Faser-Wickelvorrichtung.

Amidomethyl-substituierte 2-(4-Sulfonilamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-ylderivate, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

FUNGICIDES CONNECTIONS

FUNGICIDES

AMINOALKYLAMIDOMETHYLSUBSTITUIERTE 2 (4SULFONYLAMINO) - 3-HYDROXY-3,4-DIHYDRO-2H-CROMEN - YL of DERIVATIVES AND YOUR USE AS POTASSIUM CHANNEL BLOCKERS

AMIDOMETHYL SUBSTITUTING 2 (4-SULFONILAMINO) - 3 - HIDROXY-3,4-DIHYDRO 2H-CHROMEN-6-YL-DERIVATE, PROCEDURES AND INTERMEDIATE PRODUCTS FOR YOUR PRODUCTION AND THESE CONNECTIONS CONTAINING DRUGS

FUNGICIDES

Fungicides

The invention relates to compounds of general formula I, where A<1>, R<1>, R<2 >and Y are as defined in the description; and to their use as phytopathogenic fungicides.

Amidomethyl-substituted 2-(4-sulfonilamino)-3-hidroxy-3,4-dihydro-2H-chromium-6-yl-derivatives and drugs containing said compounds

AMINOALKYLAMIDOMETHYLSUBSTITUIERTE 2-(4-SULFONYLAMINO)-3-HYDROXY-3,4-DIHYDRO-2H-CROMEN-6-YL DERIVATE UND IHRE VERWENDUNG ALS KALIUMKANALBLOCKER

Aminoalkyl-amidomethyl-substituted 2- (4-sulphonylamino) -3-hydroxy-3 , 4-dihydro-2H-cromen-6-yl derivatives and their use as potassium channel blockers

FILAMENT WINDING SYSTEM

A delivery head assembly for a filament winding device, having an input end for fibrous tows and an output end for applying superimposed layers of the tows in a helical pattern onto a mandrel to produce a generally tubular article having varying contours, in which the delivery head is one of two delivery head assemblies, one comprising an upper distributing, feeding, and cutting assembly and a structurally similar lower distributing, feeding, and cutting assembly disposed in inverted relationship to and at a vertical angle to the upper assembly, the two assemblies being juxtaposed at their output ends and spaced apart from each other at their input ends, and each assembly includes a separate set of rollers for adding the cut tow back into the winding band when that tow is again to be applied to the mandrel, is disclosed.

Amidomethyl-substituted 2-(4-sulfonilamino)-3-hidroxy-3,4-dihydro-2H-chromium-6-yl-derivatives and drugs containing said compounds

Fungicides

Compounds of formula (I) or (II):or salts therefor are used as phytopathogenic fungicides wherein the various radicals and substitutents are as defined in the description. Pesticidal compositions contain these compounds together with an agriculturally acceptable diluent or carrier. The compounds and compositions are applied in methods for combating pests.

AMIDOMETHYL-SUBSTITUTED 2-(4-SULFONILAMINO)-3-HIDROXY-3,4-DIHYDRO-

The invention relates to compounds of general formula (I), wherein the meaning of R1, R2, R3, R4, R5and R6 is given in a description, to a method for producing said compounds and to intermediate products thereof. Drugs containing the inventive compounds of formula (1) are also disclosed. © KIPO & WIPO 2007 ...

Faser-Wickelvorrichtung.

