SYSTEMS FOR DETECTING CARDIAC ARRHYTHMIAS

A system for calculating a variability value that is indicative of AF by obtaining a signal sequence of a plurality of RR intervals by monitoring electrical activity of a patient's heart. Each RR interval is converted into an instantaneous heart rate value and sorted into ascending order. The difference between each successive heart rate is calculated, discarding the two largest differences. The variability value is calculated by adding the retained differences. 1. A system for calculating a variability value that is indicative of AF using a sequence of RR intervals , wherein said system comprises a non-volatile computer readable medium storing a plurality of programmatic instructions and wherein said programmatic instructions , when executed:obtain a signal sequence comprising a plurality of RR intervals wherein said signal sequence is obtained by monitoring the time intervals between successive heart beats of a patient's heart by measuring at least one of electrical activity; acoustic activity; trans-thoracic impedance; blood pressure; blood velocity; blood oxygenation; heart movement and/or deformation;convert each RR interval in said sequence into an instantaneous heart rate value;sort said instantaneous heart rate values into ascending order;calculate the difference between each successive heart rate;discard the two largest differences generated in the previous step; andcalculate a variability value by adding the retained differences.2. The system of claim 1 , wherein said programmatic instructions claim 1 , when executed claim 1 , also segment said RR interval sequence into a plurality of segments and generate a variability value for each said segment.3. The system of claim 2 , wherein said programmatic instructions claim 2 , when executed claim 2 , also filter said generated variability value for at least one segment using previous or successive segment variability values.4. The system of wherein said filtering is implemented by a 7-sample median filter.5. ...

Method and Apparatus for Composite User Interface Generation

A method for directing messages between a composite user interface and at least one source application. A message is to be directed to a predetermined set of services, each service executes a command specified by the message and the message comprises details of the predetermined set of services. Each service in the predetermined set of services uses said details to determine whether the message should be sent to another service, and if it is determined that the message should be sent to another service transmits the message to an appropriate service. 1. A method of directing messages within a computer system , wherein:a message is to be directed to a predetermined set of services;each service executes a command specified by the message;the message comprises details of the predetermined set of services; andeach service in the predetermined set of services uses said details to determine whether the message should be sent to another service, and if it is determined that the message should be sent to another service transmits the message to an appropriate service.2146-. (canceled) The present invention relates to methods and systems for generating composite user interfaces, and to methods and systems for directing messages between a composite user interface and a plurality of source applications.Computer users routinely need to use a plurality of different applications in order to complete tasks allocated to them, and each application typically has a separate user interface. Switching between the different user interfaces of the different applications in order to complete a given task considerably degrades user efficiency. It will often be the case that different applications are supplied by different vendors and accordingly their user interfaces have a different “look and feel”, further degrading operator efficiency.For example, in order to process customer enquiries, operators in a call centre may need to access a customer management application to access customer ...

U-Bend Tube Compression/Distortion Stabilization System (CDSS)

This patent discloses and claims a system for providing in-plane stabilization to the tubes of a heat exchanger. The system increases the friction between the tubes and the existing anti-vibration bars by pressing the tube bundle together in the out-of-plane direction. The invention involves a structure that develops forces by reacting either off the inner diameter of the tube bundle wrapper, or off an assembled stressor hoop, which is self-supporting on top of the tube bundle, or involves purposely deforming connecting hoops to bias the anti-vibration bars in a way that the tube U-bend is no longer planar. It imposes a controlled clamping and/or deforming force on the tube bundle, either by direct contact with the outer tubes or indirectly via the existing anti-vibration bar structure. 1. A system imparting in-plane stability to a heat exchanger having U-bend tubes with anti-vibration bars running therebetween , comprising:a plurality of load blocks positioned so as to be in contact with at least some of the anti-vibration bars;a hoop coupled to each of said load blocks;wherein said hoop is tensioned to provide an inwardly directed force to the U-bend tubes through the load blocks and anti-vibration bars.2. The system of wherein said hoop is tensioned so as to apply forces to said load blocks claim 1 , said forces being balanced across opposite sides of the U-tubes and located to both compress and controllably deform the U-bend region such that controlled contact forces are generated between the anti-vibration bars and the U-bend tubes.3. The system of claim 1 , wherein said hoop is tensioned so as to induce contact bets teen at least one of the U-bend tubes and an adjacent one of the anti-vibration bars.4. The system of claim 3 , wherein said hoop is adjustably tensioned.5. The system of claim 4 , wherein said hoop is designed to support a load of approximately 1000 to 9000 lbs.6. The system of claim 1 , wherein at least one of said load blocks includes a body ...

Viscous Damping Stabilizer

The inventive viscous damping tube stabilizer includes modules or capsules containing a viscous material. Adjacent capsules are linked end to end by a flexible cable, allowing the device o pass through curves such as the U-bend regions of steam generator tubes. The weight of the entire assembly will keep it essentially connected to the tube inner diameter such that any tube vibration is transmitted to the stabilizer. The viscous material may only partially fill the capsules such that even under small motion the material can slip and slide past each other, and/or bump into walls, each microscopically absorbing some of the tube energy. By creating multiple cells inside the capsule, the capsule then have good operating characteristics no matter to what angle the individual capsule is oriented as it rests on the full U-bend. The viscous material may completely fill the capsules, which also have a perforated member positioned therein. Relative movement of the capsule and disc causes the viscous material to pass through the perforations, providing damping resistance to the movement. 1. A stabilizer for use with a hollow tube , comprising a plurality of capsules , adjacent ones of said capsules being interconnected by a flexible linking member , said capsules containing damping material that is free to move about an interior volume of said capsules.2. The stabilizer of claim 1 , wherein at least one of said capsules defines a plurality of subcompartment therein claim 1 , each of said subcompartments containing damping material.3. The stabilizer of claim 2 , wherein each of said subcompartment defines a volume that is partially filled with damping material.4. The stabilizer of claim 3 , wherein each of said subcompartment volumes is 40%-60% filled with damping material.5. The stabilizer of claim 1 , wherein at least one of said capsules further includes a perforated member therein claim 1 , said capsule being substantially filled with damping material.6. The stabilizer of ...

METHODS AND SYSTEMS FOR SYNTHESIZING ELECTROCARDIOGRAPHIC SIGNALS USING POSTURE DATA

The present specification discloses methods and systems for synthesizing electrocardiographic (ECG) signals. In one method, a first group of electrodes are attached to predetermined locations on the human body. A posture sensor is attached to the human body and generates data indicative of the human body's posture. The system receives signals from the first group of electrodes connected to the predetermined locations on a human body and acquires a first set of ECG signals. The system then derives at least one further ECG signal by applying transformation(s) on the first set of ECG signals, or a subset thereof, to form a desired set of signals, where the applied transformations are selected based on the human body's posture. 1. A method of synthesizing electrocardiographic (ECG) signals comprising:attaching a first group of electrodes to predetermined locations on the human body;attaching a posture sensor on said human body, wherein the posture sensor generates data indicative of the human body's posture;receiving signals from the first group of electrodes connected to the predetermined locations on a human body to acquire a first set of ECG signals; andderiving at least one further ECG signal by applying transformation(s) on said first set of ECG signals, or a subset thereof, to form a desired set of signals, wherein the applied transformations are selected based on the human body's posture.2. The method of synthesizing electrocardiographic (ECG) signals of wherein the posture sensor is located on an electrocardiograph lead device.3. The method of synthesizing electrocardiographic (ECG) signals of wherein the human body's posture is at least one of a predefined set of postures.4. The method of synthesizing electrocardiographic (ECG) signals of wherein each of said predefined set of postures is associated with its own fixed set of transformations.5. The method of synthesizing electrocardiographic (ECG) signals of wherein the human body's posture is one of torso ...

