Conjugues macromoleculaires d'hemoglobine, leur procede de preparation et leurs applications

L'invention a pour objet un procede de preparation de conjugues macromoleculaires hydrosolubles d'hemoglobine, caracterise en ce que : - on fixe, dans une premiere etape, des sites Z sur un polymere P, les sites Z contenant d'une part au moins une charge negative portee par exemple par des groupes sulfates et destinee a creer une liaison ionique avec l'hemoglobine, et contenant d'autre part au moins par exemple par un groupe carboxylique, et destine a creer une liaison covalente avec l'hemoglobine, - puis dans une seconde etape, on fait reagir le polymere P comportant le ou les sites Z avec de l'hemoglobine sous forme oxygenee, pour former d'une part au moins une liaison ionique entre l'un au moins des sites Z portes par le polymere et l'hemoglobine et d'autre part au moins une liaison covalente entre le meme susdit site Z porte par le polymere et l'hemoglobine. Les conjugues macromoleculaires obtenus par ce procede presentent pour l'oxygene une affinite inferieure a celle de l'hemoglobine ...

Method of retrofitting a finished shoe to provide additional cushioning material

A method of retrofitting a finished shoe to provide additional cushioning material. The method includes: providing a curable composition; providing the finished shoe; placing the curable composition directly on at least a portion of the finished shoe that is configured to contact a wearer's body when the finished shoe is being worn; and allowing the curable composition to cure and form a cushioning material adapted to facilitate wearing of the finished shoe with increased comfort.

Method of retrofitting a finished shoe to provide additional cushioning material

A method of retrofitting a finished shoe to provide additional cushioning material. The method includes: providing a curable composition; providing the finished shoe; placing the curable composition directly on at least a portion of the finished shoe that is configured to contact a wearer's body when the finished shoe is being worn; and allowing the curable composition to cure and form a cushioning material adapted to facilitate wearing of the finished shoe with increased comfort.

Particles which are surface coated with hyaluronan or one of the derivatives thereof and the use of same as biological vectors for active substances

Particles having a core based on at least one biodegradable organosoluble polymer. At least a part of the surface of the particles is coated with at least one hyaluronan or a derivative thereof, the hyaluronan being a water-soluble, amphiphilic hyaluronan of which the carboxylic functions are in part transformed to form hydrophobic groups. 1. A method of preparing particles encapsulating a hydrophobic active substance , comprising: dissolving a biodegradable polymer in en organic phase with the hydrophobic active substance to be encapsulated,', 'dissolving an amphiphilic hyaluronan in an aqueous phase, the aqueous phase being a dispersing medium for the organic phase, and', 'mixing the organic phase and the aqueous phase;, 'preparing a single emulsion includingevaporating off an organic solvent; andrecovering the particles encapsulating the hydrophobic active substance.2. The method of claim 1 , further comprising washing the particles with water.3. The method of claim 1 , farther comprising subjecting the particles to centrifugation or lyophilization.4. The method of claim 1 , wherein the organic phase is a solvent that is barely soluble in water.5. The method of claim 4 , wherein the organic solvent is methylene chloride or ethyl acetate.6. The method of claim 1 , further comprising incorporating a diagnostic compound into the particles.7. The method of claim 6 , wherein the diagnostic compound comprises at least one substance capable of being detected by X-rays claim 6 , fluorescence claim 6 , ultrasound claim 6 , substances nuclear magnetic resonance claim 6 , or radioactivity.8. The method of claim 6 , wherein incorporating the diagnostic material occurs during formation of the particles claim 6 ,9. A method of preparing particles encapsulating a hydrophilic active material claim 6 , comprising: the organic phase contains a biodegradable organosoluble polymer, and', 'the first aqueous phase contains the hydrophilic active material to be encapsulated;, ' ...

Particles which are surface coated with hyaluronan or one of the derivatives thereof and the use of same as biological vectors for active substances

The invention relates to particles comprising a core based on at least one biodegradable organo-soluble polymer. The inventive particles are characterised in that at least part of the surface thereof is coated with at least one hyaluronan or one of the derivatives thereof, said hyaluronan being a water-soluble, amphiphilic hyaluronan of which the carboxylic functions are in part transformed in order to form hydrophobic groups.

Method of retrofitting a finished shoe to provide additional cushioning material

A method of retrofitting a finished shoe to provide additional cushioning material. The method includes: providing a curable composition; providing the finished shoe; placing the curable composition directly on at least a portion of the finished shoe that is configured to contact a wearer's body when the finished shoe is being worn; and allowing the curable composition to cure and form a cushioning material adapted to facilitate wearing of the finished shoe with increased comfort.

