Berührungsloses Messsystem und Sensorgerät mit einer auf einem mikro-elektro-mechanischen System basierenden Lichtquelle

Ein berührungsloses Messsystem zum Erhalten von dreidimensionalen Profilinformationen, umfassend:ein Lichtquellensubsystem, welches ausgebildet ist, um einen Lichtpunkt in einer Beleuchtungsregion abzutasten;ein erstes Abbildungsgerät mit einem Bildfeld, welches so angeordnet ist, um sich mit der Beleuchtungsregion zu überschneiden und ausgebildet ist, um Bilddaten aufzunehmen;ein erstes Kontrollmodul, welches in Datenkommunikation mit dem ersten Abbildungsgerät steht, wobei das erste Kontrollmodul ausgebildet ist, um die Position eines Objektes in dem Bildfeld des ersten Abbildungsgerätes von den aufgenommenen Bilddaten zu ermitteln und die Position des Objektes in einem allgemeinen Koordinatensystem anzuzeigen, wobei der Lichtpunkt durch das Lichtquellensubsystem mit einer höheren Abtastgeschwindigkeit als die Shuttergeschwindigkeit des ersten Abbildungsgeräts abgetastet wird;ein zweites Abbildungsgerät mit einem Bildfeld, welches so angeordnet ist, um sich mit der Beleuchtungsregion ...

NACHBEHANDLUNGSSYSTEM

Ein Nachbehandlungssystem umfasst einen selektiven katalytischen Reduktionskatalysator (SCR-Katalysator) (200), der in das in Strömungsrichtung oberhalb gelegene Ende (168) einer Hülse (166) eingeführt werden kann. Der SCR-Katalysator (200) weist eine Substratmatrix (210) mit katalytischem Material (214) auf, welche sich zwischen einer ersten Fläche bzw. Stirnseite (220) und einer zweiten Fläche bzw. Stirnseite (222) erstreckt. Ein Mantel (230) ist um die Substratmatrix (210) angebracht und erstreckt sich zwischen einem ersten Rand (232) nahe der ersten Stirnfläche (220) und einem zweiten Rand (234) nahe der zweiten Stirnfläche (222). Der Mantel (230) kann eine überhängende Erweiterung (240) aufweisen, welche den ersten Rand (232) des Mantels (230) über die erste Stirnfläche (220) der Substratmatrix (210) hinaus erweitert. Um eine Entnahme des SCR-Katalysators (200) aus der Hülse (166) zu erleichtern ist eine Entnahmehilfe (252) auf der leicht zugänglichen inneren Oberfläche (242) der überhängenden ...

Vorrichtung zum Herstellen eines Verbundgussteiles

Vorrichtung zum Herstellen eines Verbundgussteiles, insbesondere einer Verbundgussbremsscheibe für Scheibenbremsen von Kraftfahrzeugen, mit einem, insbesondere in einer verlorenen Form gegossenen, ringförmigen Bauteil (12) aus höherschmelzendem Werkstoff und radial nach innen ragenden Mitnehmern (14), die beim nachfolgenden Gießen eines nabenförmigen Gussteiles (16) aus niedriger schmelzendem Werkstoff in einer in zwei Formhälften (20, 22) unterteilten Dauerform umgießbar sind, wobei das Bauteil (12) in die untere Formhälfte (20) der Dauerform einlegbar ist und durch Aufsetzen der oberen Formhälfte (22) die Mitnehmer (14) umschließbar ist, wobei die Teilungsebene (11) der Dauerform mit der im wesentlichen in einer Rotationsmittelebene liegenden Teilungsebene (11) des Bauteiles (12) zusammenfällt, dadurch gekennzeichnet, dass die Vorrichtung eine Aufspannplatte mit symmetrisch umfangsverteilten Zentrierungsschiebern (28) aufweist, die parallel zur Teilungsebene (11) der Dauerform verschiebbar ...

Motorsteuersystem für Verbrennungsmotoren

Motorsteuersystem, umfassend:ein Moduswahlmodul (322), das ausgestaltet ist, um auf der Grundlage einer Motordrehzahl (RPM) und einer Fahrereingabe (T) einen Betriebsmodus (M) aus einem Steuermodus mit offenem Regelkreis, einem Drehmomentregelmodus und einem Drehzahlregelmodus zu wählen;ein Achsdrehmoment-Entscheidungsmodul (ABA-Modul) (226), das ABA-Anforderungen für ein vorhergesagtes (Tatam) und unmittelbares (Tatam) Drehmoment auf der Grundlage der Fahrereingabe (T) erzeugt;ein Drehzahlregelmodul (SC-Modul) (230), das einen ersten Satz von SC-Anforderungen für ein vorhergesagtes (Trpm) und unmittelbares (Trpm) Drehmoment auf der Grundlage der Motordrehzahl (RPM) erzeugt;ein Vortriebsdrehmoment-Entscheidungsmodul (PTA-Modul) (228), das PTA-Anforderungen für ein vorhergesagtes und unmittelbares Drehmoment beruhend auf entweder den ABA-Anforderungen für ein vorhergesagtes (Tatam) und unmittelbares (Tatam) Drehmoment oder auf dem ersten Satz von SC-Anforderungen für ein vorhergesagtes ( ...

Adaptive Motordrehzahlsteuerung zum Verhindern des Schlingerns und Abwürgen eines Motors

Verfahren zur adaptiven Motordrehzahlsteuerung, das umfasst, dass:ermittelt wird, ob sich ein Motor (14) im Leerlauf befindet;eine Motordrehzahlabweichung als eine Differenz zwischen einer Ist-Motordrehzahl (404) und einer Soll-Motordrehzahl ermittelt wird, wobei die Soll-Motordrehzahl einer angewiesenen Motordrehzahl entspricht;eine Frequenz anhand einer Häufigkeit ermittelt wird, mit der die Motordrehzahlabweichung innerhalb einer vorbestimmten Zeitdauer ihr Vorzeichen wechselt;ein Motorschlingerzustand detektiert wird, wenn der Betrag der Motordrehzahlabweichung größer als ein vorbestimmter Abweichungsschwellenwert ist und die Frequenz größer als ein vorbestimmter Frequenzschwellenwert ist; undeine Drehmomentreserve und/oder die Soll-Motordrehzahl basierend auf der Ermittlung, ob sich der Motor (14) im Leerlauf befindet, und basierend auf dem detektierten Motorschlingerzustand angepasst werden, wobei die Drehmomentreserve einem Betrag eines reservierten Drehmoments zum Ansprechen auf ...

Adaptive Motordrehzahlsteuerung zum Verhindern des Schlingerns und Abwürgen eines Motors

Ein adaptives Motordrehzahlsteuersystem umfasst ein Leerlaufzustandsmodul, das ermittelt, ob sich der Motor im Leerlauf befindet, und das ermittelt, ob sich eine Ist-Motordrehzahl von einer Soll-Motordrehzahl unterscheidet. Die Soll-Motordrehzahl entspricht einer angewiesenen Motordrehzahl. Ein Drehmomentreserve-Ermittlungsmodul passt eine Drehmomentreserve und/oder die Soll-Motordrehzahl basierend auf der Ermittlung, ob sich der Motor im Leerlauf befindet, und basierend auf der Ermittlung an, dass sich die Ist-Motordrehzahl von der Soll-Motordrehzahl unterscheidet. Die Drehmomentreserve entspricht einem Betrag eines reservierten Drehmoments zum Ansprechen auf eine erwartete zukünftige Last an dem Motor.

KATALYSIERTES FILTER ZUM BEHANDELN VON ABGAS

Beschrieben wird ein Dieselpartikelfilter mit der Fähigkeit, Ruß aus einem Abgas während eines Betreibens des Filters bei niedrigem Rückdruck zu entfernen, wobei das Filter a) ein Wandstromfiltersubstrat mit einer mittleren Porengröße, einer Einlassseite, einer Auslassseite und einem porösen Inneren zwischen der Einlassseite und der Auslassseite und b) eine von der Auslassseite des Substrats her aufgetragene Katalysatorzusammensetzung umfasst, wobei die Katalysatorzusammensetzung eine d50-Teilchengrößenverteilung aufweist, wobei die d50-Teilchengrößenverteilung größer als oder gleich der mittleren Porengröße geteilt durch 4,9 ist und wobei die Einlassseite im Wesentlichen frei von einer Katalysatorbeschichtung ist.