ALUMINUM MELTING APPARATUS

A method and apparatus for melting aluminum uses a dense metal salt of Rubidium, Cesium, or Strontium. The salt is melted by a stinger and then superheated by AC applied to electrodes immersed in the salt. Aluminum in contact with the salt melts and floats on the salt. In continuous scrap melting, inflows and outflows of aluminum are comparable and may be shielded by inert gas. The superheated salt may be purified and may be heated in a separate reservoir and pumped to and from another reservoir containing salt and/or metal. The salt may be used to supplement the heating of an existing furnace. 1. An apparatus for melting aluminum , comprising:a receptacle having a first portion capable of containing a salt, and a second portion capable of containing aluminum, the first portion being disposed below and in fluid communication with the second portion;a salt of at least one of the metals selected from the group Rubidium, Cesium, and Strontium disposed in the first portion, the salt having a density greater than molten aluminum;a pair of spaced electrodes disposed in the first portion;a source of electrical power capable of establishing an electrical potential between the spaced electrodes, the salt supporting an electric current between the electrodes that heats the salt through Joule heating to a temperature above the melting point of aluminum.2. The apparatus of claim 1 , further comprising a cover disposed over the second portion.3. The apparatus of claim 2 , further comprising a non-reactive gas present in the receptacle between the aluminum in the second receptacle and the cover.4. The apparatus of claim 3 , wherein the gas is Argon.5. The apparatus of claim 1 , wherein the receptacle is divided into a first receptacle for the first portion and a second receptacle for the second portion claim 1 , the first and second receptacles in fluid communication.6. The apparatus of claim 5 , further comprising a pump to move the salt between the first receptacle and the ...

IMPROVEMENTS IN AND RELATING TO UNDERWATER EXCAVATION APPARATUS

An excavation apparatus comprises a controlled flow underwater excavation apparatus. A housing thereof comprises at least one inlet and at least one outlet. The at least one inlet is provided on or at a side of the housing. A fluid flow path extends from the/each at least one inlet to the outlet. The fluid flow path comprises a first portion provided at or adjacent the/each at least one inlet. The first portion is included at a non-300 angle, e.g. is substantially perpendicular, to or converges towards a longitudinal axis of the housing and substantially straight. A second portion extends or continues from the first portion. A third portion extends or continues from the second portion. The third portion is substantially straight, contains at least part of a rotor, and is divergent away from the longitudinal axis of the housing in a flow direction from the inlet to the outlet. 1. An excavation apparatus , such as an underwater excavation apparatus , comprising:a housing having at least one inlet and at least one outlet, wherein the at least one inlet is provided on or at a side or sides of the housing;at least one rotor within the housing; andat least one stator within the housing; and whereinan inside of the housing converges from the at least one inlet towards the rotor,the inside of the housing diverges from an inlet end of the rotor towards an outlet end of the rotor, andthe inside of the housing converges from the stator towards the outlet.2. An excavation apparatus as claimed in claim 1 , wherein the at least one inlet is provided around claim 1 , such as circumferentially or peripherally around claim 1 , a side of the housing.3. An excavation apparatus as claimed claim 1 , wherein the housing comprises a longitudinal axis claim 1 , the housing being symmetrical with respect to the longitudinal axis.4. An excavation apparatus as claimed in claim 3 , wherein:the at least one inlet is provided inclined and/or offset from or transversely or substantially ...

Method and Apparatus for Composite User Interface Generation

A method for directing messages between a composite user interface and at least one source application. A message is to be directed to a predetermined set of services, each service executes a command specified by the message and the message comprises details of the predetermined set of services. Each service in the predetermined set of services uses said details to determine whether the message should be sent to another service, and if it is determined that the message should be sent to another service transmits the message to an appropriate service.

Method and Apparatus for Composite User Interface Generation

A method for directing messages between a composite user interface and at least one source application. A message is to be directed to a predetermined set of services, each service executes a command specified by the message and the message comprises details of the predetermined set of services. Each service in the predetermined set of services uses said details to determine whether the message should be sent to another service, and if it is determined that the message should be sent to another service transmits the message to an appropriate service.

Improved Turbine

An improved turbine or motor, such as a fluid or liquid driven turbine or motor or hydraulic turbine or motor including a downhole turbine for the oil/gas and geothermal industries, such as a drilling turbine or downhole drilling turbine. The turbine or motor provides a fluid passage comprising at least one portion or zone arranged to cause a drive fluid to be moved or diverted, such as at least partly radially. The turbine or motor may comprise a rotor having a rotor blade extending within the fluid passage. The turbine or motor may comprise a stator having a stator blade extending within the fluid passage. The stator () may comprise or define at least part of the at least one portion or zone configured or arranged to cause the fluid to be moved in or diverted from an at least part axial path to an at least part radial path or radially inward path. 1105.-. (canceled)106. A turbine or motor , such as a downhole turbine or motor , wherein there is provided a fluid passage comprising at least one portion or zone arranged to cause a drive fluid to be moved or diverted , such as at least partly radially.107. A turbine or motor claim 106 , such as a downhole turbine or motor claim 106 , as claimed in claim 106 , wherein the turbine comprises at least one of:a rotor comprising at least one of:at least one rotor blade extending within the fluid passage;a plurality of circumferentially disposed rotor blades; anda hub which carries the at least one rotor blade;peripherally/circumferentially thereupon;a stator comprising at least one of:at least one stator blade extending within the fluid passage;a plurality of circumferentially disposed stator blades;a stator hub which carries the at least one stator blade;peripherally/circumferentially thereupon; anda tubular housing, the stator being mounted in fixed relation to the tubular housing; anda rotatable shaft, the rotor being mounted in fixed relation to the shaft.108. A turbine or motor claim 107 , such as a downhole turbine or ...

