Benzenesulfonyl-chromane, thiochromane, tetrahydronaphthalene and related gamma secretase inhibitors

This invention discloses novel gamma secretase inhibitors of the formula: R 2 and R 3 , or R 2 and R 4 , or R 3 and R 4 , together with the atoms to which they are bound, can form a fused cycloalkyl or fused heterocycloalkyl ring. The cycloalkyl ring or the heterocycloalkyl ring can be optionally substituted with one or more substituents. One or more compounds of formula (I), or formulations comprising such compounds, may be useful, e.g. in treating Alzheimer's Disease.

Tricyclic heterocycles useful as dipeptidyl peptidase-iv inhibitors

The present invention is directed to novel tricyclic heterocycles of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved. I

Grid Arrays with Enhanced Fatigue Life

Reliability is improved for the mechanical electrical connection formed between a grid array device, such as a pin grid array device (PGA) or a column grid array device (CGA), and a substrate such as a printed circuit board (PCB). Between adjacent PCB pads, a spacing pattern increases toward the periphery of the CGA, creating a misalignment between pads and columns. As part of the assembly method, columns align with the pads, resulting in column tilt that increases from the center to the periphery of the CGA. An advantage of this tilt is that it reduces the amount of contractions and expansions of columns during thermal cycling, thereby increasing the projected life of CGA. Another advantage of the method is that it reduces shear stress, further increasing the projected life of the CGA. 1. An electronic assembly comprising:a printed circuit board having an array of connecting pads and a board coefficient of thermal expansion;an electronic component having a different coefficient of thermal expansion than the board coefficient of thermal expansion, an array of conducting posts connecting the electronic component to respective pads of the array of connecting pads on the printed circuit board, conducting posts of the array being angled from the electronic component to the circuit board at 20 degrees Celsius.2. The assembly of claim 1 , wherein connecting pads connected to angled posts outside of a centermost region of the electronic component have a lesser pad thickness than the connecting pads in the centered region.3. The assembly of claim 1 , wherein peripheral conducting posts of the array of conducting posts are angled outwardly from a center of the electronic component to the circuit board.4. The assembly of claim 1 , wherein the board coefficient of expansion is greater than the electronic component coefficient of thermal expansion and conducting posts of the array of conducting posts are angled outwardly from a center of the electronic component to the circuit ...

MULTI-REFLECTION MASS SPECTROMETER

A multi-reflection mass spectrometer comprising two ion-optical mirrors, each mirror elongated generally along a drift direction (Y), each mirror opposing the other in an X direction and having a space therebetween, the X direction being orthogonal to Y; the mass spectrometer further comprising one or more compensation electrodes each electrode being located in or adjacent the space extending between the opposing mirrors; the compensation electrodes being configured and electrically biased in use so as to produce, in at least a portion of the space extending between the mirrors, an electrical potential offset which: (i) varies as a function of the distance along the drift length, and/or; (ii) has a different extent in the X direction as a function of the distance along the drift length. In a preferred embodiment the period of ion oscillation between the mirrors is not substantially constant along the whole of the drift length. 1. (canceled)2. A multi-reflection mass spectrometer comprising two ion-optical mirrors , each mirror elongated generally along a drift direction (Y) , each mirror opposing the other in an X direction and having a space therebetween , the X direction being orthogonal to the Y direction;the spectrometer further comprising an ion injector located at one end of the ion-optical mirrors in the drift direction, arranged so that in use it injects ions such that they oscillate between the ion-optical mirrors, reflecting from one mirror to the other generally orthogonally to the drift direction a plurality of times, turning the ions within each mirror whilst the ions proceed along the drift direction Y;wherein a distance between subsequent points at which the ions turn in the Y-direction changes monotonously with Y during at least a part of the motion of the ions along the drift direction.3. The multi-reflection mass spectrometer of in which the mass spectrometer further comprises one or more compensation electrodes each electrode being located in or ...

MULTI-REFLECTION MASS SPECTROMETER

A multi-reflection mass spectrometer is provided comprising two ion-optical mirrors, each mirror elongated generally along a drift direction (Y), each mirror opposing the other in an X direction, the X direction being orthogonal to Y, characterized in that the mirrors are not a constant distance from each other in the X direction along at least a portion of their lengths in the drift direction. In use, ions are reflected from one opposing mirror to the other a plurality of times while drifting along the drift direction so as to follow a generally zigzag path within the mass spectrometer. The motion of ions along the drift direction is opposed by an electric field resulting from the non-constant distance of the mirrors from each other along at least a portion of their lengths in the drift direction that causes the ions to reverse their direction. 1. (canceled)2. A method of mass spectrometry comprising the steps of:injecting ions into a multi-reflection mass spectrometer comprising two ion-optical mirrors, each mirror elongated generally along a drift direction Y, each mirror opposing the other in an X direction, the X direction being orthogonal to Y direction;reflecting the ions from one mirror to the other, generally orthogonally to the drift direction, a plurality of times by turning the ions within each mirror whilst the ions proceed along the drift direction Y, wherein the distance between consecutive points in the X-direction at which the ions turn monotonously changes with Y during at least a part of the motion of the ions along the drift direction; anddetecting at least some of the ions during or after their passage through the multi-reflection mass spectrometer.3. The method of mass spectrometry of in which the multi-reflection mass spectrometer further comprises one or more electrically biased compensation electrodes extending along at least a portion of the drift direction claim 1 , each electrode being located in or adjacent a space between the mirrors.4. ...

Advanced Techniques for Machine Learning Using Sample Comparisons

Machine learning techniques can be used to train a classifier, in some embodiments, to accurately detect similarities between different records of user activity for a same user. When more recent data is received, newer data can be analyzed by selectively removing particular sub-groups of data to see if there is any particular data that accounts for a large difference (e.g. when run through a classifier that has been trained to produce similar results for known activity data from a same user). If a sub-group of data is identified as being significantly different from other user data, this may indicate an account breach. Advanced machine learning techniques described herein may be applicable to a variety of different environments. 1. A method , comprising:accessing a set of records of a plurality of activities performed by a plurality of users of an electronic service provider (ESP);training a classifier for a neural network using the set of records, wherein the classifier is trained to minimize outcome differences between sample records of the set of records that belong to a same user;using the trained classifier, by a computer system, to determine a degree of similarity between a newer set of records of a plurality of activities performed by a particular user of the ESP and an older set of records of a plurality of activities performed by the particular user; andbased on the degree of similarity, determining whether an account of the particular user appears to have been used by a different user.2. The method of claim 1 , wherein the classifier is trained to maximize outcome differences between sample of records of the set of records that belong to different users.3. The method of claim 1 , wherein the neural network is a siamese network comprising a first network and a second network.4. The method of claim 3 , wherein training the classifier comprises performing multiple iterations of feeding particular records to the first and second networks while adjusting a ...

SYSTEM AND METHOD FOR MALWARE DETECTION

Aspects of the present disclosure involve a system and method for malware detection. The system and method introduce a probabilistic model that can observe user transaction data over a predetermined window of time. Then, using posterior probability, the system can determine whether multiple users where present during the window observed. 1. A system comprising:a non-transitory memory storing instructions; and in response to a determination that a malware detection check is being performed, retrieve a user transaction log;', 'model, using a first process, a user transaction model for a first user, the user transaction model generated by a determination module in the system;', 'model, using a second process, a second user transaction model for a second user, the second user transaction model generated by the determination module in the system;', 'determine a window length and window of the user transaction log for observing user transition data, the window including a subsequence of the user transaction log; and', 'compute a posterior probability of multiuser access during the window determined., 'a processor configured to execute instructions to cause the system to2. The system of claim 1 , executing instructions further causes the system to:determine, labels for one or more parameters in the user transaction data, the labels determined using an inference on the primary user transaction model and second user transaction model and used in a computing of the posterior probability.3. The system of claim 1 , executing instructions further causes the system to:determine a first primary score for the first user;determine a second primary score for the second user; andprovide the primary score and the secondary score for use in a computing of the posterior probability.4. The system of claim 1 , wherein the user transaction data includes a transaction times and amounts for the first user during the window.5. The system of claim 1 , wherein a Hawkes process is used for the ...

Compositions and methods for treating diarrheal diseases

Provided is a composition for the treatment of diarrheal disease, comprising a polyphenol-rich extract of a mixture of 80-20% by weight of blueberry or bilberry from Vaccinium cyanococcus spp., Vaccinium myrtillis spp., or both; and 20-80% by weight of sloe berry from Prunus spinosa spp. Other compositions, and methods of making and using the compositions for the treatment of diarrheal disease are disclosed.

Grid Arrays With Enhanced Fatigue Life

Reliability is improved for the mechanical electrical connection formed between a grid array device, such as a pin grid array device (PGA) or a column grid array device (CGA), and a substrate such as a printed circuit board (PCB). Between adjacent PCB pads, a spacing pattern increases toward the periphery of the CGA, creating a misalignment between pads and columns. As part of the assembly method, columns align with the pads, resulting in column tilt that increases from the center to the periphery of the CGA. An advantage of this tilt is that it reduces the amount of contractions and expansions of columns during thermal cycling, thereby increasing the projected life of CGA. Another advantage of the method is that it reduces shear stress, further increasing the projected life of the CGA. 1. A method of assembling an electronic component onto a printed circuit board comprising:placing an array of pads on the printed circuit board;applying connective material to the pads;providing the electronic component, having an array of conducting posts, pads of the array of pads being misaligned with conducting posts of the array of conducting posts;mounting the electronic component to the circuit board with the array of conducting posts connected to the array of pads with ends of the conducting posts drawn into closer alignment with the pads, conducting posts of the array of conducting posts being angled from the electronic component to the circuit board when at 20 degrees Celsius.2. The method of claim 1 , wherein connecting pads connected to angled posts outside of a centermost region of the electronic component have a lesser pad thickness than the connecting pads in the centermost region.3. The method of claim 1 , wherein peripheral conducting posts of the array are angled outwardly from a center of the electronic component to the circuit board.4. The method of claim 1 , wherein a board coefficient of expansion is greater than an electronic component coefficient of thermal ...

Network assisted lte crs interference mitigation

An apparatus of user equipment (UE) comprises processing circuitry and memory. The processing circuitry decodes radio resource control (RRC) signaling received from an enhanced node B (eNB), wherein the RRC signaling includes an information element (IE) including information of a multi-cast broadcast single frequency network (MBSFN) subframe pattern of neighboring cells of a serving cell of the eNB. The processing circuitry initiates detection of CRS information of neighboring cells by the UE, the CRS information including one or both of physical cell identifiers (Cell IDs) and a number of CRS antenna ports (APs) of the neighboring cells; and initiates neighboring cell CRS interference mitigation (CRS-IM) using the detected CRS information and the received information of the MBSFN subframe pattern. The memory stores the information of the MBSFN subframe pattern.

Memristive neuromorphic circuit and method for training the memristive neuromorphic circuit

A neural network is implemented as a memristive neuromorphic circuit that includes a neuron circuit and a memristive device connected to the neuron circuit. A conductance balanced voltage pair is provided for the memristive device, where the conductance balanced voltage pair includes a set voltage for increasing the conductance of the memristive device and a reset voltage for decreasing the conductance of the memristive device. Either the set voltage and reset voltage, when applied to the memristive device, effects a substantially same magnitude conductance change in the memristive device over a predetermined range of conductance of the memristive device. The provided voltage pair is stored as a conductance balanced map. A training voltage based on the conductance balanced map is applied to the memristive device to train the neural network.