EINSATZ DER UMWANDLUNG VON HPLV-LUFT IN LVHP-LUFT FÜR DEN ANTRIEB VON PATIENTENTRANSPORTEINRICHTUNGEN

Systeme für die Lagerung, die Bilderfassung oder den Transport eines Patienten umfassen eine Modalität mit einer zur Lagerung eines Patienten eingerichteten Auflagefläche, einen der Modalität zugeordneten Konverter, wobei der Konverter eingerichtet ist, RLVHP-Luft (RLVHP = Relatively Low-Volume High-Pressure = relativ Niedervolumen-Hochdruck) von einer RLVHP-Luftquelle zu empfangen und die RLVHP-Luft in RHVLP-Luft (RHVLP = Relatively High-Volume Low-Pressure = relativ Hochvolumen-Niederdruck) umzuwandeln, sowie ein Luftstromgerät, das eingerichtet ist, die RHVLP-Luft vom Konverter zu empfangen und an der Modalität eine Luftstromfunktion unter Einsatz der RHVLP-Luft bereitzustellen.

Roboterwerkzeugwechsler mit Werkzeuggestell-Entkopplungs-Spannungsversorgung

Ein Roboterwerkzeugwechsler (10) stellt einen inhärent sicheren Betrieb sicher, indem Leistungsquellen für die „Kopplungs-„ und „Entkopplungs-„ Vorgänge seiner Kopplungsmechanismen (16) getrennt sind. Die Leistung für den Entkopplungsvorgang ist nur verfügbar, wenn ein angebrachtes Roboterwerkzeug sicher in seinem Werkzeuggestell (48) angeordnet ist. Wenn das Roboterwerkzeug einmal das Werkzeuggestell (48) verlässt, wird dem Kopplungsmechanismus (16) des Roboterwerkzeugwechslers (10) keine Leistung zugeführt, um das Roboterwerkzeug von einem Roboterarm zu entkoppeln. Dementsprechend ist es unmöglich für das Roboterwerkzeug, unabsichtlich außer Eingriff von dem Roboterarm zu kommen – sogar wenn eine Software fälschlicherweise ein ENTKOPPLUNGS-Signal einschalten würde oder anderweitig einen Entkopplungsvorgang initiieren würde. Da der Entwurf inhärent sicher ist, sind darüber hinaus weder Verriegelungs-Schaltungen, die Redundanz solcher Schaltungen noch die umfangreichen und komplexen Beobachtungsschaltungen ...

ZIELVERBUNDKERNVORRICHTUNG FÜR RADIALSTRÖMUNGSGEOMETRIE

Zur Optimierung der Effizienz eines Perforationswerkzeugsystems können Bohrlochbedingungen simuliert werden, um die optimale Konfiguration für das Perforationswerkzeugsystem zu bestimmen. Ein simuliertes Bohrloch ist in einem Druckbehälter angeordnet und mit einer Zielverbundkernanordnung gekoppelt. Ein Perforationswerkzeugsystem ist in dem simulierten Bohrloch über der Zielverbundkernanordnung angeordnet. Die Zielverbundkernanordnung umfasst eine äußere Hülle. Die äußere Hülle umfasst ein Material, das eine Gummiblase oder einen flexiblen Mantel abstützt, die bzw. der um die äußere Hülle angeordnet ist. Die äußere Hülle isoliert das Überlagerungsfluid und den Druck von dem inneren Kern während eines Radialströmungstests, um Bedingungen im Bohrloch genauer zu simulieren. Ein Parameter eines Perforationswerkzeugsystems kann zumindest teilweise auf Grundlage eines Ergebnisses des Radialströmungstests geändert werden.

Ladungsprüfsystem für Ladungen zum Perforieren von unter Spannung stehendem Gestein

Hohlladungen, die in Bohrlochperforationsvorgängen verwendet werden, können mit einem Ladungsprüfsystem zum Perforieren von unter Spannung stehendem Gestein geprüft werden. Das System beinhaltet eine Hohlladungsprüfkammer. Die Hohlladungsprüfkammer kann einen Lade- und Auswurfkolben und eine Kernprobenkammer beinhalten. Die Kernprobenkammer steht in mechanischer Verbindung mit dem Lade- und Auswurfkolben und ist dazu abgemessen, eine Kernprobe aufzunehmen. Die Hohlladungsprüfkammer beinhaltet auch einen Kernprobenspannungsapplikator, um die Kernprobe unter Spannung zu setzen. Ferner beinhaltet das System einen Auswurfmechanismus benachbart zur Hohlladungsprüfkammer, um eine Auswurfkraft am Lade- und Auswurfkolben bereitzustellen.

REGELANTRIEB FÜR EINEN GENERATOR

Es wird ein variables Antriebssystem eines Leistungssystems offenbart. Das variable Antriebssystem kann einen Motorzahnradsatz beinhalten, um Leistung von einem Motorausgang eines Motors auf eine variable Eingangsantriebswelle des variablen Antriebssystems zu übertragen. Das variable Antriebssystem kann einen Generatorzahnradsatz beinhalten, um Leistung, die durch den Motor erzeugt wird, auf eine Generatorantriebswelle eines Generators zu übertragen. Das variable Antriebssystem kann einen variablen Antrieb beinhalten, der mit der variablen Eingangsantriebswelle gekoppelt ist, um zu ermöglichen, dass eine Übersetzung zwischen der Motorleistung und der Generatorantriebswelle einstellbar ist, wobei die variable Eingangsantriebswelle zu wenigstens einem/einer des Motorausgangs oder der Generatorantriebswelle versetzt ist. Das variable Antriebssystem kann eine Direktantriebskupplung beinhalten, um eine variable Leistungsübertragung durch den variablen Antrieb zu umgehen und eine direkte Leistungsübertragung ...

Pumpe mit einem elektrischen Antrieb

Die Erfindung betrifft Pumpe (12) mit einem elektrischen Antrieb (10) aufweisend ein Pumpengehäuse (20), welches eine Fluidkammer (21) mit zumindest einem Einlass (22) aufweist, welcher dafür eingerichtet ist, dass ein Hauptvolumenstrom (30) eines Fluides in einer Einströmrichtung (32) in die Fluidkammer (21) einströmt und mit zumindest einem Auslass (24) aufweist, welcher dafür eingerichtet ist, dass der Hauptvolumenstrom (30) des Fluides in einer Ausströmrichtung (34) aus der Fluidkammer (21) ausströmt und eine Drehachse (41) um welche ein vom elektrischen Antrieb (10) angetriebener Rotor (14) aufweisend eine Flügelradstruktur (16) rotiert, wobei der Rotor (14) in der Fluidkammer (21) angeordnet ist und wobei der Rotor (14) zumindest eine Fluidausgleichsöffnung (60) für einen Nebenvolumenstrom (62) des Fluides aufweist. Es wird vorgeschlagen, dass die Fluidausgleichsöffnung (60) eine Erstreckungsrichtung (64) aufweist, welche winklig zur Einströmrichtung (32) angeordnet ist.

Luftbalkenanordnung zum Trocknen von Tissue-Papier auf einem Band

Vorrichtung und Verfahren, die insbesondere zum Trocknen von Tissue-Papier geeignet sind. In bestimmten Ausführungsformen wird eine nasse Bahn, wie etwa eine Bahn, die aus einer Tissueherstellungsmaschine austritt, zu einem Luftschwebetrockner mit speziell angeordneten hierin beschriebenen Luftbalken und Anpralldüsen transportiert, wo die nasse Bahn getrocknet wird, während sie noch zumindest teilweise von einem luftdurchlässigen Band getragen wird. In bestimmten Ausführungsformen weist der speziell angeordnete Luftschwebetrockner eine oder mehrere Luftschwebetrocknereinheiten auf, durch die die nasse Bahn mit Hilfe einer tragenden Endlosschleife oder eines tragenden Endlosbandes von luftdurchlässiger Ausgestaltung transportiert wird. Die Luftbalken und gegenüberliegenden Anpralldüsen sind so angeordnet, dass sie die Bahn in einer wiederholten und abwechselnden Weise in Kontakt mit dem Band zwingen und dann anschließend die Bahn von der Bandoberfläche abheben, während die Bahn und das Band ...

