Occupancy sensing with vacate input

An occupancy sensing system includes a vacate input to cause the system to turn lights on without substantial delay when a monitored space becomes occupied after turning the load off in response to the vacate input. A special vacate input may be eliminated by determining, in response to a manual-off input, if the space has been vacated. A dead time may be included to prevent the lights from being turned back on by movement that is detected as occupants vacate the monitored space after pressing a vacate or manual-OFF button.

Bi-directional fill for use in cooling towers

Cooling towers and cooling tower fill configured for the cooling of process water with air by indirect heat exchange, in which the fill is configured with a first set of channels and a second set of channels, said first and second set of channels interleaved with one-another so that heat exchange occurs across material separating said channels from one-another.

Insulative boots and power distribution assemblies

A power distribution assembly includes a first conductor having a first conductor end and a first shape in cross-section and a second conductor having a second conductor end and a second shape in cross-section. A splice couples the first conductor end to the second conductor end. An insulative boot has a first opening of the first shape, wherein the insulative boot encompasses the first conductor end. The insulative boot also has a second opening having the second shape, wherein the second opening encompasses the second conductor end. The insulative boot has a cavity between the first end and the second end, wherein the cavity is configured to encompass the splice.

Rotary clamshell gate actuator for bulk material container

In accordance with presently disclosed embodiments, systems and methods for managing dry bulk material efficiently at a well site or other location are provided. Present embodiments are directed to a rotary clamshell gate actuation system and method, where the gate is separate from the one or more actuators used to open/close the gate. The disclosed system may include a portable bulk material container with a clamshell gate for easily dispensing material from the container. The system also includes a support structure equipped with one or more rotary actuators used to actuate the clamshell gate of the container between a closed and open position when the container is positioned on the support structure. The disclosed clamshell gate actuation system is easy to operate, low cost to manufacture, and reliable even when the portable container is not precisely aligned on the support structure.

Custom-fit dental guard

A dental guard (10) for preventing wear of the occlusal surfaces of a user's teeth resulting from bruxism is provided. The dental guard (10) can be can be custom-fitted to the teeth of the wearer. The guard (10) comprises a durable core (14) that is overmolded by a thermoplastic outer layer (12). The outer layer (12) can be softened through exposure to hot, but not boiling, water, and then formed around the user's teeth. The guard (10) may include one or more features (32, 84) that assist the user in proper positioning of the guard within his or her mouth during the custom fitting process.

Cell adhesion and extracellular matrix proteins

Various embodiments of the invention provide human cell adhesion and extracellular matrix proteins (CADECM) and polynucleotides which identify and encode CADECM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CADECM.

Medical pump with fixed stroke length

A method comprises measuring a volume of fluid delivered per pump stroke for each of a plurality of substantially identical medical pumps. The substantially identical medical pumps each have a fixed stroke length. The method further comprises: storing indications of the measured volumes on one or more data storage mediums; and for each of the plurality of substantially identical medical pumps, generating a separate therapy control program based on the indication of the measured volume associated with that one of the plurality of substantially identical medical pumps.

composition and method for preparing a composition

Solid oral dosage form containing an enhancer

The invention relates to a pharmaceutical composition and oral dosage forms comprising a bisphosphonate in combination with an enhancer to enhance intestinal delivery of the bisphosphonate to the underlying circulation. Preferably, the enhancer is a medium chain fatty acid or a medium chain fatty acid derivative having a carbon chain length of from 6 to 20 carbon atoms, and the solid oral dosage form is a controlled release dosage form such as a delayed release dosage form.

Solid oral dosage form containing an enhancer

The invention relates to a pharmaceutical composition and oral dosage forms comprising a DAC inhibitor in combination with an enhancer to promote absorption of the DAC inhibitor at the GIT cell lining. The enhancer can be a medium chain fatty acid or derivative thereof having a carbon chain length of from 6 to 20 carbon atoms. In certain embodiments, the solid oral dosage form is a controlled release dosage form such as a delayed release dosage form.

