Reinforced graft prosthesis

A medical device, such as a prosthesis, and method of forming the same are disclosed. The medical device includes a cover material and a reinforcement element, and may include a stent frame structure. The reinforcement element includes a plurality of bends disposed about a pattern axis. The pattern axis is arranged helically along the cover material.

MEDICAL DEVICES FOR CONTROLLED DRUG RELEASE

A medical device for controlling a release of bioactive agents to a body of patient. The medical device includes a support structure and a coating disposed at least partially covering the support structure. The coating includes a biodegradable outer and inner layer. First beads are disposed between the layers. A therapeutically effective amount of a first bioactive agent is disposed within pores of the first beads. Second beads are disposed between the support structure and the inner layer. A therapeutically effective amount of a second bioactive agent is disposed within the pores of the second beads. The first beads are releasable in response to at least partial biodegradation of the outer layer, and the second beads are releasable after the first beads in response to at least partial biodegradation of the inner layer. The coating may include a nonwoven matrix. 1. A medical device for controlling a release of bioactive agents , the medical device comprising:a support structure configured and sized to be used within a body of a human or an animal;a coating at least partially covering an exterior of the support structure, the coating comprising:a biodegradable outer layer;to a biodegradable inner layer coaxially disposed inward relative to the biodegradable outer layer;a plurality of first beads disposed between the outer and inner layers, each of the first beads comprising a biocompatible porous body having a plurality of pores, each of the first beads including a bead coating operable for binding to a is wall of the body, wherein a therapeutically effective amount of a first bioactive agent is disposed within the pores of the first beads; anda plurality of second beads disposed between the support structure and the inner layer, each of the second beads comprising a biocompatible porous body having a plurality of pores, wherein a therapeutically effective amount of a second bioactive agent is disposed within the pores of the second beads,wherein the first beads are ...

Expandable medical device and method of use thereof

The present invention relates generally to expandable medical devices including a light-activated shape-memory polymer. In certain embodiments, the devices include, for example, balloon catheters, used to treat narrowed or obstructed portions of a body vessel, and retrieval devices, used to remove obstructions from a body vessel. Certain aspects of the invention relate to methods of manufacturing and using such devices.

SYSTEMS AND METHODS FOR CONTROLLED RELEASE OF STENT BARBS

The present embodiments provide a system for controlled release of a portion of a stent. In one example, the system comprises a stent having proximal and distal regions, and a first barb coupled to the stent. A trigger wire restrains a portion of the stent in a delivery state. The system further comprises a barb release wire having proximal and distal regions, and an engagement region disposed therebetween. The distal region of the barb release wire is coupled to the trigger wire, and the engagement region of the barb release wire is disposed around a portion of the first barb to restrain the first barb in the delivery state. In one example, distal retraction of the trigger wire causes a simultaneous distal retraction of the barb release wire. 1. A system for controlled release of a portion of a stent , the system comprising:a stent having proximal and distal regions;a first barb coupled to the stent;a trigger wire that restrains a portion of the stent in a delivery state; anda barb release wire having proximal and distal regions, and an engagement region disposed therebetween,wherein the distal region of the barb release wire is coupled to the trigger wire, and the engagement region of the barb release wire is disposed around a portion of the first barb to restrain the first barb in the delivery state,wherein distal retraction of the trigger wire causes a simultaneous distal retraction of the barb release wire.2. The system of claim 1 , wherein the barb release wire spans a shorter axial length than the trigger wire.3. The system of claim 1 , wherein the trigger wire restrains at least one proximal apex of the stent in the delivery state.4. The system of claim 3 , wherein the at least one proximal apex comprises an end region having a bore formed therein claim 3 , wherein the trigger wire extends through the bore in the delivery state.5. The system of claim 1 , wherein the first barb comprises a proximal segment having a base region coupled to the stent claim 1 , a ...

Data storage on implantable magnetizable fabric

The disclosure is directed to a system, device and method for data storage on implantable magnetizable fabric. The system includes implantable magnetizable fabric coupled to a graft segment of a prosthesis for being delivered into a body of a subject. The system includes information written on the implantable magnetizable fabric. The system further includes a magnetic detection device capable of, after the prosthesis is delivered into the body of the subject, detecting the implantable magnetizable fabric and accessing at least a portion of the information.

HOMOGENOUS ILLUMINATION OF FIBER OPTIC DEVICES

A catheter system for trans-illumination of a surgical area may include a catheter tube having a distal end and a proximal end. The proximal end may include a non-transparent portion and the distal end may include a transparent fiber optic portion. The transparent fiber optic portion may include a fiber optic capable of transmitting light, a plurality of grain indentations having a depth below the surface of the fiber optic portion that communicate light through the outer surface of the fiber optic portion, and reflective coatings. The plurality of grain indentations may increase in size or density, or increase by both size and density, along the length of the fiber optic to provide for a homogenous scattering of light along the fiber optic. The first and second reflective coatings may absorb or reflect light and be shaped to further facilitate homogeneous light scattering along the fiber optic.

RADIOPACITY MODULATED RADIOPAQUE MARKER AND STENT GRAFT USING SAME

In one aspect, a radiopaque marker for a medical implant, such as a stent graft for aortic aneurism repair, includes a first radiopaque component connected to a second radiopaque component by a connection. The first radiopaque component includes a non-biodegradable radiopaque body. The radiopaque marker has a first configuration and a second configuration that differ from one another in at least one of volume and shape such that the first and second configurations produce different radiographic images. This change in radiopacity can provide useful information to a surgeon in the event that reintervention becomes necessary. 1. A radiopacity modulated radiopaque marker for a medical implant comprising:a first radiopaque component;a second radiopaque component connected to the first radiopaque component by a connection;wherein the first radiopaque component includes a non-biodegradable radiopaque body;wherein the radiopaque marker has first configuration and a second configuration that differs from the first configuration in at least one of volume and shape such that the first and second configurations produce different radiographic images.2. The radiopaque marker of wherein the non-biodegradable radiopaque body is an integral block of metallic material.3. The radiopaque marker of wherein the second radiopaque component includes a biodegradable coating covering at least a portion of the integral block of metallic material.4. The radiopaque marker of wherein at least one of the first radiopaque component claim 1 , the second radiopaque component and the connection define a hole therethrough sized to receive at least one of a suture and a stent strut to facilitate attachment to a medical implant.5. The radiopaque marker of wherein the integral block of metallic material is a first integral block of metallic material;the second radiopaque component includes a second integral block of metallic material; andthe connection changes shape responsive to a stimulus.6. The ...

Stent deployment system with unwrapping deployment constraint

A stent delivery system includes a self expanding stent positioned about a distal support segment of a catheter, which includes a proximal segment. A constraint has a wrapped configuration, which has a hollow elongated shape, and an unwrapped configuration, which is a continuous length of a strip. The stent is in contact with, and held in a compressed state by, the constraint in the wrapped configuration, and the stent is in an expanded state out of contact with the constraint in the unwrapped configuration. The constraint may move from the wrapped configuration toward the unwrapped configuration responsive to tension in a control line connected to one end of the strip.