System und Verfahren zum Aufnehmen von Nachbehandlungsblöcken

Ein Nachbehandlungssystem enthält ein Nachbehandlungsmodul mit einer Hülse (170), die sich zwischen einem ersten Ende (174) und einem zweiten Ende (176) erstreckt. Ein oder mehrere Nachbehandlungsblöcke (164) werden axial in eine Hülsenöffnung (178) eingesetzt, die in dem ersten Ende (174) der Hülse (170) angeordnet ist. Um zu verhindern, dass die Nachbehandlungsblöcke (164) unbeabsichtigt aus der Hülse (170) austreten, ist ein unverlierbarer Ring (210) als ein lose gepasster Kranz um das erste Ende (174) der Hülse (170) angeordnet. Der unverlierbare Ring (210) wird durch eine in Umfangsrichtung verlaufende Sicke (180), die um das erste Ende (174) vorsteht, an der Hülse (170) gehalten. Der unverlierbare Ring (210) kann mit einem benachbart zu dem ersten Ende (174) platzierten Haltering (230) verbunden werden. Bei einer Verbindung mit dem unverlierbaren Ring (210) erstreckt sich ein Teil des Halterings (230) teilweise über die Hülsenöffnung (178) und blockiert diese, so dass ein Austreten ...

SICHERER ROBOTERWERKZEUGWECHSLER

Bei einem inhärent sicheren Roboterwerkzeugwechsler wird eine Mastereinheit mit einer Werkzeugeinheit mittels einer ersten Energiequelle gekoppelt und von der Werkzeugeinheit unter Verwendung einer separaten, zweiten Energiequelle entkoppelt. Energie der zweiten Energiequelle ist nur verfügbar, wenn sich ein angebrachtes Werkzeug sicher in einem Werkzeuggestell befindet. Bei Ausführungsformen, bei welchen die erste Energiequelle nicht selektiv angelegt wird, wie z. B. bei einer konstanten Vorspannung, welche durch eine Feder bereitgestellt wird, hält ein Arretierungsmechanismus die Mastereinheit in einem entkoppelten Zustand, wenn die Mastereinheit von der Werkzeugeinheit entfernt wird. Der Arretierungsmechanismus ermöglicht der Mastereinheit, sich mit einer anderen Werkzeugeinheit zu koppeln, wenn sie physikalisch gegen die neue Werkzeugeinheit stößt.

REGELUNG FÜR EIN SIMULIERTES BOHRLOCH ZUM PRÜFEN MIT DYNAMISCHEM UNTERDRUCK

Um die Effizienz eines Perforierungswerkzeugsystems zu optimieren, können untertage herrschende Bedingungen simuliert werden, um die optimale Auslegung für das Perforierungswerkzeugsystem zu bestimmen. Ein simuliertes Bohrloch ist in einer simulierten Bohrlochummantelung angeordnet und an eine Formationsprobe gekoppelt. Das simulierte Bohrloch umfasst das Perforierungswerkzeugsystem und eine oder mehrere Füllscheiben, die ein Volumen des simulierten Bohrlochs aufbrauchen. Die Füllscheiben werden verwendet, um den dynamischen Unterdruck für eine jeweilige Simulation eines Perforierungswerkzeugsystems zu regeln. Eine oder mehrere Messungen, die mit dem Perforierungswerkzeugsystem verbunden sind, können zusammen mit einer oder mehreren Aufnahmen generiert werden, nachdem Sprengladungen des Perforierungswerkzeugsystems zum Detonieren gebracht worden sind. Das Perforierungswerkzeugsystem kann zumindest teilweise auf der Grundlage der einen oder mehreren Messungen und der einen oder mehreren ...

KATALYSIERTES FILTER ZUM BEHANDELN VON ABGAS

Beschrieben wird ein Dieselpartikelfilter mit der Fähigkeit, Ruß aus einem Abgas während eines Betreibens des Filters bei niedrigem Rückdruck zu entfernen, wobei das Filter a) ein Wandstromfiltersubstrat mit einer mittleren Porengröße, einer Einlassseite, einer Auslassseite und einem porösen Inneren zwischen der Einlassseite und der Auslassseite und b) eine von der Einlassseite des Substrats her aufgetragene Katalysatorzusammensetzung umfasst, wobei die Katalysatorzusammensetzung eine d50-Teilchengrößenverteilung aufweist, wobei die d50-Teilchengrößenverteilung kleiner als die mittlere Porengröße geteilt durch 4,9 ist und wobei die Auslassseite im Wesentlichen frei von einer Katalysatorbeschichtung ist.

PNEUMATISCHE SICHERHEITSVERRIEGELUNG

Ein Roboterwerkzeugwechsler stellt inhärent einen sicheren Entkopplungsvorgang sicher, indem ein Pneumatikfluid nur in dem Fall zu einem Entkopplungsanschluss eines pneumatischen Kopplungsmechanismus bereitgestellt wird, wenn der Werkzeugwechsler auf einem Werkzeuggestell platziert und geeignet mit diesem ausgerichtet ist. Ein Pneumatikfluid zum Entkoppeln des pneumatischen Kopplungsmechanismus wird von einer Luftquelle zu dem Werkzeuggestell geleitet. Ein Durchgang in dem Werkzeuggestell führt das Pneumatikfluid zu einem pneumatischen Pfad in dem Werkzeugwechsler, welcher zu einem Entkopplungsanschluss des pneumatischen Kopplungsmechanismus führt. Daher muss der Werkzeugwechsler auf dem Werkzeuggestell platziert sein, damit der Entkopplungsanschluss ein Pneumatikfluid aufnehmen kann. Darüber hinaus befindet sich eine Sicherheitskupplung auf dem pneumatischen Pfad zwischen dem Werkzeuggestell und dem Entkopplungsanschluss. Die Sicherheitskupplung erfordert, dass der Werkzeugwechsler für ...

Berührungsloses Messsystem mit einer auf einem mikroelektromechanischen System basierenden Lichtquelle

Ein berührungsloses Messsystem wird zur Verfügung gestellt, um dreidimensionale Profildaten eines Objektes zu erhalten. Das System umfasst ein Lichtquellensubsystem, welches ausgebildet ist, um einen Lichtpunkt in einer Beleuchtungsregion abzutasten; ein erstes Abbildungsgerät mit einem Bildfeld, das angeordnet ist, um sich mit der Beleuchtungsregion zu überschneiden und welches ausgebildet ist, um Bilddaten aufzunehmen; und ein zweiten Abbildungsgerät mit einem Bildfeld, was angeordnet ist, um sich mit der Beleuchtungsregion zu überschneiden und welches ausgebildet ist, um Bilddaten zu erhalten. Ein erstes Kontrollmodul steht in Datenverbindung mit dem ersten Abbildungsgerät, um Profilinformationen zu ermitteln für ein Objekt in dem Bildfeld des ersten Abbildungsgerätes und um die Profilinformation für das Objekt in einem allgemeinen Koordinatensystem anzuzeigen. Ein zweites Kontrollmodul steht in Datenverbindung mit dem zweiten Abbildungsgerät, um Profilinformationen des Objektes zu ermitteln ...

Anwenden dreiachsiger Spannungen auf eine Kernprobe während Perforations- und Fliesstests

Vorrichtungen und Verfahren zum Anwenden dreiachsiger Spannungen auf eine Kernprobe während Perforations- und Fließtests. Eine Gesteinskernprobe wird in einer Befestigungshülle einer Überlagerungsspannungsvorrichtung positioniert, die in einem Druckbehälter platziert ist. Der Druckbehälter wendet einen Behälterdruck auf die Überlagerungsspannungsvorrichtung an. Die Überlagerungsspannungsvorrichtung enthält eine Vielzahl von Spannungselementen, die entlang ihrer drei Hauptachsen Überlagerungsspannungen auf die Kernprobe anwenden. Den angewandten Überlagerungsspannungen wird durch eine Kombination der strukturellen Integrität der Überlagerungsspannungsvorrichtung und der auf die Überlagerungsspannungsvorrichtung angewandten Umfangsstütze durch den Behälterdruck widerstanden. Mit den angewandten Überlagerungsspannungen kann die Kernprobe Perforationstests, Produktionstests und Injektionstests unterzogen werden.

Treibmittelstimulation zur Messung der vorübergehenden Druckauswirkungen des Treibmittels

Die Simulation von vorübergehenden Druckauswirkungen in einem Bohrloch aufgrund einer Treibmittelstimulation einer Formation stellt Informationen bereit, die zur Auswahl einer Art eines Perforationswerkzeugsystems und anderer Komponenten verwendet werden können, die zur effektiven Stimulation einer Formation beitragen. Ein Bohrlochsimulatordruckbehälter umfasst ein Perforationswerkzeugsystem, das eine Art von Perforationspistolenanordnung umfasst, die eine oder mehrere Hohlladungen umfasst. Eine Treibmittelscheibenanordnung neben einer Probeformation ist mit dem Perforationswerkzeugsystem gekoppelt. Die Treibmittelscheibenanordnung umfasst eine oder mehrere Komponenten zum Befestigen des Treibmittels. Eine vorübergehende Druckauswirkung kann gemessen werden, sobald die eine oder die mehreren Hohlladungen detoniert sind und das Treibmittel gezündet oder deflagriert ist. Die gemessenen vorübergehenden Druckauswirkungen können verwendet werden, um eine oder mehrere Komponenten des Perforationswerkzeugsystems ...