Method of Retrofitting a Finished Shoe to Provide Additional Cushioning Material

A method of retrofitting a finished shoe to provide additional cushioning material. The method includes: providing a curable composition; providing the finished shoe; placing the curable composition directly on at least a portion of the finished shoe that is configured to contact a wearer's body when the finished shoe is being worn; and allowing the curable composition to cure and form a cushioning material adapted to facilitate wearing of the finished shoe with increased comfort.

Method of retrofitting a finished shoe to provide additional cushioning material

A method of retrofitting a finished shoe to provide additional cushioning material. The method includes: providing a curable composition; providing the finished shoe; placing the curable composition directly on at least a portion of the finished shoe that is configured to contact a wearer's body when the finished shoe is being worn; and allowing the curable composition to cure and form a cushioning material adapted to facilitate wearing of the finished shoe with increased comfort.

Particles which are surface coated with hyaluronan or one of the derivatives thereof and the use of same as biological vectors for active substances

Particles comprising a core based on at least one biodegradable organosoluble polymer. At least a part of the surface of the particles is coated with at least one hyaluronan or a derivative thereof, the hyaluronan being a water-soluble, amphiphilic hyaluronan of which the carboxylic functions are in part transformed to form hydrophobic groups.

MACROMOLECULAR CONJUGATES OF HEMOGLOBIN, THEIR PREPARATION PROCESS AND THEIR APPLICATIONS

Group III nitride photonic devices on silicon carbide substrates with conductive buffer interlay structure

An optoelectronic device with a Group III Nitride active layer is disclosed that comprises a silicon carbide substrate; an optoelectronic diode with a Group III nitride active layer; a buffer structure selected from the group consisting of gallium nitride and indium gallium nitride between the silicon carbide substrate and the optoelectronic diode; and a stress-absorbing structure comprising a plurality of predetermined stress-relieving areas within the crystal structure of the buffer structure, so that stress-induced cracking that occurs in the buffer structure occurs at predetermined areas rather than elsewhere in the buffer structure.

Identifying companion gestures and behavior

This disclosure describes a system for identifying users and/or their companions, utilizing the behavior and gestures of a user's companion to assist the user, and developing user paths based on user and/or companion preferences. A companion profile may be established to identify the companion and associated the companion with the user. Likewise, a user pattern that includes both the user and the companion may be established and used to track the location of the user and/or companion while in the materials handling facility.

HEMOGLOBIN MACROMOLECULAR CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATIONS

L'INVENTION A POUR OBJET UN CONJUGUE MACROMOLECULAIRE HYDROSOLUBLE D'HEMOGLOBINE CARACTERISE EN CE QU'IL EST CONSTITUE -D'UNE PART, PAR DE L'HEMOGLOBINE, -D'AUTRE PART, PAR UN POLYMERE P HYDROSOLUBLE COMPORTANT DES GROUPES POLAIRES, LEQUEL CONJUGUE MACROMOLECULAIRE COMPORTE DES SITES Z ATTACHES SUR LE POLYMERE P ET CONTENANT AU MOINS UNE CHARGE NEGATIVE PORTEE PAR EXEMPLE PAR DES GROUPES SULFATES, LE POLYMERE P ETANT RELIE A L'HEMOGLOBINE -D'UNE PART, PAR L'INTERMEDIAIRE D'AU MOINS UNE LIAISON ETABLIE ENTRE L'UN AU MOINS DES SITES Z PORTES PAR LE POLYMERE ET L'HEMOGLOBINE, -ET, D'AUTRE PART, PAR L'INTERMEDIAIRE D'AU MOINS UNE LIAISON COVALENTE ETABLIE ENTRE LE POLYMERE ET L'HEMOGLOBINE, OU ENTRE L'UN AU MOINS DES SITES Z PORTES PAR LE POLYMERE ET L'HEMOGLOBINE. LES CONJUGUES MACROMOLECULAIRES SELON L'INVENTION PRESENTENT POUR L'OXYGENE UNE AFFINITE INFERIEURE A CELLE DE L'HEMOGLOBINE LIBRE. THE SUBJECT OF THE INVENTION A HYDROSOLUBLE MACROMOLECULAR CONJUGATE OF HEMOGLOBIN CHARACTERIZED IN THAT IT CONSTITUTES -On the one hand, BY HEMOGLOBIN, -On the other hand, BY A HYDROSOLUBLE POLYMER P CONTAINING POLAR GROUPS, WHICH MACROMOLECULAR CONJUGATE CONTAINS Z SITES ATTACHED TO POLYMER P AND CONTAINING AT LEAST ONE NEGATIVE CHARGE CARRIED FOR EXAMPLE BY SULPHATE GROUPS, POLYMER P BEING CONNECTED TO HEMOGLOBIN - ON THE ONE HAND, THROUGH AT LEAST ONE LINK ESTABLISHED BETWEEN AT LEAST ONE OF THE Z SITES CARRIED BY POLYMER AND HEMOGLOBIN, -AND, ON THE OTHER HAND, THROUGH AT LEAST ONE COVALENT LINK ESTABLISHED BETWEEN POLYMER AND HEMOGLOBIN, OR BETWEEN AT LEAST ONE OF THE Z SITES CARRIED BY POLYMER AND HEMOGLOBIN. MACROMOLECULAR CONJUGATES ACCORDING TO THE INVENTION SHOW LOWER AFFINITY FOR OXYGEN THAN THAT OF FREE HEMOGLOBIN.