GRAFT MATERIAL AND METHOD OF USE THEREOF

The present disclosure relates to woven and knitted fabrics including boron nitride nanotubes and to methods of manufacturing and using such materials. In one embodiment, these materials are incorporated into implantable medical devices such as stent graft devices and the like. 1. A fabric comprising a knitted or woven textile material and a plurality of boron nitride nanotubes , wherein the boron nitride nanotubes are present in a matrix between strands of the knitted or woven textile material or in the strands of the knitted or woven textile material.2. The fabric of claim 1 , wherein the knitted or woven textile material is a woven textile material.3. The fabric of claim 1 , wherein the knitted or woven textile material is a knitted textile material.4. The fabric of claim 1 , wherein the textile material comprises a material selected from the group consisting of a polyester claim 1 , polyethylene terephthalate claim 1 , a fluorinated polymer claim 1 , polytetrafluoroethylene (PTFE) claim 1 , expanded PTFE claim 1 , a polyurethane claim 1 , polyethylene claim 1 , polypropylene claim 1 , polyaram id claim 1 , polyacrylonitrile claim 1 , nylon and cellulose.5. The fabric of claim 4 , wherein the textile material comprises polyethylene terephthalate.6. The fabric of claim 1 , wherein the boron nitride nanotubes are present in the strands of the knitted or woven textile material.7. The fabric of claim 6 , wherein the strands comprise a plurality of filaments of the textile material claim 6 , wherein the filaments are twisted and wherein the boron nitride nanotubes are continuously integrated along the filaments.8. The fabric of claim 6 , wherein the strands comprise a plurality of filaments of the textile material claim 6 , wherein the filaments are twisted and wherein the boron nitride nanotubes are discontinuously integrated along the filaments.9. The fabric of claim 6 , wherein the strands comprise a plurality of twisted filaments of the textile material and the ...

EXPANDABLE MEDICAL DEVICE AND METHOD OF USE THEREOF

The present invention relates generally to expandable medical devices including a light-activated shape-memory polymer. In certain embodiments, the devices include, for example, balloon catheters, used to treat narrowed or obstructed portions of a body vessel, and retrieval devices, used to remove obstructions from a body vessel. Certain aspects of the invention relate to methods of manufacturing and using such devices. 1. An implantable medical device comprising:an elongated catheter extending from a distal end to a proximal end and comprising a first lumen;a plurality of optical fibers extending in the first lumen from the proximal end to the distal end;an expandable body attaching to a distal end of the elongated catheter, wherein the expandable body comprises an light-sensitive polymeric material, andwherein a distal end of the plurality of optical fibers is optically coupled to the light-sensitive polymeric material.2. The implantable medical device of claim 1 , further comprising a light source optically coupled to a proximal end of the plurality of optical fibers.3. The implantable medical device of claim 2 , wherein the light source is selected from the group consisting of a laser and a light emitting diode.4. The implantable medical device of claim 1 , the expandable body having an expanded configuration and a collapsed configuration claim 1 , wherein the expandable body transitions from the collapsed configuration to the expanded configuration upon optical illumination of the light-sensitive polymeric material.5. The implantable medical device of claim 1 , wherein the light-sensitive polymeric material comprises a polymer coupled to a material selected from the group consisting of cinnamic acid and cinnamylidene acetic acid.6. The implantable medical device of claim 1 , wherein the expandable body comprises a hollow tubular body having a tubular wall comprising the light-sensitive polymeric material and defining an internal lumen.7. The implantable medical ...

BIFURCATED STENT GRAFT WITH HEMODYNAMIC BLOOD FLOW DIVIDING WALL

A bifurcated stent graft includes a stent graft body that defines exactly one main body opening and at least two exit openings. The stent graft body includes at least one stent attached to a graft fabric material, and includes a dividing wall that divides a combined flow path, into a first flow path and a second flow path that each terminate at one of the respective exit openings. The dividing wall includes a thickness profile that terminates at a leading edge radius that extends across a width of the combined flow path. 1. A bifurcated stent graft comprising:a stent graft body defining exactly one main body opening and at least two exit openings;the stent graft body includes at least one stent attached to a graft fabric material, a bifurcation and a dividing wall that divides a combined flow path into a first flow path and a second flow path that each terminate at one of the respective exit openings; andthe dividing wall includes a thickness profile that terminates at a leading edge radius that extends across a width of the combined flow path.2. The bifurcated stent graft of wherein the thickness profile of the dividing wall includes a tapered segment that begins as a tangent to the leading edge radius.3. The bifurcated stent graft of wherein the tapered segment has a length greater than double the leading edge radius.4. The bifurcated stent graft of wherein a taper angle of the tapered segment is a function of the leading edge radius and the length of the tapered segment.5. The bifurcated stent graft of wherein the tapered segment thins toward the leading edge radius.6. The bifurcated stent graft of wherein the tapered segment thickens toward the leading edge radius.7. The bifurcated stent graft of wherein one of the two exit openings is further from the bifurcation than an other one of the two exit openings.8. The bifurcated stent graft of wherein the leading edge radius is further from the bifurcation than the main body opening.9. The bifurcated stent graft of ...

DEPLOYING A BALLOON EXPANDABLE STENT TO INDUCE SPIRAL FLOW

A balloon expanded stent delivery system includes an inflation constraint, such as a wire, spirally wound about the longitudinal axis in contact with a balloon and attached to an underlying catheter. A balloon expanded stent is mounted about the balloon and the inflation constraint. The delivery system has a predeployment configuration with the balloon deflated and the stent unexpanded. The system has a deployment configuration in which the inflation constraint constrains the inflated balloon to a spiral shape, the stent is expanded and in contact with the balloon, and the stent has a flow directing surface with a spiral contour that matches the spiral shape of the balloon. In a postdeployment configuration, the stent retains the flow directing surface with the spiral contour. 1. A balloon expanded stent delivery system comprising:a catheter with a longitudinal axis;a balloon mounted about the catheter;an inflation constraint spirally wound about the longitudinal axis in contact with the balloon and being attached to the catheter;a balloon expanded stent mounted about the balloon and the inflation constraint;the delivery system having a predeployment configuration characterized by the balloon being deflated, and the stent is unexpanded and in contact with the balloon;the delivery system having a deployment configuration characterized by the balloon being inflated, the inflation constraint constrains the inflated balloon to a spiral shape, the stent is expanded and in contact with the balloon, and the stent has a flow directing surface with a spiral contour that matches the spiral shape of the balloon; andthe delivery system having a postdeployment configuration characterized by the balloon being deflated and out of contact with the stent, and the stent retains the flow directing surface with the spiral contour.2. The delivery system of wherein the inflation constraint includes a wire spirally wound about the balloon and constraining the balloon to the spiral shape ...