Amidomethyl-substituted 2-(4-sulphonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl derivatives, process and intermediate products for their preparation and medicaments containing these compounds

Fungicides

AMIDOMETHYL-SUBSTITUTED 2-(4-SULFONILAMINO)-3-HIDROXY-3,4-DIHYDRO-2H-CHROMIUM-6-YL-DERIVATIVES AND DRUGS CONTAINING SAID COMPOUNDS

AMIDOMETHYL-SUBSTITUIERTE 2-(4-SULFONILAMINO)-3-HIDROXY-3,4-DIHYDRO- 2H-CHROMEN-6-YL-DERIVATE, VERFAHREN UND ZWISCHENPRODUKTE ZU IHRER HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL

Amidomethyl-substituierte 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2h-chromen-6-ylderivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Es werden Verbindungen der allgemeinen Formel I, , worin, R1, R2, R3, R4, R5 und R6 die in der Beschreibung angegebenen Bedeutungen besitzen sowie ein Verfahren zur Herstellung dieser Verbindungen und Zwischenprodukte dieses Verfahrens beschrieben. Ferner werden die Verbindungen der Formel I enthaltende Arzneimittel angegeben.

Use of Amidomethyl-Substituted 2-(4-Sulfonylamino)-3-Hydroxy-3,4-Dihydro-2H-Chromen-6-yl-Compounds in the Treatment of Cardiac Arrhythmia and Other Disease States

The use of compounds corresponding to formula I: in which R¹, R², R³, R⁴, R⁵ and R⁶ have the meanings given in the description for treating cardiac arrhythmias and other disease states.

AMINOALKYL-AMIDOMETHYL-SUBSTITUTED 2-(4-SULPHONYLAMINO)-3-HYDROXY-3, 4-DIHYDRO-2H-CROMEN-6-YL DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL BLOCKERS

Cardiovascular active compounds of the general formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and n have the meanings given in the description, and also a process for the preparation of these compounds and intermediate products of this process are described. Furthermore, pharmaceutical compositions comprising the compounds of Formula (I) are specified. © KIPO & WIPO 2008 ...

FUNGIZIDE

FUNGIZIDE

Amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl compounds, a process and intermediates for their production, and pharmaceutical compositions containing them

Compounds corresponding to formula I: in which R 1 , R 2 , R 3 , R 4 , R 5 and R 6 have the meanings given in the description; a process for the preparation of these compounds; intermediate products used to prepare such compounds, and pharmaceutical compositions containing such compounds.

Amidomethyl-substituierte 2-(4-Sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-ylderivade, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Es werden Verbindungen der allgemeinen Formel I, DOLLAR F1 worin R·1·, R·2·, R·3·, R·4·, R·5· und R·6· die in der Beschreibung angegebenen Bedeutungen besitzen, sowie ein Verfahren zur Herstellung dieser Verbindungen und Zwischenprodukte dieses Verfahrens beschrieben. Ferner werden die Verbindungen der Formel I enthaltende Arzneimittel angegeben.

FUNGIZIDE VERBINDUNGEN

FUNGIZIDE VERBINDUNGEN

FUNGICIDES

Use of compounds of general formula (I) or (II) or salts thereof as phytopathogenic fungicides wherein the various radicals and substituents are as defined in the description, pesticidal compositions containing them and method for combating pests which comprises applying these. © KIPO & WIPO 2007 ...

FUNGICIDES

The invention relates to compounds of general formula I, where A1, R1, R2 and Y are as defined in the description; and to their use as phytopathogenic fungicides. © KIPO & WIPO 2007 ...

Amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl compounds, a process and intermediates for their production, and pharmaceutical compositions containing them

Compounds corresponding to formula I: in which R¹, R², R³, R⁴, R⁵ and R⁶ have the meanings given in the description; a process for the preparation of these compounds; intermediate products used to prepare such compounds, and pharmaceutical compositions containing such compounds.

Aminoalkyl-amidomethyl-substituted 2-(4-sulphonylamino)-3-hydroxy-3,4-dihydro-2H-chroman-6-yl derivatives

Compounds corresponding to formula I, wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 and n have the meanings given in the description, and also a process for the preparation of these compounds and intermediate products of this process. Furthermore, pharmaceutical compositions comprising the compounds of Formula I and related methods of treatment.