Compositions of gnrh related compounds and processes of preparation

The present invention provides compositions of GnRH related compounds that are suitable for oral administration, injectable administration and other forms of administration wherein the gelling characteristics of the composition are a factor. The compositions of the present invention comprise a therapeutically effective amount of one or more GnRH related compound, and a sufficient amount of at least one anti-gelling agents to reduce the gelation of the GnRH related compound. The present invention also provides processes for preparation of a composition of one or more GnRH related compound, wherein the process comprises mixing the GnRH related compound with one or more anti-gelling agents, wherein the anti-gelling agent comprises a medium chain fatty acid salt, or an ester, an ether, or a derivative of a medium chain fatty acid and has a carbon chain length of from about 4 to about 20 carbon atoms or is a surface active agent.

Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof

The present invention provides pharmaceutical compositions which are effective in providing therapeutically effective blood levels of a therapeutically active ingredient to a subject when administered to a gastrointestinal tract. In one aspect, the pharmaceutical compositions comprise a therapeutically effective amount of a therapeutically active ingredient; at least one water soluble enhancer, e.g., a medium chain fatty acid or a salt, ester, ether, or derivative of a medium chain fatty acid and has a carbon chain length of from about 4 to about 20 carbon atoms; and a saccharide.

Pharmaceutical compositions of selective factor Xa inhibitors for oral administration

The present invention provides pharmaceutical compositions for oral administration comprising a therapeutically effective amount of a selective factor Xa inhibitor or a pharmaceutically acceptable salt thereof and an enhancer, wherein the enhancer is a medium chain fatty acid or a salt, ester, ether, or derivative of a medium chain fatty acid and has a carbon chain length of from about 4 to about 20 carbon atoms. The present invention also provides a method for obtaining a reproducible bioavailability of selective factor Xa inhibitor in an object after oral administration comprising orally administering a pharmaceutical composition as described above.

Pharmaceutical compositions of iron for oral administration

The present invention generally relates to orally administered pharmaceutical compositions of iron compounds with medium chain fatty acid salts. The invention further relates to methods of using the pharmaceutical compositions to treat iron deficiency and related disorders.

Secreted proteins

The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

Secreted proteins

The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

Tobacco reconstitution process

Reconstituted Tobacco has ammonia incorporated therein. Tobacco is extracted with water to yield an insoluble portion and an aqueous portion containing water soluble tobacco components. The aqueous portion is contacted with ammonia to yield an ammoniated extract. The extract is applied to the insoluble portion which has been formed into a sheet-like shape. The resulting tobacco composition is dried to yield a reconstituted tobacco material treated with ammonia.

Tobacco reconstitution process

The process of the present invention involves extracting components from a tobacco material or other plant material using a solvent having an aqueous character to provide separately an aqueous tobacco extract and a water insoluble tobacco portion. The insoluble tobacco portion is refined and a slurry is produced. The slurry is formed into a predetermined shape, e.g., a formed web. The formed web can be pressed to reduce the moisture content. The tobacco material preferably has a moisture content of at least about 50 percent by weight. The material is contacted with an aqueous mixture of an aerosol precursor material. The ratio of liquid having an aqueous character to aerosol precursor material is typically from about 25 to 75 percent by weight. Immediately after the introduction of the aerosol precursor material, the web is dried at a preselected temperature so that the aerosol precursor material is dispersed evenly throughout the web.

Rapamycin formulations for oral administration

The present invention provides novel oral rapamycin formulations which have, per 100 ml of the formulation, from about 0.01 grams to about 5.0 grams of rapamycin, from about 0.05% to about 10% by volume of surfactant, and from about 75% to about 99.95% by volume of a solution of phospholipid or lecithin in which the phospholipid or lecithin therein is 40% to 75% by weight.

Transporters and ion channels

Various embodiments of the invention provide human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.