BIFURCATED STENT GRAFT WITH HEMODYNAMIC BLOOD FLOW DIVIDING WALL

A bifurcated stent graft includes a stent graft body that defines exactly one main body opening and two exit openings. The stent graft body includes at least one stent attached to a graft fabric material, and includes a dividing wall that divides a combined flow path, into a first flow path and a second flow path that each terminate at one of the respective exit openings. The dividing wall includes a thickness profile that is equal to or thinner than a wall thickness of the graft fabric material, terminates a leading rounded surface, and extends across a width of the combined flow path. 1. A bifurcated stent graft comprising:a stent graft body defining exactly one main body opening and two exit openings;the stent graft body includes at least one stent attached to a graft fabric material, a bifurcation, and a dividing wall that divides a combined flow path into a first flow path and a second flow path that each terminate at one of the respective exit openings; andthe dividing wall includes a thickness profile that is equal to or thinner than a wall thickness of the graft fabric material, terminates at a leading rounded surface, and extends across a width of the combined flow path.2. The bifurcated stent graft of wherein the dividing wall is permeable to blood passing through the dividing wall from one of the first and second flow paths to an other one of the first and second flow paths.3. The bifurcated stent graft of wherein a permeability of the dividing wall to blood changes from the leading round surface toward the bifurcation.4. The bifurcated stent graft of wherein the permeability of the dividing wall decreases with a distance from the leading round surface toward the bifurcation.5. The bifurcated stent graft of wherein the dividing wall has a continuum of decreasing permeability in a direction from the leading rounded surface toward the bifurcation.6. The bifurcated stent graft of wherein the stent graft body includes a first leg and a second leg that each ...

SHAPE CONTROLLED BALLOON CATHETER

A shape controlled balloon catheter includes the balloon mounted about a catheter. A wire is spirally wound about the balloon and includes a manipulation segment extending along a centerline of the catheter away from the balloon. A position of the wire on an outer surface of the balloon changes responsive to movement of the manipulation segment relative to the catheter along the centerline. The balloon has a continuum of different inflated shapes corresponding to a continuum of different positions of the manipulation segment of the wire relative to the catheter. 1. A shape controlled balloon catheter comprisinga catheter;a balloon mounted about the catheter;a wire spirally wound about the balloon and including a manipulation segment extending along a centerline of the catheter away from the balloon;wherein a position of the wire on an outer surface of the balloon changes responsive to a movement of the manipulation segment relative to the catheter along the centerline;the balloon having a continuum of different inflated shapes corresponding to a continuum of different positions of the manipulation segment relative to the catheter along the centerline.2. The shape controlled balloon catheter of wherein a distal end of the wire is attached to the catheter distally of the balloon.3. The shape controlled balloon catheter of wherein a distal end of the wire is moved along an outer surface of the balloon responsive to the movement of the manipulation segment relative to the catheter along the centerline.4. The shape controlled balloon catheter of wherein the wire is a first wire; anda second wire spirally wound about the balloon and including a manipulation segment extending along the centerline away from the balloon.5. The shape controlled balloon catheter of wherein the second wire is wound in an opposite direction about the balloon than the first wire.6. The shape controlled balloon catheter of wherein the manipulation segment enters through a side port of the catheter ...

GRAFT MATERIAL AND METHOD OF USE THEREOF

The present disclosure relates to a graft material including a reinforced layer and to implantable medical devices including such a graft material. The invention also relates to methods of using and manufacturing such graft materials and devices. In one embodiment the implantable medical device is a stent graft. 1. A stent graft comprising:an expandable stent having a luminal and an abluminal surface; anda graft disposed on at least one of the luminal and the abluminal surface;wherein the graft comprises a first layer comprising fibers of a supramolecular polymer-colloidal hydrogel.2. The stent graft of claim 1 , wherein the graft further comprises a second layer comprising electro-spun polytetrafluoroethylene or expanded polytetrafluoroethylene claim 1 , wherein the second layer is disposed on the first layer.3. The stent graft of claim 2 , wherein the graft further comprises a third layer comprising electro-spun polytetrafluoroethylene or expanded polytetrafluoroethylene claim 2 , wherein the first layer is disposed between the second layer and the third layer.4. The stent-graft of claim 1 , wherein the fibers of a supramolecular polymer-colloidal hydrogel are woven claim 1 , knitted or braided.5. The stent-graft of claim 1 , wherein the fibers of a supramolecular polymer-colloidal hydrogel are imbedded in a polyurethane.6. The stent graft of claim 1 , wherein the supramolecular polymer-colloidal hydrogel comprises methyl viologen-functionalized polymer-grafted silica nanoparticles claim 1 , a semicrystalline polymer in the form of a hydroxyethyl cellulose derivative and cucurbit[8]uril claim 1 , wherein the semicrystalline polymer and the methyl viologen-functionalized polymer-grafted silica nanoparticles are cross-linked by the cucurbit[8]uril.7. The stent graft of claim 6 , wherein hydroxyethyl cellulose derivative is naphthalene isocyanate functionalized hydroxyethylcellulose.8. The stent graft of claim 1 , wherein the expandable stent comprises a plurality of ...

MULTI-STAGE BALLOON CATHETER, AND METHOD OF OPERATING SAME IN A CURVED PASSAGEWAY

A multi-stage balloon catheter has a deflated state, a first inflation state at a first pressure and a second inflation state at a higher fluid pressure. In the first inflation state, the multi-stage balloon has a plurality of bulb segments separated by waist hoops that allow the multi-stage balloon to conform to match the curvature of a passageway. When pressure is increased in the multi-stage balloon from the first inflation state to the second inflation state, the waist locations expand either by breaking or stretching the waist restraints or by overcoming expansion resistance incorporated into the balloon material at the waist locations. The multi-stage balloon catheter may be used to implant a stent in a manner to conform and match a curved passageway rather than tending to straighten the passageway. 1. A multistage balloon catheter comprising:a catheter that defines an inflation lumen and a centerline;a multistage balloon mounted on the catheter and having an interior fluidly connected to the inflation lumen;a plurality of waist hoops at respective waist locations of the multistage balloon, and each adjacent pair of waist hoops being separated by a bulb segment of the multistage balloon;the multistage balloon having a deflated state, a first inflation state and a second inflation state;the first inflation state being characterized by a first fluid pressure in the multistage balloon, hoop tension in the waist hoops holding the waist locations of the multistage balloon against expansion, the bulb segments having an expanded diameter greater than a waist diameter, and each adjacent pair of the bulb segments being pivoted with respect to each other about a pivot axis that is perpendicular to the centerline and intersects the waist hoop between the pair of adjacent bulb segments;the second inflation state being characterized by a second fluid pressure that is greater than the first fluid pressure, the waist locations are expanded to an enlarged diameter greater ...

