SYSTEM FOR THE CONTROLLING OF A CUTTING PRESS FOR BLATTFÖRMIGE MATERIALS

Control device of a machine for cutting blanks from a sheet material.

METHOD AND DEVICE FOR INTRODUCING PLATES FOR A MACHINE FOR PROCESSING SHEETS OF CORRUGATED CARDBOARD OR MICRO-FLUTE.

La présente invention concerne un procédé d'introduction d'éléments en plaque de carton ondulé ou à micro-cannelure, dans une machine de transformation. Selon l'invention, un paquet d'éléments en plaque (32) est déposé sur un ascenseur (31) lors d'une phase de dépôt, l'ascenseur portant le paquet (32) monte progressivement lors d'une phase de montée, un effet vacuum est appliqué sur la surface supérieure de l'élément en plaque (35) au sommet du paquet (32) lors d'une phase de saisie et l'élément en plaque (35) saisi est transporté vers la machine de transformation lors d'une phase de transport. Optionnellement le procédé peut comprendre une phase non-stop et une phase de dépilage. L'invention concerne également un dispositif d'introduction (30) permettant de mettre en œuvre un procédé selon l'invention, comprenant un ascenseur (31), un dispositif de transport vacuum (34) et un contrôleur (33). Le dispositif (30) comprend optionnellement un dispositif non-stop (45) et un dispositif de dépilage (50). L'invention permet d'introduire des éléments en plaque de carton ondulé ou à micro-cannelure sans en détériorer le bord frontal ou la surface. The present invention relates to a method of introducing elements of corrugated cardboard or micro-groove, in a processing machine. According to the invention, a pack of plate elements (32) is deposited on an elevator (31) during a deposition phase, the elevator carrying the package (32) rises gradually during a climbing phase, a vacuum effect is applied to the upper surface of the plate member (35) at the top of the packet (32) during a gripping phase and the gripped plate member (35) is transported to the converting machine at a transport phase. Optionally, the method may comprise a non-stop phase and an unstacking phase. The invention also relates to an introduction device (30) for implementing a method according to the invention, comprising an elevator (31), a ...

METHOD FOR RECEIVING PLATES FOR CONVERTING MACHINE OF PLATES AND INKJET PRINTING MACHINE.

La présente invention concerne un procédé de réception d'éléments en plaque (1) pour une machine d'impression numérique (20). Selon l'invention, - lors d'une étape de début de paquet au moins un élément en plaque (1) est transporté jusqu'à une butée (31) puis déposé sur un ascenseur (32) pour former la base d'un paquet (33) dont le bord frontal correspond à la butée (31) ; - lors d'une étape de constitution de paquet, les éléments en plaques (1) sont transportés jusqu'à une position correspondant au bord arrière d'un paquet (33) porté par l'ascenseur (32), l'ascenseur descendant progressivement au fur et à mesure de la constitution du paquet (33) ; - lors d'une étape de fin de paquet le déplacement de certains éléments en plaque (1) destinés à former la base du prochain paquet (33) est interrompu et les éléments en plaque (1) en aval de l'interruption sont transportés jusqu'à une position correspondant au bord arrière d'un paquet (33) porté par l'ascenseur (32) ; - lors d'une étape d'évacuation de paquet, le paquet (33) est évacué et l'ascenseur (32) remonte en position haute. L'invention concerne également un dispositif de réception (30) d'éléments en plaque (1) pour machine d'impression numérique (20) sur des éléments en plaque de carton ondulé ou à micro-cannelure permettant de mettre en œuvre un procédé selon l'invention. L'invention permet d'adapter la réception des éléments en plaque (1) aux spécificités de l'impression numérique. The present invention relates to a method for receiving plate elements (1) for a digital printing machine (20). According to the invention, - during a start of packet step at least one plate element (1) is transported to a stop (31) and then deposited on an elevator (32) to form the base of a package (33) whose front edge corresponds to the stop (31); during a step of forming a package, the plate elements (1) are transported to a ...