Printer having improved gas flow drop deflection

A drop generator operable to selectively form a drop having a first size and a drop having a second size from liquid emitted through a nozzle associated with the drop generator. The drop having the first size and the drop having the second size travel along a drop trajectory with the first size being larger than the second size when compared to each other. Each of the drops has a drop velocity. A gas flow deflection system includes a gas flow that is directed at a deflection zone that comprises at least a portion of the drop trajectory. The gas flow in the deflection zone includes a velocity vector having a parallel velocity component and a perpendicular velocity component with the parallel velocity component and the perpendicular velocity component being defined relative to the drop trajectory.

Low pressure, high temperature composite bridge plug

A low pressure, high temperature composite bridge plug. The bridge plug comprises a mandrel with a plurality of slips disposed therearound. A wedge is initially attached to said mandrel and in planar contact with the slips for forcing the slips radially outwardly into gripping engagement with a wellbore. An elastomeric sealing element is disposed on the mandrel and compressed between the wedge and a shoulder on the mandrel to expand the packing element radially outward into sealing engagement with the wellbore. A plurality of ratchets retained in a ratchet body grippingly engage the mandrel to prevent the plug from unsetting. The mandrel, slips, wedge and ratchet body are preferably made of non-metallic, composite materials for easy drilling.

Multiple zones frac tool

A device and a method are provided for the hydraulic fracturing of multiple zones in a well bore. A stinger carries a plurality of packers into a well bore. Each packer is separably connected to each adjacent packer. As each packer is sequentially secured in the well bore, the stinger is withdrawn from the secured packer and the process is repeated as the remaining packers are sequentially secured and separated.

Method and apparatus for efficient vertical fluid delivery for cooling a heat producing device

A heat exchanger and method of manufacturing thereof comprises an interface layer for cooling a heat source. The interface layer is coupled to the heat source and is configured to pass fluid therethrough. The heat exchanger further comprises a manifold layer that is coupled to the interface layer. The manifold layer includes at least one first port that is coupled to a first set of individualized holes which channel fluid through the first set. The manifold layer includes at least one second port coupled to a second set of individualized holes which channel fluid through the second set. The first set of holes and second set of holes are arranged to provide a minimized fluid path distance between the first and second ports to adequately cool the heat source. Preferably, each hole in the first set is positioned a closest optimal distance to an adjacent hole the second set.

Systems and methods for managing diabetes care data

A host-client data sharing system manages diabetes care data. A host database, preferably web or internet based, is implemented for storing diabetes care data relating to multiple diabetics. A client or local database stores the diabetes care data relating to multiple diabetics on a personal appliance such as a PC, or a portable or handheld microprocessor-based computing device. The host database uses multiple servers for handling client interactions with the system.

Systems and methods for managing diabetes care data

A host-client data sharing system manages diabetes care data. A host database, preferably web or internet based, is implemented for storing diabetes care data relating to multiple diabetics. A client or local database stores the diabetes care data relating to multiple diabetics on a personal appliance such as a PC, or a portable or handheld microprocessor-based computing device. The host database uses multiple servers for handling client interactions with the system.

Cigarette

A cigarette comprises a blend of tobacco materials. The blend includes volume expanded flue-cured tobacco cut filler and a reconstituted tobacco material in cut filler form. The reconstituted tobacco material includes calcium carbonate and tobacco parts which are formed into a sheet-like shape using a papermaking process. The cigarette can include a filter element provided from a non-woven polypropylene web, glycerin and a water soluble tobacco extract. Such a cigarette can generate low levels of visible sidestream smoke.

Camera housing for reducing internal reflections

A camera includes a camera housing with a housing wall demarcating the interior of the camera housing, an optical aperture and a lenslet aperture extending through the housing wall, and an opaque blocking wall adjoined to and extending inwardly from the housing wall and circumscribing the lenslet aperture; a lenslet in the lenslet aperture aligned with an on- camera light source; a lens contained within the camera housing and aligned with the optical aperture to receive light entering the camera housing through the optical aperture; an imager within the camera housing and aligned with the lens to capture light passing through the lens; and circuitry contained within the camera housing communicative with the imager and operable to operate the camera. The circuitry includes a printed circuit board that abuts the opaque blocking wall and on which is mounted a light source positioned to be circumscribed by the opaque blocking wall.