DERIVATIVES OF 2 (4-SULFONILAMINO) -3-HIDROXI-3,4-DIHIDRO-2H-CROMEN-6-ILOSUSTITUIDOS WITH AMIDOMETILO PROCEDURE AND INTERMEDIATE PRODUCTS FOR ITS PREPARATION AND MEDECINES THAT CONTAIN TO THESE COMPOUNDS

Reivindicación 1: Compuesto de la fórmula general (1), en donde: R1 significa alquilo C1-4; R2 significa alquilo C1-4; R3 significa fenilo, que está eventualmente sustituido, 1-2 veces, con halógeno, alquilo C1-4, alcoxi C1-4 o trifluorometilo; naftilo o bifenilo; R4 significa hidrógeno; alquilo C1-6 o cicloalquil(C3-7)alquilo(C1-4); R5 significa hidrógeno; y R6 significa alquilo C1-6; fenil-alquilo(C1-4), cuyo grupo fenilo está eventualmente sustituido 1 vez con halógeno; furil-alquilo(C1- 4) o tetrahidronaftilo; o R5 y R6, junto con el nitrógeno al que están unidos, forman un anillo de piperazina sin sustituir el cual está eventualmente sustituido con fenilo.

Aminoalkyl-amidomethyl-substituted 2- (4-sulphonylamino) -3-hydroxy-3 , 4-dihydro-2h-cromen-6-yl derivatives and their use as potassium channel blockers

Use of amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl-compounds in the treatment of cardiac arrhythmia and other disease states

The use of compounds corresponding to formula I: in which R1, R2, R3, R4, R5 and R6 have the meanings given in the description for treating cardiac arrhythmias and other disease states.

Aminoalkyl-Amidomethyl-Substituted 2-(4-Sulphonylamino)- 3-Hydroxy-3,4-Dihydro-2H-Chroman-6-yl Derivatives

Compounds corresponding to formula I, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and n have the meanings given in the description, and also a process for the preparation of these compounds and intermediate products of this process. Furthermore, pharmaceutical compositions comprising the compounds of Formula I and related methods of treatment.

Fungicides

The invention relates to compounds of general formula I, where A<1>, R<1>, R<2 >and Y are as defined in the description; and to their use as phytopathogenic fungicides.

Aminoalkyl-amidomethyl-substituted 2- (4-sulphonylamino) -3-hydroxy-3 , 4-dihydro-2h-cromen-6-yl derivatives and their use as potassium channel blockers

The invention describes cardiovascular active compounds of the general formula (I), wherein R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7>, R<8>, R<9>, R<10> and n have the meanings given in the description, and also a process for the preparation of these compounds and intermediate products of this process are described. Furthermore, pharmaceutical compositions comprising the compounds of Formula (I) are specified.

Aminoalkyl-amidomethyl-substituted 2-(4-sulphonylamino)-3-hydroxy-3,4-dihydro-2H-chroman-6-yl derivatives

Compounds corresponding to formula I, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and n have the meanings given in the description, and also a process for the preparation of these compounds and intermediate products of this process. Furthermore, pharmaceutical compositions comprising the compounds of Formula I and related methods of treatment.

Amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2h-chromen-6-yl compounds, a process and intermediates for their production, and pharmaceutical containing the compound

Fungicides

2-pyridylmethylamine derivatives useful as fungicides

2-pyridylmethylamine derivatives useful as fungicides

Compounds of formula (I) and salts thereof as phytopathogenic fungicides wherein A1 is substituted 2-pyridyl; A2 is optionally substituted phenyl; L is -(C=O)-, -SO2- or -(C=S)-; R1 is hydrogen, optionally substituted alkyl or acyl; and R2 is hydrogen or optionally substituted alkyl are useful phytopathogenic fungicides.

Filament winding system

A delivery head assembly for a filament winding device, having an input end for fibrous tows and an output end for applying superimposed layers of the tows in a helical pattern onto a mandrel to produce a generally tubular article having varying contours, in which the delivery head is one of two delivery head assemblies, one comprising an upper distributing, feeding, and cutting assembly and a structurally similar lower distributing, feeding, and cutting assembly disposed in inverted relationship to and at a vertical angle to the upper assembly, the two assemblies being juxtaposed at their output ends and spaced apart from each other at their input ends, and each assembly includes a separate set of rollers for adding the cut tow back into the winding band when that tow is again to be applied to the mandrel, is disclosed.