Chemically modified haemoglobin, its preparation, aqueous solutions containing it and their use

The modified haemoglobin according to the invention is characterised in that each modified haemoglobin molecule carries at its periphery chemically bound macromolecular grafts which are hydrophilic, haemocompatible, not very biodegradable or non-biodegradable in plasma medium, non-antigenic and non-toxic, of formula: A-L, in which: A is a chemically inactive terminal organic radical and L is a linear, hydrophilic macromolecular chain whose molecular mass is between 2,000 and 50,000 g, preferably a radical (M)x-X-, in which (M)x is in particular a polyoxyethylene chain and X an "arm" such as -NH-CO-CH2-CH2, -O-CH2- or -OCO-CH2-CH2-. This haemoglobin is characterised by a Barcroft curve which is very similar to that for native haemoglobin. It can be used as a reversible oxygen carrier, especially during transfusional procedures.

INSTALLATION FOR THE ASSEMBLY AND, PARTICULARLY, THE PINING OF BODIES OF MOTOR VEHICLES

MACROMOLECULAR CONJUGATES OF HEMOGLOBIN, THEIR PREPARATION PROCESS AND THEIR APPLICATIONS

METHOD, DEVICE AND APPARATUS FOR OBTAINING AN IMPRESSION OF THE SURFACE OF AN OBJECT OR A PART OF THE BODY.

IMPROVEMENT TO AUBES OF COOLED TURBINES

PERFECTIONNEMENT AUX AUBES DE TURBINES REFROIDIES, COMPORTANT DEUX CAVITES ALIMENTEES PAR UN DEBIT DE FLUIDE, DONT UNE CAVITE AMONT A ECOULEMENT RADIAL ET UNE CAVITE AVAL DIVISEE EN DEUX ZONES D'ECOULEMENT RADIAL ET TANGENTIEL VERS LE BORD DE FUITE. LA CAVITE AMONT 1 PRESENTE DES ORGANES DEFLECTEURS 11 D'ECOULEMENT ET LA CAVITE AVAL 2 COMPORTE, DANS LA ZONE CENTRALE POUR L'ECOULEMENT RADIAL DU FLUIDE, DES PONTETS 12 DE GRANDE SECTION, ALORS QUE DANS LA ZONE DE BORD DE FUITE 3 A ECOULEMENT TANGENTIEL LADITE CAVITE AVAL COMPORTE DES PONTETS 13 DE PLUS FAIBLE SECTION COMPLETES PAR DES ORGANES DEFLECTEURS 14 GUIDANT L'ECOULEMENT RADIAL, TANGENTIELLEMENT VERS LES ORIFICES DU BORD DE FUITE 3. L'INVENTION EST UTILISEE POUR LE REFROIDISSEMENT DES AUBES DE TURBINES DE TURBOMACHINES. IMPROVEMENT TO COOLED TURBINE BLADES, INCLUDING TWO CAVITIES SUPPLIED BY A FLUID FLOW, INCLUDING AN UPSTREAM CAVITY WITH RADIAL FLOW AND A DOWNSTREAM CAVITY DIVIDED INTO TWO ZONES OF RADIAL FLOW AND TANGENTIAL TOWARD THE LEAKING EDGE. UPSTREAM CAVITY 1 HAS FLOW DEFLECTORS 11 AND DOWNSTREAM CAVITY 2 INCLUDES, IN THE CENTRAL ZONE FOR RADIAL FLUID FLOW, LARGE SECTION BRIDGES 12, WHILE IN LEAKING EDGE ZONE 3 HAS FLOW TANGENTIAL THE SAID DOWNSTREAM CAVITY CONTAINS BRIDGES 13 WITH LOWEST SECTION COMPLETED BY DEFLECTORS 14 GUIDING THE RADIAL FLOW, TANGENTIALLY TOWARD THE ORIFICES OF THE LEAKING EDGE 3. THE INVENTION IS USED FOR COOLING THE BLADES OF TURBINE TURBINES.