Camera housing for reducing internal reflections and camera comprising same

A camera includes a camera housing with a housing wall demarcating the interior of the camera housing, an optical aperture and a lenslet aperture extending through the housing wall, and an opaque blocking wall adjoined to and extending inwardly from the housing wall and circumscribing the lenslet aperture; a lenslet in the lenslet aperture aligned with an on-camera light source; a lens contained within the camera housing and aligned with the optical aperture to receive light entering the camera housing through the optical aperture; an imager within the camera housing and aligned with the lens to capture light passing through the lens; and circuitry contained within the camera housing communicative with the imager and operable to operate the camera. The circuitry includes a printed circuit board that abuts the opaque blocking wall and on which is mounted a light source positioned to be circumscribed by the opaque blocking wall.

Camera housing for reducing internal reflections and camera comprising same

A camera includes a camera housing with a housing wall demarcating the interior of the camera housing, an optical aperture and a lenslet aperture extending through the housing wall, and an opaque blocking wall adjoined to and extending inwardly from the housing wall and circumscribing the lenslet aperture; a lenslet in the lenslet aperture aligned with an on-camera light source; a lens contained within the camera housing and aligned with the optical aperture to receive light entering the camera housing through the optical aperture; an imager within the camera housing and aligned with the lens to capture light passing through the lens; and circuitry contained within the camera housing communicative with the imager and operable to operate the camera. The circuitry includes a printed circuit board that abuts the opaque blocking wall and on which is mounted a light source positioned to be circumscribed by the opaque blocking wall.

Electroosmotic microchannel cooling system

Apparatus and methods according to the present invention preferably utilize electroosmotic pumps that are capable of generating high pressure and flow without moving mechanical parts and the associated generation of unacceptable electrical and acoustic noise, as well as the associated reduction in reliability. These electroosmotic pumps are preferably fabricated with materials and structures that improve performance, efficiency, and reduce weight and manufacturing cost relative to presently available micropumps. These electroosmotic pumps also preferably allow for recapture of evolved gases and deposited materials, which may provide for long-term closed-loop operation. Apparatus and methods according to the present invention also allow active regulation of the temperature of the device through electrical control of the flow through the pump and can utilize multiple cooling loops to allow independent regulation of the special and temporal characteristics of the device temperature profiles. Novel microchannel structures are also described.

Protein modification and maintenance molecules

Various embodiments of the invention provide human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.

Protein modification and maintenance molecules

Various embodiments of the invention provide human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.

Scratch-resistant strippable finish

A jobsite-applied radiation curable floor finish containing inorganic particles can be applied to a multipiece flooring material whose pieces have a top surface, a side surface or surfaces and gaps between pieces. The top surface is coated and at least the uppermost portion of the gaps are filled with a layer or layers of cured finish composition comprising radiation cured polymer and sufficient inorganic filler particles to impart increased scratch resistance to the cured finish. The finish can also be applied as a strip agent-permeable coating atop a strippable intermediate coating atop a substrate.

Partially acrylated epoxy compositions curable under the action of an amine.

Rapamycin formulations for oral administration

ABSTRACT OF THE DISCLOSURE The present invention comprises novel oral rapamycin formulations which have, per 100 ml of formulation, from about 0.05 to about 10.0 grams of rapamycin, from about 0.1 to about 25 ml of N,N-dimethylacetamide, from about 0.1 to about 10 ml of surfactant, and from about 65 to about 99.8 ml of PEG 400.

Partially acrylated epoxy compositions curable under the action of an amine.

L'invention se rapporte à des compositions durcissables sous l'action d'une amine contenant une résine époxy partiellement acrylée utiles pour former des revêtements protecteurs et/ou décoratifs sur une variété de substrats, en particulier des substrats de sols. The invention relates to compositions curable under the action of an amine containing a partially acrylated epoxy resin useful for forming protective and / or decorative coatings on a variety of substrates, in particular soil substrates.