Charge transport layers and films containing the same

The invention provides a film comprising at least two layers, Layer A and Layer B, and wherein Layer(A) is formed from a Composition A comprising at least one compound selected from Formula A: wherein Np is selected from 1-naphthyl or 2-naphthyl, and wherein each R is described herein; and wherein Layer B is formed from a Composition B comprising at least one “HTL compound;” and wherein Layer A is not adjacent to Layer B. The invention also provides a composition comprising at least one compound selected from Formula A: wherein each R is described herein, and wherein the compound has a Tg greater than, or equal to, 115° C.

Lacrosse stick pocket and related method of manufacture

A lacrosse head pocket includes an elongated single layer runner with multiple cross pieces. The single layer runner can be constructed from a material, such as a polymeric material, molded over the cross pieces. The cross pieces and/or runner can include speed lace loops with which a net lace can be joined. A related method includes providing cross pieces, overmolding a polymeric material over the cross pieces to form a single layer runner, where the overmolded material is the only structure extending between and connecting the cross pieces, and where the cross pieces are transverse to the runners. Another method includes providing a pocket base overmolding the base with a polymeric material to cover portions of it, and forming connection elements between different portions independently of any other components of the pocket base.

Multi-band infrared imaging using stacked colloidal quantum-dot photodiodes

Photodetectors based on colloidal quantum dots and methods of making the photodetectors are provided. Also provided are methods for doping films of colloidal quantum dots via a solid-state cation exchange method. The photodetectors include multi-band photodetectors composed of two or more rectifying photodiodes stacked in aback-to-back configuration. The doping methods rely on a solid-state cation exchange that employs sacrificial semiconductor nanoparticles as a dopant source for a film of colloidal quantum dots.

Batrachotoxin Analogues, Compositions, Uses, and Preparation Thereof

Compounds relating to batrachotoxin are provided, in particular analogues that modulate the activity of sodium channels. Also provided are pharmaceutical compositions comprising compounds of the invention and a pharmaceutically acceptable carrier, including vehicles that modulate transdermal permeation of the compound. The subject compounds are useful in treatments, including treatments to reduce neuronal activity or to bring about muscular relaxation. The compounds also find use in the treatment of subjects suffering from a voltage-gated sodium channel-enhanced ailment or from pain. Further methods are provided for the preparation of the batrachotoxin-related compounds.

High intensity modular light fixtures

The present disclosure describes advanced lighting elements, in particular solid-state lighting elements, and luminaires that include an array of lighting elements. The lighting elements, and luminaires including the lighting elements can exhibit benefits that include high optical efficiency and therefore high luminous efficacy; extraordinary directional control and therefore extraordinary glare control and efficacy of delivered lumens; and exceptional mixing of individual-device emission providing exceptional suppression of punch-through and color breakup. In many cases, the architecture can be amenable to low-cost manufacturing in a modular format.

Treatment of multiple sclerosis with a 1,2,4-triazolo [1,5a] pyridine derivative

The present disclosure provides methods and compositions for treating chronic autoimmune diseases, such as multiple sclerosis, using [8-(4-methanesulfonyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[3-(4-methyl-piperazin-1-yl)-phenyl]-amine or a pharmaceutically acceptable salt thereof.

Solid forms of fxr agonists

Disclosed herein are novel solid forms of FXR agonists. The disclosure also relates to pharmaceutical compositions containing one or more of the solid forms disclosed herein, as well as methods of using the solid forms in the treatment of conditions mediated by FXR. The disclosure also relates to methods for obtaining such solid forms.

Compositions and methods for prevention of escape mutation in the treatment of her2/neu over-expressing tumors

This invention provides compositions and methods for treating and vaccinating against a Her2/neu antigen-expressing tumor and inducing an immune response against dominant in a non-human animal.

Alpha-Hemolysin Variants and Uses Thereof

Described herein are variants of alpha-hemolysin having at least one mutation, such as a mutation to a positive charge. In certain examples, the mutation is selected from V149K, E287R, H35G, T109K, P151K, K147N, E111N, M113A, or combinations thereof in the mature, wild-type alpha-hemolysin amino acid sequence. The α-hemolysin variants may also include a substitution at H144A and/or a series of glycine residues spanning residues 127 to 131 of the mature, wild-type alpha hemolysin. Also provided are nanopore assemblies including the alpha-hemolysin variants, the assembly having a decreased time-to-thread. The decreased time-to-thread, for example, increases DNA sequencing efficiency and accuracy.

Systems and methods for interacting with overlapping regions of interest in machine vision applications

Example systems and methods for interacting with overlapping regions of interest (ROls) in machine vision applications are disclosed. An example system includes a machine vision camera, and a client computing device coupled to the machine vision camera. The client computing device configured to: receive an image from the machine vision camera; present the image on a canvas, wherein the canvas is part of a first user interface of a machine vision application displayed on the client computing device; present a first ROI associated with a first machine vision tool on the canvas; present a second ROI associated with a second machine vision tool on the canvas; and target the first ROI or the second ROI as a targeted ROI for interaction based upon distances from a pointer displayed on the canvas to features of the first ROI and the second ROI.

polymerization catalysts

Realizaciones de la presente divulgación dirigidas a catalizadores de polimerización que tienen un encadenamiento de etileno mejorado y/o una productividad de catalizador mejorada. Como ejemplo, la presente descripción proporciona un catalizador de polimerización de Fórmula (I), en el que cada uno de R1 a R12 es independientemente un grupo alquilo, arilo o aralquilo C1 a C20, o un hidrógeno, en el que al menos uno de R4 a R7 no es un hidrógeno, en el que M es un metal del Grupo 4, y en el que cada X es independientemente un haluro, alquilo C1 a C20, aralquilo o hidrógeno (Traducción automática con Google Translate, sin valor legal) Embodiments of the present disclosure directed to polymerization catalysts having improved ethylene chaining and/or improved catalyst productivity. As an example, the present disclosure provides a polymerization catalyst of Formula (I), wherein each of R1 to R12 is independently a C1 to C20 alkyl, aryl or aralkyl group, or a hydrogen, wherein at least one of R4 to R7 is not a hydrogen, where M is a Group 4 metal, and where each X is independently a halide, C1 to C20 alkyl, aralkyl, or hydrogen.

Electrolytic process and product

Electroluminescent and light reflective helmet

An illuminated safety helmet incorporating a light panel that is capable of producing electroluminescence, and also, reflecting incident light that is independent of the electroluminescence function of the panel. The light panel is secured to the helmet so as to be visible to an observer, and a power source is secured to the helmet so as not to interfere with the wearing of the helmet. The power source is connected to the light panel, and a control switch may be provided to control the power directed from the power source to the light panel.

Condensate glucose analyzer

The present invention provides systems and methods for analyzing glucose present in exhaled breath condensate (EBC). In certain embodiments of the invention, electrochemical- or coulometric-based sensing technologies are used to analyze EBC for the presence and/or concentration of glucose.

Circuit and apparatus for decoupling rf surface coils

A decoupling circuit for a radio frequency (RF) surface coil having a plurality of tuning capacitors includes at least two decoupling points and a DC source coupled to the at least two decoupling points. Each decoupling point is associated with one of the plurality of tuning capacitors. Each decoupling point includes a decoupling inductor connected in parallel with a tuning capacitor, a diode connected in series with the decoupling inductor and in parallel with the tuning capacitor, a resistor connected in parallel with the diode and at least one isolating inductor connected between the resistor and the diode to RF isolate the resistor. The value of the resistor in each decoupling point is selected to maintain a high quality factor (Q) of the RF surface coil and to reduce the switching speed of the decoupling circuit.

IRAK degraders and uses thereof

The present invention provides compounds, compositions thereof, and methods of using the same.

IRAK degraders and uses thereof

The present invention provides compounds, compositions thereof, and methods of using the same.

Tricyclic CRBN ligands and uses thereof

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of CRBN, and the treatment of CRBN-mediated disorders.

CRBN ligands and uses thereof

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of CRBN, and the treatment of CRBN-mediated disorders.