METHOD, DEVICE AND APPARATUS FOR OBTAINING A FOOTPRINT OF THE SURFACE OF AN OBJECT OR PART OF THE BODY

La présente invention concerne un procédé, divers dispositifs ainsi qu'un appareillage pour l'obtention d'une empreinte de la surface d'un objet (4) ou d'une partie du corps. Le procédé, par lequel une matière modelable (3) est disposée entre ladite surface et un côté d'une membrane déformable (2), susceptible d'épouser la forme de ladite surface sous l'effet de la pression qu'y exerce ledit objet (4) ou ladite partie du corps, est caractérisé en ce que des moyens pneumatiques commandés sont agencés de l'autre côté de ladite membrane (2) pour délivrer une contrepression continûment variable permettant de contrôler en permanence l'amplitude des déformations de ladite matière modelable (3). L'invention est notamment destinée à la réalisation de semelles anatomiques ou correctrices. The present invention relates to a method, various devices and an apparatus for obtaining an imprint of the surface of an object (4) or of a part of the body. The method, by which a moldable material (3) is disposed between said surface and one side of a deformable membrane (2) capable of conforming to the shape of said surface under the effect of the pressure exerted by said object therein (4) or said part of the body, is characterized in that controlled pneumatic means are arranged on the other side of said membrane (2) to deliver a continuously variable back pressure making it possible to permanently control the amplitude of the deformations of said material moldable (3). The invention is particularly intended for the production of anatomical or corrective insoles.

Installation for the assembly, and more particularly the spot welding of automotive vehicle bodies

Installation pour l'assemblage et, notamment, pour l'épinglage de carrosseries de véhicules automobiles, comportant des chariots de support des carrosseries à assembler par soudure et des moyens pour déplacer ces chariots vers une station d'assemblage pourvue de moyens de soudage. Cette installation est caractérisée en ce qu'elle comporte un bâti rigide et fixe, un cadre rigide mobile sur le bâti et au moins deux portiques fixés rigidement sur ce cadre, chaque portique comportant les moyens de positionnement et de maintien propres à un modèle de carrosserie à souder, des moyens pour déplacer le cadre sur le bâti parallèlement au sens de déplacement des chariots et des moyens pour verrouiller le cadre par rapport au bâti afin de positionner l'un ou l'autre des portlques dans la station d'assemblage.

Macromolecular conjugates of hemoglobin, a procedure for their preparation and their uses

The subject of the invention is a water-soluble macromolecular conjugate of hemoglobin characterized in that it is constituted on the one hand, by hemoglobin, on the other, by a water-soluble polymer P containing polar groups, this macromolecular conjugate contains Z sites, bound to the polymer P and containing at least one negative charge carried for example by sulfate groups, the polymer P being bound to hemoglobin on the one hand, through the intermediary of at least one linkage established between at least one of the Z sites contained in the polymer and hemoglobin, and, on the other, through the intermediary of at least one covalent linkage established between the polymer and hemoglobin, or between at least one of the Z sites contained in the polymer and hemoglobin. The macromolecular conjugates according to the invention exhibit a lower affinity for oxygen than that of free hemoglobin.

METHOD FOR REMOVING A FINISHED SHOE FOR SUPPLYING ADDITIONAL SHOCK ABSORBER MATERIAL

Automated and periodic updating of item images data store

This disclosure describes a system for automatically updating item image information stored in an item images data store and used for processing captured images to identify items represented in those images. In one implementation, once an identity of an item has been verified, captured images of that item are associated with the item and stored in the item images data store. As a result, the item images data store is updated each time an image of the item is captured and the identity of the item is verified.

PARTIAL MULTI-CUSTOMIZABLE DISCHARGE SOLE TO REDUCE OR REMOVE LOCALIZED PRESSURES UNDER FOOT AND RETRO-CALCANEENNES WHEN PRESENTING BONE EPINE OR VARIOUS PLANTALGIES

Semelle partielle de décharge multi-personnalisable pour réduire ou supprimer les pressions localisées sous le pied et/ou rétro-calcanéennes lors de la présence d'épines osseuses (esc) (erc) par exemple ou de plantalgies douloureuses multiples. Orthèse plantaire sous forme d'une semelle partielle positionnée sous le pied à l'aplomb du médiotarse et du tarse postérieur permettant, selon les matériaux utilisés, de traiter les talalgies d'origines mécaniques du type appelée populairement « épines sous et/ou rétro-calcanéennes », appelées aussi « calcification d'insertion ». Cette semelle partielle, ou demi-semelle, d'épaisseur constante pour un même individu, pourra varier en épaisseur et en compressibilité. La matière qui la compose, EVA, PVC, PE, latex, liège-mousse, thermoliège ou mousse d'amortissement varie de 8 à 10 mm en épaisseur et de 8 à 65 Shores (A) en compressibilité en fonction du poids du patient. Cette compressibilité est directement liée au poids du patient, de 40 kg à plus de 180 kg. La taille de la semelle partielle et des pièces amovibles intrinsèques correspondent à la pointure du patient, du 35 au 49 (tranches de 2 à 4 pointures par taille). Les sept pièces amovibles sont réalisées avant réglage dans la même matière que la semelle partielle, ou d'une compressibilité forte de 8 à 12 Shores (A), pour réduire considérablement l'appui sous la ou les zones douloureuses, repérées par palpation et visualisées sur le podogramme de chaque pied par des pastilles adhésives de faible diamètre, visibles sur l'empreinte. Les semelles partielles sont recouvertes par collage d'une matière extensible et lavable, en EVA, PVC, PE, latex ou équivalent, toutes de nature extensible. Un blocage talon (6) empêche la semelle partielle de glisser en avant (chaussures fermées). Une pastille auto-agrippante Velcro empêchera la semelle d'être projetée en arrière (chaussures ouvertes). Les réglages de départ pourront être modifié ...

