12-07-2018 дата публикации
Номер: US20180195128A1
Принадлежит:
The invention relates to improved methods, devices, and kits for identifying and implementing an appropriate treatment regimen for subjects suffering from hypertension. 165-. (canceled)68. A method according to wherein the DNA analyses are conducted sequentially or simultaneously.69. A method according to wherein the DNA analyses are conducted simultaneously.70. A method according to wherein the DNA and/or polypeptide analyses are conducted sequentially or simultaneously.71. A method according to wherein the DNA and/or polypeptide analyses are conducted simultaneously.72. A method according to comprising administering to the patient a second line antihypertensive drug after administration of the first line drug administration for at least one month wherein the second line drug is selected from the group consisting of diuretic claim 66 , a beta-blocker claim 66 , an ACE inhibitor claim 66 , a vasodilator and a combination thereof claim 66 , and the second line drug is not the same as the first line drug.73. A method according to wherein at least one additional polymorphism is present in the patient's one or more DNA sequences corresponding to DNA sequences 1-14 and the administration procedures are the same as those of procedures a-f.74. A method according to wherein a diuretic is furosemide claim 66 , a thiazide claim 66 , a carbonic anhydrase inhibitor claim 66 , an aldosterone antagonist claim 66 , spironolactone claim 66 , eplerenone claim 66 , potassium canreonate claim 66 , amiloride claim 66 , triamterene claim 66 , aldactone claim 66 , acetazolamide claim 66 , amiloride claim 66 , bumetanide claim 66 , chlorothalidone claim 66 , chlorothiazide claim 66 , ethacrynic acid claim 66 , furosemide claim 66 , glycerin claim 66 , hydrochlorothiazide claim 66 , hydroflumthiazide claim 66 , indapamide claim 66 , isosorbide claim 66 , mannitol claim 66 , methazolamide claim 66 , methylchlothiazide claim 66 , metolazone claim 66 , dichlorphenamide claim 66 , ...
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