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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 21. Отображено 21.
17-02-2004 дата публикации

Method for coating implantable devices

Номер: US0006692834B1
Принадлежит: Medtronic, Inc., MEDTRONIC INC, MEDTRONIC, INC.

Coating an implantable device, such as micro electromechanical devices, is highly desirable to protect the implantable device from corrosion. A coating method includes depositing, preferably by plasma glow discharge, a reactant monomer on at least one surface of an implantable device, preferably at ambient temperature. The method will likely decrease the manufacturing time required for assembling such devices because completely assembled devices can be coated.

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03-07-2001 дата публикации

Extractable implantable medical lead

Номер: US0006256542B1
Принадлежит: Medtronic, Inc., MEDTRONIC INC, MEDTRONIC, INC.

A medical electrical lead with a tip-ring assembly optimized to resist damage during extraction. The lead includes an elongated plastic tube and at least two elongated conductors mounted in the plastic tube. A tip-ring assembly is mounted to the distal end of the tube, the tip-ring assembly including a ring electrode coupled to one of the conductors, a tip electrode located distal to the ring electrode and coupled to another of the conductors and two molded plastic components separately fabricated of a plastic harder than the plastic tube, adhered to one another and together defining a circumferential groove in which the ring electrode is located and mechanically coupled to the tip electrode. The tip electrode may be provided with a proximally extending electrode shank covered by a tine sleeve which is fabricated of a plastic softer than the molded plastic components and is adhered to more distally located molded plastic component. The more distally located molded plastic component preferably ...

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17-07-2001 дата публикации

Medical electrical lead having controlled texture surface and method of making same

Номер: US0006263249B1
Принадлежит: MEDTRONIC INC., MEDTRONIC INC, MEDTRONIC, INC.

An elongate elastomeric structure having controlled surface texture. Plasma deposition is used to create controlled features, such as ridges, on the external surface of an elongate elastomeric surface, such as the external surface of silicone tubing. The invention has particular applicability in the medical device field, such as the fabrication of implantable leads, catheters, and medical devices incorporating them.

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25-03-2014 дата публикации

Antimicrobial compounds having protective or therapeutic leaving groups

Номер: US0008679518B2

Antimicrobial compounds, such as silanol or alcohol, include a protecting or leaving group that can protect the compound from degradation during the process of preparing a medical device containing the compound or reduce the volatility of the compound relative to its counterpart without the leaving group. Nearly any hydrolysable leaving group may be employed. The leaving group may be an agent that may serve a therapeutic function in addition to protecting or retaining the antimicrobial agents.

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02-01-2014 дата публикации

DRUG-ELUTING POLYMER COATED IMPLANTABLE ELECTRODE

Номер: US20140005762A1
Принадлежит: MEDTRONIC, INC.

An electrode of an implantable medical lead is coated with a polymeric composition that includes (i) a terpolymer formed from monomer subunits consisting essentially of vinyl acetate, alkyl methyl acrylate and n-vinyl pyrrolidone; (ii) a copolymer formed from monomer subunits consisting essentially of vinyl acetate and alkyl methacrylate; and (iii) polyvinyl pyrrolidone. The coating does not substantially adversely affect impedance properties of the electrode. 1. An implantable medical lead comprising:an electrode configured to contact tissue when implanted;a contact electrically coupled to the electrode, wherein the contact is configured to electrically couple the lead to a medical device; and (i) a terpolymer formed from monomer subunits consisting essentially of vinyl acetate, alkyl methyl acrylate and n-vinyl pyrrolidone;', '(ii) a copolymer formed from monomer subunits consisting essentially of vinyl acetate and alkyl methacrylate; and', '(iii) polyvinyl pyrrolidone,, 'a coating on the electrode, the coating comprising a polymer composition that includes'}wherein the coating does not substantially adversely affect impedance properties of the electrode.2. The implantable medical lead of claim 1 , wherein the polymer composition comprises from about 60 to about 70 weight percent of the terpolymer claim 1 , from about 20 to about 30 weight percent of the copolymer claim 1 , and from about 5 to about 15 weigh percent of the polyvinyl pyrrolidone.3. The implantable medical lead of claim 1 , wherein the polymer composition comprises about 63 weight percent of the terpolymer claim 1 , about 27 weight percent of the copolymer claim 1 , and about 10 weight percent of the polyvinyl pyrrolidone.4. The implantable medical lead of claim 1 , wherein the relative mole percent of the monomer subunits of the terpolymer comprises from about 2% to about 30% vinyl acetate claim 1 , from about 40% to about 77% alkyl methyl acrylate claim 1 , and from about 15% to about 30% n-vinyl ...

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21-06-2012 дата публикации

ANTIMICROBIAL COMPOUNDS HAVING PROTECTIVE OR THERAPEUTIC LEAVING GROUPS

Номер: US20120157373A1
Принадлежит: MEDTRONIC, INC.

Antimicrobial compounds, such as silanol or alcohol, include a protecting or leaving group that can protect the compound from degradation during the process of preparing a medical device containing the compound or reduce the volatility of the compound relative to its counterpart without the leaving group. Nearly any hydrolysable leaving group may be employed. The leaving group may be an agent that may serve a therapeutic function in addition to protecting or retaining the antimicrobial agents.

