05-06-2013 дата публикации
Номер: CN103130837A
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The invention belongs to the phosphorous chemical probe technology and in particular relates to a water-soluble cationic phosphorous iridium complex as well as a preparation method of the complex and an application of the complex in cell fluorescence labeling and preparing photosensitizer in the photodyrnamic therapy. The preparation method of the water-soluble cationic phosphorous iridium complex comprises the following steps of: adding organic solvent to a mixture of 2-(4-tribromophenyl) pyridine iridium dichloride-bridged complex and 3,8-phenanthroline dibromide; obtaining 3,8- phenanthroline iridium dibromide-2-tribromophenyl pyridine complex through heating up, stirring, spin-drying and separating of the mixture; adding the prepared complex, N-(4-(5,5-dimethyl-1,3,2-dioxaborinane cyclohexyl-2-group)- phenyl)-N-phenylaniline and catalyst to a sodium carbonate solution and dimethyl formamide to obtain phosphorous iridium complex through heating up, stirring, extracting, drying, filtering ...
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