MULTI-STAGE BALLOON CATHETER, AND METHOD OF OPERATING SAME IN A CURVED PASSAGEWAY

A multi-stage balloon catheter has a deflated state, a first inflation state at a first pressure and a second inflation state at a higher fluid pressure. In the first inflation state, the multi-stage balloon has a plurality of bulb segments separated by waist hoops that allow the multi-stage balloon to conform to match the curvature of a passageway. When pressure is increased in the multi-stage balloon from the first inflation state to the second inflation state, the waist locations expand either by breaking or stretching the waist restraints or by overcoming expansion resistance incorporated into the balloon material at the waist locations. The multi-stage balloon catheter may be used to implant a stent in a manner to conform and match a curved passageway rather than tending to straighten the passageway. 1. A multistage balloon catheter comprising:a catheter that defines an inflation lumen and a centerline;a multistage balloon mounted on the catheter and having an interior fluidly connected to the inflation lumen;a plurality of waist hoops at respective waist locations of the multistage balloon, and each adjacent pair of waist hoops being separated by a bulb segment of the multistage balloon;the multistage balloon having a deflated state, a first inflation state and a second inflation state;the first inflation state being characterized by a first fluid pressure in the multistage balloon, hoop tension in the waist hoops holding the waist locations of the multistage balloon against expansion, the bulb segments having an expanded diameter greater than a waist diameter, and each adjacent pair of the bulb segments being pivoted with respect to each other about a pivot axis that is perpendicular to the centerline and intersects the waist hoop between the pair of adjacent bulb segments; andthe second inflation state being characterized by a second fluid pressure that is greater than the first fluid pressure, the waist locations are expanded to an enlarged diameter greater ...

Self-healing graft material and method of use thereof

The present disclosure relates to a graft material including a self-healing polymer layer and to implantable medical devices including such a graft material. The invention also relates to methods of using and manufacturing such graft materials and devices. In one embodiment, the implantable medical device is a stent graft.

DEVICES INCORPORATING A MAGNET GUIDED FLEXIBLE REGION AND METHODS OF USE THEREOF

One aspect of the present invention relates generally to the field of medical devices, and more particularly, to a medical device including an elongated flexible region. In one embodiment, a magnetic assembly is coupled to a surface of the elongated flexible region and provides a stabilization force to maintain the elongated flexible region in a preferred configuration. In one embodiment, the flexible region is a region having a stacked coil configuration and a straightened configuration. 1. A medical device comprising:an elongated flexible body having an axis of elongation, the elongated flexible body having a stacked coil configuration and a straightened configuration,a magnetic assembly coupled a surface of the elongated flexible body and having a polarity profile providing a stabilization force to maintain the elongated flexible body in the stacked coil configuration.2. The medical device of claim 1 , wherein the stacked coil configuration comprises at least two complete coils3. The medical device of claim 2 , wherein the stacked coil configuration comprises at least three complete coils.4. The medical device of claim 1 , wherein the medical device is selected from the group consisting of a stent claim 1 , an uretheral stent claim 1 , a coil claim 1 , a snare claim 1 , a wire guide and a catheter.5. The medical device of claim 4 , wherein the medical device is an uretheral stent.6. The medical device of claim 1 , wherein the magnetic assembly comprises a plurality of magnets claim 1 , each having a surface and a plurality of north and south poles aligned along the surface claim 1 , wherein the positioning and magnetic polarity profile of the plurality of magnets is such that they provide a stabilization magnetic force to maintain the elongated flexible body in the stacked coil configuration.7. The medical device of claim 1 , wherein the magnetic assembly comprises a plurality of magnets each comprising a linear arrangement of north and south poles claim 1 , ...

DEVICE FOR TRANSLATIONAL MOVEMENT THROUGH VESSELS

A device for insertion into a vessel and suitable for implementing translational movement through the vessel includes a flexible tube containing a translational actuator. Anchoring actuators are positioned along the length of the flexible tube and are configured to controllably expand against the inner wall of the vessel in coordination with extension and contraction of the translational actuator to effect translational movement. 1. An apparatus suitable for translational movement through an interior of a vessel , the apparatus comprising:a flexible tube having a first end and a second end;a first vessel wall grappling member positioned on an exterior of the flexible tube adjacent the first end;a second vessel wall grappling member positioned on the exterior of the flexible tube adjacent the second end;wherein the first and second wall grappling members are adapted to selectively expand to contact a vessel wall surrounding the flexible tube; andan actuation mechanism positioned along at least a portion of a length of the flexible tube, the actuation mechanism being configured to cooperate with the first and second vessel wall grappling members to effect movement of the flexible tube in at least one direction relative to the vessel wall.2. The apparatus of claim 1 , wherein the flexible tube defines a hollow passage extending from the first end to the second end.3. The apparatus of claim 1 , wherein the first vessel wall grappling member is configured to expand in response to an increase in a first fluid pressure claim 1 , and to contract in response to a decrease in the first fluid pressure.4. The apparatus of claim 1 , wherein the first vessel wall grappling member comprises a balloon.5. The apparatus of claim 3 , wherein the first vessel wall grappling member comprises a toroidal shape.6. The apparatus of claim 1 , wherein the actuation mechanism is configured to repeatedly extend the flexible tube to a first length along a longitudinal axis of the flexible tube ...

GRAFT PROSTHESIS WITH POCKET FOR MICROSYSTEM

A medical device, such as a prosthesis, may include a graft material and a pocket disposed along at least one of luminal and abluminal surfaces of the graft material. The pocket may include a pocket opening leading into an enclosed cavity. The enclosed cavity may be sized to receive at least a portion of a microsystem, and the pocket may be accessible in vivo for removal of the microsystem from the pocket. 1. An implantable medical device comprising:a tubular graft material having an abluminal surface and a luminal surface,a pocket disposed along at least one of the luminal and abluminal surfaces of the graft material, the pocket including a pocket opening leading into an enclosed cavity, the enclosed cavity of the pocket sized to receive at least a portion of a microsystem, wherein the pocket is accessible in vivo for removal of the microsystem from the pocket.2. The device of claim 1 , wherein the pocket is disposed along the luminal surface of the graft material.3. The device of claim 2 , wherein the pocket includes a lid having a base extended from or coupled to the graft material and a lid tip disposed downstream of the base claim 2 , the lid pivotable about the base between an open configuration and a closed configuration claim 2 , wherein the lid tip is removably attached to the graft material with a coupling device.4. The device of claim 3 , wherein the lid includes a reinforcement band.5. The device of claim 3 , wherein the coupling device includes a lid magnet and a rim magnet claim 3 , the lid magnet is coupled to the lid claim 3 , and the pocket magnet coupled to a pocket edge of the pocket claim 3 , the rim magnet configured to magnetically couple to the lid magnet when the lid is in the closed configuration.6. The device of claim 5 , wherein the lid magnet extends beyond an edge of the lid tip and includes a grasping feature accessible outside the lid.7. The device of claim 1 , wherein a reinforcement edge band is disposed about a pocket edge that ...