IRAK degraders and uses thereof

The present invention provides compounds, compositions thereof, and methods of using the same.

IRAK degraders and uses thereof

The present invention provides compounds, compositions thereof, and methods of using the same.

N-benzyl-3,4-dihydroxypyridine-2-carboxamide and n-benzyl-2,3-dihydroxypyridine-4-carboxamide compounds useful as hiv integras inhibitors

N-Benzyl-dihydroxypyridine carboxamide compounds are inhibitors of HIV integrase and inhibitors of HIV replication. In one embodiment, the dihydroxypyridine carboxamides are of Formula (I) wherein Q is Formula (II) or Formula (III); T is Formula (IV); and R1, R2, X1,X2,X3, and Y1 are defined herein. The compounds are useful in the prevention and treatment of infection by HIV and in the prevention, delay in the onset, and treatment of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.

Holder for an endotracheal tube

The invention is concerned with an endotracheal tube holder formed of a generally rigid flat bar having a lateral cut-out leaving a reduced flexible neck connecting the remaining bar portions together for relative swinging about an axis through the neck generally perpendicular to the bar, the cut being configured to conformably receive and circumferentially clamp about a received tube, and one side edge of the bar being provided on respective bar portions with a releasably interengageable catch and a latch which automatically snap into interengagement upon relative swinging movement of the bar portions, all without adversely displacing the tube.

System for detecting and accommodating gas turbine engine fan damage

Foreign object ingestion damage detection and accommodation system for a gas turbine engine system having a gas turbine engine with multiple rotating members, such as a twin spool configuration. System includes speed sensors for sensing the rotational speed of at least two rotating members. Sensors are coupled to a controller which detects damage by comparing the sensed speed of the second rotational member to an expected speed. Expected speed is determined from the sensed speed of the first rotating member using a known characteristic relationship between the the first and second rotating member speeds for the given gas turbine engine design. Thrust loss accommodation is triggered when damage is detected. Accommodation mode provides a synthesized primary thrust control feedback signal in lieu of the sensed signal for a damaged rotational member. Synthesized signal is derived from the sensed speed for the undamaged rotational member.

N-benzyl-3,4-dihyroxypyridine-2-carboxamide and n-benzyl-2,3-dihydroxypyridine-4-carboxamide compounds useful as hiv integrase inhibitors

Protective glove having contoured wrist guard

A protective sports glove including a contoured wrist cuff that substantially shields a gap defined between adjacent portions of the protective sports glove, such as hand and cuff portions. The contoured wrist cuff can include a leading edge that contours forwardly adjacent a thumb portion of the contoured wrist cuff and rearwardly across a portion of the radial side of a wearer's hand when the glove is on the wearer's hand. This can allow protection of the wearer's wrist in flexion without also impairing movement of the wearer's wrist.

Method for preparing an n- (aliphatic or aromatic)carbonyl -2-aminoacetamide compound and a cyclyzed compound

The present invention relates to a method for preparing an N-[(aliphatic or aromatic)carbonyl]-2-aminoacetamide compound of formula (I) wherein Ra is (II); Raa is hydrogen, optionally substituted aliphatic or optionally substituted aromatic; Rb is hydrogen, optionally substituted aliphatic or optionally substituted aromatic; Rca and Rcb are independently hydrogen, optionally substituted aliphatic or optionally substituted aromatic; Rd is (III); and Rda is optionally substituted aliphatic or optionally substituted aromatic; and Raa is substituted with a primary or secondary protected amine that upon deprotection can react with the *ab or *db carbon, or at least one of Rb, Rca or Rcb where each is at least substituted with an activated carboxylic acid to form a 5-7 membered cyclic ring; or Rb is substituted with a primary or secondary protected amine that upon deprotection can react with the *ab or *db carbon, or at least one of Raa, Rca or Rcb where each is at least substituted with an activated carboxylic acid to form a 5-7 membered cyclic ring; or Rca and Rcb are independently substituted with a primary or secondary protected amine that upon deprotection can react with the *ab or *db carbon, or at least one of Raa, Rb, Rca, Rcb or Rda where each is at least substituted with an activated carboxylic acid to form a 5-7 membered cyclic ring; or Rda is substituted with a primary or secondary protected amine that upon deprotection can react with at least one of Rca or Rcb where each is at least substituted with an activated carboxylic acid to form a 5-7 membered cyclic ring, provided that when Raa is substituted with a primary or secondary protected amine that upon deprotection can react with Rb at least substituted with an activated carboxylic acid, then Raa is other than substituted aliphatic, comprising reacting the following four compounds: a carbonyl compound of formula (IV), an amine compound of formula NH2Rb, an isonitrile compound of formula NCRda, and an acid ...

Hot melt sealants, adhesives andthe like

Irak degraders and uses thereof

The present invention provides compounds, compositions thereof, and methods of using the same.

Solid forms of fxr agonists

Disclosed herein are novel solid forms of FXR agonist of Formula (I). The disclosure also relates to pharmaceutical compositions containing one or more of the solid forms disclosed herein, as well as methods of using the solid forms in the treatment of conditions mediated by FXR. The disclosure also relates to methods for obtaining such solid forms.

Methods of treating cancer using tnfrsf25 antibodies

The present disclosure is directed to a method of treating cancer using a TNFRSF25 agonistic antibody or antigen binding fragment thereof and their combinations with additional therapies such as cancer vaccines and/or checkpoint inhibitors.

Inventory control and communication system

An inventory control (24) and communication system provides automated real-time polling of stock levels and ordering to allow stock levels to be maintained. A bin (12) is established for each stock item. Transducers (14) are associated with each storage unit to produce a signal (18) indicative of the weight of the stock items. The signals are transmitted at regular intervals to a central inventory server, which maintains information about transducer location and the corresponding stock item. Inventory logic in the central inventory server computes the quantity of each stock item from the transducer signals and the weight of the stock items. Iventory logic also includes threshold values for the minimum and maximum quantity of each stock item. When the quantity of a stock item reaches a minimum threshold, inventory logic sends and order to the supplier to restore the stock item to the maximum quantity threshold.

Irak degraders and uses thereof

The present invention provides compounds, compositions thereof, and methods of using the same.

Substituted (aryl, heteroaryl, arylmethyl or heteroarylmethyl) hydroxamic acid compounds

This invention is directed to compounds of formula (I), wherein the variables are as described herein. Compounds within the scope of the present invention possess useful properties, more particularly pharmaceutical properties. They are especially useful for inhibiting the production or physiological effects of TNF in the treatment of a patient suffering from a disease state associated with a physiologically detrimental excess of tumor necrosis factor (TNF). Compounds within the scope of the present invention also inhibit cyclic AMP phosphodiesterase, and are useful in treating a disease state associated with pathological conditions that are modulated by inhibiting cyclic AMP phosphodiesterase, such disease states including inflammatory and autoimmune diseases, in particular type IV cyclic AMP phosphodiesterase. Compounds within the scope of the present invention may also inhibit an MMP, and are useful in treating a disease state associated with pathological conditions that are modulated by inhibiting MMPs, such disease states involve tissue breakdown and those associated with a physiologically detrimental excess of TNF. The present invention is therefore also directed to the pharmaceutical use of the compounds, pharmaceutical compositions containing the compounds, intermediates leading thereto and methods for the preparation of the compounds and their intermediates.

Substituted (aryl, heteroaryl, arylmethyl or heteroarylmethyl) hydroxamic acid compounds

This invention is directed to compounds of formula (I), wherein the variables are as described herein. Compounds within the scope of the present invention possess useful properties, more particularly pharmaceutical properties. They are especially useful for inhibiting the production or physiological effects of TNF in the treatment of a patient suffering from a disease state associated with a physiologically detrimental excess of tumor necrosis factor (TNF). Compounds within the scope of the present invention also inhibit cyclic AMP phosphodiesterase, and are useful in treating a disease state associated with pathological conditions that are modulated by inhibiting cyclic AMP phosphodiesterase, such disease states including inflammatory and autoimmune diseases, in particular type IV cyclic AMP phosphodiesterase. Compounds within the scope of the present invention may also inhibit an MMP, and are useful in treating a disease state associated with pathological conditions that are modulated by inhibiting MMPs, such disease states involve tissue breakdown and those associated with a physiologically detrimental excess of TNF. The present invention is therefore also directed to the pharmaceutical use of the compounds, pharmaceutical compositions containing the compounds, intermediates leading thereto and methods for the preparation of the compounds and their intermediates.

