28-10-2021 дата публикации
Номер: US20210330981A1
Принадлежит:
A medical apparatus for a patient comprises an implantable system. The implantable system comprises a first implantable device comprising: at least one implantable functional element configured to deliver stimulation energy to tissue of the patient; and an implantable controller configured to provide a stimulation waveform to the at least one implantable functional element, the stimulation waveform comprising one or more stimulation parameters. The apparatus is configured to randomly vary at least one of the one or more stimulation parameters. Methods of providing stimulation energy with randomly varying stimulation parameters are also provided. 1. A method for treating a patient , the method comprising:delivering therapeutic stimulation energy to a tissue of the patient, the therapeutic stimulation energy being based on a therapeutic stimulation waveform,wherein the therapeutic stimulation waveform comprises bursts of trains of pulses, each train having a train-on period from a beginning of a first pulse of said train to an end of a last pulse of said train, wherein there is a train-off quiescent period between an end of one train and a beginning of a next train, and', 'each burst having a burst-on period from a beginning of a first pulse of a first train of said burst to an end of a last pulse of a last train of said burst, wherein there is a burst-off quiescent period between an end of one burst and a beginning of a next burst, and, 'wherein each train comprises a series of pulses and each burst comprises a series of trains,'}wherein the therapeutic stimulation waveform comprises a plurality of waveform parameters including the train-on period, the train-off quiescent period, the train-off quiescent period, the burst-on period, and the burst-off quiescent period, said waveform parameters being selected to effect treatment of the patient.2. The method according to claim 1 , wherein the train-on period is between 1 μsec and 100 msec.3. The method according to claim ...
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