Memristive neuromorphic circuit and method for training the memristive neuromorphic circuit

A neural network is implemented as a memristive neuromorphic circuit that includes a neuron circuit and a memristive device connected to the neuron circuit. An input voltage is sensed at a first terminal of a memristive device during a feedforward operation of the neural network. An error voltage is sensed at a second terminal of the memristive device during an error backpropagation operation of the neural network. In accordance with a training rule, a desired conductance change for the memristive device is computed based on the sensed input voltage and the sensed error voltage. Then a training voltage is applied to the memristive device. Here, the training voltage is proportional to a logarithmic value of the desired conductance change.

System and method for identifying spam email

Disclosed herein are systems and method for spam identification. A spam filter module may receive an email at a client device and may determine a signature of the email. The spam filter module may compare the determined signature with a plurality of spam signatures stored in a database. In response to determining that no match exists between the determined signature and the plurality of spam signatures, the spam filter module may placing the email in quarantine. A spam classifier module may extract header information of the email and determine a degree of similarity between known spam emails and the email. In response to determining that the degree of similarity exceeds a threshold, the spam filter module may transfer the email from the quarantine to a spam repository.

MULTI-REFLECTION MASS SPECTROMETER

A multi-reflection mass spectrometer is provided comprising two ion-optical mirrors, each mirror elongated generally along a drift direction (Y), each mirror opposing the other in an X direction, the X direction being orthogonal to Y, characterized in that the mirrors are not a constant distance from each other in the X direction along at least a portion of their lengths in the drift direction. In use, ions are reflected from one opposing mirror to the other a plurality of times while drifting along the drift direction so as to follow a generally zigzag path within the mass spectrometer. The motion of ions along the drift direction is opposed by an electric field resulting from the non-constant distance of the mirrors from each other along at least a portion of their lengths in the drift direction that causes the ions to reverse their direction. 1. A multi-reflection mass spectrometer comprising two ion-optical mirrors , each mirror elongated generally along a drift direction (Y) , each mirror opposing the other in an X direction , the X direction being orthogonal to Y , wherein the mirrors are not a constant distance from each other in the X direction along at least a portion of their lengths in the drift direction.2. The multi-reflection mass spectrometer of further comprising an ion injector located at one end of the ion-optical mirrors in the drift direction claim 1 , the elongated ion-optical mirrors being closer together in the X direction along at least a portion of their lengths as they extend in the drift direction away from the ion injector.3. The multi-reflection mass spectrometer of claim 1 , in which the opposing mirrors are elongated generally linearly in the drift direction and are not parallel to each other.4. The multi-reflection mass spectrometer of claim 1 , in which at least one mirror curves towards the other mirror along at least a portion claim 1 , of its length in the drift direction.5. The multi-reflection mass spectrometer of claim 1 , in ...

MULTI-REFLECTION MASS SPECTROMETER

A multi-reflection mass spectrometer comprising two ion-optical mirrors, each mirror elongated generally along a drift direction (Y), each mirror opposing the other in an X direction and having a space therebetween, the X direction being orthogonal to Y; the mass spectrometer further comprising one or more compensation electrodes each electrode being located in or adjacent the space extending between the opposing mirrors; the compensation electrodes being configured and electrically biased in use so as to produce, in at least a portion of the space extending between the mirrors, an electrical potential offset which: (i) varies as a function of the distance along the drift length, and/or; (ii) has a different extent in the X direction as a function of the distance along the drift length. In a preferred embodiment the period of ion oscillation between the mirrors is not substantially constant along the whole of the drift length. 1. A multi-reflection mass spectrometer comprising two ion-optical mirrors , each mirror elongated generally along a drift direction (Y) , each mirror opposing the other in an X direction and having a space therebetween , the X direction being orthogonal to Y;the mass spectrometer further comprising one or more compensation electrodes each electrode being located in or adjacent the space extending between the opposing mirrors;the compensation electrodes being configured and electrically biased in use so as to produce, in at least a portion of the space extending between the mirrors, an electrical potential offset which:(i) varies as a function of the distance along the drift length, and/or;(ii) has a different extent in the X direction as a function of the distance along the drift length.2. The multi-reflection mass spectrometer of further comprising an ion injector located at one end of the ion-optical mirrors in the drift direction arranged so that in use it injects ions such that they oscillate between the opposing mirrors while proceeding ...

PROTECTING AGAINST MALWARE VARIANTS USING RECONSTRUCTED CODE OF MALWARE

A system for discovering programming variants. The system analyzes system calls from executing a program to generate programming code or executable for a particular OS and/or CPU that would perform the same or similar actions as the program. The code that is generated is then mutated, augmented, and/or changed to create variations of the program which still functions and/or obtains the same objectives as the original code. 1. A system , comprising:a non-transitory memory storing instructions; andone or more hardware processors coupled to the non-transitory memory and configured to read the instructions from the non-transitory memory to cause the system to perfonn operations comprising:receiving an application infected with a malicious code;determining system calls corresponding to the malicious code based on the application infected with the malicious code;generating a first programming code based on the system calls;augmenting the first programming code to create a second programming code, the second programming code being different from the first programming code; andtesting that the second programming code achieves an objective that is the same as the malicious code.2. The system of claim 1 , wherein the operations further comprise updating a malware prevention system to detect a second virus based on the second programming code.3. The system of claim 1 , wherein determining system calls corresponding to the malicious code comprises comparing a first set of system calls from running the application infected with the malicious code with a second set of system calls from running the application uninfected with the malicious code.4. The system of claim 3 , wherein the application infected with the malicious code is run in a first controlled environment.5. The system of claim 4 , wherein the application infected with the malicious code is run in a second controlled environment different from the first controlled environment.6. The system of claim 4 , wherein the ...

Wireless Power Transmitting Devices

A power system has a wireless power transmitting device and a wireless power receiving device. Coils in the transmitting device may include a circular coil overlapped by first and second rectangular coils at a charging surface. The rectangular coils each include straight segments extending over a central region of the circular coil. Control circuitry can activate the circular coil to transmit wireless power to a first type of wireless power receiving coil using vertical components of the magnetic field generated by the circular coil. The control circuitry can activate the rectangular coils to transmit wireless power to a second type of wireless power receiving coil using horizontal components of the magnetic field generated by the rectangular coils. The circular and rectangular coils wirelessly charge the power receiving device while located at the same position on the charging surface, regardless of the type of wireless power receiving coil that is used.

Sheet lighting for particle detection in drug product containers

In a method for imaging a container holding a sample, the container is illuminated with a laser sheet that impinges upon the container in a first direction corresponding to a first axis. A plane of the laser sheet is defined by the first axis and a second axis orthogonal to the first axis. The method also includes capturing, by a camera having an imaging axis that is substantially orthogonal to at least the first axis, an image of the container. The method further includes analyzing, by one or more processors, the image of the container to detect particles within, and/or on an exterior surface of, the container.

SYSTEM AND METHOD FOR COMPACT TREE REPRESENTATION FOR MACHINE LEARNING

Aspects of the present disclosure involve systems, methods, devices, and the like for generating compact tree representations applicable to machine learning. In one embodiment, a system is introduced that can retrieve a decision tree structure to generate a compact tree representation model. The compact tree representation model may come in the form of a matrix design to maintain the relationships expressed by the decision tree structure. 1. A system comprising:a non-transitory memory storing instructions; and retrieving, a file including information associated with a tree structure;', 'analyzing, the tree structure to determine a nodes on the tree structure;', 'determining, based on the analyzing, a relationship between nodes and a frequency of the nodes; and', 'generating, a compact matrix representing the relationship determined., 'a processor configured to execute instructions to cause the system to2. The system of claim 1 , wherein the information associated with the tree structure includes a decision tree format.3. The system of claim 1 , wherein the file is in the form of a text file including processes running the system.4. The system of claim 1 , wherein the determining includes determining a number of times the node is called and a relationship of the node to another node.5. The system of claim 1 , wherein the compact matrix is represented by a string of numbers where a location of each number is presentative of a cell on the matrix.6. The system of claim 5 , wherein the instructions further comprising:learning, by a machine learning model in the system, from the compact matrix; andidentifying, by the system, patterns associated with the string of numbers input.7. The system of claim 1 , wherein the file retrieved from a plurality of machines running processing in the system for compacting and monitoring information.8. The system of claim 7 , wherein monitoring includes identifying errors in a sequence received by the system from one or more external ...

Device Lifecycle Management via a Central Identity Service

Managing devices in an IoT environment. A method includes, as a result of a device being provisioned by a special-purpose solution, storing at a central unified registry a correlation of the device and the given special purpose solution. The method further includes correlating the device to a different special-purpose solution at the unified registry. As a result, the method further includes causing subsequent configuration of the device to be performed by the different special-purpose solution. 1. A computer system comprising:one or more processors; and as a result of a device being provisioned by a special-purpose solution, store at a central unified registry a correlation of the device and the given special purpose solution;', 'correlate the device to a different special-purpose solution at the unified registry; and', 'as a result, cause subsequent configuration of the device to be performed by the different special-purpose solution., 'one or more computer-readable media having stored thereon instructions that are executable by the one or more processors to configure the computer system to manage devices in an IoT environment, including instructions that are executable to configure the computer system to perform at least the following2. The computer system of claim 1 , wherein the unified registry allows devices in different locations to be managed by local special-purpose solutions to meet a predetermined latency threshold claim 1 , while still providing a central location where entities can query for information about the devices.3. The method of claim 1 , wherein the unified registry allows devices for different tenants to be managed by tenant-specific special-purpose solutions to meet a predetermined tenant data isolation threshold claim 1 , while still providing a central location where entities can query for information about the devices.4. The computer system of claim 1 , wherein the unified registry allows devices subject to different service-level ...

TRANSFERRING DIGITAL DEVICE OWNERSHIP VIA A SIGNED TRANSFER REQUEST

Transferring control over a device. A method includes, receiving a first indication, including a first verifiable token, from a first entity that at least a portion of control of a device should be relinquished by the first entity. A second indication is received from the second entity, including a second verifiable token, that the at least a portion of control should be transferred to the second entity. The first token and the second token are verified. As a result of verifying the first token and the second token, the at least a portion of control of the device is transferred from the first entity to the second entity. Transferring the at least a portion of control of the device from the first entity to the second entity includes updating the device with configuration applicable to the second entity. 1. A computer system comprising:one or more processors; andone or more computer-readable media having stored thereon instructions that are executable by the one or more processors to configure the computer system to transfer at least a portion of control over a device, including instructions that are executable to configure the computer system to perform at least the following:at a device management service, receive a first indication from a first entity that at least a portion of control of a device should be relinquished by the first entity, the first indication comprising a first verifiable token from the first entity;at the device management service, receive a second indication from the second entity that the at least a portion of control should be transferred to the second entity, the second indication comprising a second verifiable token from the second entity;at the device management service, verify the first token and the second token; andat the device management service, as a result of verifying the first token and the second token, transfer the at least a portion of control of the device from the first entity to the second entity, wherein transferring the at ...

Heating smokeable material

An apparatus comprising a heater configured to heat smokeable material to volatilize at least one component of the smokeable material, wherein the heater is elongate and comprises a plurality of independently controllable heating regions arranged sequentially along a longitudinal axis of the heater.

