ASARUM TOTAL POLYSACCHARIDES EXTRACT HAVING ANTITUSSIVE ACTIVITY AND EXTRACTION METHOD AND USE THEREOF

The present invention discloses an Asarum total polysaccharide extract with antitussive activity, an extraction method thereof and an application in the preparation of a medicine for preventing and treating coughs. The present invention proves that the Asarum total polysaccharide extract has a significant effect of suppressing cough for the first time through a large number of pharmacodynamic tests, has the therapeutic effect approximate to codeine, has the effect of prolonging the cough latent period better than codeine, and also finds that the total Asarum polysaccharide extract has the effects of reducing the cough sensitivity and suppressing the airway inflammation for the first time, has excellent preventive and therapeutic effects on various types of coughs, and can be used for preparing the medicines for preventing and treating cough-related diseases.

APPLICATION OF FRUCTUS SCHISANDRAE TOTAL POLYSACCHARIDES IN PREPARATOIN OF MEDICINE OR NUTRACEUTICALS USED FOR TREATING COUGHING

The present invention relates to a new application of Fructus schisandrae total polysaccharides in preparation of medicine or nutraceuticals for treating coughing, and more specifically to a new application of Fructus schisandrae total polysaccharides in preparation of medicine or nutraceuticals for preventing and relieving coughing and eliminating airway inflammation. Experiments demonstrate that the Fructus schisandrae total polysaccharides can remarkably reduce the coughing times of a guinea pig with increased cough sensitivity induced by cigarette smoke and an acute cough guinea pig induced by citric acid smoke, prolong the latent period of cough, and significantly reduce the airway inflammation of the guinea pig with increased cough susceptibility induced by cigarette smoke, so that the Fructus schisandrae total polysaccharides can be used for preparing drugs for preventing cough, relieving cough and eliminating airway inflammation. 1. An application of Fructus schisandrae total polysaccharides in preparation of medicine or nutraceuticals used for treating coughing , characterized in that the medicine or nutraceuticals are used for treating acute cough , sub-acute cough or chronic cough; and the Fructus schisandrae total polysaccharides are prepared through the following steps: pulverizing Fructus schisandrae , degreasing the pulverized Fructus schisandrae with petroleum ether , decocting the degreased Fructus schisandrae for three times by using 8 times water , concentrating obtained decocted liquid , precipitating the concentrated solution by using 80% ethanol , filtering , performing deproteinization through a precipitation enzymatic method , decoloring by using active carbon , repeatedly washing by using 80% ethanol , and then drying to obtain the Fructus schisandrae total polysaccharides , and the content of polysaccharides in the Fructus schisandrae total polysaccharides is 89% through test on the basis of D-glucose.2. The application according to claim 1 ...

Application of asarum total polysaccharides in preparation of medicine for treating cough

The present invention discloses an Asarum total polysaccharide extract with antitussive activity, an extraction method thereof and an application in the preparation of a medicine for preventing and treating coughs. The present invention proves that the Asarum total polysaccharide extract has a significant effect of suppressing cough for the first time through a large number of pharmacodynamic tests, has the therapeutic effect approximate to codeine, has the effect of prolonging the cough latent period better than codeine, and also finds that the total Asarum polysaccharide extract has the effects of reducing the cough sensitivity and suppressing the airway inflammation for the first time, has excellent preventive and therapeutic effects on various types of coughs, and can be used for preparing the medicines for preventing and treating cough-related diseases.

Application of fructus schisandrae total polysaccharides in preparation of medicine or nutraceuticals used for treating coughing

Asarum total polysaccharides extract having antitussive activity and extraction method and use thereof

Application of fructus schisandrae total polysaccharides in preparatoin of medicine or nutraceuticals used for treating coughing

The present invention relates to a new application of Fructus schisandrae total polysaccharides in preparation of medicine or nutraceuticals for treating coughing, and more specifically to a new application of Fructus schisandrae total polysaccharides in preparation of medicine or nutraceuticals for preventing and relieving coughing and eliminating airway inflammation. Experiments demonstrate that the Fructus schisandrae total polysaccharides can remarkably reduce the coughing times of a guinea pig with increased cough sensitivity induced by cigarette smoke and an acute cough guinea pig induced by citric acid smoke, prolong the latent period of cough, and significantly reduce the airway inflammation of the guinea pig with increased cough susceptibility induced by cigarette smoke, so that the Fructus schisandrae total polysaccharides can be used for preparing drugs for preventing cough, relieving cough and eliminating airway inflammation.