Polymers, photoresist compositions and methods of forming photolithographic patterns

Polymers containing a unit having a particular acetal moiety and photoresist compositions containing such a polymer. Substrates coated with the photoresist compositions and methods of forming photolithographic patterns. The polymers, photoresist compositions, methods and coated substrates find particular applicability in the manufacture of semiconductor devices.

Portable communication device

Putting-out machine

Heteroaryl sodium channel inhibitors

The present invention provides compounds of Formula I or II, or pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav 1.7. The compounds are useful for the treatment of diseases treatable by inhibition of channels such as pain disorders. Also provided are pharmaceutical compositions containing compounds of the present invention.

Torque-angle wrench

A torque-angle wrench (100) is pro-vided with a handle (104) for applying torque, such as to a fastener or bolt, through a tightening angle, at a rotational angular velocity. A piezoelectric gyro-scopic sensor device (102) including cir-cuitry for vibrating an oscillating body is coupled to the wrench. As the wrench is rotated through the tightening angle, its rotational angular velocity causes the vi-brating body to alter its direction of vibra-tion. The new vibrating pattern is sensed and converted, by appropriate sensing cir-cuitry, into an electrical signal proportional in intensity to the rotational angular veloc-ity of the wrench. The electrical signal can be electronically processed by appropriate conversion and display circuitry to provide a visual indication of the tightening angle. Such conversion and display circuitry can be integral with the wrench or as part of an adaptably coupled meter non-integrally connected to the sensor device.

Toroidal low-field reactive gas and plasma source having a dielectric vacuum vessel

System for rebuilding dispersed data

A digital data file storage system is disclosed in which original data files to be stored are dispersed using some form of information dispersal algorithm into a number of file “slices” or subsets in such a manner that the data in each file share is less usable or less recognizable or completely unusable or completely unrecognizable by itself except when combined with some or all of the other file shares. These file shares are stored on separate digital data storage devices as a way of increasing privacy and security. As dispersed file shares are being transferred to or stored on a grid of distributed storage locations, various grid resources may become non-operational or may operate below at a less than optimal level. When dispersed file shares are being written to a dispersed storage grid which not available, the grid clients designates the dispersed data shares that could not be written at that time on a Rebuild List. In addition when grid resources already storing dispersed data become non-available, a process within the dispersed storage grid designates the dispersed data shares that need to be recreated on the Rebuild List. At other points in time a separate process reads the set of Rebuild Lists used to create the corresponding dispersed data and stores that data on available grid resources.

Lacrosse stick pocket and related method of manufacture

A lacrosse head pocket includes an elongated single layer runner with multiple cross pieces. The single layer runner can be constructed from a material, such as a polymeric material, molded over the cross pieces. The cross pieces and/or runner can include speed lace loops with which a net lace can be joined. A related method includes providing cross pieces, overmolding a polymeric material over the cross pieces to form a single layer runner, where the overmolded material is the only structure extending between and connecting the cross pieces, and where the cross pieces are transverse to the runners. Another method includes providing a pocket base overmolding the base with a polymeric material to cover portions of it, and forming connection elements between different portions independently of any other components of the pocket base.

Irak degraders and uses thereof

The present invention provides compounds, compositions thereof, and methods of using the same.

Condensate glucose analyzer

Systems and methods for analyzing glucose present in exhaled breath condensate (EBC). In certain embodiments, electrochemical- or coulometnc-based sensing technologies are used to analyze EBC for the presence and/or concentration of glucose. Based on the detected glucose m EBC, the subject invention provides systems and methods for non-mvasive, accurate assessment of blood glucose levels.

Polymer composition, photoresist comprising the polymer composition, and coated article comprising the photoresist

A copolymer comprises the polymerized product of a dissolution-rate controlling monomer having the formula (I), an acyclic vinyl ether monomer of the formula (II), and a cyclic vinyl ether monomer of the formula (III): wherein R a , R b , R c , L, X, and Z 1 are defined herein. A photoresist composition comprising the copolymer is described, as is an article coated with the photoresist composition, and a method of forming an electronic device using the photoresist composition.

HIV integrase inhibitors

Circuit and apparatus for decoupling RF surface coils

A decoupling circuit for a radio frequency (RF) surface coil having a plurality of tuning capacitors includes at least two decoupling points and a DC source coupled to the at least two decoupling points. Each decoupling point is associated with one of the plurality of tuning capacitors. Each decoupling point includes a decoupling inductor connected in parallel with a tuning capacitor, a diode connected in series with the decoupling inductor and in parallel with the tuning capacitor, a resistor connected in parallel with the diode and at least one isolating inductor connected between the resistor and the diode to RF isolate the resistor. The value of the resistor in each decoupling point is selected to maintain a high quality factor (Q) of the RF surface coil and to reduce the switching speed of the decoupling circuit.

Portable jump-starting battery pack with charge monitoring system

A battery pack (10) includes a lead-acid battery (11) and a charger port (12) and an electronic switch (14) connected between the two, the switch (14) being controlled by a microcontroller (15) which is connected to each of the battery (11) and the charger port (12) for separately monitoring the voltages thereat. The microcontroller (15) operates under the control of a program which includes routines for comparing the battery voltage to the charger port voltage, for preventing closure of the switch (14) unless the charger port voltage is at least a predetermined level and at least the battery voltage, for adjusting the duty cycle of the switch in accordance with the magnitude of the difference between the charger port voltage and the battery voltage, for detecting a bad battery by measuring the length of time required to increase the battery voltage from first to second predetermined levels, for reducing the switch duty cycle to a trickle charge level in the event of bad battery detection, and for disabling the bad battery detection routine in the event that a cigarette lighter adapter is coupled to the charger port. Audible and visible indicators may be provided to signal charging condition.

Protein degraders and uses thereof

Lacrosse stick pocket and related method of manufacture

A lacrosse head pocket includes an elongated single layer runner with multiple cross pieces. The single layer runner can be constructed from a material, such as a polymeric material, molded over the cross pieces. The cross pieces and/or runner can include speed lace loops with which a net lace can be joined. A related method includes providing cross pieces, overmolding a polymeric material over the cross pieces to form a single layer runner, where the overmolded material is the only structure extending between and connecting the cross pieces, and where the cross pieces are transverse to the runners. Another method includes providing a pocket base overmolding the base with a polymeric material to cover portions of it, and forming connection elements between different portions independently of any other components of the pocket base.

Inductively-driven plasma light source

An apparatus for producing light includes a chamber (104) that has a plasma discharge region (112) and that contains an ionizable medium. The apparatus also includes a magnetic core (108) that surrounds a portion of the plasma discharge region (112). The apparatus also includes a pulse power system (136) for providing at least one pulse of energy to the magnetic core (108) for delivering power to a plasma formed in the plasma discharge region (112). The plasma has a localized high intensity zone (144).

Mdm2 degraders and uses thereof

The present invention relates to compounds and methods useful for the modulation of mouse double minute 2 homolog ("MDM2") protein via ubiquitination and/or degradation by compounds according to the present invention.

Methods of treating cancer using tnfrsf25 antibodies

The present disclosure is directed to a method of treating cancer using a TNFRSF25 agonistic antibody or antigen binding fragment thereof and their combinations with additional therapies such as cancer vaccines and/or checkpoint inhibitors.

Process for the manufacture of incandescent-lamp bases.

Toroidal low-field reactive gas and plasma source having a dielectric vacuum vessel

Plasma ignition and cooling apparatus and methods for plasma systems are described. An apparatus can include a vessel and at least one ignition electrode adjacent to the vessel. A total length of a dimension of the at least one ignition electrode is greater than 10% of a length of the vessel's channel. The apparatus can include a dielectric toroidal vessel, a heat sink having multiple segments urged toward the vessel by a spring-loaded mechanism, and a thermal interface between the vessel and the heat sink. A method can include providing a gas having a flow rate and a pressure and directing a portion of the flow rate of the gas into a vessel channel. The gas is ignited in the channel while the remaining portion of the flow rate is directed away from the channel.

Tool box locking mechanisms for remote activation

An improved method of rotating the lockrod of a tool storage unit to the "locked" or "unlocked" position by use of a linear actuator to rotate the lockrod actuator, where the linear actuator operates electrically, allowing for control by any remotely or automatically operated system. The tool storage unit locking mechanisms include a center-neutral key position that rotates 90 degrees in either direction from center to lock and unlock the unit. This design allows a standard key to operate the locking mechanism, but also allows a secondary mechanism (such as an electromagnetically driven mechanism) to directly operate the lock. Due to its specifics, the design would also allow for retrofitability.