Enhanced real-time visual quality metric generation for video coding

This disclosure describes systems, methods, and devices related to generating visual quality metrics for encoded video frames. A method may include generating respective first visual quality metrics for pixels of an encoded video frame; generating respective second visual quality metrics for the pixels, the respective first visual quality metrics and the respective second visual quality metrics indicative of estimated human perceptions of the encoded video frame; generating a pixel block-based weight for the respective first visual quality metrics; generating a frame-based weight for the respective second visual quality metrics; and generating, based on the respective first visual quality metrics, the pixel block-based weight, the respective second visual quality metrics, and the frame-based weight, a human visual score indicative of a visual quality of the encoded video frame.

METHOD, WIRELESS COMMUNICATION STATION, AND SYSTEM FOR REDUCING DATA STARVATION

Embodiments of a wireless communication station and methods for reducing data starvation are generally described herein. In some embodiments, a wireless communications station passes data packets stored in a buffer to a higher-level medium access control (MAC) process, in sequential order based on a sequence number (SN) subfield of the data packets. A watchdog timer is activated upon encountering a missing data packet during the passing. Upon expiration of the watchdog timer, the wireless communication station transmits a delete block acknowledgment (DELBA) frame to terminate a block acknowledgment (ACK) agreement with an originator of the data packets. 1. A method to reduce data starvation in a wireless communication network , the method comprising:passing data packets stored in a buffer to a higher-level medium access control (MAC) process, the passing being performed in a sequential order based on sequence number (SN) subfields of the data packets;activating a watchdog timer upon encountering a missing data packet, the encountering being based on an inspection of the SN subfields during the passing; andtransmitting, upon expiration of the watchdog timer, a delete block acknowledgment (DELBA) frame to terminate a block acknowledgment (ACK) agreement with an originator of the data packets.2. The method of claim 1 , further comprising:receiving at least one data packet subsequent to the activation of the watchdog timer and storing the at least one data packet in the buffer;passing data packets of the buffer to the higher-level MAC process upon expiration of the watchdog timer.3. The method of claim 1 , wherein a duration for the watchdog timer is determined based on a latency tolerance of the higher-level MAC process.4. The method of claim 3 , further comprising:determining whether the buffer is empty upon encountering a missing data packet; andwherein the activating activates the watchdog timer if the determining determines that the buffer is not empty.5. The ...

System Call Vectorization

The systems and methods that detect malware from count vectors are provided. A count vector having multiple components is generated. The count vector tracks a number and types of system calls generated by a process. Each component in the count vector is mapped to a type of a system call that exists in an operating system. Multiple system calls generated by the process are received over a first time interval. Each system call is mapped to a component in the count vector. The count vectors are aggregated according to a second time interval into a vector packet. The vector packet is transmitted over a network to a malware detection system that uses the count vectors in the vector packet to determine whether the process is a malware process. 1. A system , comprising:a non-transitory memory storing instructions; and generating a count vector having a plurality of components, wherein the count vector tracks a number and types of system calls generated by a process;', 'mapping each component in the plurality of components to a type of a system call;', 'receiving a plurality of system calls generated by the process over a first time interval;', 'mapping each system call from the plurality of system calls to a component of the plurality of components in the count vector; and', 'transmitting the count vector to a malware detection module, wherein the malware detection module determines whether the process is a malware process based on the count vector., 'one or more hardware processors coupled to the non-transitory memory and configured to read the instructions from the non-transitory memory to cause the system to perform operations comprising2. The system of claim 1 , wherein the operations further comprise:aggregating the count vector with a plurality of count vectors generated for the process over a second time interval into a vector packet; andtransmitting the vector packet to the malware detection module.3. The system of claim 2 , wherein the vector packet includes a ...

Method, apparatus, and system for estimating continuous population density change in urban areas

An approach is disclosed for estimating population density change where dynamic signals are not available or are not dense enough to be representative. The approach involves, for example, determining map features of a first map space. The approach also involves identifying partitions of the first map space based on the identified partitions (i) having features that are substantially similar, and (ii) having respective change functions that are substantially similar. The approach further involves determining an estimated change function based on one or more of the respective change functions that are substantially similar and that are associated with the first map space. The approach further involves using the estimated change function for at least one partition of a second map space based on the at least one partition of the second map space and at least one map partition of the first map space having map features that are substantially similar.

ADVANCED COMPUTER SYSTEM DRIFT DETECTION

Computer system drift can occur when a computer system or a cluster of computer systems deviates from ideal and/or desired behavior. In a server farm, for example, many different machines may be identically configured to work in conjunction with each other to provide an electronic service (serving web pages, processing electronic payment transactions, etc.). Over time, however, one or more of these systems may drift from previous behavior. Early drift detection can be important, especially in large enterprises, to avoiding costly downtime. Changes in a computer's configuration files, network connections, and/or executable processes can indicate ongoing drift, but collecting this information at scale can be difficult. By using certain hashing and min-Hash techniques, however, drift detection can be streamlined and accomplished for large scale operations. Velocity of drift may also be tracked using a decay function. 1. A method to facilitate detecting system drift , comprising:performing a first scan of a plurality of configuration files corresponding to a first computer system, wherein the configuration files include information affecting one or more behaviors of the first computer system;hashing the plurality of configuration files to produce a corresponding first plurality of configuration hash strings;performing a min-Hash operation on the first plurality of configuration hash strings to produce a min-Hash signature for the first computer system, wherein the min-Hash signature includes information indicative of a status for individual ones of the plurality of configuration files corresponding to the first computer system; andtransmitting the min-Hash signature, via a network, to a monitoring system.2. The method of claim 1 , further comprising:at a time subsequent to the first scan, performing an additional scan of a subsequent plurality of configuration files corresponding to the first computer system hashing the subsequent plurality of configuration files to ...

Dibenzofurans and dibenzothiophenes

in which the occurring groups and parameters have the meanings as indicated in claim 1, to liquid-crystalline media comprising same and to high-frequency components comprising these media, especially microwave components for high-frequency devices, such as devices for shifting the phase of microwaves, in particular for microwave phased-array antennas.

SYSTEM AND METHOD FOR COMPACT TREE REPRESENTATION FOR MACHINE LEARNING

Aspects of the present disclosure involve systems, methods, devices, and the like for generating compact tree representations applicable to machine learning. In one embodiment, a system is introduced that can retrieve a decision tree structure to generate a compact tree representation model. The compact tree representation model may come in the form of a matrix design to maintain the relationships expressed by the decision tree structure. 1. A system comprising:a non-transitory memory storing instructions; and in response to a determination that new data is available for processing, retrieve a data tree structure of the new data;', 'determine, from the new data, nodes on the data tree structure, the nodes corresponding to processes running on at least one secondary machine;', 'calculate, using the data tree structure, a frequency and relationship between the nodes;', 'generate, using the frequency and relationship between the nodes, a compact tree representation model, the compact tree representation model including a matrix; and', 'process, using a machine learning technique, the compact tree representation model for pattern identification., 'a processor configured to execute instructions to cause the system to2. The system of claim 1 , executing instructions further causes the system to:input, into the system, the compact tree model, the compact tree model represented in a string format.3. The system of claim 2 , wherein the string format includes digits representing each cell in the matrix.4. The system of claim 1 , wherein the pattern identification includes a learned sequence from the processes running on the at least one secondary machine.5. The system of claim 4 , executing the instructions further causes the system to:monitor, the at least one secondary machine for correct sequence processing based on the learned sequences; andcorrect, errors identified during the monitoring.6. The system of claim 5 , wherein the errors identified include an error in the ...

Inclination-Adjustable Armrest

An inclination-adjustable armrest (10) includes a pivot bearing (12) formed at one end of the armrest, the pivot bearing defining a pivotal axis (A) for the armrest, a clamping-type locking mechanism (16) arranged on the pivotal axis and being adapted to be unlocked by a release member (20) that is rotatable about the pivotal axis, and an actuating mechanism for actuating the release member, wherein the actuating mechanism has a release lever (22) that is connected to the release member (20) and is rotatable about the pivotal axis (A) and which extends through the interior of the armrest (10) to the end of the armrest opposite to the pivot bearing (12) and exits the armrest at that opposite end.

An Additive Manufacturing Method for Precipitation-Hardened Superalloy Powdered Material

An additive manufacturing technique, wherein a first layer of powdered material is spread on a build platform, with or without a workpiece positioned therein, the build platform is in a part building module of an additive manufacturing apparatus, the powdered material is a precipitation-hardened superalloy such as a Nickel-based superalloy, for example, a Nickel-based superalloy having a percentage by volume of gamma prime phase equal to or greater than 45 percentage by volume, the first layer forms at least a part of a powder bed formed of the powdered material on the build platform, the powdered material of the first layer is heated to a temperature between 65 percent and 70 percent of a liquidus temperature of the precipitation-hardened superalloy and, after the aforementioned pre-heating, portions of a surface of the first layer are selectively scanned by using an energy beam arrangement to melt or sinter the selectively scanned portions.

Glucose-responsive insulin conjugates

Glucose-responsive insulin conjugates that contain one or more trisaccharides are provided. Such insulin conjugates may display a pharmacokinetic (PK) and/or pharmacodynamic (PD) profile that is responsive to the systemic concentrations of a saccharide such as glucose or alpha-methylmannose, even when administered to a subject in need thereof in the absence of an exogenous multivalent saccharide-binding molecule.

SYSTEMS AND METHODS FOR DETECTING DATA EXFILTRATION

Systems and methods for detecting data exfiltration using domain name system (DNS) queries include, in various embodiments, performing operations that include parsing a DNS query to determine whether that DNS query is likely to contain hidden data that is being exfiltrated from a system or network. Statistical methods can be used to analyze the DNS query to determine a likelihood whether each of a plurality of segments of the DNS query are indicative of data exfiltration methods. If one or multiple DNS queries are deemed suspicious based on the analysis, a security action on the DNS query can be performed, including sending an alert and/or blocking the DNS query from being forwarded. 1. A system comprising:a non-transitory memory; and receiving a domain name system (DNS) query;', 'parsing the DNS query to determine a plurality of segments within the DNS query;', 'determining a likelihood that each of the plurality of segments appears in a training set of DNS queries;', 'aggregating the likelihoods of each of the plurality of segments;', 'comparing the aggregate of the likelihoods to a cutoff threshold; and', determining that the DNS query is suspicious; and', 'responsive to one or more previous DNS queries also being suspicious, performing a security action., 'in response to determining that the aggregate of the likelihoods is below the cutoff threshold], 'one or more hardware processors coupled to the non-transitory memory and configured to read instructions from the non-transitory memory to cause the system to perform operations comprising2. The system of claim 1 , wherein each of the plurality of segments comprises one or more symbols from a lowest level subdomain string in the DNS query.3. The system of claim 1 , wherein each of the plurality of segments comprises a plurality of adjacent symbols from a lowest level subdomain string in the DNS query.4. The system of claim 1 , wherein the likelihood is a probability.5. The system of claim 1 , wherein aggregating ...

