24-03-2010 дата публикации
Номер: CN0101676269A
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The invention relates to a functionalized united imidazole derivative and a synthesizing method thereof. More particularly, the functionalized united imidazole derivative is a derivative of 1, 1-dsubstituted united imidazole acidamide, united imidazole carboxylic acid or united imidazole amine shown by formula I, wherein n is equal to 1 or 2; and X is acylamino, carboxyl or amido. A method for preparing the united imidazole acidamide comprises: taking united imidazole as raw material and N, N-dimethyl formamide as solvent; and leading the united imidazole and the N, N-dimethyl formamide to have Michael addition or nucleophilic substitution reaction together with acrylamide and chloroacetamide under the alkali condition, and obtaining the united imidazole acidamide; a method for preparing the united imidazole carboxylic acid comprises: taking united imidazole nitriles derivative as raw material, and having hydrolysis reaction under the acidic condition to obtain the united imidazole carboxylic ...
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