SELF-ADAPTING GRAFT FOR PATIENTS

In one example, a prosthesis comprises a generally tubular graft material having an inner and outer perimeter, and a plurality of pleats between the inner and outer perimeters in a first state. At least one stent is coupled to the graft material. At least one layer of biocompatible material is coupled to the graft material in the first state. One or more sections of the at least one layer biodegrade over a first period of time at a first biodegradable rate. At least one of the plurality of pleats of the graft material unfolds to permit radial expansion of the graft material after the first period of time, and the stent provides support for the radial expansion of the graft material. 1. A prosthesis comprising:a generally tubular graft material having an inner and outer perimeter, and a plurality of pleats between the inner and outer perimeters in a first state;at least one stent coupled to the graft material; andat least one layer of biocompatible material coupled to the graft material in the first state,wherein one or more sections of the at least one layer biodegrade over a first period of time at a first biodegradable rate,wherein at least one of the plurality of pleats of the graft material unfolds to permit radial expansion of the graft material after the first period of time, wherein the stent provides support for the radial expansion of the graft material.2. The prosthesis of claim 1 , wherein after a final period of time longer than the first period of time claim 1 , the at least one layer is substantially entirely biodegraded to define a maximally expanded state.3. The prosthesis of claim 1 , wherein the at least one layer comprises an inner layer of biodegradable material disposed on the inner surface of the graft material claim 1 , and further comprises at least one outer layer of biodegradable material disposed on the outer surface of the graft material.4. The prosthesis of claim 3 , wherein a segment of the inner layer and an adjacent segment of the ...

FLEXIBLE STENT WITH NON-BONDED STENT COVER MATERIAL REGIONS

A prosthesis is provided for a variety of medical treatments. The prosthesis may include an expandable tubular frame structure and a covering disposed along the frame structure. A proximal liner may be situated along a proximal end of the frame, a distal liner may be situated along a distal end of the frame, and an intermediate liner may be between the proximal liner and the distal liner along the frame. The intermediate liner comprises an extended layer that meets and bonds to the proximal liner and the distal liner at their respective ends. A method of manufacturing the prosthesis is also provided. 1. A prosthesis comprising:an expandable tubular frame structure having a proximal frame end and a distal frame end;a covering disposed along the frame structure, the covering including a first liner, a proximal liner, and a distal liner discrete from the proximal liner, the first liner comprising a plurality of first liner layers, wherein at least one of the first liner layers is an extended layer extending beyond a proximal end of the remaining first liner layers and a distal end of the remaining first liner layers of the first liner,wherein a proximal end of the extended layer is bonded to the proximal liner along the proximal frame end at a first coupling segment, and a distal end of the extended layer is bonded to the distal liner along the distal frame end at a second coupling segment, andwherein one of the first liner layers immediately adjacent to the expandable tubular frame structure remains unbonded to the expandable tubular frame structure along an intermediate region of the frame structure disposed between the proximal and distal frame ends.2. The prosthesis of claim 1 , wherein the first and second coupling segments have a common wall thickness claim 1 , and an intermediate segment of the first liner that remains unbonded to the expandable tubular frame structure comprises a wall thickness sized the same as the common wall thickness.3. The prosthesis of ...

GRAFT MATERIAL WITH INTERNAL FOLDS AND METHOD OF USE THEREOF

The present disclosure relates to a layered graft material and to implantable medical devices including such a graft material. In one embodiment, the device is a stent-graft. In other embodiments, the invention relates to methods of manufacturing and using such devices. In one embodiment the graft is formed of at least three layers, including a folded central layer. 1. A tubular graft material having a radially compressed state and a radially expanded state , the graft material comprising:a first tubular layer extending longitudinally from a first end to a second end;a second tubular layer extending longitudinally from the first end to the second end; anda third tubular layer extending longitudinally from the first end to the second end,wherein the third layer is positioned between the first tubular layer and the second tubular layer, wherein the third layer comprises a radially unfolded region and, in the radially compressed state, a radially folded region, andwherein the third tubular layer is fixed to the first tubular layer and the second tubular layer only in the radially unfolded region.2. The graft material of claim 1 , wherein the first tubular layer and the second tubular layer are formed of a material that is radially stretchable between the compressed state and the expanded state.3. The graft material of claim 2 , wherein the third tubular layer is formed of a material that is less radially stretchable between the compressed state and the expanded state than the material forming the first and second tubular layers.4. The graft material of claim 3 , wherein expansion from the radially compressed state to the radially expanded state causes at least a partial radial unfolding of the third tubular layer.5. The graft material of claim 1 , wherein the first tubular layer and the second tubular layer comprise a material selected from the group consisting of electrospun polytetrafluoroethylene claim 1 , polyurethane and fluorinated ethylene propylene.6. The graft ...

STENT GRAFT TRIGGER WITH INDIRECT FIXATION

Disclosed herein are systems and methods for delivering a medical device to a body vessel of a patient. The medical device may be a stent graft, and the delivery assembly may include at least one loop that connects an end stent of the stent graft to a trigger wire of the delivery assembly, thereby providing indirect connection between the device to be delivered and the trigger wire. 1. A system for deploying at least a portion of a stent , the system comprising:a cannula comprising a lumen;a guide member coupled to the cannula, the guide member comprising an outer surface, the guide member defining at least one curved channel therein, the at least one curved channel defining a trigger wire lumen, the guide member comprising at least one access port through the outer surface to the curved channel; anda trigger wire disposed in the trigger wire lumen.2. The system of claim 1 , wherein the curved channel is a helical channel.3. The system of claim 1 , wherein the guide member defines two curved channels therein.4. The system of claim 3 , wherein the two curved channels do not intersect.5. The system of claim 1 , further comprising a sleeve disposed about at least a portion of the cannula.6. The system of claim 5 , wherein the sleeve is disposed about a portion of the trigger wire.7. The system of claim 1 , wherein the guide member comprises a plurality of access ports through the outer surface and in communication with the curved channel.8. The system of claim 1 , further comprising a tip disposed proximal the guide member claim 1 , the tip defining a cavity in which a portion of the trigger wire is disposed.9. The system of claim 1 , further comprising a loop disposed about the trigger wire and extending at least partially into the access port.10. The system of claim 9 , comprising a first loop and a second loop claim 9 , the first loop having a first length claim 9 , the second loop having a second length greater than the first length.11. The system of claim 1 , ...

Graft prosthesis with pocket for microsystem

A medical device, such as a prosthesis, may include a graft material and a pocket disposed along at least one of luminal and abluminal surfaces of the graft material. The pocket may include a pocket opening leading into an enclosed cavity. The enclosed cavity may be sized to receive at least a portion of a microsystem, and the pocket may be accessible in vivo for removal of the microsystem from the pocket.