MOBILE MEASUREMENT DEVICES, INSTRUMENTS AND METHODS

A portable instrument or apparatus includes a portable device and a rangefinder module. The rangefinder module can be attached to the portable device, which may be any suitable smartphone, tablet or other consumer electronics device having a camera. By suitable alignment of the rangefinder and camera, the device is capable of capturing accurate data over significant ranges, including for example an image of a target together with position information concerning the target. A folded optical arrangement reduces the volume and thickness of the rangefinder module. 1. A laser rangefinder module configured for attachment to a portable device including a camera having an optical axis , the module including:a laser rangefinder substantially aligned on a rangefinder axis; andone or more optical elements positioned to redirect light so as to substantially align the rangefinder axis and a camera optical axis when the laser range finder module is mounted on a portable device.2. A laser rangefinder module as claimed in including a laser emitter and a laser receiver.3. A laser rangefinder as claimed in wherein the one or more optical elements form a first folded optical path from the range finder axis to the laser receiver.4. A laser rangefinder as claimed in wherein the first folded optical path is formed by two or more mirrors.5. A laser rangefinder as claimed in wherein a first mirror is inclined at an angle of between 50 to 60 degrees to the rangefinder axis.6. A laser rangefinder as claimed in wherein the orientation of the first mirror is adjustable with respect to the rangefinder module.7. A laser rangefinder as claimed in wherein a second mirror is provided substantially parallel to the first mirror.8. A laser rangefinder as claimed in wherein the second mirror is adjustable with respect to the rangefinder module.9. A laser rangefinder as claimed in wherein a Fresnel lens is provided in the optical path prior to the first mirror.10. A laser rangefinder as claimed in ...

CUTTING TOOL

An underwater tool () including a grabber arrangement () and a cutter arrangement () connected together. The grabber arrangement comprises a plurality of grabber elements () disposed on first and second sides () of the tool. The cutter arrangement includes a cutter slot (), an anvil () movable to close the slot comprises an anvil and a cutter blade (). In use, a cable () is held by the grabber arrangement, and thereby moved into the slot which is then closed by the anvil so as to entrap the cable within the slot. The cutter blade is then driven against the anvil so as to cut the cable. 1. An underwater tool comprising a grabber arrangement or means and/or a cutter arrangement or means.2. A tool according to claim 1 , wherein the grabber arrangement and the cutter arrangement are connected together or arranged in a set/preset disposition relative to one another claim 1 , such as a longitudinally set and transversely movable disposition relative to one another.3. A tool according to claim 1 , wherein the grabber arrangement and the cutter arrangement are directly or indirectly connected together claim 1 , such as rigidly connected together claim 1 , such as by one or more rigid members and/or a frame.4. A tool according to claim 1 , wherein the grabber arrangement comprises:a plurality of grabber elements; and/orthe grabber arrangement or grabber elements comprise one or more first grabber elements and one or more second grabber elements.5. A tool according to claim 4 , wherein:the first grabber element(s) is/are disposed on a first side of the tool, and/orthe second grabber element(s) is/are disposed on a second side of the tool, and/orthe first/second grabber elements are pivotably attached to a (main) body of the tool, and/orthe first/second grabber elements comprise arms or fingers, and/orthe/each grabber element is claw, talon or tine shaped; and/orthe first/second grabber elements are curved or arcuate in shape, and optionally in such casea concave surface of ...

Systems for Detecting Cardiac Arrhythmias

A system for calculating a variability value that is indicative of AF by obtaining a signal sequence of a plurality of RR intervals by monitoring electrical activity of a patient's heart. Each RR interval is converted into an instantaneous heart rate value and sorted into ascending order. The difference between each successive heart rate is calculated, discarding the two largest differences. The variability value is calculated by adding the retained differences.

Method and Apparatus for Composite User Interface Generation

A method for directing messages between a composite user interface and at least one source application. A message is to be directed to a predetermined set of services, each service executes a command specified by the message and the message comprises details of the predetermined set of services. Each service in the predetermined set of services uses said details to determine whether the message should be sent to another service, and if it is determined that the message should be sent to another service transmits the message to an appropriate service.

Method and Apparatus for Composite User Interface Generation

A method for directing messages between a composite user interface and at least one source application. A message is to be directed to a predetermined set of services, each service executes a command specified by the message and the message comprises details of the predetermined set of services. Each service in the predetermined set of services uses said details to determine whether the message should be sent to another service, and if it is determined that the message should be sent to another service transmits the message to an appropriate service. 1. A method of directing messages within a computer system , wherein:a message is to be directed to a predetermined set of services;each service executes a command specified by the message;the message comprises details of the predetermined set of services; andeach service in the predetermined set of services uses said details to determine whether the message should be sent to another service, and if it is determined that the message should be sent to another service transmits the message to an appropriate service.2146-. (canceled) The present invention relates to methods and systems for generating composite user interfaces, and to methods and systems for directing messages between a composite user interface and a plurality of source applications.Computer users routinely need to use a plurality of different applications in order to complete tasks allocated to them, and each application typically has a separate user interface. Switching between the different user interfaces of the different applications in order to complete a given task considerably degrades user efficiency. It will often be the case that different applications are supplied by different vendors and accordingly their user interfaces have a different “look and feel”, further degrading operator efficiency.For example, in order to process customer enquiries, operators in a call centre may need to access a customer management application to access customer ...

IMPROVEMENTS IN AND RELATING TO UNDERWATER EXCAVATION APPARATUS

There is disclosed an excavation apparatus (5), such as an underwater excavation apparatus, having means for producing, in use, at least one vortex, spiral or turbulent flow in a laminar flow of fluid, e.g. water. The excavation apparatus (5) comprises a rotor (10) having a rotor rotation axis (A), wherein, in use, flow of fluid passed or across the rotor (10) is at a first angle (a) from the axis of rotation (A). The excavation apparatus (5) comprises the rotor (10) and means or an arrangement for dampening reactive torque on the apparatus (5) caused by rotation of the rotor (10), in use. The turbulent flow is provided within, such as within a (transverse) cross-section, of the laminar flow. 1. An underwater excavation apparatus comprising:a housing comprising an inlet and an outlet;at least one rotor comprising an impeller provided within the housing;at least one stator provided within the housing; andan arrangement for producing at least one vortex in a flow of fluid, whereinthe or each at least one vortex producing arrangement comprises a planar member provided adjacent the outlet of the housing, an edge of the planar member being attached to the housing or to a body within the housing.2. An underwater excavation apparatus as claimed in claim 1 , wherein the at least one vortex producing arrangement comprises a plurality of vortex producing arrangements which together comprise a closed shape.3. An underwater excavation apparatus as claimed in claim 1 , wherein the vortex producing arrangement causes a spiralling movement of fluid flowing out of the excavation apparatus.4. An underwater excavation apparatus as claimed in claim 1 , wherein the excavation apparatus comprises a single rotor.5. An underwater excavation apparatus as claimed in claim 1 , wherein the excavation apparatus comprises a single stator.6. An underwater excavation apparatus as claimed in claim 1 , whereinin a first mode of operation, comprising an excavation mode, the outlet faces an area to ...

Manufacturing process of artificial filaments and films

Power generator and turbine unit

Microchannel laminated mass exchanger and method of making

The present invention is a microchannel mass exchanger having a first plurality of inner thin sheets and a second plurality of outer thin sheets. The inner thin sheets each have a solid margin around a circumference, the solid margin defining a slot through the inner thin sheet thickness. The outer thin sheets each have at least two header holes on opposite ends and when sandwiching an inner thin sheet. The outer thin sheets further have a mass exchange medium. The assembly forms a closed flow channel assembly wherein fluid enters through one of the header holes into the slot and exits through another of the header holes after contacting the mass exchange medium.

