Настройки

Укажите год
-

Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

Подробнее
-

Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

Подробнее

Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
Ведите корректный номера.
Ведите корректный номера.
Ведите корректный номера.
Ведите корректный номера.
Укажите год
Укажите год
Применить Всего найдено 4. Отображено 4.
29-09-2011 дата публикации

NEW INDOLE DERIVATIVE AND DRUG USE THEREOF

Номер: JP2011190206A
Автор: TAJIMA YASUMITSU, YAMASHITA ATSUYUKI, KONDO YURIE, CHIKAMATSU KAORI, HIRAMATSU NAOKI, MAKINO MICHIHIRO, KITAMOTO KATSUNORI, KATAOKA DAISUKE, NAGAI KAZUSHIGE, GOTO IZUMI, TORII MASASHI, SUZUKI KIMIE, IWAI HISAKAZU, HIROOKA HIROKO
Принадлежит:

PROBLEM TO BE SOLVED: To provide a compound having a glucokinase activating action. SOLUTION: The compound is represented by formula (I) [wherein connecting group (1) is a single bond or a double bond; connecting group (2) is N-C=C or C=C-N; and ring A is a thiazolyl group, pyridyl group, a benzothiazolyl group or the like] and a prodrug thereof is described. COPYRIGHT: (C)2011,JPO&INPIT ...

Подробнее
Номер записи: 1
25-02-2010 дата публикации

GLP-1 DERIVATIVE AND USE THEREOF

Номер: JP2010043001A
Автор: SHIROMORI TAKAHITO, HAYASHI YUJI, MAKINO MICHIHIRO
Принадлежит:

PROBLEM TO BE SOLVED: To provide a new GLP-1 derivative having a greatly improved capability of being absorbed through a mucous membrane. SOLUTION: There is disclosed a peptide that has (Lys)n-Arg (wherein n is an integer of 4 to 8, and Arg is in the form of a carboxylic acid) added to the C terminus of a peptide comprising an amino acid sequence corresponding to GLP-1 (7-35) or GLP-1 (7-36) or an amino acid sequence having the deletion, substitution and/or addition of one or several amino acid residues in the above amino acid sequence and having GLP-1 activity. The amino acid residue at the 8-position in the amino acid sequence of GLP-1 is preferably serine or glycine, and n is preferably 5. COPYRIGHT: (C)2010,JPO&INPIT ...

Подробнее
Номер записи: 2
13-01-2011 дата публикации

NEW THIOPHENE CARBOXAMIDE DERIVATIVE AND MEDICAL USE THEREOF

Номер: JP2011006366A
Автор: YAMASHITA ATSUYUKI, CHIKAMATSU KAORI, TAKAHASHI NAOKI, IWAI HISAKAZU, OGAMI MASAKAZU, SAKAIRI MASAO, WATANABE NOBUHIDE, FUJIEDA HIROKI, KATAOKA DAISUKE, MAKINO MICHIHIRO, KATO NORIYASU, MIYAZAWA TOSHIYUKI, NAGAI KAZUSHIGE, KASUGAI NORIYASU, KATAOKA HIROYO, HIRAMATSU NAOKI, TSURUTA NOBUAKI, KONDO YURIE, MIYOSHI MIKA, MURAKAMI SEI, GOTO IZUMI, IDO TORU, SUZUKI KIMIE, HARADA SATOKO, LANG MARTIN, SEIFERT HANS-JUERGEN MARKUS, WOLF KAARINA KRISTINA
Принадлежит:

PROBLEM TO BE SOLVED: To provide a compound having glucokinase activating action. SOLUTION: A medical composition containing a compound expressed by general formula (I) (wherein X denotes a nitrogen atom or CR6, R6 denotes a hydrogen atom; R1 denotes a hydrogen atom, a 1-6C alkyl group, a 1-6C alkoxy group or a 1-6C alkylthio group, R2 denotes a hydrogen atom or a fluorine atom; R3 denotes a hydrogen atom or a 1-6C alkyl group; and one of R4 and R5 denotes a hydrogen atom or a 1-6C alkyl group, and another thereof denotes a 1-6C alkylene carboxylic acid, a 1-6C alkylsulfonyl group, 1-6C alkylcarbonyl group or CONH2), a prodrug or a pharmacologically permitted salt as an active ingredient is provided. COPYRIGHT: (C)2011,JPO&INPIT ...

Подробнее
Номер записи: 3
12-01-2012 дата публикации

NEW THIOPHENECARBOXAMIDE DERIVATIVE AND MEDICINAL USE THEREOF

Номер: JP2012006899A
Автор: YAMASHITA ATSUYUKI, CHIKAMATSU KAORI, TAKAHASHI NAOKI, IWAI HISAKAZU, OGAMI MASAKAZU, SAKAIRI MASAO, WATANABE NOBUHIDE, FUJIEDA HIROKI, KATAOKA DAISUKE, MAKINO MICHIHIRO, KATO NORIYASU, MIYAZAWA TOSHIYUKI, NAGAI KAZUSHIGE, KASUGAI NORIYASU, KATAOKA HIROYO, HIRAMATSU NAOKI, TSURUTA NOBUAKI, KONDO YURIE, MIYOSHI MIKA, MURAKAMI SEI, GOTO IZUMI, IDO TORU, SUZUKI KIMIE, HARADA SATOKO, LANG MARTIN, SEIFERT HANS-JUERGEN MARKUS, WOLF KAARINA KRISTINA
Принадлежит:

PROBLEM TO BE SOLVED: To provide a compound having glucokinase activation action. SOLUTION: The compound is represented by general formula (I) [wherein X is a nitrogen atom or CR6; R6 is a hydrogen atom or halogen atom; R1 is a hydrogen atom, 1C-6C alkyl, 1C-6C alkoxy or 1C-6C alkylthio; R2 is a hydrogen atom or fluorine atom; R3 is a hydrogen atom or 1C-6C alkyl; one of R4 and R5 is a hydrogen atom or 1C-6C alkyl and the other is a 1C-6C alkylenecarboxylic acid, 1C-6C alkylsulfonyl, 1C-6C alkylcarbonyl or CONH2]. COPYRIGHT: (C)2012,JPO&INPIT ...

Подробнее
Номер записи: 4