Group iii nitride photonic devices on silicon carbide substrates with conductive buffer interlayer structure

An optoelectronic device with a Group III Nitride active layer is disclosed that comprises a silicon carbide substrate; an optoelectronic diode with a Group III nitride active layer; a buffer structure selected from the group consisting of gallium nitride and indium gallium nitride between the silicon carbide substrate and the optoelectronic diode; and a stress-absorbing structure comprising a plurality of predetermined stress-relieving areas within the crystal structure of the buffer structure, so that stress-induced cracking that occurs in the buffer structure occurs at predetermined areas rather than elsewhere in the buffer structure.

INSTALLATION FOR ASSEMBLING MULTIPLE BODY MODELS OF THE SAME TYPE OF MOTOR VEHICLE

A.CETTE INSTALLATION COMPORTE DES MOYENS DE POSITIONNEMENT ET DE MAINTIEN DES PIECES DE CARROSSERIE, AINSI QUE DES DISPOSITIFS POUR LE SOUDAGE DE CES PIECES LES UNES AUX AUTRES. B.CETTE INSTALLATION EST CARACTERISEE EN CE QU'ELLE COMPORTE UN BATI RIGIDE FIXE POURVU A SA PARTIE SUPERIEURE D'UN CHEMIN DE DEPLACEMENT HORIZONTAL POUR DES CHARIOTS DITS CHARIOTS SUPERIEURS COMPORTANT CHACUN LES ELEMENTS DE POSITIONNEMENT ET DE MAINTIEN DES PIECES DE LA PARTIE HAUTE D'UN MODELE DETERMINE DE CARROSSERIE DE VEHICULE AUTOMOBILE ET A SA PARTIE INFERIEURE D'UN ELEVATEUR 8, RECEVANT DES ORGANES DE CENTRAGE COOPERANT AVEC LES PIECES DE LA PARTIE BASSE D'UN TYPE DE CARROSSERIE DE VEHICULE AUTOMOBILE COMMUN A PLUSIEURS MODELES. A. THIS INSTALLATION CONTAINS MEANS OF POSITIONING AND HOLDING BODY PARTS, AS WELL AS DEVICES FOR WELDING THESE PARTS TO ONE ANOTHER. B. THIS INSTALLATION IS CHARACTERIZED IN THAT IT INCLUDES A FIXED RIGID BUILDING PROVIDED AT ITS UPPER PART WITH A HORIZONTAL MOVEMENT PATH FOR TROLLEYS CALLED UPPER TROLLEYS EACH INCLUDING THE POSITIONING AND HOLDING ELEMENTS OF THE PART OF THE PART A DETERMINED MODEL OF MOTOR VEHICLE BODYWORK AND ITS LOWER PART OF A LIFT 8, RECEIVING CENTERING MEMBERS COOPERATING WITH THE PARTS OF THE LOWER PART OF A TYPE OF MOTOR VEHICLE BODYWORK COMMON TO SEVERAL MODELS.

Notifying users to provide picked items to a drop off location for processing

The application describes a system and process for anticipating when a user will leave a selection area within a materials handling facility and determining if a notification requesting that the user provide a tote of picked items to a drop off location should be presented to the user. For example, a user may be asked to provide items picked from a selection area for processing, such as packing, while the user is picking items from other selection areas of a materials handling facility.

Group iii nitride photonic devices on silicon carbide substrates with conductive buffer interlayer structure

An optoelectronic device with a Group III nitride active layer is disclosed that comprises a silicon carbide substrate; an optoelectronic diode with a Group III nitride active layer; a buffer structure selected from the group consisting of galllium nitride and indium gallium nitride between the silicon carbide substrate and the optoelectronic diode; and a stress-absorbing structure comprising a plurality of predetermined stress-relieving areas within the crystal structure of the buffer structure, so that stress-induced cracking that occurs in the buffer structure occurs at predetermined areas rathen than elsewhere in the buffer structure.