A device for controlling a machine for cutting blanks from a sheet material

DEVICE FOR CONTROLLING MACHINE FOR CUTTING BLANKS FROM SHEET MATERIAL

PURPOSE: A device for controlling a machine is provided to reduce error by using a set of cutting tools interchangeable in dependence on the blanks to be cut and elements adjustable in dependence on the jobs to be done by each tool. CONSTITUTION: A control device controls operation of a machine(5) for cutting blanks from a sheet material, wherein the machine comprises a set of cutting tools interchangeable in dependence on the blanks to be cut, elements adjustable in dependence on the jobs to be done by each tool, and elements for actuating the adjustable tools. The control device comprises a memory(1) associated with each cutting tool in order to store the data relating to the characteristics of the tool and the characteristics of the operations for adjusting the machine in order to use the tool, a reading element(2) for reading a data(12) in the memory, an element(3) for displaying a menu relating to the data, and a control element(4) for generating and transmitting control signals(6,7,8 ...

A device for controlling a machine for cutting blanks from a sheet material

System zur Steuerung einer Schneidpresse für blattförmige Materialien

Device for controlling a machine for cutting blanks from a sheet material

The machine controlled by the device comprises a set of cutting tools interchangeable in dependence on the blank to be cut, means adjustable in dependence on the jobs to be performed by each tool, and means for actuating the adjustable means. The control device comprises a memory (1) associated with each cutting tool in order to store the data relating to the characteristics of the tool and of the operations for adjusting the machine (5) in order to use the tool, reading means (2) for reading the data in the said memory, means (3) for displaying a menu relating to the data and control means (4) for generating and transmitting control signals (6, 7, 8) to the actuating means in dependence on the menu.

PYRIDYL OR PYRIMIDYL MTOR KINASE INHIBITORS

The invention relates to compounds or pharmaceutically acceptable salts thereof of formula (I): 9. A compound according to claim 1 , which is:[(5-{4-[(3S)-3-ethylmorpholin-4-yl]-6-(methanesulfonylmethyl)pyrimidin-2-yl}-1H-pyrrolo[3,2-b]pyridin-2-yl)methyl](methyl)amine;(S)-(5-(4-(3-ethylmorpholino)-6-((methylsulfonyl)methyl)pyrimidin-2-yl)-1H-pyrrolo[3,2-b]pyridin-2-yl)methanol;[(5-{4-[(3S)-3-ethylmorpholin-4-yl]-6-(4-methanesulfonyloxan-4-yl)pyrimidin-2-yl}-1H-pyrrolo[3,2-b]pyridin-2-yl)methyl](methyl)amine;(5-{4-[(3S)-3-ethylmorpholin-4-yl]-6-(4-methanesulfonyloxan-4-yl)pyrimidin-2-yl}-1H-pyrrolo[3,2-b]pyridin-2-yl)methanol;(5S)-5-ethyl-4-{2-[2-(hydroxymethyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]-6-(methanesulfonylmethyl)pyrimidin-4-yl}morpholin-3-one;{6-[(3S)-3-ethylmorpholin-4-yl]-2-{2-[(methylamino)methyl]-1H-pyrrolo[3,2-b]pyridin-5-yl}pyrimidin-4-yl}methanesulfonamide;(S)-1-(2-(3-ethyl-5-oxomorpholino)-6-(2-((methylamino)methyl)-1H-pyrrolo[3,2-b]pyridin-5-yl)pyridin-4-yl)-N,N-dimethylmethanesulfonamide;1-{6-[(3S)-3-ethylmorpholin-4-yl]-2-[2-(hydroxymethyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]pyrimidin-4-yl}-N,N-dimethylmethanesulfonamide;1-{6-[(3S)-3-ethylmorpholin-4-yl]-2-[2-(hydroxymethyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]pyrimidin-4-yl}-N-methylmethanesulfonamide;1-{6-[(3S)-3-ethylmorpholin-4-yl]-2-{2-methyl-1H-pyrrolo[3,2-b]pyridin-5-yl}pyrimidin-4-yl}-N-methylmethanesulfonamide;(3S)-3-ethyl-4-[6-(methanesulfonylmethyl)-2-{2-methyl-1H-pyrrolo[3,2-b]pyridin-5-yl}pyrimidin-4-yl]morpholine;(3S)-3-ethyl-4-[6-(4-methanesulfonyloxan-4-yl)-2-{2-methyl-1H-pyrrolo[3,2-b]pyridin-5-yl}pyrimidin-4-yl]morpholine;(5S)-5-ethyl-4-[6-(methanesulfonylmethyl)-2-{2-methyl-1H-pyrrolo[3,2-b]pyridin-5-yl}pyrimidin-4-yl]morpholin-3-one;(5S)-5-ethyl-4-(2-{2-ethyl-1H-pyrrolo[3,2-b]pyridin-5-yl}-6-(methanesulfonylmethyl)pyrimidin-4-yl)morpholin-3-one;1-{6-[(3S)-3-ethylmorpholin-4-yl]-2-{2-[(methylamino)methyl]-1H-pyrrolo[3,2-b]pyridin-5-yl}pyrimidin-4-yl}-N,N-dimethylmethanesulfonamide;(3S)-3- ...