Amidomethyl-substituted 2-(4-sulfonilamino)-3-hidroxy-3,4-dihydro-2h-chromen-6-yl-derivatives, process and drugs containing these compounds

The invention relates to compounds of general formula (I), wherein the meaning of R1, R2, R3, R4, R5 and R6 is given in a description, to a method for producing said compounds and to intermediate products thereof. Drugs containing the inventive compounds of formula (1) are also disclosed.

2-pyridylmethylamine derivatives useful as fungicides

Compounds of formula (I) and salts thereof as phytopathogenic fungicides wherein A1 is substituted 2-pyridyl; A2 is optionally substituted phenyl; L is -(C=O)-, -SO2- or -(C=S)-; R1 is hydrogen, optionally substituted alkyl or acyl; and R2 is hydrogen or optionally substituted alkyl are useful phytopathogenic fungicides.

Fungicides

Use of compounds of general formula (I) or salts thereof as phytopathogenic fungicides wherein the various radicals and substituents are as defined in the description, pesticidal compositions containing them and method for combatting pests which comprises applying these.

Filament winding system

A filament winding system includes a head that selects the number of tows to be within a winding band while winding and positioning the winding band directly on the mandrel according to contours of the mandrel. Half of the tows are conveyed in an upper portion of the head and the remaining half are conveyed in a lower portion of the head with both halves meeting at an applicating roller at the discharge end of the tows. The head includes cut and add assemblies wherein the individual tows are selectively cut and later can be added to the band.

2-pyridylmethylamine derivatives useful as fungicides

Derivatives of 2-pyridylmethylamine useful as fungicides

Compounds of formula (I) and salts thereof as phytopathogenic fungicides wherein A<1> is substituted 2-pyridyl; A<2> is optionally substituted phenyl; L is -(C=O)-, -SO2- or -(C=S)-; R<1> is hydrogen, optionally substituted alkyl or acyl; and R<2> is hydrogen or optionally substituted alkyl are useful phytopathogenic fungicides.

2-pyridylmethylamine derivatives useful as fungicides

Compounds of formula (I) and salts thereof as phytopathogenic fungicides wherein A 1 is substituted 2-pyridyl; A 2 is optionally substituted phenyl; L is —(C═O)—, —SO 2 — or —(C═S)—; R 1 is hydrogen, optionally substituted alkyl or acyl; and R 2 is hydrogen or optionally substituted alkyl are useful phytopathogenic fungicides.

2-PYRIDYLMETHYLAMINE DERIVATIVES USE AS FUNGICIDES

DERIVATIVES OF 2-PIRIDYLMETHYLAMINE USEFUL AS FUNGICIDES.