Point-of-care diagnostic systems and containers for same

The present disclosure relates to a medical diagnostic system. In various embodiments, the system includes a housing, a first receptacle in the housing for receiving a reagent container, a second receptacle in the housing for receiving a working fluid and waste container, where the second receptacle is larger than the first receptacle, two reagent access needles positioned and fixed within the first receptacle with each of the two reagent access needles being positioned to access the reagent container, and a working fluid access needle and a waste access needle positioned and fixed within the second receptacle with the working fluid access needle and the waste access needle being positioned to access the working fluid and waste container.

Drug adherence monitoring system

The present invention provides novel methods for monitoring subject adherence in taking prescribed drugs by detecting markers in exhaled breath after a subject takes the prescribed drug. In particular, the present invention provides novel methods for making additives that are combined with the drug(s). Upon biological breakdown of the drug/additive formulation in a subject's body, markers resulting directly from the biological breakdown of the additives are detected in exhaled breath using sensor technology. In certain embodiments of the invention, the drug adherence monitoring systems and methods include a reporting system capable of tracking subject compliance (either remotely or proximately) and of providing necessary alerts to the subject, caregiver, healthcare provider, and the like.

Accelerometer-based apparatus and method for determining engine power balance

An accelerometer-based probe is magnetically mountable on an internal combustion engine and is coupled to an associated engine analyzer having a CRT display. The probe includes an accelerometer sensor having an axis of sensitivity and is mounted on the engine in a sensing position such that the axis of sensitivity is disposed substantially in a plane perpendicular to the axis of rotation of the engine crankshaft and is directed in the direction of rotation of the crankshaft. The sensor generates a waveform signal indicative of the engine vibrations sensed and includes circuitry for selectively amplifying the waveform signal for display on the CRT screen. The waveform signal thus generated provides an indication of relative power contribution by each cylinder of the engine for a power balance determination.

Board mountable electrical connector

Internal hydroforming method for manufacturing heat pipe wicks utilizing a hollow mandrel and sheath

A forming assembly for forming a wick is disclosed. The forming assembly includes a tube inflatable to an inflated configuration. A wick mesh is configured to be wrapped about the tube. The forming assembly further includes a sheath positionable about the tube and the wick mesh. The tube and the sheath are configured to compress the wick mesh and form the wick based on the tube inflating towards the inflated configuration.

Tnfrsf25-mediated treatments of immune diseases and disorders

The present disclosure is directed to a method of treating or preventing diabetes, prediabetes, and/or glucose intolerance using TNF Receptor Superfamily Member 25 (TNFRSF25) agonistic antibody or antigen binding fragment thereof. The disclosure is also directed to methods for increasing graft survival and for treating or preventing graft-versus-host disease (GVHD) using TNFRSF25 agonistic antibody.

Photoconductive device

A semiconductor structure includes a GaAs or InP substrate, an In x Ga 1-x As epitaxial layer grown on the substrate, where x is greater than about 0.01 and less than about 0.53, and a wider bandgap epitaxial layer grown as a cap layer on top of the In x Ga 1-x As epitaxial layer.

Energy absorption member

Battery pack and over-voltage alarm therefor

A battery pack (10) has a pair of input/output terminals (18, 19) adapted to be connected across a source of charging voltage, and a lead-acid battery connected across the input/output terminals (18, 19). A Zener diode (22) is connected in series with a resistance (23 - 25) across the input/output terminals (18, 19), the resistance (23 - 25) forming part of a trigger circuit for triggering an alarm signal (20) to actuate a visible (16) and/or audible (17) annunciator when the charging voltage exceeds a threshold level. In one embodiment the trigger circuit is an IC comparator (21) having one input connected to a reference voltage drive from a voltage divider connected across the input/output terminals (18, 19), and the other input connected to the trigger circuit includes a pair of transistors (31, 37), one being turned ON by the trigger voltage and in turn ON the second transistor to produce the output signal and provide a feedback to latch on the first transistor.

Tool box locking mechanisms for remote activation

An improved method of rotating the lockrod of a tool storage unit to the "locked" or "unlocked" position by use of a linear actuator to rotate the lockrod actuator, where the linear actuator operates electrically, allowing for control by any remotely or automatically operated system. The tool storage unit locking mechanisms include a center-neutral key position that rotates 90 degrees in either direction from center to lock and unlock the unit. This design allows a standard key to operate the locking mechanism, but also allows a secondary mechanism (such as an electromagnetically driven mechanism) to directly operate the lock. Due to its specifics, the design would also allow for retrofitability.

Catcher's leg guard

Telephone handset

Electroluminescent sign

Signs including electroluminescent lamps are described. In accordance with one embodiment of the present invention, electroluminescent lamps are coupled to a sign by first forming a rear electrode on a front surface of the sign. After forming the rear electrode on the sign, a phosphor layer is screen printed over the rear electrode. A conductor layer is then screen printed to the phosphor layer to form an EL lamp.

Method for preparing an N-((aliphatic or aromatic)carbonyl)-2-aminoacetamide compound and a cyclyzed compound

Irak degraders and their uses

DEGRADADORES DE IRAK E USOS DOS MESMOS. A presente invenção refere-se a compostos, composições dos mesmos e métodos de uso dos mesmos.

Method for the identification of inhibitors of ornithine carbamoyltransferase, ketol-acid reductoisomerase, and fungal pathogenicity-conferring gene as antibiotics

The present inventors have discovered that ornithine carbamoyltransferase, ketol-acid reductoisomerase and a pathogenicity-conferring gene sequence (PCGI) are essential for normal fungal pathogenicity. Specifically, the inhibition of ornithine carbamoyltransferase gene expression in fungi eliminates pathogenicity, the inhibition of ketol-acid reductoisomerase gene expression in fungi results in drastically reduced pathogenicity, and the inhibition of the expression of the genomic sequence set forth in SEQ ID NO: 11 (PCGI) in fungi results in the elimination of pathogenicity. Thus, ornithine carbamoyltransferase, ketol-acid reductoisomerase, and PCGI are useful as targets for the identification of antibiotics, preferably antifungals. Accordingly, the present invention provides methods for the identification of compounds that inhibit ornithine carbamoyltransferase, ketol-acid reductoisomerase, and PCGI expression or activity. The methods of the invention are useful for the identification of antibiotics, preferably antifungals.

Irak degraders and uses thereof

The present invention provides compounds, compositions thereof, and methods of using the same.

Moca gateway splitter

A CATV/MoCA signal distribution system includes a first 2-way hybrid splitter for receiving a CATV input signal and splitting it into first and second CATV output signals, a second 2-way hybrid splitter for receiving the second CAN output signal and splitting it into third and fourth CAN output signals, with the latter being connected to a CATV output port. A first diplex filter is receptive of the first CAN output signal, and MoCA signals for providing electrical isolation therebetween and connecting them to a modem port. A second diplex filter is receptive of the third CATV output signal and MoCA signals for providing electrical isolation therebetween and connecting them to a Gateway port. A resistive splitter is connected between the first and second diplex filters and a plurality of individual MoCA signal ports for providing bidirectional MoCA signal flow therebetween.

Toroidal low-field reactive gas and plasma source having a dielectric vacuum vessel

Plasma ignition and cooling apparatus and methods for plasma systems are described. An apparatus can include a vessel and at least one ignition electrode adjacent to the vessel. A total length of a dimension of the at least one ignition electrode is greater than 10% of a length of the vessel's channel. The apparatus can include a dielectric toroidal vessel, a heat sink having multiple segments urged toward the vessel by a spring-loaded mechanism, and a thermal interface between the vessel and the heat sink. A method can include providing a gas having a flow rate and a pressure and directing a portion of the flow rate of the gas into a vessel channel. The gas is ignited in the channel while the remaining portion of the flow rate is directed away from the channel.

Machine for use in treating hides, skins, leather, and other similar pieces of work

Lacrosse head

Porous valve assembly

A valve assembly for controlling the flow of a predetermined fluid, including a tube having an open end forming an outlet port, and wherein the tube is made of a material that is porous with respect to the predetermined fluid, an outer wall forming a fluid chamber coaxially surrounding the porous tube and including an inlet port, and a valve member made of non-porous material received for sliding movement within the porous tube. Sliding movement of the valve member within the tube and towards the open end of the tube reduces the flow of the predetermined fluid from the fluid chamber, through the porous tube and through the outlet of the valve assembly, while sliding movement of the valve member within the tube and away from the open end of the tube increases the flow of the predetermined fluid from the fluid chamber, through the porous tube and through the outlet of the valve assembly.

