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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 23. Отображено 23.
30-06-2004 дата публикации

Methods for modulating ikkalpha activity

Номер: AU2003297700A8
Автор: MARCU KENNETH, LI XIANG, YANG JIANFEI, LI JUN, KENNETH MARCU, XIANG LI, JIANFEI YANG, JUN LI
Принадлежит:

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Номер записи: 1
29-01-2009 дата публикации

Pharmaceutical composition and pharmaceutical kit for the treatment of hepatocellular carcinoma

Номер: AU2007356840A1
Автор: BOLONDI LUIGI, GIOVANNINI CATIA, MARCU KENNETH, CHIECO PASQUALE, LUIGI BOLONDI, CATIA GIOVANNINI, KENNETH MARCU, PASQUALE CHIECO
Принадлежит:

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Номер записи: 2
18-07-2013 дата публикации

Pharmaceutical composition and pharmaceutical kit for the treatment of hepatocellular carcinoma

Номер: AU2007356840B2
Автор: CHIECO PASQUALE, BOLONDI LUIGI, MARCU KENNETH, GIOVANNINI CATIA, CHIECO, PASQUALE, BOLONDI, LUIGI, MARCU, KENNETH, GIOVANNINI, CATIA
Принадлежит: Universita di Bologna

The present invention provides pharmaceutical compositions for the treatment of hepatocellular carcinoma (HCC) comprising Notch3 inhibitors and a chemotherapeutic agent, methods for the preparation of said compositions and a medical treatment comprising the administration of said pharmaceutical compositions in patients in need thereof.

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Номер записи: 3
29-08-2017 дата публикации

PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL KIT FOR THE TREATMENT OF HEPATOCELLULAR CARCINOMA

Номер: CA0002694267C
Автор: CHIECO, PASQUALE, MARCU, KENNETH, GIOVANNINI, CATIA, BOLONDI, LUIGI, BOLONDI LUIGI, GIOVANNINI CATIA, CHIECO PASQUALE, MARCU KENNETH
Принадлежит: ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA, ALMA MATER STUDIORUM - UNIV DI BOLOGNA

The present invention provides pharmaceutical compositions for the treatment of hepatocellular carcinoma (HCC) comprising Notch3 inhibitors and a chemotherapeutic agent, methods for the preparation of said compositions and a medical treatment comprising the administration of said pharmaceutical compositions in patients in need thereof.

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Номер записи: 4
30-06-2004 дата публикации

METHODS FOR MODULATING IKKAlpha ACTIVITY

Номер: AU2003297700A1
Автор: LI JUN, LI XIANG, YANG JIANFEI, MARCU KENNETH, JUN LI, XIANG LI, JIANFEI YANG, KENNETH MARCU
Принадлежит:

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Номер записи: 5
29-01-2009 дата публикации

PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL KIT FOR THE TREATMENT OF HEPATOCELLULAR CARCINOMA

Номер: CA0002694267A1
Автор: MARCU, KENNETH, GIOVANNINI, CATIA, CHIECO, PASQUALE, BOLONDI, LUIGI, BOLONDI LUIGI, GIOVANNINI CATIA, CHIECO PASQUALE, MARCU KENNETH
Принадлежит: Alma Mater Studiorum - Università di Bologna, Catia Giovannini, Kenneth Marcu, Luigi Bolondi, Pasquale Chieco

The present invention provides pharmaceutical compositions for the treatment of hepatocellular carcinoma (HCC) comprising Notch3 inhibitors and a chemotherapeutic agent, methods for the preparation of said compositions and a medical treatment comprising the administration of said pharmaceutical compositions in patients in need thereof.

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Номер записи: 6
12-12-2003 дата публикации

Methods for the identification of ikkalpha function and other genes useful for treatment of inflammatory diseases

Номер: AU2003249645A8
Автор: MARCU KENNETH, LI XIANG, PEET GREGORY, LI JUN, HANIDU ADEDAYO, MISCHE SHEENAN, KENNETH MARCU, XIANG LI, GREGORY PEET, JUN LI, ADEDAYO HANIDU, SHEENAN MISCHE
Принадлежит:

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Номер записи: 7
12-12-2003 дата публикации

METHODS FOR THE IDENTIFICATION OF IKKAlpha FUNCTION AND OTHER GENES USEFUL FOR TREATMENT OF INFLAMMATORY DISEASES

Номер: AU2003249645A1
Автор: MARCU KENNETH, HANIDU ADEDAYO, LI XIANG, PEET GREGORY, MISCHE SHEENAN, LI JUN, KENNETH MARCU, ADEDAYO HANIDU, XIANG LI, GREGORY PEET, SHEENAN MISCHE, JUN LI
Принадлежит:

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Номер записи: 8
18-08-2010 дата публикации

Pharmaceutical composition and pharmaceutical kit for the treatment of hepatocellular carcinoma

Номер: CN0101808648A
Автор: LUIGI BOLONDI, CATIA GIOVANNINI, PASQUALE CHIECO, KENNETH MARCU, BOLONDI LUIGI, GIOVANNINI CATIA, CHIECO PASQUALE, MARCU KENNETH
Принадлежит:

The present invention provides pharmaceutical compositions for the treatment of hepatocellular carcinoma (HCC) comprising Notch3 inhibitors and a chemotherapeutic agent, methods for the preparation of said compositions and a medical treatment comprising the administration of said pharmaceutical compositions in patients in need thereof.