Population Anomaly Detection Through Deep Gaussianization

Anomalies in a data set may be difficult to detect when individual items are not gross outliers from a population average. Disclosed is an anomaly detector that includes neural networks such as an auto-encoder and a discriminator. The auto-encoder and the discriminator may be trained on a training set that does not include anomalies. During training, an auto-encoder generates an internal representation from the training set, and reconstructs the training set from the internal representation. The training continues until data loss in the reconstructed training set is below a configurable threshold. The discriminator may be trained until the internal representation is constrained to a multivariable unit normal. Once trained, the auto-encoder and discriminator identify anomalies in the evaluation set. The identified anomalies in an evaluation set may be linked to transaction, security breach or population trends, but broadly, disclosed techniques can be used to identify anomalies in any suitable population. 1. A system , comprising:a non-transitory memory storing instructions; and providing a multivariate unit normal of a training set;', 'generating, using a neural network of an auto-encoder, an internal representation of an evaluation set, wherein the internal representation includes a plurality of elements independent from each other and generated from a plurality of elements in the evaluation set;', 'determining, using the multivariate unit normal and the internal representation of the evaluation set, a probability of an anomaly occurring in the evaluation set;', 'determining, using a neural network of a discriminator, a probability of each element in the plurality of elements in the internal representation belonging to the anomaly; and', 'determining, using the neural network of the auto-encoder and the probability of each element in the internal representation, a probability that each element in the plurality of elements in the evaluation set belongs to the ...

Systems and Methods for Human Activity Recognition Using Analog Neuromorphic Computing Hardware

Systems, methods, and devices are provided for human activity recognition. An example device includes an integrated circuit for human activity recognition. The integrated circuit includes an analog network of analog components configured to implement a trained neural network model (e.g., an autoencoder) that is trained to generate a plurality of descriptors for a plurality of predefined human activities based on a plurality of features extracted from a plurality of electrical signals from one or more sensors. The device also includes one or more digital components configured to classify human activity (e.g., using a classifier, such as K-Nearest Neighbor) as one of the plurality of predefined human activities according to the plurality of descriptors generated by the integrated circuit. In some implementations, the device further includes the one or more sensors configured to collect the plurality of electrical signals during the human activity.

Mode-1 downlink control information transmission-reception for configured sidelink scheduling in nr v2x

Various embodiments of the present disclosure may be used to determine how activation downlink control information (DCI), release DCI, and dynamic retransmission DCI are distinguished for DCI formats 3_0/3_1 for Mode-1 sidelink resource allocation. Furthermore, in case of asynchronous downlink (DL) and sidelink (SL) carriers, embodiments of the present disclosure may be used to determine how a user equipment (UE) determines transmission slots with respect to system frame number (SFN) or direct frame number (DFN) when activated with Type 1 configured scheduling.

Lossless color image compression adaptively using spatial prediction or inter-component prediction

An improved lossless image compression technique involves adaptively selecting between spatial prediction and inter-component prediction techniques depending on which allows better results for any given component of a digital image pixel.

MULTI-REFLECTION MASS SPECTROMETER WITH DECELERATION STAGE

Disclosed herein is a multi-reflection mass spectrometer comprising two ion mirrors spaced apart and opposing each other in an X direction, each mirror elongated along a drift direction Y orthogonal to the direction X, and an ion injector for injecting ions as an ion beam into the space between the ion mirrors at an inclination angle to the X direction. Along a first portion of their length in the drift direction Y the ion mirrors converge with a first degree of convergence, and along a second portion of their length in the drift direction Y the ion mirrors converge with a second degree of convergence or are parallel, the first portion of their length being closer to the ion injector than the second portion and the first degree of convergence being greater than the second degree of convergence. 1. A multi-reflection mass spectrometer comprising two ion mirrors spaced apart and opposing each other in an X direction , each mirror elongated generally along a drift direction Y , the X direction being orthogonal to the drift direction Y , and an ion injector for injecting ions as an ion beam into the space between the ion mirrors at an inclination angle to the X direction , wherein along a first portion of their length in the drift direction Y the ion mirrors converge with a first degree of convergence and along a second portion of their length in the drift direction Y the ion mirrors converge with a second degree of convergence or are parallel , the first portion of their length being closer to the ion injector than the second portion and the first degree of convergence being greater than the second degree of convergence.2. The multi-reflection mass spectrometer of wherein the first degree of convergence is such that the drift velocity of the ions in the direction Y is reduced across the first portion of length by at least 5% after the ions undergo one or more reflections in the ion mirrors in the first portion of length.3. The multi-reflection mass spectrometer of ...

Contiguity Preserving Transposition

Embodiments provided herein relate to methods and compositions for preparing an immobilized library of barcoded DNA fragments of a target nucleic acid, identifying genomic variants, determining the contiguity information, phasing information, and methylation status of the target nucleic acid.

Process for preparing methacrolein

Provided is a process for preparing methacrolein which maximizes capture of methanol. Also provided are processes for producing methacrylic acid and methyl methacrylate.

Fast provisioning of a multi-function device

A client management server predicts a desired configuration of clients deployed in an enterprise based on various signals. This prediction is a best guess for a desired functionality of the client from a predefined set of possible functionalities (e.g., wayfinding, room management, dashboard, sign-in kiosk, digital sign, and point of sale terminal). Based on this prediction, the client management server facilitates provisioning of the clients with a configuration that supports the predicted functionality. The client management server may populate configuration fields located on an administrator client. An administrator can review the populated configuration fields and confirm that the predicted configuration is correct by sending a confirmation signal back to the central server. Upon receiving confirmation from the administrator client, the central server can provision the client with the predicted configuration. Otherwise, the administrator can modify the configuration fields in order to reflect the intended functionality of the client.

SUBNET-BASED DEVICE ALLOCATION WITH GEOFENCED ATTESTATION

An IoT hub comprising one or more servers and databases is configured to automatically assign Internet of Things (IoT) enabled devices to IoT solutions based on a subnet to which the IoT devices are connected. A user interface is configured to enable a user to define subnets within the customer's network environment and assign each subnet to an IoT solution. Upon the user setting up an IoT device's network connection to a network device, such as a router, the IoT device transmits its network information to the IoT hub. The IoT hub can then automatically assign the IoT device to a specific IoT solution without further user input or predict which IoT solution to utilize for that IoT device based on known parameters. 1. A method performed by an Internet of Things (IoT) hub configured using one or more servers operatively coupled to a wide area network , comprising:receiving a connection request and network information from an IoT device;using the network information, identifying a subnet from which the IoT device is connecting, wherein the subnet provides an interface to the wide area network to enable communications between the IoT device and the IoT hub;responsive to the received connection request, selecting an IoT solution, among a plurality of different IoT solutions, with which to connect the IoT device based on the identified subnet; andconnecting the IoT device to the selected IoT solution.2. The method of claim 1 , further comprising:validating that the IoT devices are in an acceptable location as defined by a geofence;receiving location information from the IoT device;verifying the IoT device is within the established geofence using the received location information;if the location of the IoT device is inside the established geofence, then connecting the IoT device with the selected IoT solution; andif the location of the IoT device is outside the established geofence, then rejecting the connection and utilization of the determined IoT solution with the IoT ...

Method of Enhancing Fatigue Life of Grid Arrays

A method is presented that improves reliability for the mechanical electrical connection formed between a grid array device, such as a pin grid array device (PGA) or a column grid array device (CGA), and a substrate such as a printed circuit board (PCB). Between adjacent PCB pads, the method increases a spacing pattern toward the periphery of the CGA, creating a misalignment between pads and columns. As part of the method, columns align with the pads, resulting in column tilt that increases from the center to the periphery of the CGA. An advantage of the method is that the column tilt reduces the amount of contractions and expansions of columns during thermal cycling, thereby increasing the projected life of CGA. Another advantage of the method is that it reduces shear stress, further increasing the projected life of the CGA. 1. (canceled)2. An electronic assembly comprising:a printed circuit board having an array of connecting pads and a board coefficient of thermal expansion; andan electronic component having an array of connecting lands, the electronic component having a different coefficient of thermal expansion than the board coefficient of thermal expansion, an array of high melting temperature conducting posts connecting the electronic component from the array of connecting lands to respective pads of the array of connecting pads on the printed circuit board through connective material having a lower melting temperature than melting temperature of the conducting posts, angled conducting posts of the array of conducting posts having an angular tilt outwardly away from a center of the electronic component to the circuit board at 20 degrees Celsius and over a temperature range of 0 degrees Celsius to 100 degrees Celsius.3. The assembly of claim 2 , wherein the angled conducting posts include peripheral conducting posts that are peripheral with respect to the center of the electronic component.4. The assembly of claim 2 , wherein the board coefficient of ...

Method for production of methyl methacrylate by oxidative esterification using a heterogeneous catalyst

A method for preparing methyl methacrylate from methacrolein and methanol. The method comprises contacting a mixture comprising methacrolein, methanol and oxygen with a heterogeneous catalyst comprising a support and a noble metal; wherein said catalyst has an average diameter of at least 200 microns and average concentration of methacrolein is at least 15 wt %.

Architecture for implementing erasure coding

Disclosed is an improved approach to implement erasure coding, which can address multiple storage unit failures in an efficient manner. The approach can effectively address multiple failures of storage units by implementing diagonal parity sets.

A method for production of methyl methacrylate by oxidative esterification using a heterogeneous catalyst

A method for preparing methyl methacrylate from methacrolein and methanol. The method comprises contacting a mixture comprising methacrolein, methanol and oxygen with a heterogeneous catalyst comprising a support and a noble metal, wherein said catalyst has an average diameter of at least 200 microns and at least 90 wt % of the noble metal is in the outer 70% of catalyst volume, and wherein oxygen concentration at a reactor outlet is from 0.5 to 7.5 mol %.

Robotic system for performing pattern recognition-based inspection of pharmaceutical containers

A robotic inspection platform comprises a robotic arm, an imager, and a controller. The controller causes the robotic arm to retrieve, using its end effector, a container, and to manipulate the container such that the container is sequentially placed in a plurality of orientations while in view of the imager. The controller also causes the imager to capture images, with each of the images being captured while the container is in a respective one of the orientations. The controller also determines one or more attributes of the container, and/or a sample within the container, by analyzing the images using a pattern recognition model and, based on the attribute(s), determines whether the container and/or sample satisfies one or more criteria. If the container and/or sample fails to satisfy the criteria, the controller causes the robotic arm to place the container in an area (e.g., bin) reserved for rejected containers and/or samples.

System and method for creating and analyzing a low-dimensional representation of webpage sequences

Methods and systems for creating and analyzing low-dimensional representation of webpage sequences are described. Network traffic history data associated with a particular website is retrieved and a word embedding algorithm is applied to the network traffic history data to produce a low dimensional embedding. A prediction model is created based on the low-dimensional embedding. Browsing activity on the particular website is monitored. A set of sessions in the current browsing activity is flagged based on a result of applying the prediction model to the monitored browsing activity.

Systems, methods and devices for cellular synchronization references

Cellular (e.g., LTE or UMTS) and global navigation satellite system (GNSS) based technologies can provide ubiquitous and seamless synchronization solution for LTE-based vehicle to everything (V2X) or Proximity Services synchronization (ProSe) services. For example, by using joint GNSS timing references and LTE cellular network timing references for V2X or ProSe system synchronization benefits of using GNSS technologies to improve synchronization procedure for LTE based V2X or ProSe services can be enabled, including: (1) accurate and stable timing, (2) availability of a global and stable timing reference and (3) ability to propagate GNSS timing by user equipment having sufficient GNSS signal quality.