Rapamycin formulations for oral administration

The present invention comprises novel oral rapamycin formulations which contain, per each 100 ml of the formulation, from about 0.01 to about 10.0 grams per 100 ml of rapamycin, from about 0.1 to about 10 ml of surfactant, from about 0.1 to about 25 ml of N,N-dimethylacetamide, and from about 65 to about 99.8 ml of a lecithin or phospholipid solution.

Intracellular signaling molecules

Various embodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expressionof INTSIG.

Secreted proteins

The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention al so provides methods for diagnosing, treating, or preventing disorders associate d with aberrant expression of SECP.

Menthone enhancement of transdermal drug delivery

Disclosed herein are compositions and methods for enhancing the transdermal delivery of physiologically active agents across mammalian skin or membranes and which comprise a percutaneous transfer enhancing amount of 1-menthone and a drug.

Secreted proteins

Various embodiments of the invention provide human secreted proteins (SECP) and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

Receptors and membrane-associated proteins

Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.

Secreted proteins

The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

Cell adhesion and extracellular matrix proteins

Various embodiments of the invention provide human cell adhesion and extracellular matrix proteins (CADECM) and polynucleotides which identify and encode CADECM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CADECM.

Saw filer and gummer.

Method for isolation of new antibiotic

Receptors and membrane-associated proteins

The invention provides human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, o r preventing disorders associated with aberrant expression of REMAP.

Extracellular messengers

Various embodiments of the invention provide human extracellular messengers (EXMES) and polynucleotides which identify and encode EXMES. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of EXM ES.

Elliptically finned heat exchanger comprising indirect and direct heat exchange sections

Spiral finned elliptical tube closed circuit coolers and evaporative refrigerant condensers in which the air flow entering the unit is directed to flow across the tubes in a direction that is parallel to the tube axes and generally perpendicular to the fins produce a completely unexpected gain in capacity of 25% compared to comparable units in which the air flow is directed across/perpendicular to the tube axes.

Specimen collector

Motorized propulsion system for a bed

According to the present disclosure, a propulsion system (24, 224, 324) is provided to assist a caregiver in moving a patient support (10) about a care facility. Propulsion system (24, 224, 324) is detachably coupled to patient support (10) to permit storage of propulsion system (24, 224, 324) or use of propulsion system (24, 224, 324) on multiple patient supports (10).

Polymeric compositions and method of shaping same

Mobile support structure for bulk material containers

In accordance with presently disclosed embodiments, systems and methods for efficiently managing bulk material are provided. The disclosure is directed to a portable support structure used to receive one or more portable containers of bulk material and output bulk material from the containers directly into the blender hopper. The portable support structure may include a frame for receiving and holding the one or more portable bulk material containers in an elevated position proximate the blender hopper, as well as one or more gravity feed outlets for routing the bulk material from the containers directly into the blender hopper. In some embodiments, the portable support structure may be transported to the well site on a trailer, unloaded from the trailer, and positioned proximate the blender unit. In other embodiments, the portable support structure may be a mobile support structure that is integrated into a trailer unit.

Structural and cytoskeleton-associated proteins

Various embodiments of the invention provide human structural and cytoskelet on- associated proteins (SCAP) and polynucleotides which identify and encode SCA P. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SCAP.

Proteins associated with cell growth, differentiation, and death

The invention provides human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides which identify and encode CGDD. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. THe invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.

Secreted proteins

Various embodiments of the invention provide human secreted proteins (SECP) and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

Formulations providing three distinct releases

A therapeutic preparation consisting of three groups of spheroids containing an active medicinal substance. The first group of spheroids is uncoated and rapidly disintegrates upon ingestion to release an initial dose of medicinal substance a second group of spheroids is coated with a pH sensitive coat to provide a second dose and a third group of spheroids is coated with a pH independent coat to provide a third dose. A powder blend of active medicinal substance may be substituted for the first group of uncoated spheroids. The therapeutic preparation may be utilized as a mixture of groups of spheroids in a capsule.

