27-11-2014 дата публикации
Номер: US20140349386A1
Принадлежит:
A nucleic acid extraction device, which can realize automation, ultra-miniaturization and super-high speed in the nucleic acid extraction reaction, has no limitation to the type of biological specimens that can be used, such as sputum, blood, cells, urine, saliva, tissues, etc., minimize the used amount of the sample solution, and also maintain and/or improve the nucleic acid extraction efficiency with reliability. 1. A device for extracting a nucleic acid from a biological specimen , the device comprising:a substrate; an inlet portion,', 'an outlet portion,', 'a channel connecting the inlet portion and the outlet portion, and', 'a filter disposed in the channel and having a porous structure;, 'a microfluidic chip comprising,'}a chip support disposed on one side of the substrate and including a chip receiving portion defining a space so that the chip receiving portion houses the microfluidic chip therein; anda heater disposed in the substrate and configured to apply heat to a part of the microfluidic chip.2. The device as claimed in claim 1 , wherein the chip receiving portion has a shape of a plate with a horizontal surface in close contact with one side of the microfluidic chip claim 1 ,wherein the heater is a contact plate type heating block, andwherein the heater transfers the heat to the microfluidic chip by a surface contact.3. The device as claimed in claim 1 , further comprising:a chip cover being arranged on one side of the chip support and having a horizontal surface in close contact with another side of the microfluidic chip.4. The device as claimed in claim 1 , further comprising:a fluid control module configured to control the flow of a reactant solution in the microfluidic chip.5. The device as claimed in claim 1 , further comprising:a heat control unit connected to the heater to control an amount of heat applied to a reactant solution in the microfluidic chip.6. The device as claimed in claim 1 , wherein the channel includes a first channel region ...
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