Ion Guide

An ion guide for mass spectrometry comprising an electrode arrangement of at least two electrodes, at least one of which is an RF electrode, arranged adjacent to each other but spaced apart on a planar surface of a dielectric material and arranged at a distance from an ion flow path, wherein a portion of the dielectric surface is exposed between an adjacent pair of the spaced apart electrodes and wherein at least one electrode of said adjacent pair of electrodes is arranged to overhang the exposed portion of surface between them such that there is no direct line of sight from the ion flow path to the exposed portion of dielectric surface. The device enables RF guiding of ions accompanied by much reduced charging-up of dielectric surfaces and reduced amount of collisions of neutral species with electrodes. 1. An ion guide for mass spectrometry comprising an electrode arrangement of at least two electrodes , at least one of which is an RF electrode , arranged adjacent to each other but spaced apart on a planar surface of a dielectric material , wherein the arrangement has been produced by separately providing the dielectric material and arranging the electrodes on it in a subsequent step , and wherein the electrodes are arranged at a distance from an ion flow path , wherein a portion of the dielectric surface is exposed between an adjacent pair of the spaced apart electrodes and wherein at least one electrode of said adjacent pair of electrodes is arranged to overhang the exposed portion of surface between them such that there is no direct line of sight from the ion flow path to the exposed portion of dielectric surface.2. The ion guide according to claim 1 , wherein the dielectric material is glass claim 1 , ceramic or printed circuit board.3. The ion guide according to claim 1 , wherein the ion guide is a multipole.4. The ion guide according to wherein ion-facing surfaces of said adjacent pair of electrodes are at different distances from the surface of the ...

ION EJECTION FROM A QUADRUPOLE ION TRAP

A method of ejecting ions to be analyzed from a quadrupole ion trap in which a trapping field is created by one or more RF voltages applied to one or more electrodes of the trap, the method comprising the steps of cooling the ions to be analyzed within the quadrupole ion trap until the ions are thermalized, reducing the amplitude of one or more RF voltages applied to the quadrupole ion trap and applying the reduced amplitude RF voltages for one half cycle after the one or more RF voltages have reached a zero crossing point, turning off the RF voltages applied to the quadrupole ion trap, and ejecting the ions to be analyzed from the quadrupole ion trap. 1. An ion ejector system for a mass analyzer comprising a quadrupole ion trap for containing a buffer gas; a RF power supply with one or more outputs electrically connected to one or more electrodes of the quadrupole ion trap; an ejection power supply with one or more outputs electrically connected to one or more electrodes of the quadrupole ion trap; and a controller electrically connected to the RF power supply and the ejection power supply , the controller arranged to:(a) control the RF power supply to supply one or more RF voltages at a first amplitude to one or more electrodes of the ion trap for a first period of time, wherein the first period of time is sufficient for ions within the quadrupole ion trap to become thermalized due to collisions with the buffer gas;(b) control the RF power supply after the first period of time to supply one or more RF voltages of a second amplitude to one or more electrodes of the quadrupole ion trap for substantially one half cycle from where the one or more RF voltages have reached a zero crossing point, the second amplitude being smaller than the first amplitude; and(c) control the RF power supply to turn off the RF voltages applied to the quadrupole ion trap after the one half cycle; the controller being arranged to perform (a) to (c) in that order.2. The ion ejector system of ...

FRAUD PREDICTION BASED ON PARTIAL USAGE DATA

A system for predicting that a user session will be fraudulent. The system can analyze an incomplete session and determine the likelihood that the session is fraudulent or not by generating completed sessions based on the incomplete session. 1. A system , comprising:a non-transitory memory storing instructions; andone or more hardware processors coupled to the non-transitory memory and configured to execute the instructions from the non-transitory memory to cause the system to perform operations comprising:collecting usage data during an active session corresponding to an in-progress incomplete task of a user;generating computer generated usage data that combines with the usage data to create a complete task that is partially computer generated;determining a probability that a task by the user from the in-progress incomplete task will be fraudulent based at least in part on the complete task that is partially computer generated; andimplementing an additional security measure based on the probability being over a threshold value.2. The system of claim 1 , wherein the operation generating computer generated usage data comprises formatting the collected usage data for input to a variational autoencoder (VAE) claim 1 , selecting a historic usage data for a completed task from a database and inputting the formatted usage data and the historic usage data for the completed task into the VAE claim 1 , the VAE configured to generate the complete task that is partially computer generated.3. The system of claim 2 , wherein the VAE comprises a decoder that is a long short term memory neural network configured to receive formatted usage data.4. The system of claim 3 , wherein the decoder was trained in a generative adversarial network (GAN) having a discriminator configured to discriminate between outputs from the decoder and historic usage data for completed tasks from the database.5. The system of claim 1 , wherein determining the probability comprises classifying the complete ...

EXTENSIBLE DEVICE IDENTITY ATTESTATION

Provisioning a requesting device is provided using extended identity attestation for the requesting device. A provisioning request is received at a device provisioning system. The provisioning request includes a registration identifier provided by the requesting device. A plurality of extended attestation components is accessed in an enrollment datastore of the device provisioning system. Each extended attestation component identifies an external computing system. One of the extended attestation components in the enrollment datastore is selected based on the received registration identifier. Execution of the device attestation is initiated at the external computing system identified by the selected extended attestation component to yield an attestation result. Satisfaction of a validity condition by the attestation result is detected. The requesting device is provisioned from the device provisioning system, responsive to detection that the attestation result satisfies the validity condition. 1. A method of provisioning a requesting device by obtaining extended identity attestation for the requesting device , the method comprising:receiving a provisioning request at a device provisioning system, the provisioning request including a registration identifier provided by the requesting device;accessing a plurality of extended attestation components in an enrollment datastore of the device provisioning system, each extended attestation component identifying an external computing system;selecting one of the extended attestation components of the enrollment datastore based on the registration identifier;initiating execution of the extended identity attestation at the external computing system identified by the selected extended attestation component to yield an attestation result; andprovisioning the requesting device from the device provisioning system, responsive to detection that the attestation result satisfies a validity condition.2. The method of wherein the ...

METHOD OF PRODUCING SPHERICAL BORON NITRIDE FINE PARTICLES

A method of producing a spherical boron nitride fine particle includes reacting ammonia with an alkoxide borate at an ammonia/alkoxide borate molar ratio of 1 to 10 in an inert gas stream at 750° C. or higher within 30 seconds, then applying heat treatment to a reaction product in an atmosphere of ammonia gas or a mixed gas of ammonia gas and an inert gas at 1,000 to 1,600° C. for at least 1 hour, and further firing the reaction product in an inert gas atmosphere at 1,800 to 2,200° C. for at least 0.5 hour. 1. A method of producing a spherical boron nitride fine particle, characterized by reacting ammonia with an alkoxide borate at an ammonia/alkoxide borate molar ratio of 1 to 10 in an inert gas stream at 750° C. or higher within 30 seconds, then applying heat treatment to a reaction product in an atmosphere of ammonia gas or a mixed gas of ammonia gas and an inert gas at 1,000 to 1,600° C. for at least 1 hour, and further firing the reaction product in an inert gas atmosphere at 1,800 to 2,200° C. for at least 0.5 hour. This is a divisional application Ser. No. 15/117,853 filed Aug. 10, 2016, which is a National Phase of International Application No. PCT/JP2015/053489 filed Feb. 9, 2015, and claims priority from Japanese Patent Application No. 2014-024009 filed Feb. 12, 2014, the disclosure of which is hereby incorporated by reference herein in its entirety.The present invention relates to a spherical boron nitride fine particle well suited for use as a highly thermoconductive filler or the like, and a production method thereof.Hexagonal boron nitride (hereinafter called “boron nitride”), because of having lubrication capability, high thermal conductivity and insulation capability, is now widely used as releasing agents for solid lubricants, molten glasses and aluminum or the like as well as fillers for thermal radiation materials.To be compatible with higher performances of recent computers and electronic hardware in particular, measures against thermal radiation ...

Bio-electric nose

An animal-based chemical detectors that can be customized to detect a wide variety of chemicals under real-world conditions. Methods and systems for brain/machine interface devices using electrodes to read odor-signatures from the patterns of activated glomeruli, for example in the rodent olfactory bulb.

AUTOMATIC INJECTION DEVICE WITH A DAMPENING ELEMENT

An automatic injection device including a generally cylindrical syringe body having an opening, an outlet and an inner cylindrical surface adapted to contain an injectable liquid to be injected at an injection site via the outlet; a piston disposed in the cylindrical syringe body; a driving assembly, including an elongate plunger element having a forward end adapted to be axially inserted into the generally cylindrical syringe body and an at least partial forward sealing element mounted onto the elongate plunger element adjacent the forward end for creating an at least temporary slidable seal between the elongate plunger element and the inner cylindrical surface, whereby axial insertion of the elongate plunger element and the forward sealing element into the generally cylindrical syringe body creates friction between the forward sealing element and the inner cylindrical surface and also creates an at least temporary air spring between the forward sealing element and the piston, wherein the friction and the air spring dampen motion of the elongate plunger element. 1. A medicament module , comprising:a module housing at least partially surrounding a needle shield and arranged along a mutual longitudinal axis therewith;an RNS remover assembly, attached to said needle shield and configured to be detachable from said needle shield but not to be subsequently re-attachable thereto.2. A medicament module according to claim 1 , and wherein said module housing has a forward end and a rearward end and at least one finger disposed between said forward end and said rearward end and wherein said finger has at least one side protrusion.3. A medicament module according to claim 2 , and wherein said needle shield has at least one mounting arm formed with a recess claim 2 , said needle shield has a forward circumferential rim.4. A medicament module according to claim 3 , and wherein said at least one mounting arm is also formed with at least one slot claim 3 , arranged rearwardly of ...

Method of preparation the smoking composition without tobacco for the hookah

The invention relates to the tobacco substitutes, in particular to smoking compositions without tobacco and is intended mainly for smoking with the hookah use. In the method of preparation the smoking composition without tobacco for the hookah which comprises the preliminary preparation of the main organic material, at least one type of fruits is used as the main organic filling material and the mix of propyleneglycol and food glycerin. The method of preparation the smoking composition without tobacco for the hookah allows to reduce the burning rate and the consumption for one filling. This method improves the quality of the smoking composition.

MULTI-REFLECTION MASS SPECTROMETER

A multi-reflection mass spectrometer is provided comprising two ion-optical mirrors, each mirror elongated generally along a drift direction (Y), each mirror opposing the other in an X direction, the X direction being orthogonal to Y, characterized in that the mirrors are not a constant distance from each other in the X direction along at least a portion of their lengths in the drift direction. In use, ions are reflected from one opposing mirror to the other a plurality of times while drifting along the drift direction so as to follow a generally zigzag path within the mass spectrometer. The motion of ions along the drift direction is opposed by an electric field resulting from the non-constant distance of the mirrors from each other along at least a portion of their lengths in the drift direction that causes the ions to reverse their direction. 1. A multi-reflection mass spectrometer comprising two ion-optical mirrors , each mirror elongated generally along a drift direction (Y) , each mirror opposing the other in an X direction and having a space therebetween , the X direction being orthogonal to Y , and further comprising one or more compensation electrodes , each electrode being elongated in the Y direction along a substantial portion of the drift length , and being located either side of the space extending between the opposing mirrors , the spectrometer further comprising an ion injector located at one end of the ion-optical mirrors in the drift direction arranged so that in use it injects ions such that they oscillate between the opposing mirrors whilst proceeding along a drift length in the Y direction; the compensation electrodes being , in use , electrically biased such that the total time of flight of ions is substantially independent of the drift length traveled.2. The multi-reflection mass spectrometer of in which the period of ion oscillation between the mirrors is not substantially constant along the whole of the drift length.3. The multi-reflection ...