CURVED PASSAGEWAY CONFORMING BALLOON CATHETER WITH NESTED BALLOONS

A balloon catheter includes a first balloon positioned inside of a second balloon, both of which are mounted about a catheter and fluidly connected to respective inflation lumens. In a first inflated configuration, the second balloon is inflated and has a shape that includes a plurality of bulb segments, with each two consecutive bulb segments being separated by a waist hoop. In a second inflated configuration both the inner and outer balloons are inflated, and the inner balloon bears radially outwardly against the waist hoop of the outer balloon such that the waist hoop of the outer balloon has a larger diameter in the second inflated configuration than in the first inflated configuration. The bulb segment separated by waist hoops enable the balloon catheter to conform to curved passageways, such as during the implementation of a stent. 1. A balloon catheter comprising:a catheter that defines a first inflation lumen and a second inflation lumen;a first balloon mounted about the catheter and fluidly connected to the first inflation lumen;a second balloon mounted about the catheter and fluidly connected to the second inflation lumen;wherein the first balloon is positioned inside the second balloon;the balloon catheter having a deflated configuration, a first inflated configuration and a second inflated configuration;the first inflated configuration being characterized by the second balloon being inflated and having a shape that includes a plurality of bulb segments, and each two consecutive bulb segments being separated by a waist hoop, and each of the bulb segments having a diameter greater than a diameter of the waist hoop; andthe second inflated configuration being characterized by the second balloon being inflated and the first balloon being inflated, and the first balloon bearing radially outward on the waist hoop such that the waist hoop has a larger diameter in the second inflated configuration than in the first inflated configuration.2. The balloon catheter ...

Bifurcated stent graft with hemodynamic blood flow dividing wall

A bifurcated stent graft includes a stent graft body that defines exactly one main body opening and at least two exit openings. The stent graft body includes at least one stent attached to a graft fabric material, and includes a dividing wall that divides a combined flow path, into a first flow path and a second flow path that each terminate at one of the respective exit openings. The dividing wall includes a thickness profile that terminates at a leading edge radius that extends across a width of the combined flow path.

Flexible stent with non-bonded stent cover material regions

A prosthesis is provided for a variety of medical treatments. The prosthesis may include an expandable tubular frame structure and a covering disposed along the frame structure. A proximal liner may be situated along a proximal end of the frame, a distal liner may be situated along a distal end of the frame, and an intermediate liner may be between the proximal liner and the distal liner along the frame. The intermediate liner comprises an extended layer that meets and bonds to the proximal liner and the distal liner at their respective ends. A method of manufacturing the prosthesis is also provided.

STENT DEPLOYMENT SYSTEM WITH UNWRAPPING DEPLOYMENT CONSTRAINT

A stent delivery system includes a self expanding stent positioned about a distal support segment of a catheter, which includes a proximal segment. A constraint has a wrapped configuration, which has a hollow elongated shape, and an unwrapped configuration, which is a continuous length of a strip. The stent is in contact with, and held in a compressed state by, the constraint in the wrapped configuration, and the stent is in an expanded state out of contact with the constraint in the unwrapped configuration. The constraint may move from the wrapped configuration toward the unwrapped configuration responsive to tension in a control line connected to one end of the strip. 1. A stent delivery system comprising:a catheter having a distal support segment and a proximal segment;a self-expanding stent positioned about the distal support segment;a constraint having a wrapped configuration, which has a hollow elongated shape, and an unwrapped configuration, which is continuous length of a strip;wherein the stent is in contact with, and held in a compressed state by, the constraint in the wrapped configuration, and the stent is in an expanded state out of contact with the constraint in the unwrapped configuration; andwherein the constraint includes the strip wrapped onto itself in a plurality of layers in the wrapped configuration.2. The stent delivery system of wherein the constraint includes a plurality of coils arranged in a series along the axis; andeach of the coils includes the strip wrapped onto itself in the plurality of layers in the wrapped configuration.3. The stent delivery system of wherein the coils unwrap sequentially responsive to the constraint changing from the wrapped configuration toward the unwrapped configuration.4. The stent delivery system of wherein the constraint unwraps from a proximal end toward a distal end of the distal support segment when changing from the wrapped configuration to the unwrapped configuration.5. The stent delivery system of ...

ACTIVE IMPLANTABLE MEDICAL DEVICE AND METHOD OF USING AN ACTIVE IMPLANTABLE MEDICAL DEVICE

An active implantable medical device comprises an expandable stent, a flexible cover material positioned on at least an outer surface of the expandable stent, a nanoscale source of electrical energy embedded within the cover material, where the nanoscale source of electrical energy is mechanically activatable to produce the electrical energy, and antimicrobial particles distributed on or within a surface region of the cover material. The antimicrobial particles are electrically connected to the nanoscale source of electrical energy. When the active implantable medical device is placed in a body vessel and exposed to pressure changes and/or mechanical stresses, mechanical activation of the nanoscale source occurs, thereby enabling production of the electrical energy and powering of the antimicrobial particles. 1. An active implantable medical device comprising:an expandable stent;a flexible cover material positioned on at least an outer surface of the expandable stent;a nanoscale source of electrical energy embedded within the cover material, the nanoscale source of electrical energy being mechanically activatable to produce the electrical energy; andantimicrobial particles distributed on or within a surface region of the cover material, the antimicrobial particles being electrically connected to the nanoscale source of electrical energy,wherein, when the active implantable medical device is placed in a body vessel and exposed to pressure changes and/or mechanical stresses, mechanical activation of the nanoscale source occurs, thereby enabling production of the electrical energy and powering of the antimicrobial particles.2. The active implantable medical device of claim 1 , wherein the nanoscale source of electrical energy comprises a piezoelectric material and/or a triboelectric material.3. The active implantable medical device of claim 2 , wherein the piezoelectric material is selected from the group consisting of: graphene claim 2 , graphite claim 2 , carbon ...

AORTIC STENT GRAFT WITH DURABLE SUTURE ATTACHMENT SITES

An aortic stent graft includes a stent with a framework attached to a fabric tube by a plurality of suture ties. The fabric tube includes a plurality of discrete attachment areas that are at least partially surrounded by at least one permeable graft area. The fabric tube is one of a weave and a knit of thermoplastic yarn. Each of the suture ties associated with the discrete attachment areas at least one of penetrates through and encircles a respective one of the discrete attachment areas. The weave or knit of the discrete attachment areas is identical to that of the permeable graft area with an exception that a wall thickness of each of the discrete attachment areas is flattened relative to, and thinner than, a wall thickness of the permeable graft area. 1. An aortic stent graft comprising:a stent that includes a framework;a fabric tube that includes a plurality of discrete attachment areas that are each at least partially surrounded by at least one permeable graft area, and the fabric tube is one of a weave or a knit of thermoplastic yarn;a plurality of suture ties that attach the framework to the fabric tube, and each of the suture ties at least one of penetrates through and encircles a respective one of the discrete attachment areas; andwherein the weave or the knit of the discrete attachment areas is identical to that of the permeable graft area with an exception that a wall thickness of each of the discrete attachment areas is flattened relative to, and thinner than, a wall thickness of the permeable graft area.2. The aortic stent graft of wherein the weave or the knit at the discrete attachment areas are plastically deformed relative to the weave or the knit of the permeable graft area.3. The aortic stent graft of wherein the discrete attachment areas are less permeable than the permeable graft area.4. The aortic stent graft of wherein the framework includes an anchoring portion; andthe anchoring portion is attached to the discrete attachment areas with a ...