Active microchannel fluid processing unit and method of making

The present invention is an active microchannel fluid processing unit and method of making, both relying on having (a) at least one inner thin sheet; (b) at least one outer thin sheet; (c) defining at least one first sub-assembly for performing at least one first unit operation by stacking a first of the at least one inner thin sheet in alternating contact with a first of the at least one outer thin sheet into a first stack and placing an end block on the at least one inner thin sheet, the at least one first sub-assembly having at least a first inlet and a first outlet; and (d) defining at least one second sub-assembly for performing at least one second unit operation either as a second flow path within the first stack or by stacking a second of the at least one inner thin sheet in alternating contact with second of the at least one outer thin sheet as a second stack, the at least one second sub-assembly having at least a second inlet and a second outlet.

Power generator and turbine unit

A power generator 8 comprises an underwater turbine unit 10 including a turbine mounted in a liquid flow channel (14 in fig. 2). The flow channel 14 comprises a venturi comprising a symmetrical divergent-convergent-divergent venturi. In a further embodiment of the invention the turbine is provided with pumping means (18 in fig. 2) for pumping fluid to a generator 20 located separately from the turbine.

Electrode plate with a metal foam type support for an electrochemical generator and method for manufacturing such an electrode plate.

Electrode plate with a metal foam type support for an electrochemical generator, and method for obtaining such an electrode.

Multiple potted-plant self-watering system

A multiple plant container self-watering system comprises a primary container at a first elevation and a plurality of secondary containers at different elevations, fluidly connected by means of tubing. The primary container comprises a primary outer shell that encloses a primary reservoir pot, having an expanded upper portion and a tubular lower portion, a primary wick and a primary grow pot. Each of the plurality of secondary containers comprises a secondary outer shell that encloses a secondary reservoir pot having an expanded upper portion and a tubular lower portion, a secondary wick, and a secondary grow pot. The diameter of the lower portion of the primary and secondary reservoir pot is greatly reduced in comparison to the diameter of the upper portion thereof, thereby allowing for substantially similar dry-down time for a plurality of fluidly connected plant containers at different elevations.

Electrode plate with a metal foam type support for an electrochemical generator, and method for obtaining such an electrode.

La plaque d'électrode comporte une partie active, empâtée de matière active, et une tête de plaque constituée de trois couches de mousse métallique comprimées: une partie, de hauteur G, non empâtée, du support (1) de la plaque d'électrode et deux bandes de mousse métallique (2, 3) non empâtées, de hauteur R qui encadrent la partie non empâtée de hauteur G du support (1) avec une hauteur de recouvrement h2 sur la partie empâtée du support (1). La tête de plaque comporte une zone d'épaisseur rétrécie (4, 5, 8) comportant une partie comprimée au maximum (5, 8) et une partie de transition (4) entre cette partie comprimée au maximum et le reste de l'électrode d'épaisseur e2 . Une partie de cette tête de plaque forme une queue (5) de connexion. Le procédé d'obtention consiste en un colaminage des trois couches de mousse métallique de la tête de plaque, puis en une découpe des plaques, de façon à obtenir la queue de connexion (5).

SYNTHETIC MAMMAL OF ALPHA-N-ACETYL GLUCOSAMINIDASE AND GENETIC SEQUENCES THEREFOR

Electrode plate for an electrochemical cell and having a metal foam type support, and a method of manufacturing such an electrode plate

A method for forming an electrode plate which includes an active portion pasted with active material and a plate head which includes a connection tab. The plate head is constituted by the same metal foam as the plate support, but the density of the metal foam in the plate head is not less than 2.5 times the density of the metal foam in the remainder of the electrode plate, the higher density of the plate head coming from an operation in which the foam of the support is compressed, the tab of the plate head emerging from the middle of the thickness of the plate and being derived from compression of the support in two directions: compression firstly in the direction of its height; and compression secondly in the direction of its thickness. Such an electrode plate is made from a plate of metal foam whose top edge is compressed so as to form the plate head. Compression takes place in the height direction and then in the thickness direction for the tab, and for the remainder of the length of the electrode, compression takes place at least in the height direction.

Underwater excavation apparatus

Separator apparatus

A separator apparatus (10), such as a separator apparatus for use with an underwater excavation apparatus (5), is configured to receive a mixture of fluid and solids from an underwater excavation apparatus (5). The separator apparatus (10) includes at least one separation arrangement or means. The separation arrangement or means is configured to separate at least a portion or part of the solids from a mixture of fluid and solids passing or flowing in or through the separator apparatus (10).

Process for producing metallic iron concentrates and titanium oxide concentrates from titaniferous ores

Improved turbine

An improved turbine or motor, such as a fluid or liquid driven turbine or motor or hydraulic turbine or motor, or downhole turbine which may find use in the oil/gas and geothermal industries. The turbine or motor (5) provides a fluid passage comprising at least one portion or zone arranged to cause a drive fluid to be moved or diverted, such as at least partly radially. The turbine or motor (5) may comprise a rotor (25) comprising at least one rotor blade (15) extending within the fluid passage. The turbine or motor may comprise a stator (30) comprising at least one stator blade (20) extending within the fluid passage. The stator (30) may comprise or define at least part of the at least one portion or zone configured or arranged to cause the fluid to be moved in or diverted from an at least part axial path to an at least part radial path or radially inward path.

Flavouring agents

Apparatus and method for treating work pieces

Method and apparatus for composite user interface generation

A system for directing messages between a composite user interface and at least one source application. A message is to be directed to a predetermined set of services, each service executes a command specified by the message and the message comprises details of the predetermined set of services. Each service in the predetermined set of services uses said details to determine whether the message should be sent to another service, and if it is determined that the message should be sent to another service transmits the message to an appropriate service.

Synthetic alpha-l-iduronidase and genetic sequences encoding same

The present invention relates generally to .alpha.-L--iduronidase and to genetic sequences encoding same. More particularly, the present invention provides an is-olated nucleic acid molecule comprising a sequence of nucleotides which encodes or are complementary to a sequence which encodes a mammalian .alpha.-L-iduronidase or fragment or derivative thereof and to the recombinant enzyme encoded thereby. These molecules are useful in the investigation, diagnosis and treatment of subjects suspected of or suffering from .alpha.-L-iduronidase deficiency.

Adjustable sprinkler head riser

An apparatus for lengthening an extendible pipe comprised of first and second pipe portions having an interior includes a cylinder having an end wall and an open end connected to the first pipe portion. A piston is received in slidable and sealable engagement with the cylinder and is connected to the second pipe portion. The piston, cylinder and end wall define a chamber that is physically isolated from the interior of the pipe. Introduction of a control fluid into the chamber displaces the piston relative to the cylinder so as to lengthen the pipe. The apparatus above may be applied to a sprinkler head riser apparatus and buried as part of an in-ground sprinkler system.