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Номер записи: 9
23-07-2009 дата публикации

METHODS FOR THE IDENTIFICATION OF IKKALFA FUNCTION AND OTHER GENES USEFUL FOR TREATMENT OF INFLAMMATORY DISEASES

Номер: US2009186010A1
Автор: LI JUN, HANIDU ADEDAYO, LI XIANG, PEET GREGORY WHITTEN, MISCHE SHEENAH, MARCU KENNETH
Принадлежит:

The invention provides a method for identifying genes involved in the NF-kappaB pathway comprised of the steps of determining the level of expression of a gene in an experimental sample obtained from the cells having deficient levels of a component of the NF-kappaB pathway; determining the level of expression of said gene in a control sample obtained from wild type cells having levels of a component of a biological pathway; selecting genes having a level of expression that are modulated in said experimental sample relative to said wild type sample. The invention also provides a method of treating inflammatory related diseases by modulating the activity of IKKalpha.

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Номер записи: 10
16-08-2007 дата публикации

Methods for Modulating IKKalpha Activity

Номер: US2007191300A1
Автор: LI JUN, LI XIANG, YANG JIANFEI, MARCU KENNETH
Принадлежит:

A method for modulating NF-kappaB dependent gene transcription in a cell comprised of modulating IKKalpha protein activity in the cell. The present invention also provides siRNA compositions and methods thereof for modulating NF-kappaB dependent gene transcription.

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Номер записи: 11
07-06-2007 дата публикации

Methods for the Identification of IKKalpha Function and other Genes Useful for Treatment of Inflammatory Diseases

Номер: US2007128648A1
Автор: LI JUN, HANIDU ADEDEYO, LI XIANG, PEET GREGORY W, MISCHE SHEENAH, MARCU KENNETH, PEET GREGORY W.
Принадлежит:

The invention provides a method for identifying genes involved in the NF-kappaB pathway comprised of the steps of determining the level of expression of a gene in an experimental sample obtained from the cells having deficient levels of a component of the NF-kappaB pathway; determining the level of expression of said gene in a control sample obtained from wild type cells having levels of a component of a biological pathway; selecting genes having a level of expression that are modulated in said experimental sample relative to said wild type sample. The invention also provides a method of treating inflammatory related diseases by modulating the activity of IKKalpha.

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Номер записи: 12
16-05-2017 дата публикации

Pharmaceutical composition and pharmaceutical kit for the treatment of hepatocellular carcinoma

Номер: US0009649379B2
Автор: Luigi Bolondi, Catia Giovannini, Pásquale Chieco, Kenneth Marcu, BOLONDI LUIGI, GIOVANNINI CATIA, CHIECO PÁSQUALE, MARCU KENNETH, Bolondi Luigi, Giovannini Catia, Chieco Pásquale, Marcu Kenneth
Принадлежит: ALMA MATER STUDIORUM—UNIVERSITA' DI BOLOGNA, BOLONDI LUIGI, GIOVANNINI CATIA, CHIECO PÁSQUALE, MARCU KENNETH, Bolondi Luigi, Giovannini Catia, Chieco Pásquale, Marcu Kenneth

The present invention provides pharmaceutical compositions for the treatment of hepatocellular carcinoma (HCC) comprising Notch3 inhibitors and a chemotherapeutic agent, methods for the preparation of said compositions and a medical treatment comprising the administration of said pharmaceutical compositions in patients in need thereof.

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Номер записи: 13
29-07-2010 дата публикации

PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL KIT FOR THE TREATMENT OF HEPATOCELLULAR CARCINOMA

Номер: US20100189775A1
Автор: Luigi Bolondi, Catia Giovannini, Pasquale Chieco, Kenneth Marcu, BOLONDI LUIGI, GIOVANNINI CATIA, CHIECO PASQUALE, MARCU KENNETH
Принадлежит:

The present invention provides pharmaceutical compositions for the treatment of hepatocellular carcinoma (HCC) comprising Notch3 inhibitors and a chemotherapeutic agent, methods for the preparation of said compositions and a medical treatment comprising the administration of said pharmaceutical compositions in patients in need thereof.

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Номер записи: 14
23-11-2010 дата публикации

Methods for modulating IKK activity

Номер: US0007838268B2
Автор: Jun Li, Xiang Li, Jianfei Yang, Kenneth Marcu, LI JUN, LI XIANG, YANG JIANFEI, MARCU KENNETH
Принадлежит: Boehringer Ingelheim International GmbH, BOEHRINGER INGELHEIM INT, BOEHRINGER INGELHEIM INTERNATIONAL GMBH

A method for modulating NF-B dependent gene transcription in a cell comprised of modulating IKK protein activity in the cell. The present invention also provides siRNA compositions and methods thereof for modulating NF-B dependent gene transcription.