REINFORCED GRAFT PROSTHESIS

A medical device, such as a prosthesis, and method of forming the same are disclosed. The medical device includes a cover material and a reinforcement element, and may include a stent frame structure. The reinforcement element includes a plurality of bends disposed about a pattern axis. The pattern axis is arranged helically along the cover material. 1. A prosthesis comprising:a radially expandable stent frame structure;a cover material disposed along the stent frame structure; anda reinforcement element coupled to the cover material, the reinforcement element having a plurality of bends disposed about a pattern axis, the pattern axis arranged helically along the cover material.2. The prosthesis of claim 1 , wherein the reinforcement element is embedded to within the cover material.3. The prosthesis of claim 2 , wherein the stent frame structure is embedded within the cover material.4. The prosthesis of claim 1 , wherein the cover material includes an outer layer disposed along an outer surface of the frame structure claim 1 , and an inner layer is disposed along an inner surface of the frame structure.5. The prosthesis of claim 1 , wherein at least one of the outer layer and the inner layer comprises a plurality of microlayers claim 1 , and the reinforcement element is disposed between the microlayers.6. The prosthesis of claim 1 , wherein the reinforcement element is a single yarn.7. The prosthesis of claim 1 , wherein the prosthesis includes a proximal end and a distal end claim 1 , wherein the reinforcement element in a stretched configuration without the plurality of bends has a longitudinal length at least twice a longitudinal length measured between the proximal and distal ends of the prosthesis.8. The prosthesis of claim 1 , wherein the plurality of bends of the reinforcement element is disposed generally in an undulating pattern about the pattern axis claim 1 , wherein one of the plurality of bends forms each undulation of the undulating pattern.9. The ...

GUIDEWIRE WITH CONTROLLABLE STIFFNESS

The disclosure generally relates to a guidewire with controllable stiffness and to a method of use thereof. A distal section of the guidewire includes a core wire, a shape memory coil, and a distal element electrically connecting the core wire to the shape memory coil. The shape memory coil has an expanded configuration with smaller stiffness and a compressed configuration having larger stiffness. Upon passage of an electric current through the shape memory coil, the shape memory coil may switch between the expanded and compressed configurations, thus changing the stiffness of the distal section of the guidewire.

VASCULAR FORCE REDUCTION SYSTEM

A system includes a medical device having a proximal end, a distal end, and a section of material between the proximal and distal ends. The system also includes a vascular force reduction system positioned along the section, including at least one support structure supporting at least one rotating assembly, the at least one rotating assembly having a vessel contact surface, wherein the at least one rotating assembly is configured to rotate substantially toward the proximal and the distal ends of the medical device. 1. A system , comprising:a medical device comprising a proximal end, a distal end, and a section of material between the proximal and distal ends; anda vascular force reduction system positioned along the section, comprising at least one support structure supporting at least one rotating assembly, the at least one rotating assembly having a vessel contact surface,wherein the at least one rotating assembly is configured to rotate substantially toward the proximal and the distal ends of the medical device.2. The system of claim 1 , wherein the at least one rotating assembly comprises a bearing.3. The system of claim 1 , wherein the at least one rotating assembly comprises a band.4. The system of claim 2 , wherein the band comprises a traction element.5. The system of claim 2 , wherein the at least one rotating assembly comprises a plurality of rotating elements connected by the band.6. The system of claim 1 , wherein the section of material comprises an endovascular device.7. The system of claim 1 , wherein the section of material comprises a guidewire.8. The system of claim 1 , wherein the section of material comprises a catheter.9. The system of claim 1 , wherein the at least one support structure is formed integrally to the section of material.10. The system of claim 1 , wherein the at least one support structure comprises a guard.11. The system of claim 1 , wherein the at least one support structure comprises an aperture.12. The system of claim 1 , ...

Graft material and method of use thereof

The present disclosure relates to a graft material including a reinforced layer and to implantable medical devices including such a graft material. The invention also relates to methods of using and manufacturing such graft materials and devices. In one embodiment the implantable medical device is a stent graft.

Low profile stent delivery system and method

A low profiled stent delivery system includes a balloon catheter with a balloon mounted at a first location, and a balloon expandable stent crimped about the balloon catheter at a second location. The stent expands from a crimped state to a less than fully expanded state responsive to movement of an auxiliary expander from a first configuration to a second configuration. An inner diameter of the stent in the less than fully expanded state is greater than an outer diameter of the balloon in a deflated state. After repositioning the balloon within the less than fully expanded state, the balloon is inflated to fully expand the stent.

LOW PROFILE STENT DELIVERY SYSTEM AND METHOD

A low profiled stent delivery system includes a balloon catheter with a balloon mounted at a first location, and a balloon expandable stent crimped about the balloon catheter at a second location. The stent expands from a crimped state to a less than fully expanded state responsive to movement of an auxiliary expander from a first configuration to a second configuration. An inner diameter of the stent in the less than fully expanded state is greater than an outer diameter of the balloon in a deflated state. After repositioning the balloon within the less than fully expanded state, the balloon is inflated to fully expand the stent. 1. A low profile stent delivery system comprising:a balloon catheter that includes a catheter and a balloon mounted about the catheter at a first location along a length of the catheter;a balloon expandable stent crimped about the catheter at a second location that is separated from the first location;an auxiliary expander that is movable with respect to the stent between a first configuration and a second configuration;wherein stent expands from a crimped state to a less than fully expanded state responsive to movement of the auxiliary expander from the first configuration to the second configuration; andwherein an inner diameter of the stent in the less than fully expanded state is greater than an outer diameter of the balloon in a deflated state.2. The low profile stent delivery system of including a sheath that is seven French or less; andwherein the balloon catheter and the auxiliary expander are sized to be slidably received through the sheath.3. The low profile stent delivery system of wherein the balloon is a main balloon;the auxiliary expander includes an auxiliary balloon mounted about the catheter at the second location, and being deflated in the first configuration and inflated in the second configuration;an outer diameter of the main balloon in an inflated state is greater than an outer diameter of the auxiliary balloon in an ...

Graft material and method of use thereof

The present disclosure relates to woven and knitted fabrics including boron nitride nanotubes and to methods of manufacturing and using such materials. In one embodiment, these materials are incorporated into implantable medical devices such as stent graft devices and the like.

ARTICULAR VASCULAR IMPLANTS USING POLYMAGNETS

An implantable medical device includes a first section and a second section, and an interface region between the first and second sections. A magnet array overlies each of opposing surfaces of each of the first and second sections at least at the interface region. The magnet arrays include a plurality of magnetic elements arranged in a predetermined pattern, each of the plurality of magnetic elements having a north and a south pole. The predetermined pattern is such that the north and south poles of the magnetic elements in each magnetic arrays are conjugated with one another so as to define a variable magnetic field between the first and second sections. 1. An implantable medical device comprising:a first section and a second section;an interface region between the first and second sections;a magnet array overlying each of opposing surfaces of each of the first and second sections at least at the interface region, the magnet arrays including a plurality of magnetic elements arranged in a predetermined pattern, each of the plurality of magnetic elements having a north and a south pole,wherein the predetermined pattern is such that the north and south poles of the magnetic elements in each magnetic arrays are conjugated with one another so as to define a variable magnetic field between the first and second sections.2. The implantable medical device of claim 1 , wherein the first and second sections each comprise a tubular structure having different diameters claim 1 , such that the first section has a smaller diameter than the second section and the interface region comprises an annulus between end regions of the first and second sections.3. The implantable medical device of claim 2 , wherein the magnet arrays at the interface region each comprise a regular array of magnetic elements.4. The implantable medical device of claim 2 , wherein the magnet arrays at the interface region each comprise an irregular array of magnetic elements.5. The implantable medical device ...

