02-03-2017 дата публикации
Номер: US20170059575A1
Принадлежит:
Compositions are provided comprising water-stable semi-conductor nanoplatelets encapsulated in a hydrophilic coating further comprising lipids and lipoproteins. Uses include biomolecular imaging and sensing, and methods of making comprise: colloidal synthesis of CdSe core NPLs; layer-by-layer growth of a CdS shell; and encapsulation of CdSe/CdScore/shell NPLs in lipid and lipoprotein components through an evaporation-encapsulation using zwitterionic phospholipids, detergents, and amphipathic membrane scaffold proteins. 1. A lipoprotein nanoplatelet composition comprising semi-conductor nanoplatelets (NPLs) encapsulated in a hydrophilic coating further comprising lipids and lipoproteins.2. A composition according to wherein the nanoplatelets are colloidally stable in aqueous solution.3. A composition according to wherein the lipid is a phospholipid.4. A composition according to wherein the hydrophilic coating is a monolayer coating.5. The composition of claim 2 , wherein the nanoplatelets comprise cores and shells claim 2 , each of which cores and shells comprise a semiconductor material selected from groups II-VI claim 2 , III-V claim 2 , IV-VI claim 2 , CIGS claim 2 , and IV claim 2 , and their alloys.6. The composition of claim 5 , wherein the nanoplatelets comprise a CdSe core.7. The composition of claim 6 , wherein the nanoplatelets comprise a CdS shell.8. The composition of wherein the nanoplatelets are in the general shape of a rectangular cuboid.9. The composition of claim 8 , wherein the nanoplatelets have a thickness from about 1 nm to about 7 nm claim 8 , a length from about 5 nm to about 1000 nm claim 8 , and a width of from about 5 nm to about 1000.10. The composition of claim 8 , wherein the nanoplatelets have a thickness from about 1 nm to about 7 nm claim 8 , a length from about 10 nm to about 500 nm claim 8 , and a width of from about 10 nm to about 200.11. The composition of claim 8 , wherein the nanoplatelets have a thickness from about 1.2 nm to ...
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