Detection of passage of wheels or axles on single or dual traffic roadway

The traffic counter strip has a thickness (H) of between 4 and 11 mm, and has a cylindrical coaxial piezo-electric detector (1) of circular or oval cross section embedded horizontally. A shock-absorbing strip made of a rubber mousse (3) forms the two edges of the counter strip, along the long edges of the strip that lie perpendicular to the direction of the traffic. A thin metal strip (2) lies below the detector cable, and has a width of between 10 and 30 mm. The metal strip is embedded in a layer of non-rigid plastic, and gives good a rigidity to the counter strip in the transverse direction. The counter strip is attached to the road surface with an adhesive.

Device for detecting passage over a roadway, and its installation method

Device characterised in that it uses at least two sensors with piezo-electric effect (2) and an induction loop (1) per traffic route and that the sensors which are furthest away are arranged in the same incision as the strands which are perpendicular to the traffic of the induction loop (1). The sensors used can be of the piezo-electric, capacitive or optical fibre type.

DEVICE FOR DETECTING PASSAGE ON A PAVEMENT, AND ITS METHOD OF LAYING.

METHOD FOR MEASURING DYNAMIC LOAD GENERATED BY VEHICLES ON A PAVEMENT, DEVICES FOR ITS IMPLEMENTATION.

Method and device for measuring dynamic loads generated by vehicles on a road.

A device for controlling a machine for cutting blanks from a sheet material

The machine controlled by the device comprises a set of cutting tools interchangeable in dependence on the blank to be cut, means adjustable in dependence on the jobs to be performed by each tool, and means for actuating the adjustable means. The control device comprises a memory (1) associated with each cutting tool in order to store the data relating to the characteristics of the tool and of the operations for adjusting the machine (5) in order to use the tool, reading means (2) for reading the data in the said memory, means (3) for displaying a menu relating to the data and control means (4) for generating and transmitting control signals (6, 7, 8) to the actuating means in dependence on the menu.

INK JET PRINTING METHOD, INK JET PRINTING MACHINE, AND ANTI-DRYING DEVICE

Vacuum transport method and vacuum chamber for an inkjet printing machine, and inkjet printing machine

The present invention relates to a method for transporting cardboard sheet elements 12 in an inkjet printing machine 10 comprising a vacuum transport device 13 and at least one printing head 14, - during a pressing phase, a vacuum effect is applied through the vacuum transport device 13 to each cardboard sheet element 12 as it passes under a printing head 14; - during a shutoff phase, the vacuum effect is interrupted under any printing head 14 under which a gap separating two cardboard sheet elements 12, 12' passes. The invention also relates to a vacuum chamber 20 for implementing the method, comprising a shutoff device 21 for interrupting the vacuum effect, and to an inkjet printing machine 10 comprising such a vacuum chamber 20.