INSTALLATION FOR ASSEMBLY AND, IN PARTICULAR, BODY WELDING OF AUTOMOTIVE VEHICLES

A.INSTALLATION POUR L'ASSEMBLAGE ET, NOTAMMENT, POUR L'EPINGLAGE DE CARROSSERIES DE VEHICULES AUTOMOBILES, COMPORTANT DES CHARIOTS 2 DE SUPPORT DES CARROSSERIES 1 A ASSEMBLER PAR SOUDURE ET DES MOYENS 4 POUR DEPLACER CES CHARIOTS VERS UNE STATION D'ASSEMBLAGE POURVUE DE MOYENS DE SOUDAGE. B.INSTALLATION CARACTERISEE EN CE QU'ELLE COMPORTE UN BATI RIGIDE ET FIXE 9, UN CADRE RIGIDE 14 MOBILE SUR LE BATI 9 ET AU MOINS DEUX PORTIQUES 15, 16 FIXES RIGIDEMENT SUR CE CADRE 14, CHAQUE PORTIQUE COMPORTANT LES MOYENS 15, 16 DE POSITIONNEMENT ET DE MAINTIEN PROPRES A UN MODELE DE CARROSSERIE A SOUDER, DES MOYENS 17, 18, 19, 20, 21, 22 POUR DEPLACER LE CADRE SUR LE BATI PARALLELEMENT AU SENS DE DEPLACEMENT DES CHARIOTS 2 ET DES MOYENS 23, 24, 25, 26 POUR VERROUILLER LE CADRE 14 PAR RAPPORT AU BATI AFIN DE POSITIONNER L'UN OU L'AUTRE DES PORTIQUES 15, 16 DANS LA STATION D'ASSEMBLAGE. A.INSTALLATION FOR THE ASSEMBLY AND, IN PARTICULAR, FOR THE PINNING OF MOTOR VEHICLE BODIES, INCLUDING SUPPORT TROLLEYS 2 FOR BODYWORK 1 TO BE ASSEMBLED BY WELDING AND MEANS 4 FOR MOVING THESE TROLLEYS TOWARDS AN ASSEMBLY STATION FOR AN ASSEMBLY STATION WELDING MEANS. B. INSTALLATION CHARACTERIZED IN THAT IT INCLUDES A RIGID AND FIXED FRAME 9, A RIGID FRAME 14 MOBILE ON FRAME 9 AND AT LEAST TWO GATES 15, 16 FIXED RIGIDLY ON THIS FRAME 14, EACH GATE WITH THE MEANS 15, 16 OF POSITIONING AND MAINTENANCE CLEAN TO A BODYWORK MODEL TO WELD, MEANS 17, 18, 19, 20, 21, 22 TO MOVE THE FRAME ON THE FRAME PARALLEL IN THE DIRECTION OF MOVEMENT OF TROLLEYS 2 AND MEANS 23, 24, 25, 26 TO LOCK THE FRAME 14 IN RELATION TO THE FRAME IN ORDER TO POSITION ONE OR THE OTHER OF THE GATES 15, 16 IN THE ASSEMBLY STATION.

Hemoglobin macromolecular conjugates, their preparation process and their uses

L'invention a pour objet un conjugué macromoléculaire hydrosoluble d'hémoglobine caractérisé en ce qu'il est constitué - d'une part, par de l'hémoglobine, - d'autre part, par polymère P hydrosoluble comportant des groupes polaires, lequel conjugué macromoléculaire comporte des groupes Z attachés par le polymère P et contenant au moins une charge négative portée par exemple par des groupes sulfates, le polymère P étant relié à l'hémoglobine, - d'une part, par l'intermédiaire d'au moins une liaison établie entre l'un au moins des groupes Z portés par le polymère et l'hémoglobine, et - d'autre part, par l'intermédiaire d'au moins une liaison covalente établie entre le polymère et l'hémoglobine, ou entre l'un au moins des groupes Z portés par le polymère et l'hémoglobine. Les conjugués macromoléculaires selon l'invention présentent pour l'oxygène une affinité inférieure à celle de l'hémoglobine libre.

Generation of footprint data for items

An item stowed at an inventory location may rest or be supported by a surface, such as a shelf, that includes an optical sensor array. The optical sensor array comprises a plurality of optical sensors that detect light intensity values. When a light source illuminates the item resting on the surface, a footprint or shadow is cast by the item onto the surface. Such a shadow is detected by the light intensity values at the optical sensors in the optical sensor array. Once the shadow is detected, information about the area, shape, and perimeter of the shadow can be determined and saved as footprint data for a single item. Such a process can be performed at intake of the item to the facility and later accessed to determine a quantity of the item on a shelf of a facility.

INSTALLATION FOR ASSEMBLING SEVERAL BODY MODELS OF THE SAME TYPE OF MOTOR VEHICLE

Group iii nitride photonic devices on silicon carbide substrates with conductive buffer interlayer structure

An optoelectronic device with a Group III nitride active layer is disclosed that comprises a silicon carbide substrate; an optoelectronic diode with a Group III nitride active layer; a buffer structure selected from the group consisting of galllium nitride and indium gallium nitride between the silicon carbide substrate and the optoelectronic diode; and a stress-absorbing structure comprising a plurality of predetermined stress-relieving areas within the crystal structure of the buffer structure, so that stress-induced cracking that occurs in the buffer structure occurs at predetermined areas rathen than elsewhere in the buffer structure.