Process for recovery of metal ions

A process of selectively separating a target metal contained in an aqueous solution by contacting the aqueous solution containing a target metal with a n aqueous solution including a water-soluble polymer capable of binding with t he target metal for sufficient time whereby a water-soluble polymer-target meta l complex is formed, and, separating the solution including the water-soluble polymer-target metal complex from the solution is disclosed.

Low pressure, high temperature composite bridge plug

A low pressure, high temperature composite bridge plug. The bridge plug comprises a mandrel with a plurality of slips disposed therearound. A wedge is initially attached to said mandrel and in planar contact with the slips for forcing the slips radially outwardly into gripping engagement with a wellbore. An elastomeric sealing element is disposed on the mandrel and compressed between the wedge and a shoulder on the mandrel to expand the packing element radially outward into sealing engagement with the wellbore. A plurality of ratchets retained in a ratchet body grippingly engage the mandrel to prevent the plug from unsetting. The mandrel, slips, wedge and ratchet body are preferably made of non-metallic, composite materials for easy drilling.

Motorized propulsion system for a bed

According to the present disclosure, a propulsion system (24, 224, 324) is provided to assist a caregiver in moving a patient support (10) about a care facility. Propulsion system (24, 224, 324) is detachably coupled to patient support (10) to permit storage of propulsion system (24, 224, 324) or use of propulsion system (24, 224, 324) on multiple patient supports (10).

Method and apparatus for conduit extrusion

An extrusion assembly includes a stationary housing section, and an outer die and mandrel for defining an annular passageway centered about an axis The outer die and mandrel are held stationary against rotational motion about the axis. A rotor is rotationally supported within the housing, for rotational motion about the axis. The rotor includes a melt channel for rotationally conveying an extrusion to the annular passageway, so as to form a helically-wound conduit that advances linearly through the annular passageway.

Molecules for disease detection and treatment

Various embodiments of the invention provide human molecules for disease detection and treatment (MDDT) and polynucleotides which identify and encode MDDT. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MDDT.

Transporters and ion channels

Various embodiments of the invention provide human transporters andion channels (TRICH) and polynucleotides which identify and encode TRICH. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.

Scratch-resistant strippable finish

Methods and devices for reducing myopia in children

Methods and devices for treating a human child having myopia are disclosed. A method for reducing progression of myopia in a child having, or suspected of having, myopia, comprises: treating the child with spectacles comprising at least one myopia control spectacle lens having a single vision region and a myopia control region, wherein the myopia control spectacle lens comprises: (i) a clear aperture, (ii) an annular region surrounding the clear aperture, the annular region comprising one or more features that reduce the visual acuity for the corresponding eye, and (iii) a transition zone between the clear aperture and the annular region. Both (i) and (ii) are substantially centered on a lens axis, the clear aperture corresponding to the single vision region and the annular region corresponding to the myopia control region. The method reduces myopia progression in the human child by 0.4 D or more after three years of treatment.

Pipe joint construction and coupling therefor

A pipe joint and coupling construction particularly suited for joining large diameter plastic pipe as used in sewer relining. The construction comprises first and second sections of cylindrical pipe having axially aligned opposed end walls with a continuous groove formed in each end wall. The groove in each end wall is axially aligned with the groove in the opposed end wall and cooperates therewith to form a gasket receiving chamber. The coupling member is adapted to be mounted in the gasket receiving chamber for sealingly joining the pipe sections. It comprises a rigid annular core ring for mounting in the chamber to extend axially into each of the axially aligned grooves. A resilient compressible elastomeric covering is positioned over the core ring and carried circumferentially continuous radially extending protrusions which are sized to be sealingly compressed between the core ring and the side walls of the grooves.

Enzymes

Structural and cytoskeleton-associated proteins

Various embodiments of the invention provide human structural and cytoskeleton-associated proteins (SCAP) and polynucleotides which identify and encode SCAP. Embodiments of te invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing discorders associated with aberrant expression of SCAP.

Transporters and ion channels

Various embodiments of the invention provide human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.

