

The invention discloses a trachea conformal drag hook, an ear rear neck side conformal drag hook and a thyroid surgery kit. The conformal retractor for the trachea comprises a first handle, the first hook head is arranged at the far end of the first handle; the first hook head comprises a first clamping arm, a first connecting section, a second clamping arm and an extending section which are sequentially connected end to end, and the first clamping arm and the second clamping arm are perpendicular to the advancing direction of the first handle and used for pushing and pulling an air pipe; the first clamping arm extends from the far end of the first handle in the first direction, the first connecting section extends from the far end of the first clamping arm in the second direction, the second clamping arm extends from the far end of the first connecting section in the direction opposite to the first direction, and the extending section extends from the far end of the second clamping arm ...

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Номер записи: 1
25-04-2023 дата публикации

NOTCH1 intracellular activation domain (NICD1) regulator and application thereof

Номер: CN116004829A
Автор: KONG LU, CHEN XIAOHONG, YANG JIAJIE, ZHOU MENGJIAO, MA TINGYAO, FENG GEXUAN, WANG XUELIAN, LIU HONGLIANG, WEN BINGTING, XU JUAN
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The invention discloses the intracellular transporter CRABP2 of ATRA for the first time, and the intracellular transporter CRABP2 has a new function of preventing an intracellular activation domain (NICD1) of NOTCH1 from entering a cell nucleus. Experimental results show that in a 83 cell line with relatively low invasiveness, after the expression of CRABP2 is inhibited, the number of NICD1 entering a cell nucleus is obviously increased. On the contrary, when the NICD1 activation inhibitor DAPT is used for treating the cells, the up-regulation of the CRABP2 is also seen, which indicates that a mutual antagonism regulation mechanism exists between the CRABP2 and the NICD1, and is also the embodiment of the new function of the CRABP2. This phenomenon does not exist in an LM cell line having lung metastasis ability. The retinoic acid system is indirectly prompted to have dysfunction in metastatic ACC cells, so that the retinoic acid system can be used as a syndrome of response capability when ...

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Номер записи: 2