VACUUM TRANSPORT METHOD AND VACUUM CHAMBER FOR AN INK JET PRINTING MACHINE, AND INK JET PRINTING MACHINE

La présente invention un procédé de transport d'éléments en plaque 12 dans une machine d'impression 10 à jet d'encre comprenant un dispositif de transport vacuum 13 et au moins une tête d'impression 14, - lors d'une phase de plaquage, un effet vacuum est appliqué au travers du dispositif de transport vacuum 13 à chaque élément en plaque 12 lorsqu'il passe sous une tête d'impression 14; - lors d'une phase d'obturation, l'effet vacuum est interrompu sous toute tête d'impression 14 en dessous de laquelle passe un intervalle séparant deux éléments en plaque 12, 12'. L'invention concerne également une chambre à vacuum 20 pour la mise en œuvre du procédé, comprenant un dispositif obturateur 21 permettant d'interrompre l'effet vacuum, ainsi qu'une machine d'impression à jet d'encre 10 comprenant une telle chambre à vacuum 20).

Vacuum transport method and vacuum chamber for an inkjet printing machine, and inkjet printing machine

The present invention relates to a method for transporting cardboard sheet elements 12 in an inkjet printing machine 10 comprising a vacuum transport device 13 and at least one printing head 14, - during a pressing phase, a vacuum effect is applied through the vacuum transport device 13 to each cardboard sheet element 12 as it passes under a printing head 14; - during a shutoff phase, the vacuum effect is interrupted under any printing head 14 under which a gap separating two cardboard sheet elements 12, 12' passes. The invention also relates to a vacuum chamber 20 for implementing the method, comprising a shutoff device 21 for interrupting the vacuum effect, and to an inkjet printing machine 10 comprising such a vacuum chamber 20.

DEVICE FOR DETECTING THE PASSAGE OF VEHICLES ON A PIEZOELECTRIC FILM PAVEMENT

La présente invention concerne la réalisation d'un capteur constitué d'un empilage de rubans de film piézo-électrique 1 d'un ruban de film piézo-électrique 2, et d'un ruban conducteur 3 maintenu entre eux et enrobé dans un matériau souple type caoutchouc, connecté à une électronique par un câble à deux conducteurs. Le capteur peut être collé dans ou sur la chaussée ou maintenu mécaniquement. Application à la détection de véhicules circulant sur une chaussée. The present invention relates to the production of a sensor consisting of a stack of ribbons of piezoelectric film 1 of a ribbon of piezoelectric film 2, and of a conductive tape 3 held together and coated in a flexible material. rubber type, connected to electronics by a two-conductor cable. The sensor can be stuck in or on the road or mechanically held. Application to the detection of vehicles traveling on a roadway.

Valve doseuse avec chambre de dosage améliorée

Valve doseuse de distribution de produit fluide, comportant un corps de valve (10) contenant une chambre de dosage (20), ladite chambre de dosage (20) étant définie par un insert de chambre (40) et deux joints annulaires, un joint de soupape (21) et un joint de chambre (22), ledit insert de chambre (40) comportant une paroi cylindrique (49), un bord supérieur (41) coopérant avec ledit joint de soupape (21) et un bord inférieur (43) coopérant avec ledit joint de chambre (22), une soupape (30) coulissant axialement dans ledit corps de valve (10) entre une position de repos et une position de distribution, pour sélectivement distribuer le contenu de ladite chambre de dosage (20), ladite soupape (30) étant sollicitée vers sa position de repos par un ressort (8) coopérant d'une part avec ledit corps de valve (10) et d'autre part avec ladite soupape (30), ladite paroi cylindrique (49) dudit insert de chambre (40) comportant au moins une ouverture (48) reliant ladite chambre de dosage (20) à un volume externe disposé à l'extérieur dudit insert de chambre (40), entre ledit corps de valve (10) et ladite paroi cylindrique (49). « figure pour l’abrégé : figure 2 »