Modular medical pump assembly

A medical pump subassembly comprises a magnetic cup forming a recess. The magnetic cup includes a protrusion within the recess. The cup forms a central aperture through the protrusion. The medical pump subassembly further comprises an electromagnetic coil within the recess and circumscribing the protrusion, a weld ring surrounding the recess, a barrier plate covering the recess, and a seal between the weld ring and the barrier plate to fluidically separate an interior of the cup from an external surface of the barrier plate.

Method and system for processing transactions

A system and method is provided for processing transactions between at least one buying company and at least one selling company which results in the creation of a new collaborative data set. In one embodiment, the method comprises providing a central datastore accessible to users from the buying company and users from the selling company. Purchase order and invoice data are obtained and compared via a computer, to identify a matched record having purchase order data and corresponding invoice data. A collaborative data set in the central datastore is created, based in part on the matched record and storing in the datastore detailed settlement data regarding settlement of the matched record of purchase order data and corresponding invoice data. The method stores a complete settlement transaction history by providing for storage of additional settlement data in the central datastore, wherein credit memos, debit memos regarding the invoice, the purchase order of the matched record, and/or other documents related to the transaction are stored as part of the collaborative data set.

Cytoskeletion-associated proteins

Electroosmotic microchannel cooling system

Molecules for disease detection and treatment

The invention provides human molecules for disease detection and treatment (MDDT) and polynucleotides which identify and encode MDDT. The invention als o provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, o r preventing disorders associated with aberrant expression of MDDT.

Nursing-bottle nipple.

Pharmaceutical compositions of iron for oral administration

The present invention generally relates to orally administered pharmaceutical compositions of iron compounds with medium chain fatty acid salts. The invention further relates to methods of using the pharmaceutical compositions to treat iron deficiency and related disorders.

Luminair

Method of hormonal therapy

The present invention combines the administration of estrogens with the administration of non-aromatizing androgens to treat frailty in women undergoing estrogen replacement therapy.

Enzymes

Various embodiments of the invention provide human enzymes (ENZM) and polynucleotides which identify and encode ENZM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ENZM.

Synthesis of a mixture of sulfated estrogens using a sulfur trioxide complex

A process of producing a stable composition comprising a mixture of sulfated estrogens. The mixture of sulfated estrogens may comprise sulfated alkali metal salts of .DELTA.8,9-dehydroestrone, estrone, and derivatives thereof or other estrogens. The process comprises the steps of sulfating such mixture of alkali metal salts of .DELTA.8,9-dehydroestrone, estrone, and derivatives thereof with a sulfur trioxide complex and adding tris(hydroxymethyl)aminomethane.

Step-down estrogen therapy

Ultra-miniature accelerometers

Nucleic acid-associated proteins

Method and system for processing transactions

The present invention discloses a system and method for processing business transactions between trading partners using a central interactive platform. The processing may include comparing purchase order data (12, 18) and invoice data (14, 20) to identify matching information and non-matching information. If the information matches, the invoices (14, 20) are processed for payment. If the information does not match, the discrepancies are identified to the buying company or the selling company for resolution (38).

Process for recovery of metal ions

A process of selectively separating a target metal contained in an aqueous solution by contacting the aqueous solution containing a target metal with an aqueous solution including a water-soluble polymer capable of binding with the target metal for sufficient time whereby a water-soluble polymer-target metal complex is formed, and, separating the solution including the water-soluble polymer-target metal complex from the solution is disclosed.

Method of manufacture and design of cast-in-place valve seats

A cylinder head having a cast-in-place valve seat for an automobile vehicle includes a valve seat having an inner wall. At least one retaining feature integrally and homogeneously extends from the inner wall. The valve seat when positioned into a casting mold has the at least one retaining feature assisting in retaining the valve seat in the casting mold. A metal in a molten form is received in the casting mold. A cast component formed after cooling of the metal has the valve seat cast-in-place.

Transporters and ion channels

Various embodiments of the invention provide human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.

Molecules for disease detection and treatment

The invention provides human molecules for disease detection and treatment (MDDT) and polynucleotides which identify and encode MDDT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MDDT.