Apparatus and method for loading tufts into a tuft carrier

A tuft carrier loading apparatus for load individual tufts into tuft retention sites spaced along an elongate tuft carrier, the apparatus including: guide means for guiding longitudinal movement of the tuft carrier (9) along a path of travel; a plurality of individually selectively operable tuft forming means (50) spaced along said path of travel; each tuft forming means being operable when selected to feed an individual tuft to a tuft retention site on said carrier; drive means (70) drivingly connected to the carrier (9) for moving the carrier along said path of travel, the drive means being operable to intermittently move the carrier through a series of successive positions whereat predefined tuft retention sites (9a) are moved temporarily into registry with each tuft forming means (50); and control means (60) for controlling selection of the tuft forming means, the control means being operable to actuate selected tuft forming means to feed tufts to those sites in registry with the selected tuft forming means whilst the carrier is located at each successive position.

Transportable building apparatus incorporating cargo shipping container

Speed governor

The present invention provides a speed governor (5) suitable for use in a fluid driven down-hole tool (3). The speed governor comprises an actuator (7) operatively coupled to a motive fluid flow control valve (6). The actuator is and arranged so as to be activatable, directly or indirectly, in response to the running speed of the tool (3), for opening of the control valve (6) with increasing rotational speed of the motor (3) above a predetermined speed limit thereby to limit the rotational speed of the downhole tool (3).

Power generator and turbine unit

Underwater power generator or turbine unit ( 2; 102; 202; 302; 402 ) comprises a first housing part ( 4; 104; 204; 304 P, a second body part ( 6; 106, 206, 306, 406 ) and means for connecting the first and second housing parts ( 4, 6; 104, 106; 204, 206; 304, 306; 404; 406 ). The connecting means ( 8; 108; 208; 308 ) comprise a plurality of bars ( 22; 122; 222; 322 ). The generator ( 2; 102; 202; 302 ) comprises a base ( 28; 128; 228; 328 ), having three logs ( 30, 32, 130, 132, 134; 230, 232,234;330, 332, 334; 430, 432, 434 ). The generator ( 2; 102; 202; 302, 402 ) and flow channel ( 44; 104; 204, 304 ) having first and second ends, the legs ( 30, 32,34; 130, 132, 134; 230, 232, 234, - 330, 332, 334; 430, 432, 434 ) having provided longitudinally outwardly of the ends and/or transversely outwardly of sides of the flow channel ( 44; 104; 204; 304 ).

Merry-go-round.

Magnetic base tool support

Electrode plate with a metal foam type support for an electrochemical generator and method for manufacturing such an electrode plate.

La plaque d'électrode (12) comporte une partie active (E) empâtée de matière active et une tête de plaque (2, 3, 11) comportant une queue de connexion (3). La tête de plaque est constituée par la mousse métallique elle-même du support de plaque et sa densité, par unité de surface de la mousse métallique, est au moins 2,5 fois celle de la mousse métallique du reste de la plaque d'électrode, la densité supérieure de la tête de plaque provenant d'une opération de compression de la mousse du support, la queue (3) de la tête de plaque émergeant du milieu de l'épaisseur (e2 ) de la plaque et provenant d'une compression du support dans deux directions, une première compression dans le sens de sa hauteur et une deuxième compression dans le sens de son épaisseur. Une telle plaque d'électrode est fabriquée à partir d'une plaque de mousse métallique dont le bord supérieur est comprimé de façon à former la tête de plaque. La compression a lieu dans le sens de la hauteur et ensuite dans le sens de l'épaisseur au niveau de la queue (3) et au moins dans le sens de la hauteur sur le reste de la longueur de l'électrode. The electrode plate (12) has an active part (E) pasted with active material and a plate head (2, 3, 11) comprising a connection tail (3). The plate head is formed by the metal foam itself of the plate support and its density, per unit area of the metal foam, is at least 2.5 times that of the metal foam of the rest of the electrode plate , the higher density of the plate head coming from a compression operation of the support foam, the tail (3) of the plate head emerging from the middle of the thickness (e2) of the plate and coming from a compression of the support in two directions, a first compression in the direction of its height and a second compression in the direction of its thickness. Such an electrode plate is made from a metal foam plate whose upper edge is compressed so as to form the plate head. The compression takes ...

O,O'-Amidomalonate and N,O-Amidomalonate platinum complexes

The present invention relates to amidomalonate O,O′—Pt and N,O—Pt chelates and methods of preparing them in essentially pure form.

Apparatus and method for treating work pieces

ABSTRACT APPARATUS AND METHOD FOR TREATING WORK PIECES Apparatus for treating a plurality of work pieces at spaced apart treatment stations arranged around a circle comprises a conveyor that is a horizonatal ring and that is mounted on supports for rotation about its vertical axis by a drive, and hangers mounted on the ring and including reciprocating means by which a work piece may be lowered into or raised from a treatment station. The apparatus is useful for conducting inspection penetrant treatment processes and other processes.

Power generator and turbine unit

Process for beneficiating titaniferous ores

Sizing tag

An information displaying arrangement and method for items of soft-goods displayed in a stack, uses a band engaged around each item and spanning an edge of the item, and a tag having a pair of slots with the tag being threaded on the band which extends through the slots. The tag is at the edge of the item, so that the information printed on the tag is visible at the edge even with the item in a stack of such items.

Underwater power generator

Adjustable sprinkler head riser with cushioning region

An apparatus for changing a length of a pipe, the pipe including first and second pipe portions each having an interior, includes a cylinder having a first end wall and an open end, the cylinder being connectable to the first pipe portion. The apparatus also includes a piston having a second end wall, the piston being receivable in slidable and sealable engagement with the cylinder, the piston being connectable to the second pipe portion, wherein the cylinder and the second end wall define a chamber physically isolated from the interiors of the first and second pipe portions, the chamber being adapted to receive a control fluid for displacing the piston relative to the cylinder to vary a distance between the first and second pipe portions while permitting fluid communication between the first and second pipe portions, the chamber including a cushioning region in communication with the chamber.

AROMATING MATERIALS

Modified lacz gene

A modified LacZ gene encoding a bacterial β-galactosidase enzyme. The lac Z gene is modified by altering one or more of the following: one or more ATTTA motifs; one or more cryptic splice acceptor motifs; and one or more palindromic motifs. Preferably more than one of these is altered. In addition codon usage of the modified LacZ gene is altered so as to have a decrease in the proportion of codons that are proportionately less represented in mammalian genes relative to the wild type LacZ gene. Preferred forms of the modified LacZ gene provides for greatly enhanced detectability in mammalian cells.

Separator apparatus

A separator apparatus (10), such as a separator apparatus for use with an underwater excavation apparatus (5), is configured to receive a mixture of fluid and solids from an underwater excavation apparatus (5). The separator apparatus (10) includes at least one separation arrangement or means. The separation arrangement or means is configured to separate at least a portion or part of the solids from a mixture of fluid and solids passing or flowing in or through the separator apparatus (10).

Reduced electrode electrocardiography system

Electrocardio-graphic (ECG) signals such as the standard 12-lead are synthesized from a novel reduced electrode set. Signals are received from a group of electrodes connected to predetermined locations on a human body, and deriving at least one further ECG signal using predetermined transformation(s) (130) on said first set of ECG signals. This forms a desired set of signals. The group of electrodes may comprise the standard 12 lead electrode sites V2 and V5 plus one electrode positioned substantially level with V5 on the right anterior axillary line, and a further electrode on each of the right hand side and left hand side of the body. In an alternative arrangement the electrode position V2 is replaced by an electrode position Vc on the sternum directly between the standard electrode sites V1 and V2. Also disclosed is a method of improving accuracy of synthesized signals by detecting body posture and modifying the transformations.