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26-07-2007 дата публикации

Modification of chemical forces of bone constructs

Номер: US2007173950A1
Принадлежит:

The present invention relates to a method for enhancing ingrowth of host bone comprising: modifying a bone graft structure to provide an ionic gradient to produce a modified bone graft structure; and implanting the modified bone graft structure. The present invention also relates to a method of enhancing the binding of growth factors and cell cultures to a bone graft structure comprising: applying ex vivo an effective quantity of an ionic force change agent to the surface of a bone graft structure to produce a binding-sensitized bone graft structure; implanting said binding-sensitized bone graft structure into a host bone; and administering to said binding-sensitized bone graft structure a molecule, a cell culture or a combination thereof.

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15-04-2003 дата публикации

Medical electrical lead having controlled texture surface and method of making same

Номер: US0006549811B2
Принадлежит: Medtronic, Inc, MEDTRONIC INC, MEDTRONIC, INC

An elongate elastomeric structure having controlled surface texture. Plasma deposition is used to create controlled features, such as ridges, on the external surface of an elongate elastomeric surface, such as the external surface of silicone tubing. The invention has particular applicability in the medical device field, such as the fabrication of implantable leads, catheters, and medical devices incorporating them.

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06-07-2010 дата публикации

Modification of chemical forces of bone constructs

Номер: US0007749555B2

The present invention relates to a method for enhancing ingrowth of host bone comprising: modifying a bone graft structure to provide an ionic gradient to produce a modified bone graft structure; and implanting the modified bone graft structure. The present invention also relates to a method of enhancing the binding of growth factors and cell cultures to a bone graft structure comprising: applying ex vivo an effective quantity of an ionic force change agent to the surface of a bone graft structure to produce a binding-sensitized bone graft structure; implanting the binding-sensitized bone graft structure into a host bone; and administering to the binding-sensitized bone graft structure a molecule, a cell culture or a combination thereof.

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12-04-2011 дата публикации

Wettable ePTFE medical devices

Номер: US0007923053B2
Принадлежит: KITCHING KATHRYN J, TAYLOR CATHERINE E

Methods are provided for surface modifying a hydrophobic polymer substrate to increase wettability comprising the steps of pre-treating the hydrophobic polymer substrate with a radio frequency (RF)-generated first plasma and a RF-generated second plasma wherein the first plasma and the second plasma are applied sequentially, coating the hydrophobic polymer substrate with a hydrophilic coating; and polymerizing the hydrophilic coating on the hydrophobic polymer substrate by exposure to a RF-generated third plasma.

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07-06-2011 дата публикации

Medical devices having textured surfaces

Номер: US0007955512B2
Принадлежит: Medtronic, Inc., MEDTRONIC INC, MEDTRONIC, INC.

Disclosed are medical devices having textured surfaces and related methods for texturing. Methods of surface texturing using gas-phase plasma provide medical devices with myriad complex surface morphologies.

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08-05-2012 дата публикации

Antimicrobial compounds having protective or therapeutic leaving groups

Номер: US0008173622B2

Antimicrobial compounds, such as silanol or alcohol, include a protecting or leaving group that can protect the compound from degradation during the process of preparing a medical device containing the compound or reduce the volatility of the compound relative to its counterpart without the leaving group. Nearly any hydrolysable leaving group may be employed. The leaving group may be an agent that may serve a therapeutic function in addition to protecting or retaining the antimicrobial agents.

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16-04-2002 дата публикации

Plasma process for surface modification of pyrolitic carbon

Номер: US0006372283B1
Принадлежит: Medtronic, Inc., MEDTRONIC INC, MEDTRONIC, INC.

The present invention provides a method for modifying a pyrolytic carbon surface to improve adhesion between it and a subsequently added polymer and/or a bio-active compound. In particular, plasma depositing an oxygen-containing, silicon-containing film forming monomer on a pyrolytic carbon surface improves adhesion of a polymer thereto, wherein the modified pyrolytic carbon surface and silicone rubber has a wet adhesion peel force greater than the wet adhesion peel force between an unmodified pyrolytic carbon and silicone rubber as measured by ASTM D 903-49 after 28 days in an aqueous environment, typically, at least 10 times greater.

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05-10-2004 дата публикации

Extractable implantable medical lead

Номер: US0006801809B2
Принадлежит: Medtronic, Inc., MEDTRONIC INC, MEDTRONIC, INC.

A medical electrical lead with a tip-ring assembly optimized to resist damage during extraction. The lead includes an elongated plastic tube and at least two elongated conductors mounted in the plastic tube. A tip-ring assembly is mounted to the distal end of the tube, the tip-ring assembly including a ring electrode coupled to one of the conductors, a tip electrode located distal to the ring electrode and coupled to another of the conductors and two molded plastic components separately fabricated of a plastic harder than the plastic tube, adhered to one another and together defining a circumferential groove in which the ring electrode is located and mechanically coupled to the tip electrode. The tip electrode may be provided with a proximally extending electrode shank covered by a tine sleeve which is fabricated of a plastic softer than the molded plastic components and is adhered to more distally located molded plastic component. The more distally located molded plastic component preferably ...

