Product demand forecasting

Embodiments include a system for forecasting demand data for new products. The system and method may include generating a phase-in group profile based on similar products. The phase-in group profile may have multiple demand profiles for low, medium and high demand variations. These demand profiles may be applied to new products in the same phase-in group to generate a forecast profile.

Dielectric resonator filter having a tunable element eccentrically located and a method of production thereof

A high-frequency filter arrangement comprising at least one filter consisting of a plurality of high-frequency inter-coupled cavities in which a locally fixed respective dielectric resonator element is disposed and in which a respective dielectric body can be modified, in order to tune the frequency of the filter, in the position thereof in relation to the dielectric resonator element. The structure of the inventive filter arrangement is simple, compact and economical and excellent filter and tuning properties are obtained by virtue of the fact that the dielectric body is arranged in an eccentric recess of the dielectric resonator element and that the dielectric body is rotatably arranged in the eccentric recess.

Tunable high-frequency filter arrangement and method for the production thereof

A high-frequency filter arrangement comprising at least one filter consisting of a plurality of high-frequency inter-coupled cavities in which a locally fixed respective dielectric resonator element is disposed and in which a respective dielectric body can be modified, in order to tune the frequency of the filter, in the position thereof in relation to the dielectric resonator element. The structure of the inventive filter arrangement is simple, compact and economical and excellent filter and tuning properties are obtained by virtue of the fact that the dielectric body is arranged in an eccentric recess of the dielectric resonator element and that the dielectric body is rotatably arranged in the eccentric recess.

Device for clamping and positioning a machine vice on the machine table of a machine tool, in particular a column drill

Method for producing a valve piece for a fuel injector, and fuel injector

The invention relates to a method for producing a valve piece (108) for a fuel injector (100), having a region on the valve piece (108) which forms a valve seat (115), wherein the valve piece (108) has, as its basic material (119), a preferably hardened steel, of which the surface, in the region forming the valve seat (115), is coated with a carbon layer (130) of greater hardness than the basic material (119). The invention makes provision for a supporting layer (120) to be formed between the basic material (119) and the carbon layer (130), wherein the hardness of the supporting layer (120) is at least equal to that of the basic material (119).

Tunable high-frequency filter arrangement and method for the production thereof

Cyclic benzimidazole derivatives as cgas inhibitors

The invention relates to compounds of formula I wherein R 1 , R 2 , R 3 , A, D, E, G, J, K and L are defined as in claim 1, and prodrugs, deuterated analogues and pharmaceutical acceptable salts thereof, for the treatment of diseases such as systemic lupus erythematosus, systemic sclerosis (SSc), interferonopathies, non-alcoholic steatohepatitis (NASH), interstitial lung disease (ILD) and idiopathic pulmonary fibrosis (IPF).

Cyclic Pyridine Derivatives as cGAS Inhibitors

The invention relates to compounds of formula Iwherein R1, R2, R3, R4, A, D, E, G, J, K and L are defined as in claim 1, and prodrugs, deuterated analogues and pharmaceutical acceptable salts thereof, for the treatment of diseases such as systemic lupus erythematosus, systemic sclerosis (SSc), interferonopathies, non-alcoholic steatohepatitis (NASH), interstitial lung disease (ILD) and idiopathic pulmonary fibrosis (IPF).

Cyclic benzimidazole derivatives as cgas inhibitors

The invention relates to compounds of formula Iwherein R1, R2, R3, A, D, E, G, J, K and L are defined as in claim 1, and prodrugs, deuterated analogues and pharmaceutical acceptable salts thereof, for the treatment of diseases such as systemic lupus erythematosus, systemic sclerosis (SSc), interferonopathies, non-alcoholic steatohepatitis (NASH), interstitial lung disease (ILD) and idiopathic pulmonary fibrosis (IPF).

Cyclic pyridine derivatives as cgas inhibitors

The invention relates to compounds of formula Iwherein R1, R2, R3, R4, A, D, E, G, J, K and L are defined as in claim 1, and prodrugs, deuterated analogues and pharmaceutical acceptable salts thereof, for the treatment of diseases such as systemic lupus erythematosus, systemic sclerosis (SSc), interferonopathies, non-alcoholic steatohepatitis (NASH), interstitial lung disease (ILD) and idiopathic pulmonary fibrosis (IPF).

PYRIDINE DERIVATIVES WITH N-LINKED CYCLIC SUBSTITUENTS AS cGAS INHIBITORS

The invention relates to new proline derivatives of formula (I) as cGAS inhibitors,whereinwherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and G are defined as in claim 1,and prodrugs or pharmaceutically acceptable salts of these compoundsfor the treatment of diseases such as systemic lupus erythematosus, systemic sclerosis (SSc), non-alcoholic steatotic hepatitis (NASH), interstitial lung disease (ILD) and idiopathic pulmonary fibrosis (IPF).