Inibidores de piridila ou pirimidila da quinase mtor

inibidores de piridila ou pirimidila da quinase mtor. a invenção se refere aos compostos ou sais farmaceuticamente aceitáveis destes de fórmula (i): (i) em que r1, r2, r3, r4, r4' e r5 são conforme definidos na descrição e nas reivindicações; e aos compostos ou sais farmaceuticamente aceitáveis destes de fórmulas (ii), (iia), (iib), (iic) e (iii) tendo atividade de inibidor da quinase mtor. a invenção também se refere às composições farmacêuticas que incluem um composto de fórmula (i), (ii), (iia), (iib), (iic) ou (iii) ou um sal farmaceuticamente aceitável deste, e ao uso de um composto de fórmula (i), (ii), (iia), (iib), (iic) ou (iii), ou um sal farmaceuticamente aceitável deste, em terapia, incluindo no tratamento de uma doença ou condição para a qual seja indicada um atividade de inibidor da quinase mtor e, em particular, o tratamento da fibrose pulmonar idiopática.

Pyridyl or pyrimidyl mtor kinase inhibitors

The invention relates to compounds or pharmaceutically acceptable salts thereof of formula (I): (I) wherein R1, R2, R3, R4, R4' and R5 are as defined in the description and claims; and compounds or pharmaceutically acceptable salts thereof of formulas (II), (IIa), (IIb), (IIc), and (III) having mTOR kinase inhibitor activity. The invention also relates to pharmaceutical compositions which include a compound of formula (I), (II), (IIa), (IIb), (IIc), or (III) or a pharmaceutically acceptable salt thereof, and to the use of a compound of formula (I), (II), (IIa), (IIb), (IIc), or (III), or a pharmaceutically acceptable salt thereof in therapy, including in the treatment of a disease or condition for which an mTOR kinase inhibitor activity is indicated, and in particular the treatment of idiopathic pulmonary fibrosis.

Compuesto de 1h-pirrolo[3,2-b]piridin-5-ilo, composición farmacéutica que lo comprende y su uso para fabricar un medicamento

Un compuesto de 1H-pirrolo[3,2-b]piridin-5-ilo de la fórmula (1), en donde: X es O ó NH; R¹ es alquilo C₁₋₃, CH₂NH-alquilo C₁₋₃, o alquil C₁₋₃-OH; R² es alquilo C₁₋₃, N(H)alquilo C₁₋₃, N(alquilo C₁₋₃)₂ o NH₂; R³ es CH₂ o C=O; R⁴ y R⁴’ son H, o R⁴ y R⁴’ se combinan para formar un heterocicloalquileno de 5 ó 6 miembros que está no sustituido o sustituido con alquilo C₁₋₃; y R⁵ es CH o N; en donde R⁵ es CH y R¹ es alquilo C₂₋₃, CH₂NH-alquilo C₁₋₃, o CH₂OH, entonces R³ no es CH₂; o una de sus sales farmacéuticamente aceptables. Se describen composiciones farmacéuticas que incluyen un compuesto de fórmula (1) o una de sus sales farmacéuticamente aceptables, y al uso de un compuesto de fórmula (1) o una de sus sales farmacéuticamente aceptables para la fabricación de un medicamento para el tratamiento de una enfermedad o condición para la que se indica una actividad inhibidora de la quinasa mTOR y, en particular, el tratamiento de la fibrosis pulmonar idiopática.

Pyridyl or pyrimidyl mtor kinase inhibitors

The invention relates to compounds or pharmaceutically acceptable salts thereof of formula (I): (I) wherein R 1 , R 2 , R 3 , R 4 , R 4' and R 5 are as defined in the description and claims; and compounds or pharmaceutically acceptable salts thereof of formulas (II), (IIa), (IIb), (IIc), and (III) having mTOR kinase inhibitor activity. The invention also relates to pharmaceutical compositions which include a compound of formula (I), (II), (IIa), (IIb), (IIc), or (III) or a pharmaceutically acceptable salt thereof, and to the use of a compound of formula (I), (II), (IIa), (IIb), (IIc), or (III), or a pharmaceutically acceptable salt thereof in therapy, including in the treatment of a disease or condition for which an mTOR kinase inhibitor activity is indicated, and in particular the treatment of idiopathic pulmonary fibrosis.

System zur steuerung einer schneidpresse für blattförmige materialien