SYSTEM AND METHOD FOR MALWARE DETECTION

Aspects of the present disclosure involve a system and method for malware detection. The system and method introduce a probabilistic model that can observe user transaction data over a predetermined window of time. Then, using posterior probability, the system can determine whether multiple users where present during the window observed. 1. A system comprising:a non-transitory memory storing instructions; and receiving a first request to access an account associated with a user from a first device;', 'receiving a second request to access the account associated with the user from a second device;', 'in response to the first and second request, initiating a malware detection check, wherein in the malware detection check includes generating a user transaction model for the user associated with the first device and a second user transaction model for the user associated with the second device; and', 'determining that the second user is an unauthorized user of the account, wherein the determining is based in part on the malware detection check., 'a processor configured to execute instructions to cause the system to2. The system of claim 1 , wherein the malware detection check further includes retrieving an activity log of the first user for the first device claim 1 , and comparing the activity log to the first and second user transactional models generated.3. The system of claim 2 , wherein the activity log is a fragment of a total activity log claim 2 , and wherein the fragment of the total activity log is determined using a windowing scheme.4. The system of claim 3 , wherein the windowing scheme includes determining a window length and a window for selecting the fragment of the total activity log.5. The system of claim 1 , wherein a probability distribution for multiuser access is determined.6. The system of claim 1 , wherein determining the second user is the unauthorized user is based on a comparison and inference of a probability that two users are accessing the ...

System and Method for Creating and Analyzing A Low-Dimension Representation of Webpage Sequence

Methods and systems for creating and analyzing low-dimensional representation of webpage sequences are described. Network traffic history data associated with a particular website is retrieved and a word embedding algorithm is applied to the network traffic history data to produce a low dimensional embedding. A prediction model is created based on the low-dimensional embedding. Browsing activity on the particular website is monitored. A set of sessions in the current browsing activity is flagged based on a result of applying the prediction model to the monitored browsing activity. 120-. (canceled)21. A system , comprising:a non-transitory memory; and applying a word embedding algorithm to network traffic history data corresponding to browsing behavior of a plurality of users visiting a plurality of webpages on a merchant website, the applying the word embedding algorithm causes the plurality of webpages to be represented as words and the browsing behavior of the plurality of users visiting the plurality of websites to be represented as vectors;', 'generating, based on the words and vectors, a low-dimensional representation of the browsing behavior that associates an abandoned transaction with a type of user browsing behavior;', 'predicting, based on the low-dimensional representation of the browsing behavior, a cart abandonment with respect to the website by identifying a group of vectors corresponding to abandoned transaction; and', 'in response to predicting the cart abandonment, altering a next instance of a webpage on the merchant website., 'one or more hardware processors coupled to the non-transitory memory and configured to read instructions from the non-transitory memory to cause the system to perform operations comprising22. The system of claim 21 , wherein the next instance of the webpage on the merchant website is altered to promote a different navigation pattern from a current navigation pattern.23. The system of claim 22 , wherein the different ...

AUTOMATIC INJECTION DEVICE WITH A DAMPENING ELEMENT

An automatic injection device including a generally cylindrical syringe body having an opening, an outlet and an inner cylindrical surface adapted to contain an injectable liquid to be injected at an injection site via the outlet; a piston disposed in the cylindrical syringe body; a driving assembly, including an elongate plunger element having a forward end adapted to be axially inserted into the generally cylindrical syringe body and an at least partial forward sealing element mounted onto the elongate plunger element adjacent the forward end for creating an at least temporary slidable seal between the elongate plunger element and the inner cylindrical surface, whereby axial insertion of the elongate plunger element and the forward sealing element into the generally cylindrical syringe body creates friction between the forward sealing element and the inner cylindrical surface and also creates an at least temporary air spring between the forward sealing element and the piston, wherein the friction and the air spring dampen motion of the elongate plunger element. 1. An automatic injection device comprising:a generally cylindrical syringe body having an opening, an outlet and an inner cylindrical surface adapted to contain an injectable liquid to be injected at an injection site via said outlet;a piston disposed in said cylindrical syringe body;a driving assembly, including an elongate plunger element having a forward end adapted to be axially inserted into said generally cylindrical syringe body and an at least partial forward sealing element mounted onto said elongate plunger element adjacent said forward end for creating an at least temporary slidable seal between said elongate plunger element and said inner cylindrical surface,whereby axial insertion of said elongate plunger element and said forward sealing element into said generally cylindrical syringe body creates friction between said forward sealing element and said inner cylindrical surface and also creates ...

Network Based CRS Mitigation

An apparatus of a user equipment (UE), comprises one or more baseband processors to receive one or more subframes from a cell of a network, and to detect a Cell Specific Reference Signal (CRS) transmission pattern in the one or more subframes to determine whether CRS mitigation is used by the cell, wherein the one or more baseband processors are to adjust processing of the one or more subframes when CRS mitigation is used. The apparatus further includes a memory to store the one or more subframes.

Method and apparatus for visualizing risk levels associated with aerial vehicle flights

An approach is provided for visualizing risk levels associated with aerial vehicle flights. The approach, for example, involves determining a flight path for an aerial vehicle. The approach also involves calculating at least one risk area along the flight path based on risk-related data associated with the flight path (e.g., data on population density, electromagnetic fields, absence of location signals such as Global Positioning System (GPS) signals, weather, network coverage, aviation related data, etc.). The approach further involves generating a representation of the at least one risk area as a virtual obstacle object and rendering the virtual obstacle object in a user interface of a device in relation to the flight path.

Method of Producing a Mass Spectrum

A method of producing a mass spectrum from a time-varying transient signal detected in a mass spectrometer, the method comprising: performing a Fourier transform of the transient signal to produce a first set of complex amplitudes wherein each of the complex amplitudes corresponds to a respective frequency of a first set of frequencies; generating a second set of complex amplitudes, wherein each of the complex amplitudes corresponds to a respective frequency of a second set of frequencies with a minimum spacing less than the inverse of the duration of the transient signal; optimizing the second set of complex amplitudes to produce an improved second set; generating a mass spectrum from at least some of the improved second set of complex amplitudes; wherein optimizing the second set of complex amplitudes to produce an improved second set of complex amplitudes is based on an objective function subject to some phase constraints. 1. A system for producing a mass spectrum from a time-varying transient signal , the system comprising: an ion source for producing ions from a sample; and', 'a Fourier transform mass analyzer configured to trap the ions within a trapping field and generate a transient signal from the oscillation of the ions within the trapping field;, 'a mass spectrometer including receive the transient signal from the mass spectrometer;', 'perform a Fourier transform of the transient signal to produce a first set of complex amplitudes wherein each of the complex amplitudes corresponds to a respective frequency of a first set of frequencies;', 'generate a second set of complex amplitudes, wherein each of the complex amplitudes corresponds to a respective frequency of a second set of frequencies, wherein the minimum spacing of the second set of frequencies is less than the inverse of the duration of the transient signal;', 'optimize the second set of complex amplitudes to produce an improved second set of complex amplitudes;', 'generate a mass spectrum from at ...

Method of preparing tobacco-free smoking composition for hookah

The invention relates to tobacco substitutes, and specifically to tobacco-free smoking compositions, and is principally intended for smoking using a hookah. In the method of preparing a tobacco-free smoking composition for a hookah, including the preliminary preparation of a main organic material, the main organic filler being comprised of at least one type of fruit, and of a binding agent consisting of a mixture of propylene glycol and food-grade glycerin in a ratio of (1:4)-(4:1), wherein the preliminary preparation of the main organic filler material is carried out by means of freeze-drying, in the process of which, the fruit is crushed to a fraction-size of 3-12 mm, frozen in liquid nitrogen at a temperature of (−40) to (−60) degrees Celsius, and kept in a vacuum for 30-40 minutes, thus forming the filler material, which has a residual moisture content of 1-6% and which is impregnated with binding agent using the following ratio of compositional components by mass percent: main organic filler material: 10-55; binding agent: the remainder. Technical result: the method of preparing a tobacco-free smoking composition for a hookah allows for reducing the rate of combustion, decreasing the rate of use per filling, and improving the quality thereof

COMBINED REGISTRATION AND TELEMETRY REPORTING

Examples are disclosed that relate to using a multiplexed transmission to register a telemetry device with a telemetry system and report telemetry data to the telemetry system on behalf of a telemetry device. One disclosed example provides a method comprising receiving a multiplexed transmission from a telemetry device, the multiplexed transmission comprising a registration message and telemetry data, demultiplexing the multiplexed transmission to obtain the registration message and the telemetry data, registering the telemetry device with a telemetry system based upon the registration message, sending the telemetry data to the telemetry system, and sending a registration response to the telemetry device, the registration response confirming registration of the telemetry device with the telemetry system. 1. A method , comprising:receiving a multiplexed transmission from a telemetry device, the multiplexed transmission comprising a registration message and telemetry data;demultiplexing the multiplexed transmission to obtain the registration message and the telemetry data;registering the telemetry device with a telemetry system based upon the registration message;sending the telemetry data to the telemetry system; andsending a registration response to the telemetry device, the registration response confirming registration of the telemetry device with the telemetry system.2. The method of claim 1 , wherein sending the registration response to the telemetry device comprises sending information usable by the telemetry device to connect to the telemetry system.3. The method of claim 1 , wherein registering the telemetry device with the telemetry system comprises registering the telemetry device with a cloud-based service associated with a user of the telemetry device.4. The method of claim 1 , wherein the telemetry data comprises location data claim 1 , the method further comprisingcomparing the location data received to a predefined physical boundary for the telemetry ...

Three-dimensional elastic frequency-domain iterative solver for full waveform inversion

Certain implementations of a three-dimensional elastic frequency domain iterative solver for full waveform inversion can be implemented as a method in which frequency domain numerical simulation of elastic waves is per formed in three-dimensional (3D) media.

ION INJECTION FROM A QUADRUPOLE ION TRAP

A method of ejecting ions to be analysed from a quadrupole ion trap in which a trapping field is created by one or more RF voltages applied to one or more electrodes of the trap, the method comprising the steps of cooling the ions to be analysed within the quadrupole ion trap until the ions are thermalized, reducing the amplitude of one or more RF voltages applied to the quadrupole ion trap and applying the reduced amplitude RF voltages for one half cycle after the one or more RF voltages have reached a zero crossing point, turning off the RF voltages applied to the quadrupole ion trap, and ejecting the ions to be analysed from the quadrupole ion trap. 1. A method of ejecting ions to be analysed from a quadrupole ion trap in which a trapping field is created by one or more RF voltages applied to one or more electrodes of the trap , the method comprising the following steps:(a) cooling the ions to be analysed within the quadrupole ion trap until the ions are thermalized;(b) reducing the amplitude of one or more RF voltages applied to the quadrupole ion trap and applying the one or more reduced amplitude RF voltages for substantially one half cycle from where the one or more RF voltages have reached a zero crossing point;(c) turning off the one or more RF voltages applied to the quadrupole ion trap after the one half cycle; steps (a) to (c) being performed in that order; and(d) ejecting the ions to be analysed from the quadrupole ion trap concurrently with or after step (c).2. The method of wherein the quadrupole ion trap is a linear trap comprising four electrodes extended generally parallel to an axis claim 1 , the four electrodes comprising two opposing pairs of electrodes; a first opposing pair of electrodes having a first RF voltage applied to them and a second opposing pair of electrodes having a second RF voltage applied to them claim 1 , the first and second RF voltages being of opposite polarities.3. The method of wherein the quadrupole ion trap is a 3D trap ...