Gas turbine blade with cooling passages - holes parallel to blade axis provide surface layer of cool air

The blade of an axial flow gas turbine has a fir tree type root (1) with a platform (3) carrying a profiled section (4) surmounted by a platform (6) with sealing ribs (7). The upper half of the profiled section is reduced in area of cross section. Holes (10) of small diameter extend upwards from the tip of the root (1) to break through the blade surface in the region (8) of the reduction in cross section. The holes form elliptical openings (12) in the blade surface. Cooling air is supplied to the holes (10) and emerges from the openings (12) to form a cool layer over the upper part of the blade.

MACROMOLECULAR HAEMOGLOBIN COMPLEXES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE.

The invention relates to a method of preparation of water-soluble macromolecular conjugates of haemoglobin, wherein: - in a first step, sites Z are bound to a polymer P, the sites Z containing on the one hand at least one negative charge carried, for example, by sulphate groups and intended for creating an ionic bond with haemoglobin, and containing on the other hand at least ..... for example, by a carboxyl group and intended for creating a covalent bond with haemoglobin, - then, in a second step, the polymer P containing the site or sites Z is reacted with haemoglobin in oxygenated form, to form, on the one hand at least one ionic bond between at least one of the sites Z carried by the polymer and the haemoglobin, and on the other hand at least one covalent bond between the abovementioned same site Z carried by the polymer and the haemoglobin. <??>The macromolecular conjugates obtained by this method possess a lower affinity for oxygen than that of free haemoglobin.

Basket-type carrier for articles of various sizes

Abstract of the Disclosure A basket-type carrier in which the cells are longer than they are wide in order to receive articles which areelongated in transverse cross section. The blank for forming the carrier contains spaced centrally located support panel sections which are foldably connected to riser panel sections and to the ends of partition straps. The folds connecting the center support panel sections to the partition straps are located between the folds connecting the side panels to the end panel sections and the folds connecting the end panel sections to the riser panel sections.

MACROMOLECULAR HAEMOGLOBIN CONJUGATES, PROCESSES FOR THEIR PRODUCTION AND THEIR USES.

Device transitions between inactive and active states

Described is a method for determining when to transition devices between different states based on determined potential activity in an area near the devices. When the potential for activity near an input device is below a threshold, the device is maintained in an inactive state. When the potential for activity near the device exceeds the threshold, the device is transitioned to an active state before the potential activity can occur near the device. Likewise, when the device is in an active state, the implementations described herein provide the ability to determine when to begin and end transmission of data from the device to a remote computing resource for processing. For example, obtained video may be processed locally to determine if an activity is occurring. If an activity is occurring, relevant data is sent to a remote computing resource to determine if an action has been performed during the activity.

Dome-like structure and kit of parts therefor

A kit of parts for forming a structure which may be a play structure or a shelter, and which is at least partially of dome-like shape and which can resemble an igloo, comprises a series of side panels of generally trapezoidal shape each with side edges which are at least partially bowed outwardly and are capable of being joined edge-to-edge to adjacent side panels when curved to conform to said dome-like shape. The side panels are longitudinally flexible, and each has an upper end portion which is pleated to allow the upper edges of panels to be pushed together as the panels are joined. A convex top closure is provided for fitting over the top edges of the panels, and the pleated upper end portions allow ventilation around the edges of the closure.

METHOD FOR REMOVING A FINISHED SHOE FOR SUPPLYING ADDITIONAL SHOCK ABSORBER MATERIAL

L'invention concerne un procédé de refaçonnage d'une chaussure finie, pour fournir un matériau amortisseur supplémentaire. Le procédé comprend les étapes consistant à fournir une composition polymérisable ; à fournir la chaussure finie ; à placer la composition polymérisable directement sur au moins une partie de la chaussure finie qui est configurée pour être au contact du corps d'un utilisateur, lorsque la chaussure finie est portée ; et à permettre à la composition polymérisable de se polymériser et de former un matériau amortisseur adapté, pour faciliter le port de la chaussure finie offrant un confort accru. The invention relates to a method of reshaping a finished shoe, to provide additional cushioning material. The method comprises the steps of providing a polymerizable composition; to provide the finished shoe; placing the polymerizable composition directly on at least a portion of the finished shoe that is configured to contact the body of a user when the finished shoe is worn; and allowing the polymerizable composition to polymerize and form a suitable cushioning material to facilitate wear of the finished shoe providing increased comfort.