Un compuesto de fórmula I, y sales del mismo, en donde A1 es un grupo 2-piridilo que tiene sustituyentes en la posición 3 y/o 5 que son elegidos independientemente unos de los otros como halógeno; hidroxi; ciano; nitro; SF5; trialquilsililo; un grupo amino sustituido opcionalmente con uno o dos grupos E o acilo, cada uno de los cuales puede ser igual o diferente; acilo; un grupo E, OE ó SE, en donde E es alquilo, alquenilo, alquinilo, cicloalquilo, cicloalquenilo, fenilo o heterociclilo, cada uno se los cuales se encuentra sustituido opcionalmente con halógeno, ciano, alcoxi, alquiltio, mercapto, hidroxi, nitro, amino, acilo, aciloxi, aciltio, fenilo, heterociclilo, feniltio, fenoxi, heterocicliloxi o heterocicliltio; o un grupo -C(E)=N-Q, en donde Q es E, OE, SE o un grupo amino sustituido opcionalmente con uno o dos grupos E o acilo, cada uno de los cuales puede ser igual o diferente; dos sustituyentes adyacentes, junto con los átomos a los que están unidos, pueden formar un anillo que puede contener hasta 3 heteroátomos; A2 es un fenilo que está sustituido opcionalmente con hasta 5 sustituyentes que se eligen, de forma independiente unos de otros, entre halógeno; hidroxi; ciano; nitro; SF5; trialquilsililo; un grupo amino sustituido opcionalmente con uno o dos grupos E o acilo, cada uno de los cuales puede ser igual o diferente; acilo; un grupo E, OE ó SE, en donde E es alquilo, alquenilo, alquinilo, cicloalquilo, cicloalquenilo, fenilo o heterociclilo, cada uno se los cuales se encuentra sustituido opcionalmente con halógeno, ciano, alcoxi, alquiltio, mercapto, hidroxi, nitro, amino, acilo, aciloxi, aciltio, fenilo, heterociclilo, feniltio, fenoxi, heterocicliloxi o heterocicliltio; o un grupo -C(E)=N-Q, en donde Q es E, OE, SE o un grupo amino sustituido opcionalmente con uno o dos grupos E o acilo, cada uno de los cuales puede ser igual o diferente; dos sustituyentes adyacentes, junto con los átomos a los que están unidos, pueden formar un anillo quepuede ...

Amidomethyl-substituted 2-(4-sulfonilamino)-3-hidroxy-3,4-dihydro-2h-chromium-6-yl-derivatives and drugs containing said compounds

The invention relates to compounds of general formula (I), wherein the meaning of R<1>, R<2>, R<3>, R<4>, R<5> and R<6> is given in a description, to a method for producing said compounds and to intermediate products thereof. Drugs containing the inventive compounds of formula (1) are also disclosed.

FILAMENT WINDING SYSTEM

Aminoalkyl-amidomethyl-substituted 2-(4-sulphonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl derivatives and their use as potassium channel blockers

Cardiovascular active compounds of the general formula (I), wherein R, R, R, R, R, R, R, R, R, R and n have the meanings given in the description, and also a process for the preparation of these compounds and intermediate products of this process are described. Furthermore, pharmaceutical compositions comprising the compounds of Formula (I) are specified.

Use of compounds, compost, pesticide composition, and, processes to combat phytopathogenic fungi and to prepare intermediate compounds

"USO DE COMPOSTOS, COMPOSTO, COMPOSIçãO PESTICIDA, E, PROCESSOS PARA COMBATER FUNGOS FITOPATOGêNICOS E PARA PREPARAR COMPOSTOS INTERMEDIáRIOS" Compostos com a fórmula (I) e sais dos mesmos como fungicidas fitopatogênicos, onde A¹ é 2-piridila substituída; A² é fenila opcionalmente substituída; L é -(C=O)-, -SO~ 2~- ou -(C=S)-; R¹ é hidrogênio, alquila opcionalmente substituída ou acila; e R² é hidrogênio ou alquila opcionalmente substituída, são úteis como fungicidas fitopatogênicos.

Fungicides

Filament winding system

0450p Alenskis, Geil, Gill, Moloney 1 FILAMENT WINDING SYSTEM Abstract of the Disclosure A filament winding system includes a head that selects the number of tows within a winding band while winding and positions the winding band directly on the mandrel according to its contours.

Aminoalkyl-amidomethyl-substituted 2-(4-sulphonylamino)-3-hydroxy-3 , 4-dihydro-2H-cromen-6-yl derivatives and their use as potassium channel blockers

Amidomethyl-substituierte 2-(4-sulfonilamino)-3- hidroxy-3,4-dihydro- 2h-chromen-6-yl-derivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Fungizide

Aminoalkylamidomethylsubstituierte 2-(4- sulfonylamino)-3-hydroxy-3,4-dihydro-2h-cromen- - yl derivate und ihre verwendung als kaliumkanalblocker