ION INJECTION TO AN ELECTROSTATIC TRAP

Ions are injected into an orbital electrostatic trap. An ejection potential is applied to an ion storage device, to cause ions stored in the ion storage device to be ejected towards the orbital electrostatic trap. Synchronous injection potentials are applied to a central electrode of the orbital electrostatic trap and a deflector electrode associated with the orbital electrostatic trap, to cause the ions ejected from the ion storage device to be captured by the electrostatic trap such that they orbit the central electrode. Application of the ejection potential and application of the synchronous injection potentials are each started at respective different times, the difference in times being selected based on desired values of mass-to-charge ratios of ions to be captured by the orbital electrostatic trap. 1. A method of injecting ions into an orbital electrostatic trap , comprising:applying an ejection potential to an ion storage device, to cause ions stored in the ion storage device to be ejected towards the orbital electrostatic trap; andapplying synchronous injection potentials to a central electrode of the orbital electrostatic trap and a deflector electrode associated with the orbital electrostatic trap, to cause the ions ejected from the ion storage device to be captured by the electrostatic trap such that they orbit the central electrode;wherein the steps of applying the ejection potential and applying the synchronous injection potentials are each started at respective different times, the difference in times being selected based on desired values of mass-to-charge ratios of ions to be captured by the orbital electrostatic trap.2. The method of claim 1 , wherein one or both of a magnitude and a direction of the difference between the time at which the step of applying the ejection potential is started and the time at which the step of applying the synchronous injection potentials is started is or are selected based on the desired values of mass-to-charge ...

Isothiocyanato-tolanes

as defined in claim 1, and high-frequency components comprising these media, especially microwave components for high-frequency devices, such as devices for shifting the phase of microwaves, tunable filters, tunable metamaterial structures, and electronic beam steering antennas, e.g. phased array antennas.

Photo realistic rendering of smile image after treatment

A method may include: receiving facial image of the patient that depicts the patient's teeth; receiving a 3D model of the patient's teeth; determining color palette of the depiction of the patient's teeth; coding 3D model of the patient's teeth based on attributes of the 3D model; providing the 3D model, the color palette, and the coded 3D model to a neural network; processing the 3D model, the color palette, and the coded 3D model by the neural network to generate a processed image of the patient's teeth; simulating specular highlights on the processed image of the patient's teeth; and inserting the processed image of the patient's teeth into a mouth opening of the facial image.

REUSABLE AUTOMATIC INJECTION DEVICE

A user-powered medicament injector including a reusable, user-powered automatic injection assembly including a user energizable medicament injection subassembly and a medicament module removably insertable into the reusable, user-powered automatic injection assembly and including a module housing adapted to receive a syringe having a barrel, a needle engaged to said barrel, and a removable needle cap covering the needle; a needle shield configured to be moveable with respect to the module housing and a needle cap remover associated with the needle shield. The medicament module is configured for energizing the user energizable medicament injection subassembly by insertion of the medicament module into the reusable, user powered automatic injection assembly. 1. A user-powered medicament injector comprising:a reusable, user-powered automatic injection assembly including a user energizable medicament injection subassembly; anda medicament module removably insertable into said reusable, user-powered automatic injection assembly and comprising:a module housing adapted to receive a syringe having a barrel, a needle engaged to said barrel, and a removeable needle cap covering said needle;a needle shield configured to be moveable with respect to said module housing; anda needle cap remover associated with said needle shield;and wherein said medicament module is configured for energizing said user energizable medicament injection subassembly by insertion of said medicament module into said reusable, user powered automatic injection assembly.2. A user-powered medicament injector according to and wherein said user energizable medicament injection assembly comprises at least one mechanical energy storage element.3. A user-powered medicament injector according to and wherein said at least one mechanical energy storage element comprises at least one resilient element and wherein said insertion of said medicament module into said reusable claim 2 , user powered automatic injection ...

MASS SPECTROMETER AND METHOD FOR TIME-OF-FLIGHT MASS SPECTROMETRY

A mass spectrometer comprising: a pulsed ion source for generating pulses of ions having a range of masses; a time-of-flight mass analyzer for receiving and mass analyzing the pulses of ions from the ion source; and an energy controlling electrode assembly located between the pulsed ion source and the time-of-flight mass analyzer configured to receive the pulses of ions from the pulsed ion source and apply a time-dependent potential to the ions thereby to control the energy of the ions depending on their m/z before they reach the time-of-flight mass analyzer. Mass dependent differences in average energy of ions can be reduced for injection into a time-of-flight mass analyzer, which can improve ion transmission and/or instrument resolving power. 1. A mass spectrometer comprising:a pulsed ion source for generating pulses of ions having a range of masses;a time-of-flight mass analyzer for receiving and mass analyzing the pulses of ions generated by the ion source; andan energy controlling electrode assembly, located between the pulsed ion source and the time-of-flight mass analyzer, positioned to receive the pulses of ions from the pulsed ion source and configured to apply a time-dependent potential to the ions, wherein the application of the time-dependent potential changes the energies of at least a portion of the ions to reduce the variation of ion energy with mass-to-charge ratio (m/z).2. The mass spectrometer of claim 1 , wherein the time-dependent potential is synchronised to the arrival times of ions whose energy is to be changed.3. The mass spectrometer of claim 2 , wherein the ions whose energy is to be changed are ions at the low mass end of the range of masses.4. The mass spectrometer of claim 3 , wherein the time-dependent potential lifts the energy of the ions at the low mass end of the range of masses.5. The mass spectrometer of claim 1 , wherein the pulsed ion source comprises an RF ion trap.6. The mass spectrometer of claim 1 , wherein the time-of- ...

MASS SPECTROMETER AND METHOD FOR TIME-OF-FLIGHT MASS SPECTROMETRY

A mass spectrometer comprising: a pulsed ion source for generating pulses of ions having a range of masses; a time-of-flight mass analyzer for receiving and mass analyzing the pulses of ions from the ion source; and an energy controlling electrode assembly located between the pulsed ion source and the time-of-flight mass analyzer configured to receive the pulses of ions from the pulsed ion source and apply a time-dependent potential to the ions thereby to control the energy of the ions depending on their m/z before they reach the time-of-flight mass analyzer. Mass dependent differences in average energy of ions can be reduced for injection into a time-of-flight mass analyzer, which can improve ion transmission and/or instrument resolving power. 1. A mass spectrometer comprising:a pulsed ion source for generating pulses of ions having a range of masses;a time-of-flight mass analyzer for receiving and mass analyzing the pulses of ions from the ion source; andan energy controlling electrode assembly located between the pulsed ion source and the time-of-flight mass analyzer configured to receive the pulses of ions from the pulsed ion source and apply a time-dependent potential to the ions thereby to control the energy of the ions depending on their m/z before they reach the time-of-flight mass analyzer.2. The mass spectrometer of claim 1 , wherein the time-dependent potential is synchronised to the arrival times of ions whose energy is to be changed.3. The mass spectrometer of claim 2 , wherein the ions whose energy is to be changed are ions at the low mass end of the range of masses.4. The mass spectrometer of claim 3 , wherein the time-dependent potential lifts the energy of the ions at the low mass end of the range of masses.5. The mass spectrometer of claim 1 , wherein the pulsed ion source comprises an RF ion trap.6. The mass spectrometer of claim 1 , wherein the time-of-flight mass analyzer is a multi-reflection time-of-flight mass analyzer having a mass resolving ...

Ion front tilt correction for Time of Flight (TOF) mass spectrometer

Correction of an angle of tilt of an ion beam front in a Time of Flight (TOF) mass spectrometer is described. In one aspect, an ion beam front tilt corrector can include an electrode that, when applied with a voltage, defines an equipotential channel of particular dimensions to allow for ions in different transverse positions along a transverse axis of the equipotential channel to have different traversal times. 1. A time of flight (TOF) ion beam front tilt corrector , comprising:{'sub': TC', 'TC', 'TC', 'TC', 'TC', 'TC', 'TC', 'TC, 'at least one electrode which, when supplied with a voltage, defines a substantially equipotential channel, the channel extending in a longitudinal direction Z, the channel further extending a first, longer distance along a first transverse axis Xdefined perpendicular to the longitudinal direction Z, and a second, shorter distance along a second transverse axis Y, perpendicular with both the first axis Xand the longitudinal axis Z, wherein the ratio of the first, longer distance along the first axis Xto the second, shorter distance along a second axis Yis at least 2;'}{'sub': TC', 'TC', 'TC', 'TC', 'TC, 'wherein the length of the channel in the longitudinal direction Zvaries in accordance with the transverse position in the direction Xorthogonal to the longitudinal direction Zof the channel, so that ions at a first transverse position Xin the ion beam spend a different amount of time traversing the channel of the at least one electrode, to ions in a second, different transverse position Xof the ion beam.'}2. The TOF ion beam front tilt corrector of claim 1 , wherein the ratio of the first claim 1 , longer distance along the first transverse axis Xto the second claim 1 , shorter distance along the second transverse axis Yis between 2 and 10.3. The TOF ion beam front tilt corrector of claim 2 , wherein the ratio of the first claim 2 , longer distance along the first transverse axis Xto the second claim 2 , shorter distance along the second ...

Ion Trap with Elongated Electrodes

An ion trap 1 comprises one ejection electrode 2 for ion trapping having an opening 4, through which ions in the ion trap 1 can be ejected in an ejection direction E and further electrodes 3 for ion trapping, wherein the ejection electrode 2 and the further electrodes 3 are elongated in a longitudinal direction L. The angle α between the longitudinal direction L and the ejection direction E is nearly The ion trap 1 comprises a primary winding 5 connected to an RF power supply 6, a secondary winding 7 coupling with the primary winding 5 for transforming the RF voltage of the RF power supply 6 supplying the transformed RF signals to the ejection electrode 2 and secondary windings 7′ coupling with the primary winding 5 for transforming the RF voltage of the RF power supply 6 supplying the transformed RF signals to the further electrodes 3. The ion trap 1 comprises a first DC supply 8, a second DC supply 9 and a controller 50, which is applying in a time period a first DC voltage provided by first DC supply 8 via the secondary winding 7 to the ejection electrode 2 to pull ions in the ion trap to the opening 4 of the ejection electrode 2 and a second DC voltage provided by the second DC supply 9 via the secondary windings 7′ to the at least % of the further electrodes 3 to push ions in the ion trap to the opening 4 of the ejection electrode 2. 23. The ion trap according to claim 1 , wherein the ion trap is comprising further electrodes.35. The ion trap according to claim 1 , wherein the ion trap is comprising further electrodes.47. The ion trap according to claim 1 , wherein the ion trap is comprising further electrodes.5. The ion trap according to claim 1 , wherein the ion trap is a curved ion trap.6. The ion trap according to claim 1 , wherein the angle α between the longitudinal direction L and the ejection direction E deviates from 90° not more than 7° claim 1 , preferably not more than 3°.7. The ion trap according to claim 1 , wherein the controller is applying in ...