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Номер записи: 15
24-06-2004 дата публикации

METHODS FOR MODULATING IKKα ACTIVITY

Номер: WO2004053078A2
Автор: Jianfei Yang, Jun Li, Kenneth Marcu, Xiang Li
Принадлежит: BOEHRINGER INGELHEIM PHARMACEUTICALS, INC.

A method for modulating NF-κB dependent gene transcription in a cell comprised of modulating IKKα protein activity in the cell. The present invention also provides siRNA compositions and methods thereof for modulating NF-κB dependent gene transcription.

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Номер записи: 16
12-10-2004 дата публикации

Biologically active alternative form of the IKKα IκB kinase

Номер: US6803204B2
Автор: Kenneth B. Marcu, Margery A. Connelly
Принадлежит: Research Foundation of State University of New York

The present invention provides isolated IκB kinases that regulate NFκB gene transcription that lack both a leucine zipper like α-helix domain and helix-loop-helix domain. Also provided are the amino acid sequences of these kinases and the nucleotide sequence encoding these kinases, and other related protein and nucleic acid molecules.

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Номер записи: 17
22-01-2004 дата публикации

Methods for the identification of IKKalpha function and other genes useful for treatment of imflammatory diseases

Номер: US20040014111A1
Автор: Adedayo Hanidu, Gregory Peet, Jun Li, Kenneth Marcu, Sheenah Mische, Xiang Li
Принадлежит: Boehringer Ingelheim Pharmaceuticals Inc

The invention provides a method for identifying genes involved in the NF-κB pathway comprised of the steps of determining the level of expression of a gene in an experimental sample obtained from the cells having deficient levels of a component of the NF-κB pathway; determining the level of expression of said gene in a control sample obtained from wild type cells having levels of a component of a biological pathway; selecting genes having a level of expression that are modulated in said experimental sample relative to said wild type sample. The invention also provides a method of treating inflammatory related diseases by modulating the activity of IKKα.

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Номер записи: 18
23-05-2000 дата публикации

Y2H56 A strong IKK binding protein

Номер: US6066474A
Автор: Kenneth B. Marcu
Принадлежит: Research Foundation of State University of New York

The present invention provides an isolated IκB kinase binding protein designated Y2H56 and functional equivalents therof. The amino acid sequence of Y2H56, the nucleotide sequence encoding Y2H56, and other related protein and nucleic acid molecules are also provided.

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Номер записи: 19
04-12-2003 дата публикации

Methods for the identification of ikkalpha function and other genes useful for treatment of inflammatory diseases

Номер: CA2485184A1
Автор: Adedayo Hanidu, Gregory Peet, Jun Li, Kenneth Marcu, Sheenah Mische, Xiang Li
Принадлежит: Individual

The invention provides a method for identifying genes involved in the NF-.kappa.B pathway comprised of the steps of determining the level of expression of a gene in an experimental sample obtained from the cells having deficient levels of a component of the NF-.kappa.B pathway; determining the level of expression of said gene in a control sample obtained from wild type cells having levels of a component of a biological pathway; selecting genes having a level of expression that are modulated in said experimental sample relative to said wild type sample. The invention also provides a method of treating inflammatory related diseases by modulating the activity of IKK.alpha..

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Номер записи: 20
12-05-2011 дата публикации

Methods for modulating ikkalpha activity

Номер: US20110112284A1
Автор: Jianfei Yang, Jun Li, Kenneth Marcu, Xiang Li
Принадлежит: BOEHRINGER INGELHEIM INTERNATIONAL GMBH

A method for modulating NF-κB dependent gene transcription in a cell comprised of modulating IKKα protein activity in the cell. The present invention also provides siRNA compositions and methods thereof for modulating NF-κB dependent gene transcription.

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Номер записи: 21
16-08-2007 дата публикации

Methods for Modulating IKKalpha Activity

Номер: US20070191300A1
Автор: Jianfei Yang, Jun Li, Kenneth Marcu, Xiang Li
Принадлежит: Individual

A method for modulating NF-κB dependent gene transcription in a cell comprised of modulating IKKα protein activity in the cell. The present invention also provides siRNA compositions and methods thereof for modulating NF-κB dependent gene transcription.

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Номер записи: 22
04-12-2003 дата публикации

METHODS FOR THE IDENTIFICATION OF IKKα FUNCTION AND OTHER GENES USEFUL FOR TREATMENT OF INFLAMMATORY DISEASES

Номер: WO2003099781A2
Автор: Adedayo Hanidu, Gregory Peet, Jun Li, Kenneth Marcu, Sheenan Mische, Xiang Li
Принадлежит: BOEHRINGER INGELHEIM PHARMACEUTICALS, INC.

The invention provides a method for identifying genes involved in the NF-κB pathway comprised of the steps of determining the level of expression of a gene in an experimental sample obtained from the cells having deficient levels of a component of the NF-κB pathway; determining the level of expression of said gene in a control sample obtained from wild type cells having levels of a component of a biological pathway; selecting genes having a level of expression that are modulated in said experimental sample relative to said wild type sample. The invention also provides a method of treating inflammatory related diseases by modulating the activity of IKKα.

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Номер записи: 23