Improvements in and relating to underwater excavation apparatus.

Se describe un aparato de excavación (5), tal como un aparato de excavación subacuática, que tiene medios para producir, durante el uso, al menos un vórtice, espiral o flujo turbulento en un flujo de fluido laminar, por ejemplo, agua. El aparato de excavación (5) comprende un rotor (10) que tiene un eje de rotación del rotor (A), en el que, durante el uso, el flujo de fluido que pasa o atraviesa el rotor (10) forma un primer ángulo (a) desde el eje de rotación (A). El aparato de excavación (5) comprende el rotor (5) y un medio o una disposición para atenuar el par motor reactivo en el aparato (5) causado por la rotación del rotor (10), durante el uso. El flujo turbulento se provee dentro, tal como dentro de una sección transversal del flujo laminar.

Irradiation of a polyamide composition

ABSTRACT OF THE DISCLOSURE The present invention is an irradiated article made from a composition and a method of irradiating the composition. The composition comprises a polyamide and a hindered phenol having the formula: wherein: R1 is methyl, ethyl or an alpha-branched alkyl group of from 3-10 carbons, R2 is hydrogen, methyl, ethyl or an alpha-branched alkyl group of from 3-10 carbons, x is from 2-6, n is from 2-6, it being recognized that when n is greater than one, the alkyl phenol groups can vary in structure, and z is selected from the group consisting of alkylenes, arylenes, cyanurates. esters, amines, phosphorus, oxygens, sulfur, amides wherein the basic amide structure is

Panels and methods for treatment of diffuse large b-cell lymphoma

The invention provides a molecular classifier and a targeted sequencing assay for use in characterization and treatment of diffuse large B-cell lymphoma.

Colorable mixture

Multiple potted-plant self-watering system

A multiple plant container self-watering system comprises a primary container at a first elevation and a plurality of secondary containers at different elevations, fluidly connected by means of tubing. The primary container comprises a primary outer shell that encloses a primary reservoir pot, having an expanded upper portion and a tubular lower portion, a primary wick and a primary grow pot. Each of the plurality of secondary containers comprises a secondary outer shell that encloses a secondary reservoir pot having an expanded upper portion and a tubular lower portion, a secondary wick, and a secondary grow pot. The diameter of the lower portion of the primary and secondary reservoir pot is greatly reduced in comparison to the diameter of the upper portion thereof, thereby allowing for substantially similar dry-down time for a plurality of fluidly connected plant containers at different elevations.

Diffusion membranes

Resonating electroplating anode

L'anode de plaquage électrolytique comporte une anode creuse (12) et un résonateur (14) disposé suivant la surface intérieure de l'anode creuse (12). Un liant (16) assure la liaison entre le résonateur (14) et la surface intérieure de l'anode (12). L'anode suivant l'invention est utilisée en particulier pour le plaquage électrolytique de la surface intérieure de tubes de générateurs de vapeur de réacteurs nucléaires à eau sous pression. <IMAGE> The electrolytic plating anode includes a hollow anode (12) and a resonator (14) disposed along the interior surface of the hollow anode (12). A binder (16) provides the connection between the resonator (14) and the interior surface of the anode (12). The anode according to the invention is used in particular for electrolytic plating of the internal surface of tubes of steam generators of nuclear pressurized water reactors. <IMAGE>

O,o -amidomalonate and n,o-amidomalonate platinum complexes

Zink and sulphuric acid production

A process for increasing the filling capacity of tobacco

Plant trellis system

A plant trellis system for growing plants on hard surfaces such as patios or decks is disclosed. The system comprises a trellis base having a plurality of cutouts, a pot having a plurality of legs protruding from the bottom surface, and a plurality of wire mesh panels supported on the trellis base. The plurality of legs is inserted into the plurality of cutouts forming a firm connection between the trellis base and the pot. The trellis base further comprises a groove on each side where a base wire of the plurality of wire mesh panels is inserted. The trellis base also comprises a plurality of notches on each side to receive the vertical wires coming from the base wire. Clips are used to attach each wire mesh panel to the adjacent wire mesh panel. The system is portable and stable beyond the boundaries of the pot to support larger plants.

Transportable house

Underwater excavation apparatus

“There is disclosed an excavation apparatus (5), such as an underwater excavation apparatus, having means for producing, in use, at least one vortex, spiral or turbulent flow in a laminar flow of fluid, e.g. water. The excavation apparatus (5) comprises a rotor (10) having a rotor rotation axis (A), wherein, in use, flow of fluid passedpast or across the rotor (10) is at a first angle (α) from the axis of rotation (A). The excavation apparatus (5) comprises the rotor (5) and means or an arrangement for dampening reactive torque on the apparatus (5) caused by rotation of the rotor (10), in use. The turbulent flow is provided within, such as within a (transverse) cross-section, of the laminar flow.”

Resonating electrolytic plating anode

L'anode de plaquage électrolytique comporte une anode creuse (12) et un résonateur (14) disposé suivant la surface intérieure de l'anode creuse (12). Un liant (16) assure la liaison entre le résonateur (14) et la surface intérieure de l'anode (12). L'anode suivant l'invention est utilisée en particulier pour le plaquage électrolytique de la surface intérieure de tubes de générateurs de vapeur de réacteurs nucléaires à eau sous pression. The electrolytic plating anode includes a hollow anode (12) and a resonator (14) disposed along the interior surface of the hollow anode (12). A binder (16) provides the connection between the resonator (14) and the interior surface of the anode (12). The anode according to the invention is used in particular for electrolytic plating of the internal surface of tubes of steam generators of nuclear pressurized water reactors.

Reversible film for motion picture apparatus

Labelling machines

A labelling machine has a push button switch, actuation of which causes a label to be printed by a thermographic printing head with selected data which has been stored in a microprocessor by operation of a keyboard. The printed label is fed by an electrically powered drive mechanism controlled by the microprocessor to a dispensing position from which the label can be applied to an article and a further label is advanced from a supply to the printing head. The label supply is a continuous strip of separated labels with self-adhesive covered by a backing strip which is peeled away as the printed label reaches the dispensing position. Spaced optically or magnetically detectable markings on the label strip are detected in the machine to provide signals to the microprocessor for obtaining registration of each label with the printing head.

Dual propeller and engine drive system for aircraft

An aircraft drive system having two propellers, each of which is driven independently by a drive belt which is connected to a separate engine. The engines are mounted in cantilever fashion in a spaced relationship on a hollow sleeve. The sleeve is attached by a pair of spaced brackets to the frame of the aircraft. A shaft is rotatably telescopically mounted within the sleeve by bearings located on the ends of the sleeve. A pulley is fixedly mounted on one end of the shaft and is driven by one of the engines for rotating one of the propellers which is fixed on the other end of the shaft. Another pulley is rotatably mounted by bearings on the sleeve and is driven by a drive belt connected to the second engine. The second propeller is telescopically located about the sleeve adjacent the first propeller and is firmly connected to the second pulley which rotates said second propeller completely independent of the first propeller and in an opposite direction than the first propeller. The sleeve which is attached to the aircraft frame provides the entire support for the two drive engines, pulleys, propellers and associated drive belts.