Aortic stent graft with durable suture attachment sites

An aortic stent graft includes a stent with a framework attached to a fabric tube by a plurality of suture ties. The fabric tube includes a plurality of discrete attachment areas that are at least partially surrounded by at least one permeable graft area. The fabric tube is one of a weave and a knit of thermoplastic yarn. Each of the suture ties associated with the discrete attachment areas at least one of penetrates through and encircles a respective one of the discrete attachment areas. The weave or knit of the discrete attachment areas is identical to that of the permeable graft area with an exception that a wall thickness of each of the discrete attachment areas is flattened relative to, and thinner than, a wall thickness of the permeable graft area.

Curved passageway conforming balloon catheter with nested balloons

A balloon catheter includes a first balloon positioned inside of a second balloon, both of which are mounted about a catheter and fluidly connected to respective inflation lumens. In a first inflated configuration, the second balloon is inflated and has a shape that includes a plurality of bulb segments, with each two consecutive bulb segments being separated by a waist hoop. In a second inflated configuration both the inner and outer balloons are inflated, and the inner balloon bears radially outwardly against the waist hoop of the outer balloon such that the waist hoop of the outer balloon has a larger diameter in the second inflated configuration than in the first inflated configuration. The bulb segment separated by waist hoops enable the balloon catheter to conform to curved passageways, such as during the implementation of a stent.

LAYERED COVER MATERIAL AND METHOD OF USE THEREOF

The present disclosure relates to a multi-layered cover including a reinforcement layer including polytetrafluoroethylene and an attached bonding layer, and to implantable medical devices including such a cover. In one embodiment, the bonding layer includes at least one of polyurethane, silicone and fluorinated ethylene propylene. Other aspects of the invention relate to methods of manufacturing and using such implantable devices.

Active implantable medical device and method of using an active implantable medical device

An active implantable medical device comprises an expandable stent, a flexible cover material positioned on at least an outer surface of the expandable stent, a nanoscale source of electrical energy embedded within the cover material, where the nanoscale source of electrical energy is mechanically activatable to produce the electrical energy, and antimicrobial particles distributed on or within a surface region of the cover material. The antimicrobial particles are electrically connected to the nanoscale source of electrical energy. When the active implantable medical device is placed in a body vessel and exposed to pressure changes and/or mechanical stresses, mechanical activation of the nanoscale source occurs, thereby enabling production of the electrical energy and powering of the antimicrobial particles.

SELF-HEALING GRAFT MATERIAL AND METHOD OF USE THEREOF

The present disclosure relates to a graft material including a self-healing polymer layer and to implantable medical devices including such a graft material. The invention also relates to methods of using and manufacturing such graft materials and devices. In one embodiment, the implantable medical device is a stent graft.

Deploying a balloon expandable stent to induce spiral flow

A balloon expanded stent delivery system includes an inflation constraint, such as a wire, spirally wound about the longitudinal axis in contact with a balloon and attached to an underlying catheter. A balloon expanded stent is mounted about the balloon and the inflation constraint. The delivery system has a predeployment configuration with the balloon deflated and the stent unexpanded. The system has a deployment configuration in which the inflation constraint constrains the inflated balloon to a spiral shape, the stent is expanded and in contact with the balloon, and the stent has a flow directing surface with a spiral contour that matches the spiral shape of the balloon. In a postdeployment configuration, the stent retains the flow directing surface with the spiral contour.

Data storage on implantable magnetizable fabric

The disclosure is directed to a system, device and method for data storage on implantable magnetizable fabric. The system includes implantable magnetizable fabric coupled to a graft segment of a prosthesis for being delivered into a body of a subject. The system includes information written on the implantable magnetizable fabric. The system further includes a magnetic detection device capable of, after the prosthesis is delivered into the body of the subject, detecting the implantable magnetizable fabric and accessing at least a portion of the information.

Funnel-shaped pressurization valve

The disclosure is directed to a system for maintaining hemostasis during introducing or withdrawing an interventional device. The system includes a housing. The housing includes a first end, a second end and a side wall defining a housing chamber. The system also includes a first funnel-shaped member disposed at least partially within the housing chamber. The first funnel-shaped member includes an inner portion, a middle portion and an outer portion. The inner portion of the first funnel-shaped member includes an elastic orifice, which is aligned with the through channel of the housing. The first funnel-shaped member includes an open configuration and a closed configuration. When the first funnel-shaped member is in the closed configuration, the elastic orifice is substantially closed, and when the first funnel-shaped member is in the open configuration, an interventional device is introduced through the system and the elastic orifice is open.

Low profile stent delivery system and method

Reinforced graft prosthesis

A medical device, such as a prosthesis, and method of forming the same are disclosed. The medical device includes a cover material (12) and a reinforcement element (14), and may include a stent frame structure (35). The reinforcement element (14) includes a plurality of bends disposed about a pattern axis. The pattern axis is arranged helically along the cover material.

Flexible stent with non-bonded stent cover material regions

A prosthesis (100) is provided for a variety of medical treatments. The prosthesis (100) may include an expandable tubular frame structure (110) and a covering (120) disposed along the frame structure (110). A proximal liner (210) may be situated along a proximal end of the frame, a distal liner (220) may be situated along a distal end of the frame, and an intermediate liner may be between the proximal liner and the distal liner along the frame. The intermediate liner comprises an extended layer that meets and bonds to the proximal liner and the distal liner at their respective ends. A method of manufacturing the prosthesis is also disclosed.

Graft prosthesis with pocket for microsystem

A medical device, such as a prosthesis, may include a graft material and a pocket (30) disposed along at least one of luminal and abluminal surfaces of the graft material. The pocket may include a pocket opening leading into an enclosed cavity. The enclosed cavity may be sized to receive at least a portion of a microsystem (M), and the pocket may be accessible in vivo for removal of the microsystem from the pocket (30).

Low profile stent delivery system and method

A low profiled stent delivery system includes a balloon catheter with a balloon mounted at a first location, and a balloon expandable stent crimped about the balloon catheter at a second location. The stent expands from a crimped state to a less than fully expanded state responsive to movement of an auxiliary expander from a first configuration to a second configuration. An inner diameter of the stent in the less than fully expanded state is greater than an outer diameter of the balloon in a deflated state. After repositioning the balloon within the less than fully expanded state, the balloon is inflated to fully expand the stent.

A balloon expandable stent for inducing spiral flow

Active implantable medical device and method of its use