Portable jump-starting battery pack with charge monitoring system

A battery pack (10) includes a lead-acid battery (11) and a charger port (12) and an electronic switch (14) connected between the two, the switch (14) being controlled by a microcontroller (15) which is connected to each of the battery (11) and the charger port (12) for separately monitoring the voltages thereat. The microcontroller (15) operates under the control of a program which includes routines for comparing the battery voltage to the charger port voltage, for preventing closure of the switch (14) unless the charger port voltage is at least a predetermined level and at least the battery voltage, for adjusting the duty cycle of the switch in accordance with the magnitude of the difference between the charger port voltage and the battery voltage, for detecting a bad battery by measuring the length of time required to increase the battery voltage from first to second predetermined levels, for reducing the switch duty cycle to a trickle charge level in the event of bad battery detection, and for disabling the bad battery detection routine in the event that a cigarette lighter adapter is coupled to the charger port. Audible and visible indicators may be provided to signal charging condition.

Torque-angle instrument

An electronic torque-angle instrument including a generally tubular body having a gripping section and a pivoting head for engaging a workpiece, such as a nut or bolt, and a housing associated with the body and containing electronics, including a microprocessor, which permit individual or simultaneous measurement of torque and angle applied to the workpiece. The microprocessor includes stored programs which interpret a signal from an input, such as a gyroscopic sensor, and sends the interpreted signal to an output means. The signal is finally displayed as an accurate torque measure and/or angle measure from the output means.

Electrolytic apparatus and method

Thrombin inhibitors

Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions having the structure (I) or a pharmaceutically acceptable salt thereof, wherein b is NY1 or O; c is CY2 or N; d is CY3 or N; e is CY4 or N; f is CY5 or N; g is CY6 or N; Y?4, Y5, and Y6¿ are independently hydrogen, C¿1-4? alkyl, or halogen; Y?1 and Y2¿ are independently hydrogen, C¿1-4? alkyl, C3-7 cycloalkyl, halogen, NH2, OH or C1-4 alkoxy, and Y?3¿ is hydrogen, C¿1-4? alkyl, C3-7 cycloalkyl, halogen, -CN, NH2, OH or C1-4 alkoxy; A is (II), (III), (IV), (V) or (VI); and W, W?1, R1, R3, R4, R5¿, X and Z are defined in the specification.

Irak degraders and uses thereof

The present invention provides compounds, compositions thereof, and methods of using the same.

Hiv integrase inhibitors

Hydroxy (tetra- or hexa-)hydronaphthyridine dione compounds of Formula I are inhibitors of HIV integrase and inhibitors of HIV replication: (I) wherein a, R1, R2, R3, R4 and R5 are defined herein. The compounds are useful in the prevention and treatment of infection by HIV and in the prevention, delay in the onset, and treatment of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.

Electrolytic apparatus and method

Solid forms of fxr agonists

Disclosed herein are novel solid forms of FXR agonist of Formula (I). The disclosure also relates to pharmaceutical compositions containing one or more of the solid forms disclosed herein, as well as methods of using the solid forms in the treatment of conditions mediated by FXR. The disclosure also relates to methods for obtaining such solid forms.

Irak degraders and uses thereof

The present invention provides compounds, compositions thereof, and methods of using the same.

Laser-heated infrared source

Described are infrared light sources and methods for generating infrared radiation. The infrared light source includes a source of laser radiation, a target and an enclosure. The target is positioned in a path of an output region of the source of laser radiation. The target includes an absorbing material that absorbs radiation at a wavelength within the lasing spectrum of the source of laser radiation and converts the absorbed radiation into thermal energy. The enclosure defines a cavity that includes the target. The enclosure includes an infrared reflecting film on a side that defines the cavity.

Condensate glucose analyzer

Systems and methods for analyzing glucose present in exhaled breath condensate (EBC). In certain embodiments, electrochemical- or coulometnc-based sensing technologies are used to analyze EBC for the presence and/or concentration of glucose. Based on the detected glucose m EBC, the subject invention provides systems and methods for non-mvasive, accurate assessment of blood glucose levels.

Inductively-driven plasma light source with magnetic core

An apparatus for producing light includes a chamber that has a plasma discharge region and that contains an ionizable medium. The apparatus also includes a magnetic core that surrounds a portion of the plasma discharge region. The apparatus also includes a pulse power system for providing at least one pulse of energy to the magnetic core for delivering power to a plasma formed in the plasma discharge region that forms a secondary circuit of a transformer. The plasma has a localized high intensity zone.

Proteasome inhibitor delanzomib for use in the treatment of lupus

The present invention provides a method for treating lupus in a subject, comprising the step of administering to the subject Compound A.

MEDICAL DIAGNOSTIC SYSTEM, AND, CONTAINER FOR A MEDICAL DIAGNOSTIC SYSTEM.

a presente descrição se refere a um sistema de diagnóstico médico. em várias modalidades, o sistema inclui um alojamento, um primeiro receptáculo no alojamento para receber um recipiente de reagente, um segundo receptáculo no alojamento para receber um fluido de trabalho e recipiente de resíduo, no qual o segundo receptáculo é maior do que o primeiro receptáculo, duas agulhas de acesso a reagentes posicionadas e fixadas dentro do primeiro receptáculo com cada uma das duas agulhas de acesso a reagentes sendo posicionadas para acessar o recipiente de reagente e uma agulha de acesso ao fluido de trabalho e uma agulha de acesso ao resíduo posicionadas e fixadas dentro do segundo receptáculo com a agulha de acesso ao fluido de trabalho e a agulha de acesso ao resíduo sendo posicionadas para acessar o fluido de trabalho e recipiente de resíduo. the present description refers to a medical diagnostic system. in various embodiments, the system includes a housing, a first receptacle in the housing to receive a reagent container, a second receptacle in the housing to receive a working fluid and waste container, in which the second receptacle is larger than the first receptacle , two reagent access needles positioned and fixed inside the first receptacle with each of the two reagent access needles being positioned to access the reagent container and a working fluid access needle and a waste access needle positioned and fixed inside the second receptacle with the needle for access to the working fluid and the needle for access to the waste being positioned to access the working fluid and waste container.

Art of tanning hides and skins

Irak degraders and uses thereof

The present invention provides compounds, compositions thereof, and methods of using the same.

Battery pack and over-voltage alarm therefor

A battery pack (10) has a pair of input/output terminals (18, 19) adapted to be connected across a source of charging voltage, and a lead-acid battery connected across the input/output terminals (18, 19). A Zener diode (22) is connected in series with a resistance (23 - 25) across the input/output terminals (18, 19), the resistance (23 - 25) forming part of a trigger circuit for triggering an alarm signal (20) to actuate a visible (16) and/or audible (17) annunciator when the charging voltage exceeds a threshold level. In one embodiment the trigger circuit is an IC comparator (21) having one input connected to a reference voltage drive from a voltage divider connected across the input/output terminals (18, 19), and the other input connected to the trigger circuit includes a pair of transistors (31, 37), one being turned ON by the trigger voltage and in turn ON the second transistor to produce the output signal and provide a feedback to latch on the first transistor.

Thrombin inhibitors

Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions having the following structure: or a pharmaceutically acceptable salt thereof, wherein b is NY or O; c is CY 2 or N; d is CY 3 or N; e is CY 4 or N; f is CY 5 or N; g is CY 6 or N; Y 4 , Y 5 , and Y 6 are independently hydrogen, C 1-4 alkyl, or halogen; Y 1 and Y 2 are independently hydrogen, C 1-4 alkyl, C 3-7 cycloalkyl, halogen, NH 2 , OH or C 1-4 alkoxy, and Y 3 is hydrogen, C 1-4 alkyl, C 3-7 cycloalkyl, halogen, —CN, NH 2 , OH or C 1-4 alkoxy; A is and W, W 1 , R 1 , R 3 , R 4 , R 5 , X and Z are defined in the specification.

Method and apparatus for implementing refresh in a synchronous dram system

A synchronous DRAM system with internal refresh is controlled by a refresh signal issued by an oscillator or memory controller coupled to the DRAM. By locating the oscillator on the processor or memory controller better control of the frequency of refresh is achieved, particularly, as the signal can be derived from a crystal which is not sensitive to variations in operating conditions. The oscillator drives a refresh signal on a bus or signal line to the DRAM, such that the refresh address counter is incremented and the row identified by the refresh address counter is refreshed.

Irak degraders and uses thereof

The present invention provides compounds, compositions thereof, and methods of using the same.

Galvanoplastic process and product.