Adjustable sprinkler head riser with cushioning region.

Un aparato para cambiar una longitud de una tubería, la tubería incluye una primera y segunda partes de la tubería cada una teniendo un interior, incluye un cilindro que tiene una primera pared de extremo y un extremo abierto, el cilindro siendo capaz de conectarse a la primera parte de la tubería. El aparato también incluye un pistón que tiene una segunda pared de extremo, el pistón siendo capaz de recibir en un enganche deslizable y capaz de sellarse con el cilindro, el pistón siendo conectado a la segunda parte de la tubería, en donde el cilindro y la segunda pared de extremo definen una cámara físicamente aislada de los interiores de la primera y segunda partes de la tubería, la cámara siendo adaptada para recibir un fluido de control para desplazar al pistón con relación al cilindro para variar una distancia entre la primera y segunda partes de la tubería mientras que permite la comunicación fluida entre la primera y segunda partes de la tubería, la cámara incluye una región de amortiguado en comunicación con la cámara.

Continuous salt-based melting process

A continuous salt-based process is provided for melting and reclaiming aluminum from aluminum scrap containing impurities including heating a molten salt in a heat bay, mixing the heated salt with aluminum scrap or skim in a charge bay to form a molten charge mixture, separating aluminum from impurities in the charge bay by coalescing aluminum to form a molten aluminum metal pad, chlorinating a portion of the charge mixture from the charge bay to form a chlorinated salt mixture and metal chlorides, removing metal chlorides from the salt mixture, and feeding the salt mixture back to the heat bay. In one aspect, the chlorinating step of the present invention includes introducing carbon monoxide or, preferably, solid carbon to control oxide concentration. The process further comprises adding fluorides and removing metal chlorides from the salt to maintain a preferred salt composition. The metal chlorides can be removed by withdrawing volatile metal chloride gases and electrolytically reducing metal chlorides in the molten salt.

Metallic foam-support electrode plate for electrochemical generator and fabrication process of the same

La plaque d'électrode comporte une partie active, empâtée de matière active, et une tête de plaque constituée de trois couches de mousse métallique comprimées : une partie, de hauteur G, non empâtée, du support (1) de la plaque d'électrode et deux bandes de mousse métallique (2, 3) non empâtées, de hauteur R qui encadrent la partie non empâtée de hauteur G du support (1) avec une hauteur de recouvrement h2 sur la partie empâtée du support (1). La tête de plaque comporte une zone d'épaisseur rétrécie (4, 5, 8) comportant une partie comprimée au maximum (5,8) et une partie de transition (4) entre cette partie comprimée au maximum et le reste de l'électrode d'épaisseur e2. Une partie de cette tête de plaque forme une queue (5) de connexion. Le procédé d'obtention consiste en un colaminage des trois couches de mousse métallique de la tête de plaque, puis en une découpe des plaques, de façon à obtenir la queue de connexion (5). The electrode plate has an active part, pasted with active ingredient, and a plate head consisting of three layers of compressed metal foam: part of height G, not pasted, of the support (1) of the plate electrode and two strips of metal foam (2, 3) no mashed, of height R which surrounds the non-mashed part of height G of the support (1) with a covering height h2 on the pasted part of the support (1). The plate head has a narrowed thickness zone (4, 5, 8) comprising a maximum compressed part (5.8) and a part of transition (4) between this maximum compressed part and the rest of the thickness electrode e2. Part of this plate head forms a connection tail (5). The process obtained by co-laminating the three layers of metal foam of the plate head, then in a cut plates, so as to obtain the connection tail (5).

Microchannel laminated mass exchanger and method of making

The present invention is a microchannel mass exchanger (100) having a first plurality of inner thin sheets (106, 116, 200, 300) and a second plurality of outer thin sheets (110, 118, 204, 302, 504, 510). The inner thin sheets (106, 118, 200, 300) each have a solid margin (108) around a circumference, the solid margin (108) defining a slot (104, 508) through the inner thin sheet (106, 116, 200, 300) thickness. The outer thin sheets (110, 118, 204, 302, 504, 510) each have at least two header holes (112, 202) on opposite ends and when sandwiching an inner thin sheet (106, 116, 200, 300). The outer thin sheets (110, 118, 204, 302, 504, 510) further have a mass exchange medium (400, 500). The assembly forms a closed flow channel assembly wherein fluid enters through one of the header holes into the slot and exits through another of the header holes after contacting the mass exchange medium.

Microchannel laminated mass exchanger and method of making

A method of making a microchannel mass exchanger, comprising the steps of: (a) forming at least one inner sheet having a solid margin around a circumference, the solid margin defining a slot through the entire thickness of the inner sheet, (b) forming at least one outer sheet having at least two header holes positioned within the solid margin and positioned at opposite ends of a slot length, wherein the one inner sheet is placed adjacent to the outer sheet, the solid margin sealably spacing the outer sheet and the outer sheets defining at least one longitudinal wall of a flow channel having a length parallel to a sheet length, wherein a fluid enters through one of the header holes into the slot to flow in a direction parallel or longitudinal to the length of the flow channel and exits through another of the header holes; with the proviso that at least one outer sheet comprises a mass transfer medium within the solid margin; (c) stacking the at least one inner sheet in contact with the at least one outer sheets into a stack and placing an end block or outer sheet on the at least one inner sheet as a pre-bonded assembly; and (e) bonding the pre-bonded assembly into a microchannel mass exchanger.

Compositions for improving the organoleptic qualities of cooked foodstuffs

Compositions for generating a cooked flavor in a foodstuff, comprising specified flavor precursors that react on heating to generate the flavor and maintain a reactive association after inclusion in the foodstuff. The compositions may include combination of a sulphur source, e.g. hydrogen sulphide, methane thiol, a sulfur-containing amino acid, thiamine, cystine, sodium sulphide, ammonium sulphide, ammonium polysulphide, onions, garlic, shallots, eggs, methionine, and mixtures thereof, and at least one reductone, e.g. a furanone, a ketone, a pyrone, an aldehyde, a carbonyl compound, isomaltol, maltol, pyruvaldehyde, hydroxyacetone, 3-deoxyglucosone, 5-hydroxy-5,6-dihydromaltol, 2,3-butanedione, 3-hydroxy-2-butanone, a process flavor, cooked vegetable concentrates, soy sauce, and mixtures thereof.

Roasting process in the direct reduction of iron oxide-containing ore

ABSTRACT OF THE DISCLOSURE A roasting process for the direct reduction of ores containing iron oxides which process comprises the following steps in sequence; 1. forming core pellets comprising finelyu ground ore; 2. coating the core pellets with a coke precursor so that the ratio of skin thichness of coke precursor to the diameter of the core pellets is in the range from 0.1:20 to 1:2. 3. heating the coated pellets in a substantially non-oxidizing atmosphere to a temperature below 1200°C. but high enough to cause the coke precursor to form a coke skin around the core pellet; wherein the coke precursor comprises from 5 to 25% w/w of a halide salt.