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27-09-2007 дата публикации

MEDICAL DEVICES HAVING TEXTURED SURFACES

Номер: US2007225785A1
Принадлежит:

Disclosed are medical devices having textured surfaces and related methods for texturing. Methods of surface texturing using gas-phase plasma provide medical devices with myriad complex surface morphologies.

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04-10-2011 дата публикации

Wettable ePTFE medical devices

Номер: US0008029562B2
Принадлежит: Medtronic, Inc., MEDTRONIC INC, MEDTRONIC, INC.

Methods are provided for surface modifying a hydrophobic polymer substrate to increase wettability comprising the steps of pre-treating the hydrophobic polymer substrate with a radio frequency (RF)-generated first plasma and a RF-generated second plasma wherein the first plasma and the second plasma are applied sequentially, coating the hydrophobic polymer substrate with a hydrophilic coating; and polymerizing the hydrophilic coating on the hydrophobic polymer substrate by exposure to a RF-generated third plasma.

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27-04-2017 дата публикации

MASSAGING LACTATION ASSISTIVE DEVICE

Номер: US20170112983A1
Принадлежит:

Disclosed are lactation assistive devices. The lactation assistive device may include a stimulation component and a controller. The stimulation component may include electrical components or mechanical components to stimulate a breast. The stimulation component may be sized to fit within a garment worn about the breast and may define an opening to be located proximate a nipple of the breast when the garment is worn. The controller may be configured to control stimulation of the breast by the stimulation component. 1. A lactation assistive device comprising:an electrode array sized to fit within a garment worn about a breast, the electrode array defining an opening to be located proximate a nipple of the breast when the garment is worn; anda controller configured to control electrical stimulation of the breast by the electrode array.2. The lactation assistive device of claim 1 , further comprising a container having a passage to be located proximate the nipple of the breast claim 1 , the container for collecting milk expressed from the breast.3. The lactation assistive device of claim 2 , wherein the container includes a first portion of a check valve and the electrode array includes a second portion of the check valve.4. The lactation assistive device of claim 1 , wherein the controller is programmed to deliver uniform excitation to the electrode array.5. The lactation assistive device of claim 1 , wherein the controller is programmed to deliver excitation to the electrode array that progresses inward from a perimeter of the electrode array toward a center of the electrode array claim 1 , the center of the electrode array located proximate the nipple of the breast.6. The lactation assistive device of claim 1 , wherein the controller is programmed to deliver excitation to the electrode array at opposing points along a diameter.7. The lactation assistive device of claim 1 , wherein the controller is programmed to provide high frequency electrical stimulation and low ...

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07-08-2008 дата публикации

Modification of chemical forces of bone constructs

Номер: WO2007087436A3

The present invention relates to a method for enhancing ingrowth of host bone comprising: modifying a bone graft structure to provide an ionic gradient to produce a modified bone graft structure; and implanting the modified bone graft structure. The present invention also relates to a method of enhancing the binding of growth, factors and cell cultures to a bone graft structure comprising: applying ex vivo an effective quantity of an ionic force change agent to the surface of a bone graft structure to produce a binding-sensitized bone graft structure; implanting said binding-sensitized bone graft structure into a host bone; and administering to said binding-sensitized bone graft structure a molecule, a cell culture or a combination thereof.

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03-01-2014 дата публикации

Drug-eluting polymer coated implantable electrode

Номер: WO2014004303A1
Принадлежит: Medtronic, Inc.

An electrode of an implantable medical lead is coated with a polymeric composition that includes (i) a terpolymer formed from monomer subunits consisting essentially of vinyl acetate, alkyl methyl acrylate and n-vinyl pyrrolidone; (ii) a copolymer formed from monomer subunits consisting essentially of vinyl acetate and alkyl methacrylate; and (iii) polyvinyl pyrrolidone. The coating does not substantially adversely affect impedance properties of the electrode.

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18-02-2010 дата публикации

Antimicrobial compounds having protective or therapeutic leaving groups

Номер: WO2010019530A1
Принадлежит: Bergan, Matthew, A., Medtronic, Inc.

Antimicrobial compounds, such as silanol or alcohol, include a protecting or leaving group that can protect the compound from degradation during the process of preparing a medical device containing the compound or reduce the volatility of the compound relative to its counterpart without the leaving group. Nearly any hydrolysable leaving group may be employed. The leaving group may be an agent that may serve a therapeutic function in addition to protecting or retaining the antimicrobial agents.

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20-06-2017 дата публикации

Drug-eluting polymer coated implantable electrode

Номер: US09682229B2
Принадлежит: MEDTRONIC INC

An electrode of an implantable medical lead is coated with a polymeric composition that includes (i) a terpolymer formed from monomer subunits consisting essentially of vinyl acetate, alkyl methyl acrylate and n-vinyl pyrrolidone; (ii) a copolymer formed from monomer subunits consisting essentially of vinyl acetate and alkyl methacrylate; and (iii) polyvinyl pyrrolidone. The coating does not substantially adversely affect impedance properties of the electrode.

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