System and Method for Malware Detection

Aspects of the present disclosure involve a system and method for malware detection. The system and method introduce a probabilistic model that can observe user transaction data over a predetermined window of time. Then, using posterior probability, the system can determine whether multiple users where present during the window observed. 1. A system comprising:a non-transitory memory; and in response to a determination that a malware detection check is being performed, retrieving an electronic user transaction log relating to an account, the electronic user transaction log including first transactions conducted by a first user online and second transactions conducted by a second user online;', 'retrieving a first probabilistic structure defined by a first set of parameters and a second probabilistic structure that is different from the first probabilistic structure and defined by a second set of parameters;', 'generating, using a first process that estimates the first set of parameters for the first probabilistic structure to approximate a first plurality of amounts of the first transactions relating to the first user and a first plurality of times when the first transactions occur, a first user transaction model for the first user;', 'generating, using a second process that estimates the second set of parameters for the second probabilistic structure to approximate a second plurality of amounts of the second transactions relating to the second user and a second plurality of times when the second transactions occur, a second user transaction model for the second user;', 'determining a window length and a window of the electronic user transaction log for observing user transaction data relating to the account, the window including a fragmentation of the electronic user transaction log within a time duration of the determined window length;', 'computing, using the first user transaction model and the second user transaction model, a posterior probability indicating a ...

Wavelength selective reconfigurable optical cross-connect

An optical coupling device including: at least a first input port for delivering an optical input signal beam that includes a plurality of wavelength channels; at least a first optical output port for receiving an optical output signal beam; a wavelength dispersion element for spatially separating the plurality of wavelength channels in the optical input signal beam to form a plurality of spatially separated wavelength channel beams; an optical coupling device for independently modifying the phase of each of the spatially separated wavelength channel beams such that, for at least one wavelength channel beam, a selected fraction of the light is coupled to the first output port and a fraction of the light is coupled away from the first output port.

CMP compositions and methods for selective removal of silicon nitride

The present invention provides chemical mechanical polishing compositions and methods for polishing a substrate comprising silicon dioxide and silicon nitride, which provide selective removal of SiN relative to silicon oxide (e.g., PETEOS) on patterned wafers. In one embodiment, a CMP method comprises abrading a surface of a substrate comprising SiN and silicon oxide with a CMP composition to remove at least some SiN therefrom. The CMP composition comprises, consists essentially of, or consists of a particulate abrasive (e.g., ceria) suspended in an aqueous carrier and containing a cationic polymer bearing pendant quaternized nitrogen-heteroaromatic moieties, wherein the composition has a pH of greater than about 3.

Display apparatuses, systems and methods including curved waveguides

Apparatuses and systems including curved optical waveguides, and methods for use include an output-grating of a curved waveguide that includes a spatially modulated grating period configured to cause, for each beam of light corresponding to an image coupled into a bulk-substrate of the curved waveguide by an input-grating, corresponding rays of light output from different locations of the output-grating to be substantially collimated. Adaptive optics of a display engine compensate for aberrations that vary over a field-of-view associated with light corresponding to the image out-coupled by the output-grating. Further, a curved portion of the curved waveguide is designed to keep internally reflected light below a critical angle to prevent inadvertent out-coupling thereof. Further, curved surfaces of the curved waveguide can include polynomial surfaces to compensate for lateral color errors and distortion.

Eye-tracking system positioning diffractive couplers on waveguide

An eye-tracking system includes an at least partially transparent visible light waveguide having a visible light display region configured to emit visible light to an eye of a user. A light source is configured to emit at least infrared (IR) light that travels along an IR light path to the eye of the user. A microelectromechanical system (MEMS) projector positioned in the IR light path directs the IR light. At least one diffractive input coupler on an input end of the IR light path downstream of the MEMS projector diffracts at least a portion of the IR light. At least one diffractive output coupler positioned in the IR light path downstream of the diffractive input coupler receives the IR light and directs the IR light toward the eye. At least one sensor is configured to receive the IR light after being reflected by the eye.

Pupil-expanding display device

Examples are disclosed that relate to a display device. One example provides a display device comprising a projector and a pre-expander optic configured to replicate an exit pupil of the projector in at least a first direction, the pre-expander optic comprising a plurality of spectrally-selective pupil-replicating elements to form at least two exit pupils at different spatial locations, each exit pupil being for a different spectral band. The display device further comprises a waveguide comprising at least two incoupling pupils, each incoupling pupil configured to receive light from a corresponding exit pupil of the pre-expander optic, and the waveguide configured to replicate each corresponding exit pupil in at least a second direction and output the light received toward an eyebox.

Eye-tracking with MEMS scanning and reflected light

An eye-tracking system is provided. The system includes an at least partially transparent visible light waveguide having a visible light display region configured to emit visible light to impinge upon an eye of a user. A light source is configured to emit at least infrared (IR) light that travels along an IR light path to impinge on the eye. A microelectromechanical system (MEMS) scanning mirror positioned in the IR light path is configured to direct the IR light along the IR light path. A relay positioned in the IR light path downstream of the MEMS scanning mirror includes at least one mirror configured to reflect the IR light along the IR light path. At least one sensor is configured to receive the IR light after being reflected by the eye.

Eye-tracking with MEMS scanning and optical relay

An eye-tracking system is provided that includes a light source configured to emit at least infrared (IR) light and a microelectromechanical system (MEMS) scanning mirror configured to direct the IR light. The system further includes a relay including at least one prism, and the relay is configured to receive the IR light directed by the MEMS scanning mirror and redirect the IR light. The system further includes a waveguide through which the IR light redirected by the relay passes to reach an eye, and at least one sensor configured to receive the IR light after being reflected by the eye.

Ionic devices with interacting species

An ionic device includes a layer of an ionic conductor containing first and second species of impurities. The first species of impurity in the layer is mobile in the ionic conductor, and a concentration profile of the first species determines a functional characteristic of the device. The second species of impurity in the layer interacts with the first species within the layer to create a structure that limits mobility of the first species in the layer.

STABLE C - (sup3) - CYCLOMETALATED PINCER COMPLEXES, THEIR PREPARATION AND USE AS CATALYSTS

The invention relates to a novel class of stable pincer complexes comprising a pinσer ligand linked to the metal via a Calfa cyclometalated carbon and via two donor atoms W1 and W2, wherein said Calfa carbon has a sp3 hybridization; said Calfa carbon is bonded to three Cbeta carbons; each of said Cbeta carbons is linked to the non-hydrogen atoms,- and W1 and W2 are independently selected from P, As, N or O. Said complexes are used as catalyst in transfer hydrogenation reactions such as reduction of ketones, reductions of imines and reductions of olefines.

Modified oligonucleotides and methods for their synthesis

Modified oligonucleotides that contain one or more of the phosphate groups substituted at phosphorus and methods for their synthesis are disclosed.

Single cell whole genome libraries for methylation sequencing

Provided herein are methods for preparing sequencing libraries for determining the methylation status of nucleic acids from a plurality of single cells. The present methods combine split-and-pool combinatorial indexing and bisulfite treatment techniques to characterize the methylation profiles of large numbers of single cells quickly, accurately and inexpensively.

Analysis of multiple analytes using a single assay

Embodiments of systems, methods, and compositions provided herein relate to methods of simultaneously analyzing multiple analytes in a single sample using a single assay. Some embodiments relate to simultaneous analysis of DNA and RNA in a single sample, for example, to the simultaneous generation of DNA and RNA libraries.

Methods for increasing yield of sequencing libraries

The present disclosure is concerned with compositions and methods for preparing a sequencing library. In one embodiment, methods include producing a library of target nucleic acids having the same adapter at each end and then switching the identity of one adapter to result in target nucleic acids flanked by distinct adapters.

Long indexed-linked read generation on transposome bound beads

Embodiments of systems, methods, and compositions provided herein relate to on bead tagmentation and droplet indexing. Some embodiments include performing co-assays on partitioned beads, including nucleic acid sequencing, indexed PCR, preparing nucleic acid libraries, determining m ethylation status, identifying genomic variants, or protein analysis..

Contiguity particle formation and methods of use

Embodiments of systems, methods, and compositions provided herein relate to hollow beads encapsulating single cells. Some embodiments include performing multiple co-assays on a single cell encapsulated within a hollow bead, including nucleic acid sequencing, preparing nucleic acid libraries, determining methylation status, identifying genomic variants, or protein analysis.

GNSS signal processing methods and apparatus

Methods and apparatus are presented for determining position a GNSS rover antenna from single-frequency observations of GNSS signals collected at the antenna over multiple epochs and from correction data for at least one of the epochs. Coded raw data prepared from the single-frequency observations in a binary format are obtained and decoded to obtain decoded raw data. The decoded raw data are used to construct multiple epochs of measurement data of time, range and phase. Correction data are obtained for at least one of the epochs. The measurement data are processed with the correction data in a realtime kinematic positioning engine to obtain a position estimate for each of a plurality of epochs.

GNSS signal processing methods and apparatus

Methods and apparatus are presented for determining a position of a GNSS rover antenna from observations collected at the antenna over multiple epochs from satellite signals of multiple GNSS, wherein the observation data of each GNSS has a distinct data format. The observation data of each GNSS are presented in a generic GNSS data format, which differs from the distinct data format of the GNSS, to obtain a set of generic data. A set of difference data is prepared representing differences between the converted observation data and the generic data. When at least four satellites are tracked, the generic data of the tracked satellites of multiple GNSS are used to compute a standalone antenna position. When at least five satellites are tracked, the generic data of the tracked satellites of multiple GNSS are used to compute a real-time kinematic antenna position.

Arrangement for building up crane tower

System and method for performing stimulation operations

A system and method is provided for performing stimulation operations at a wellsite having a subterranean formation with a reservoir therein. The method involves acquiring integrated wellsite data (e.g., geomechanical, geological, and/or geophysical properties of the formation, and/or geometrical properties of the mechanical discontinuities in the formation). The method also involves generating a mechanical earth model using the integrated wellsite data, and identifying a crossing behavior between an induced hydraulic fracture and at least one discontinuity in the formation. The method also involves optimizing a stimulation plan to achieve an optimized crossing behavior. The stimulation plan includes at least one of fluid viscosity, rate of injection of the fracturing fluid, and concentration of a fluid loss additive. The optimization may further include adjusting the stimulation plan to achieve the optimized crossing behavior between the induced hydraulic fracture and the discontinuity in the formation.

Ionic devices containing a membrane between layers

A device contains a first layer (420), a second layer (440); and a membrane (430) between the first and second layers (420, 440). Mobile ions (425) are in at least one of the first and second layers (420, 440), and the membrane (430) is permeable to the ions. Interfaces of the conductive membrane (430) with the first layer (420) and the second layer (440) are such that charge of a polarity of the ions (425) collects at the interfaces.

Methods of encapsulating single cells, the encapsulated cells and uses thereof

Embodiments of systems, methods, and compositions provided herein relate to hollow beads encapsulating single cells. Some embodiments include performing multiple co-assays on a single cell encapsulated within a hollow bead, including nucleic acid sequencing, preparing nucleic acid libraries, determining methylation status, identifying genomic variants, or protein analysis.

Liquid-crystal medium

The present invention relates to components for high-frequency technology, especially microwave components for high-frequency devices, such as devices for shifting the phase of microwaves, tunable filters, tunable metamaterial structures and electronic beam steering antennas (e.g. phased array antennas) comprising a liquid-crystalline medium, and to the liquid-crystalline medium used therein, wherein the liquid crystal medium comprises one or more compounds of formula (S) as defined in claim 1.

Liquid-crystalline medium

The present invention relates to liquid-crystalline media comprising one or more compounds of formula Cas defined in claim 1, and to high-frequency components comprising these media, especially microwave components for high-frequency devices, such as devices for shifting the phase of microwaves, tunable filters, tunable metamaterial structures, and electronic beam steering antennas (e.g. phased array antennas).