Leg Floatation Assist Swimming Trouser

Flavouring agents

Compositions for generating flavours in foodstuffs, foodstuffs incorporating such compositions and processes for producing them. In particular, compositions for generating cooked (e.g. cooked meat) flavours in a foodstuff in situ, which compositions comprise flavour precursors which react on heating to generate the flavours.

Reduced electrode electrocardiography system

Electrocardiographic (ECG) signals such as the standard 12-lead are synthesised from a novel reduced electrode set. Signals are received from a group of electrodes connected to predetermined locations on a human body, and deriving at least one further ECG signal using predetermined transformation(s) (130) on said first set of ECG signals. This forms a desired set of signals. The group of electrodes may comprise the standard 12 lead electrode sites V2 and V5 plus one electrode positioned substantially level with V5 on the right anterior auxiliary line, and a further electrode on each of the right hand side and left hand side of the body. In an alternative arrangement the electrode position V2 is replaced by an electrode position Vc on the sternum directly between the standard electrode sites VI and V2. Also disclosed is a method of improving accuracy of synthesised signals by detecting body posture and modifying the transformations.

Glycosylation variants of iduronate 2-sulfatase

The present invention provides a highly glycosylated iduronate-2-sulfatase enzyme comprising an iduronate-2-sulfatase polypeptide with at least 5 kilodalton (kDa) more sugar than iduronate-2-sulfatase purified from a natural source, e.g. human liver. The present invention also provides an enzymatically active polypeptide fragment or variant of such a highly glycosylated iduronate-2-sulfatase. The present invention further provides an isolated nucleic acid encoding iduronate-2-sulfatase, as well as an expression vector, a host cell and a method for producing the present highly glycosylated iduronate-2-sulfatase enzyme. In one embodiment the present invention is directed to a method for producing a glycosylated iduronate-2-sulfatase enzyme which comprises culturing a host cell containing a nucleic acid encoding an enzymatically active iduronate-2-sulfatase polypeptide wherein the host cell glycosylates the polypeptide to a greater degree than a native iduronate-2-sulfatase polypeptide expressed by a natural human liver cell.

Phagemid display system

Improvements in and relating to underwater excavation apparatus

There is disclosed an underwater excavation apparatus (5) comprising: means (10) for disturbing or excavating an underwater location, comprising mass flow excavation means (20); and means (15) for extracting or sucking excavated material from the location to another location comprising further mass flow means (25). Means (30) to restrict spoil and/or direct spoil to the suction means (25) are provided and comprises a baffle (35) provided within a cavity (45) of a housing (40) having an open base (60). An outlet (105) of the mass flow means (20) and an inlet (110) of the suction means (25) are located within the housing (40), while an inlet (100) of the mass flow means (20) and an outlet (115) of the suction means (25) are located external of the housing (40).

Adjustable sprinkler head riser with cushioning region

An apparatus for changing a length of a pipe, the pipe including first and second pipe portions each having an interior, includes a cylinder having a first end wall and an open end, the cylinder being connectable to the first pipe portion. The apparatus also includes a piston having a second end wall, the piston being receivable in slidable and sealable engagement with the cylinder, the piston being connectable to the second pipe portion, wherein the cylinder and the second end wall define a chamber physically isolated from the interiors of the first and second pipe portions, the chamber being adapted to receive a control fluid for displacing the piston relative to the cylinder to vary a distance between the first and second pipe portions while permitting fluid communication between the first and second pipe portions, the chamber including a cushioning region in communication with the chamber.

Methods of inhibiting bacterial virulence and compounds relating thereto

The present invention relates to compounds of formula (III) (see formula III) and methods for the treatment of bacterial infections. Because their mechanism of action does not involve killing of bacteria or inhibiting their growth, the potential for these compounds to induce drug resistance in bacteria is minimized. Through inhibiting bacterial virulence, the present invention provides a novel means of treating bacterial infections.

An improved building panel

Improvements in and relating to underwater excavation apparatus

There is disclosed an excavation apparatus (5), such as an underwater excavation apparatus, having means for producing, in use, at least one vortex, spiral or turbulent flow in a laminar flow of fluid, e.g. water. The excavation apparatus (5) comprises a rotor (10) having a rotor rotation axis (A), wherein, in use, flow of fluid passed or across the rotor (10) is at a first angle (a) from the axis of rotation (A). The excavation apparatus (5) comprises the rotor (10) and means or an arrangement for dampening reactive torque on the apparatus (5) caused by rotation of the rotor (10), in use. The turbulent flow is provided within, such as within a (transverse) cross-section, of the laminar flow.

Transportable building

Electrochemical generator with top of electrode plates separated by polymer stringer

The electrochemical generator has a number of flat electrodes (1) placed side-by-side in alternating negative and positive polarity. Each of the plates has a flat tab extending from the top to allow plates of the same polarity to be connected together by bending the tabs over so that they are in contact with each other, then joining them. To keep the tops of the plates separated during bending of the tabs, a stringer (7) made of a polymer material is placed over the top edge of the plates. The polymer material may be self adhesive or may carry a thermofusible adhesive.

Improvements in and relating to underwater excavation apparatus

Panels and methods for treatment of diffuse large b-cell lymphoma

The invention provides a molecular classifier and a targeted sequencing assay for use in characterization and treatment of diffuse large B-cell lymphoma.

Assieme di untensile brocciatore avente inserti sostituibili di carburo.

Energieerzeuger und turbineneinheit

Compositions and methods for characterizing lymphoma and related conditions

The invention provides compositions and methods useful in characterizing and/or treating classical Hodgkin's Lymphoma and/or primary mediastinal B-cell lymphoma (PMBL). In embodiments, the characterization is carried out using a biological sample comprising circulating tumor DNA (ctDNA) from a subject.

Improvements in and relating to underwater excavation apparatus

Underwater excavation apparatus

There is disclosed an excavation apparatus ( 5 ), such as an underwater excavation apparatus, having means for producing, in use, at least one vortex, spiral or turbulent flow in a laminar flow of fluid, e.g. water. The excavation apparatus ( 5 ) comprises a rotor ( 10 ) having a rotor rotation axis (A), wherein, in use, flow of fluid past or across the rotor ( 10 ) is at a first angle (a) from the axis of rotation (A). The excavation apparatus ( 5 ) comprises the rotor ( 5 ) and means or an arrangement for dampening reactive torque on the apparatus ( 5 ) caused by rotation of the rotor ( 10 ), in use. The turbulent flow is provided within, such as within a (transverse) cross-section, of the laminar flow.

Cleat or similar article

Chock or similar article

Improved methods for neoplasia detection from cell free dna

The invention features compositions and methods that are useful for determining the fraction of tumor-derived DNA (tumor fraction; TF) in cell free DNA (cfDNA). The methods involve calculating the fraction of tumor-derived DNA in the cfDNA using a combination of copy number alteration data and fragment length distribution data.