Wideband high impedance bridging module

A bridge module provides connection between first and second conductors of a line under test and a test instrument adapted for use with the bridge module. The bridge module provides monitoring and measurement of DSL communication signals between the telephone company DSL terminal (DSLAM) and the subscriber home DSL equipment across a wide range of frequencies. The bridge module can be used at any point in the communications link and can be used while the link is active. The bridge module provides a clickless connection to the active DSL communications link to avoid interruption in DSL service.

Method of vulcanizing rubber and the like

Radiation delivery system and method

A radiation delivery system and method are described. The system includes a treatment configuration such as a stent, balloon catheter, wire, ribbon, or the like, a portion of which is covered with a gold layer. Chemisorbed to the gold layer is a radiation-emitting self-assembled monolayer or a radiation-emitting polymer. The radiation delivery system is compatible with medical catheter-based technologies to provide a therapeutic dose of radiation to a lesion following an angioplasty procedure.

Tunnel effect measuring systems and particle detectors

Methods and apparatus for measuring gravitational and inertial forces, magnetic fields, or wave or radiant energy acting on an object or fluid in space provide an electric tunneling current through a gap between an electrode and that object or fluid in space and vary that gap with any selected one of such forces, magnetic fields, or wave or radiant energy acting on that object or fluid. These methods and apparatus sense a corresponding variation in an electric property of that gap and determine the latter force, magnetic fields, or wave or radiant energy in response to that corresponding variation, and thereby sense or measure such parameters as acceleration, position, particle mass, velocity, magnetic field strength, presence or direction, or wave or radiant energy intensity, presence or direction.

Electroosmotic pump apparatus

An electroosmotic pump apparatus (300) that pumps a fluid having a liquid phase upon application of a voltage comprising: a fluid chamber (312) having a fluid inlet (322) and a fluid outlet (324); an anode (314) disposed within an anode chamber portion (312b); a cathode (316) disposed within a cathode chamber portion (312a); a porous structure (310) that provides electroosmotic pumping upon application of the voltage between the anode (314) and the cathode (316), the porous structure (310) creating a partition in the fluid chamber (312) between the anode chamber portion (312b) and the cathode chamber portion (312a); and a catalytic recombiner (326) integrated with the fluid chamber (312).

Method of forming chamfered spigot end on pipe

METHOD OF FORMING CHAMFERED SPIGOT END ON PIPE Abstract A method of forming a chamfered and sealed end on a spiral wound plastic pipe of the type including at least a pair of radially spaced circumferential side walls connected by an intermediate wall which joins generally radially between the side walls and extends in a helical path axially of the pipe. The method includes determining the desired axial length of the chamfer and removing the intermediate wall which lies between the side walls axially inwardly of the end of the pipe a distance substantially equal to the desired length to define an outwardly open channel between the side walls. Thereafter one of the side walls is permanently deflected to bring it substantially into engagement with the end of the other of the side walls circumferentially about the pipe to thereby form a chamfer on the end of the pipe.

Apparatus for making hollow rubber articles, such as nipples, finger cots, bulbs, and the like

Molecules for disease detection and treatment

Thermal capacity of elliptically finned heat exchanger

Spiral finned elliptical tube closed circuit coolers and evaporative refrigerant condensers in which the air flow entering the unit is directed to flow across the tubes in a direction that is parallel to the tube axes and generally perpendicular to the fins produce a completely unexpected gain in capacity of 25% compared to comparable units in which the air flow is directed across/perpendicular to the tube axes.

Solid Oral Dosage Form Containing An Enhancer

The invention relates to a pharmaceutical composition and oral dosage forms comprising a bisphosphonate in combination with an enhancer to enhance intestinal delivery of the bisphosphonate to the underlying circulation. Preferably, the enhancer is a medium chain fatty acid or a medium chain fatty acid derivative having a carbon chain length of from 6 to 20 carbon atoms, and the solid oral dosage form is a controlled release dosage form such as a delayed release dosage form.

Automatic record changing phonograph