14-06-2012 дата публикации
Номер: US20120149656A1
Автор:
Li Fu,
Hong Liu,
Mingming Lu,
Qi Lu,
Seong Tae Cho,
Wanzhe Cui,
FU LI,
LIU HONG,
LU MINGMING,
LU QI,
CHO SEONG TAE,
CUI WANZHE
Принадлежит:
A preparation of a kind of 20(R)-ginsenoside Rg3 medicinal composition aqueous solution containing ginsenoside Rg3 0.5˜10 mg/ml: add 0.1-5% of ginsenoside solution to 0.1˜30% of adjuvant A, B{circle around (1)}{circle around (2)}{circle around (5)} at the temperature of 40˜100° C., the ratio of these two is 1:1˜300, add water after the solvent is recycled under reduced pressure; another kind of 20(R)-ginsenoside Rg3 medicinal composition aqueous solution contains 0.1˜2 mg/ml of 20 (R) of the ginsenoside Rg3, the preparation: add 0.1˜5% of ginsenoside solution to 20˜65% of adjuvant B{circle around (3)}{circle around (4)} at the temperature of 60˜100° C., main material to adjuvant B=1:100˜400, add water after the solvent is recycled under reduced pressure. The above 20 (R) ginsenoside Rg3 composition aqueous solution and the powder after lyophilizaton can be used to prepare injectable, oral administration and external use, and the bioactivity of these preparations is high, and with the actions of anti cancer, efficacy potentiation and toxicity attenuation effects of the combined chemical or radiation therapy of tumor, enhancement of human immune functions, improvement of human memory, anti fatigue, and detumescence, pain relieving. 1. An aqueous solution of a medicinal composition comprising a 20(R)-ginsenoside Rg3 , wherein the content of the ginsenoside Rg3 in the solution is 0.5˜10 mg/mL.2. A preparation process of an aqueous solution of a medicinal composition comprising a 20(R)-ginsenoside Rg3 , comprising step 1 , step 2 , step 3 and step 4 ,wherein step 1 comprises dissolving the 20(R)-ginsenoside Rg3 in a mixture of an organic solvent, and forming a solution comprising 0.1˜5% the ginsenoside;wherein step 2 comprises dissolving adjuvant A and adjuvant B {circle around (1)}{circle around (2)}{circle around (5)} in water, respectively, and forming an aqueous solution comprising 0.1˜30 wt % adjuvant A and adjuvant B;wherein step 3 comprises adding all the ...
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