Sensor data fusion for increased reliability

An event at a shelf, such as a user interacting with items on the shelf, may be detected using sensors associated with the shelf. Hypotheses to describe the event are generated based on the collected sensor data. However, hypotheses determined based on only one type of sensor data may not have a confidence value that is sufficiently reliable. Hypotheses derived from different sensor types may be combined to generate new hypotheses that have higher confidence values. For example, hypotheses based on image data may be combined with hypotheses based on weight data to produce hypotheses with higher confidence values that are sufficiently reliable. A hypothesis, from the set of combined hypotheses, having the highest confidence value may then be used to describe the interaction at the shelf, such as identifying the item and quantity of item the user interacted with during the event.

Particules revetues en surface de hyaluronane ou d'un de ses derives et leur utilisation a titre de vecteurs biologiques pour des matieres actives

« Particules revêtues en surface de hyaluronane ou d'un de ses dérivés et le ur utilisation á titre de vecteurs biologiques pour des matières actives » La présente invention concerne des particules dont le c.oelig.ur est á base d'a u moins un polymère organosoluble biodégradable, caractérisées en ce qu'elles sont revêtues, au moins partiellement en surface d'au moins un hyaluronane o u de l'un de ses dérivés, ledit hyaluronane étant un hyaluronane amphiphile, hydrosoluble et dont les fonctions carboxyliques sont en partie transformées pour figurer des groupes hydrophobes.

Particules revetues en surface de hyaluronane ou d'un de ses derives et leur utilisation a titre de vecteurs biologiques pour des matieres actives

« Particules revêtues en surface de hyaluronane ou d'un de ses dérivés et leur utilisation á titre de vecteurs biologiques pour des matières actives » La présente invention concerne des particules dont le c.oelig.ur est á base d'au moins un polymère organosoluble biodégradable, caractérisées en ce qu'elles sont revêtues, au moins partiellement en surface d'au moins un hyaluronane ou de l'un de ses dérivés, ledit hyaluronane étant un hyaluronane amphiphile, hydrosoluble et dont les fonctions carboxyliques sont en partie transformées pour figurer des groupes hydrophobes.

Particles which are surface coated with hyaluronan or one of the derivatives thereof and the use of same as biological vectors for active substances

Particules enrobees avec de la hyluronane ou un de ces derives et son utilisation comme vecteurs biologiques pour les principes actifs

« Particules revêtues en surface de hyaluronane ou d'un de ses dérivés et leur utilisation á titre de vecteurs biologiques pour des matières actives » La présente invention concerne des particules dont le cœur est á base d'au moins un polymère organosoluble biodégradable, caractérisées en ce qu'elles sont revêtues, au moins partiellement en surface d'au moins un hyaluronane ou de l'un de ses dérivés, ledit hyaluronane étant un hyaluronane amphiphile, hydrosoluble et dont les fonctions carboxyliques sont en partie transformées pour figurer des groupes hydrophobes.

Installazione per l assemblaggio didiversi modelli di carrozzerie di uno stesso tipo di autoveicolo

Selective transmission of data

Described is a method for determining when to transition devices between different states based on determined potential activity in an area near the devices. When the potential for activity near an input device is below a threshold, the device is maintained in an inactive state. When the potential for activity near the device exceeds the threshold, the device is transitioned to an active state before the potential activity can occur near the device. Likewise, when the device is in an active state, the implementations described herein provide the ability to determine when to begin and end transmission of data from the device to a remote computing resource for processing. For example, obtained video may be processed locally to determine if an activity is occurring. If an activity is occurring, relevant data is sent to a remote computing resource to determine if an action has been performed during the activity.

Dome-like structure and kit of parts therefor

A kit of parts for forming a structure which may be a play structure or a shelter, and which is at least partially of dome-like shape and which can resemble an igloo, comprises a series of side panels of generally trapezoidal shape each with side edges which are at least partially bowed outwardly and are capable of being joined edge-to-edge to adjacent side panels when curved to conform to said dome-like shape. The side panels are longitudinally flexible, and each has an upper end portion which is pleated to allow the upper edges of panels to be pushed together as the panels are joined. A convex top closure is provided for fitting over the top edges of the panels, and the pleated upper end portions allow ventilation around the edges of the closure.

Item tracking within a facility

This disclosure describes a system for determining an estimated user departure time from a materials handling facility. For example, a user may enter a materials handling facility to pick one or more items from the materials handling facility. Those items may be provided to an agent for processing, such as packing, while the user picks other items within the materials handling facility. To ensure that the items are processed in a timely manner and made available to the user when the user is ready to depart from the materials handling facility, the implementations discussed determine an anticipated user departure time and compare that time with an estimated processing time needed to process the items.

Automated and periodic updating of item images data store

This disclosure describes a system for automatically updating item image information stored in an item images data store and used for processing captured images to identify items represented in those images. In one implementation, once an identity of an item has been verified, captured images of that item are associated with the item and stored in the item images data store. As a result, the item images data store is updated each time an image of the item is captured and the identity of the item is verified.