Fungizide verbindungen

Fungizide

Anomaly detection in wastewater networks

A computer complemented method for detecting anomalies e.g. blockages and leaks, at a wastewater asset e.g. a manhole, pumping station, of a wastewater i.e. sewer network, wherein the asset has a sensor configured to detect metrics associated with flow rate at the asset. The method acts on the sensed water flow data and current rainfall data from existing systems to provide an alert of an anomaly, by using machine learning, trained on historic flow and rainfall data, to predict max and min expected thresholds for flow metrics based on current rainfall data, and if the sensor measurements are outside these thresholds, during a predetermined duration, an alert is sent indicating an anomaly to a sewage network operator. This may improve the ability to efficiently manage a sewer network, preventing unnecessary inspection and/or reduce maintenance schedules, and allow specific maintenance to reduce use of overflows as a result of e.g. blockage, reducing risk of contamination of waterways. Also claimed is computer/system/program for carrying out the computer implemented method.

Anomaly detection for wastewater assets with pumps in wastewater networks

Methods, apparatus and systems are provided for detecting anomalies in a wastewater asset of a wastewater network. The wastewater asset comprising a wastewater pump system configured for pumping wastewater through the wastewater asset. The method comprising: receiving current environmental data comprising rainfall data associated with the wastewater asset, the current environmental data affecting the flow of wastewater through the wastewater asset, receiving wastewater pump measurements associated with pumping wastewater through the wastewater asset, applying the received current environmental data to a trained pump machine learning, ML, model configured for predicting minimum and maximum wastewater pump thresholds associated with pumping of wastewater through the wastewater asset, detecting an anomaly at the wastewater asset when one or more of multiple wastewater pump measurements at the wastewater asset at least exceeds the corresponding predicted maximum wastewater pump threshold and/or reaches below the corresponding predicted minimum wastewater pump threshold over an anomaly duration associated with the anomaly, and sending an indication of the detected anomaly at the wastewater asset to an operator monitoring the wastewater network.

Anomaly detection in wastewater networks

Methods, apparatus and systems are provided for detecting anomalies at a wastewater asset of a wastewater network. The wastewater asset comprising a sensor configured for performing measurements associated with wastewater flow through the wastewater asset. Current rainfall data associated with the wastewater asset is received. Receiving, from the sensor of the wastewater asset, real-time wastewater measurements associated with the wastewater flow at the wastewater asset. Applying the received current rainfall data to a trained machine learning model configured for predicting, in real-time, minimum and maximum thresholds associated with wastewater flow through the wastewater asset. Detecting an anomaly at the wastewater asset when one or more real-time wastewater measurements at the wastewater asset exceeds the corresponding predicted maximum wastewater threshold and/or reaches below the corresponding predicted minimum wastewater threshold over a time interval. Sending an indication of the detected anomaly at the wastewater asset to an operator monitoring the wastewater network.

Water ingress detection in wastewater networks

Methods, apparatus and/or systems are provided for detecting water ingress at a wastewater asset of a wastewater network For example, a method, apparatus and/or system configured to include: receiving a first set of time segments associated with a positive rate of change of a time series ground water level dataset associated with the wastewater asset; receiving a second set of time segments associated with negative rate of change of the time series ground water level dataset associated with the wastewater asset; applying a first set of time series rainfall data for the wastewater asset that is associated with the first set of time segments to a trained machine learning (ML) model configured for predicting a set of wastewater flow data associated with wastewater flow through the wastewater asset, where the trained ML model is trained based on a training dataset comprising historical wastewater measurement data for the wastewater asset that is associated with the second set of time segments and a second set of time series rainfall data for the wastewater asset that is associated with the second set of time segments; calculating a set of wastewater flow delta data for the wastewater asset based on the difference between a set of measured wastewater flow data for the wastewater asset that is associated with the first set of time segments and the predicted set of wastewater flow data; and detecting water ingress for the wastewater asset based on identifying those portions of the set of wastewater flow delta data associated with water ingress.

Irrigation lift pump